MCID: ACN003
MIFTS: 41

Acneiform Dermatitis

Categories: Skin diseases

Aliases & Classifications for Acneiform Dermatitis

MalaCards integrated aliases for Acneiform Dermatitis:

Name: Acneiform Dermatitis 12 15
Dermatitis Acneiform 73

Classifications:



External Ids:

Disease Ontology 12 DOID:4399
NCIt 50 C35277
UMLS 73 C0234894

Summaries for Acneiform Dermatitis

MalaCards based summary : Acneiform Dermatitis, also known as dermatitis acneiform, is related to sigmoid neoplasm and periampullary adenoma. An important gene associated with Acneiform Dermatitis is UBR5 (Ubiquitin Protein Ligase E3 Component N-Recognin 5), and among its related pathways/superpathways are Innate Immune System and Apoptotic Pathways in Synovial Fibroblasts. The drugs Carboplatin and Paclitaxel have been mentioned in the context of this disorder. Affiliated tissues include skin and lung, and related phenotypes are Decreased viability and Decreased viability

Related Diseases for Acneiform Dermatitis

Diseases related to Acneiform Dermatitis via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50) (show all 106)
# Related Disease Score Top Affiliating Genes
1 sigmoid neoplasm 10.8 HRAS KRAS
2 periampullary adenoma 10.7 HRAS KRAS
3 bile duct cysts 10.7 HRAS KRAS
4 secondary hypertrophic osteoarthropathy 10.6 HRAS KRAS
5 giant congenital nevus 10.6 HRAS NRAS
6 nasal cavity adenocarcinoma 10.6 HRAS KRAS
7 anal canal adenocarcinoma 10.6 HRAS KRAS
8 ovary serous adenocarcinoma 10.5 HRAS KRAS
9 benign struma ovarii 10.5 HRAS NRAS
10 melanomatosis 10.5 HRAS NRAS
11 marcus gunn phenomenon 10.5 HRAS NRAS
12 malignant struma ovarii 10.4 HRAS NRAS
13 ampulla of vater neoplasm 10.4 HRAS KRAS
14 pulmonic stenosis 10.4 HRAS KRAS MAP2K1
15 costello syndrome 10.4 HRAS KRAS MAP2K1
16 bronchiolo-alveolar adenocarcinoma 10.4 EGFR KRAS
17 malignant conjunctival melanoma 10.3 HRAS MAP2K7 NRAS
18 ovarian cystadenocarcinoma 10.3 HRAS KRAS
19 schimmelpenning-feuerstein-mims syndrome 10.3 HRAS KRAS NRAS
20 integumentary system cancer 10.3 HRAS MAP2K7 NRAS
21 core binding factor acute myeloid leukemia 10.3 HRAS KRAS NRAS
22 liver angiosarcoma 10.3 HRAS KRAS NRAS
23 myelodysplastic myeloproliferative cancer 10.2 HRAS NRAS
24 breast intraductal proliferative lesion 10.2 EGFR ERBB2
25 nail disease 10.2 EGFR KRAS
26 ovarian melanoma 10.2 HRAS MAP2K1 NRAS
27 mixed cell type cancer 10.2 ERBB2 HRAS KRAS
28 ovary adenocarcinoma 10.2 ERBB2 HRAS KRAS
29 intracystic papillary adenoma 10.2 EGFR ERBB2
30 autoimmune lymphoproliferative syndrome 10.2 HRAS KRAS NRAS
31 lung benign neoplasm 10.2 EGFR HRAS KRAS
32 progesterone-receptor negative breast cancer 10.2 EGFR ERBB2
33 breast scirrhous carcinoma 10.2 EGFR ERBB2
34 vulvar melanoma 10.1 EIF2AK3 HRAS NRAS
35 colorectal adenocarcinoma 10.1 EGFR HRAS KRAS
36 oncocytic breast carcinoma 10.1 EGFR ERBB2
37 paget disease, extramammary 10.1 ERBB2 ERBB4
38 rare adenocarcinoma of the breast 10.1 KRAS PIK3CA
39 prostate adenoid cystic carcinoma 10.1 HRAS PIK3CA
40 cardiofaciocutaneous syndrome 1 10.1 HRAS KRAS MAP2K1 MAP2K7
41 breast adenoid cystic carcinoma 10.1 EGFR ERBB2
42 microglandular adenosis 10.0 EGFR ERBB2
43 pulmonary blastoma 10.0 EGFR KRAS
44 paronychia 9.9 EGFR HRAS KRAS MAP2K7
45 small intestinal adenocarcinoma 9.9 EGFR ERBB2 KRAS
46 leukemia, acute myeloid 9.9 HRAS KRAS MAP2K7 NRAS
47 apocrine adenoma 9.9 HRAS KRAS PIK3CA
48 endometrial adenocarcinoma 9.9 EGFR ERBB2 KRAS
49 transitional cell carcinoma 9.9 EGFR ERBB2 HRAS
50 aggressive digital papillary adenocarcinoma 9.9 HRAS KRAS PIK3CA

Graphical network of the top 20 diseases related to Acneiform Dermatitis:



Diseases related to Acneiform Dermatitis

Symptoms & Phenotypes for Acneiform Dermatitis

GenomeRNAi Phenotypes related to Acneiform Dermatitis according to GeneCards Suite gene sharing:

26 (show all 23)
# Description GenomeRNAi Source Accession Score Top Affiliating Genes
1 Decreased viability GR00055-A-2 10.84 KRAS PIK3CA EGFR HRAS
2 Decreased viability GR00106-A-0 10.84 KRAS
3 Decreased viability GR00107-A-1 10.84 MAP2K1
4 Decreased viability GR00221-A-1 10.84 MAP2K7 KRAS NRAS PIK3CA HRAS EGFR
5 Decreased viability GR00221-A-2 10.84 KRAS PIK3CA HRAS EIF2AK3
6 Decreased viability GR00221-A-3 10.84 HRAS MAP2K1 NRAS ERBB2
7 Decreased viability GR00221-A-4 10.84 PIK3CA ERBB2 EGFR EIF2AK3
8 Decreased viability GR00301-A 10.84 KRAS ERBB4
9 Decreased viability GR00342-S-1 10.84 MAP2K7 MAP2K1 ERBB4
10 Decreased viability GR00342-S-2 10.84 MAP2K1
11 Decreased viability GR00342-S-3 10.84 MAP2K1
12 Decreased viability GR00381-A-1 10.84 KRAS
13 Decreased viability GR00402-S-2 10.84 MAP2K1 KRAS MAP2K7 NRAS PIK3CA HRAS
14 Decreased shRNA abundance (Z-score < -2) GR00366-A-211 9.86 UBR5
15 Decreased shRNA abundance (Z-score < -2) GR00366-A-27 9.86 EIF2AK3
16 Decreased shRNA abundance (Z-score < -2) GR00366-A-48 9.86 UBR5
17 Decreased shRNA abundance (Z-score < -2) GR00366-A-58 9.86 UBR5 EGFR EIF2AK3
18 Decreased shRNA abundance (Z-score < -2) GR00366-A-60 9.86 EIF2AK3
19 Decreased shRNA abundance (Z-score < -2) GR00366-A-91 9.86 EGFR
20 Decreased cell migration GR00055-A-1 9.77 KRAS PIK3CA ERBB4 EGFR HRAS
21 Decreased focal adhesion (FA) area, decreased FA length, decreased FA mean intensity, increased number of small and round FAs, increased FA abundance GR00210-A 9.72 NRAS ERBB4 EGFR HRAS ERBB2
22 Increased cell migration GR00055-A-3 9.02 KRAS PIK3CA EGFR ERBB4 HRAS
23 Decreased viability in Von Hippel-Lindau (VHL) (-/-) cell line GR00121-A 8.96 MAP2K1 ERBB4

MGI Mouse Phenotypes related to Acneiform Dermatitis:

46 (show all 18)
# Description MGI Source Accession Score Top Affiliating Genes
1 cardiovascular system MP:0005385 10.31 HRAS MAP2K1 KRAS NRAS SPEN UBR5
2 endocrine/exocrine gland MP:0005379 10.29 HRAS MAP2K1 KRAS MAP2K7 NRAS SPEN
3 cellular MP:0005384 10.26 KRAS ERBB4 MAP2K1 PIK3CA MAP2K7 NRAS
4 growth/size/body region MP:0005378 10.24 HRAS MAP2K1 KRAS SPEN NRAS UBR5
5 behavior/neurological MP:0005386 10.23 ERBB4 KRAS HRAS MAP2K7 PIK3CA SPEN
6 homeostasis/metabolism MP:0005376 10.22 HRAS MAP2K1 KRAS MAP2K7 NRAS UBR5
7 mortality/aging MP:0010768 10.22 HRAS MAP2K1 KRAS MAP2K7 NRAS SPEN
8 integument MP:0010771 10.16 HRAS MAP2K1 KRAS NRAS SPEN PIK3CA
9 craniofacial MP:0005382 10.15 HRAS MAP2K1 KRAS ERBB4 NRAS UBR5
10 embryo MP:0005380 10.13 KRAS ERBB4 MAP2K1 PIK3CA NRAS UBR5
11 digestive/alimentary MP:0005381 10.08 KRAS HRAS MAP2K1 NRAS EIF2AK3 ERBB2
12 nervous system MP:0003631 10.06 HRAS MAP2K1 KRAS ERBB4 SPEN UBR5
13 neoplasm MP:0002006 9.97 HRAS MAP2K1 KRAS NRAS PIK3CA MAP2K7
14 liver/biliary system MP:0005370 9.91 KRAS SPEN NRAS EIF2AK3 CYP1A1 EGFR
15 normal MP:0002873 9.81 HRAS MAP2K1 KRAS ERBB4 NRAS MAP2K7
16 no phenotypic analysis MP:0003012 9.8 KRAS HRAS PIK3CA NRAS EIF2AK3 CYP1A1
17 reproductive system MP:0005389 9.5 ERBB4 KRAS MAP2K1 MAP2K7 PIK3CA ERBB2
18 skeleton MP:0005390 9.23 KRAS HRAS MAP2K1 PIK3CA NRAS EIF2AK3

Drugs & Therapeutics for Acneiform Dermatitis

Drugs for Acneiform Dermatitis (from DrugBank, HMDB, Dgidb, PharmGKB, IUPHAR, NovoSeek, BitterDB):

(show top 50) (show all 67)
# Name Status Phase Clinical Trials Cas Number PubChem Id
1
Carboplatin Approved Phase 3 41575-94-4 10339178 498142 38904
2
Paclitaxel Approved, Vet_approved Phase 3 33069-62-4 36314
3
Cetuximab Approved Phase 3 205923-56-4 56842117 2333
4
Docetaxel Approved, Investigational Phase 3 114977-28-5 148124
5 taxane Phase 3
6 Albumin-Bound Paclitaxel Phase 3
7 Antimitotic Agents Phase 3
8 Antineoplastic Agents, Phytogenic Phase 3,Phase 2
9
Hydrocortisone Approved, Vet_approved Phase 2 50-23-7 5754
10
Ciprofloxacin Approved, Investigational Phase 2 85721-33-1 2764
11
Irinotecan Approved, Investigational Phase 2 97682-44-5, 100286-90-6 60838
12
Doxycycline Approved, Investigational, Vet_approved Phase 2 564-25-0 54671203
13
Hydroxyzine Approved Phase 2 68-88-2 3658
14
Silver sulfadiazine Approved, Vet_approved Phase 2 22199-08-2 441244
15
Sulfadiazine Approved, Investigational, Vet_approved Phase 2 68-35-9 5215
16
Prednisolone Approved, Vet_approved Phase 2 50-24-8 5755
17
Amoxicillin Approved, Vet_approved Phase 2 26787-78-0 33613
18
Clindamycin Approved, Vet_approved Phase 2 18323-44-9 29029
19
Methylprednisolone Approved, Vet_approved Phase 2 83-43-2 6741
20
Fluorouracil Approved Phase 2 51-21-8 3385
21
Petrolatum Approved, Investigational Phase 2 8009-03-8
22
leucovorin Approved, Nutraceutical Phase 2 58-05-9 143 6006
23
Camptothecin Experimental Phase 2 7689-03-4
24
Butyric Acid Experimental, Investigational Phase 2 107-92-6 264
25 Clavulanic Acid Phase 2
26 Prednisolone acetate Phase 2
27 glucocorticoids Phase 2
28 topoisomerase I inhibitors Phase 2
29 Methylprednisolone acetate Phase 2
30 Methylprednisolone Hemisuccinate Phase 2
31 Alclometasone dipropionate Phase 2
32 Gastrointestinal Agents Phase 2
33 Clindamycin palmitate Phase 2
34 Clindamycin phosphate Phase 2
35 Neuroprotective Agents Phase 2
36 Sunscreening Agents Phase 2
37 Cortisol succinate Phase 2
38 Histamine Antagonists Phase 2
39 Histamine H1 Antagonists Phase 2
40 Topoisomerase Inhibitors Phase 2
41 Hormone Antagonists Phase 2
42 Dermatologic Agents Phase 2
43 Hormones Phase 2
44 Hormones, Hormone Substitutes, and Hormone Antagonists Phase 2
45 Hydrocortisone 17-butyrate 21-propionate Phase 2
46 Emollients Phase 2
47 Hydrocortisone acetate Phase 2
48 Hydrocortisone-17-butyrate Phase 2
49 Peripheral Nervous System Agents Phase 2
50 Anti-Bacterial Agents Phase 2

Interventional clinical trials:


# Name Status NCT ID Phase Drugs
1 Study of Taxane/Carboplatin +/- Cetuximab as First-Line Treatment for Patients With Advanced/Metastatic Non-Small Cell Lung Cancer Completed NCT00112294 Phase 3 Paclitaxel (Taxane);Docetaxel (Taxane);Carboplatin;Cetuximab
2 Skin Toxicity Treatment in Metastatic Colorectal Cancer (mCRC) Patients Receiving Panitumumab + Irinotecan-based Therapy Completed NCT00332163 Phase 2 Irinotecan;FOLFIRI;Pre-emptive Skin Treatment;Reactive Skin Treatment
3 Study Of Dacomitinib (PF-00299804) In Advanced NSCLC Patients (Post Chemo Or Select First Line) To Evaluate Prophylactic Intervention On Derm And GI AEs And PRO Completed NCT01465802 Phase 2 Dacomitinib;Dacomitinib;Doxycycline;Probiotic;Alclometasone cream

Search NIH Clinical Center for Acneiform Dermatitis

Genetic Tests for Acneiform Dermatitis

Anatomical Context for Acneiform Dermatitis

MalaCards organs/tissues related to Acneiform Dermatitis:

41
Skin, Lung

Publications for Acneiform Dermatitis

Variations for Acneiform Dermatitis

Expression for Acneiform Dermatitis

Search GEO for disease gene expression data for Acneiform Dermatitis.

Pathways for Acneiform Dermatitis

Pathways related to Acneiform Dermatitis according to GeneCards Suite gene sharing:

(show top 50) (show all 167)
# Super pathways Score Top Affiliating Genes
1
Show member pathways
14.06 EGFR ERBB2 ERBB4 HRAS KRAS MAP2K1
2
Show member pathways
13.92 EGFR EIF2AK3 ERBB2 ERBB4 HRAS KRAS
3
Show member pathways
13.89 EGFR ERBB2 ERBB4 HRAS KRAS MAP2K1
4
Show member pathways
13.79 EGFR ERBB2 ERBB4 HRAS KRAS MAP2K1
5
Show member pathways
13.77 EGFR ERBB2 ERBB4 HRAS KRAS MAP2K1
6
Show member pathways
13.74 EGFR ERBB2 ERBB4 HRAS KRAS MAP2K1
7
Show member pathways
13.6 EGFR ERBB2 ERBB4 HRAS KRAS MAP2K1
8
Show member pathways
13.6 EGFR ERBB2 ERBB4 HRAS KRAS MAP2K1
9
Show member pathways
13.59 EGFR ERBB2 ERBB4 HRAS KRAS MAP2K1
10
Show member pathways
13.52 EGFR ERBB2 ERBB4 HRAS KRAS NRAS
11
Show member pathways
13.48 EGFR HRAS KRAS MAP2K1 MAP2K7 NRAS
12
Show member pathways
13.47 EGFR ERBB2 ERBB4 HRAS KRAS MAP2K1
13
Show member pathways
13.44 EGFR ERBB2 ERBB4 HRAS KRAS NRAS
14
Show member pathways
13.41 EGFR ERBB2 ERBB4 HRAS KRAS MAP2K1
15
Show member pathways
13.39 EGFR EIF2AK3 ERBB2 ERBB4 HRAS KRAS
16
Show member pathways
13.35 EGFR ERBB2 HRAS KRAS MAP2K7 NRAS
17
Show member pathways
13.16 EGFR HRAS KRAS MAP2K1 MAP2K7 NRAS
18
Show member pathways
13.1 EGFR HRAS KRAS MAP2K1 NRAS
19
Show member pathways
13.09 EGFR HRAS KRAS MAP2K1 NRAS
20
Show member pathways
13.08 EGFR HRAS KRAS MAP2K1 NRAS
21
Show member pathways
13.08 EGFR ERBB2 ERBB4 HRAS KRAS MAP2K1
22
Show member pathways
13.07 EGFR HRAS KRAS MAP2K1 NRAS
23
Show member pathways
13.06 HRAS KRAS MAP2K1 MAP2K7 NRAS
24
Show member pathways
13.02 EGFR HRAS KRAS MAP2K1 NRAS PIK3CA
25
Show member pathways
13.01 EGFR ERBB2 HRAS KRAS MAP2K1 NRAS
26
Show member pathways
13.01 EGFR EIF2AK3 ERBB2 HRAS KRAS MAP2K1
27
Show member pathways
13 EGFR ERBB2 HRAS KRAS MAP2K1 MAP2K7
28
Show member pathways
12.99 HRAS KRAS MAP2K1 MAP2K7 NRAS
29
Show member pathways
12.98 HRAS KRAS MAP2K1 MAP2K7 NRAS
30
Show member pathways
12.97 HRAS KRAS MAP2K1 MAP2K7 NRAS
31 12.97 EGFR ERBB2 HRAS KRAS MAP2K1 NRAS
32
Show member pathways
12.96 HRAS KRAS MAP2K1 NRAS PIK3CA
33
Show member pathways
12.94 EIF2AK3 HRAS KRAS MAP2K1 NRAS PIK3CA
34
Show member pathways
12.92 HRAS KRAS MAP2K1 NRAS PIK3CA
35
Show member pathways
12.92 EGFR ERBB2 ERBB4 HRAS KRAS MAP2K1
36
Show member pathways
12.9 EGFR ERBB2 HRAS KRAS MAP2K1 NRAS
37
Show member pathways
12.9 EGFR ERBB2 ERBB4 HRAS KRAS MAP2K1
38
Show member pathways
12.89 HRAS KRAS MAP2K1 MAP2K7 NRAS
39
Show member pathways
12.88 HRAS KRAS MAP2K1 MAP2K7 NRAS
40
Show member pathways
12.87 EGFR HRAS KRAS MAP2K1 NRAS PIK3CA
41
Show member pathways
12.86 EGFR ERBB2 ERBB4 HRAS KRAS NRAS
42
Show member pathways
12.85 EGFR ERBB2 HRAS KRAS MAP2K1 MAP2K7
43
Show member pathways
12.84 ERBB2 HRAS KRAS MAP2K1 MAP2K7 NRAS
44
Show member pathways
12.83 EGFR HRAS KRAS MAP2K1 NRAS
45 12.83 EGFR ERBB2 ERBB4 HRAS KRAS MAP2K1
46
Show member pathways
12.81 EGFR HRAS KRAS MAP2K1 MAP2K7 NRAS
47
Show member pathways
12.79 EGFR HRAS KRAS MAP2K1 MAP2K7 NRAS
48
Show member pathways
12.77 EGFR HRAS KRAS MAP2K1 NRAS
49 12.77 EGFR HRAS KRAS MAP2K1 NRAS PIK3CA
50
Show member pathways
12.74 EGFR ERBB2 HRAS KRAS NRAS PIK3CA

GO Terms for Acneiform Dermatitis

Cellular components related to Acneiform Dermatitis according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 cytoplasm GO:0005737 9.9 CYP1A1 EGFR EIF2AK3 ERBB2 ERBB4 HRAS
2 perinuclear region of cytoplasm GO:0048471 9.35 EGFR EIF2AK3 ERBB2 HRAS UBR5
3 basal plasma membrane GO:0009925 8.8 EGFR ERBB2 ERBB4

Biological processes related to Acneiform Dermatitis according to GeneCards Suite gene sharing:

(show all 39)
# Name GO ID Score Top Affiliating Genes
1 phosphorylation GO:0016310 9.98 EGFR EIF2AK3 ERBB2 ERBB4 MAP2K1 MAP2K7
2 positive regulation of ERK1 and ERK2 cascade GO:0070374 9.95 EGFR ERBB2 ERBB4 HRAS MAP2K1
3 positive regulation of gene expression GO:0010628 9.95 EIF2AK3 ERBB2 HRAS KRAS MAP2K1 UBR5
4 cell proliferation GO:0008283 9.93 CYP1A1 EGFR ERBB2 ERBB4 HRAS UBR5
5 leukocyte migration GO:0050900 9.92 HRAS KRAS NRAS PIK3CA
6 axon guidance GO:0007411 9.91 HRAS KRAS NRAS PIK3CA
7 protein autophosphorylation GO:0046777 9.9 EGFR EIF2AK3 ERBB2 ERBB4
8 Fc-epsilon receptor signaling pathway GO:0038095 9.89 HRAS KRAS MAP2K7 NRAS PIK3CA
9 positive regulation of protein kinase B signaling GO:0051897 9.88 EGFR ERBB2 ERBB4 PIK3CA
10 positive regulation of MAPK cascade GO:0043410 9.88 EGFR ERBB2 ERBB4 HRAS
11 protein phosphorylation GO:0006468 9.87 EGFR EIF2AK3 ERBB2 ERBB4 MAP2K1 MAP2K7
12 phosphatidylinositol phosphorylation GO:0046854 9.86 EGFR ERBB2 ERBB4 PIK3CA
13 negative regulation of neuron apoptotic process GO:0043524 9.85 HRAS KRAS PIK3CA
14 transmembrane receptor protein tyrosine kinase signaling pathway GO:0007169 9.84 EGFR ERBB2 ERBB4
15 stimulatory C-type lectin receptor signaling pathway GO:0002223 9.84 HRAS KRAS NRAS
16 liver development GO:0001889 9.84 CYP1A1 EGFR KRAS PIK3CA
17 negative regulation of signal transduction GO:0009968 9.83 EGFR ERBB2 ERBB4
18 activation of protein kinase activity GO:0032147 9.83 MAP2K1 MAP2K7 PIK3CA
19 Ras protein signal transduction GO:0007265 9.82 HRAS KRAS NRAS
20 positive regulation of kinase activity GO:0033674 9.81 EGFR ERBB2 ERBB4
21 positive regulation of MAP kinase activity GO:0043406 9.81 EGFR ERBB2 HRAS KRAS
22 positive regulation of epithelial cell proliferation GO:0050679 9.8 EGFR ERBB2 HRAS
23 peptidyl-tyrosine phosphorylation GO:0018108 9.8 EGFR ERBB2 ERBB4 MAP2K1 MAP2K7
24 cellular response to epidermal growth factor stimulus GO:0071364 9.77 EGFR ERBB2 ERBB4
25 positive regulation of protein phosphorylation GO:0001934 9.77 EGFR ERBB2 ERBB4 HRAS KRAS
26 regulation of cell motility GO:2000145 9.74 EGFR ERBB2 ERBB4
27 negative regulation of ERBB signaling pathway GO:1901185 9.7 EGFR ERBB2 ERBB4
28 cellular senescence GO:0090398 9.68 HRAS MAP2K1
29 regulation of long-term neuronal synaptic plasticity GO:0048169 9.68 HRAS KRAS
30 response to osmotic stress GO:0006970 9.67 EGFR MAP2K7
31 positive regulation of transcription by RNA polymerase I GO:0045943 9.65 EIF2AK3 ERBB2
32 positive regulation of production of miRNAs involved in gene silencing by miRNA GO:1903800 9.65 EGFR MAP2K1
33 signal transduction by protein phosphorylation GO:0023014 9.65 EGFR ERBB2 ERBB4 MAP2K1 MAP2K7
34 response to isolation stress GO:0035900 9.63 HRAS KRAS
35 proteolysis in other organism GO:0035897 9.63 MAP2K1 MAP2K7
36 epidermal growth factor receptor signaling pathway GO:0007173 9.55 EGFR HRAS KRAS NRAS PIK3CA
37 MAPK cascade GO:0000165 9.5 EGFR ERBB2 ERBB4 HRAS KRAS MAP2K1
38 ERBB2 signaling pathway GO:0038128 9.17 EGFR ERBB2 ERBB4 HRAS KRAS NRAS
39 signal transduction GO:0007165 10.21 EGFR ERBB2 ERBB4 HRAS KRAS MAP2K1

Molecular functions related to Acneiform Dermatitis according to GeneCards Suite gene sharing:

(show all 17)
# Name GO ID Score Top Affiliating Genes
1 protein kinase activity GO:0004672 9.88 EGFR EIF2AK3 ERBB2 ERBB4 MAP2K1 MAP2K7
2 protein serine/threonine kinase activity GO:0004674 9.87 EIF2AK3 MAP2K1 MAP2K7 PIK3CA
3 enzyme binding GO:0019899 9.86 CYP1A1 EGFR EIF2AK3 MAP2K7
4 kinase activity GO:0016301 9.8 EGFR EIF2AK3 ERBB2 ERBB4 MAP2K1 MAP2K7
5 Ras guanyl-nucleotide exchange factor activity GO:0005088 9.71 EGFR ERBB2 ERBB4
6 MAP kinase kinase kinase activity GO:0004709 9.69 EGFR ERBB2 ERBB4
7 mitogen-activated protein kinase kinase binding GO:0031434 9.67 EGFR ERBB2 ERBB4
8 protein phosphatase binding GO:0019903 9.67 EGFR EIF2AK3 ERBB2 MAP2K7
9 transmembrane receptor protein tyrosine kinase activity GO:0004714 9.63 EGFR ERBB2 ERBB4
10 phosphatidylinositol-4,5-bisphosphate 3-kinase activity GO:0046934 9.62 EGFR ERBB2 ERBB4 PIK3CA
11 MAP kinase kinase activity GO:0004708 9.55 MAP2K1 MAP2K7
12 protein tyrosine kinase activity GO:0004713 9.35 EGFR ERBB2 ERBB4 MAP2K1 MAP2K7
13 obsolete signal transducer, downstream of receptor, with protein tyrosine kinase activity GO:0004716 9.33 EGFR ERBB2 ERBB4
14 nucleotide binding GO:0000166 9.17 EGFR ERBB2 ERBB4 HRAS KRAS MAP2K1
15 protein binding GO:0005515 10.34 CYP1A1 EGFR EIF2AK3 ERBB2 ERBB4 HRAS
16 transferase activity GO:0016740 10.03 EGFR EIF2AK3 ERBB2 ERBB4 MAP2K1 MAP2K7
17 ATP binding GO:0005524 10.02 EGFR EIF2AK3 ERBB2 ERBB4 MAP2K1 MAP2K7

Sources for Acneiform Dermatitis

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
17 ExPASy
19 FMA
28 GO
29 GTR
30 HGMD
31 HMDB
32 HPO
33 ICD10
34 ICD10 via Orphanet
35 ICD9CM
36 IUPHAR
37 KEGG
38 LifeMap
40 LOVD
42 MedGen
44 MeSH
45 MESH via Orphanet
46 MGI
49 NCI
50 NCIt
51 NDF-RT
54 NINDS
55 Novoseek
57 OMIM
58 OMIM via Orphanet
62 PubMed
64 QIAGEN
69 SNOMED-CT via HPO
70 SNOMED-CT via Orphanet
71 TGDB
72 Tocris
73 UMLS
74 UMLS via Orphanet
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