MCID: ACQ041
MIFTS: 21

Acquired Amegakaryocytic Thrombocytopenia

Categories: Rare diseases, Blood diseases, Genetic diseases

Aliases & Classifications for Acquired Amegakaryocytic Thrombocytopenia

MalaCards integrated aliases for Acquired Amegakaryocytic Thrombocytopenia:

Name: Acquired Amegakaryocytic Thrombocytopenia 53 73
Acquired Pure Megakaryocytic Aplasia 53 73
Severe Thrombocytopenia and Selective, Marked Decrease or Absence of Megakaryocytes 53
Aat 53

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Summaries for Acquired Amegakaryocytic Thrombocytopenia

NIH Rare Diseases : 53 Acquired amegakaryocytic thrombocytopenia is a rare blood disorder that causes severe thrombocytopenia with no other blood abnormalities. It is so named because the level of large bone marrow cells that produce platelets, called megakaryocytes, are significantly lower or absent. Signs and symptoms of the condition include prolonged bleeding; easy bruising; rash (pinpoint red spots called petechia); bleeding in the mouth and gums; and/or frequent nosebleeds. There are many potential causes of the condition. Although standard treatment guidelines have not been established, various immunosuppressive treatment approaches have been utilized with success in affected people. 

MalaCards based summary : Acquired Amegakaryocytic Thrombocytopenia, also known as acquired pure megakaryocytic aplasia, is related to alpha-1-antitrypsin deficiency and thrombocytopenia. An important gene associated with Acquired Amegakaryocytic Thrombocytopenia is LOC107963955 (BCR-ABL Major-Breakpoint Cluster Region). Affiliated tissues include bone and bone marrow.

Related Diseases for Acquired Amegakaryocytic Thrombocytopenia

Graphical network of the top 20 diseases related to Acquired Amegakaryocytic Thrombocytopenia:



Diseases related to Acquired Amegakaryocytic Thrombocytopenia

Symptoms & Phenotypes for Acquired Amegakaryocytic Thrombocytopenia

Drugs & Therapeutics for Acquired Amegakaryocytic Thrombocytopenia

Search Clinical Trials , NIH Clinical Center for Acquired Amegakaryocytic Thrombocytopenia

Genetic Tests for Acquired Amegakaryocytic Thrombocytopenia

Anatomical Context for Acquired Amegakaryocytic Thrombocytopenia

MalaCards organs/tissues related to Acquired Amegakaryocytic Thrombocytopenia:

41
Bone, Bone Marrow

Publications for Acquired Amegakaryocytic Thrombocytopenia

Articles related to Acquired Amegakaryocytic Thrombocytopenia:

(show all 20)
# Title Authors Year
1
Acquired Amegakaryocytic Thrombocytopenia and Pure Red Cell Aplasia in Thymoma. ( 29713553 )
2018
2
Acquired amegakaryocytic thrombocytopenia and red cell aplasia in a patient with thymoma progressing to aplastic anemia successfully treated with allogenic stem cell transplantation. ( 29409729 )
2018
3
Acquired amegakaryocytic thrombocytopenia previously diagnosed as idiopathic thrombocytopenic purpura in a patient with hepatitis C virus infection. ( 29085203 )
2017
4
Mononeuritis multiplex in acquired amegakaryocytic thrombocytopenia. ( 26752909 )
2015
5
Acquired amegakaryocytic thrombocytopenia in a patient with occupational chemical exposure. ( 22314209 )
2014
6
"Almost bleeding to death": the conundrum of acquired amegakaryocytic thrombocytopenia. ( 24649385 )
2014
7
Thymoma complicated by acquired amegakaryocytic thrombocytopenia and pure red cell aplasia. ( 25361796 )
2014
8
Acquired amegakaryocytic thrombocytopenia purpura in a Rhesus macaque (Macaca mulatta). ( 22776057 )
2012
9
Acquired amegakaryocytic thrombocytopenia: potential role of thrombopoietin receptor agonists. ( 21326159 )
2010
10
Effective use of rituximab for acquired amegakaryocytic thrombocytopenia. ( 20981676 )
2010
11
Acquired amegakaryocytic thrombocytopenia and pure red cell aplasia associated with an occult large granular lymphocyte leukemia. ( 17915315 )
2008
12
Successful treatment of acquired amegakaryocytic thrombocytopenia with cyclosporine in adult onset Still's disease. ( 16957888 )
2007
13
Rapid progression of acquired amegakaryocytic thrombocytopenia to myelodysplastic syndrome: case report. ( 27265013 )
2005
14
Acquired amegakaryocytic thrombocytopenia associated with proliferation of gamma/delta TCR T-lymphocytes and a BCR-ABL (p210) fusion transcript. ( 15458517 )
2004
15
Acquired amegakaryocytic thrombocytopenia purpura and eosinophilic fasciitis: a long relapsing and remitting course. ( 14978695 )
2004
16
Acquired amegakaryocytic thrombocytopenia--four cases and a literature review. ( 15515801 )
2004
17
Successful treatment of acquired pure red cell aplasia and acquired amegakaryocytic thrombocytopenia with anti-thymocyte globulin. ( 11421300 )
2001
18
Acquired amegakaryocytic thrombocytopenia treated with allogeneic BMT: a case report and review of the literature. ( 10627644 )
1999
19
Rapid progression of acquired amegakaryocytic thrombocytopenia to aplastic anemia. ( 9003837 )
1997
20
Acquired amegakaryocytic thrombocytopenia: report of a case and review of literature. ( 2690174 )
1989

Variations for Acquired Amegakaryocytic Thrombocytopenia

Expression for Acquired Amegakaryocytic Thrombocytopenia

Search GEO for disease gene expression data for Acquired Amegakaryocytic Thrombocytopenia.

Pathways for Acquired Amegakaryocytic Thrombocytopenia

GO Terms for Acquired Amegakaryocytic Thrombocytopenia

Sources for Acquired Amegakaryocytic Thrombocytopenia

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