MCID: ACQ006
MIFTS: 23

Acquired Gastric Outlet Stenosis

Categories: Gastrointestinal diseases

Aliases & Classifications for Acquired Gastric Outlet Stenosis

MalaCards integrated aliases for Acquired Gastric Outlet Stenosis:

Name: Acquired Gastric Outlet Stenosis 12 15
Adult Hypertrophic Pyloric Stenosis 12 71 32
Acquired Hypertrophic Pyloric Stenosis 12

Classifications:



External Ids:

Disease Ontology 12 DOID:14099
ICD9CM 34 537.0
SNOMED-CT 67 13483000
ICD10 32 K31.1
UMLS 71 C0700588 C2937286

Summaries for Acquired Gastric Outlet Stenosis

MalaCards based summary : Acquired Gastric Outlet Stenosis, also known as adult hypertrophic pyloric stenosis, is related to gastric dilatation and pyloric stenosis. An important gene associated with Acquired Gastric Outlet Stenosis is UCHL1 (Ubiquitin C-Terminal Hydrolase L1). Affiliated tissues include cervix, and related phenotype is digestive/alimentary.

Related Diseases for Acquired Gastric Outlet Stenosis

Diseases related to Acquired Gastric Outlet Stenosis via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50) (show all 140)
# Related Disease Score Top Affiliating Genes
1 gastric dilatation 30.0 ATP4A ATP12A
2 pyloric stenosis 10.9
3 hypertrophic pyloric stenosis 10.8
4 gastroparesis 10.1
5 megaesophagus 10.1
6 crohn's disease 10.1
7 achalasia 10.1
8 idiopathic gastroparesis 10.1
9 vagus nerve disease 9.9 ATP4A ATP12A
10 necrotizing gastritis 9.9 ATP4A ATP12A
11 scalp dermatosis 9.9 ATP4A ATP12A
12 hemangioma of intra-abdominal structure 9.9 ATP4A ATP12A
13 lingual goiter 9.9 ATP4A ATP12A
14 displacement of cardia through esophageal hiatus 9.9 ATP4A ATP12A
15 bacterial esophagitis 9.9 ATP4A ATP12A
16 cascade stomach 9.9 ATP4A ATP12A
17 benzylpenicillin allergy 9.9 ATP4A ATP12A
18 median arcuate ligament syndrome 9.9 ATP4A ATP12A
19 afferent loop syndrome 9.9 ATP4A ATP12A
20 cervix erosion 9.9 ATP4A ATP12A
21 angiodysplasia of intestine 9.9 ATP4A ATP12A
22 angiodysplasia 9.9 ATP4A ATP12A
23 granulomatous gastritis 9.9 ATP4A ATP12A
24 laryngeal tuberculosis 9.9 ATP4A ATP12A
25 fungal esophagitis 9.9 ATP4A ATP12A
26 dieulafoy lesion 9.9 ATP4A ATP12A
27 esophagus melanoma 9.9 ATP4A ATP12A
28 cefuroxime allergy 9.9 ATP4A ATP12A
29 emphysematous cholecystitis 9.9 ATP4A ATP12A
30 gastric gastrinoma 9.9 ATP4A ATP12A
31 superior mesenteric artery syndrome 9.9 ATP4A ATP12A
32 pneumatosis cystoides intestinalis 9.9 ATP4A ATP12A
33 chronic laryngitis 9.9 ATP4A ATP12A
34 laryngitis 9.9 ATP4A ATP12A
35 peptic ulcer perforation 9.9 ATP4A ATP12A
36 viral laryngitis 9.9 ATP4A ATP12A
37 gastroduodenal crohn's disease 9.9 ATP4A ATP12A
38 polyposis, skin pigmentation, alopecia, and fingernail changes 9.9 ATP4A ATP12A
39 central nervous system origin vertigo 9.9 ATP4A ATP12A
40 rumination disorder 9.9 ATP4A ATP12A
41 internal hemorrhoid 9.9 ATP4A ATP12A
42 hemorrhoid 9.9 ATP4A ATP12A
43 acute laryngitis 9.9 ATP4A ATP12A
44 gastroduodenitis 9.9 ATP4A ATP12A
45 duodenitis 9.9 ATP4A ATP12A
46 chronic intestinal vascular insufficiency 9.9 ATP4A ATP12A
47 barbiturate abuse 9.9 ATP4A ATP12A
48 duodenal gastrinoma 9.9 ATP4A ATP12A
49 gastric hemangioma 9.9 ATP4A ATP12A
50 blind loop syndrome 9.9 ATP4A ATP12A

Graphical network of the top 20 diseases related to Acquired Gastric Outlet Stenosis:



Diseases related to Acquired Gastric Outlet Stenosis

Symptoms & Phenotypes for Acquired Gastric Outlet Stenosis

MGI Mouse Phenotypes related to Acquired Gastric Outlet Stenosis:

46
# Description MGI Source Accession Score Top Affiliating Genes
1 digestive/alimentary MP:0005381 8.8 ATP12A ATP4A UCHL1

Drugs & Therapeutics for Acquired Gastric Outlet Stenosis

Search Clinical Trials , NIH Clinical Center for Acquired Gastric Outlet Stenosis

Genetic Tests for Acquired Gastric Outlet Stenosis

Anatomical Context for Acquired Gastric Outlet Stenosis

MalaCards organs/tissues related to Acquired Gastric Outlet Stenosis:

40
Cervix

Publications for Acquired Gastric Outlet Stenosis

Articles related to Acquired Gastric Outlet Stenosis:

(show all 25)
# Title Authors PMID Year
1
Adult hypertrophic pyloric stenosis that improved by spontaneous double channel pylorus formation. 61
33553675 2021
2
Focal pyloric hypertrophy in adults: a diagnostic pitfall-a case report and review of the literature. 61
31346979 2020
3
Endoscopic pyloroplasty for adult hypertrophic pyloric stenosis associated with esophageal achalasia. 61
29905182 2018
4
Video capsule endoscopy and CT enterography in diagnosing adult hypertrophic pyloric stenosis. 61
24115829 2013
5
Adult hypertrophic pyloric stenosis: case report and review. 61
9771452 1998
6
Primary hypertrophic pyloric stenosis in the adult. 61
1391735 1992
7
Multinodular adult hypertrophic pyloric stenosis. 61
2584668 1989
8
Adult hypertrophic pyloric stenosis: case report. 61
3775682 1986
9
Adult hypertrophic pyloric stenosis and gastric carcinoma. 61
3708291 1986
10
Sonographic diagnosis of adult hypertrophic pyloric stenosis. 61
3903210 1985
11
Adult hypertrophic pyloric stenosis--a description in 1834? 61
6350566 1983
12
Adult hypertrophic pyloric stenosis managed by double pyloroplasty. 61
7365976 1980
13
Adult hypertrophic pyloric stenosis. 61
464395 1979
14
Adult hypertrophic pyloric stenosis. Report of an unusual case detected by saline load test. 61
868847 1977
15
Adult hypertrophic pyloric stenosis and Crohn's disease. 61
1265022 1976
16
Adult hypertrophic pyloric stenosis. 61
4685929 1973
17
Adult hypertrophic pyloric stenosis described by G. B. Morgagni. 61
4940190 1971
18
The pyloric "cervix sign" in adult hypertrophic pyloric stenosis. 61
5426589 1970
19
Idiopathic adult hypertrophic pyloric stenosis. Non-operative diagnosis and management. 61
5798911 1969
20
Adult hypertrophic pyloric stenosis. 61
5822208 1969
21
Adult hypertrophic pyloric stenosis. Presentation of a case including cinégastroscopic findings. 61
5723699 1968
22
Primary adult hypertrophic pyloric stenosis. Case report and review of literature. 61
5651499 1968
23
The treatment of adult hypertrophic pyloric stenosis. 61
13985374 1963
24
Adult hypertrophic pyloric stenosis. Report of two cases with variable x-ray findings. 61
14419463 1959
25
Adult hypertrophic pyloric stenosis. 61
18912134 1948

Variations for Acquired Gastric Outlet Stenosis

Expression for Acquired Gastric Outlet Stenosis

Search GEO for disease gene expression data for Acquired Gastric Outlet Stenosis.

Pathways for Acquired Gastric Outlet Stenosis

GO Terms for Acquired Gastric Outlet Stenosis

Biological processes related to Acquired Gastric Outlet Stenosis according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 potassium ion transport GO:0006813 9.4 ATP4A ATP12A
2 proton transmembrane transport GO:1902600 9.37 ATP4A ATP12A
3 potassium ion import across plasma membrane GO:1990573 9.32 ATP4A ATP12A
4 cellular sodium ion homeostasis GO:0006883 9.26 ATP4A ATP12A
5 sodium ion export across plasma membrane GO:0036376 9.16 ATP4A ATP12A
6 cellular potassium ion homeostasis GO:0030007 8.96 ATP4A ATP12A
7 establishment or maintenance of transmembrane electrochemical gradient GO:0010248 8.62 ATP4A ATP12A

Molecular functions related to Acquired Gastric Outlet Stenosis according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 sodium:potassium-exchanging ATPase activity GO:0005391 9.16 ATP4A ATP12A
2 potassium-transporting ATPase activity GO:0008556 8.96 ATP4A ATP12A
3 potassium:proton exchanging ATPase activity GO:0008900 8.62 ATP4A ATP12A

Sources for Acquired Gastric Outlet Stenosis

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
17 EFO
18 ExPASy
19 FMA
20 GARD
28 GO
29 GTR
30 HMDB
31 HPO
32 ICD10
33 ICD10 via Orphanet
34 ICD9CM
35 IUPHAR
36 KEGG
37 LifeMap
39 LOVD
41 MedGen
44 MeSH
45 MESH via Orphanet
46 MGI
49 NCI
50 NCIt
51 NDF-RT
53 NINDS
54 Novoseek
56 OMIM via Orphanet
57 OMIM® (Updated 05-Mar-2021)
61 PubMed
63 QIAGEN
68 SNOMED-CT via HPO
69 TGDB
70 Tocris
71 UMLS
72 UMLS via Orphanet
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