MCID: ACQ004
MIFTS: 25

Acquired Hemangioma

Categories: Blood diseases, Cancer diseases, Cardiovascular diseases, Fetal diseases, Genetic diseases, Neuronal diseases, Rare diseases

Aliases & Classifications for Acquired Hemangioma

MalaCards integrated aliases for Acquired Hemangioma:

Name: Acquired Hemangioma 12 15 71

Classifications:



External Ids:

Disease Ontology 12 DOID:492
NCIt 49 C27018
UMLS 71 C0856897

Summaries for Acquired Hemangioma

MalaCards based summary : Acquired Hemangioma is related to capillary hemangioma and hemangioma. An important gene associated with Acquired Hemangioma is PROX1 (Prospero Homeobox 1), and among its related pathways/superpathways is Angiogenesis (CST). Affiliated tissues include breast, bone and brain, and related phenotypes are cardiovascular system and hematopoietic system

Related Diseases for Acquired Hemangioma

Diseases in the Hemangioma family:

Malignant Hemangioma Acquired Hemangioma
Familial Hemangioma Congenital Hemangioma

Diseases related to Acquired Hemangioma via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50) (show all 80)
# Related Disease Score Top Affiliating Genes
1 capillary hemangioma 28.5 VEGFA PROX1 PECAM1 PDPN LYVE1
2 hemangioma 28.1 VEGFA PROX1 PECAM1 PDPN LYVE1 F3
3 venous hemangioma 10.2 PROX1 PECAM1
4 kaposiform hemangioendothelioma 10.2 PROX1 PECAM1
5 auricular cancer 10.2 PDPN LYVE1
6 breast angiosarcoma 10.2 PROX1 PECAM1
7 conjunctival squamous cell carcinoma 10.2 PDPN LYVE1
8 angiokeratoma of fordyce 10.2 PROX1 PECAM1
9 cystic lymphangioma 10.2 PROX1 PECAM1
10 hobnail hemangioma 10.2 PECAM1 PDPN
11 stork bite 10.2 VEGFA PROX1
12 thrombophlebitis migrans 10.1 LYVE1 F3
13 prostate angiosarcoma 10.1 VEGFA PECAM1
14 pediatric angiosarcoma 10.1 VEGFA PECAM1
15 retroperitoneal hemangiopericytoma 10.1 VEGFA PECAM1
16 radiation proctitis 10.1 VEGFA PECAM1
17 proctitis 10.1 VEGFA PECAM1
18 glomeruloid hemangioma 10.1 VEGFA PECAM1
19 benign mesenchymoma 10.1 PECAM1 F3
20 angiokeratoma circumscriptum 10.1 VEGFA PECAM1
21 juvenile nasopharyngeal angiofibroma 10.1 VEGFA PECAM1
22 hydrocele 10.1 VEGFA PECAM1
23 intussusception 10.1 VEGFA PECAM1
24 pleural cancer 10.0 VEGFA PDPN
25 branch retinal artery occlusion 10.0 VEGFA F3
26 hantavirus pulmonary syndrome 10.0 VEGFA F3
27 angiodysplasia 10.0 VEGFA F3
28 hantavirus hemorrhagic fever with renal syndrome 10.0 VEGFA F3
29 papilledema 10.0 VEGFA F3
30 inflammatory breast carcinoma 10.0 PROX1 PDPN LYVE1
31 central retinal vein occlusion 10.0 VEGFA F3
32 retinal vein occlusion 10.0 VEGFA F3
33 pulmonary artery disease 10.0 VEGFA F3
34 corneal neovascularization 10.0 VEGFA PECAM1
35 hepatic vascular disease 10.0 VEGFA F3
36 blood protein disease 10.0 VEGFA F3
37 hepatic veno-occlusive disease 10.0 VEGFA F3
38 aspiration pneumonitis 10.0 OXT F3
39 keratitis, hereditary 10.0 VEGFA PECAM1
40 cavernous hemangioma 9.9 VEGFA PECAM1
41 mild pre-eclampsia 9.9 VEGFA OXT
42 nephrosclerosis 9.9 VEGFA F3
43 gorham's disease 9.9 PECAM1 PDPN LYVE1
44 lymphangitis 9.9 PECAM1 PDPN LYVE1
45 reticulum cell sarcoma 9.9 TNFRSF8 LYVE1
46 exanthem 9.9 VEGFA F3
47 persistent fetal circulation syndrome 9.9 VEGFA OXT
48 vein disease 9.9 VEGFA F3
49 uterine benign neoplasm 9.9 VEGFA OXT
50 arteriovenous malformations of the brain 9.9 VEGFA PECAM1

Graphical network of the top 20 diseases related to Acquired Hemangioma:



Diseases related to Acquired Hemangioma

Symptoms & Phenotypes for Acquired Hemangioma

MGI Mouse Phenotypes related to Acquired Hemangioma:

45
# Description MGI Source Accession Score Top Affiliating Genes
1 cardiovascular system MP:0005385 9.91 F3 LYVE1 OXT PDPN PECAM1 PROX1
2 hematopoietic system MP:0005397 9.8 F3 LYVE1 PDPN PECAM1 PROX1 TNFRSF8
3 digestive/alimentary MP:0005381 9.72 OXT PDPN PECAM1 PROX1 VEGFA
4 immune system MP:0005387 9.7 F3 LYVE1 PDPN PECAM1 PROX1 TNFRSF8
5 muscle MP:0005369 9.35 F3 PDPN PECAM1 PROX1 VEGFA
6 respiratory system MP:0005388 9.02 F3 PDPN PECAM1 PROX1 VEGFA

Drugs & Therapeutics for Acquired Hemangioma

Search Clinical Trials , NIH Clinical Center for Acquired Hemangioma

Genetic Tests for Acquired Hemangioma

Anatomical Context for Acquired Hemangioma

MalaCards organs/tissues related to Acquired Hemangioma:

40
Breast, Bone, Brain, Placenta, Prostate, T Cells

Publications for Acquired Hemangioma

Articles related to Acquired Hemangioma:

# Title Authors PMID Year
1
Acquired hemangioma with features of Dabska tum or: an additional case. 61
27804154 2017
2
Hemangioma with dabskoid features: a rare histopathologic variant of acquired hemangioma. 61
26347469 2016

Variations for Acquired Hemangioma

Expression for Acquired Hemangioma

Search GEO for disease gene expression data for Acquired Hemangioma.

Pathways for Acquired Hemangioma

Pathways related to Acquired Hemangioma according to GeneCards Suite gene sharing:

# Super pathways Score Top Affiliating Genes
1 10.87 PROX1 PECAM1 PDPN F3

GO Terms for Acquired Hemangioma

Cellular components related to Acquired Hemangioma according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 cell periphery GO:0071944 8.62 PECAM1 LYVE1

Biological processes related to Acquired Hemangioma according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 positive regulation of endothelial cell migration GO:0010595 9.4 VEGFA PROX1
2 positive regulation of positive chemotaxis GO:0050927 9.37 VEGFA F3
3 lung development GO:0030324 9.33 VEGFA PROX1 PDPN
4 lymphangiogenesis GO:0001946 9.32 PROX1 PDPN
5 positive regulation of cellular component movement GO:0051272 9.26 VEGFA PDPN
6 positive regulation of endothelial cell proliferation GO:0001938 9.13 VEGFA PROX1 F3
7 positive regulation of cell migration GO:0030335 8.92 VEGFA PECAM1 PDPN F3

Sources for Acquired Hemangioma

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
17 EFO
18 ExPASy
19 FMA
28 GO
29 GTR
30 HMDB
31 HPO
32 ICD10
33 ICD10 via Orphanet
34 ICD9CM
35 IUPHAR
36 KEGG
37 LifeMap
39 LOVD
41 MedGen
43 MeSH
44 MESH via Orphanet
45 MGI
48 NCI
49 NCIt
50 NDF-RT
53 NINDS
54 Novoseek
56 OMIM
57 OMIM via Orphanet
61 PubMed
63 QIAGEN
68 SNOMED-CT via HPO
69 TGDB
70 Tocris
71 UMLS
72 UMLS via Orphanet
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