MCID: ACQ039
MIFTS: 17

Acquired Purpura Fulminans

Categories: Blood diseases, Rare diseases, Skin diseases

Aliases & Classifications for Acquired Purpura Fulminans

MalaCards integrated aliases for Acquired Purpura Fulminans:

Name: Acquired Purpura Fulminans 58

Characteristics:

Orphanet epidemiological data:

58
acquired purpura fulminans
Inheritance: Not applicable; Age of onset: Infancy,Neonatal; Age of death: early childhood;

Classifications:

Orphanet: 58  
Rare haematological diseases


External Ids:

MESH via Orphanet 44 D014884 D055665
ICD10 via Orphanet 33 D65
UMLS via Orphanet 72 C0043068 C0085650
Orphanet 58 ORPHA49566

Summaries for Acquired Purpura Fulminans

MalaCards based summary : Acquired Purpura Fulminans is related to purpura fulminans and purpura. Affiliated tissues include skin, and related phenotypes are acrocyanosis and skin rash

Related Diseases for Acquired Purpura Fulminans

Diseases in the Purpura Fulminans family:

Acquired Purpura Fulminans

Diseases related to Acquired Purpura Fulminans via text searches within MalaCards or GeneCards Suite gene sharing:

# Related Disease Score Top Affiliating Genes
1 purpura fulminans 10.3
2 purpura 10.3
3 disseminated intravascular coagulation 10.2
4 alcohol dependence 10.0
5 exanthem 10.0
6 viral exanthem 10.0
7 meningococcemia 10.0

Graphical network of the top 20 diseases related to Acquired Purpura Fulminans:



Diseases related to Acquired Purpura Fulminans

Symptoms & Phenotypes for Acquired Purpura Fulminans

Human phenotypes related to Acquired Purpura Fulminans:

58 31 (show all 25)
# Description HPO Frequency Orphanet Frequency HPO Source Accession
1 acrocyanosis 58 31 frequent (33%) Frequent (79-30%) HP:0001063
2 skin rash 58 31 frequent (33%) Frequent (79-30%) HP:0000988
3 abnormal blistering of the skin 58 31 frequent (33%) Frequent (79-30%) HP:0008066
4 gangrene 58 31 frequent (33%) Frequent (79-30%) HP:0100758
5 thrombocytopenia 58 31 frequent (33%) Frequent (79-30%) HP:0001873
6 prolonged prothrombin time 58 31 frequent (33%) Frequent (79-30%) HP:0008151
7 decreased erythrocyte sedimentation rate 58 31 frequent (33%) Frequent (79-30%) HP:0025022
8 elevated c-reactive protein level 58 31 frequent (33%) Frequent (79-30%) HP:0011227
9 disseminated intravascular coagulation 58 31 frequent (33%) Frequent (79-30%) HP:0005521
10 erythematous macule 58 31 frequent (33%) Frequent (79-30%) HP:0025475
11 immune dysregulation 58 31 frequent (33%) Frequent (79-30%) HP:0002958
12 prolonged partial thromboplastin time 58 31 frequent (33%) Frequent (79-30%) HP:0003645
13 hypofibrinogenemia 58 31 frequent (33%) Frequent (79-30%) HP:0011900
14 reduced protein c activity 58 31 frequent (33%) Frequent (79-30%) HP:0005543
15 shock 58 31 frequent (33%) Frequent (79-30%) HP:0031273
16 reduced protein s activity 58 31 frequent (33%) Frequent (79-30%) HP:0004855
17 macular purpura 58 31 frequent (33%) Frequent (79-30%) HP:0031365
18 neoplasm 58 31 occasional (7.5%) Occasional (29-5%) HP:0002664
19 sepsis 58 31 occasional (7.5%) Occasional (29-5%) HP:0100806
20 intracranial hemorrhage 58 31 occasional (7.5%) Occasional (29-5%) HP:0002170
21 hepatic failure 58 31 occasional (7.5%) Occasional (29-5%) HP:0001399
22 pyoderma gangrenosum 58 31 very rare (1%) Very rare (<4-1%) HP:0025452
23 macule 58 Frequent (79-30%)
24 internal hemorrhage 58 Occasional (29-5%)
25 abnormal thrombosis 58 Frequent (79-30%)

Drugs & Therapeutics for Acquired Purpura Fulminans

Search Clinical Trials , NIH Clinical Center for Acquired Purpura Fulminans

Genetic Tests for Acquired Purpura Fulminans

Anatomical Context for Acquired Purpura Fulminans

MalaCards organs/tissues related to Acquired Purpura Fulminans:

40
Skin

Publications for Acquired Purpura Fulminans

Articles related to Acquired Purpura Fulminans:

# Title Authors PMID Year
1
Acquired purpura fulminans induced by alcohol and acetaminophen. Successful treatment with heparin and vitamin K. 61
8215490 1993
2
Rapid recovery of acquired purpura fulminans in a patient with familial C4bBP deficiency. 61
8486865 1993
3
Acquired purpura fulminans. 61
2281320 1990
4
Protein C and protein S levels in two patients with acquired purpura fulminans. 61
2142890 1990

Variations for Acquired Purpura Fulminans

Expression for Acquired Purpura Fulminans

Search GEO for disease gene expression data for Acquired Purpura Fulminans.

Pathways for Acquired Purpura Fulminans

GO Terms for Acquired Purpura Fulminans

Sources for Acquired Purpura Fulminans

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
17 EFO
18 ExPASy
19 FMA
28 GO
29 GTR
30 HMDB
31 HPO
32 ICD10
33 ICD10 via Orphanet
34 ICD9CM
35 IUPHAR
36 KEGG
37 LifeMap
39 LOVD
41 MedGen
43 MeSH
44 MESH via Orphanet
45 MGI
48 NCI
49 NCIt
50 NDF-RT
53 NINDS
54 Novoseek
56 OMIM
57 OMIM via Orphanet
61 PubMed
63 QIAGEN
68 SNOMED-CT via HPO
69 TGDB
70 Tocris
71 UMLS
72 UMLS via Orphanet
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