MCID: ACR097
MIFTS: 28

Acrodermatitis Chronica Atrophicans

Categories: Skin diseases

Aliases & Classifications for Acrodermatitis Chronica Atrophicans

MalaCards integrated aliases for Acrodermatitis Chronica Atrophicans:

Name: Acrodermatitis Chronica Atrophicans 12 15 17
Acrodermatitis Atrophicans Chronica 56 74
Primary Diffuse Atrophy 12
Herxheimer Disease 12

Classifications:



External Ids:

Disease Ontology 12 DOID:0060344
ICD9CM 36 701.8
ICD10 34 L90.4

Summaries for Acrodermatitis Chronica Atrophicans

Disease Ontology : 12 An acrodermatitis characterized by a chronically progressive course, leading to widespread atrophy of the skin. It is a clinical manifestation of Lyme borreliosis.

MalaCards based summary : Acrodermatitis Chronica Atrophicans, also known as acrodermatitis atrophicans chronica, is related to acrodermatitis and lyme disease. An important gene associated with Acrodermatitis Chronica Atrophicans is EPHA5 (EPH Receptor A5), and among its related pathways/superpathways are EphB-EphrinB Signaling and Tight junction. Affiliated tissues include skin and bone.

Wikipedia : 77 Acrodermatitis chronica atrophicans (ACA) is a skin rash indicative of the third or late stage of... more...

Related Diseases for Acrodermatitis Chronica Atrophicans

Diseases related to Acrodermatitis Chronica Atrophicans via text searches within MalaCards or GeneCards Suite gene sharing:

(show all 18)
# Related Disease Score Top Affiliating Genes
1 acrodermatitis 11.3
2 lyme disease 10.8
3 neuropathy 10.6
4 arthritis 10.5
5 peripheral nervous system disease 10.5
6 localized scleroderma 10.5
7 sarcoma 10.4
8 basal cell carcinoma 1 10.3
9 joint disorders 10.3
10 lymphoma 10.3
11 venous insufficiency 10.3
12 interstitial nephritis 10.3
13 squamous cell carcinoma 10.3
14 basal cell carcinoma 10.3
15 arthropathy 10.3
16 tenosynovitis 10.3
17 lichen sclerosus 10.3
18 multifocal motor neuropathy 9.7 CD1E CD40LG

Graphical network of the top 20 diseases related to Acrodermatitis Chronica Atrophicans:



Diseases related to Acrodermatitis Chronica Atrophicans

Symptoms & Phenotypes for Acrodermatitis Chronica Atrophicans

Drugs & Therapeutics for Acrodermatitis Chronica Atrophicans

Interventional clinical trials:


# Name Status NCT ID Phase Drugs
1 Borrelia Species in Cutaneous Lyme Borreliosis Recruiting NCT00576082

Search NIH Clinical Center for Acrodermatitis Chronica Atrophicans

Genetic Tests for Acrodermatitis Chronica Atrophicans

Anatomical Context for Acrodermatitis Chronica Atrophicans

MalaCards organs/tissues related to Acrodermatitis Chronica Atrophicans:

42
Skin, Bone

Publications for Acrodermatitis Chronica Atrophicans

Articles related to Acrodermatitis Chronica Atrophicans:

(show top 50) (show all 112)
# Title Authors Year
1
Asymetric red-blue hypertrophic hand and tenosynovitis due to acrodermatitis chronica atrophicans. ( 30239931 )
2019
2
Acrodermatitis chronica atrophicans in children: Report on two cases and review of the literature. ( 30389325 )
2019
3
Acrodermatitis chronica atrophicans: various faces of the late form of Lyme borreliosis. ( 30429707 )
2018
4
Correlation of Reflectance Confocal Microscopy and Dermatopathology Findings in a Case of Acrodermatitis Chronica Atrophicans. ( 29251638 )
2018
5
Pathogenetic implications of the age at time of diagnosis and skin location for acrodermatitis chronica atrophicans. ( 28017623 )
2017
6
Acrodermatitis Chronica Atrophicans. ( 26687575 )
2016
7
Expanding the clinicopathological spectrum of late cutaneous Lyme borreliosis (acrodermatitis chronica atrophicans [ACA]): A prospective study of 20 culture- and/or polymerase chain reaction (PCR)-documented cases. ( 26781226 )
2016
8
Asymmetric red-bluish foot due to acrodermatitis chronica atrophicans. ( 27335369 )
2016
9
A Souvenir From France: Acrodermatitis Chronica Atrophicans Presenting in the United States. ( 27502263 )
2016
10
Acrodermatitis chronica atrophicans-probably an overlooked differential diagnosis for arthritis. ( 27818388 )
2016
11
Fibrous nodules over the patella revealing acrodermatitis chronica atrophicans. ( 25048097 )
2015
12
Histopathology and immunophenotype of acrodermatitis chronica atrophicans correlated with ospA and ospC genotypes of Borrelia species. ( 26156537 )
2015
13
Acrodermatitis chronica atrophicans of the face: a case report and a brief review of the literature. ( 25230062 )
2014
14
Acrodermatitis chronica atrophicans with pseudolymphomatous infiltrates. ( 23147352 )
2013
15
Re: Andres C, et al. Acrodermatitis chronica atrophicans in two children. Int J Dermatol 2010; 49: 180-183. ( 23067095 )
2012
16
Isolation of Borrelia burgdorferi sensu lato from blood of adult patients with borrelial lymphocytoma, Lyme neuroborreliosis, Lyme arthritis and acrodermatitis chronica atrophicans. ( 21153429 )
2011
17
Acrodermatitis chronica atrophicans. ( 21958583 )
2011
18
Acrodermatitis chronica atrophicans in two children. ( 20465643 )
2010
19
Acrodermatitis chronica atrophicans: a case report and review of the literature. ( 20540415 )
2010
20
Skin-coloured facial oedema as an initial manifestation of acrodermatitis chronica atrophicans. ( 18482035 )
2008
21
Metastatic squamous cell carcinoma of the ankle in long-standing untreated acrodermatitis chronica atrophicans. ( 18607109 )
2008
22
Pick-Herxheimer's acrodermatitis chronica atrophicans in an endemic area of Northern Italy. ( 17184277 )
2006
23
Acrodermatitis chronica atrophicans in a 15-year-old girl misdiagnosed as venous insufficiency for 6 years. ( 15928636 )
2005
24
Two unusual cases of diffuse acrodermatitis chronica atrophicans seronegative for Lyme borreliosis. ( 12783283 )
2003
25
Acrodermatitis chronica atrophicans affecting all four limbs in an 11-year-old girl. ( 12174117 )
2002
26
Peripheral neuropathy in acrodermatitis chronica atrophicans - effect of treatment. ( 12371917 )
2002
27
Isolation of Borrelia burgdorferi sensu lato from a fibrous nodule in a patient with acrodermatitis chronica atrophicans. ( 12422596 )
2002
28
Differential expression of cytokine mRNA in skin specimens from patients with erythema migrans or acrodermatitis chronica atrophicans. ( 11121150 )
2000
29
Clinical features and specific immunological response to Borrelia afzelii in patients with acrodermatitis chronica atrophicans. ( 17312680 )
1999
30
Joint and bone involvement in Dutch patients with Lyme borreliosis presenting with acrodermatitis chronica atrophicans. ( 10048289 )
1999
31
Identification of three species of Borrelia burgdorferi sensu lato (B. burgdorferi sensu stricto, B. garinii, and B. afzelii) among isolates from acrodermatitis chronica atrophicans lesions. ( 9506437 )
1998
32
Jaccoud's arthropathy in acrodermatitis chronica atrophicans. ( 9566685 )
1998
33
Acrodermatitis chronica atrophicans: histopathologic findings and clinical correlations in 111 cases. ( 9602229 )
1998
34
Rheumatic manifestations related to acrodermatitis chronica atrophicans. A review of four cases. ( 9809360 )
1998
35
Acrodermatitis chronica atrophicans and serologic confirmation of infection due to Borrelia afzelii and/or Borrelia garinii by immunoblot. ( 11864312 )
1998
36
Long-term prognosis in patients treated for erythema chronicum migrans and acrodermatitis chronica atrophicans. ( 9006370 )
1997
37
Peripheral neuropathy in acrodermatitis chronica atrophicans - a late Borrelia manifestation. ( 9228267 )
1997
38
Detection of Borrelia afzelii, Borrelia burgdorferi sensu stricto, Borrelia garinii and group VS116 by PCR in skin biopsies of patients with erythema migrans and acrodermatitis chronica atrophicans. ( 11864084 )
1997
39
Etiology of the acrodermatitis chronica atrophicans lesion in Lyme disease. ( 8699080 )
1996
40
Acrodermatitis chronica atrophicans in an Italian child. ( 8800311 )
1996
41
Success and failure in the treatment of acrodermatitis chronica atrophicans. ( 8852478 )
1996
42
Acrodermatitis chronica atrophicans in an 11-year-old girl. ( 8915157 )
1996
43
Identification of Borrelia afzelii in a juxta-articular fibroid nodule from a human immunodeficiency virus-positive patient with acrodermatitis chronica atrophicans. ( 7503587 )
1995
44
Acrodermatitis chronica atrophicans: a light and electron microscopic study. ( 7751475 )
1995
45
Lymphoproliferative responses to Borrelia burgdorferi in patients with erythema migrans, acrodermatitis chronica atrophicans, lymphadenosis benigna cutis, and morphea. ( 7778918 )
1995
46
Detection of Borrelia burgdorferi sensu lato in lesional skin of patients with erythema migrans and acrodermatitis chronica atrophicans by ospA-specific PCR. ( 7883886 )
1994
47
Changes in Borrelia burgdorferi-specific serum IgG antibody levels in patients treated for acrodermatitis chronica atrophicans. ( 7701871 )
1994
48
Acrodermatitis chronica atrophicans involving the face. Evidence for Borrelia burgdorferi infection confirmed by DNA amplification. ( 7873838 )
1994
49
Serological follow-up after treatment of Borrelia arthritis and acrodermatitis chronica atrophicans. ( 7939435 )
1994
50
Acrodermatitis chronica atrophicans in the United States: clinical and histopathologic features of six cases. ( 7956339 )
1994

Variations for Acrodermatitis Chronica Atrophicans

Expression for Acrodermatitis Chronica Atrophicans

Search GEO for disease gene expression data for Acrodermatitis Chronica Atrophicans.

Pathways for Acrodermatitis Chronica Atrophicans

Pathways related to Acrodermatitis Chronica Atrophicans according to GeneCards Suite gene sharing:

# Super pathways Score Top Affiliating Genes
1
Show member pathways
11.34 AFDN EPHA5
2 10.85 AFDN CD1E

GO Terms for Acrodermatitis Chronica Atrophicans

Cellular components related to Acrodermatitis Chronica Atrophicans according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 adherens junction GO:0005912 8.62 AFDN EPHA5

Sources for Acrodermatitis Chronica Atrophicans

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
17 EFO
18 ExPASy
20 FMA
29 GO
30 GTR
31 HGMD
32 HMDB
33 HPO
34 ICD10
35 ICD10 via Orphanet
36 ICD9CM
37 IUPHAR
38 KEGG
39 LifeMap
41 LOVD
43 MedGen
45 MeSH
46 MESH via Orphanet
47 MGI
50 NCI
51 NCIt
52 NDF-RT
55 NINDS
56 Novoseek
58 OMIM
59 OMIM via Orphanet
63 PubMed
65 QIAGEN
70 SNOMED-CT via HPO
71 SNOMED-CT via Orphanet
72 TGDB
73 Tocris
74 UMLS
75 UMLS via Orphanet
Content
Loading form....