MCID: ACT046
MIFTS: 25

Acute Apical Periodontitis

Categories: Gastrointestinal diseases, Oral diseases

Aliases & Classifications for Acute Apical Periodontitis

MalaCards integrated aliases for Acute Apical Periodontitis:

Name: Acute Apical Periodontitis 12 15
Acute Apical Periodontitis of Pulpal Origin 12 71 32

Classifications:



External Ids:

Disease Ontology 12 DOID:11693
ICD9CM 34 522.4
SNOMED-CT 67 88071000
ICD10 32 K04.4
UMLS 71 C0155934

Summaries for Acute Apical Periodontitis

MalaCards based summary : Acute Apical Periodontitis, also known as acute apical periodontitis of pulpal origin, is related to periodontitis and candida glabrata. An important gene associated with Acute Apical Periodontitis is VEZF1 (Vascular Endothelial Zinc Finger 1), and among its related pathways/superpathways is Salivary secretion.

Related Diseases for Acute Apical Periodontitis

Diseases in the Acute Apical Periodontitis family:

Chronic Apical Periodontitis

Diseases related to Acute Apical Periodontitis via text searches within MalaCards or GeneCards Suite gene sharing:

(show all 44)
# Related Disease Score Top Affiliating Genes
1 periodontitis 10.6
2 candida glabrata 10.3 HTN3 HTN1
3 root caries 10.3 STATH CST4
4 hypertensive retinopathy 10.1 VEZF1 ACE
5 angiokeratoma of fordyce 10.1 NKRF ACE
6 renal artery obstruction 10.0 HTN3 HTN1 ACE
7 orbital disease 10.0 TG ACE
8 hereditary angioedema with normal c1inh 10.0 KNG1 ACE
9 diffuse scleroderma 10.0 KNG1 ACE
10 dental caries 10.0 STATH HTN3 HTN1 BMP2
11 oxirane allergy 10.0 KNG1 IL3
12 autosomal recessive hypophosphatemic rickets 10.0 STATH PHEX
13 dens evaginatus 10.0
14 pulpitis 10.0
15 phenytoin allergy 9.9 KNG1 IL3
16 endometrial small cell carcinoma 9.9 TG TAC1
17 coronary artery vasospasm 9.9 KNG1 ACE
18 perianal hematoma 9.9 TAC1 KNG1
19 interval angle-closure glaucoma 9.9 TAC1 KNG1
20 algoneurodystrophy 9.9 TAC1 KNG1
21 osseous heteroplasia, progressive 9.9 KNG1 BMP2 ACE
22 myofascial pain syndrome 9.9 TAC1 KNG1
23 reflex sympathetic dystrophy 9.9 TAC1 KNG1
24 ulnar nerve lesion 9.9 TAC1 BMP2
25 bursitis 9.9 TAC1 KNG1
26 myocardial stunning 9.9 KNG1 ACE
27 bladder neck obstruction 9.8 TAC1 ACE
28 dental pulp disease 9.8 TAC1 BMP2
29 vasomotor rhinitis 9.8 TAC1 KNG1
30 spondylolisthesis 9.8 TAC1 BMP2
31 facial dermatosis 9.8 TAC1 CTRL
32 chronic urticaria 9.8 TG IL3 ACE
33 trigeminal nerve disease 9.8 TAC1 KNG1
34 trigeminal neuralgia 9.7 TAC1 KNG1
35 serotonin syndrome 9.7 TAC1 CYP2D6
36 bone disease 9.6 PHEX KNG1 IL3 BMP2
37 intracranial vasospasm 9.6 TAC1 KNG1 ACE
38 akinetopsia 9.6 TAC1 KNG1 CYP2D6
39 pain agnosia 9.6 TAC1 KNG1 CYP2D6
40 agnosia 9.6 TAC1 KNG1 CYP2D6
41 aspiration pneumonia 9.5 TAC1 ACE
42 migraine with or without aura 1 9.3 TAC1 KNG1 CYP2D6 ACE
43 hypertension, essential 9.1 TAC1 KNG1 HTN3 HTN1 CYP2D6 ACE
44 disease of mental health 8.4 TG TAC1 KNG1 IL3 CYP2D6 CTRL

Comorbidity relations with Acute Apical Periodontitis via Phenotypic Disease Network (PDN):


Dental Caries Heart Disease

Graphical network of the top 20 diseases related to Acute Apical Periodontitis:



Diseases related to Acute Apical Periodontitis

Symptoms & Phenotypes for Acute Apical Periodontitis

Drugs & Therapeutics for Acute Apical Periodontitis

Search Clinical Trials , NIH Clinical Center for Acute Apical Periodontitis

Genetic Tests for Acute Apical Periodontitis

Anatomical Context for Acute Apical Periodontitis

Publications for Acute Apical Periodontitis

Articles related to Acute Apical Periodontitis:

(show top 50) (show all 88)
# Title Authors PMID Year
1
Evaluation of the knowledge of final-year dental students on the use of antibiotics in endodontics in Turkey. 61
33410573 2021
2
Management of odonto-stomatological emergencies during the COVID-19 alarm state in dental clinics in the Autonomous Community of Madrid (CAM), Spain: An observational study. 61
33037804 2021
3
Tooth autotransplantation using an interdisciplinary approach to rehabilitation in a young patient: case report with 7-year follow-up. 61
33269534 2020
4
Impact of COVID-19 on Dental Emergency Services in Cluj-Napoca Metropolitan Area: A Cross-Sectional Study. 61
33105688 2020
5
Fluid transport from the dental pulp revisited. 61
32794278 2020
6
Antibiotic Administration Along with Endodontic Therapy in the Republic of Croatia: a Pilot Study. 61
33132394 2020
7
Comparison Of Two Intra-Canal Medicaments On The Incidence Of Post-Operative Endodontic Pain. 61
32829540 2020
8
Macrophage migration inhibitory factor gene polymorphisms as exacerbating factors of apical periodontitis. 61
32427427 2020
9
Prescription of antibiotics for pulpal and periapical pathology among dentists in southern Saudi Arabia. 61
28455077 2017
10
[Mathematical-cartographic modeling and forecasting of caries and acute apical periodontitis incidence in pediatric population]. 61
29260766 2017
11
Emergency care provided in a Greek dental school and analysis of the patients' demographic characteristics: a prospective study. 61
27302884 2016
12
Assessment of pain among a group of Nigerian dental patients. 61
26087661 2015
13
The Attitudes of Dentists Towards the Prescription of Antibiotics During Endodontic Treatment in North of Saudi Arabia. 61
26155570 2015
14
Revascularization of an immature tooth with apical periodontitis using a single visit protocol: a case report. 61
25066513 2015
15
A self-administered method of acute pressure block of sciatic nerves for short-term relief of dental pain: a randomized study. 61
24400593 2014
16
Knowledge and Pattern of Antibiotic and Non Narcotic Analgesic Prescription for Pulpal and Periapical Pathologies- A Survey among Dentists. 61
25177628 2014
17
Antibiotic prescription pattern among Indian oral healthcare providers: a cross-sectional survey. 61
24080499 2014
18
[Pulp revascularization of immature teeth with apical periodontitis: a clinical study]. 61
23714059 2013
19
Acute apical periodontitis and vertical root fracture of the same tooth: a case report. 61
23748460 2013
20
Intracanal medications versus placebo in reducing postoperative endodontic pain--a double-blind randomized clinical trial. 61
23657409 2013
21
Antibiotic prescribing habits of dental surgeons in hyderabad city, India, for pulpal and periapical pathologies: a survey. 61
24187549 2013
22
Treatment approaches and antibiotic use for emergency dental treatment in Turkey. 61
24307834 2013
23
Symptomatic and asymptomatic apical periodontitis associated with red complex bacteria: clinical and microbiological evaluation. 61
22143381 2013
24
Melanin pigmented periradicular lesions of extracted teeth: a report of 3 cases and review of the literature. 61
22428524 2011
25
Periapical granuloma associated with extracted teeth. 61
22037071 2011
26
Revascularization of an immature permanent tooth with periradicular abscess after luxation. 61
21244629 2011
27
Comparison of 2% chlorhexidine and 5.25% sodium hypochlorite irrigating solutions on postoperative pain: a randomized clinical trial. 61
21187618 2010
28
Pattern of antibiotic prescription in the management of endodontic infections amongst Spanish oral surgeons. 61
20487455 2010
29
Prevalence of new candidate pathogens Prevotella baroniae, Prevotella multisaccharivorax and as-yet-uncultivated Bacteroidetes clone X083 in primary endodontic infections. 61
19801230 2009
30
Antibiotic use by members of the Spanish Endodontic Society. 61
19720216 2009
31
Pain associated with root canal treatment. 61
19467050 2009
32
Pulp revascularization of immature teeth with apical periodontitis: a clinical study. 61
19410097 2009
33
Loss of pulp sensitivity and pain as the first symptoms of a Ewing's sarcoma in the right maxillary sinus and alveolar process: report of a case. 61
19026893 2008
34
Prevalence and clonal analysis of Porphyromonas gingivalis in primary endodontic infections. 61
18928841 2008
35
Dry socket: a prospective study of prevalent risk factors in a Nigerian population. 61
18940494 2008
36
Isolation and identification of Enterococcus faecalis from necrotic root canals using multiplex PCR. 61
17928729 2007
37
Preoperative pain and medications used in emergency patients with irreversible acute pulpitis or acute apical periodontitis: a prospective comparative study. 61
18018991 2007
38
Catonella morbi and Granulicatella adiacens: new species in endodontic infections. 61
16876072 2006
39
Influence of the length of instrumentation and canal obturation on the success of endodontic therapy. A 10-year clinical follow-up. 61
16939025 2006
40
Culture-independent detection of Eikenella corrodens and Veillonella parvula in primary endodontic infections. 61
16728238 2006
41
Occurrence of two newly named oral treponemes - Treponema parvum and Treponema putidum - in primary endodontic infections. 61
16238598 2005
42
Detection of bacteria in endodontic samples by polymerase chain reaction assays and association with defined clinical signs in Italian patients. 61
16101964 2005
43
[Stomatologic diseases in young men with constitutionally related malnutrition]. 61
15690851 2004
44
Association of Enterococcus faecalis with different forms of periradicular diseases. 61
15107642 2004
45
Nested PCR detection of Centipeda periodontii in primary endodontic infections. 61
15055428 2004
46
Clinical practice guideline on emergency management of acute apical periodontitis (AAP) in adults. 61
15238966 2004
47
Clinical practice guidelines on emergency management of acute apical periodontitis and acute apical abscess. Evidence-based Dentistry 2004;5:7-11. 61
15448658 2004
48
Bacterial infections of pulp and periodontal origin. 61
15580135 2004
49
The relationship of intracanal medicaments to postoperative pain in endodontics. 61
14641427 2003
50
Pseudoramibacter alactolyticus in primary endodontic infections. 61
14651280 2003

Variations for Acute Apical Periodontitis

Expression for Acute Apical Periodontitis

Search GEO for disease gene expression data for Acute Apical Periodontitis.

Pathways for Acute Apical Periodontitis

Pathways related to Acute Apical Periodontitis according to GeneCards Suite gene sharing:

# Super pathways Score Top Affiliating Genes
1
Show member pathways
11.45 STATH HTN3 HTN1 CTRL CST4

GO Terms for Acute Apical Periodontitis

Cellular components related to Acute Apical Periodontitis according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 extracellular space GO:0005615 9.61 TG TAC1 MIF KNG1 IL3 CTRL
2 extracellular region GO:0005576 9.36 TG TAC1 STATH MIF KNG1 IL3

Biological processes related to Acute Apical Periodontitis according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 inflammatory response GO:0006954 9.56 TAC1 MIF KNG1 BMP2
2 defense response to fungus GO:0050832 9.37 HTN3 HTN1
3 negative regulation of proteolysis GO:0045861 9.32 KNG1 CST4
4 cell-cell signaling GO:0007267 9.26 TAC1 PHEX IL3 BMP2
5 positive regulation of ossification GO:0045778 9.16 TAC1 BMP2
6 biomineral tissue development GO:0031214 8.92 STATH PHEX HTN3 HTN1

Sources for Acute Apical Periodontitis

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
17 EFO
18 ExPASy
19 FMA
20 GARD
28 GO
29 GTR
30 HMDB
31 HPO
32 ICD10
33 ICD10 via Orphanet
34 ICD9CM
35 IUPHAR
36 KEGG
37 LifeMap
39 LOVD
41 MedGen
44 MeSH
45 MESH via Orphanet
46 MGI
49 NCI
50 NCIt
51 NDF-RT
53 NINDS
54 Novoseek
56 OMIM via Orphanet
57 OMIM® (Updated 05-Mar-2021)
61 PubMed
63 QIAGEN
68 SNOMED-CT via HPO
69 TGDB
70 Tocris
71 UMLS
72 UMLS via Orphanet
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