MCID: ACT046
MIFTS: 18

Acute Apical Periodontitis

Categories: Gastrointestinal diseases, Oral diseases

Aliases & Classifications for Acute Apical Periodontitis

MalaCards integrated aliases for Acute Apical Periodontitis:

Name: Acute Apical Periodontitis 12 15
Acute Apical Periodontitis of Pulpal Origin 12 73

Classifications:



External Ids:

Disease Ontology 12 DOID:11693
ICD10 33 K04.4
ICD9CM 35 522.4
UMLS 73 C0155934

Summaries for Acute Apical Periodontitis

MalaCards based summary : Acute Apical Periodontitis, also known as acute apical periodontitis of pulpal origin, is related to periodontitis and pulpitis. An important gene associated with Acute Apical Periodontitis is TSPAN7 (Tetraspanin 7). The drugs Clindamycin and Amoxicillin have been mentioned in the context of this disorder.

Related Diseases for Acute Apical Periodontitis

Diseases in the Acute Apical Periodontitis family:

Chronic Apical Periodontitis

Diseases related to Acute Apical Periodontitis via text searches within MalaCards or GeneCards Suite gene sharing:

# Related Disease Score Top Affiliating Genes
1 periodontitis 10.3
2 pulpitis 9.8

Comorbidity relations with Acute Apical Periodontitis via Phenotypic Disease Network (PDN):


Dental Caries Heart Disease
Ischemic Heart Disease

Symptoms & Phenotypes for Acute Apical Periodontitis

Drugs & Therapeutics for Acute Apical Periodontitis

Drugs for Acute Apical Periodontitis (from DrugBank, HMDB, Dgidb, PharmGKB, IUPHAR, NovoSeek, BitterDB):

(show all 9)
# Name Status Phase Clinical Trials Cas Number PubChem Id
1
Clindamycin Approved, Vet_approved Phase 2, Phase 3 18323-44-9 29029
2
Amoxicillin Approved, Vet_approved Phase 2, Phase 3,Not Applicable 26787-78-0 33613
3 Anti-Bacterial Agents Phase 2, Phase 3,Phase 3,Not Applicable
4 Anti-Infective Agents Phase 2, Phase 3,Phase 3,Not Applicable
5 Clindamycin palmitate Phase 2, Phase 3
6 Clindamycin phosphate Phase 2, Phase 3
7 Amoxicillin-Potassium Clavulanate Combination Phase 2, Phase 3,Not Applicable
8 beta-Lactamase Inhibitors Phase 2, Phase 3,Not Applicable
9 Clavulanic Acid Phase 2, Phase 3,Not Applicable

Interventional clinical trials:


# Name Status NCT ID Phase Drugs
1 Effect of Preoperative Clindamycin on Postoperative Endodontic Pain Not yet recruiting NCT03033472 Phase 2, Phase 3 600 mg Clindamycin orally;Oral Placebo
2 Effect of Preoperative Amoxicillin/Clavulanic Acid Combination on Postoperative Endodontic Pain Not yet recruiting NCT03033147 Phase 2, Phase 3 Amoxicillin/Clavulanate Potassium 875 mg-125 mg oral tablet;Oral placebo
3 The Effect of Central Sensitization on Assessment Capacity of Patients Completed NCT03553641
4 Effect of Amoxicillin/Clavulanic Acid Combination on Postoperative Endodontic Pain Not yet recruiting NCT03007342 Not Applicable Amoxicillin/Clavulanate Potassium 875 mg-125 mg oral tablet;Placebo

Search NIH Clinical Center for Acute Apical Periodontitis

Genetic Tests for Acute Apical Periodontitis

Anatomical Context for Acute Apical Periodontitis

Publications for Acute Apical Periodontitis

Articles related to Acute Apical Periodontitis:

# Title Authors Year
1
Acute apical periodontitis and vertical root fracture of the same tooth: a case report. ( 23748460 )
2013
2
Preoperative pain and medications used in emergency patients with irreversible acute pulpitis or acute apical periodontitis: a prospective comparative study. ( 18018991 )
2007
3
Clinical practice guideline on emergency management of acute apical periodontitis (AAP) in adults. ( 15238966 )
2004
4
Clinical practice guidelines on emergency management of acute apical periodontitis and acute apical abscess. Evidence-based Dentistry 2004;5:7-11. ( 15448658 )
2004
5
Talon cusp causing occlusal trauma and acute apical periodontitis: report of a case. ( 12656857 )
2003
6
Emergency management of acute apical periodontitis in the permanent dentition: a systematic review of the literature. ( 12622880 )
2003
7
A comparison of ketorolac tromethamine and acetaminophen codeine in the management of acute apical periodontitis. ( 10425951 )
1999
8
Acute apical periodontitis: incidence of post-operative pain using two different root canal dressings. ( 9823137 )
1998
9
Corticosteroid use in acute apical periodontitis: a review with clinical implications. ( 3078589 )
1988
10
Remission of pain of acute apical periodontitis after blockage of apex with filings: case report. ( 1062494 )
1976

Variations for Acute Apical Periodontitis

Expression for Acute Apical Periodontitis

Search GEO for disease gene expression data for Acute Apical Periodontitis.

Pathways for Acute Apical Periodontitis

GO Terms for Acute Apical Periodontitis

Sources for Acute Apical Periodontitis

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
17 ExPASy
19 FMA
28 GO
29 GTR
30 HGMD
31 HMDB
32 HPO
33 ICD10
34 ICD10 via Orphanet
35 ICD9CM
36 IUPHAR
37 KEGG
38 LifeMap
40 LOVD
42 MedGen
44 MeSH
45 MESH via Orphanet
46 MGI
49 NCI
50 NCIt
51 NDF-RT
54 NINDS
55 Novoseek
57 OMIM
58 OMIM via Orphanet
62 PubMed
64 QIAGEN
69 SNOMED-CT via HPO
70 SNOMED-CT via Orphanet
71 TGDB
72 Tocris
73 UMLS
74 UMLS via Orphanet
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