MCID: ACT046
MIFTS: 15

Acute Apical Periodontitis

Categories: Gastrointestinal diseases, Oral diseases

Aliases & Classifications for Acute Apical Periodontitis

MalaCards integrated aliases for Acute Apical Periodontitis:

Name: Acute Apical Periodontitis 12
Acute Apical Periodontitis of Pulpal Origin 12 74

Classifications:



External Ids:

Disease Ontology 12 DOID:11693
ICD9CM 36 522.4
SNOMED-CT 69 88071000
ICD10 34 K04.4
UMLS 74 C0155934

Summaries for Acute Apical Periodontitis

MalaCards based summary : Acute Apical Periodontitis, also known as acute apical periodontitis of pulpal origin, is related to periapical periodontitis and periodontitis. The drugs Clindamycin and Amoxicillin have been mentioned in the context of this disorder.

Related Diseases for Acute Apical Periodontitis

Diseases in the Acute Apical Periodontitis family:

Chronic Apical Periodontitis

Diseases related to Acute Apical Periodontitis via text searches within MalaCards or GeneCards Suite gene sharing:

# Related Disease Score Top Affiliating Genes
1 periapical periodontitis 10.4
2 periodontitis 10.4
3 pulpitis 9.9

Comorbidity relations with Acute Apical Periodontitis via Phenotypic Disease Network (PDN):


Dental Caries Heart Disease
Ischemic Heart Disease

Symptoms & Phenotypes for Acute Apical Periodontitis

Drugs & Therapeutics for Acute Apical Periodontitis

Drugs for Acute Apical Periodontitis (from DrugBank, HMDB, Dgidb, PharmGKB, IUPHAR, NovoSeek, BitterDB):

(show all 9)
# Name Status Phase Clinical Trials Cas Number PubChem Id
1
Clindamycin Approved, Vet_approved Phase 2, Phase 3 18323-44-9 29029
2
Amoxicillin Approved, Vet_approved Phase 2, Phase 3,Not Applicable 26787-78-0 33613
3 Anti-Infective Agents Phase 2, Phase 3,Phase 3,Not Applicable
4 Clindamycin phosphate Phase 2, Phase 3
5 Anti-Bacterial Agents Phase 2, Phase 3,Phase 3,Not Applicable
6 Clindamycin palmitate Phase 2, Phase 3
7 beta-Lactamase Inhibitors Phase 2, Phase 3,Not Applicable
8 Clavulanic Acids Phase 2, Phase 3,Not Applicable
9 Amoxicillin-Potassium Clavulanate Combination Phase 2, Phase 3,Not Applicable

Interventional clinical trials:


# Name Status NCT ID Phase Drugs
1 Effect of Preoperative Clindamycin on Postoperative Endodontic Pain Unknown status NCT03033472 Phase 2, Phase 3 600 mg Clindamycin orally;Oral Placebo
2 Effect of Preoperative Amoxicillin/Clavulanic Acid Combination on Postoperative Endodontic Pain Unknown status NCT03033147 Phase 2, Phase 3 Amoxicillin/Clavulanate Potassium 875 mg-125 mg oral tablet;Oral placebo
3 Effect of Amoxicillin/Clavulanic Acid Combination on Postoperative Endodontic Pain Unknown status NCT03007342 Not Applicable Amoxicillin/Clavulanate Potassium 875 mg-125 mg oral tablet;Placebo
4 The Effect of Central Sensitization on Assessment Capacity of Patients Completed NCT03553641

Search NIH Clinical Center for Acute Apical Periodontitis

Genetic Tests for Acute Apical Periodontitis

Anatomical Context for Acute Apical Periodontitis

Publications for Acute Apical Periodontitis

Articles related to Acute Apical Periodontitis:

# Title Authors Year
1
Acute apical periodontitis and vertical root fracture of the same tooth: a case report. ( 23748460 )
2013
2
Preoperative pain and medications used in emergency patients with irreversible acute pulpitis or acute apical periodontitis: a prospective comparative study. ( 18018991 )
2007
3
Clinical practice guideline on emergency management of acute apical periodontitis (AAP) in adults. ( 15238966 )
2004
4
Clinical practice guidelines on emergency management of acute apical periodontitis and acute apical abscess. Evidence-based Dentistry 2004;5:7-11. ( 15448658 )
2004
5
Emergency management of acute apical periodontitis in the permanent dentition: a systematic review of the literature. ( 12622880 )
2003
6
Talon cusp causing occlusal trauma and acute apical periodontitis: report of a case. ( 12656857 )
2003
7
A comparison of ketorolac tromethamine and acetaminophen codeine in the management of acute apical periodontitis. ( 10425951 )
1999
8
Acute apical periodontitis: incidence of post-operative pain using two different root canal dressings. ( 9823137 )
1998
9
Corticosteroid use in acute apical periodontitis: a review with clinical implications. ( 3078589 )
1988
10
Remission of pain of acute apical periodontitis after blockage of apex with filings: case report. ( 1062494 )
1976

Variations for Acute Apical Periodontitis

Expression for Acute Apical Periodontitis

Search GEO for disease gene expression data for Acute Apical Periodontitis.

Pathways for Acute Apical Periodontitis

GO Terms for Acute Apical Periodontitis

Sources for Acute Apical Periodontitis

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
17 EFO
18 ExPASy
20 FMA
29 GO
30 GTR
31 HGMD
32 HMDB
33 HPO
34 ICD10
35 ICD10 via Orphanet
36 ICD9CM
37 IUPHAR
38 KEGG
39 LifeMap
41 LOVD
43 MedGen
45 MeSH
46 MESH via Orphanet
47 MGI
50 NCI
51 NCIt
52 NDF-RT
55 NINDS
56 Novoseek
58 OMIM
59 OMIM via Orphanet
63 PubMed
65 QIAGEN
70 SNOMED-CT via HPO
71 SNOMED-CT via Orphanet
72 TGDB
73 Tocris
74 UMLS
75 UMLS via Orphanet
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