MCID: ACT066
MIFTS: 33

Acute Cervicitis

Categories: Reproductive diseases

Aliases & Classifications for Acute Cervicitis

MalaCards integrated aliases for Acute Cervicitis:

Name: Acute Cervicitis 12 15 73

Classifications:



External Ids:

Disease Ontology 12 DOID:10616
NCIt 50 C27056
SNOMED-CT 68 19272000
UMLS 73 C0269061

Summaries for Acute Cervicitis

MalaCards based summary : Acute Cervicitis is related to neurosyphilis and spotted fever. An important gene associated with Acute Cervicitis is SERPIND1 (Serpin Family D Member 1), and among its related pathways/superpathways are Innate Immune System and PEDF Induced Signaling. Affiliated tissues include spinal cord, and related phenotypes are Decreased viability and Decreased viability

Related Diseases for Acute Cervicitis

Diseases in the Cervicitis family:

Acute Cervicitis Chronic Cervicitis

Diseases related to Acute Cervicitis via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50) (show all 96)
# Related Disease Score Top Affiliating Genes
1 neurosyphilis 10.6 CXCL10 TLR2
2 spotted fever 10.5 CCL5 CXCL10
3 prosthetic joint infection 10.4 TLR2 TLR4
4 japanese encephalitis 10.4 CCL5 CXCL10
5 trench fever 10.4 TLR2 TLR4
6 genital herpes 10.4 CCL5 TLR2
7 suppurative otitis media 10.4 TLR2 TLR4
8 alveolar echinococcosis 10.4 TLR2 TLR4
9 neisseria meningitidis infection 10.4 TLR2 TLR4
10 septic arthritis 10.3 TLR2 TLR4
11 viral meningitis 10.3 CCL5 CXCL10
12 scrub typhus 10.3 TLR2 TLR4
13 middle ear disease 10.3 TLR2 TLR4
14 irak4 deficiency 10.3 TLR2 TLR4
15 cervicitis 10.3
16 myd88 deficiency 10.3 TLR2 TLR4
17 sarcoidosis 1 10.2 CCL5 CXCL10 CXCL5
18 q fever 10.2 TLR2 TLR4
19 viral encephalitis 10.2 CCL5 CXCL10
20 pelvic inflammatory disease 10.1 TLR2 TLR4
21 invasive aspergillosis 10.1 CXCL10 TLR2 TLR4
22 lymphoproliferative syndrome 2 10.1 CD276 CXCL10
23 penicilliosis 10.1 CD86 TLR2 TLR4
24 primary bacterial infectious disease 10.1 CXCL10 TLR2 TLR4
25 myositis fibrosa 10.1 CD86 TLR2 TLR4
26 pulmonary disease, chronic obstructive 10.1 CCL5 CXCL10 TLR2
27 mycobacterium tuberculosis 1 10.1 CXCL10 TLR2 TLR4
28 eosinophilic pneumonia 10.0 CCL5 CSF2
29 japanese spotted fever 10.0 CCL4 CXCL10
30 omsk hemorrhagic fever 10.0 CCL4 CCL5
31 pulmonary sarcoidosis 10.0 CCL5 CSF2 CXCL5
32 filariasis 10.0 CCL5 TLR2 TLR4
33 idiopathic neutropenia 10.0 CCL5 TLR4
34 bacterial vaginosis 10.0 TLR2 TLR4
35 whiplash 10.0 CCL4 CCL5
36 spinal cord injury 9.9
37 mastitis 9.9 CCL5 CSF2 TLR2
38 stachybotrys chartarum 9.9 CCL4 CCL5
39 chronic nk-cell lymphocytosis 9.9 CCL4 CCL5
40 ileitis 9.9 CSF2 TLR2 TLR4
41 keratitis, hereditary 9.9 CXCL1 TLR2 TLR4
42 legionellosis 9.8 TLR2 TLR4
43 lung disease 9.8 CCL5 CSF2 TLR2
44 dermatitis, atopic 9.8 CCL5 CSF2 TLR2
45 helicobacter pylori infection 9.8 CCL5 CXCL1 TLR4
46 respiratory system disease 9.8 CCL5 CSF2 TLR4
47 carotid artery occlusion 9.7
48 paracoccidioidomycosis 9.7 CD86 CXCL10 TLR2 TLR4
49 cervical dystonia 9.7
50 radiculopathy 9.7

Graphical network of the top 20 diseases related to Acute Cervicitis:



Diseases related to Acute Cervicitis

Symptoms & Phenotypes for Acute Cervicitis

GenomeRNAi Phenotypes related to Acute Cervicitis according to GeneCards Suite gene sharing:

26
# Description GenomeRNAi Source Accession Score Top Affiliating Genes
1 Decreased viability GR00231-A 9.02 CCL4 CXCL10
2 Decreased viability GR00342-S-3 9.02 CCL4
3 Decreased viability GR00402-S-2 9.02 CCL4 CXCL10

MGI Mouse Phenotypes related to Acute Cervicitis:

46
# Description MGI Source Accession Score Top Affiliating Genes
1 hematopoietic system MP:0005397 9.56 CCL5 CD276 CD86 CSF2 CXCL10 SERPIND1
2 immune system MP:0005387 9.17 CCL5 CD276 CD86 CSF2 CXCL10 TLR2

Drugs & Therapeutics for Acute Cervicitis

Search Clinical Trials , NIH Clinical Center for Acute Cervicitis

Genetic Tests for Acute Cervicitis

Anatomical Context for Acute Cervicitis

MalaCards organs/tissues related to Acute Cervicitis:

41
Spinal Cord

Publications for Acute Cervicitis

Articles related to Acute Cervicitis:

(show all 49)
# Title Authors Year
1
New biomarkers of human papillomavirus infection in acute cervical intraepithelial neoplasia. ( 29966832 )
2018
2
Identifying acute cervicitis in an era of less-frequent routine gynecologic examinations. ( 29369931 )
2018
3
Impact of Admission Imaging Findings on Neurological Outcomes in Acute Cervical Traumatic Spinal Cord Injury. ( 29361876 )
2018
4
Systemic Hypothermia as Treatment for an Acute Cervical Spinal Cord Injury in a Professional Football Player: 9-Year Follow-Up. ( 28437499 )
2017
5
Acute Cervical Dystonia Induced by Clebopride. ( 29333306 )
2017
6
Acute cervical myelitis and microscopic polyangiitis. ( 27158038 )
2016
7
Relationship Between Depressive State and Treatment Characteristics of Acute Cervical Spinal Cord Injury in Japan. ( 26567604 )
2015
8
A rare complication of wasp sting: acute cervical dystonia. ( 26499128 )
2015
9
Acute cervical cord infarction in anterior spinal artery territory with acute swelling mimicking myelitis. ( 26492118 )
2015
10
Respiratory CO2 response in acute cervical spinal cord injury (CO2 response in spinal cord injury). ( 24100664 )
2014
11
Acute cervical segmental denervation in neuromyelitis optica spectrum disorder. ( 25415521 )
2014
12
Mortality and morbidity after high-dose methylprednisolone treatment in patients with acute cervical spinal cord injury: a propensity-matched analysis using a nationwide administrative database. ( 23449889 )
2014
13
Acute Cervical Myelopathy Due to Presumed Fibrocartilaginous Embolism: A Case Report and Systematic Review of the Literature. ( 24901879 )
2014
14
Laminoplasty versus conservative treatment for acute cervical spinal cordA injury caused by ossification of the posterior longitudinal ligament after minor trauma. ( 24200415 )
2014
15
Acute prevertebral calcific tendinitis: a source of non-surgical acute cervical pain. ( 23864065 )
2014
16
Acute cervical lymphadenitis and infections of the retropharyngeal and parapharyngeal spaces in children. ( 25206314 )
2014
17
Directional preference following epidural steroid injection in three patients with acute cervical radiculopathy. ( 23113937 )
2013
18
Acute cervical internal carotid artery occlusion stroke. ( 23753968 )
2013
19
Clinical Correlates of High Cervical Fractional Anisotropy in Acute Cervical Spinal Cord Injury. ( 24055569 )
2013
20
Endovascular intervention for acute cervical carotid artery occlusion. ( 23605254 )
2013
21
Acute cervicitis and vulvovaginitis may be associated with Cytomegalovirus. ( 23606387 )
2013
22
Acute cervical internal carotid artery occlusion stroke--reply. ( 23753969 )
2013
23
Treatment of acute cervical internal carotid artery dissection using the Solitaire FR revascularization device. ( 23299103 )
2013
24
Acute cervical dystonia after the first dose of butamirate citrate. ( 23283272 )
2013
25
Calcific retropharyngeal tendinitis of the longus colli muscle. Answer to the e-quid "Acute cervical pain and dysphagia in a 43A year-old man". ( 23357277 )
2013
26
Treatment of acute cervical internal carotid artery dissection using the Solitaire FR revascularization device. ( 23257942 )
2012
27
Pulmonary function and expiratory flow limitation in acute cervical spinal cord injury. ( 22543017 )
2012
28
High-dose ambroxol reduces pulmonary complications in patients with acute cervical spinal cord injury after surgery. ( 22006379 )
2012
29
Stroke From Acute Cervical Internal Carotid Artery Occlusion: Treatment Results and Predictors of Outcome. ( 23007611 )
2012
30
Neurosarcoidosis mimicking acute cervical disc prolapse. ( 21344970 )
2011
31
Acute cervical spinal subdural hematoma not related to head injury. ( 20617096 )
2010
32
Acute cervical lymphadenitis caused by Mycobacterium florentinum. ( 20735941 )
2010
33
Clinical outcomes using modest intravascular hypothermia after acute cervical spinal cord injury. ( 20190669 )
2010
34
Guillain-barrAc syndrome combined with acute cervical myelopathy. ( 21082065 )
2010
35
Management of acute cervical compression fractures in two patients with osteogenesis imperfecta. ( 20881659 )
2010
36
Acute cervical radiculopathies in spontaneous intracranial hypotension. ( 19277760 )
2009
37
The efficacy of topical thiocolchicoside (Muscoril) in the treatment of acute cervical myofascial pain syndrome: a single-blind, randomized, prospective, phase IV clinical study. ( 19780000 )
2009
38
Brain-derived neurotrophic factor gene transfer with adeno-associated viral and lentiviral vectors prevents rubrospinal neuronal atrophy and stimulates regeneration-associated gene expression after acute cervical spinal cord injury. ( 17495772 )
2007
39
Acute cervical motor radiculopathy induced by neck and limb immobilization in a patient with Parkinson disease. ( 16847370 )
2006
40
Sudden quadriplegia after acute cervical disc herniation. ( 16225180 )
2005
41
Management of acute cervical spinal cord injury. ( 12803670 )
2001
42
Vertebral artery occlusion after acute cervical spine trauma. ( 10788863 )
2000
43
MRI assessment of the pre-vertebral soft tissues in acute cervical spine trauma. ( 10624353 )
1999
44
Bilateral internuclear ophthalmoplegia due to acute cervical hyperextension without head trauma. ( 2526155 )
1989
45
Acute cervical myelopathy from hereditary multiple exostoses: case report. ( 2788828 )
1989
46
The aetiology of acute cervical adenitis in children: serological and bacteriological studies. ( 6987407 )
1980
47
The copper-7 device in chronic and IUD-induced acute cervicitis treated with oral estriol. ( 4614936 )
1974
48
Acute Cervical Hydrarthrosis. ( 19790510 )
1964
49
VERTEBRAL ARTERY INSUFFICIENCY IN ACUTE CERVICAL SPINE TRAUMA. ( 14159654 )
1964

Variations for Acute Cervicitis

Expression for Acute Cervicitis

Search GEO for disease gene expression data for Acute Cervicitis.

Pathways for Acute Cervicitis

Pathways related to Acute Cervicitis according to GeneCards Suite gene sharing:

(show all 25)
# Super pathways Score Top Affiliating Genes
1
Show member pathways
13.79 CCL4 CCL5 CD86 CSF2 CXCL1 CXCL10
2
Show member pathways
13.46 CCL4 CCL5 CSF2 CXCL1 CXCL10 CXCL5
3
Show member pathways
13.13 CCL4 CCL5 CD86 CSF2 CXCL1 CXCL10
4
Show member pathways
13.12 CCL4 CCL5 CSF2 CXCL1 CXCL10 CXCL5
5
Show member pathways
13.08 CCL4 CCL5 CSF2 CXCL1 CXCL10 CXCL5
6
Show member pathways
12.72 CCL4 CCL5 CD86 CXCL1 CXCL10 TLR2
7
Show member pathways
12.66 CCL4 CCL5 CXCL1 CXCL10 CXCL5
8
Show member pathways
12.59 CCL5 CXCL10 TLR2 TLR4
9
Show member pathways
12.56 CCL4 CCL5 CXCL10 TLR4
10
Show member pathways
12.39 CD86 CSF2 CXCL1 TLR2 TLR4
11 12.38 CCL5 CD276 CXCL10 TLR2
12
Show member pathways
12.13 CSF2 CXCL1 CXCL10 CXCL5 TLR2
13
Show member pathways
12.07 CD86 TLR2 TLR4
14
Show member pathways
12 CXCL10 TLR2 TLR4
15 11.84 CXCL1 CXCL10 TLR4
16 11.74 CSF2 CXCL1 TLR2 TLR4
17
Show member pathways
11.72 CCL4 CCL5 CXCL1 CXCL10 CXCL5
18
Show member pathways
11.7 CSF2 CXCL1 TLR4
19 11.67 CCL4 CSF2 CXCL1 TLR4
20 11.59 CCL5 CSF2 CXCL1 CXCL10 CXCL5
21 11.5 CCL4 CCL5 CSF2
22 11.41 CXCL1 TLR2 TLR4
23 11.12 CCL4 CCL5 CD86 CSF2 CXCL1 CXCL10
24 11.12 CCL5 CD86 CSF2 CXCL1 CXCL5 TLR2
25 11.1 CSF2 CXCL1

GO Terms for Acute Cervicitis

Cellular components related to Acute Cervicitis according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 extracellular region GO:0005576 9.7 CCL4 CCL5 CSF2 CXCL1 CXCL10 CXCL5
2 intrinsic component of plasma membrane GO:0031226 9.26 TLR2 TLR4
3 external side of plasma membrane GO:0009897 9.26 CD276 CD86 CXCL10 TLR4
4 extracellular space GO:0005615 9.17 CCL4 CCL5 CSF2 CXCL1 CXCL10 CXCL5

Biological processes related to Acute Cervicitis according to GeneCards Suite gene sharing:

(show all 43)
# Name GO ID Score Top Affiliating Genes
1 positive regulation of cell proliferation GO:0008284 9.97 CD86 CSF2 CXCL10 CXCL5
2 cell-cell signaling GO:0007267 9.88 CCL4 CCL5 CXCL10 CXCL5
3 regulation of signaling receptor activity GO:0010469 9.88 CCL4 CCL5 CSF2 CXCL1 CXCL10 CXCL5
4 positive regulation of ERK1 and ERK2 cascade GO:0070374 9.86 CCL4 CCL5 TLR4
5 regulation of cell proliferation GO:0042127 9.84 CSF2 CXCL1 CXCL10 CXCL5
6 defense response GO:0006952 9.81 CXCL1 CXCL10 CXCL5
7 cytokine-mediated signaling pathway GO:0019221 9.8 CCL4 CCL5 CD86 CSF2 CXCL1 CXCL10
8 response to virus GO:0009615 9.79 CCL4 CCL5 CXCL10
9 cellular response to lipopolysaccharide GO:0071222 9.78 CD86 CSF2 CXCL10 TLR4
10 response to toxic substance GO:0009636 9.77 CCL4 CCL5 TLR2
11 response to lipopolysaccharide GO:0032496 9.77 CXCL1 CXCL10 CXCL5 TLR2 TLR4
12 cell chemotaxis GO:0060326 9.73 CCL5 CXCL1 CXCL10 CXCL5
13 positive regulation of inflammatory response GO:0050729 9.72 CCL4 TLR2 TLR4
14 inflammatory response GO:0006954 9.7 CCL4 CCL5 CXCL1 CXCL10 CXCL5 TLR2
15 toll-like receptor signaling pathway GO:0002224 9.69 TLR2 TLR4
16 monocyte chemotaxis GO:0002548 9.69 CCL4 CCL5
17 positive regulation of T cell proliferation GO:0042102 9.69 CCL5 CD276 CD86
18 lymphocyte chemotaxis GO:0048247 9.68 CCL4 CCL5
19 MyD88-dependent toll-like receptor signaling pathway GO:0002755 9.68 TLR2 TLR4
20 positive regulation of neutrophil chemotaxis GO:0090023 9.67 CXCL1 CXCL5
21 positive regulation of interleukin-8 production GO:0032757 9.67 TLR2 TLR4
22 lipopolysaccharide-mediated signaling pathway GO:0031663 9.67 CCL5 TLR2 TLR4
23 positive regulation of interferon-beta production GO:0032728 9.66 TLR2 TLR4
24 positive regulation of interleukin-12 production GO:0032735 9.66 TLR2 TLR4
25 eosinophil chemotaxis GO:0048245 9.65 CCL4 CCL5
26 positive regulation of calcium ion transport GO:0051928 9.65 CCL4 CCL5
27 positive regulation of interleukin-10 production GO:0032733 9.65 TLR2 TLR4
28 chemokine-mediated signaling pathway GO:0070098 9.65 CCL4 CCL5 CXCL1 CXCL10 CXCL5
29 positive regulation of chemokine production GO:0032722 9.64 TLR2 TLR4
30 positive regulation of monocyte chemotaxis GO:0090026 9.63 CCL5 CXCL10
31 positive regulation of T cell migration GO:2000406 9.63 CCL5 CXCL10
32 positive regulation of leukocyte chemotaxis GO:0002690 9.63 CXCL1 CXCL10 CXCL5
33 positive regulation of nitric-oxide synthase biosynthetic process GO:0051770 9.62 TLR2 TLR4
34 negative regulation by host of viral transcription GO:0043922 9.61 CCL4 CCL5
35 I-kappaB phosphorylation GO:0007252 9.61 TLR2 TLR4
36 regulation of cytokine secretion GO:0050707 9.59 TLR2 TLR4
37 cellular response to lipoteichoic acid GO:0071223 9.58 TLR2 TLR4
38 macrophage activation GO:0042116 9.57 CSF2 TLR4
39 positive regulation of natural killer cell chemotaxis GO:2000503 9.52 CCL4 CCL5
40 chemotaxis GO:0006935 9.43 CCL4 CCL5 CXCL1 CXCL10 CXCL5 SERPIND1
41 immune response GO:0006955 9.32 CCL4 CCL5 CD276 CD86 CSF2 CXCL1
42 signal transduction GO:0007165 10.1 CCL4 CD86 CXCL1 CXCL10 CXCL5 TLR2
43 G-protein coupled receptor signaling pathway GO:0007186 10.07 CCL4 CCL5 CXCL1 CXCL10 CXCL5

Molecular functions related to Acute Cervicitis according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 signaling receptor binding GO:0005102 9.71 CD276 CXCL1 CXCL10 TLR4
2 signaling receptor activity GO:0038023 9.61 CD86 TLR2 TLR4
3 lipopolysaccharide binding GO:0001530 9.48 TLR2 TLR4
4 CCR chemokine receptor binding GO:0048020 9.46 CCL4 CCL5
5 cytokine activity GO:0005125 9.43 CCL4 CCL5 CSF2 CXCL1 CXCL10 CXCL5
6 CCR5 chemokine receptor binding GO:0031730 9.37 CCL4 CCL5
7 CXCR chemokine receptor binding GO:0045236 9.33 CXCL1 CXCL10 CXCL5
8 CCR1 chemokine receptor binding GO:0031726 9.32 CCL4 CCL5
9 lipopolysaccharide receptor activity GO:0001875 9.26 TLR2 TLR4
10 chemokine activity GO:0008009 9.02 CCL4 CCL5 CXCL1 CXCL10 CXCL5

Sources for Acute Cervicitis

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
17 ExPASy
19 FMA
28 GO
29 GTR
30 HGMD
31 HMDB
32 HPO
33 ICD10
34 ICD10 via Orphanet
35 ICD9CM
36 IUPHAR
37 KEGG
38 LifeMap
40 LOVD
42 MedGen
44 MeSH
45 MESH via Orphanet
46 MGI
49 NCI
50 NCIt
51 NDF-RT
54 NINDS
55 Novoseek
57 OMIM
58 OMIM via Orphanet
62 PubMed
64 QIAGEN
69 SNOMED-CT via HPO
70 SNOMED-CT via Orphanet
71 TGDB
72 Tocris
73 UMLS
74 UMLS via Orphanet
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