MCID: ACT066
MIFTS: 30

Acute Cervicitis

Categories: Reproductive diseases

Aliases & Classifications for Acute Cervicitis

MalaCards integrated aliases for Acute Cervicitis:

Name: Acute Cervicitis 12 15 74

Classifications:



External Ids:

Disease Ontology 12 DOID:10616
NCIt 51 C27056
SNOMED-CT 69 19272000
UMLS 74 C0269061

Summaries for Acute Cervicitis

Disease Ontology : 12 A cervicitis that is characterized by onset within the past 1 - 3 days.

MalaCards based summary : Acute Cervicitis is related to cervicitis and acute gonococcal cervicitis. An important gene associated with Acute Cervicitis is MT-TG (Mitochondrially Encoded TRNA-Gly (GGN)), and among its related pathways/superpathways are Innate Immune System and PEDF Induced Signaling. Affiliated tissues include lung, bone and spinal cord.

Related Diseases for Acute Cervicitis

Diseases in the Cervicitis family:

Acute Cervicitis Chronic Cervicitis

Diseases related to Acute Cervicitis via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50) (show all 103)
# Related Disease Score Top Affiliating Genes
1 cervicitis 30.3 MT-TG SERPIND1
2 acute gonococcal cervicitis 11.1
3 spinal cord injury 10.3
4 spotted fever 10.2 CCL5 CXCL10
5 endocervicitis 10.2 MT-TG TLR4
6 autoimmune peripheral neuropathy 10.2 CD86 CXCL10
7 neurosyphilis 10.2 CXCL10 TLR2
8 viral meningitis 10.2 CCL5 CXCL10
9 prosthetic joint infection 10.1 TLR2 TLR4
10 trench fever 10.1 TLR2 TLR4
11 japanese encephalitis 10.1 CCL5 CXCL10
12 genital herpes 10.1 CCL5 TLR2
13 fungal keratitis 10.1 TLR2 TLR4
14 suppurative otitis media 10.1 TLR2 TLR4
15 spondylarthropathy 10.1 TLR2 TLR4
16 neisseria meningitidis infection 10.1 TLR2 TLR4
17 alveolar echinococcosis 10.1 TLR2 TLR4
18 septic arthritis 10.1 TLR2 TLR4
19 scrub typhus 10.0 TLR2 TLR4
20 irak4 deficiency 10.0 TLR2 TLR4
21 viral encephalitis 10.0 CCL5 CXCL10
22 myd88 deficiency 10.0 TLR2 TLR4
23 middle ear disease 10.0 TLR2 TLR4
24 omsk hemorrhagic fever 10.0 CCL4 CCL5
25 japanese spotted fever 10.0 CCL4 CXCL10
26 radiculopathy 10.0
27 cervical adenitis 10.0
28 pelvic inflammatory disease 10.0 TLR2 TLR4
29 whiplash 10.0 CCL4 CCL5
30 pulmonary disease, chronic obstructive 10.0 CCL5 CXCL10 TLR2
31 invasive aspergillosis 9.9 CXCL10 TLR2 TLR4
32 lymphadenitis 9.9
33 chronic nk-cell lymphocytosis 9.9 CCL4 CCL5
34 stachybotrys chartarum 9.9 CCL4 CCL5
35 penicilliosis 9.9 CD86 TLR2 TLR4
36 myositis fibrosa 9.9 CD86 TLR2 TLR4
37 primary bacterial infectious disease 9.9 CXCL10 TLR2 TLR4
38 glaucomatocyclitic crisis 9.9 CCL4 CXCL10
39 q fever 9.9 TLR2 TLR4
40 eosinophilic pneumonia 9.9 CCL5 CSF2
41 mycobacterium tuberculosis 1 9.9 CXCL10 TLR2 TLR4
42 pulmonary sarcoidosis 9.9 CCL5 CSF2 CXCL5
43 filariasis 9.9 CCL5 TLR2 TLR4
44 idiopathic neutropenia 9.9 CCL5 TLR4
45 tendinitis 9.9
46 carotid artery occlusion 9.9
47 mastitis 9.8 CCL5 CSF2 TLR2
48 keratitis, hereditary 9.8 CXCL1 TLR2 TLR4
49 cervical dystonia 9.8
50 dystonia 9.8

Graphical network of the top 20 diseases related to Acute Cervicitis:



Diseases related to Acute Cervicitis

Symptoms & Phenotypes for Acute Cervicitis

Drugs & Therapeutics for Acute Cervicitis

Search Clinical Trials , NIH Clinical Center for Acute Cervicitis

Genetic Tests for Acute Cervicitis

Anatomical Context for Acute Cervicitis

MalaCards organs/tissues related to Acute Cervicitis:

42
Lung, Bone, Spinal Cord, Nk Cells

Publications for Acute Cervicitis

Articles related to Acute Cervicitis:

# Title Authors Year
1
Identifying acute cervicitis in an era of less-frequent routine gynecologic examinations. ( 29369931 )
2018
2
Acute cervicitis and vulvovaginitis may be associated with Cytomegalovirus. ( 23606387 )
2013
3
The copper-7 device in chronic and IUD-induced acute cervicitis treated with oral estriol. ( 4614936 )
1974

Variations for Acute Cervicitis

Expression for Acute Cervicitis

Search GEO for disease gene expression data for Acute Cervicitis.

Pathways for Acute Cervicitis

Pathways related to Acute Cervicitis according to GeneCards Suite gene sharing:

(show all 28)
# Super pathways Score Top Affiliating Genes
1
Show member pathways
13.83 CCL4 CCL5 CD86 CSF2 CXCL1 CXCL10
2
Show member pathways
13.48 CCL4 CCL5 CSF2 CXCL1 CXCL10 CXCL5
3
Show member pathways
13.24 CCL4 CCL5 CSF2 CXCL1 CXCL10 CXCL5
4
Show member pathways
13.18 CCL4 CCL5 CD86 CSF2 CXCL1 CXCL10
5
Show member pathways
13.12 CCL4 CCL5 CSF2 CXCL1 CXCL10 CXCL5
6
Show member pathways
12.91 CCL4 CCL5 CD86 CXCL1 CXCL10 TLR2
7
Show member pathways
12.8 CCL4 CCL5 CD86 CSF2 CXCL1 TLR2
8
Show member pathways
12.72 CCL4 CCL5 CXCL1 CXCL10 CXCL5
9
Show member pathways
12.59 CCL4 CCL5 CXCL10 TLR4
10
Show member pathways
12.21 CSF2 CXCL1 CXCL10 CXCL5 TLR2
11
Show member pathways
12.05 CCL4 CCL5 CXCL1 CXCL10 CXCL5 TLR2
12
Show member pathways
12.02 CXCL10 TLR2 TLR4
13
Show member pathways
11.91 CD86 TLR2 TLR4
14
Show member pathways
11.89 CSF2 TLR2 TLR4
15 11.86 CXCL1 CXCL10 TLR4
16
Show member pathways
11.83 CCL4 CCL5 CXCL1 CXCL10 CXCL5
17 11.82 CSF2 CXCL1 TLR2 TLR4
18 11.76 CCL5 CSF2 CXCL1 CXCL10 CXCL5
19 11.75 CCL4 CSF2 CXCL1 TLR4
20
Show member pathways
11.73 CSF2 CXCL1 TLR4
21 11.53 CCL4 CCL5 CSF2
22 11.48 CCL4 CCL5 CD86 CSF2 CXCL1 CXCL10
23 11.46 CXCL1 TLR2 TLR4
24 11.13 CCL5 CD86 CSF2 CXCL1 CXCL5 TLR2
25 11.12 CCL4 CCL5 CD86 CSF2 CXCL1 CXCL10
26 11.1 CSF2 CXCL1
27 10.96 CCL4 CCL5 CSF2 CXCL1 CXCL10 CXCL5
28 10.9 CCL4 CCL5 CSF2 CXCL1 CXCL10 CXCL5

GO Terms for Acute Cervicitis

Cellular components related to Acute Cervicitis according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 extracellular region GO:0005576 9.5 CCL4 CCL5 CSF2 CXCL1 CXCL10 CXCL5
2 extracellular space GO:0005615 9.17 CCL4 CCL5 CSF2 CXCL1 CXCL10 CXCL5
3 intrinsic component of plasma membrane GO:0031226 9.16 TLR2 TLR4

Biological processes related to Acute Cervicitis according to GeneCards Suite gene sharing:

(show all 41)
# Name GO ID Score Top Affiliating Genes
1 positive regulation of cell proliferation GO:0008284 9.97 CD86 CSF2 CXCL10 CXCL5
2 regulation of signaling receptor activity GO:0010469 9.91 CCL4 CCL5 CSF2 CXCL1 CXCL10 CXCL5
3 cytokine-mediated signaling pathway GO:0019221 9.88 CCL4 CCL5 CD86 CSF2 CXCL1 CXCL10
4 response to lipopolysaccharide GO:0032496 9.83 CXCL10 TLR2 TLR4
5 cell-cell signaling GO:0007267 9.83 CCL4 CCL5 CXCL10 CXCL5
6 defense response GO:0006952 9.81 CXCL1 CXCL10 CXCL5
7 inflammatory response GO:0006954 9.8 CCL4 CCL5 CXCL1 CXCL10 CXCL5 TLR2
8 response to virus GO:0009615 9.79 CCL4 CCL5 CXCL10
9 neutrophil chemotaxis GO:0030593 9.77 CCL4 CCL5 CXCL1 CXCL10 CXCL5
10 response to toxic substance GO:0009636 9.76 CCL4 CCL5 TLR2
11 cellular response to interferon-gamma GO:0071346 9.76 CCL4 CCL5 TLR2 TLR4
12 cell chemotaxis GO:0060326 9.74 CCL5 CXCL10 CXCL5
13 antimicrobial humoral immune response mediated by antimicrobial peptide GO:0061844 9.72 CXCL1 CXCL10 CXCL5
14 chemokine-mediated signaling pathway GO:0070098 9.72 CCL4 CCL5 CXCL1 CXCL10 CXCL5
15 lipopolysaccharide-mediated signaling pathway GO:0031663 9.69 CCL5 TLR2 TLR4
16 toll-like receptor signaling pathway GO:0002224 9.68 TLR2 TLR4
17 lymphocyte chemotaxis GO:0048247 9.68 CCL4 CCL5
18 MyD88-dependent toll-like receptor signaling pathway GO:0002755 9.68 TLR2 TLR4
19 positive regulation of interleukin-8 production GO:0032757 9.67 TLR2 TLR4
20 positive regulation of interferon-beta production GO:0032728 9.67 TLR2 TLR4
21 positive regulation of calcium ion transport GO:0051928 9.66 CCL4 CCL5
22 positive regulation of interleukin-12 production GO:0032735 9.66 TLR2 TLR4
23 positive regulation of interleukin-10 production GO:0032733 9.65 TLR2 TLR4
24 eosinophil chemotaxis GO:0048245 9.65 CCL4 CCL5
25 leukocyte chemotaxis GO:0030595 9.65 CXCL1 CXCL10 CXCL5
26 positive regulation of chemokine production GO:0032722 9.64 TLR2 TLR4
27 positive regulation of monocyte chemotaxis GO:0090026 9.63 CCL5 CXCL10
28 positive regulation of T cell migration GO:2000406 9.63 CCL5 CXCL10
29 cellular response to lipopolysaccharide GO:0071222 9.63 CD86 CSF2 CXCL1 CXCL10 CXCL5 TLR4
30 positive regulation of nitric-oxide synthase biosynthetic process GO:0051770 9.62 TLR2 TLR4
31 regulation of cytokine secretion GO:0050707 9.61 TLR2 TLR4
32 I-kappaB phosphorylation GO:0007252 9.61 TLR2 TLR4
33 negative regulation by host of viral transcription GO:0043922 9.6 CCL4 CCL5
34 macrophage activation GO:0042116 9.59 CSF2 TLR4
35 cellular response to lipoteichoic acid GO:0071223 9.58 TLR2 TLR4
36 positive regulation of natural killer cell chemotaxis GO:2000503 9.54 CCL4 CCL5
37 positive regulation of cellular response to macrophage colony-stimulating factor stimulus GO:1903974 9.49 TLR2 TLR4
38 chemotaxis GO:0006935 9.43 CCL4 CCL5 CXCL1 CXCL10 CXCL5 SERPIND1
39 immune response GO:0006955 9.28 CCL4 CCL5 CD86 CSF2 CXCL1 CXCL10
40 signal transduction GO:0007165 10.1 CCL4 CD86 CXCL1 CXCL10 CXCL5 TLR2
41 G protein-coupled receptor signaling pathway GO:0007186 10.08 CCL4 CCL5 CXCL1 CXCL10 CXCL5

Molecular functions related to Acute Cervicitis according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 identical protein binding GO:0042802 9.77 CCL4 CCL5 CXCL5 TLR2 TLR4
2 signaling receptor activity GO:0038023 9.63 CD86 TLR2 TLR4
3 lipopolysaccharide binding GO:0001530 9.43 TLR2 TLR4
4 CCR chemokine receptor binding GO:0048020 9.4 CCL4 CCL5
5 cytokine activity GO:0005125 9.35 CCL4 CCL5 CSF2 CXCL1 CXCL10
6 CCR5 chemokine receptor binding GO:0031730 9.32 CCL4 CCL5
7 CCR1 chemokine receptor binding GO:0031726 9.26 CCL4 CCL5
8 lipopolysaccharide receptor activity GO:0001875 9.16 TLR2 TLR4
9 chemokine activity GO:0008009 9.02 CCL4 CCL5 CXCL1 CXCL10 CXCL5

Sources for Acute Cervicitis

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
17 EFO
18 ExPASy
20 FMA
29 GO
30 GTR
31 HGMD
32 HMDB
33 HPO
34 ICD10
35 ICD10 via Orphanet
36 ICD9CM
37 IUPHAR
38 KEGG
39 LifeMap
41 LOVD
43 MedGen
45 MeSH
46 MESH via Orphanet
47 MGI
50 NCI
51 NCIt
52 NDF-RT
55 NINDS
56 Novoseek
58 OMIM
59 OMIM via Orphanet
63 PubMed
65 QIAGEN
70 SNOMED-CT via HPO
71 SNOMED-CT via Orphanet
72 TGDB
73 Tocris
74 UMLS
75 UMLS via Orphanet
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