MCID: ACT028
MIFTS: 28

Acute Closed-Angle Glaucoma

Categories: Eye diseases

Aliases & Classifications for Acute Closed-Angle Glaucoma

MalaCards integrated aliases for Acute Closed-Angle Glaucoma:

Name: Acute Closed-Angle Glaucoma 12 15
Acute Angle-Closure Glaucoma 12 71

Classifications:



External Ids:

Disease Ontology 12 DOID:13862
ICD9CM 34 365.22
SNOMED-CT 67 30041005
ICD10 32 H40.21
UMLS 71 C0154946

Summaries for Acute Closed-Angle Glaucoma

MalaCards based summary : Acute Closed-Angle Glaucoma, also known as acute angle-closure glaucoma, is related to corneal edema and chronic closed-angle glaucoma. An important gene associated with Acute Closed-Angle Glaucoma is MYOC (Myocilin). The drugs Topiramate and Anticonvulsants have been mentioned in the context of this disorder. Affiliated tissues include eye, endothelial and testes.

Related Diseases for Acute Closed-Angle Glaucoma

Diseases in the Acute Closed-Angle Glaucoma family:

Chronic Closed-Angle Glaucoma

Diseases related to Acute Closed-Angle Glaucoma via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50) (show all 133)
# Related Disease Score Top Affiliating Genes
1 corneal edema 31.0 MYOC LAMA3
2 chronic closed-angle glaucoma 30.7 MYOC LAMA3 CTSA
3 optic nerve disease 30.5 POU4F1 OPTN MYOC
4 intraocular pressure quantitative trait locus 30.3 POU4F1 PEX19 OPTN MYOC CTSA
5 ocular hypertension 30.2 POU4F1 OPTN MYOC
6 primary angle-closure glaucoma 29.9 OPTN MYOC CALCRL
7 cataract 10.6
8 yemenite deaf-blind hypopigmentation syndrome 10.6
9 retinal detachment 10.5
10 myopia 10.5
11 headache 10.5
12 migraine with or without aura 1 10.5
13 ptosis 10.5
14 uveitis 10.4
15 neuropathy 10.4
16 macular degeneration, age-related, 1 10.3
17 miller fisher syndrome 10.3
18 melanoma, uveal 10.3
19 nonarteritic anterior ischemic optic neuropathy 10.3
20 retinitis pigmentosa 10.3
21 ataxia and polyneuropathy, adult-onset 10.3
22 kearns-sayre syndrome 10.3
23 neuroretinitis 10.3
24 hypopyon 10.3
25 lens subluxation 10.3
26 vogt-koyanagi-harada disease 10.3
27 retinitis 10.3
28 exophthalmos 10.3
29 autonomic dysfunction 10.3
30 macular dystrophy, dominant cystoid 10.2 PEX19 BEST1
31 iris disease 10.2 PEX19 MYOC
32 alcohol dependence 10.1
33 major affective disorder 1 10.1
34 exudative vitreoretinopathy 1 10.1
35 sturge-weber syndrome 10.1
36 von hippel-lindau syndrome 10.1
37 moyamoya disease 1 10.1
38 pseudoxanthoma elasticum 10.1
39 coats disease 10.1
40 choroideremia 10.1
41 astigmatism 10.1
42 pars planitis 10.1
43 pulmonary disease, chronic obstructive 10.1
44 granulomatosis with polyangiitis 10.1
45 human immunodeficiency virus type 1 10.1
46 microvascular complications of diabetes 5 10.1
47 aspergillosis 10.1
48 hydrops, lactic acidosis, and sideroblastic anemia 10.1
49 mucopolysaccharidosis-plus syndrome 10.1
50 invasive aspergillosis 10.1

Comorbidity relations with Acute Closed-Angle Glaucoma via Phenotypic Disease Network (PDN):


Hypertension, Essential

Graphical network of the top 20 diseases related to Acute Closed-Angle Glaucoma:



Diseases related to Acute Closed-Angle Glaucoma

Symptoms & Phenotypes for Acute Closed-Angle Glaucoma

Drugs & Therapeutics for Acute Closed-Angle Glaucoma

Drugs for Acute Closed-Angle Glaucoma (from DrugBank, HMDB, Dgidb, PharmGKB, IUPHAR, NovoSeek, BitterDB):

(show all 8)
# Name Status Phase Clinical Trials Cas Number PubChem Id
1
Topiramate Approved Phase 4 97240-79-4 5284627
2 Anticonvulsants Phase 4
3 Hypoglycemic Agents Phase 4
4
Mannitol Approved, Investigational 69-65-8 453 6251
5
Lutein Approved, Investigational, Nutraceutical 127-40-2 6433159
6 Natriuretic Agents
7 diuretics
8 Anesthetics

Interventional clinical trials:


# Name Status NCT ID Phase Drugs
1 Relationship Between Topiramate Use and Ocular Angle Status: A Prospective Pilot Study Unknown status NCT00153699 Phase 4 Topiramate
2 Phase IIA Double-Masked Randomized Sham-Controlled Trial of QPI-1007 Delivered by a Single Intravitreal Injection to Subjects With Acute Primary Angle-Closure Glaucoma (APACG) Completed NCT01965106 Phase 2 QPI-1007 Injection;(including placebo)
3 Structural and Functional Parameters in Caucasian Patients With Angle Closure on SS-OCT Unknown status NCT02054403
4 Comparison of Anterior Chamber Paracentesis and Conventional Mannitol Infusion in Patients With Primary Acute Angle-closure Glaucoma Completed NCT01266343
5 Incidence of Visual Symptom Following Laser (Nd:YAG ) Peripheral Iridotomy (LPI) in Relation to Position of LPI Completed NCT01758237
6 The Effect of Lutein-enriched-egg Beverage on Progression of Age-related Macular Degeneration, a Randomized Trial Completed NCT00902408
7 Short-term Outcomes of Iridoplasty for Persistent Angle Closure Despite Patent Iridotomies An Anterior Segment Optical Coherence Tomography Study Completed NCT02199158
8 Optic Nerve Compliance Study Completed NCT00328835
9 Angle Closure: Laser Iridotomy Versus Phacoemulsification Study (ACLIPS)- A Study of Acute Primary Angle Closure Glaucoma Comparing Two Treatment Modalities: Laser Peripheral vs Phacoemulsification With Posterior Intraocular Lens Implant Completed NCT00350428

Search NIH Clinical Center for Acute Closed-Angle Glaucoma

Genetic Tests for Acute Closed-Angle Glaucoma

Anatomical Context for Acute Closed-Angle Glaucoma

MalaCards organs/tissues related to Acute Closed-Angle Glaucoma:

40
Eye, Endothelial, Testes, Bone, Kidney, Skin

Publications for Acute Closed-Angle Glaucoma

Articles related to Acute Closed-Angle Glaucoma:

(show top 50) (show all 612)
# Title Authors PMID Year
1
Benzodiazepine Use and Risk of Acute Angle-Closure Glaucoma: A Population-Based Case-Crossover Study. 61
32034700 2020
2
Systemic Administration of an Apelin Receptor Agonist Prevents NMDA-Induced Loss of Retinal Neuronal Cells in Mice. 61
31894462 2020
3
Symptomatic bradycardia associated with acute angle closure glaucoma. 61
31975522 2020
4
Topiramate-Associated Acute Angle Closure Glaucoma With Myopic Shift. 61
32039989 2020
5
Acute angle closure glaucoma. 61
31822188 2019
6
Nationwide Incidence of Acute Angle Closure Glaucoma in Korea from 2011 to 2015. 61
31833263 2019
7
Infectious keratitis secondary to canaliculitis with concretions: A case report. 61
31577768 2019
8
Ciliochoroidal effusion in topiramate-induced bilateral acute angle closure glaucoma. 61
31436195 2019
9
A Convergence of Ophthalmic and Life-threatening Emergencies: Acute Angle Closure Glaucoma and Subarachnoid Hemorrhage. 61
31233457 2019
10
Association of Gabapentin or Pregabalin Use and Incidence of Acute Angle-closure Glaucoma. 61
31335554 2019
11
Aqueous humor levels of TGFβ2 and SFRP1 in different types of glaucoma. 61
31382918 2019
12
A new rhodopsin R135W mutation induces endoplasmic reticulum stress and apoptosis in retinal pigment epithelial cells. 61
30635925 2019
13
Rare cause of acute angle-closure glaucoma in an elderly man. 61
31326909 2019
14
Association between use of benzodiazepines and occurrence of acute angle-closure glaucoma in the elderly: A population-based study. 61
31126405 2019
15
Acute angle-closure glaucoma with choroidal effusion revealing a hantavirus infection: Description of ultrasound biomicroscopy imagery and optical coherence tomography Visante. 61
31256684 2019
16
Non-prescription cold and flu medication-induced transient myopia with uveal effusion: case report. 61
31242876 2019
17
Postoperative Acute Angle-Closure Glaucoma: A Rare but Serious Complication: A Case Report. 61
31162162 2019
18
Impact of acute intraocular pressure elevation on the visual acuity of non-human primates. 61
31178426 2019
19
AUTOSOMAL DOMINANT VITREORETINOCHOROIDOPATHY: When Molecular Genetic Testing Helps Clinical Diagnosis. 61
29370033 2019
20
Acute Angle Closure Glaucoma in Von Hippel-Lindau Syndrome. 61
31005188 2019
21
Complete Anterior Capsule Phimosis following Cataract Surgery in a Patient with a History of Retinopathy of Prematurity, Nystagmus, and a Narrow Angle. 61
31692622 2019
22
Acute Angle-Closure Glaucoma Secondary to a Phakic Intraocular Lens, an Ophthalmic Emergency. 61
31061970 2019
23
Primary Acute Angle-Closure Glaucoma: Three-Dimensional Reconstruction Imaging of Optic Nerve Heard Structure in Based on Optical Coherence Tomography (OCT). 61
31096262 2019
24
Acute narrow-angle glaucoma induced by topiramate with acute myopia and macular striae: A case report. 61
30591244 2019
25
Evaluation and Management of the Emergency Department Headache. 61
30743289 2019
26
Bilateral Acute Angle-Closure Glaucoma after Macular Hole Surgery. 61
30746920 2019
27
Large choroidal melanoma presenting as neovascular glaucoma. 61
31293875 2019
28
Acute angle closure glaucoma from spontaneous massive subretinal hemorrhage. 61
31157157 2019
29
[Effectiveness of the system for predicting the risk of developing an acute angle closure glaucoma attack]. 61
30830074 2019
30
Panscleritis masquerading as an attack of primary acute angle closure glaucoma. 61
31531277 2019
31
Postoperative Acute Angle-Closure Glaucoma: A Rare but Serious Complication: A Case Report. 61
30633003 2019
32
Measurement of Retinal Changes in Primary Acute Angle Closure Glaucoma under Different Durations of Symptoms. 61
31885888 2019
33
Combined treatment of phacoemulsification and single-port limited pars plana vitrectomy in acute angle-closure glaucoma. 61
31236355 2019
34
Bilateral acute angle closure glaucoma and myopic shift by topiramate-induced ciliochoroidal effusion: case report and literature review. 61
29063980 2018
35
Primary acute angle-closure glaucoma complicating ciliochoroidal detachment: report of four cases and review of the literature. 61
29170973 2018
36
Uveitis and acute glaucoma as first presenting symptoms of sarcoidosis in a healthy male. 61
30194022 2018
37
An uncommon case of intermittent Pourfour du Petit Syndrome associated with acute angle-closure glaucoma successfully treated by laser iridotomy. 61
28674857 2018
38
Early Phacoemulsification After Acute Angle Closure in Patients With Coexisting Cataract. 61
30005031 2018
39
A Novel Association between Oxybutynin Use and Bilateral Acute Angle Closure Glaucoma: A Case Report and Literature Review. 61
30087808 2018
40
Acute Glaucoma Attack Following Microvascular Decompression Surgery for Trigeminal Neuralgia. 61
29769452 2018
41
A frameshift mutation in the CHM gene causes choroideremia with acute angle‑closure glaucoma. 61
29620233 2018
42
[Blinding spontaneous suprachoroidal haemorrhage in anticoagulant taking wet-AMD patients]. 61
29888658 2018
43
Phacomorphic Angle-closure Following Silicone Oil Tamponade in a Pediatric Patient. 61
29613981 2018
44
Acute Angle-Closure Glaucoma Caused by Venlafaxine. 61
29893371 2018
45
Endoscopic Goniosynechialysis for Acute Angle Closure Glaucoma Following Descemet's Stripping Automated Endothelial Keratoplasty. 61
30473604 2018
46
Acute angle closure glaucoma? 61
29665201 2018
47
Acute Angle-Closure Glaucoma. 61
29514027 2018
48
Acute Angle-closure Glaucoma as a First Presentation of Coats' Disease: A Case Report. 61
29176335 2018
49
Bilateral acute angle-closure glaucoma following tramadol subcutaneous administration. 61
29454329 2018
50
Acute Angle-closure Glaucoma Associated With Aripiprazole in the Setting of Plateau Iris Configuration. 61
29189543 2018

Variations for Acute Closed-Angle Glaucoma

Expression for Acute Closed-Angle Glaucoma

Search GEO for disease gene expression data for Acute Closed-Angle Glaucoma.

Pathways for Acute Closed-Angle Glaucoma

GO Terms for Acute Closed-Angle Glaucoma

Sources for Acute Closed-Angle Glaucoma

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
17 EFO
18 ExPASy
19 FMA
28 GO
29 GTR
30 HMDB
31 HPO
32 ICD10
33 ICD10 via Orphanet
34 ICD9CM
35 IUPHAR
36 KEGG
37 LifeMap
39 LOVD
41 MedGen
43 MeSH
44 MESH via Orphanet
45 MGI
48 NCI
49 NCIt
50 NDF-RT
53 NINDS
54 Novoseek
56 OMIM
57 OMIM via Orphanet
61 PubMed
63 QIAGEN
68 SNOMED-CT via HPO
69 TGDB
70 Tocris
71 UMLS
72 UMLS via Orphanet
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