Aliases & Classifications for Acute Cystitis

MalaCards integrated aliases for Acute Cystitis:

Name: Acute Cystitis 12 15 71 32
Urinary Tract Infection 12 17 71
Urinary Tract Infections 42 15
Recurrent Urinary Tract Infection 71

Classifications:



External Ids:

Disease Ontology 12 DOID:13148
ICD9CM 34 595.0
NCIt 49 C26934
SNOMED-CT 67 68226007
ICD10 32 N30.0 N39.0
UMLS 71 C0042029 C0149523 C0262655

Summaries for Acute Cystitis

MedlinePlus : 42 The urinary system is the body's drainage system for removing wastes and extra water. It includes two kidneys, two ureters, a bladder, and a urethra. Urinary tract infections (UTIs) are the second most common type of infection in the body. You may have a UTI if you notice Pain or burning when you urinate Fever, tiredness, or shakiness An urge to urinate often Pressure in your lower belly Urine that smells bad or looks cloudy or reddish Pain in your back or side below the ribs People of any age or sex can get UTIs. But about four times as many women get UTIs as men. You're also at higher risk if you have diabetes, need a tube to drain your bladder, or have a spinal cord injury. If you think you have a UTI it is important to see your doctor. Your doctor can tell if you have a UTI with a urine test. Treatment is with antibiotics. NIH: National Institute of Diabetes and Digestive and Kidney Diseases

MalaCards based summary : Acute Cystitis, also known as urinary tract infection, is related to autosomal dominant polycystic kidney disease and nephrolithiasis, calcium oxalate, and has symptoms including fever, pruritus and uti symptoms. An important gene associated with Acute Cystitis is IL6 (Interleukin 6), and among its related pathways/superpathways are Innate Immune System and Measles. The drugs acetic acid and Apricot have been mentioned in the context of this disorder. Affiliated tissues include kidney, prostate and spinal cord, and related phenotypes are Decreased viability in esophageal squamous lineage and adipose tissue

Disease Ontology : 12 A cystitis characterized by a sudden onset or severe symptoms.

Wikipedia : 74 A urinary tract infection (UTI) is an infection that affects part of the urinary tract. When it affects... more...

Related Diseases for Acute Cystitis

Diseases in the Cystitis family:

Acute Cystitis Chronic Cystitis

Diseases related to Acute Cystitis via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50) (show all 915)
# Related Disease Score Top Affiliating Genes
1 autosomal dominant polycystic kidney disease 33.1 LCN2 INS CCL2 ALB
2 nephrolithiasis, calcium oxalate 33.0 UMOD LCN2 INS CRP CCL2 ALB
3 cystitis 33.0 VIM UPK1A UMOD TLR4 IL6 IL18
4 ureteral disease 32.5 LCN2 IL6 CRP CCR6 CCL2 ALB
5 hydronephrosis 32.2 IL6 CRP CCL2 ALB
6 chronic pyelonephritis 32.0 UMOD TLR4 ALB
7 klebsiella pneumonia 31.8 CRP CCR6 ALB
8 end stage renal failure 31.8 UMOD IL6 CRP ALB
9 urinary tract obstruction 31.7 UMOD LCN2 KLK3 CRP CCR6 CCL2
10 urethritis 31.7 TLR4 KLK3 IL6 GPR182 CRP
11 interstitial cystitis 31.6 UPK1A UMOD IL6
12 chlamydia 31.6 TLR4 IL6 IL18 CRP CCL2
13 bronchitis 31.5 TLR4 IL6 CRP ALB
14 endocarditis 31.4 IL6 CRP ALB
15 chronic kidney disease 31.4 UMOD LCN2 INS IL6 CRP CCL2
16 osteomyelitis 31.3 TLR4 IL6 CCL2
17 kidney disease 31.3 UMOD LCN2 INS IL6 IL18 CRP
18 interstitial nephritis 31.3 UMOD CRP ALB
19 pre-eclampsia 31.3 TLR4 INS IL6 IL18 CRP ALB
20 acute kidney failure 31.3 UMOD LCN2 IL18 ALB
21 peritonitis 31.3 TLR4 IL6 IL18 CRP CCL2 ALB
22 otitis media 31.3 TLR4 IL6 CRP ALB
23 endophthalmitis 31.2 IL6 CRP ALB
24 acute pyelonephritis 31.2 LCN2 IL6 CRP ALB
25 bronchiolitis 31.2 TLR4 IL6 CRP CCL2
26 bacteriuria 31.2 UMOD TLR4 PAPOLG IL6 IL18 CXCL1
27 kawasaki disease 31.2 IL6 CRP CCL2 ALB
28 autoimmune disease 31.2 INS IL6 IL18 CRP CCR6 CCL2
29 decubitus ulcer 31.2 INS IL6 CRP ALB
30 clostridium difficile colitis 31.1 CRP CCR6 ALB
31 cerebrovascular disease 31.1 TLR4 INS IL6 CRP
32 toxic shock syndrome 31.1 TLR4 IL6 CRP
33 drug allergy 31.1 INS CRP ALB
34 anuria 31.1 LCN2 CRP ALB
35 uremia 31.1 INS IL6 CRP ALB
36 pyelonephritis 31.1 UMOD TLR4 LCN2 IL6 CRP CCL2
37 pyuria 31.1 LCN2 KLK3 IL6 CRP ALB
38 dermatitis 31.1 TLR4 IL6 IL18 CCR6
39 pneumonia 31.1 TLR4 IL6 IL18 CXCL1 CRP CCL2
40 vulvovaginitis 31.1 SLC5A4 SLC5A2 CCR6
41 sexual disorder 31.1 KLK3 INS ALB
42 acute kidney tubular necrosis 31.0 UMOD LCN2 IL6 IL18 ALB
43 placenta disease 31.0 INS IL6 CRP
44 reactive arthritis 31.0 TLR4 IL6 CRP CCR6
45 salmonellosis 31.0 TLR4 IL6 IL18 GPR182 CCR6 ALB
46 multiple sclerosis 31.0 TLR4 IL6 IL18 CXCL1 CCR6 CCL2
47 endometritis 31.0 TLR4 IL6 CXCL1
48 diabetes mellitus 31.0 UMOD TLR4 SLC5A2 LCN2 INS IL6
49 diverticulitis 31.0 IL6 CRP CCR6 ALB
50 congestive heart failure 31.0 INS IL6 CRP ALB

Comorbidity relations with Acute Cystitis via Phenotypic Disease Network (PDN): (show top 50) (show all 422)


3-Hydroxyacyl-Coa Dehydrogenase Deficiency Acquired Thrombocytopenia
Active Peptic Ulcer Disease Acute Anterolateral Myocardial Infarction
Acute Conjunctivitis Acute Cor Pulmonale
Acute Kidney Failure Acute Maxillary Sinusitis
Acute Myocardial Infarction Acute Pancreatitis
Acute Sphenoidal Sinusitis Acute Vascular Insufficiency of Intestine
Adjustment Disorder Adrenal Gland Disease
Agammaglobulinemia, X-Linked Age-Related Hearing Loss
Alcoholic Hepatitis Alcoholic Liver Cirrhosis
Alcoholic Neuropathy Algoneurodystrophy
Allergic Urticaria Alopecia, Neurologic Defects, and Endocrinopathy Syndrome
Alzheimer Disease Amnestic Disorder
Amyloidosis Anemia, Autoimmune Hemolytic
Anorexia Nervosa Anus Cancer
Anxiety Aortic Aneurysm
Aortic Atherosclerosis Aortic Valve Disease 1
Asthma Atrioventricular Block
Atrophic Gastritis Atypical Depressive Disorder
Autonomic Nervous System Disease Bacteremia 2
Bacterial Meningitis Balanoposthitis
Basilar Artery Insufficiency Benign Essential Hypertension
Benign Hypertensive Renal Disease Biliary Tract Disease
Bipolar Disorder Bladder Cancer
Bladder Disease Bladder Neck Obstruction
Bleeding Disorder, Platelet-Type, 11 Blepharitis

Graphical network of the top 20 diseases related to Acute Cystitis:



Diseases related to Acute Cystitis

Symptoms & Phenotypes for Acute Cystitis

UMLS symptoms related to Acute Cystitis:


fever, pruritus, uti symptoms

GenomeRNAi Phenotypes related to Acute Cystitis according to GeneCards Suite gene sharing:

26
# Description GenomeRNAi Source Accession Score Top Affiliating Genes
1 Decreased viability in esophageal squamous lineage GR00235-A 9.32 CD248 CXCL1 GPR182 IL18 IL6 KLK3

MGI Mouse Phenotypes related to Acute Cystitis:

45
# Description MGI Source Accession Score Top Affiliating Genes
1 adipose tissue MP:0005375 9.7 IL18 IL6 INS LCN2 SLC5A2 TLR4
2 cardiovascular system MP:0005385 9.65 ALB CCR6 CRP IL18 IL6 INS
3 immune system MP:0005387 9.44 ALB CCL2 CCR6 CD248 CRP IL18

Drugs & Therapeutics for Acute Cystitis

Drugs for Acute Cystitis (from DrugBank, HMDB, Dgidb, PharmGKB, IUPHAR, NovoSeek, BitterDB):

(show top 50) (show all 530)
# Name Status Phase Clinical Trials Cas Number PubChem Id
1
acetic acid Approved Phase 4 64-19-7 176
2 Apricot Approved Phase 4
3
Bethanechol Approved Phase 4 674-38-4 2370
4
Clarithromycin Approved Phase 4 81103-11-9 84029
5
Sargramostim Approved, Investigational Phase 4 123774-72-1, 83869-56-1
6
Acetylcysteine Approved, Investigational Phase 4 616-91-1 12035
7
Pentoxifylline Approved, Investigational Phase 4 6493-05-6 4740
8
Lansoprazole Approved, Investigational Phase 4 103577-45-3 3883
9
Dexlansoprazole Approved, Investigational Phase 4 138530-94-6, 103577-45-3 9578005
10
Sulfamethoxazole Approved Phase 4 723-46-6 5329
11
Celecoxib Approved, Investigational Phase 4 169590-42-5 2662
12
Ceftriaxone Approved Phase 4 73384-59-5 5479530 5361919
13
Doripenem Approved, Investigational Phase 4 148016-81-3 73303
14
Ibuprofen Approved Phase 4 15687-27-1 3672
15
Sulbactam Approved Phase 4 68373-14-8
16
Norfloxacin Approved Phase 4 70458-96-7 4539
17
Metronidazole Approved Phase 4 443-48-1 4173
18
Cefazolin Approved Phase 4 25953-19-9 656510 33255
19
Vancomycin Approved Phase 4 1404-90-6 441141 14969
20
Doxycycline Approved, Investigational, Vet_approved Phase 4 564-25-0 54671203
21
Doxazosin Approved Phase 4 74191-85-8 3157
22
Etanercept Approved, Investigational Phase 4 185243-69-0
23
Moxifloxacin Approved, Investigational Phase 4 151096-09-2, 354812-41-2 152946
24
Halofantrine Approved Phase 4 69756-53-2 37393
25
Metformin Approved Phase 4 657-24-9 14219 4091
26
Oxybutynin Approved, Investigational Phase 4 5633-20-5 4634
27
Tinidazole Approved, Investigational Phase 4 19387-91-8 5479
28
Silodosin Approved Phase 4 160970-54-7
29
Sultamicillin Approved, Investigational Phase 4 76497-13-7
30
Aztreonam Approved Phase 4 78110-38-0 5362041 5742832
31
Midazolam Approved, Illicit Phase 4 59467-70-8 4192
32
Acetaminophen Approved Phase 4 103-90-2 1983
33
Norgestimate Approved, Investigational Phase 4 35189-28-7 6540478
34
Ethinyl Estradiol Approved Phase 4 57-63-6 5991
35
Naproxen Approved, Vet_approved Phase 4 22204-53-1 1302 156391
36
Gliclazide Approved Phase 4 21187-98-4 3475
37
4-Aminopyridine Approved Phase 4 504-24-5 1727
38
leucovorin Approved Phase 4 58-05-9 6006 143
39
Trimethoprim Approved, Vet_approved Phase 4 738-70-5 5578
40
Piperacillin Approved Phase 4 66258-76-2 43672
41
Methylene blue Approved, Investigational Phase 4 61-73-4
42
Belladonna Approved, Experimental Phase 4
43
Tranexamic Acid Approved Phase 4 1197-18-8 5526
44
Bacitracin Approved, Vet_approved Phase 4 1405-87-4 439542 10909430
45
Neomycin Approved, Vet_approved Phase 4 1404-04-2 8378
46
Histamine Approved, Investigational Phase 4 51-45-6 774
47
Acarbose Approved, Investigational Phase 4 56180-94-0 441184
48
Mannitol Approved, Investigational Phase 4 69-65-8 453 6251
49
Ertapenem Approved, Investigational Phase 4 153832-46-3 150610
50
Tamsulosin Approved, Investigational Phase 4 106133-20-4 129211

Interventional clinical trials:

(show top 50) (show all 1012)
# Name Status NCT ID Phase Drugs
1 Low Dose Estriol With Lactobacilli (Gynoflor) Treatment for Preventing Recurrent Urinary Tract Infection in Postmenopausal Women: A Randomized, Open, Parallel-Group Study Unknown status NCT00900653 Phase 4 Gynoflor E (low dose estriol with lactobacillus)
2 The Efficacy of Solifenacin Succinate as Adjuvant Therapy for Symptomatic Non-complicated Urinary Tract Infection in Females Unknown status NCT02094703 Phase 4 Levofloxacin;Solifenacin succinate;Placebo (for Solifenacin succinate)
3 The Impact of Antimicrobial Treatment for Asymptomatic Bacteriuria in Renal Transplant Patients Unknown status NCT02113774 Phase 4
4 An Open Label Non Placebo Study to Evaluate Efficacy and Safety of Levofloxacin as an Empirical Therapy in Patients With Complicated Urinary Tract Infections Unknown status NCT03160807 Phase 4 Levofloxacin;Levofloxacin
5 Randomized Placebo-Controlled Trial of Gentamicin Bladder Instillation for the Prevention of Urinary Tract Infection in Adults at High Risk for Cystitis Due to Intermittent Catheterization Unknown status NCT01884467 Phase 4 Gentamicin;Placebo
6 Randomised Clinical Trial Comparing Fosfomycin vs. Nitrofurantoin for Treatment of Uncomplicated Lower Urinary Tract Infection in Female Adults at Increased Risk of Antibiotic-resistant Bacterial Infection Unknown status NCT01966653 Phase 4 nitrofurantoin;fosfomycin
7 A Open Multi-center Clinical Study on Piperacillin Sodium and Sulbactam Sodium for Injection (2:1) for Treatment of Respiratory and Urinary Tract Infection Unknown status NCT01897831 Phase 4 xin te mie
8 Evaluation of Suprapubic Noble Metal Alloy BIP Foley Catheter in the Prevention of Catheter-associated Urinary Tract Infections in Spinal Cord Injured Patients Unknown status NCT02808000 Phase 4
9 A Randomised, Double-blind, Placebo Controlled Trial Evaluating the Effectiveness of a Cranberry Concentrate (CranrichTM) in Preventing Recurrent Urinary Tract Infections in Adult Women Unknown status NCT02454309 Phase 4
10 Pilot Study to Evaluate the Efficacy of Antiseptic Bladder Lavage Versus Pulsatile Lavage With Physiologic Serum in Catheterized Patients With Asymptomatic Bacteriuria With Uropathogens. Unknown status NCT01772875 Phase 4
11 Comparison of the Effect of Applying Povidone-iodine and Chlorhexidine Solutions for Perinea Washing on Bacteriuria Rate and Type in Patients With Urinary Catheter in Intensive Care Unit Unknown status NCT02032394 Phase 4 Povidone-iodine;Chlorhexidine;Normal saline
12 Evaluation of the Effectiveness of Antibiotic Prophylaxis in Children With a History of Upper Urinary Tract Infections:a Multicentre Randomised Study Unknown status NCT00156546 Phase 4 antibiotic to reduce the recurrence of infection
13 The Effects of Vaginal Estrogen and a Nonhormonal Alternative on the Vaginal and Urinary Microbiome in Women With Genitourinary Syndrome of Menopause: A Randomized Controlled Trial Unknown status NCT02869165 Phase 4 Premarin vaginal cream;Apricot kernel oil
14 The Use of Toxin Botulinum A Toxin in Patients With Parkinson's Disease and Multiple System Disease, Affected by Refractory Detrusor Overactivity. Unknown status NCT00822913 Phase 4 Intravesical injection of Botulinum A toxin
15 Effectiveness of Bethanechol Chloride and Early Bladder Training for Prevention of Bladder Dysfunction After Radical Hysterectomy in Cervical Cancer Stage IB - IIA Unknown status NCT02910596 Phase 4 bethanechol chloride
16 Clinical Impact of Bacteriuria on Chronic Inflammation in Asymptomatic Hemodialysis Patients Unknown status NCT01570556 Phase 4
17 Functional Electrical Stimulation-Assisted Walking: Reduction of Secondary Complications Due to Spinal Cord Injury Unknown status NCT00201968 Phase 4
18 A Prospective Study Comparing the Success Rate of Injection of Dextranomer /Hyaluronic Acid (DefluxR) Versus Polyacrylate Polyalcohol (VantrisR) for Treatment of Bilateral Similar Grade Vesicoureteral Reflux in Children Unknown status NCT02271035 Phase 4 Deflux;Vantris
19 Effect of Vaginal Estrogen on Asymptomatic Microhematuria (AMH): A Randomized Controlled Trial [EVER Study] Unknown status NCT02213757 Phase 4 Premarin vaginal estrogen cream;Placebo vaginal cream
20 Granulocyte Colony Stimulating Factor Plus N-Acetyl Cysteine In Severe Alcoholic Hepatitis Unknown status NCT02971306 Phase 4 standard medical therapy;G-CSF;n-Acetylcysteine
21 Comparison of the Efficacy of Triple Therapy With or Without Acetylcysteine in the First Line of Helicobacter Pylori Infection- A Multicenter Randomized Comparative Trial Unknown status NCT02249546 Phase 4 N-acetylcysteine + PPI-amoxicillin-clarithromycin;PPI-amoxicillin-clarithromycin
22 Effect of Anti-diabetic Drugs on Glycemic Variability. A Comparison Between Gliclazide MR (Modified Release) and Dapagliflozin on Glycemic Variability Measured by Continuous Glucose Monitoring (CGM) in Patients With Uncontrolled Type 2 Diabetes Unknown status NCT02925559 Phase 4 Dapagliflozin;Gliclazide MR
23 Vaginal Estrogen for the Prevention of Recurrent Urinary Tract Infection in Postmenopausal Women Completed NCT01958073 Phase 4 Conjugated Estrogen Vaginal Cream;Estradiol Ring;Placebo
24 Use of Standardized Delegation Form in Diagnosing and Treating Acute Cystitis in Primary Care Facilities. Completed NCT01132131 Phase 4
25 Clinical and Microbiologic Efficacy of Ciprofloxacin for the Treatment of Uncomplicated Urinary Tract Infection in Adult Women. Completed NCT03366207 Phase 4 Ciprofloxacin
26 Prospective, Open Label Non-comparative, Multi-center Trial to Evaluate the Efficacy and Safety of Cipro® XR 500 mg Once Daily for 3 Days in Treating Female Patients With Acute, Uncomplicated, Symptomatic Lower Urinary Tract Infections Completed NCT00669994 Phase 4 Ciprofloxacin
27 Open Label Study on the Bacteriological and Clinical Efficacy and Safety of a Nitrofurantoin Formulation Given Twice Daily (Bid) for Seven Days in Uncomplicated Urinary Tract Infection in Adults Completed NCT01092351 Phase 4 Nitrofurantoin
28 Cipro® XR Excellence in Therapeutic Response and Activity (eXtRa) - Assessing Symptom Relief in Urinary Tract Infections Completed NCT00676533 Phase 4 Cipro XR (Ciprofloxacin, BAYQ3939)
29 Pharmacokinetics of Ciprofloxacin in Pediatric Patients With Emphasis on Renal Excretion Completed NCT02598362 Phase 4 ciprofloxacin
30 Use of Antibiotic Prophylaxis on Urethral Catheter Withdrawal: A Randomized Double-Blind Placebo-Controlled Trial Completed NCT00126698 Phase 4 trimethoprim-sulfamethoxazole;ciprofloxacin
31 Prospective, Open-Label, Noncomparative, Multicenter Study to Evaluate the Efficacy and Safety of Ciprofloxacin Extended Release (Cipro XR) 1000 mg Tablets Given Once Daily for 7 to 14 Days in the Treatment of Patients 18 Years or Older With Complicated Urinary Tract Infections Caused by Pseudomonas Aeruginosa and Other Common Uropathogens Completed NCT00481689 Phase 4 Cipro XR (Ciprofloxacin, BAYQ3939)
32 Reducing Antibiotic Use for Uncomplicated Urinary Tract Infection in General Practice by Treatment With Uva Ursi (UU)- a Comparative Effectiveness Trial Completed NCT03151603 Phase 4 Arctuvan;Fosfomycin;Placebo to Arctuvan;Placebo to Fosfomycin
33 Immediate vs. Conditional Use of Antibiotics in Uncomplicated Urinary Tract Infection (UTI) - a Comparative Effectiveness Study in General Practice (ICUTI) Completed NCT01488955 Phase 4 Ibuprofen;Fosfomycin-Trometamol
34 Does Prophylaxis With Macrobid Reduce the Incidence of Urinary Tract Infection in Patients Who Receive a Sub-Urethral Sling for the Treatment of Stress Urinary Incontinence: Randomized, Double Blinded Placebo Controlled Clinical Trial Completed NCT00734968 Phase 4 Nitrofurantoin
35 A Randomized, Multicenter, Parallel Group Study to Evaluate Safety and Efficacy of a Weekly Oral Cyclic Antibiotic Programme in the Prevention of Urinary Tract Infection on Neurological Bladder Completed NCT01388413 Phase 4 Weekly Oral Cyclic Antibiotic programme
36 Relevance of Biomarkers and Clinical Predictors of Outcome in Unselected Population With Febrile Urinary Tract Infection at Primary Care and Emergency Department in a Prospective, Randomized Cohort Trial Comparing Short (7 Days) Antibiotic Treatment With Conventional Treatment (14 Days) Completed NCT00809913 Phase 4 short treatment (ciprofloxacin)
37 The Bacteriuria in Renal Transplantation (BiRT) Study: A Prospective, Randomized, Parallel-group, Multicenter, Open-label, Superiority Trial Comparing Antibiotics Versus no Treatment in the Prevention of Symptomatic Urinary Tract Infection in Kidney Transplant Recipients With Asymptomatic Bacteriuria Completed NCT01871753 Phase 4
38 A Randomized, Controlled, Multicentre Trial of Collateral Damage on the Intestinal Microbiota Inferred by Temocillin Versus Cefotaxime in Patients Receiving Empirical Treatment for Febrile Urinary Tract Infections Completed NCT02959957 Phase 4 Temocillin;Cefotaxime
39 Nitrofurantoin Administration for the Prevention of Short-Term Catheter Associated Urinary Tract Infection After Pelvic Surgery (NAUTICA): A Randomized Controlled Trial Completed NCT03287089 Phase 4 Nitrofurantoin 100 MG;Placebo Oral Tablet
40 A Prospective Study on the Usage Patterns of Doripenem in the Asia Pacific Region Completed NCT00986102 Phase 4 doripenem
41 Antibiotic Prophylaxis for Urinary Tract Infection in Patients Requiring Catheterization After Urogynecologic Surgery Completed NCT01450800 Phase 4 Nitrofurantoin;Placebo
42 EXPRESS: Evaluating Cipro XR Patient Response, Education, Safety, and Satisfaction Completed NCT00663806 Phase 4
43 Randomized Controled Multicentric Trial, of Non Inferiority, Comparing Two Durations of Antibiotherapy (5 Days Versus 10 Days) in COMMUNAUTARY Acute Uncomplicated Pyelonephritis. Completed NCT00873626 Phase 4 levofloxacin, ciprofloxacin and ofloxacin (fluoroquinolones)
44 Recurrent Urinary Tract Infections in Children: Bacterial Identification, Antibiotic Susceptibility Profiling and Cytokine Levels Associated With Antibiotic Prophylaxis Completed NCT02357758 Phase 4 Antibiotic Prophylaxis
45 Fosfomycin-Trometamol in Urinary Tract Infection Prophylaxis After Kidney Transplantation. Randomized Controlled Trial. Completed NCT01820897 Phase 4 Fosfomycin-Trometamol;Sulfamethoxazole trimethoprim
46 Antibiotic Treatment for Intermittent Bladder Catheterisation: A Randomised Controlled Trial of Once Daily Prophylaxis Completed NCT02145338 Phase 4 Nitrofurantoin or Trimethoprim or Cefalexin
47 A Randomized, Double-blind, Placebo-controlled Trial of Nitrofurantoin Prophylaxis During Catheterization for Acute Postoperative Urinary Retention After Pelvic Reconstructive Surgery Completed NCT02727322 Phase 4 Nitrofurantoin;Placebo
48 Perioperative Disodium Fosfomycin in the Prophylaxis of Urinary Tract Infection in Kidney Transplant Recipients. Controlled Clinical Trial (PERIFOS Trial) Completed NCT03235947 Phase 4 Fosfomycin disodium;Trimethoprim / Sulfamethoxazole;Intravenous placebo
49 The EDGE Consortium: A Randomized Trial of Preoperative Prophylactic Antibiotics Prior to Percutaneous Nephrolithotomy: Part 1 Completed NCT02384200 Phase 4 nitrofurantoin monohydrate/macrocrystalline capsules;ampicillin;gentamicin;vancomycin;ceftriaxone
50 A Post Marketing Surveillance Study on the Safety and Effectiveness of Doripenem in the Therapy of Thai Patients With Nosocomial Pneumonia, Complicated Intra-Abdominal Infections and Complicated Urinary Tract Infections Completed NCT00965848 Phase 4 Doripenem

Search NIH Clinical Center for Acute Cystitis

Inferred drug relations via UMLS 71 / NDF-RT 50 :


acetohydroxamic acid
acetyl sulfisoxazole
Cinoxacin
Ciprofloxacin
Enoxacin
gemifloxacin mesylate
GENTAMICIN SULFATE PWDR
lomefloxacin
Methylene blue
Nitrofurantoin
NITROFURANTOIN, MACROCRYSTALS
Sulfamethizole
Sulfisoxazole
Sulfisoxazole Diolamine
TRIMETHOPRIM SULFATE

Genetic Tests for Acute Cystitis

Anatomical Context for Acute Cystitis

MalaCards organs/tissues related to Acute Cystitis:

40
Kidney, Prostate, Spinal Cord, Testes, Colon, Liver, Neutrophil

Publications for Acute Cystitis

Articles related to Acute Cystitis:

(show top 50) (show all 22540)
# Title Authors PMID Year
1
Emphysematous cystitis as a rare form of urinary tract infection. 61 42
31697263 2019
2
Pediatric Genitourinary Infections and Other Considerations. 42
31563205 2019
3
Antimicrobial susceptibility among urinary Escherichia coli isolates from female outpatients: age-related differences. 42
31580562 2019
4
Polyethyleneimine-Functionalized Magnetic Fe₃O₄ and Nanodiamond Particles as a Platform for Amoxicillin Delivery. 61
31968409 2020
5
Prevalence and Clinical Characteristics of Asymptomatic Pyuria in Chronic Kidney Disease. 61
31858764 2020
6
Possible risk factors for acute and chronic deep periprosthetic joint infections in primary total knee arthroplasty. Do BMI, smoking, urinary tract infections, gender, and ASA classification have an impact? 61
32025115 2020
7
Consequences of unintended pregnancy on mother and fetus and newborn in North-East of Iran. 61
30196738 2020
8
Laboratory Findings After Urinary Tract Infection and Antimicrobial Prophylaxis in Children With Vesicoureteral Reflux. 61
31888378 2020
9
Fosfomycin for treatment of multidrug-resistant pathogens causing urinary tract infection. 61
31859021 2020
10
A clinical approach to multidrug-resistant urinary tract infection and subclinical bacteriuria in dogs and cats. 61
31707934 2020
11
Educational review: role of the pediatric nephrologists in the work-up and management of kidney stones. 61
30607567 2020
12
Trends in Health Care-Associated Infection Prevention Practices in US Veterans Affairs Hospitals From 2005 to 2017. 61
32022877 2020
13
Surveillance of common infections in the early period after renal transplantation in a national centre: 2014 - 2017. 61
32037682 2020
14
Computed tomographic excretory urography for diagnosing ectopic ureter in a female rhesus macaque (Macaca mulatta). 61
31657019 2020
15
Nano-lantern on paper for smartphone-based ATP detection. 61
31786021 2020
16
Pediatric Kidney Transplantation Outcomes in Children with Primary Urological Abnormalities Versus Nonurological Abnormalities: Long-Term Results. 61
31487221 2020
17
Comparing benign laparoscopic and abdominal hysterectomy outcomes by time. 61
31098703 2020
18
Accuracy of catheter-associated urinary tract infections reported to the National Healthcare Safety Network, January 2010 through July 2018. 61
31326261 2020
19
Considerations in the Selection of Renal Dosage Adjustments for Patients with Serious Infections: Lessons Learned from the Development of Ceftazidime-Avibactam. 61
32015049 2020
20
Circulating mucosal-associated invariant T cells in subjects with recurrent urinary tract infections are functionally impaired. 61
32032475 2020
21
Implementation of a standardized voiding management protocol to reduce unnecessary re-catheterization - A quality improvement project. 61
32033800 2020
22
Corrigendum to "Physiologically-Based Pharmacokinetic model for Ciprofloxacin in children with complicated Urinary Tract Infection" [European Journal of Pharmaceutical Sciences 128 (2019) 171-179]. 61
31870584 2020
23
Antimicrobial stewardship in diabetic ketoacidosis: a single-centre experience. 61
31059195 2020
24
Abnormal Intestinal Microbiome in Medical Disorders and Potential Reversibility by Fecal Microbiota Transplantation. 61
32008133 2020
25
Effects of sodium-glucose co-transporter-2 inhibitors in type 2 diabetes in women versus men. 61
31486272 2020
26
Comparative Study of Retroperitoneal Laparoscopic Versus Open Ipsilateral Nephrectomy After Percutaneous Nephrostomy: A Multicenter Analysis. 61
32027216 2020
27
Review of Imaging Findings in Urinary Tract Infections. 61
31964498 2020
28
Thrombotic microangiopathy and liver toxicity due to a combination therapy of leflunomide and methotrexate: a case report. 61
32019572 2020
29
Association of Cough Status With Bacterial Infections in Febrile Infants. 61
31915133 2020
30
Multiplex PCR Based Urinary Tract Infection (UTI) Analysis Compared to Traditional Urine Culture in Identifying Significant Pathogens in Symptomatic Patients. 61
31715272 2020
31
How Accurate Are the Surgical Risk Preoperative Assessment System (SURPAS) Universal Calculators in Total Joint Arthroplasty? 61
31904684 2020
32
Updated Italian recommendations for the diagnosis, treatment and follow-up of the first febrile urinary tract infection in young children. 61
31454101 2020
33
Aminoglycoside versus carbapenem or piperacillin/tazobactam treatment for bloodstream infections of urinary source caused by Gram-negative ESBL-producing Enterobacteriaceae. 61
31691817 2020
34
Risk factors for febrile urinary tract infections in the first year after pediatric renal transplantation. 61
31880402 2020
35
Evaluation and Treatment of Overactive Bladder in Women. 61
32029089 2020
36
Impact of Prolonged Skeletal Traction in Patients With Acetabular Fractures. 61
31567697 2020
37
Clinical characteristics and outcome of childhood vesicoureteral reflux. 61
31984697 2020
38
Distribution of virulence genes and phylogenetics of uropathogenic Escherichia coli among urinary tract infection patients in Addis Ababa, Ethiopia. 61
32033541 2020
39
Outcomes of Empirical Antimicrobial Therapy for Pediatric Community-onset Febrile Urinary Tract Infection in the Era of Increasing Antimicrobial Resistance. 61
31738320 2020
40
Pregnancy outcome after first-trimester exposure to fosfomycin for the treatment of urinary tract infection: an observational cohort study. 61
31302868 2020
41
Profiles of the bacterial community in short-term indwelling urinary catheters by duration of catheterization and subsequent urinary tract infection. 61
31540834 2020
42
Effect of Vaginal Lactobacillus Species on Escherichia coli Growth. 61
31990804 2020
43
Plazomicin for treating complicated urinary tract infection. 61
31711798 2020
44
Health Care-Associated Infection in Solid Organ Transplant Recipients. 61
32035674 2020
45
Non-invasive techniques for stimulating urine production in non-toilet trained children: a systematic review. 61
32033959 2020
46
[Preoperative PSA levels and development of PSA after 180-W XPS greenlight laser treatment of the prostate: what is the reality in clinical routine practice?] 61
32018334 2020
47
Evaluating the July Effect in Oral and Maxillofacial Surgery: Part I-Mandibular Fractures. 61
31491417 2020
48
It is efficient to monitor the status of implanted ureteral stent using a mobile social networking service application. 61
30877315 2020
49
Prolonged use of spinal precautions is associated with increased morbidity in the trauma patient. 61
31917010 2020
50
Prestroke Disability Predicts Adverse Poststroke Outcome: A Registry-Based Prospective Cohort Study of Acute Stroke. 61
31842700 2020

Variations for Acute Cystitis

Expression for Acute Cystitis

Search GEO for disease gene expression data for Acute Cystitis.

Pathways for Acute Cystitis

Pathways related to Acute Cystitis according to GeneCards Suite gene sharing:

(show all 17)
# Super pathways Score Top Affiliating Genes
1
Show member pathways
13.9 VIM UBAC1 TLR4 LCN2 INS IL6
2
Show member pathways
12.66 VIM TLR4 IL6 IL18 CCL2
3
Show member pathways
12.24 IL6 IL18 CXCL1 CCR6 CCL2
4
Show member pathways
12.23 INS IL6 CRP CCL2 ALB
5
Show member pathways
12.18 LCN2 IL6 CXCL1 CCL2
6 12.09 TLR4 IL6 IL18 CXCL1 CCL2
7 11.96 VIM INS IL6 ALB
8 11.9 TLR4 IL6 IL18 CCL2
9 11.68 TLR4 IL6 IL18 CXCL1
10 11.63 VIM TLR4 IL6 CXCL1 CCL2
11 11.61 IL6 IL18 CXCL1 CCL2
12 11.46 TLR4 IL6 IL18 CXCL1
13 11.41 VIM LCN2 IL6 IL18 CCL2
14 11.37 TLR4 IL6 IL18 CCL2
15 11.31 IL6 IL18 CXCL1 CCL2
16 11.24 TLR4 KLK3 IL18 CCL2
17 10.99 TLR4 IL6 IL18 CXCL1 CCL2

GO Terms for Acute Cystitis

Cellular components related to Acute Cystitis according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 extracellular exosome GO:0070062 9.81 VIM UPK1A UMOD UBAC1 SLC5A2 LCN2
2 extracellular space GO:0005615 9.61 LCN2 KLK3 INS IL6 IL18 CXCL1
3 extracellular region GO:0005576 9.32 UMOD LCN2 KLK3 INS IL6 IL18

Biological processes related to Acute Cystitis according to GeneCards Suite gene sharing:

(show all 16)
# Name GO ID Score Top Affiliating Genes
1 cellular protein metabolic process GO:0044267 9.83 KLK3 INS IL6 ALB
2 immune response GO:0006955 9.8 TLR4 IL6 IL18 CXCL1 CCR6 CCL2
3 positive regulation of NF-kappaB transcription factor activity GO:0051092 9.73 TLR4 INS IL6 IL18
4 inflammatory response GO:0006954 9.73 TLR4 IL6 IL18 CXCL1 CRP CCL2
5 chemokine-mediated signaling pathway GO:0070098 9.69 CXCL1 CCR6 CCL2
6 humoral immune response GO:0006959 9.65 IL6 CCR6 CCL2
7 cytokine-mediated signaling pathway GO:0019221 9.63 VIM LCN2 IL6 IL18 CXCL1 CCL2
8 acute-phase response GO:0006953 9.58 INS IL6 CRP
9 positive regulation of neuroinflammatory response GO:0150078 9.56 IL6 IL18
10 negative regulation of blood vessel diameter GO:0097756 9.55 INS CRP
11 T-helper 1 type immune response GO:0042088 9.54 TLR4 IL18
12 lipopolysaccharide-mediated signaling pathway GO:0031663 9.54 TLR4 IL18 CCL2
13 positive regulation of gene expression GO:0010628 9.5 VIM TLR4 LCN2 INS IL6 IL18
14 negative regulation of lipid storage GO:0010888 9.49 IL6 CRP
15 negative regulation of protein oligomerization GO:0032460 9.46 INS ALB
16 cellular response to lipopolysaccharide GO:0071222 9.1 VIM TLR4 LCN2 IL6 CXCL1 CCL2

Molecular functions related to Acute Cystitis according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 cytokine activity GO:0005125 9.46 IL6 IL18 CXCL1 CCL2
2 glucose:sodium symporter activity GO:0005412 8.96 SLC5A4 SLC5A2
3 enterobactin binding GO:1903981 8.62 LCN2 ALB

Sources for Acute Cystitis

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
17 EFO
18 ExPASy
19 FMA
28 GO
29 GTR
30 HMDB
31 HPO
32 ICD10
33 ICD10 via Orphanet
34 ICD9CM
35 IUPHAR
36 KEGG
37 LifeMap
39 LOVD
41 MedGen
43 MeSH
44 MESH via Orphanet
45 MGI
48 NCI
49 NCIt
50 NDF-RT
53 NINDS
54 Novoseek
56 OMIM
57 OMIM via Orphanet
61 PubMed
63 QIAGEN
68 SNOMED-CT via HPO
69 TGDB
70 Tocris
71 UMLS
72 UMLS via Orphanet
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