Aliases & Classifications for Acute Cystitis

MalaCards integrated aliases for Acute Cystitis:

Name: Acute Cystitis 12 15 73
Urinary Tract Infection 12 15 73
Recurrent Urinary Tract Infection 73
Urinary Tract Infections 43

Classifications:



External Ids:

Disease Ontology 12 DOID:13148
ICD10 33 N30.0 N39.0
ICD9CM 35 595.0
NCIt 50 C26934
SNOMED-CT 68 68226007

Summaries for Acute Cystitis

MedlinePlus : 43 The urinary system is the body's drainage system for removing wastes and extra water. It includes two kidneys, two ureters, a bladder, and a urethra. Urinary tract infections (UTIs) are the second most common type of infection in the body. You may have a UTI if you notice Pain or burning when you urinate Fever, tiredness, or shakiness An urge to urinate often Pressure in your lower belly Urine that smells bad or looks cloudy or reddish Pain in your back or side below the ribs People of any age or sex can get UTIs. But about four times as many women get UTIs as men. You're also at higher risk if you have diabetes, need a tube to drain your bladder, or have a spinal cord injury. If you think you have a UTI it is important to see your doctor. Your doctor can tell if you have a UTI with a urine test. Treatment is with antibiotics. NIH: National Institute of Diabetes and Digestive and Kidney Diseases

MalaCards based summary : Acute Cystitis, also known as urinary tract infection, is related to urethral syndrome and pyuria, and has symptoms including fever, pruritus and uti symptoms. An important gene associated with Acute Cystitis is IL6 (Interleukin 6), and among its related pathways/superpathways are Toll-like Receptor Signaling Pathway and Immune response IL-23 signaling pathway. The drugs Ibuprofen and Antibiotics, Antitubercular have been mentioned in the context of this disorder. Affiliated tissues include kidney, spinal cord and testes.

Disease Ontology : 12 A cystitis characterized by a sudden onset or severe symptoms.

Wikipedia : 76 A urinary tract infection (UTI) is an infection that affects part of the urinary tract. When it affects... more...

Related Diseases for Acute Cystitis

Diseases in the Cystitis family:

Acute Cystitis Chronic Cystitis

Diseases related to Acute Cystitis via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50) (show all 379)
# Related Disease Score Top Affiliating Genes
1 urethral syndrome 32.5 BCKDHA IER3IP1 KLK3
2 pyuria 32.2 ALB BCKDHA CRP CXCL8
3 cystitis 32.1 CCL2 CRP CXCL8 IL6 UPK1A
4 autosomal dominant polycystic kidney disease 32.0 ALB CCL2 LCN2
5 bladder disease 31.9 CRP KLK3 UPK1A
6 vesicoureteral reflux 1 31.9 C16orf58 CRP MCU UPK1A
7 arthritis 30.5 CCL2 CXCL8 IL18 IL6
8 pneumonia 30.4 CCL2 CRP CXCL1 CXCL8 IL6
9 prostatitis 30.4 CXCL8 IL6 KLK3
10 bacteriuria 30.3 CCL2 CXCL8 IL6
11 urinary tract obstruction 30.3 ALB C16orf58 CCL2 KLK3
12 pyelitis 30.2 CRP CXCL8 IL6
13 kawasaki disease 30.2 ALB CCL2 CRP IL6
14 chlamydia 30.2 CRP CXCL8 IL6
15 kidney disease 30.1 ALB CCL2 CRP IL6 LCN2
16 bacterial meningitis 30.1 ALB CRP CXCL8 IL6
17 endocarditis 30.1 ALB CRP CXCL8 IL6
18 diabetic foot ulcers 30.0 CCL2 IL6
19 pyelonephritis 30.0 ALB CCL2 CRP CXCL8 IL6
20 pulmonary disease, chronic obstructive 30.0 CCL2 CRP CXCL8 IL6
21 acute cholangitis 30.0 CRP IL6
22 acute pyelonephritis 29.9 ALB CRP CXCL8 IL6
23 perinatal necrotizing enterocolitis 29.9 CRP CXCL8 IL6
24 end stage renal failure 29.9 ALB CRP IL6
25 cholangitis 29.9 ALB CRP IL6
26 bronchiolitis 29.8 CRP CXCL8 IL6
27 mastitis 29.8 ALB CXCL8 IL6
28 decubitus ulcer 29.8 ALB CRP
29 bronchitis 29.8 ALB CRP CXCL8
30 rheumatoid arthritis 29.7 CCL2 CRP CXCL1 CXCL8 IL18 IL6
31 respiratory failure 29.7 ALB CRP CXCL8
32 gastroenteritis 29.7 ALB CRP CXCL8 IL6
33 meningitis 29.7 ALB CCL2 CRP CXCL1 CXCL8 IL6
34 myeloma, multiple 29.7 ALB CRP CXCL8 IL6
35 chronic kidney failure 29.6 ALB CRP IL6 LCN2
36 diabetes mellitus, noninsulin-dependent 29.6 ALB CCL2 CRP IL18 IL6
37 body mass index quantitative trait locus 11 29.5 CCL2 CRP IL18 IL6 LCN2
38 urinary tract infections, recurrent 12.6
39 neonatal urinary tract infectious disease 11.6
40 cystitis cystica 11.4
41 prostatic hyperplasia, benign 11.3
42 klebsiella pneumonia 11.3
43 medullary sponge kidney 11.2
44 acute gonococcal cystitis 11.1
45 ectrodactyly and ectodermal dysplasia without cleft lip/palate 11.0
46 ectrodactyly, ectodermal dysplasia, and cleft lip/palate syndrome 1 11.0
47 cystinuria 11.0
48 urofacial syndrome 1 11.0
49 hypomagnesemia 3, renal 11.0
50 hyperoxaluria, primary, type i 11.0

Comorbidity relations with Acute Cystitis via Phenotypic Disease Network (PDN): (show top 50) (show all 439)


3-Hydroxyacyl-Coa Dehydrogenase Deficiency Acquired Thrombocytopenia
Active Peptic Ulcer Disease Acute Anterolateral Myocardial Infarction
Acute Conjunctivitis Acute Cor Pulmonale
Acute Kidney Failure Acute Maxillary Sinusitis
Acute Myocardial Infarction Acute Pancreatitis
Acute Sphenoidal Sinusitis Acute Vascular Insufficiency of Intestine
Adjustment Disorder Adrenal Gland Disease
Agammaglobulinemia, X-Linked Age-Related Hearing Loss
Alcohol Abuse Alcoholic Hepatitis
Alcoholic Liver Cirrhosis Alcoholic Neuropathy
Algoneurodystrophy Allergic Urticaria
Alopecia, Neurologic Defects, and Endocrinopathy Syndrome Alzheimer Disease
Amnestic Disorder Amyloidosis
Anemia, Autoimmune Hemolytic Anorexia Nervosa
Anus Cancer Anxiety
Aortic Aneurysm Aortic Atherosclerosis
Aortic Valve Disease 1 Asthma
Atrioventricular Block Atrophic Gastritis
Atypical Depressive Disorder Autonomic Nervous System Disease
Bacteremia 2 Bacterial Meningitis
Balanoposthitis Basilar Artery Insufficiency
Benign Essential Hypertension Benign Hypertensive Renal Disease
Biliary Tract Disease Bipolar Disorder
Bladder Cancer Bladder Disease
Bladder Neck Obstruction Bleeding Disorder, Platelet-Type, 11

Graphical network of the top 20 diseases related to Acute Cystitis:



Diseases related to Acute Cystitis

Symptoms & Phenotypes for Acute Cystitis

UMLS symptoms related to Acute Cystitis:


fever, pruritus, uti symptoms

Drugs & Therapeutics for Acute Cystitis

Drugs for Acute Cystitis (from DrugBank, HMDB, Dgidb, PharmGKB, IUPHAR, NovoSeek, BitterDB):

(show all 47)
# Name Status Phase Clinical Trials Cas Number PubChem Id
1
Ibuprofen Approved Phase 4 15687-27-1 3672
2 Antibiotics, Antitubercular Phase 4,Not Applicable
3 Anti-Bacterial Agents Phase 4,Phase 3,Phase 1,Not Applicable
4 Anti-Inflammatory Agents Phase 4
5 Peripheral Nervous System Agents Phase 4
6 Analgesics Phase 4
7 Anti-Infective Agents Phase 4,Phase 3,Phase 2,Phase 1,Not Applicable
8 Analgesics, Non-Narcotic Phase 4
9 Renal Agents Phase 4,Phase 2,Not Applicable
10 Antirheumatic Agents Phase 4
11 Anti-Inflammatory Agents, Non-Steroidal Phase 4
12 Anti-Infective Agents, Urinary Phase 4,Phase 2,Not Applicable
13 Cyclooxygenase Inhibitors Phase 4
14 Amdinocillin Pivoxil Phase 4
15
Ciprofloxacin Approved, Investigational Phase 3,Not Applicable 85721-33-1 2764
16
Cefditoren Approved, Investigational Phase 3 117467-28-4, 104145-95-1 9571074 9870843
17 Cytochrome P-450 Enzyme Inhibitors Phase 3,Not Applicable
18 Cytochrome P-450 CYP1A2 Inhibitors Phase 3,Not Applicable
19 Cephalosporins Phase 3
20 Cefditoren pivoxil Phase 3
21 Topoisomerase Inhibitors Phase 3,Not Applicable
22 Cranberry Approved, Investigational Phase 2,Not Applicable
23
Nitrofurantoin Approved, Vet_approved Phase 2,Not Applicable 67-20-9 5353830
24 Trimethoprim, Sulfamethoxazole Drug Combination Phase 2,Not Applicable
25
Cefpodoxime Approved, Vet_approved Not Applicable 82619-04-3, 80210-62-4 6335986
26
Ceftizoxime Approved, Investigational Not Applicable 68401-81-0 6533629
27
Zinc Approved, Investigational Not Applicable 7440-66-6
28
Trimethoprim Approved, Vet_approved Not Applicable 738-70-5 5578
29
Fosfomycin Approved Not Applicable 23155-02-4 446987
30
Sulfamethoxazole Approved Not Applicable 723-46-6 5329
31
Amoxicillin Approved, Vet_approved Not Applicable 26787-78-0 33613
32 Grape Approved Not Applicable
33
Citric Acid Approved, Nutraceutical, Vet_approved Not Applicable 77-92-9 311
34
Vitamin C Approved, Nutraceutical 50-81-7 5785 54670067
35
Riboflavin Approved, Investigational, Nutraceutical, Vet_approved 83-88-5 493570
36 Cefpodoxime proxetil Not Applicable
37 Antitubercular Agents ,Not Applicable
38 Chelating Agents Not Applicable
39 Calcium, Dietary Not Applicable
40 Acidophilus Not Applicable
41 Anticoagulants Not Applicable
42 Citrate Not Applicable
43 Vitamin B2
44 Vitamins
45 beta-Lactamase Inhibitors Not Applicable
46 Clavulanic Acids Not Applicable
47 Amoxicillin-Potassium Clavulanate Combination Not Applicable

Interventional clinical trials:

(show all 17)
# Name Status NCT ID Phase Drugs
1 Management of Urinary Tract Infections in Primary Care Facilities. Completed NCT01132131 Phase 4
2 Ibuprofen Versus Mecillinam for Uncomplicated Cystitis Completed NCT01849926 Phase 4 Ibuprofen;Mecillinam
3 Efficacy and Safety of Cefditoren Pivoxil Versus Ciprofloxacin in Acute Uncomplicated Cystitis Completed NCT00598403 Phase 3 cefditoren pivoxil;Ciprofloxacin
4 Comparison in the Treatment of Acute Cystitis Using Cephalosporin and Norfloxacin (CECI) Withdrawn NCT01527019 Phase 3 Norfloxacin;Cephalosporins;Cephalosporins
5 Effect of Adjuvant Treatment With Compound Cranberry Extract Tablets in Acute Bacterial Cystitis. Unknown status NCT00305071 Phase 2 compound cranberry extract tablet
6 Short Course Nitrofurantoin for Acute Cystitis Completed NCT00391651 Phase 2 Nitrofurantoin 100mg twice daily x 5 days;TMP/SMX DS twice daily x 3 days
7 Pharmacokinetic Study of Oral Gepotidacin (GSK2140944) in Subjects With Uncomplicated Urinary Tract Infection (Acute Cystitis) Recruiting NCT03568942 Phase 1, Phase 2 Gepotidacin
8 A Bioequivalence Study of SKF101804 Cefixime Versus Cefixime Reference Formulation in Healthy Adults Under Fasting Conditions Withdrawn NCT03329547 Phase 1 Cefixime test capsule;Cefixime reference capsule
9 Cefpodoxime vs Ciprofloxacin for Acute Cystitis Completed NCT00194532 Not Applicable Cefpodoxime;Ciprofloxacin
10 Assessment of UTI Symptoms and Quality of Life According to Antibiotics Treatment in Acute Uncomplicated Cystitis Completed NCT01631955 Ciprobay
11 Clinical Trial of L. Reuteri in Urinary Tract Infections in Non Pregnant Women Completed NCT03019172 Not Applicable
12 Epidemiology of Acute Bacterial Uncomplicated Cystitis in General Practice Completed NCT00958295
13 Observational Study With Mode of Action-Analysis of Cystorenal Cranberry Extract in Patients With Recurrent Urinary Tract Infections Recruiting NCT03019874
14 Single Dose Monurol for Treatment of Acute Cystitis Active, not recruiting NCT00976963 Not Applicable Fosfomycin;TMP/SMX DS
15 Lactobacillus Reuteri for Treatment of Uncomplicated UTI in Pregnant Women Not yet recruiting NCT03362697 Not Applicable Antibiotics
16 The Development and Testing of a Scaling Strategy for a Community-Based Primary Care Antimicrobial Stewardship Program Not yet recruiting NCT03517215 Not Applicable
17 Urell and Pregnancy Terminated NCT01818180 Not Applicable

Search NIH Clinical Center for Acute Cystitis

Inferred drug relations via UMLS 73 / NDF-RT 51 :


Genetic Tests for Acute Cystitis

Anatomical Context for Acute Cystitis

MalaCards organs/tissues related to Acute Cystitis:

41
Kidney, Spinal Cord, Testes, Prostate, Liver, Colon, Skin

Publications for Acute Cystitis

Articles related to Acute Cystitis:

(show top 50) (show all 1502)
# Title Authors Year
1
Urinary tract infection with rare pathogen Raoultella Planticola: A post-operative case and review. ( 30479967 )
2019
2
Efficacy and Safety of Plazomicin Compared with Levofloxacin in the Treatment of Complicated Urinary Tract Infection and Acute Pyelonephritis: A Multicenter, Randomized, Double-Blind, Phase 2 Study. ( 29378708 )
2018
3
Interpretation of pyuria in children with urinary tract infection. ( 29143990 )
2018
4
Hyperammonemia associated with distal renal tubular acidosis or urinary tract infection: a systematic review. ( 29134448 )
2018
5
Identification through MALDI-TOF mass spectrometry and antimicrobial susceptibility profiling of bacterial pathogens isolated from sow urinary tract infection. ( 29090643 )
2018
6
D-dimer as a marker of acute pyelonephritis in infants younger than 24A months with urinary tract infection. ( 29306986 )
2018
7
Reevaluation of the Acute Cystitis Symptom Score, a Self-Reporting Questionnaire. Part II. Patient-Reported Outcome Assessment. ( 29883423 )
2018
8
Testing an association between TLR4 and CXCR1 gene polymorphisms with susceptibility to urinary tract infection in type 2 diabetes in north Indian population. ( 29066305 )
2018
9
Xanthogranulomatous Pyelonephritis: A Complicated Febrile Urinary Tract Infection Detected by Point-of-Care Ultrasound in the Emergency Department. ( 29753570 )
2018
10
Asymptomatic bacteriuria and urinary tract infection in pregnant women with and without diabetes: Cohort study. ( 29338897 )
2018
11
The role of the Acute Cystitis Symptom Score questionnaire for research and antimicrobial stewardship. Validation of the Hungarian version. ( 29732220 )
2018
12
Neuroepithelial control of mucosal inflammation in acute cystitis. ( 30030504 )
2018
13
An infected thoracoabdominal aortic aneurysm mimicking the symptoms of urinary tract infection: A case report. ( 29204357 )
2018
14
Microscopic Bacteriuria Detected by Automated Urinalysis for the Diagnosis of Urinary Tract Infection. ( 30172436 )
2018
15
Predictors of Symptom Duration and Bacteriuria in Uncomplicated Urinary Tract Infection. ( 30175647 )
2018
16
When Asymptomatic Bacteriuria is not Asymptomatic or "Pseudo-Urinary Tract Infection". ( 30289984 )
2018
17
Reply to: When Asymptomatic Bacteriuria Is Not Asymptomatic or "Pseudo-Urinary Tract Infection". ( 30289985 )
2018
18
Effects of the use of silver-coated urinary catheters on the incidence of catheter-associated bacteriuria and urinary tract infection in dogs. ( 30398417 )
2018
19
Prevalence and antimicrobial sensitivity pattern of urinary tract infection among children with cerebral palsy, Moshi, Tanzania. ( 29774893 )
2018
20
Contribution of yersiniabactin to the virulence of an Escherichia coli sequence type 69 ("clonal group A") cystitis isolate in murine models of urinary tract infection and sepsis. ( 29702209 )
2018
21
Hyperammonemic encephalopathy with septic shock caused by obstructive urinary tract infection. ( 30191129 )
2018
22
Cardiogenic and septic shock associated with aortic and mitral valve infective endocarditis caused by Abiotrophia Defectiva from a urinary tract infection. ( 30023056 )
2018
23
A Rare Case of Tricuspid Valve Endocarditis Caused by Enterococcus Gallinarum in a Patient with Recurrent Urinary Tract Infection. ( 29512472 )
2018
24
Infective endocarditis following urinary tract infection caused by Globicatella sanguinis. ( 29255675 )
2018
25
Recurrent Guillain-Barré Syndrome Following Urinary Tract Infection by Escherichia coli. ( 29318796 )
2018
26
Nontypable Haemophilus influenzae Septicemia and Urinary Tract Infection Associated with Renal Stone Disease. ( 30197697 )
2018
27
Hemolytic-uremic syndrome after Escherichia coli urinary tract infection in humans: systematic review of the literature. ( 30328581 )
2018
28
Risks of irritable bowel syndrome in children with infantile urinary tract infection: a 13-year nationwide cohort study. ( 29588332 )
2018
29
Differentiating Kawasaki disease from urinary tract infection in febrile children with pyuria and C-reactive protein elevation. ( 30454066 )
2018
30
The frequency of Klebsiella pneumonia encoding genes for CTX-M, TEM-1 and SHV-1 extended-spectrum beta lactamases enzymes isolated from urinary tract infection. ( 29433582 )
2018
31
Altered methotrexate clearance in the treatment of CNS lymphoma with concurrent use of nitrofurantoin for a urinary tract infection. ( 30486745 )
2018
32
Escherichia coli isolates from commercial chicken meat and eggs cause sepsis, meningitis and urinary tract infection in rodent models of human infections. ( 28703468 )
2018
33
Renal Mucormycosis: A Rare Cause of Urinary Tract Infection Leading to End-stage Renal Disease (ESRD). ( 30252109 )
2018
34
Urinary Tract Infection in Children With Nephrotic Syndrome. ( 28827494 )
2018
35
Penicillin allergy and association with ciprofloxacin coverage in community-onset urinary tract infection. ( 30033886 )
2018
36
Antepartum urinary tract infection and postpartum depression in Taiwan - a nationwide population-based study. ( 29587654 )
2018
37
Population Pharmacokinetic Analysis of Cefiderocol, a Parenteral Siderophore Cephalosporin, in Healthy Subjects, Subjects with Various Degrees of Renal Function, and Patients with Complicated Urinary Tract Infection or Acute Uncomplicated Pyelonephritis. ( 29038272 )
2018
38
The efficacy and safety of tazobactam/ceftolozane in Japanese patients with uncomplicated pyelonephritis and complicated urinary tract infection. ( 30420153 )
2018
39
Case of acute paraspinal pyomyositis in an elderly diabetic secondary to spread from urinary tract infection. ( 30139787 )
2018
40
Change in urodynamic pattern and incidence of urinary tract infection in patients with traumatic spinal cord injury practicing clean self-intermittent catheterization. ( 30277852 )
2018
41
Prenatal complicated duplex collecting system and ureterocele-Important risk factors for urinary tract infection. ( 28532765 )
2018
42
Use of the MALDI BioTyper system and rapid BACpro with MALDI-TOF MS for rapid identification of microorganisms causing bacterial urinary tract infection in feline urine samples. ( 30089741 )
2018
43
Predominant bacteria and patterns of antibiotic susceptibility in urinary tract infection in children with spina bifida. ( 29709445 )
2018
44
Systematic review and practice policy statements on urinary tract infection prevention in adults with spina bifida. ( 29928619 )
2018
45
The association between urinary tract infection during pregnancy and preeclampsia: A meta-analysis. ( 30200124 )
2018
46
Prediction of vesicoureteral reflux in children with febrile urinary tract infection using relative uptake and cortical defect in DMSA scan. ( 29576374 )
2018
47
Long-term Outcomes of Endoscopic Anti-reflux Surgery in Pediatric Patients with Vesicoureteral Reflux: Urinary Tract Infection, Renal Scarring, and Predictive Factors for Success. ( 30224908 )
2018
48
Vesicoureteral Reflux and Renal Scarring in Infants After the First Febrile Urinary Tract Infection. ( 30514993 )
2018
49
Re: Incidence of Urinary Tract Infection among Siblings of Children with Vesicoureteral Reflux. ( 29310156 )
2018
50
Re: Computer Model Predicting Breakthrough Febrile Urinary Tract Infection in Children with Primary Vesicoureteral Reflux. ( 29357577 )
2018

Variations for Acute Cystitis

Expression for Acute Cystitis

Search GEO for disease gene expression data for Acute Cystitis.

Pathways for Acute Cystitis

Pathways related to Acute Cystitis according to GeneCards Suite gene sharing:

(show all 24)
# Super pathways Score Top Affiliating Genes
1
Show member pathways
12.87 CCL2 CXCL1 CXCL8 IL18 IL6 MCU
2
Show member pathways
12.45 CCL2 CXCL1 IL18 IL6
3
Show member pathways
12.19 ALB CCL2 CRP IL6
4
Show member pathways
12.16 CCL2 CXCL1 CXCL8 IL6 LCN2
5 11.87 CCL2 CXCL1 CXCL8 IL6
6
Show member pathways
11.85 CCL2 CXCL1 CXCL8
7 11.82 CCL2 CXCL1 IL6
8 11.8 CXCL1 CXCL8 IL6
9 11.76 CCL2 CXCL8 IL6
10 11.74 CXCL1 CXCL8 IL6
11
Show member pathways
11.72 CXCL1 CXCL8 IL6
12 11.71 CXCL1 CXCL8 IL18 IL6
13 11.61 CCL2 CXCL8 IL18 IL6 LCN2
14 11.56 CCL2 CXCL1 IL18 IL6
15 11.52 CCL2 CXCL8 IL6
16 11.38 CCL2 IL18 KLK3
17 11.36 CXCL1 CXCL8 IL18 IL6
18 11.31 CCL2 CXCL1 CXCL8 IL18 IL6
19 11.25 CCL2 CXCL8 IL18 IL6
20 11.22 CCL2 CXCL8 IL6
21 11 CCL2 CXCL1 CXCL8 IL18 IL6
22 10.91 CRP CXCL8 IL6
23 10.87 CCL2 CXCL1 CXCL8 IL18 IL6
24 10.71 CCL2 CXCL1 CXCL8 IL18 IL6

GO Terms for Acute Cystitis

Cellular components related to Acute Cystitis according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 extracellular region GO:0005576 9.61 ALB CCL2 CRP CXCL1 CXCL8 IL18
2 extracellular space GO:0005615 9.28 ALB CCL2 CRP CXCL1 CXCL8 IL18

Biological processes related to Acute Cystitis according to GeneCards Suite gene sharing:

(show all 12)
# Name GO ID Score Top Affiliating Genes
1 immune response GO:0006955 9.83 CCL2 CXCL1 CXCL8 IL18 IL6
2 regulation of signaling receptor activity GO:0010469 9.72 CCL2 CXCL1 CXCL8 IL18 IL6
3 neutrophil chemotaxis GO:0030593 9.67 CCL2 CXCL1 CXCL8
4 cellular response to interleukin-1 GO:0071347 9.63 CCL2 CXCL8 LCN2
5 inflammatory response GO:0006954 9.63 CCL2 CRP CXCL1 CXCL8 IL18 IL6
6 chemokine-mediated signaling pathway GO:0070098 9.54 CCL2 CXCL1 CXCL8
7 PERK-mediated unfolded protein response GO:0036499 9.51 CCL2 CXCL8
8 neutrophil activation GO:0042119 9.48 CXCL8 IL18
9 negative regulation of lipid storage GO:0010888 9.4 CRP IL6
10 cellular response to lipopolysaccharide GO:0071222 9.35 CCL2 CXCL1 CXCL8 IL6 LCN2
11 positive regulation of neuroinflammatory response GO:0150078 9.26 IL18 IL6
12 cytokine-mediated signaling pathway GO:0019221 9.1 CCL2 CXCL1 CXCL8 IL18 IL6 LCN2

Molecular functions related to Acute Cystitis according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 chemokine activity GO:0008009 9.13 CCL2 CXCL1 CXCL8
2 cytokine activity GO:0005125 9.02 CCL2 CXCL1 CXCL8 IL18 IL6

Sources for Acute Cystitis

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
17 ExPASy
19 FMA
28 GO
29 GTR
30 HGMD
31 HMDB
32 HPO
33 ICD10
34 ICD10 via Orphanet
35 ICD9CM
36 IUPHAR
37 KEGG
38 LifeMap
40 LOVD
42 MedGen
44 MeSH
45 MESH via Orphanet
46 MGI
49 NCI
50 NCIt
51 NDF-RT
54 NINDS
55 Novoseek
57 OMIM
58 OMIM via Orphanet
62 PubMed
64 QIAGEN
69 SNOMED-CT via HPO
70 SNOMED-CT via Orphanet
71 TGDB
72 Tocris
73 UMLS
74 UMLS via Orphanet
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