Aliases & Classifications for Acute Cystitis

MalaCards integrated aliases for Acute Cystitis:

Name: Acute Cystitis 12 15 72 33
Urinary Tract Infection 12 17 72
Urinary Tract Infections 43 15
Recurrent Urinary Tract Infection 72

Classifications:



External Ids:

Disease Ontology 12 DOID:13148
ICD9CM 35 595.0
NCIt 50 C26934
SNOMED-CT 68 68226007
ICD10 33 N30.0 N39.0
UMLS 72 C0042029 C0149523 C0262655

Summaries for Acute Cystitis

MedlinePlus : 43 The urinary system is the body's drainage system for removing wastes and extra water. It includes two kidneys, two ureters, a bladder, and a urethra. Urinary tract infections (UTIs) are the second most common type of infection in the body. You may have a UTI if you notice Pain or burning when you urinate Fever, tiredness, or shakiness An urge to urinate often Pressure in your lower belly Urine that smells bad or looks cloudy or reddish Pain in your back or side below the ribs People of any age or sex can get UTIs. But about four times as many women get UTIs as men. You're also at higher risk if you have diabetes, need a tube to drain your bladder, or have a spinal cord injury. If you think you have a UTI it is important to see your doctor. Your doctor can tell if you have a UTI with a urine test. Treatment is with antibiotics. NIH: National Institute of Diabetes and Digestive and Kidney Diseases

MalaCards based summary : Acute Cystitis, also known as urinary tract infection, is related to cystitis and urinary tract obstruction, and has symptoms including fever, pruritus and uti symptoms. An important gene associated with Acute Cystitis is IL6 (Interleukin 6), and among its related pathways/superpathways are Toll-like Receptor Signaling Pathway and IL-17 Family Signaling Pathways. The drugs acetic acid and Apricot have been mentioned in the context of this disorder. Affiliated tissues include kidney, prostate and spinal cord, and related phenotypes are Decreased viability in esophageal squamous lineage and adipose tissue

Disease Ontology : 12 A cystitis characterized by a sudden onset or severe symptoms.

Wikipedia : 75 A urinary tract infection (UTI) is an infection that affects part of the urinary tract. When it affects... more...

Related Diseases for Acute Cystitis

Diseases in the Cystitis family:

Acute Cystitis Chronic Cystitis

Diseases related to Acute Cystitis via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50) (show all 741)
# Related Disease Score Top Affiliating Genes
1 cystitis 32.0 UPK1A UMOD TLR4 IL6 CXCL8 CRP
2 urinary tract obstruction 32.0 UMOD CCL2 ALB
3 end stage renal failure 31.5 UMOD IL6 CRP ALB
4 toxic shock syndrome 31.5 TLR4 IL6 CXCL8
5 interstitial cystitis 31.4 UMOD IL6 CXCL8
6 pyelitis 31.2 TLR4 IL6 CXCL8 CRP
7 chlamydia 31.2 TLR4 IL6 CXCL8 CRP
8 interstitial nephritis 31.1 UMOD CRP ALB
9 endocarditis 31.1 IL6 CXCL8 CRP ALB
10 bronchitis 31.1 CXCL8 CRP ALB
11 gastroenteritis 31.1 IL6 CXCL8 CRP ALB
12 salmonellosis 31.1 TLR4 IL18 ALB
13 acute kidney tubular necrosis 31.0 UMOD IL18 ALB
14 pyuria 31.0 CXCL8 CRP ALB
15 septic arthritis 31.0 TLR4 CXCL8 CRP
16 bacteriuria 30.9 UMOD TLR4 IL6 CXCL8 CCL2
17 arthritis 30.9 IL6 IL18 CXCL8 CCL2
18 cytomegalovirus infection 30.9 IL6 CXCL8 CCL2
19 kawasaki disease 30.8 IL6 CRP CCL2 ALB
20 otitis media 30.8 TLR4 IL6 CXCL8 ALB
21 acute pyelonephritis 30.8 IL6 CXCL8 CRP ALB
22 peritonitis 30.8 IL6 CXCL8 CRP CCL2 ALB
23 cholangitis 30.8 IL6 CRP ALB
24 pelvic inflammatory disease 30.7 TLR4 CRP CCL2
25 bronchiolitis 30.7 TLR4 IL6 CXCL8 CRP
26 peripheral vascular disease 30.7 IL6 CRP ALB
27 anterior uveitis 30.6 TLR4 IL6 CCL2
28 bacterial sepsis 30.6 TLR4 CXCL8 CRP
29 respiratory failure 30.6 CXCL8 CRP ALB
30 pulmonary disease, chronic obstructive 30.6 IL6 CXCL8 CRP CCL2
31 perinatal necrotizing enterocolitis 30.6 TLR4 IL6 CXCL8 CRP
32 melioidosis 30.5 TLR4 IL6 IL18
33 nervous system disease 30.5 IL6 CRP CCL2 ALB
34 arteriosclerosis 30.5 TLR4 IL6 CRP CCL2
35 typhoid fever 30.5 TLR4 IL6 CRP ALB
36 pleurisy 30.5 CXCL8 CRP CCL2
37 nutritional deficiency disease 30.5 IL6 CRP ALB
38 appendicitis 30.4 IL6 CXCL8 CRP ALB
39 bacterial vaginosis 30.4 TLR4 IL6 CXCL8
40 vulvovaginitis 30.4 SLC5A2 CXCL8
41 mastitis 30.4 IL6 CXCL8 ALB
42 vascular disease 30.4 IL6 CRP CCL2 ALB
43 endometriosis 30.4 IL6 CXCL8 CCL2
44 inflammatory bowel disease 30.4 TLR4 IL6 IL18 CXCL8 CRP
45 pneumonia 30.3 TLR4 IL6 CXCL8 CXCL1 CRP CCL2
46 viral meningitis 30.3 IL6 CXCL8 CRP CCL2
47 kidney disease 30.3 UMOD LCN2 IL6 CRP CCL2 ALB
48 bacterial meningitis 30.2 IL6 CXCL8 CRP ALB
49 bacterial infectious disease 30.1 TLR4 IL6 IL18 CXCL8 CRP CCL2
50 pyelonephritis 30.1 UMOD TLR4 IL6 CXCL8 CRP CCL2

Comorbidity relations with Acute Cystitis via Phenotypic Disease Network (PDN): (show top 50) (show all 426)


3-Hydroxyacyl-Coa Dehydrogenase Deficiency Acquired Thrombocytopenia
Active Peptic Ulcer Disease Acute Anterolateral Myocardial Infarction
Acute Conjunctivitis Acute Cor Pulmonale
Acute Kidney Failure Acute Maxillary Sinusitis
Acute Myocardial Infarction Acute Pancreatitis
Acute Sphenoidal Sinusitis Acute Vascular Insufficiency of Intestine
Adjustment Disorder Adrenal Gland Disease
Agammaglobulinemia, X-Linked Age-Related Hearing Loss
Alcoholic Hepatitis Alcoholic Liver Cirrhosis
Alcoholic Neuropathy Algoneurodystrophy
Allergic Urticaria Alopecia, Neurologic Defects, and Endocrinopathy Syndrome
Alzheimer Disease Amnestic Disorder
Amyloidosis Anemia, Autoimmune Hemolytic
Anorexia Nervosa Anus Cancer
Anxiety Aortic Aneurysm
Aortic Atherosclerosis Aortic Valve Disease 1
Asthma Atrioventricular Block
Atrophic Gastritis Atypical Depressive Disorder
Autonomic Nervous System Disease Bacteremia 2
Bacterial Meningitis Balanoposthitis
Basilar Artery Insufficiency Benign Essential Hypertension
Benign Hypertensive Renal Disease Biliary Tract Disease
Bipolar Disorder Bladder Cancer
Bladder Disease Bladder Neck Obstruction
Bleeding Disorder, Platelet-Type, 11 Blepharitis

Graphical network of the top 20 diseases related to Acute Cystitis:



Diseases related to Acute Cystitis

Symptoms & Phenotypes for Acute Cystitis

UMLS symptoms related to Acute Cystitis:


fever, pruritus, uti symptoms

GenomeRNAi Phenotypes related to Acute Cystitis according to GeneCards Suite gene sharing:

26
# Description GenomeRNAi Source Accession Score Top Affiliating Genes
1 Decreased viability in esophageal squamous lineage GR00235-A 9.32 CD248 CXCL1 GPR182 IL18 IL6 NHS

MGI Mouse Phenotypes related to Acute Cystitis:

46
# Description MGI Source Accession Score Top Affiliating Genes
1 adipose tissue MP:0005375 9.1 IL18 IL6 LCN2 SLC5A2 TLR4 UMOD

Drugs & Therapeutics for Acute Cystitis

Drugs for Acute Cystitis (from DrugBank, HMDB, Dgidb, PharmGKB, IUPHAR, NovoSeek, BitterDB):

(show top 50) (show all 527)
# Name Status Phase Clinical Trials Cas Number PubChem Id
1
acetic acid Approved Phase 4 64-19-7 176
2 Apricot Approved Phase 4
3
Bethanechol Approved Phase 4 674-38-4 2370
4
Clarithromycin Approved Phase 4 81103-11-9 84029
5
Dexlansoprazole Approved, Investigational Phase 4 103577-45-3, 138530-94-6 9578005
6
Lansoprazole Approved, Investigational Phase 4 103577-45-3 3883
7
Sulfamethoxazole Approved Phase 4 723-46-6 5329
8
Celecoxib Approved, Investigational Phase 4 169590-42-5 2662
9
Ceftriaxone Approved Phase 4 73384-59-5 5479530 5361919
10
Doripenem Approved, Investigational Phase 4 148016-81-3 73303
11
Ibuprofen Approved Phase 4 15687-27-1 3672
12
Sulbactam Approved Phase 4 68373-14-8
13
Norfloxacin Approved Phase 4 70458-96-7 4539
14
Metronidazole Approved Phase 4 443-48-1 4173
15
Cefazolin Approved Phase 4 25953-19-9 656510 33255
16
Vancomycin Approved Phase 4 1404-90-6 441141 14969
17
Doxycycline Approved, Investigational, Vet_approved Phase 4 564-25-0 54671203
18
Doxazosin Approved Phase 4 74191-85-8 3157
19
Etanercept Approved, Investigational Phase 4 185243-69-0
20
Moxifloxacin Approved, Investigational Phase 4 354812-41-2, 151096-09-2 152946
21
Azithromycin Approved Phase 4 83905-01-5 447043 55185
22
Halofantrine Approved Phase 4 69756-53-2 37393
23
Oxybutynin Approved, Investigational Phase 4 5633-20-5 4634
24
Metformin Approved Phase 4 657-24-9 4091 14219
25
Tinidazole Approved, Investigational Phase 4 19387-91-8 5479
26
Silodosin Approved Phase 4 160970-54-7
27
Sultamicillin Approved, Investigational Phase 4 76497-13-7
28
Aztreonam Approved Phase 4 78110-38-0 5742832 5362041
29
Midazolam Approved, Illicit Phase 4 59467-70-8 4192
30
Acetaminophen Approved Phase 4 103-90-2 1983
31
Naproxen Approved, Vet_approved Phase 4 22204-53-1 1302 156391
32
Ethinyl Estradiol Approved Phase 4 57-63-6 5991
33
Norgestimate Approved, Investigational Phase 4 35189-28-7 6540478
34
Gliclazide Approved Phase 4 21187-98-4 3475
35
4-Aminopyridine Approved Phase 4 504-24-5 1727
36
leucovorin Approved Phase 4 58-05-9 143 6006
37
Trimethoprim Approved, Vet_approved Phase 4 738-70-5 5578
38
Piperacillin Approved Phase 4 66258-76-2 43672
39
Methylene blue Approved, Investigational Phase 4 61-73-4
40
Belladonna Approved, Experimental Phase 4
41
Tranexamic Acid Approved Phase 4 1197-18-8 5526
42
Neomycin Approved, Vet_approved Phase 4 1404-04-2 8378
43
Bacitracin Approved, Vet_approved Phase 4 1405-87-4 439542 10909430
44
Clindamycin Approved, Vet_approved Phase 4 18323-44-9 29029
45
Histamine Approved, Investigational Phase 4 51-45-6 774
46
Ranitidine Approved Phase 4 66357-35-5, 66357-59-3 3001055
47
Acarbose Approved, Investigational Phase 4 56180-94-0 441184
48
Pentoxifylline Approved, Investigational Phase 4 6493-05-6 4740
49
Sargramostim Approved, Investigational Phase 4 83869-56-1, 123774-72-1
50
Acetylcysteine Approved, Investigational Phase 4 616-91-1 12035

Interventional clinical trials:

(show top 50) (show all 968)
# Name Status NCT ID Phase Drugs
1 Low Dose Estriol With Lactobacilli (Gynoflor) Treatment for Preventing Recurrent Urinary Tract Infection in Postmenopausal Women: A Randomized, Open, Parallel-Group Study Unknown status NCT00900653 Phase 4 Gynoflor E (low dose estriol with lactobacillus)
2 The Efficacy of Solifenacin Succinate as Adjuvant Therapy for Symptomatic Non-complicated Urinary Tract Infection in Females Unknown status NCT02094703 Phase 4 Levofloxacin;Solifenacin succinate;Placebo (for Solifenacin succinate)
3 The Impact of Antimicrobial Treatment for Asymptomatic Bacteriuria in Renal Transplant Patients Unknown status NCT02113774 Phase 4
4 An Open Label Non Placebo Study to Evaluate Efficacy and Safety of Levofloxacin as an Empirical Therapy in Patients With Complicated Urinary Tract Infections Unknown status NCT03160807 Phase 4 Levofloxacin;Levofloxacin
5 Randomized Placebo-Controlled Trial of Gentamicin Bladder Instillation for the Prevention of Urinary Tract Infection in Adults at High Risk for Cystitis Due to Intermittent Catheterization Unknown status NCT01884467 Phase 4 Gentamicin;Placebo
6 Randomised Clinical Trial Comparing Fosfomycin vs. Nitrofurantoin for Treatment of Uncomplicated Lower Urinary Tract Infection in Female Adults at Increased Risk of Antibiotic-resistant Bacterial Infection Unknown status NCT01966653 Phase 4 nitrofurantoin;fosfomycin
7 A Open Multi-center Clinical Study on Piperacillin Sodium and Sulbactam Sodium for Injection (2:1) for Treatment of Respiratory and Urinary Tract Infection Unknown status NCT01897831 Phase 4 xin te mie
8 Evaluation of Suprapubic Noble Metal Alloy BIP Foley Catheter in the Prevention of Catheter-associated Urinary Tract Infections in Spinal Cord Injured Patients Unknown status NCT02808000 Phase 4
9 A Randomised, Double-blind, Placebo Controlled Trial Evaluating the Effectiveness of a Cranberry Concentrate (CranrichTM) in Preventing Recurrent Urinary Tract Infections in Adult Women Unknown status NCT02454309 Phase 4
10 Pilot Study to Evaluate the Efficacy of Antiseptic Bladder Lavage Versus Pulsatile Lavage With Physiologic Serum in Catheterized Patients With Asymptomatic Bacteriuria With Uropathogens. Unknown status NCT01772875 Phase 4
11 Comparison of the Effect of Applying Povidone-iodine and Chlorhexidine Solutions for Perinea Washing on Bacteriuria Rate and Type in Patients With Urinary Catheter in Intensive Care Unit Unknown status NCT02032394 Phase 4 Povidone-iodine;Chlorhexidine;Normal saline
12 Recurrent Urinary Tract Infections in Children: Bacterial Identification, Antibiotic Susceptibility Profiling and Cytokine Levels Associated With Antibiotic Prophylaxis Unknown status NCT02357758 Phase 4 Antibiotic Prophylaxis
13 The Use of Toxin Botulinum A Toxin in Patients With Parkinson's Disease and Multiple System Disease, Affected by Refractory Detrusor Overactivity. Unknown status NCT00822913 Phase 4 Intravesical injection of Botulinum A toxin
14 The Effects of Vaginal Estrogen and a Nonhormonal Alternative on the Vaginal and Urinary Microbiome in Women With Genitourinary Syndrome of Menopause: A Randomized Controlled Trial Unknown status NCT02869165 Phase 4 Premarin vaginal cream;Apricot kernel oil
15 Effectiveness of Bethanechol Chloride and Early Bladder Training for Prevention of Bladder Dysfunction After Radical Hysterectomy in Cervical Cancer Stage IB - IIA Unknown status NCT02910596 Phase 4 bethanechol chloride
16 Clinical Impact of Bacteriuria on Chronic Inflammation in Asymptomatic Hemodialysis Patients Unknown status NCT01570556 Phase 4
17 Functional Electrical Stimulation-Assisted Walking: Reduction of Secondary Complications Due to Spinal Cord Injury Unknown status NCT00201968 Phase 4
18 A Prospective Study Comparing the Success Rate of Injection of Dextranomer /Hyaluronic Acid (DefluxR) Versus Polyacrylate Polyalcohol (VantrisR) for Treatment of Bilateral Similar Grade Vesicoureteral Reflux in Children Unknown status NCT02271035 Phase 4 Deflux;Vantris
19 Effect of Vaginal Estrogen on Asymptomatic Microhematuria (AMH): A Randomized Controlled Trial [EVER Study] Unknown status NCT02213757 Phase 4 Premarin vaginal estrogen cream;Placebo vaginal cream
20 Comparison of the Efficacy of Triple Therapy With or Without Acetylcysteine in the First Line of Helicobacter Pylori Infection- A Multicenter Randomized Comparative Trial Unknown status NCT02249546 Phase 4 N-acetylcysteine + PPI-amoxicillin-clarithromycin;PPI-amoxicillin-clarithromycin
21 Effect of Anti-diabetic Drugs on Glycemic Variability. A Comparison Between Gliclazide MR (Modified Release) and Dapagliflozin on Glycemic Variability Measured by Continuous Glucose Monitoring (CGM) in Patients With Uncontrolled Type 2 Diabetes Unknown status NCT02925559 Phase 4 Dapagliflozin;Gliclazide MR
22 Vaginal Estrogen for the Prevention of Recurrent Urinary Tract Infection in Postmenopausal Women Completed NCT01958073 Phase 4 Conjugated Estrogen Vaginal Cream;Estradiol Ring;Placebo
23 Use of Standardized Delegation Form in Diagnosing and Treating Acute Cystitis in Primary Care Facilities. Completed NCT01132131 Phase 4
24 Clinical and Microbiologic Efficacy of Ciprofloxacin for the Treatment of Uncomplicated Urinary Tract Infection in Adult Women. Completed NCT03366207 Phase 4 Ciprofloxacin
25 Prospective, Open Label Non-comparative, Multi-center Trial to Evaluate the Efficacy and Safety of Cipro® XR 500 mg Once Daily for 3 Days in Treating Female Patients With Acute, Uncomplicated, Symptomatic Lower Urinary Tract Infections Completed NCT00669994 Phase 4 Ciprofloxacin
26 Open Label Study on the Bacteriological and Clinical Efficacy and Safety of a Nitrofurantoin Formulation Given Twice Daily (Bid) for Seven Days in Uncomplicated Urinary Tract Infection in Adults Completed NCT01092351 Phase 4 Nitrofurantoin
27 Cipro® XR Excellence in Therapeutic Response and Activity (eXtRa) - Assessing Symptom Relief in Urinary Tract Infections Completed NCT00676533 Phase 4 Cipro XR (Ciprofloxacin, BAYQ3939)
28 Pharmacokinetics of Ciprofloxacin in Pediatric Patients With Emphasis on Renal Excretion Completed NCT02598362 Phase 4 ciprofloxacin
29 Use of Antibiotic Prophylaxis on Urethral Catheter Withdrawal: A Randomized Double-Blind Placebo-Controlled Trial Completed NCT00126698 Phase 4 trimethoprim-sulfamethoxazole;ciprofloxacin
30 Prospective, Open-Label, Noncomparative, Multicenter Study to Evaluate the Efficacy and Safety of Ciprofloxacin Extended Release (Cipro XR) 1000 mg Tablets Given Once Daily for 7 to 14 Days in the Treatment of Patients 18 Years or Older With Complicated Urinary Tract Infections Caused by Pseudomonas Aeruginosa and Other Common Uropathogens Completed NCT00481689 Phase 4 Cipro XR (Ciprofloxacin, BAYQ3939)
31 Immediate vs. Conditional Use of Antibiotics in Uncomplicated Urinary Tract Infection (UTI) - a Comparative Effectiveness Study in General Practice (ICUTI) Completed NCT01488955 Phase 4 Ibuprofen;Fosfomycin-Trometamol
32 Does Prophylaxis With Macrobid Reduce the Incidence of Urinary Tract Infection in Patients Who Receive a Sub-Urethral Sling for the Treatment of Stress Urinary Incontinence: Randomized, Double Blinded Placebo Controlled Clinical Trial Completed NCT00734968 Phase 4 Nitrofurantoin
33 A Randomized, Multicenter, Parallel Group Study to Evaluate Safety and Efficacy of a Weekly Oral Cyclic Antibiotic Programme in the Prevention of Urinary Tract Infection on Neurological Bladder Completed NCT01388413 Phase 4 Weekly Oral Cyclic Antibiotic programme
34 Relevance of Biomarkers and Clinical Predictors of Outcome in Unselected Population With Febrile Urinary Tract Infection at Primary Care and Emergency Department in a Prospective, Randomized Cohort Trial Comparing Short (7 Days) Antibiotic Treatment With Conventional Treatment (14 Days) Completed NCT00809913 Phase 4 short treatment (ciprofloxacin)
35 The Bacteriuria in Renal Transplantation (BiRT) Study: A Prospective, Randomized, Parallel-group, Multicenter, Open-label, Superiority Trial Comparing Antibiotics Versus no Treatment in the Prevention of Symptomatic Urinary Tract Infection in Kidney Transplant Recipients With Asymptomatic Bacteriuria Completed NCT01871753 Phase 4
36 Nitrofurantoin Administration for the Prevention of Short-Term Catheter Associated Urinary Tract Infection After Pelvic Surgery (NAUTICA): A Randomized Controlled Trial Completed NCT03287089 Phase 4 Nitrofurantoin 100 MG;Placebo Oral Tablet
37 A Prospective Study on the Usage Patterns of Doripenem in the Asia Pacific Region Completed NCT00986102 Phase 4 doripenem
38 Antibiotic Prophylaxis for Urinary Tract Infection in Patients Requiring Catheterization After Urogynecologic Surgery Completed NCT01450800 Phase 4 Nitrofurantoin;Placebo
39 EXPRESS: Evaluating Cipro XR Patient Response, Education, Safety, and Satisfaction Completed NCT00663806 Phase 4
40 Randomized Controled Multicentric Trial, of Non Inferiority, Comparing Two Durations of Antibiotherapy (5 Days Versus 10 Days) in COMMUNAUTARY Acute Uncomplicated Pyelonephritis. Completed NCT00873626 Phase 4 levofloxacin, ciprofloxacin and ofloxacin (fluoroquinolones)
41 Fosfomycin-Trometamol in Urinary Tract Infection Prophylaxis After Kidney Transplantation. Randomized Controlled Trial. Completed NCT01820897 Phase 4 Fosfomycin-Trometamol;Sulfamethoxazole trimethoprim
42 Antibiotic Treatment for Intermittent Bladder Catheterisation: A Randomised Controlled Trial of Once Daily Prophylaxis Completed NCT02145338 Phase 4 Nitrofurantoin or Trimethoprim or Cefalexin
43 A Randomized, Double-blind, Placebo-controlled Trial of Nitrofurantoin Prophylaxis During Catheterization for Acute Postoperative Urinary Retention After Pelvic Reconstructive Surgery Completed NCT02727322 Phase 4 Nitrofurantoin;Placebo
44 Perioperative Disodium Fosfomycin in the Prophylaxis of Urinary Tract Infection in Kidney Transplant Recipients. Controlled Clinical Trial (PERIFOS Trial) Completed NCT03235947 Phase 4 Fosfomycin disodium;Trimethoprim / Sulfamethoxazole;Intravenous placebo
45 The EDGE Consortium: A Randomized Trial of Preoperative Prophylactic Antibiotics Prior to Percutaneous Nephrolithotomy: Part 1 Completed NCT02384200 Phase 4 nitrofurantoin monohydrate/macrocrystalline capsules;ampicillin;gentamicin;vancomycin;ceftriaxone
46 A Post Marketing Surveillance Study on the Safety and Effectiveness of Doripenem in the Therapy of Thai Patients With Nosocomial Pneumonia, Complicated Intra-Abdominal Infections and Complicated Urinary Tract Infections Completed NCT00965848 Phase 4 Doripenem
47 A Prospective, Randomized, Parallel-group, Multi-center Study to Compare the Occurrence of Urinary Tract Infections in Patients With Spinal Cord Injury Using Either Coated or Uncoated Intermittent Catheters. Completed NCT00318591 Phase 4
48 Antimuscarinics as the First-line Treatment for Male With International Prostate Symptom Score (IPSS) Voiding-to-storage Subscore Rati (IPSS-V/S)≤1-- A Prospective Randomized Study Comparing With α-blockers Completed NCT01661621 Phase 4 Detrusitol 4 mg QD;Doxazosin 4 mg QD
49 Double-blind, Randomized, Placebo-controlled Study of Enbrel (Etanercept) in the Treatment of Rheumatoid Arthritis Subjects With Comorbid Disorders Completed NCT00132418 Phase 4 Enbrel;Placebo
50 Randomized Controlled Clinical Trial of Efficacy of Fosfomycin Versus Ciprofloxacin as Antibiotic Prophylaxis Prior to Ultrasound Guided Transrectal Prostate Biopsy Completed NCT01803191 Phase 4 Fosfomycin 3 g;Ciprofloxacin 500 mg

Search NIH Clinical Center for Acute Cystitis

Inferred drug relations via UMLS 72 / NDF-RT 51 :


acetohydroxamic acid
Acetohydroxamic acid
acetyl sulfisoxazole
Amoxicillin
Ampicillin
Aztreonam
Cefadroxil
Cefprozil
Ceftazidime
Cefuroxime
Cinoxacin
Ciprofloxacin
Clavulanic acid
Demeclocycline
Doxycycline
Enoxacin
Flavoxate
gemifloxacin mesylate
GENTAMICIN SULFATE PWDR
lomefloxacin
Methenamine
Methylene blue
Minocycline
Nitrofurantoin
Nitrofurantoin
NITROFURANTOIN, MACROCRYSTALS
Polymyxin B
Streptomycin
Sulfadiazine
Sulfamethizole
Sulfisoxazole
Sulfisoxazole Diolamine
Tetracycline
Trimethoprim
TRIMETHOPRIM SULFATE

Genetic Tests for Acute Cystitis

Anatomical Context for Acute Cystitis

MalaCards organs/tissues related to Acute Cystitis:

41
Kidney, Prostate, Spinal Cord, Testes, Colon, Liver, Neutrophil

Publications for Acute Cystitis

Articles related to Acute Cystitis:

(show top 50) (show all 21915)
# Title Authors PMID Year
1
Determination of antibiotic resistance genes and virulence factors in Escherichia coli isolated from Turkish patients with urinary tract infection. 38 17
31271618 2019
2
Non-alcoholic Fatty Liver Disease is Associated with Recurrent Urinary Tract Infection in Premenopausal Women Independent of Metabolic Syndrome. 38 17
31280506 2019
3
Urinary Tract Infection in Elderly: Clinical Profile and Outcome. 38 17
31331128 2018
4
Knot positioning during McDonald cervical cerclage, does it make a difference? A cohort study. 38
29764255 2019
5
Pregnancy outcomes of adolescent primigravida and risk of pregnancy-induced hypertension: a hospital-based study in Southern Thailand. 38
31180254 2019
6
Urine dipstick low sensitivity for UTI diagnosis in febrile infants *. 38
31418615 2019
7
Prognosis of urinary tract infection caused by KPC-producing Klebsiella pneumoniae: The impact of inappropriate empirical treatment. 38
31276705 2019
8
Therapeutic effect of Dongbai-Tonglin-Fang, a Chinese herbal formula, on urinary tract infection in rat model. 38
31195030 2019
9
Giant bladder stone with history of recurrence urinary tract infections: A rare case. 38
31275809 2019
10
Emphysematous pyelitis in a solitary functioning kidney. 38
31211095 2019
11
Maternal urinary tract infection during pregnancy and long-term infectious morbidity of the offspring. 38
31319353 2019
12
Performance of the cobas u 701 Analyzer in Urinary Tract Infection Screening. 38
31037865 2019
13
Validity of microscopy for diagnosing urinary tract infection in general practice - a systematic review. 38
31304845 2019
14
Drug Resistance and Integron Genes in Escherichia coli Isolated from Urinary Tract Infection. 38
30961771 2019
15
Clinical characteristics and treatment outcomes of Enterococcus durans bacteremia: a 20-year experience in a tertiary care hospital. 38
31243595 2019
16
Safety and efficacy of opicinumab in patients with relapsing multiple sclerosis (SYNERGY): a randomised, placebo-controlled, phase 2 trial. 38
31285147 2019
17
Safety and Efficacy of Ceftazidime-Avibactam in the Treatment of Children ≥3 Months to <18 Years With Complicated Urinary Tract Infection: Results from a Phase 2 Randomized, Controlled Trial. 38
31335570 2019
18
Primary vesicoureteral reflux; what have we learnt from the recently published randomized, controlled trials? 38
30132079 2019
19
Role of Late DMSA Renal Scan in Detecting High-Grade Vesicoureteral Reflux. 38
30859438 2019
20
A Comparison of 30-Day Hospital Readmission and Complication Rates After Outpatient Versus Inpatient 1 and 2 Level Anterior Cervical Discectomy and Fusion Surgery: An Analysis of a Medicare Patient Sample. 38
31128307 2019
21
Prevalence of urolithiasis among the Uyghur children of China: a population-based cross-sectional study. 38
30993821 2019
22
What US hospitals are currently doing to prevent common device-associated infections: results from a national survey. 38
31015378 2019
23
Efficacy of ertugliflozin in monotherapy or combination therapy in patients with type 2 diabetes: A pooled analysis of placebo-controlled studies. 38
31081371 2019
24
Phenotypic screening for quinolone resistance in Escherichia coli. 38
31214796 2019
25
Mixed-methods approach to exploring patients' perspectives on the acceptability of a urinary biomarker test in replacing cystoscopy for bladder cancer surveillance. 38
30694612 2019
26
Prevention of Infectious Complications in Acute Pancreatitis: Results of a Single-Center, Randomized, Controlled Trial. 38
31404018 2019
27
Girthiness: Retrospective Study of 37 Horses (2004-2016). 38
31405487 2019
28
Antagonistic activity of recombinant Lactococcus lactis NZ1330 on the adhesion properties of Escherichia coli causing urinary tract infection. 38
31112774 2019
29
Prevalence and risk factors for fosfomycin resistance among Escherichia coli strains isolated from males with community febrile urinary tract infection. 38
30075982 2019
30
Re: Host Restriction of Escherichia coli Recurrent Urinary Tract Infection Occurs in a Bacterial Strain-Specific Manner. 38
31063066 2019
31
Gentamicin-Assisted Mycogenic Selenium Nanoparticles Synthesized Under Gamma Irradiation for Robust Reluctance of Resistant Urinary Tract Infection-Causing Pathogens. 38
31396853 2019
32
Whole-Genome Sequences of Two Multidrug-Resistant Acinetobacter baumannii Strains Isolated from Patients with Urinary Tract Infection in Ghana. 38
31371532 2019
33
Uva-ursi extract and ibuprofen as alternative treatments for uncomplicated urinary tract infection in women (ATAFUTI): a factorial randomized trial. 38
30685500 2019
34
Patient survival after kidney transplantation: important role of graft-sustaining factors as determined by predictive modeling using random survival forest analysis. 38
31403555 2019
35
Is it possible to extrapolate the rates of resistance of Escherichia coli from asymptomatic bacteriuria in pregnant women to those of E. coli in uncomplicated community-acquired UTI? 38
31328907 2019
36
Recurrent Uncomplicated Urinary Tract Infections in Women: AUA/CUA/SUFU Guideline. 38
31042112 2019
37
Ibuprofen lacks direct antimicrobial properties for the treatment of urinary tract infection isolates. 38
31184571 2019
38
Serum soluble ST2 as a marker of renal scar in pediatric upper urinary tract infection. 38
31153005 2019
39
Rapid diagnostic testing in the management of urinary tract infection: Potentials and limitations. 38
30928179 2019
40
Antibacterial immunomodulatory and antibiofilm triple effect of Salivaricin LHM against Pseudomonas aeruginosa urinary tract infection model. 38
31136751 2019
41
Risk Factors for Urinary Tract Infection After Kidney Transplant: A Retrospective Analysis. 38
31424358 2019
42
Population dynamics of an Escherichia coli ST131 lineage during recurrent urinary tract infection. 38
31409795 2019
43
Genotypic identification of Pseudomonas aeruginosa strains isolated from patients with urinary tract infection. 38
31300119 2019
44
Early urinary tract infection after spinal cord injury: a retrospective inpatient cohort study. 38
31388122 2019
45
Bacterial Microcompartment-Mediated Ethanolamine Metabolism in Escherichia coli Urinary Tract Infection. 38
31138611 2019
46
Re: Impact of Foley Catheter Placement by Medical Students on Rates of Postoperative Urinary Tract Infection. 38
31021296 2019
47
Gender Differences for Hip and Knee Arthroplasty: Complications and Healthcare Utilization. 38
31003781 2019
48
IgA-producing lymphoplasmacytic lymphoma carrying the chromosomal abnormality t(8;14). 38
31391404 2019
49
Correction to: Common findings of blaCTX-M-55-encoding 104-139 kbp plasmids harbored by extended-spectrum β-lactamase-producing Escherichia coli in pork meat, wholesale market workers, and patients with urinary tract infection in Vietnam. 38
29279979 2019
50
Carbapenem-Resistant KPC- and TEM-Producing Escherichia coli ST131 Isolated from a Hospitalized Patient with Urinary Tract Infection: First Isolation in Molise Region, Central Italy, July 2018. 38
31386590 2019

Variations for Acute Cystitis

Expression for Acute Cystitis

Search GEO for disease gene expression data for Acute Cystitis.

Pathways for Acute Cystitis

Pathways related to Acute Cystitis according to GeneCards Suite gene sharing:

(show all 24)
# Super pathways Score Top Affiliating Genes
1
Show member pathways
12.99 TLR4 MCU IL6 IL18 CXCL8 CXCL1
2
Show member pathways
12.23 LCN2 IL6 CXCL8 CXCL1 CCL2
3
Show member pathways
12.21 IL6 CRP CCL2 ALB
4 11.88 TLR4 IL6 CXCL8 CXCL1 CCL2
5 11.85 TLR4 IL6 CXCL8 CXCL1
6 11.84 IL6 CXCL1 CCL2
7 11.82 LCN2 IL6 IL18 CXCL8 CCL2
8 11.81 IL6 CXCL8 CXCL1
9
Show member pathways
11.79 TLR4 IL6 CXCL8 CXCL1
10 11.78 IL6 CXCL8 CCL2
11 11.74 TLR4 IL18 CXCL8
12 11.64 TLR4 IL6 CXCL8
13 11.63 TLR4 IL6 IL18 CXCL8 CXCL1
14 11.59 IL6 IL18 CXCL1 CCL2
15 11.54 IL6 CXCL8 CCL2
16 11.42 TLR4 IL18 CCL2
17 11.4 TLR4 IL6 IL18 CXCL8 CXCL1
18 11.26 IL6 CXCL8 CCL2
19 11.24 TLR4 IL6 IL18 CXCL8 CCL2
20 11.09 IL6 IL18 CXCL8 CXCL1 CCL2
21 11.07 TLR4 IL6 IL18 CXCL8 CXCL1 CCL2
22 11.04 IL6 IL18 CXCL8 CXCL1 CCL2
23 10.93 IL6 CXCL8 CRP
24 10.9 IL6 IL18 CXCL8 CXCL1 CCL2

GO Terms for Acute Cystitis

Cellular components related to Acute Cystitis according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 extracellular space GO:0005615 9.56 LCN2 IL6 IL18 CXCL8 CXCL1 CRP
2 extracellular region GO:0005576 9.28 UMOD LCN2 IL6 IL18 CXCL8 CXCL1

Biological processes related to Acute Cystitis according to GeneCards Suite gene sharing:

(show all 16)
# Name GO ID Score Top Affiliating Genes
1 positive regulation of gene expression GO:0010628 9.8 TLR4 LCN2 IL6 IL18 CRP
2 immune response GO:0006955 9.73 TLR4 IL6 IL18 CXCL8 CXCL1 CCL2
3 neutrophil chemotaxis GO:0030593 9.7 CXCL8 CXCL1 CCL2
4 cellular response to interleukin-1 GO:0071347 9.69 LCN2 CXCL8 CCL2
5 chemokine-mediated signaling pathway GO:0070098 9.63 CXCL8 CXCL1 CCL2
6 cytokine-mediated signaling pathway GO:0019221 9.63 LCN2 IL6 IL18 CXCL8 CXCL1 CCL2
7 positive regulation of nitric-oxide synthase biosynthetic process GO:0051770 9.56 TLR4 CCL2
8 PERK-mediated unfolded protein response GO:0036499 9.55 CXCL8 CCL2
9 lipopolysaccharide-mediated signaling pathway GO:0031663 9.5 TLR4 IL18 CCL2
10 inflammatory response GO:0006954 9.5 TLR4 IL6 IL18 CXCL8 CXCL1 CRP
11 neutrophil activation GO:0042119 9.49 IL18 CXCL8
12 T-helper 1 type immune response GO:0042088 9.48 TLR4 IL18
13 negative regulation of lipid storage GO:0010888 9.43 IL6 CRP
14 positive regulation of neuroinflammatory response GO:0150078 9.37 IL6 IL18
15 interferon-gamma production GO:0032609 9.24 TLR4
16 cellular response to lipopolysaccharide GO:0071222 9.1 TLR4 LCN2 IL6 CXCL8 CXCL1 CCL2

Molecular functions related to Acute Cystitis according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 chemokine activity GO:0008009 9.33 CXCL8 CXCL1 CCL2
2 cytokine activity GO:0005125 9.02 IL6 IL18 CXCL8 CXCL1 CCL2
3 glucose:sodium symporter activity GO:0005412 8.96 SLC5A4 SLC5A2

Sources for Acute Cystitis

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
17 EFO
18 ExPASy
19 FMA
28 GO
29 GTR
30 HGMD
31 HMDB
32 HPO
33 ICD10
34 ICD10 via Orphanet
35 ICD9CM
36 IUPHAR
37 KEGG
38 LifeMap
40 LOVD
42 MedGen
44 MeSH
45 MESH via Orphanet
46 MGI
49 NCI
50 NCIt
51 NDF-RT
54 NINDS
55 Novoseek
57 OMIM
58 OMIM via Orphanet
62 PubMed
64 QIAGEN
69 SNOMED-CT via HPO
70 TGDB
71 Tocris
72 UMLS
73 UMLS via Orphanet
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