Aliases & Classifications for Acute Cystitis

MalaCards integrated aliases for Acute Cystitis:

Name: Acute Cystitis 12 15 71 32
Urinary Tract Infection 12 17 71
Urinary Tract Infections 42 15
Recurrent Urinary Tract Infection 71

Classifications:



External Ids:

Disease Ontology 12 DOID:13148
ICD9CM 34 595.0
NCIt 49 C26934
SNOMED-CT 67 68226007
ICD10 32 N30.0 N39.0
UMLS 71 C0042029 C0149523 C0262655

Summaries for Acute Cystitis

MedlinePlus : 42 The urinary system is the body's drainage system for removing wastes and extra water. It includes two kidneys, two ureters, a bladder, and a urethra. Urinary tract infections (UTIs) are the second most common type of infection in the body. You may have a UTI if you notice Pain or burning when you urinate Fever, tiredness, or shakiness An urge to urinate often Pressure in your lower belly Urine that smells bad or looks cloudy or reddish Pain in your back or side below the ribs People of any age or sex can get UTIs. But about four times as many women get UTIs as men. You're also at higher risk if you have diabetes, need a tube to drain your bladder, or have a spinal cord injury. If you think you have a UTI it is important to see your doctor. Your doctor can tell if you have a UTI with a urine test. Treatment is with antibiotics. NIH: National Institute of Diabetes and Digestive and Kidney Diseases

MalaCards based summary : Acute Cystitis, also known as urinary tract infection, is related to autosomal dominant polycystic kidney disease and cystitis, and has symptoms including fever, pruritus and uti symptoms. An important gene associated with Acute Cystitis is IL6 (Interleukin 6), and among its related pathways/superpathways are Innate Immune System and Measles. The drugs Tranexamic Acid and Apricot have been mentioned in the context of this disorder. Affiliated tissues include kidney, prostate and spinal cord, and related phenotypes are adipose tissue and cardiovascular system

Disease Ontology : 12 A cystitis characterized by a sudden onset or severe symptoms.

Wikipedia : 74 A urinary tract infection (UTI) is an infection that affects part of the urinary tract. When it affects... more...

Related Diseases for Acute Cystitis

Diseases in the Cystitis family:

Acute Cystitis Chronic Cystitis

Diseases related to Acute Cystitis via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50) (show all 932)
# Related Disease Score Top Affiliating Genes
1 autosomal dominant polycystic kidney disease 33.1 LCN2 INS CCL2 ALB
2 cystitis 33.1 VIM UPK1A UMOD TLR4 IL6 IL18
3 ureteral disease 32.7 LCN2 IL6 CCL2 ALB
4 hydronephrosis 32.1 KLK3 IL6 CRP CCL2 ALB
5 urolithiasis 32.0 UMOD IL6 ALB
6 urinary tract obstruction 31.9 UMOD LCN2 KLK3 CRP CCL2 ALB
7 chronic pyelonephritis 31.8 UMOD TLR4 SERPINA3 CRP ALB
8 urethritis 31.8 TLR4 KLK3 IL6 CRP
9 constipation 31.7 VIM INS IL6 CRP ALB
10 end stage renal disease 31.7 UMOD INS IL6 CRP ALB
11 interstitial cystitis 31.6 UPK1A UMOD IL6
12 chlamydia 31.6 TLR4 IL6 IL18 CRP CCL2
13 nephrolithiasis 31.5 UMOD LCN2 INS ALB
14 bronchitis 31.5 TLR4 IL6 CRP ALB
15 endocarditis 31.4 IL6 CRP ALB
16 osteomyelitis 31.4 TLR4 IL6 CCL2
17 pre-eclampsia 31.3 TLR4 INS IL6 IL18 CRP ALB
18 interstitial nephritis 31.3 UMOD CRP ALB
19 acute kidney failure 31.3 UMOD LCN2 IL18 ALB
20 peritonitis 31.3 TLR4 IL6 IL18 CRP CCL2 ALB
21 autoimmune disease 31.3 INS IL6 IL18 CRP CCL2
22 septic arthritis 31.3 TLR4 IL6 CRP
23 xanthogranulomatous pyelonephritis 31.3 SERPINA3 CCL2
24 salmonellosis 31.3 TLR4 IL6 IL18 ALB
25 kidney disease 31.3 UMOD SERPINA3 LCN2 INS IL6 IL18
26 endophthalmitis 31.2 IL6 CRP ALB
27 pharyngitis 31.2 IL6 CRP ALB
28 acute pyelonephritis 31.2 LCN2 IL6 CRP ALB
29 otitis media 31.2 TLR4 IL6 CRP CCL2 ALB
30 bronchiolitis 31.2 TLR4 IL6 CRP CCL2
31 decubitus ulcer 31.2 INS IL6 CRP ALB
32 proteasome-associated autoinflammatory syndrome 1 31.2 TLR4 IL6 IL18 CRP CCL2
33 pyelonephritis 31.2 UMOD TLR4 LCN2 IL6 CRP CCL2
34 cerebrovascular disease 31.1 TLR4 SERPINA3 INS IL6 CRP
35 bacteriuria 31.1 UMOD TLR4 PAPOLG IL6 IL18 CXCL1
36 kawasaki disease 31.1 IL6 IL18 CRP CCL2 ALB
37 anuria 31.1 LCN2 CRP ALB
38 drug allergy 31.1 INS CRP ALB
39 uremia 31.1 INS IL6 CRP ALB
40 pyuria 31.1 LCN2 KLK3 IL6 CRP ALB
41 multiple sclerosis 31.1 TLR4 IL6 IL18 CXCL1 CCL2 ALB
42 diabetes mellitus 31.1 UMOD TLR4 SLC5A2 LCN2 INS IL6
43 congestive heart failure 31.1 INS IL6 CRP ALB
44 acute kidney tubular necrosis 31.1 UMOD LCN2 IL6 IL18 ALB
45 diverticulitis 31.1 IL6 CRP ALB
46 crohn's disease 31.1 TLR4 IL6 IL18 CRP CCL2 ALB
47 placenta disease 31.1 TLR4 SERPINA3 INS IL6 CRP
48 chronic kidney disease 31.0 UMOD TLR4 SLC5A2 SERPINA3 LCN2 INS
49 endometritis 31.0 TLR4 IL6 CXCL1
50 hemorrhagic cystitis 31.0 TLR4 EPRS1 ALB

Comorbidity relations with Acute Cystitis via Phenotypic Disease Network (PDN): (show top 50) (show all 421)


3-Hydroxyacyl-Coa Dehydrogenase Deficiency Acquired Thrombocytopenia
Active Peptic Ulcer Disease Acute Anterolateral Myocardial Infarction
Acute Conjunctivitis Acute Cor Pulmonale
Acute Kidney Failure Acute Maxillary Sinusitis
Acute Myocardial Infarction Acute Pancreatitis
Acute Sphenoidal Sinusitis Acute Vascular Insufficiency of Intestine
Adjustment Disorder Adrenal Gland Disease
Agammaglobulinemia, X-Linked Age-Related Hearing Loss
Alcoholic Hepatitis Alcoholic Liver Cirrhosis
Alcoholic Neuropathy Algoneurodystrophy
Allergic Urticaria Alopecia, Neurologic Defects, and Endocrinopathy Syndrome
Alzheimer Disease Amnestic Disorder
Amyloidosis Anemia, Autoimmune Hemolytic
Anorexia Nervosa Anus Cancer
Anxiety Aortic Aneurysm
Aortic Atherosclerosis Aortic Valve Disease 1
Asthma Atrioventricular Block
Atrophic Gastritis Atypical Depressive Disorder
Autonomic Nervous System Disease Bacteremia 2
Bacterial Meningitis Balanoposthitis
Basilar Artery Insufficiency Benign Essential Hypertension
Benign Hypertensive Renal Disease Biliary Tract Disease
Bipolar Disorder Bladder Cancer
Bladder Disease Bladder Neck Obstruction
Bleeding Disorder, Platelet-Type, 11 Blepharitis

Graphical network of the top 20 diseases related to Acute Cystitis:



Diseases related to Acute Cystitis

Symptoms & Phenotypes for Acute Cystitis

UMLS symptoms related to Acute Cystitis:


fever, pruritus, uti symptoms

MGI Mouse Phenotypes related to Acute Cystitis:

45
# Description MGI Source Accession Score Top Affiliating Genes
1 adipose tissue MP:0005375 9.86 EPRS1 IL18 IL6 INS LCN2 SLC5A2
2 cardiovascular system MP:0005385 9.85 ALB CRP IL18 IL6 INS KLK3
3 homeostasis/metabolism MP:0005376 9.77 ALB CD248 CRP EPRS1 IL18 IL6
4 immune system MP:0005387 9.4 ALB CCL2 CD248 CRP IL18 IL6

Drugs & Therapeutics for Acute Cystitis

Drugs for Acute Cystitis (from DrugBank, HMDB, Dgidb, PharmGKB, IUPHAR, NovoSeek, BitterDB):

(show top 50) (show all 532)
# Name Status Phase Clinical Trials Cas Number PubChem Id
1
Tranexamic Acid Approved Phase 4 1197-18-8 5526
2 Apricot Approved Phase 4
3
Bethanechol Approved Phase 4 674-38-4 2370
4
Clarithromycin Approved Phase 4 81103-11-9 84029
5
Acetylcysteine Approved, Investigational Phase 4 616-91-1 12035
6
Pentoxifylline Approved, Investigational Phase 4 6493-05-6 4740
7
Sargramostim Approved, Investigational Phase 4 83869-56-1, 123774-72-1
8
Lansoprazole Approved, Investigational Phase 4 103577-45-3 3883
9
Dexlansoprazole Approved, Investigational Phase 4 103577-45-3, 138530-94-6 9578005
10
Sulfamethoxazole Approved Phase 4 723-46-6 5329
11
Celecoxib Approved, Investigational Phase 4 169590-42-5 2662
12
Ceftriaxone Approved Phase 4 73384-59-5 5361919 5479530
13
Doripenem Approved, Investigational Phase 4 148016-81-3 73303
14
Ibuprofen Approved Phase 4 15687-27-1 3672
15
Sulbactam Approved Phase 4 68373-14-8
16
Norfloxacin Approved Phase 4 70458-96-7 4539
17
Metronidazole Approved Phase 4 443-48-1 4173
18
Ampicillin Approved, Vet_approved Phase 4 69-53-4 6249
19
Cefazolin Approved Phase 4 25953-19-9 656510 33255
20
Chlorhexidine Approved, Vet_approved Phase 4 55-56-1 9552079 2713
21
Vancomycin Approved Phase 4 1404-90-6 14969 441141
22
Doxycycline Approved, Investigational, Vet_approved Phase 4 564-25-0 54671203
23
Doxazosin Approved Phase 4 74191-85-8 3157
24
Etanercept Approved, Investigational Phase 4 185243-69-0
25
Halofantrine Approved Phase 4 69756-53-2 37393
26
Lactitol Approved, Investigational Phase 4 585-88-6, 585-86-4 493591
27
Moxifloxacin Approved, Investigational Phase 4 354812-41-2, 151096-09-2 152946
28
Oxybutynin Approved, Investigational Phase 4 5633-20-5 4634
29
Tinidazole Approved, Investigational Phase 4 19387-91-8 5479
30
Silodosin Approved Phase 4 160970-54-7
31
Sultamicillin Approved, Investigational Phase 4 76497-13-7
32
Aztreonam Approved Phase 4 78110-38-0 5742832 5362041
33
Midazolam Approved, Illicit Phase 4 59467-70-8 4192
34
Acetaminophen Approved Phase 4 103-90-2 1983
35
Naproxen Approved, Vet_approved Phase 4 22204-53-1 1302 156391
36
Gliclazide Approved Phase 4 21187-98-4 3475
37
4-Aminopyridine Approved Phase 4 504-24-5 1727
38
leucovorin Approved Phase 4 58-05-9 6006 143
39
Trimethoprim Approved, Vet_approved Phase 4 738-70-5 5578
40
Piperacillin Approved Phase 4 66258-76-2 43672
41
Zinc Approved, Investigational Phase 4 7440-66-6 32051
42
Methylene blue Approved, Investigational Phase 4 61-73-4
43
Belladonna Approved, Experimental Phase 4
44
Neomycin Approved, Vet_approved Phase 4 1404-04-2 8378
45
Bacitracin Approved, Vet_approved Phase 4 1405-87-4 439542 10909430
46
Metformin Approved Phase 4 657-24-9 14219 4091
47
Histamine Approved, Investigational Phase 4 51-45-6 774
48
Famotidine Approved Phase 4 76824-35-6 3325
49
Mannitol Approved, Investigational Phase 4 69-65-8 6251 453
50
Ertapenem Approved, Investigational Phase 4 153832-46-3 150610

Interventional clinical trials:

(show top 50) (show all 1072)
# Name Status NCT ID Phase Drugs
1 Low Dose Estriol With Lactobacilli (Gynoflor) Treatment for Preventing Recurrent Urinary Tract Infection in Postmenopausal Women: A Randomized, Open, Parallel-Group Study Unknown status NCT00900653 Phase 4 Gynoflor E (low dose estriol with lactobacillus)
2 The Efficacy of Solifenacin Succinate as Adjuvant Therapy for Symptomatic Non-complicated Urinary Tract Infection in Females Unknown status NCT02094703 Phase 4 Levofloxacin;Solifenacin succinate;Placebo (for Solifenacin succinate)
3 The Impact of Antimicrobial Treatment for Asymptomatic Bacteriuria in Renal Transplant Patients Unknown status NCT02113774 Phase 4
4 Efficacy of Temocillin in Urinary Tract Infection Due to ESBL Producing and AmpC Hyperproducing Enterobacteriaceae Unknown status NCT02681263 Phase 4 Temocillin
5 An Open Label Non Placebo Study to Evaluate Efficacy and Safety of Levofloxacin as an Empirical Therapy in Patients With Complicated Urinary Tract Infections Unknown status NCT03160807 Phase 4 Levofloxacin;Levofloxacin
6 Noroxin Efficacy and Safety Trial Unknown status NCT03506256 Phase 4 Norfloxacin 400 MG
7 Randomized Placebo-Controlled Trial of Gentamicin Bladder Instillation for the Prevention of Urinary Tract Infection in Adults at High Risk for Cystitis Due to Intermittent Catheterization Unknown status NCT01884467 Phase 4 Gentamicin;Placebo
8 Randomised Clinical Trial Comparing Fosfomycin vs. Nitrofurantoin for Treatment of Uncomplicated Lower Urinary Tract Infection in Female Adults at Increased Risk of Antibiotic-resistant Bacterial Infection Unknown status NCT01966653 Phase 4 nitrofurantoin;fosfomycin
9 A Open Multi-center Clinical Study on Piperacillin Sodium and Sulbactam Sodium for Injection (2:1) for Treatment of Respiratory and Urinary Tract Infection Unknown status NCT01897831 Phase 4 xin te mie
10 Evaluation of Suprapubic Noble Metal Alloy BIP Foley Catheter in the Prevention of Catheter-associated Urinary Tract Infections in Spinal Cord Injured Patients Unknown status NCT02808000 Phase 4
11 A Randomised, Double-blind, Placebo Controlled Trial Evaluating the Effectiveness of a Cranberry Concentrate (CranrichTM) in Preventing Recurrent Urinary Tract Infections in Adult Women Unknown status NCT02454309 Phase 4
12 Comparison of the Effect of Applying Povidone-iodine and Chlorhexidine Solutions for Perinea Washing on Bacteriuria Rate and Type in Patients With Urinary Catheter in Intensive Care Unit Unknown status NCT02032394 Phase 4 Povidone-iodine;Chlorhexidine;Normal saline
13 Temocillin Pharmacokinetics in Paediatrics Unknown status NCT02260102 Phase 4 Temocillin
14 Evaluation of the Effectiveness of Antibiotic Prophylaxis in Children With a History of Upper Urinary Tract Infections:a Multicentre Randomised Study Unknown status NCT00156546 Phase 4 antibiotic to reduce the recurrence of infection
15 The Use of Toxin Botulinum A Toxin in Patients With Parkinson's Disease and Multiple System Disease, Affected by Refractory Detrusor Overactivity. Unknown status NCT00822913 Phase 4 Intravesical injection of Botulinum A toxin
16 The Effects of Vaginal Estrogen and a Nonhormonal Alternative on the Vaginal and Urinary Microbiome in Women With Genitourinary Syndrome of Menopause: A Randomized Controlled Trial Unknown status NCT02869165 Phase 4 Premarin vaginal cream;Apricot kernel oil
17 Clinical Impact of Bacteriuria on Chronic Inflammation in Asymptomatic Hemodialysis Patients Unknown status NCT01570556 Phase 4
18 Effectiveness of Bethanechol Chloride and Early Bladder Training for Prevention of Bladder Dysfunction After Radical Hysterectomy in Cervical Cancer Stage IB - IIA Unknown status NCT02910596 Phase 4 bethanechol chloride
19 Functional Electrical Stimulation-Assisted Walking: Reduction of Secondary Complications Due to Spinal Cord Injury Unknown status NCT00201968 Phase 4
20 A Prospective Study Comparing the Success Rate of Injection of Dextranomer /Hyaluronic Acid (DefluxR) Versus Polyacrylate Polyalcohol (VantrisR) for Treatment of Bilateral Similar Grade Vesicoureteral Reflux in Children Unknown status NCT02271035 Phase 4 Deflux;Vantris
21 Impact of Tranexamic Acid Use in Transfusion Rate in Patients With Complex Kidney Stone Undergoing Percutaneous Nephrolithotomy: Randomised, Double-blind, Placebo Controlled Trial Unknown status NCT02966236 Phase 4 Tranexamic Acid;Placebos
22 Effect of Vaginal Estrogen on Asymptomatic Microhematuria (AMH): A Randomized Controlled Trial [EVER Study] Unknown status NCT02213757 Phase 4 Premarin vaginal estrogen cream;Placebo vaginal cream
23 Impact of Antibiotic Treatment Following Implantation of Cardiac Electronic Device on Patient's Outcome Unknown status NCT03148444 Phase 4 cefalexin 500 mg qid or roxithromycin 150 mg bid
24 Granulocyte Colony Stimulating Factor Plus N-Acetyl Cysteine In Severe Alcoholic Hepatitis Unknown status NCT02971306 Phase 4 standard medical therapy;G-CSF;n-Acetylcysteine
25 A Randomized Clinical Trial Between Clindamycin Once and Thrice a Day in Septic Abortion. Unknown status NCT02309346 Phase 4 Clindamycin
26 Comparison of the Efficacy of Triple Therapy With or Without Acetylcysteine in the First Line of Helicobacter Pylori Infection- A Multicenter Randomized Comparative Trial Unknown status NCT02249546 Phase 4 N-acetylcysteine + PPI-amoxicillin-clarithromycin;PPI-amoxicillin-clarithromycin
27 Vaginal Estrogen for the Prevention of Recurrent Urinary Tract Infection in Postmenopausal Women Completed NCT01958073 Phase 4 Conjugated Estrogen Vaginal Cream;Estradiol Ring;Placebo
28 Use of Standardized Delegation Form in Diagnosing and Treating Acute Cystitis in Primary Care Facilities. Completed NCT01132131 Phase 4
29 Clinical and Microbiologic Efficacy of Ciprofloxacin for the Treatment of Uncomplicated Urinary Tract Infection in Adult Women. Completed NCT03366207 Phase 4 Ciprofloxacin
30 Prospective, Open Label Non-comparative, Multi-center Trial to Evaluate the Efficacy and Safety of Cipro® XR 500 mg Once Daily for 3 Days in Treating Female Patients With Acute, Uncomplicated, Symptomatic Lower Urinary Tract Infections Completed NCT00669994 Phase 4 Ciprofloxacin
31 Open Label Study on the Bacteriological and Clinical Efficacy and Safety of a Nitrofurantoin Formulation Given Twice Daily (Bid) for Seven Days in Uncomplicated Urinary Tract Infection in Adults Completed NCT01092351 Phase 4 Nitrofurantoin
32 Cipro® XR Excellence in Therapeutic Response and Activity (eXtRa) - Assessing Symptom Relief in Urinary Tract Infections Completed NCT00676533 Phase 4 Cipro XR (Ciprofloxacin, BAYQ3939)
33 Pharmacokinetics of Ciprofloxacin in Pediatric Patients With Emphasis on Renal Excretion Completed NCT02598362 Phase 4 ciprofloxacin
34 Use of Antibiotic Prophylaxis on Urethral Catheter Withdrawal: A Randomized Double-Blind Placebo-Controlled Trial Completed NCT00126698 Phase 4 trimethoprim-sulfamethoxazole;ciprofloxacin
35 Prospective, Open-Label, Noncomparative, Multicenter Study to Evaluate the Efficacy and Safety of Ciprofloxacin Extended Release (Cipro XR) 1000 mg Tablets Given Once Daily for 7 to 14 Days in the Treatment of Patients 18 Years or Older With Complicated Urinary Tract Infections Caused by Pseudomonas Aeruginosa and Other Common Uropathogens Completed NCT00481689 Phase 4 Cipro XR (Ciprofloxacin, BAYQ3939)
36 Reducing Antibiotic Use for Uncomplicated Urinary Tract Infection in General Practice by Treatment With Uva Ursi (UU)- a Comparative Effectiveness Trial Completed NCT03151603 Phase 4 Arctuvan;Fosfomycin;Placebo to Arctuvan;Placebo to Fosfomycin
37 Immediate vs. Conditional Use of Antibiotics in Uncomplicated Urinary Tract Infection (UTI) - a Comparative Effectiveness Study in General Practice (ICUTI) Completed NCT01488955 Phase 4 Ibuprofen;Fosfomycin-Trometamol
38 Does Prophylaxis With Macrobid Reduce the Incidence of Urinary Tract Infection in Patients Who Receive a Sub-Urethral Sling for the Treatment of Stress Urinary Incontinence: Randomized, Double Blinded Placebo Controlled Clinical Trial Completed NCT00734968 Phase 4 Nitrofurantoin
39 A Randomized, Multicenter, Parallel Group Study to Evaluate Safety and Efficacy of a Weekly Oral Cyclic Antibiotic Programme in the Prevention of Urinary Tract Infection on Neurological Bladder Completed NCT01388413 Phase 4 Weekly Oral Cyclic Antibiotic programme
40 Relevance of Biomarkers and Clinical Predictors of Outcome in Unselected Population With Febrile Urinary Tract Infection at Primary Care and Emergency Department in a Prospective, Randomized Cohort Trial Comparing Short (7 Days) Antibiotic Treatment With Conventional Treatment (14 Days) Completed NCT00809913 Phase 4 short treatment (ciprofloxacin)
41 The Bacteriuria in Renal Transplantation (BiRT) Study: A Prospective, Randomized, Parallel-group, Multicenter, Open-label, Superiority Trial Comparing Antibiotics Versus no Treatment in the Prevention of Symptomatic Urinary Tract Infection in Kidney Transplant Recipients With Asymptomatic Bacteriuria Completed NCT01871753 Phase 4
42 A Randomized, Controlled, Multicentre Trial of Collateral Damage on the Intestinal Microbiota Inferred by Temocillin Versus Cefotaxime in Patients Receiving Empirical Treatment for Febrile Urinary Tract Infections Completed NCT02959957 Phase 4 Temocillin;Cefotaxime
43 Nitrofurantoin Administration for the Prevention of Short-Term Catheter Associated Urinary Tract Infection After Pelvic Surgery (NAUTICA): A Randomized Controlled Trial Completed NCT03287089 Phase 4 Nitrofurantoin 100 MG;Placebo Oral Tablet
44 A Prospective Study on the Usage Patterns of Doripenem in the Asia Pacific Region Completed NCT00986102 Phase 4 doripenem
45 Antibiotic Prophylaxis for Urinary Tract Infection in Patients Requiring Catheterization After Urogynecologic Surgery Completed NCT01450800 Phase 4 Nitrofurantoin;Placebo
46 EXPRESS: Evaluating Cipro XR Patient Response, Education, Safety, and Satisfaction Completed NCT00663806 Phase 4
47 Randomized Controled Multicentric Trial, of Non Inferiority, Comparing Two Durations of Antibiotherapy (5 Days Versus 10 Days) in COMMUNAUTARY Acute Uncomplicated Pyelonephritis. Completed NCT00873626 Phase 4 levofloxacin, ciprofloxacin and ofloxacin (fluoroquinolones)
48 Recurrent Urinary Tract Infections in Children: Bacterial Identification, Antibiotic Susceptibility Profiling and Cytokine Levels Associated With Antibiotic Prophylaxis Completed NCT02357758 Phase 4 Antibiotic Prophylaxis
49 Fosfomycin-Trometamol in Urinary Tract Infection Prophylaxis After Kidney Transplantation. Randomized Controlled Trial. Completed NCT01820897 Phase 4 Fosfomycin-Trometamol;Sulfamethoxazole trimethoprim
50 Antibiotic Treatment for Intermittent Bladder Catheterisation: A Randomised Controlled Trial of Once Daily Prophylaxis Completed NCT02145338 Phase 4 Nitrofurantoin or Trimethoprim or Cefalexin

Search NIH Clinical Center for Acute Cystitis

Inferred drug relations via UMLS 71 / NDF-RT 50 :


acetohydroxamic acid
acetyl sulfisoxazole
Cinoxacin
Ciprofloxacin
Enoxacin
gemifloxacin mesylate
GENTAMICIN SULFATE PWDR
lomefloxacin
Methylene blue
Nitrofurantoin
NITROFURANTOIN, MACROCRYSTALS
Sulfamethizole
Sulfisoxazole
Sulfisoxazole Diolamine
TRIMETHOPRIM SULFATE

Genetic Tests for Acute Cystitis

Anatomical Context for Acute Cystitis

MalaCards organs/tissues related to Acute Cystitis:

40
Kidney, Prostate, Spinal Cord, Testes, Colon, Liver, Neutrophil

Publications for Acute Cystitis

Articles related to Acute Cystitis:

(show top 50) (show all 23044)
# Title Authors PMID Year
1
Catheter-Associated Urinary Tract Infection, Clostridioides difficile Colitis, Central Line-Associated Bloodstream Infection, and Methicillin-Resistant Staphylococcus aureus. 61 42
32505259 2020
2
Surgical Versus Conservative Treatment for Endometrial Cancer in Women of Reproductive Age: Incidence of Urinary Tract Symptoms. 42
32487600 2020
3
Urinary tract infections in children. 42
32446408 2020
4
Discovery and antibacterial study of potential PPK1 inhibitors against uropathogenic E. coli. 61
32420773 2020
5
Non-active antibiotic and bacteriophage synergism to successfully treat recurrent urinary tract infection caused by extensively drug-resistant Klebsiella pneumoniae. 61
32212918 2020
6
Acinetobacter junii as a rare pathogen of urinary tract infection. 61
32322533 2020
7
Unusual presentation of female bladder outlet obstruction- female hypospadias with urethral stenosis. 61
32455118 2020
8
Non-pregnant Women Have a Lower Vitamin D than Pregnant Women After Gastric Bypass. 61
32103434 2020
9
Maximizing the Benefit of Quality Improvement Activities: A Spread of Innovations Model. 61
32433141 2020
10
Innate immunity and urinary tract infection. 61
31197473 2020
11
Risk factors for venous thromboembolism in individuals undergoing coronary artery bypass grafting. 61
31619374 2020
12
Polyethyleneimine-Functionalized Magnetic Fe₃O₄ and Nanodiamond Particles as a Platform for Amoxicillin Delivery. 61
31968409 2020
13
Reanalysis of cefazolin surrogate susceptibility breakpoints utilized as guidances for oral cephalosporin treatments of uncomplicated urinary tract infections: caution concerning application to cefadroxil. 61
32349909 2020
14
Impact of Glycemic Control on Risk of Mortality and Complications in Trauma Patients. 61
31851121 2020
15
Prospective multicenter study of reduced port surgery combined with transvaginal specimen extraction for colorectal cancer resection. 61
31960133 2020
16
Impact of hospital-acquired complications in long-term clinical outcomes after subarachnoid hemorrhage. 61
32480297 2020
17
Blood cultures of adult patients discharged from the emergency department-is the safety net reliable? 61
32052342 2020
18
Prevalence of respiratory viruses and antiviral MxA responses in children with febrile urinary tract infection. 61
32048070 2020
19
Comparison of criteria of International Association of Diabetes and Pregnancy Study Groups (IADPSG) with National Institute for Health and Care Excellence (NICE) for diagnosis of gestational diabetes mellitus. 61
32388777 2020
20
Brazilian consensus on vesicoureteral reflux-recommendations for clinical practice. 61
32167732 2020
21
Prophylaxis of Wound Infections-antibiotics in Renal Donation (POWAR): A UK Multicentre Double Blind Placebo Controlled Randomised Trial. 61
31714309 2020
22
Adult ambulatory otologic surgery: Unplanned revisits and complications. 61
31643096 2020
23
Clinical impact of rapid susceptibility testing on Mueller-Hinton Rapid-SIR directly from urine specimens. 61
32090300 2020
24
The use of tomographic ultrasound imaging on three-dimensional translabial ultrasound: a diagnostic sign for urethral diverticulum. 61
31781823 2020
25
Complications with focus on delirium during hospital stay related to femoral nerve block compared to conventional pain management among patients with hip fracture - A randomised controlled trial. 61
32360090 2020
26
The dose-dependent relationship between blood transfusions and infections after trauma: A population-based study. 61
32102046 2020
27
The impact of perioperative complications on favorable outcomes after artificial urinary sphincter implantation for post-prostatectomy incontinence. 61
32213204 2020
28
Fabrication of Ultra-Pure Anisotropic Zinc Oxide Nanoparticles via Simple and Cost-Effective Route: Implications for UTI and EAC Medications. 61
31529241 2020
29
A systematic review and meta-analysis of antibiotic resistance patterns, and the correlation between biofilm formation with virulence factors in uropathogenic E. coli isolated from urinary tract infections. 61
32283258 2020
30
The effect of early administration of rectal progesterone in IVF/ICSI twin pregnancies on the preterm birth rate: a randomized trial. 61
32517660 2020
31
Vulvovaginal atrophy (VVA) in breast cancer survivors (BCS) is still an unmet medical need: results of an Italian Delphi Panel. 61
31970513 2020
32
Surveillance of common infections in the early period after renal transplantation in a national center: 2014-2017. 61
32037682 2020
33
Gene interaction network approach to elucidate the multidrug resistance mechanisms in the pathogenic bacterial strain Proteus mirabilis. 61
32542649 2020
34
An amphipathic peptide with antibiotic activity against multidrug-resistant Gram-negative bacteria. 61
32576824 2020
35
Combined laparoscopic and transperineal endoscopic total pelvic exenteration for local recurrence of rectal cancer. 61
32236744 2020
36
Re: Indication for Voiding Cystourethrography during First Urinary Tract Infection. 61
32552268 2020
37
Does this patient with urinary tract infection need blood culture? 61
32564060 2020
38
Preoperative Urinary Tract Infection Increases Postoperative Morbidity in Spine Patients. 61
32384411 2020
39
Elixhauser Comorbidity Measure is Superior to Charlson Comorbidity Index In-Predicting Hospital Complications Following Elective Posterior Cervical Decompression and Fusion. 61
32006733 2020
40
A systematic review and meta-analysis of diverting loop ileostomy versus total abdominal colectomy for the treatment of Clostridium difficile colitis. 61
32556579 2020
41
Colorectal Surgical Site Infection Prevention Kits Prior to Elective Colectomy Improve Outcomes. 61
30688687 2020
42
A Phase I Study of Safety, Pharmacokinetics, and Pharmacodynamics of Concurrent Everolimus and Buparlisib Treatment in Advanced Solid Tumors. 61
32005746 2020
43
Antenatally detected urinary tract dilatation: a 12-15-year follow-up. 61
32577807 2020
44
"Urinary Tract Infection" in the Era of COVID-19. 61
32557611 2020
45
Recurrence rate and long-term course of cats with feline lower urinary tract disease. 61
31322040 2020
46
Bacterial spectrum and antibiotic resistance of urinary tract infections in patients treated for upper urinary tract calculi: a multicenter analysis. 61
32557326 2020
47
Spontaneous Incidence of Vertebral Body Infection Following Osteoporotic Vertebral Fracture: A Case Series Study and Review of Literature. 61
31977675 2020
48
Fibroblast Growth Factor 23 and Risk of Hospitalization with Infection in Chronic Kidney Disease: The Chronic Renal Insufficiency Cohort (CRIC) Study. 61
32576601 2020
49
Cranberries after pelvic floor surgery for urinary tract infection prophylaxis: A randomized controlled trial. 61
32449530 2020
50
Re: Impact of Trimethoprim-Sulfamethoxazole Urinary Tract Infection Prophylaxis on Non-UTI Infections. 61
32552271 2020

Variations for Acute Cystitis

Expression for Acute Cystitis

Search GEO for disease gene expression data for Acute Cystitis.

Pathways for Acute Cystitis

Pathways related to Acute Cystitis according to GeneCards Suite gene sharing:

(show all 15)
# Super pathways Score Top Affiliating Genes
1
Show member pathways
13.88 VIM UBAC1 TLR4 SERPINA3 LCN2 INS
2
Show member pathways
12.64 VIM TLR4 IL6 IL18 CCL2
3
Show member pathways
12.16 LCN2 IL6 CXCL1 CCL2
4
Show member pathways
12.15 IL6 IL18 CXCL1 CCL2
5 12.11 TLR4 IL6 IL18 CXCL1 CCL2
6 11.92 VIM INS IL6 ALB
7 11.86 TLR4 IL6 IL18 CCL2
8
Show member pathways
11.77 SERPINA3 INS IL6 CRP CCL2 ALB
9 11.73 VIM TLR4 IL6 CXCL1 CCL2
10 11.61 VIM LCN2 IL6 IL18 CCL2
11 11.49 TLR4 IL6 IL18 CXCL1
12 11.4 TLR4 IL6 IL18 CCL2
13 11.36 IL6 IL18 CXCL1 CCL2
14 11.3 TLR4 KLK3 IL18 CCL2
15 10.99 TLR4 IL6 IL18 CXCL1 CCL2

GO Terms for Acute Cystitis

Cellular components related to Acute Cystitis according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 extracellular exosome GO:0070062 9.85 VIM UPK1A UMOD UBAC1 SLC5A2 SERPINA3
2 extracellular region GO:0005576 9.7 UMOD SERPINA3 LCN2 KLK3 INS IL6
3 extracellular space GO:0005615 9.36 UMOD SERPINA3 LCN2 KLK3 INS IL6

Biological processes related to Acute Cystitis according to GeneCards Suite gene sharing:

(show all 14)
# Name GO ID Score Top Affiliating Genes
1 immune response GO:0006955 9.92 TLR4 IL6 IL18 CXCL1 CCL2
2 cytokine-mediated signaling pathway GO:0019221 9.8 VIM LCN2 IL6 IL18 CXCL1 CCL2
3 positive regulation of gene expression GO:0010628 9.8 VIM TLR4 LCN2 INS IL6 IL18
4 cellular protein metabolic process GO:0044267 9.76 KLK3 INS IL6 ALB
5 positive regulation of NF-kappaB transcription factor activity GO:0051092 9.73 TLR4 INS IL6 IL18
6 cellular response to interferon-gamma GO:0071346 9.67 VIM TLR4 EPRS1 CCL2
7 lipopolysaccharide-mediated signaling pathway GO:0031663 9.58 TLR4 IL18 CCL2
8 positive regulation of neuroinflammatory response GO:0150078 9.54 IL6 IL18
9 negative regulation of blood vessel diameter GO:0097756 9.51 INS CRP
10 inflammatory response GO:0006954 9.5 TLR4 SERPINA3 IL6 IL18 CXCL1 CRP
11 T-helper 1 type immune response GO:0042088 9.49 TLR4 IL18
12 negative regulation of lipid storage GO:0010888 9.48 IL6 CRP
13 acute-phase response GO:0006953 9.46 SERPINA3 INS IL6 CRP
14 cellular response to lipopolysaccharide GO:0071222 9.1 VIM TLR4 LCN2 IL6 CXCL1 CCL2

Molecular functions related to Acute Cystitis according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 cytokine activity GO:0005125 9.46 IL6 IL18 CXCL1 CCL2
2 glucose:sodium symporter activity GO:0005412 8.96 SLC5A4 SLC5A2
3 enterobactin binding GO:1903981 8.62 LCN2 ALB

Sources for Acute Cystitis

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
17 EFO
18 ExPASy
19 FMA
28 GO
29 GTR
30 HMDB
31 HPO
32 ICD10
33 ICD10 via Orphanet
34 ICD9CM
35 IUPHAR
36 KEGG
37 LifeMap
39 LOVD
41 MedGen
43 MeSH
44 MESH via Orphanet
45 MGI
48 NCI
49 NCIt
50 NDF-RT
53 NINDS
54 Novoseek
56 OMIM
57 OMIM via Orphanet
61 PubMed
63 QIAGEN
68 SNOMED-CT via HPO
69 TGDB
70 Tocris
71 UMLS
72 UMLS via Orphanet
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