Aliases & Classifications for Acute Cystitis

MalaCards integrated aliases for Acute Cystitis:

Name: Acute Cystitis 12 15 71 32
Recurrent Urinary Tract Infection 71
Urinary Tract Infections 15
Urinary Tract Infection 71

Classifications:



External Ids:

Disease Ontology 12 DOID:13148
ICD9CM 34 595.0
NCIt 50 C26934
SNOMED-CT 67 197833009
ICD10 32 N30.0
UMLS 71 C0042029 C0149523 C0262655

Summaries for Acute Cystitis

Disease Ontology : 12 A cystitis characterized by a sudden onset or severe symptoms.

MalaCards based summary : Acute Cystitis, also known as recurrent urinary tract infection, is related to disease by infectious agent and ureteral disease, and has symptoms including fever, pruritus and uti symptoms. An important gene associated with Acute Cystitis is IL6 (Interleukin 6), and among its related pathways/superpathways are Innate Immune System and Cytokine Signaling in Immune system. The drugs Acetylcysteine and Lenograstim have been mentioned in the context of this disorder. Affiliated tissues include kidney, spinal cord and prostate, and related phenotypes are adipose tissue and cardiovascular system

Wikipedia : 74 A urinary tract infection (UTI) is an infection that affects part of the urinary tract. When it affects... more...

Related Diseases for Acute Cystitis

Diseases in the Cystitis family:

Acute Cystitis Chronic Cystitis

Diseases related to Acute Cystitis via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50) (show all 782)
# Related Disease Score Top Affiliating Genes
1 disease by infectious agent 32.3 TLR4 IL6 IL18 EPRS1 CRP ALB
2 ureteral disease 32.3 LCN2 IL6 CCL2 ALB
3 polycystic kidney disease 32.2 UMOD LCN2 INS CCL2 ALB
4 autosomal dominant polycystic kidney disease 32.1 VIM LCN2 INS CCL2 ALB
5 cystitis 32.0 VIM UPK1A UMOD TLR4 IL6 IL18
6 neurogenic bladder 31.9 UPK1A KLK3 CRP ALB
7 chronic pyelonephritis 31.7 UMOD TLR4 CRP ALB
8 hydronephrosis 31.6 IL6 CXCL8 CRP CCL2 ALB
9 urolithiasis 31.6 UMOD IL6 ALB
10 urinary tract obstruction 31.6 UMOD LCN2 KLK3 CRP CCL2 ALB
11 constipation 31.5 VIM INS IL6 CRP ALB
12 diarrhea 31.4 TLR4 IL6 CXCL8 ALB
13 urethritis 31.4 TLR4 KLK3 IL6 CXCL8 CRP
14 urinary tract infection 31.3 UMOD TLR4 LCN2 CRP
15 interstitial cystitis 31.3 UPK1A UMOD IL6 CXCL8
16 toxic shock syndrome 31.3 TLR4 IL6 CXCL8 CRP
17 chronic cystitis 31.2 UPK1A TLR4 IL6 CXCL1
18 vaginal discharge 31.2 IL6 CXCL8 CRP ALB
19 end stage renal disease 31.2 UMOD INS IL6 CRP CCL2 ALB
20 chlamydia 31.1 TLR4 IL6 IL18 CXCL8 CRP CCL2
21 interstitial nephritis 31.1 UMOD CRP ALB
22 pneumonia 31.1 TLR4 IL6 IL18 CXCL8 CXCL1 CRP
23 bronchitis 31.1 TLR4 IL6 CXCL8 CRP ALB
24 xanthogranulomatous pyelonephritis 31.0 CRP CCL2
25 neutropenia 31.0 TLR4 IL6 CXCL8 CRP ALB
26 sexual disorder 31.0 KLK3 INS ALB
27 kidney disease 30.9 UMOD LCN2 INS IL6 IL18 CRP
28 diverticulitis 30.9 IL6 CRP ALB
29 acute kidney failure 30.9 UMOD LCN2 IL18 ALB
30 gastroenteritis 30.9 IL6 CXCL8 CRP ALB
31 drug allergy 30.9 OXA1L INS CRP ALB
32 osteomyelitis 30.9 TLR4 IL6 CXCL8 CRP CCL2
33 bacteriuria 30.9 UMOD TLR4 IL6 IL18 CXCL8 CXCL1
34 uremia 30.9 INS IL6 CRP ALB
35 pre-eclampsia 30.9 TLR4 INS IL6 IL18 CXCL8 CRP
36 acute pyelonephritis 30.8 LCN2 IL6 CXCL8 CRP ALB
37 placenta disease 30.8 INS IL6 CXCL8 CRP
38 cerebrovascular disease 30.8 TLR4 INS IL6 CRP
39 anuria 30.8 LCN2 CRP ALB
40 type 2 diabetes mellitus 30.8 TLR4 SLC5A2 LCN2 INS IL6 IL18
41 chronic kidney disease 30.8 UMOD TLR4 SLC5A2 LCN2 INS IL6
42 pyelonephritis 30.8 UMOD TLR4 LCN2 IL6 CXCL8 CRP
43 prostatitis 30.8 KLK3 IL6 CXCL8
44 decubitus ulcer 30.8 INS IL6 CRP ALB
45 liver cirrhosis 30.8 TLR4 INS IL6 CRP ALB
46 polyneuropathy 30.7 INS IL6 CRP ALB
47 multiple sclerosis 30.7 TLR4 IL6 IL18 CXCL8 CXCL1 CCL2
48 otitis media 30.7 TLR4 IL6 CXCL8 CRP ALB
49 pyuria 30.7 LCN2 KLK3 IL6 CXCL8 CRP ALB
50 mental depression 30.7 INS IL6 CRP

Comorbidity relations with Acute Cystitis via Phenotypic Disease Network (PDN): (show top 50) (show all 418)


3-Hydroxyacyl-Coa Dehydrogenase Deficiency Acquired Thrombocytopenia
Active Peptic Ulcer Disease Acute Anterolateral Myocardial Infarction
Acute Conjunctivitis Acute Cor Pulmonale
Acute Kidney Failure Acute Maxillary Sinusitis
Acute Myocardial Infarction Acute Pancreatitis
Acute Sphenoidal Sinusitis Acute Vascular Insufficiency of Intestine
Adjustment Disorder Adrenal Gland Disease
Agammaglobulinemia, X-Linked Age-Related Hearing Loss
Alcoholic Hepatitis Alcoholic Liver Cirrhosis
Alcoholic Neuropathy Algoneurodystrophy
Allergic Urticaria Alopecia, Neurologic Defects, and Endocrinopathy Syndrome
Alzheimer Disease Amnestic Disorder
Amyloidosis Anemia, Autoimmune Hemolytic
Anorexia Nervosa Anus Cancer
Anxiety Aortic Aneurysm
Aortic Atherosclerosis Aortic Valve Disease 1
Asthma Atrioventricular Block
Atrophic Gastritis Atypical Depressive Disorder
Autonomic Nervous System Disease Bacteremia 2
Bacterial Meningitis Balanoposthitis
Basilar Artery Insufficiency Benign Essential Hypertension
Benign Hypertensive Renal Disease Biliary Tract Disease
Bipolar Disorder Bladder Cancer
Bladder Disease Bladder Neck Obstruction
Bleeding Disorder, Platelet-Type, 11 Blepharitis

Graphical network of the top 20 diseases related to Acute Cystitis:



Diseases related to Acute Cystitis

Symptoms & Phenotypes for Acute Cystitis

UMLS symptoms related to Acute Cystitis:


fever, pruritus, uti symptoms

MGI Mouse Phenotypes related to Acute Cystitis:

46
# Description MGI Source Accession Score Top Affiliating Genes
1 adipose tissue MP:0005375 9.76 EPRS1 IL18 IL6 INS LCN2 SLC5A2
2 cardiovascular system MP:0005385 9.7 ALB CRP IL18 IL6 INS KLK3
3 immune system MP:0005387 9.4 ALB CCL2 CD248 CRP IL18 IL6

Drugs & Therapeutics for Acute Cystitis

Drugs for Acute Cystitis (from DrugBank, HMDB, Dgidb, PharmGKB, IUPHAR, NovoSeek, BitterDB):

(show top 50) (show all 361)
# Name Status Phase Clinical Trials Cas Number PubChem Id
1
Acetylcysteine Approved, Investigational Phase 4 616-91-1 12035
2
Lenograstim Approved, Investigational Phase 4 135968-09-1
3
Sargramostim Approved, Investigational Phase 4 123774-72-1, 83869-56-1
4
Pentoxifylline Approved, Investigational Phase 4 6493-05-6 4740
5 Apricot Approved Phase 4
6
Cefixime Approved, Investigational Phase 4 79350-37-1 54362 5362065
7
Vancomycin Approved Phase 4 1404-90-6 441141 14969
8
Zinc Approved, Investigational Phase 4 7440-66-6 32051
9
Doripenem Approved, Investigational Phase 4 148016-81-3 73303
10
Sulbactam Approved Phase 4 68373-14-8
11
Ceftriaxone Approved Phase 4 73384-59-5 5479530 5361919
12
Neomycin Approved, Vet_approved Phase 4 1404-04-2 8378
13
Bacitracin Approved, Vet_approved Phase 4 1405-87-4 439542 10909430
14
Ibuprofen Approved Phase 4 15687-27-1 3672
15
Halofantrine Approved Phase 4 69756-53-2 37393
16
Lactitol Approved, Investigational Phase 4 585-86-4 157355
17
Amoxicillin Approved, Vet_approved Phase 4 26787-78-0 33613
18
Sulfamethoxazole Approved Phase 4 723-46-6 5329
19
Clavulanate Approved, Vet_approved Phase 4 58001-44-8 5280980
20
Ertapenem Approved, Investigational Phase 4 153832-46-3 150610
21
Piperacillin Approved Phase 4 66258-76-2 43672
22
Acetylcholine Approved, Investigational Phase 4 51-84-3 187
23 Sugarcane Approved Phase 4
24
Clindamycin Approved, Vet_approved Phase 4 18323-44-9 29029
25
Methylene blue Approved, Investigational Phase 4 61-73-4
26
Belladonna Approved, Experimental Phase 4
27
Ciprofloxacin Approved, Investigational Phase 4 85721-33-1 2764
28
Amikacin Approved, Investigational, Vet_approved Phase 4 37517-28-5 37768
29
Tobramycin Approved, Investigational Phase 4 32986-56-4 5496 36294
30
Methenamine Approved, Vet_approved Phase 4 100-97-0 4101
31
Fosfomycin Approved Phase 4 23155-02-4 446987
32
Ofloxacin Approved Phase 4 82419-36-1 4583
33
Levofloxacin Approved, Investigational Phase 4 100986-85-4 149096
34
Povidone-iodine Approved Phase 4 25655-41-8
35
Iodine Approved, Investigational Phase 4 7553-56-2 807
36
Povidone Approved Phase 4 9003-39-8 131751496
37
Cilastatin Approved, Investigational Phase 4 82009-34-5 5280454 6435415
38
Imipenem Approved Phase 4 64221-86-9, 74431-23-5 104838
39
Guaifenesin Approved, Investigational, Vet_approved Phase 4 93-14-1 3516
40
Diclofenac Approved, Vet_approved Phase 4 15307-86-5 3033
41
Cefotaxime Approved Phase 4 63527-52-6 456256 5742673
42
Cefoxitin Approved Phase 4 35607-66-0 441199
43
Cysteine Approved, Nutraceutical Phase 4 52-90-4 5862
44
Acriflavine Experimental Phase 4 65589-70-0
45
Cadexomer iodine Experimental Phase 4 94820-09-4
46 N-monoacetylcystine Phase 4
47 Expectorants Phase 4
48 Antidotes Phase 4
49 Solifenacin succinate Phase 4 242478-38-2
50 Cholinergic Antagonists Phase 4

Interventional clinical trials:

(show top 50) (show all 553)
# Name Status NCT ID Phase Drugs
1 Low Dose Estriol With Lactobacilli (Gynoflor) Treatment for Preventing Recurrent Urinary Tract Infection in Postmenopausal Women: A Randomized, Open, Parallel-Group Study Unknown status NCT00900653 Phase 4 Gynoflor E (low dose estriol with lactobacillus)
2 Noroxin Efficacy and Safety Trial Unknown status NCT03506256 Phase 4 Norfloxacin 400 MG
3 Randomised Clinical Trial Comparing Fosfomycin vs. Nitrofurantoin for Treatment of Uncomplicated Lower Urinary Tract Infection in Female Adults at Increased Risk of Antibiotic-resistant Bacterial Infection Unknown status NCT01966653 Phase 4 nitrofurantoin;fosfomycin
4 A Randomised, Double-blind, Placebo Controlled Trial Evaluating the Effectiveness of a Cranberry Concentrate (CranrichTM) in Preventing Recurrent Urinary Tract Infections in Adult Women Unknown status NCT02454309 Phase 4
5 Granulocyte Colony Stimulating Factor Plus N-Acetyl Cysteine In Severe Alcoholic Hepatitis Unknown status NCT02971306 Phase 4 standard medical therapy;G-CSF;n-Acetylcysteine
6 An Open Label Non Placebo Study to Evaluate Efficacy and Safety of Levofloxacin as an Empirical Therapy in Patients With Complicated Urinary Tract Infections Unknown status NCT03160807 Phase 4 Levofloxacin;Levofloxacin
7 Efficacy of Temocillin in Urinary Tract Infection Due to ESBL Producing and AmpC Hyperproducing Enterobacteriaceae Unknown status NCT02681263 Phase 4 Temocillin
8 Randomized Placebo-Controlled Trial of Gentamicin Bladder Instillation for the Prevention of Urinary Tract Infection in Adults at High Risk for Cystitis Due to Intermittent Catheterization Unknown status NCT01884467 Phase 4 Gentamicin;Placebo
9 Evaluation of the Effectiveness of Antibiotic Prophylaxis in Children With a History of Upper Urinary Tract Infections:a Multicentre Randomised Study Unknown status NCT00156546 Phase 4 antibiotic to reduce the recurrence of infection
10 Comparison of the Effect of Applying Povidone-iodine and Chlorhexidine Solutions for Perinea Washing on Bacteriuria Rate and Type in Patients With Urinary Catheter in Intensive Care Unit Unknown status NCT02032394 Phase 4 Povidone-iodine;Chlorhexidine;Normal saline
11 The Impact of Antimicrobial Treatment for Asymptomatic Bacteriuria in Renal Transplant Patients Unknown status NCT02113774 Phase 4
12 The Efficacy of Solifenacin Succinate as Adjuvant Therapy for Symptomatic Non-complicated Urinary Tract Infection in Females Unknown status NCT02094703 Phase 4 Levofloxacin;Solifenacin succinate;Placebo (for Solifenacin succinate)
13 Sanjin Tablets for the Treatment of Acute Simple Lower Urinary Tract Infection and Its Influence on Recurrence Rate: a Randomized, Double Blind, Parallel Control of Positive Drugs, Multi-center Clinical Study Unknown status NCT03658291 Phase 4 Sanjin tablets;Sanjin tablets simulants;Levofloxacin
14 A Open Multi-center Clinical Study on Piperacillin Sodium and Sulbactam Sodium for Injection (2:1) for Treatment of Respiratory and Urinary Tract Infection Unknown status NCT01897831 Phase 4 xin te mie
15 The Effects of Vaginal Estrogen and a Nonhormonal Alternative on the Vaginal and Urinary Microbiome in Women With Genitourinary Syndrome of Menopause: A Randomized Controlled Trial Unknown status NCT02869165 Phase 4 Premarin vaginal cream;Apricot kernel oil
16 Temocillin Pharmacokinetics in Paediatrics Unknown status NCT02260102 Phase 4 Temocillin
17 A Randomized, Multicenter, Parallel Group Study to Evaluate Safety and Efficacy of a Weekly Oral Cyclic Antibiotic Programme in the Prevention of Urinary Tract Infection on Neurological Bladder Completed NCT01388413 Phase 4 Weekly Oral Cyclic Antibiotic programme
18 Open Label Study on the Bacteriological and Clinical Efficacy and Safety of a Nitrofurantoin Formulation Given Twice Daily (Bid) for Seven Days in Uncomplicated Urinary Tract Infection in Adults Completed NCT01092351 Phase 4 Nitrofurantoin
19 Antibiotic Prophylaxis for Urinary Tract Infection in Patients Requiring Catheterization After Urogynecologic Surgery Completed NCT01450800 Phase 4 Nitrofurantoin;Placebo
20 Randomized Controlled Trial of Ultrasound Versus CT (Computed Tomography) for Patients in the Emergency Department With Suspected Renal Colic Completed NCT01451931 Phase 4
21 Vaginal Estrogen for the Prevention of Recurrent Urinary Tract Infection in Postmenopausal Women: A Randomized Clinical Trial Completed NCT01958073 Phase 4 Conjugated Estrogen Vaginal Cream;Estradiol Ring;Placebo
22 Recurrent Urinary Tract Infections in Children: Bacterial Identification, Antibiotic Susceptibility Profiling and Cytokine Levels Associated With Antibiotic Prophylaxis Completed NCT02357758 Phase 4 Antibiotic Prophylaxis
23 Use of Standardized Delegation Form in Diagnosing and Treating Acute Cystitis in Primary Care Facilities. Completed NCT01132131 Phase 4
24 Management of Sub-Clinical Bacteriuria in Pregnancy: A Feasibility Trial Completed NCT03275623 Phase 4 Antibiotic
25 Relevance of Biomarkers and Clinical Predictors of Outcome in Unselected Population With Febrile Urinary Tract Infection at Primary Care and Emergency Department in a Prospective, Randomized Cohort Trial Comparing Short (7 Days) Antibiotic Treatment With Conventional Treatment (14 Days) Completed NCT00809913 Phase 4 short treatment (ciprofloxacin)
26 Acute Effects of Sodium-glucose Cotransporter-2 Inhibition on Renal Oxygenation and Autonomic Function in Type 1 Diabetes Completed NCT04193566 Phase 4 Forxiga
27 Prospective, Open Label Non-comparative, Multi-center Trial to Evaluate the Efficacy and Safety of Cipro® XR 500 mg Once Daily for 3 Days in Treating Female Patients With Acute, Uncomplicated, Symptomatic Lower Urinary Tract Infections Completed NCT00669994 Phase 4 Ciprofloxacin
28 Cipro® XR Excellence in Therapeutic Response and Activity (eXtRa) - Assessing Symptom Relief in Urinary Tract Infections Completed NCT00676533 Phase 4 Cipro XR (Ciprofloxacin, BAYQ3939)
29 Prospective, Open-Label, Noncomparative, Multicenter Study to Evaluate the Efficacy and Safety of Ciprofloxacin Extended Release (Cipro XR) 1000 mg Tablets Given Once Daily for 7 to 14 Days in the Treatment of Patients 18 Years or Older With Complicated Urinary Tract Infections Caused by Pseudomonas Aeruginosa and Other Common Uropathogens Completed NCT00481689 Phase 4 Cipro XR (Ciprofloxacin, BAYQ3939)
30 A Randomized, Controlled, Multicentre Trial of Collateral Damage on the Intestinal Microbiota Inferred by Temocillin Versus Cefotaxime in Patients Receiving Empirical Treatment for Febrile Urinary Tract Infections Completed NCT02959957 Phase 4 Temocillin;Cefotaxime
31 Reducing Antibiotic Use for Uncomplicated Urinary Tract Infection in General Practice by Treatment With Uva Ursi (UU)- a Comparative Effectiveness Trial Completed NCT03151603 Phase 4 Arctuvan;Fosfomycin;Placebo to Arctuvan;Placebo to Fosfomycin
32 Antibiotic Prophylaxis After Acute Pyelonephritis for Prevention of Urinary Tract Infections in Children With Vesico-Ureteral Reflux. Completed NCT00382343 Phase 4 Sulfamethoxazole/trimethoprim
33 Evaluation of Suprapubic Noble Metal Alloy BIP Foley Catheter in the Prevention of Catheter-associated Urinary Tract Infections in Spinal Cord Injured Patients Completed NCT02808000 Phase 4
34 A Post Marketing Surveillance Study on the Safety and Effectiveness of Doripenem in the Therapy of Thai Patients With Nosocomial Pneumonia, Complicated Intra-Abdominal Infections and Complicated Urinary Tract Infections Completed NCT00965848 Phase 4 Doripenem
35 Randomized Controlled Clinical Trial of Efficacy of Fosfomycin Versus Ciprofloxacin as Antibiotic Prophylaxis Prior to Ultrasound Guided Transrectal Prostate Biopsy Completed NCT01803191 Phase 4 Fosfomycin 3 g;Ciprofloxacin 500 mg
36 Antibiotic Treatment for Intermittent Bladder Catheterisation: A Randomised Controlled Trial of Once Daily Prophylaxis Completed NCT02145338 Phase 4 Nitrofurantoin or Trimethoprim or Cefalexin
37 EXPRESS: Evaluating Cipro XR Patient Response, Education, Safety, and Satisfaction Completed NCT00663806 Phase 4
38 Methenamine Hippurate Versus Trimethoprim in the Prevention of Recurrent UTIs Completed NCT03077711 Phase 4 Trimethoprim;Methenamine hippurate
39 Cytoscopic Antibiotic Irrigant to Reduce Postoperative Urinary Infection: A Randomized Controlled Study Completed NCT03099863 Phase 4 Cystoscopic Fluid containing Neosporin G. U. Irrigant;Cystoscopic Fluid/Placebo
40 Pharmacokinetics of Ciprofloxacin in Pediatric Patients With Emphasis on Renal Excretion Completed NCT02598362 Phase 4 ciprofloxacin
41 Fosfomycin-Trometamol in Urinary Tract Infection Prophylaxis After Kidney Transplantation. Randomized Controlled Trial. Completed NCT01820897 Phase 4 Fosfomycin-Trometamol;Sulfamethoxazole trimethoprim
42 Use of Antibiotic Prophylaxis on Urethral Catheter Withdrawal: A Randomized Double-Blind Placebo-Controlled Trial Completed NCT00126698 Phase 4 trimethoprim-sulfamethoxazole;ciprofloxacin
43 Immediate vs. Conditional Use of Antibiotics in Uncomplicated Urinary Tract Infection (UTI) - a Comparative Effectiveness Study in General Practice (ICUTI) Completed NCT01488955 Phase 4 Ibuprofen;Fosfomycin-Trometamol
44 Perioperative Disodium Fosfomycin in the Prophylaxis of Urinary Tract Infection in Kidney Transplant Recipients. Controlled Clinical Trial (PERIFOS Trial) Completed NCT03235947 Phase 4 Fosfomycin disodium;Trimethoprim / Sulfamethoxazole;Intravenous placebo
45 Randomized Controled Multicentric Trial, of Non Inferiority, Comparing Two Durations of Antibiotherapy (5 Days Versus 10 Days) in COMMUNAUTARY Acute Uncomplicated Pyelonephritis. Completed NCT00873626 Phase 4 levofloxacin, ciprofloxacin and ofloxacin (fluoroquinolones)
46 Nitrofurantoin Administration for the Prevention of Short-Term Catheter Associated Urinary Tract Infection After Pelvic Surgery (NAUTICA): A Randomized Controlled Trial Completed NCT03287089 Phase 4 Nitrofurantoin 100 MG;Placebo Oral Tablet
47 Clinical and Microbiologic Efficacy of Ciprofloxacin for the Treatment of Uncomplicated Urinary Tract Infection in Adult Women. Completed NCT03366207 Phase 4 Ciprofloxacin
48 Introduction of Nitrofurantoin in Place of Ciprofloxacin in Patients of Uncomplicated Urinary Tract Infection: a Controlled Clinical Trial to Establish the Relationship Between Revival and Associated Shift in Sensitivity Pattern of the Causative Microbes Completed NCT03716804 Phase 4 Tablet Nitrofurantoin;Tablet Ciprofloxacin/ Tablet Cefixime/ Tablet Cefuroxime
49 The Bacteriuria in Renal Transplantation (BiRT) Study: A Prospective, Randomized, Parallel-group, Multicenter, Open-label, Superiority Trial Comparing Antibiotics Versus no Treatment in the Prevention of Symptomatic Urinary Tract Infection in Kidney Transplant Recipients With Asymptomatic Bacteriuria Completed NCT01871753 Phase 4
50 Does Prophylaxis With Macrobid Reduce the Incidence of Urinary Tract Infection in Patients Who Receive a Sub-Urethral Sling for the Treatment of Stress Urinary Incontinence: Randomized, Double Blinded Placebo Controlled Clinical Trial Completed NCT00734968 Phase 4 Nitrofurantoin

Search NIH Clinical Center for Acute Cystitis

Inferred drug relations via UMLS 71 / NDF-RT 51 :


acetohydroxamic acid
acetyl sulfisoxazole
Cinoxacin
Ciprofloxacin
Enoxacin
gemifloxacin mesylate
GENTAMICIN SULFATE PWDR
lomefloxacin
Methylene blue
Nitrofurantoin
NITROFURANTOIN, MACROCRYSTALS
Sulfamethizole
Sulfisoxazole
Sulfisoxazole Diolamine
TRIMETHOPRIM SULFATE

Genetic Tests for Acute Cystitis

Anatomical Context for Acute Cystitis

MalaCards organs/tissues related to Acute Cystitis:

40
Kidney, Spinal Cord, Prostate, Skin, Neutrophil, Pancreas, Brain

Publications for Acute Cystitis

Articles related to Acute Cystitis:

(show top 50) (show all 22297)
# Title Authors PMID Year
1
Clinical profile of a Polish cohort of children and young adults with cystinuria. 61
33349102 2021
2
A randomized, active-controlled, multicentre clinical trial to evaluate the efficacy and safety of oral sitafloxacin versus levofloxacin in Chinese adults with acute uncomplicated or complicated urinary tract infection. 61
33331182 2021
3
Phylogenetic Group B2 Expressed Significant Biofilm Formation among Drug Resistant Uropathogenic Escherichia coli. 61
33170767 2021
4
Isolation, characterization and antibiotic resistance of Proteus mirabilis from Belgian broiler carcasses at retail and human stool. 61
33494897 2021
5
Biocompatibility and stability during storage of Foley urinary catheters coated chlorhexidine loaded nanoparticles by nanocoating: in vitro and in vivo evaluation. 61
32918382 2021
6
The risk of infection in patients with multiple sclerosis treated with disease-modifying therapies: A Delphi consensus statement. 61
32940121 2021
7
Polysaccharides extract from Vaccaria segetalis seeds inhibits kidney infection by regulating cathelicidin expression. 61
33141055 2021
8
Recurrent neurosurgical site infection by extensively drug-resistant P. aeruginosa treated with cefiderocol: a case report and literature review. 61
33295821 2021
9
Correction to: Swiss consensus recommendations on urinary tract infections in children. 61
33001233 2021
10
Procalcitonin as a predictor of early antibiotic treatment failure in patients with gram-negative bloodstream infections caused by urinary tract infections. 61
33220639 2021
11
Management of Urologic Conditions in Small Ruminants. 61
33358314 2021
12
Swiss consensus recommendations on urinary tract infections in children. 61
32621135 2021
13
Acute kidney injury in patients hospitalized with febrile urinary tract infections: A prospective observational study. 61
33355088 2021
14
The microbiome in urinary tract infections in children - an update. 61
33449574 2021
15
Intravesical acetic acid in combination with prophylactic methenamine and ascorbic acid to decrease the incidence of recurrent urinary tract infections associated with intermittent urinary self-catherization: A case report. 61
33365254 2021
16
Comparative Effectiveness and Safety of Sodium-Glucose Cotransporter 2 Inhibitors Versus Glucagon-Like Peptide 1 Receptor Agonists in Older Adults. 61
33495295 2021
17
Sex effects in pyelonephritis. 61
32040629 2021
18
Real-world experience of ocrelizumab in multiple sclerosis in a Spanish population. 61
33369288 2021
19
Safety and effectiveness of tofogliflozin in Japanese patients with type 2 diabetes mellitus treated in real-world clinical practice: Results of a 36-month post-marketing surveillance study (J-STEP/LT). 61
32597517 2021
20
Triggering of cardiovascular disease by infection type: The Atherosclerosis Risk in Communities study (ARIC). 61
33031889 2021
21
Applications of microcapillary films in bioanalytical techniques. 61
33528470 2021
22
Efficacy and safety of cefiderocol or best available therapy for the treatment of serious infections caused by carbapenem-resistant Gram-negative bacteria (CREDIBLE-CR): a randomised, open-label, multicentre, pathogen-focused, descriptive, phase 3 trial. 61
33058795 2021
23
Weak organic acid synergy towards the prevention of catheter blockages. 61
33545216 2021
24
Association of Medicaid Expansion With Quality in Safety-Net Hospitals. 61
33587092 2021
25
Efficacy of temocillin against MDR Enterobacterales: a retrospective cohort study. 61
33254232 2021
26
Changes in Bacterial Spectrum and Resistance Patterns Over Time in the Urine of Patients with Neurogenic Lower Urinary Tract Dysfunction Due to Spinal Cord Injury. 61
33567445 2021
27
Synergistic activity of weak organic acids against uropathogens. 61
33545217 2021
28
The Effect of Phenazopyridine on Immediate Postoperative Voiding After Prolapse Surgery: A Randomized Controlled Trial. 61
31033527 2021
29
Does targeting Arg98 of FimH lead to high affinity antagonists? 61
33340913 2021
30
Treatment of uncomplicated UTI in males: a systematic review of the literature. 61
33234514 2021
31
Embryology of the urogenital tract; a practical overview for urogynecologic surgeons. 61
33123766 2021
32
Covalent capture and electrochemical quantification of pathogenic E. coli. 61
33585846 2021
33
Comparison of a magnetic retrieval device vs. flexible cystoscopy for removal of ureteral stents in renal transplant patients: A randomized controlled trial. 61
32745000 2021
34
Imipenem/cilastatin/relebactam: A new carbapenem β-lactamase inhibitor combination. 61
33580649 2021
35
Clinical Outcomes of Patient Subgroups in the TANGO II Study. 61
33565042 2021
36
An evaluation of meropenem/vaborbactam for the treatment of nosocomial pneumonia. 61
33090037 2021
37
Revision and complication rates in adult shunt surgery: a single-institution study. 61
33130985 2021
38
[Acute care interventions in inpatient neurorehabilitation]. 61
33125513 2021
39
Bacterial Infections in Cirrhotic Patients in a Tertiary Care Hospital. 61
33604253 2021
40
An update on cefepime and its future role in combination with novel β-lactamase inhibitors for MDR Enterobacterales and Pseudomonas aeruginosa. 61
33332545 2021
41
Urotherapist activities in caring for patients with pelvic floor disorders: a prospective single-center observational study. 61
33000294 2021
42
A rapid, antibiotic susceptibility test for multidrug-resistant, Gram-negative bacterial uropathogens using the biochemical assay, DETECT. 61
33548393 2021
43
Infection-Triggered, Self-Cleaning Surfaces with On-Demand Cleavage of Surface-Localized Surfactant Moieties. 61
33502846 2021
44
Uromodulin: Roles in Health and Disease. 61
33566673 2021
45
Oral antibiotic bowel decontamination in open and laparoscopic sigmoid resections for diverticular disease. 61
33606074 2021
46
Antibiotic prescribing for adult bacteriuria and pyuria in community hospital emergency departments. 61
33326910 2021
47
Propeller Flap Perineal Urethrostomy Revision. 61
33309704 2021
48
[Antibiotic prophylaxis for endourological interventions considering antibiotic stewardship]. 61
33560463 2021
49
Self-Reported Urological Hospitalizations or Emergency Room Visits in a Contemporary Spinal Cord Injury Cohort. 61
33035138 2021
50
Prevalence of Cognitive Impairment and Sphincter Misuse Among Men With Artificial Urinary Sphincters. 61
33115618 2021

Variations for Acute Cystitis

Expression for Acute Cystitis

Search GEO for disease gene expression data for Acute Cystitis.

Pathways for Acute Cystitis

Pathways related to Acute Cystitis according to GeneCards Suite gene sharing:

(show all 26)
# Super pathways Score Top Affiliating Genes
1
Show member pathways
13.96 VIM UBAC1 TLR4 LCN2 INS IL6
2
Show member pathways
13.28 VIM LCN2 IL6 IL18 CXCL8 CXCL1
3
Show member pathways
12.75 VIM TLR4 IL6 IL18 CXCL8 CCL2
4
Show member pathways
12.26 LCN2 IL6 CXCL8 CXCL1 CCL2
5
Show member pathways
12.24 IL6 IL18 CXCL8 CXCL1 CCL2
6
Show member pathways
12.23 INS IL6 CRP CCL2 ALB
7 12.14 TLR4 IL6 IL18 CXCL8 CXCL1 CCL2
8 12.02 VIM INS IL6 ALB
9 11.99 TLR4 IL6 IL18 CXCL8 CCL2
10 11.88 INS IL6 CXCL8 CXCL1
11 11.86 TLR4 IL6 CXCL8 CXCL1
12
Show member pathways
11.81 TLR4 IL6 CXCL8 CXCL1
13 11.71 VIM TLR4 IL6 CXCL8 CXCL1 CCL2
14
Show member pathways
11.67 TLR4 IL6 IL18
15 11.67 TLR4 IL6 CXCL8
16 11.58 IL6 CXCL8 CCL2
17 11.52 TLR4 IL6 IL18 CXCL8 CXCL1
18 11.51 INS IL6 CXCL8
19 11.49 VIM LCN2 IL6 IL18 CXCL8 CCL2
20 11.42 TLR4 KLK3 IL18 CCL2
21 11.42 TLR4 IL6 IL18 CXCL8 CCL2
22 11.34 IL6 IL18 CXCL8 CXCL1 CCL2
23 11.28 IL6 CXCL8 CCL2
24 11.07 TLR4 IL6 IL18 CXCL8 CXCL1 CCL2
25 10.96 VIM IL6 IL18 CXCL8 CXCL1 CCL2
26 10.93 IL6 CXCL8 CRP

GO Terms for Acute Cystitis

Cellular components related to Acute Cystitis according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 extracellular exosome GO:0070062 9.81 VIM UPK1A UMOD UBAC1 SLC5A2 LCN2
2 extracellular region GO:0005576 9.7 UMOD LCN2 KLK3 INS IL6 IL18
3 extracellular space GO:0005615 9.36 UMOD LCN2 KLK3 INS IL6 IL18

Biological processes related to Acute Cystitis according to GeneCards Suite gene sharing:

(show all 17)
# Name GO ID Score Top Affiliating Genes
1 positive regulation of gene expression GO:0010628 9.86 VIM TLR4 LCN2 INS IL6 IL18
2 immune response GO:0006955 9.85 TLR4 IL6 IL18 CXCL8 CXCL1 CCL2
3 cellular protein metabolic process GO:0044267 9.81 KLK3 INS IL6 ALB
4 positive regulation of NF-kappaB transcription factor activity GO:0051092 9.76 TLR4 INS IL6 IL18
5 defense response to Gram-negative bacterium GO:0050829 9.73 UMOD TLR4 IL6
6 cellular response to interleukin-1 GO:0071347 9.72 LCN2 CXCL8 CCL2
7 neutrophil chemotaxis GO:0030593 9.71 CXCL8 CXCL1 CCL2
8 cytokine-mediated signaling pathway GO:0019221 9.7 VIM LCN2 IL6 IL18 CXCL8 CXCL1
9 chemokine-mediated signaling pathway GO:0070098 9.67 CXCL8 CXCL1 CCL2
10 cellular response to interferon-gamma GO:0071346 9.62 VIM TLR4 EPRS1 CCL2
11 acute-phase response GO:0006953 9.61 INS IL6 CRP
12 lipopolysaccharide-mediated signaling pathway GO:0031663 9.58 TLR4 IL18 CCL2
13 positive regulation of neuroinflammatory response GO:0150078 9.57 IL6 IL18
14 inflammatory response GO:0006954 9.56 UMOD TLR4 IL6 IL18 CXCL8 CXCL1
15 T-helper 1 type immune response GO:0042088 9.52 TLR4 IL18
16 negative regulation of lipid storage GO:0010888 9.48 IL6 CRP
17 cellular response to lipopolysaccharide GO:0071222 9.17 VIM TLR4 LCN2 IL6 CXCL8 CXCL1

Molecular functions related to Acute Cystitis according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 chemokine activity GO:0008009 9.33 CXCL8 CXCL1 CCL2
2 glucose:sodium symporter activity GO:0005412 9.26 SLC5A4 SLC5A2
3 cytokine activity GO:0005125 9.02 IL6 IL18 CXCL8 CXCL1 CCL2
4 enterobactin binding GO:1903981 8.96 LCN2 ALB

Sources for Acute Cystitis

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
17 EFO
18 ExPASy
19 FMA
20 GARD
28 GO
29 GTR
30 HMDB
31 HPO
32 ICD10
33 ICD10 via Orphanet
34 ICD9CM
35 IUPHAR
36 KEGG
37 LifeMap
39 LOVD
41 MedGen
44 MeSH
45 MESH via Orphanet
46 MGI
49 NCI
50 NCIt
51 NDF-RT
53 NINDS
54 Novoseek
56 OMIM via Orphanet
57 OMIM® (Updated 05-Mar-2021)
61 PubMed
63 QIAGEN
68 SNOMED-CT via HPO
69 TGDB
70 Tocris
71 UMLS
72 UMLS via Orphanet
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