MCID: ACT037
MIFTS: 37

Acute Dacryocystitis

Categories: Eye diseases

Aliases & Classifications for Acute Dacryocystitis

MalaCards integrated aliases for Acute Dacryocystitis:

Name: Acute Dacryocystitis 12 15 73
Dacryocystitis - Acute 12

Classifications:



External Ids:

Disease Ontology 12 DOID:12996
ICD10 33 H04.32
ICD9CM 35 375.32
SNOMED-CT 68 25470000
UMLS 73 C0155237

Summaries for Acute Dacryocystitis

MalaCards based summary : Acute Dacryocystitis, also known as dacryocystitis - acute, is related to dacryocystitis and sporotrichosis. An important gene associated with Acute Dacryocystitis is DCXR (Dicarbonyl And L-Xylulose Reductase), and among its related pathways/superpathways are Glycosaminoglycan metabolism and Aquaporin-mediated transport. The drug Calamus has been mentioned in the context of this disorder. Affiliated tissues include eye and b cells, and related phenotype is Reduced mammosphere formation.

Related Diseases for Acute Dacryocystitis

Diseases in the Dacryocystitis family:

Acute Dacryocystitis Chronic Dacryocystitis

Diseases related to Acute Dacryocystitis via text searches within MalaCards or GeneCards Suite gene sharing:

(show all 49)
# Related Disease Score Top Affiliating Genes
1 dacryocystitis 31.5 ALG10B DCXR
2 sporotrichosis 29.7 CALM1 CALM2 CALM3
3 chronic dacryocystitis 29.1 ALG10 ALG10B AVIL DCXR TNN
4 dacryoadenitis 10.3
5 lacrimal duct defect 10.1
6 orbital cellulitis 10.1
7 cellulitis 10.1
8 acute inflammation of lacrimal passage 10.0 ALG10B DCXR
9 lymphoma 10.0
10 dacryocystocele 10.0
11 long qt syndrome 1 10.0 CALM1 CALM2 CALM3
12 long qt syndrome 15 10.0 CALM1 CALM2 CALM3
13 otomycosis 10.0 CALM1 CALM2 CALM3
14 external ear disease 10.0 CALM1 CALM2 CALM3
15 emery-dreifuss muscular dystrophy 5, autosomal dominant 10.0 CALM1 CALM2 CALM3
16 otitis externa 10.0 CALM1 CALM2 CALM3
17 spontaneous ocular nystagmus 10.0 CALM1 CALM2 CALM3
18 deafness, autosomal recessive 44 10.0 CALM1 CALM2 CALM3
19 dystonia 24 10.0 CALM1 CALM2 CALM3
20 gestational choriocarcinoma 9.9 CALM1 CALM2 CALM3
21 triosephosphate isomerase deficiency 9.9 CALM1 CALM2 CALM3
22 leber congenital amaurosis 2 9.9 CALM1 CALM2 CALM3
23 tinea unguium 9.9 CALM1 CALM2 CALM3
24 primary systemic mycosis 9.9 CALM1 CALM2 CALM3
25 clear cell acanthoma 9.9 CALM1 CALM2 CALM3
26 cardiomyopathy, dilated, 1a 9.9 CALM1 CALM2 CALM3
27 cardiomyopathy, dilated, 1p 9.9 CALM1 CALM2 CALM3
28 phaeohyphomycosis 9.9 CALM1 CALM2 CALM3
29 deafness, autosomal dominant 2a 9.9 CALM1 CALM2 CALM3
30 microcephaly 2, primary, autosomal recessive, with or without cortical malformations 9.9 CALM1 CALM2 CALM3
31 ceroid lipofuscinosis, neuronal, 11 9.9 CALM1 CALM2 CALM3
32 primary cutaneous amyloidosis 9.9 CALM1 CALM2 CALM3
33 hepatocellular carcinoma 9.9
34 leukemia 9.9
35 keratoconjunctivitis sicca 9.9
36 oculoglandular tularemia 9.9
37 squamous cell carcinoma 9.9
38 tularemia 9.9
39 rhabdomyosarcoma 9.9
40 rhinitis 9.9
41 viral infectious disease 9.9
42 keratoconjunctivitis 9.9
43 fasciitis 9.9
44 necrotizing fasciitis 9.9
45 catecholaminergic polymorphic ventricular tachycardia 9.9 CALM1 CALM2 CALM3
46 cardiac arrest 9.8 CALM1 CALM2 CALM3
47 dental anomalies and short stature 9.8 ALG10B AVIL
48 long qt syndrome 9.6 ALG10 ALG10B CALM1 CALM2 CALM3
49 chronic inflammation of lacrimal passage 9.6 ALG10 ALG10B AVIL DCXR TNN

Comorbidity relations with Acute Dacryocystitis via Phenotypic Disease Network (PDN):


Orbital Cellulitis

Graphical network of the top 20 diseases related to Acute Dacryocystitis:



Diseases related to Acute Dacryocystitis

Symptoms & Phenotypes for Acute Dacryocystitis

GenomeRNAi Phenotypes related to Acute Dacryocystitis according to GeneCards Suite gene sharing:

26
# Description GenomeRNAi Source Accession Score Top Affiliating Genes
1 Reduced mammosphere formation GR00396-S 9.02 ALG10B CALM1 CALM2 CALM3 DCXR

Drugs & Therapeutics for Acute Dacryocystitis

Drugs for Acute Dacryocystitis (from DrugBank, HMDB, Dgidb, PharmGKB, IUPHAR, NovoSeek, BitterDB):


# Name Status Phase Clinical Trials Cas Number PubChem Id
1 Calamus Not Applicable

Interventional clinical trials:


# Name Status NCT ID Phase Drugs
1 The Microbiological Spectrum in Acute Dacryocystitis Completed NCT00349297
2 Endoscopy Assisted Probing Versus Simple Probing in Primary Congenital Nasolacrimal Duct Obstruction Recruiting NCT03242681 Not Applicable

Search NIH Clinical Center for Acute Dacryocystitis

Genetic Tests for Acute Dacryocystitis

Anatomical Context for Acute Dacryocystitis

MalaCards organs/tissues related to Acute Dacryocystitis:

41
Eye, B Cells

Publications for Acute Dacryocystitis

Articles related to Acute Dacryocystitis:

(show top 50) (show all 65)
# Title Authors Year
1
A Neonate With Acute Dacryocystitis. ( 28973285 )
2018
2
Acute Dacryocystitis. ( 30067930 )
2018
3
Acute dacryocystitis complicated by orbital cellulitis and loss of vision: A case report and review of the literature. ( 30118963 )
2018
4
Metastatic hepatocellular carcinoma mimicking acute dacryocystitis. ( 30119803 )
2018
5
Odontogenic abscess mimicking acute dacryocystitis. ( 28455457 )
2017
6
Success Rate of Conventional Dacryocystorhinostomy in Post-acute Dacryocystitis Compared to Endonasal Dacryocystorhinostomy in Acute Dacryocystitis. ( 28791062 )
2017
7
Clinical Outcome of Probing in Infants with Acute Dacryocystitis - A Prospective Study. ( 28969168 )
2017
8
Primary vs Secondary Endoscopic Dacryocystorhinostomy for Acute Dacryocystitis With Lacrimal Sac Abscess Formation: A Randomized Clinical Trial. ( 29121183 )
2017
9
Re: "Pediatric Acute Dacryocystitis". ( 26953972 )
2016
10
Primary Nonendoscopic Endonasal Versus Delayed External Dacryocystorhinostomy in Acute Dacryocystitis. ( 27505272 )
2016
11
Complete Vision Loss following Orbital Cellulitis Secondary to Acute Dacryocystitis. ( 27803829 )
2016
12
Long-term outcomes of powered endoscopic dacryocystorhinostomy in acute dacryocystitis. ( 25994372 )
2016
13
Reply re: "Pediatric Acute Dacryocystitis". ( 26953973 )
2016
14
Microbiology of primary acquired nasolacrimal duct obstruction: simple epiphora, acute dacryocystitis, and chronic dacryocystitis. ( 26955261 )
2016
15
Pediatric Acute Dacryocystitis. ( 25856337 )
2015
16
Acute dacryocystitis as a presenting sign of chronic lymphocytic leukaemia. ( 26183368 )
2015
17
Acute dacryocystitis: another clinical manifestation of sporotrichosis. ( 24810176 )
2014
18
Primary Powered Endoscopic Dacryocystorhinostomy in the Setting of Acute Dacryocystitis and Lacrimal Abscess. ( 25226100 )
2014
19
Dacryolith-induced acute dacryocystitis: a reversible cause of nasolacrimal duct obstruction. ( 24568662 )
2014
20
Acute Dacryocystitis with Empyema of the Lacrimal Sac: Is Immediate Endoscopic Dacryocystorhinostomy Justified? ( 24647640 )
2014
21
Cardiobacterium hominis -induced acute dacryocystitis and lacrimal abscess. ( 24008805 )
2013
22
Unilateral acute dacryocystitis associated with oculoglandular tularemia: a case report. ( 23448564 )
2013
23
Clinical Profile and Management Outcome of Acute Dacryocystitis: Two Decades of Experience in a Tertiary Eye Care Center. ( 24171807 )
2013
24
Acute dacryocystitis in a 2-year old child caused by pantoea. ( 22296230 )
2012
25
Community-acquired methicillin-resistant Staphylococcus aureus bilateral acute dacryocystitis in a neonate. ( 22446919 )
2012
26
Endoscopic dacryocystorhinostomy in acute dacryocystitis: a multicenter case series. ( 21281068 )
2011
27
Acute dacryocystitis associated with epstein-barr virus infection. ( 21957956 )
2011
28
Enlarging red swelling below the right eye. What's your diagnosis? Diagnosis: Congenital dacryocystocele with acute dacryocystitis. ( 20349896 )
2010
29
An uncommon complication of septorhinoplasty, acute dacryocystitis. ( 19756855 )
2010
30
Primary treatment of acute dacryocystitis by endoscopic dacryocystorhinostomy with silicone intubation guided by a soft probe. ( 19118702 )
2009
31
Acute dacryocystitis causing orbital cellulitis and abscess. ( 19839913 )
2009
32
Congenital lacrimal system anomalies mimicking recurrent acute dacryocystitis. ( 18209645 )
2008
33
Primary endoscopic dacryocystorhinostomy as treatment for acute dacryocystitis with abscess formation. ( 18439951 )
2008
34
Orbital abscess secondary to acute dacryocystitis: case report. ( 18797671 )
2008
35
A silastic sheet found during endoscopic transnasal dacryocystorhinostomy for acute dacryocystitis. ( 16768193 )
2006
36
Congenital dacryocystocele with acute dacryocystitis: report of two cases. ( 17016968 )
2006
37
Rhabdomyosarcoma masquerading as acute dacryocystitis. ( 16304528 )
2005
38
Squamous cell carcinoma of the frontal and ethmoidal paranasal sinuses masquerading as acute dacryocystitis. ( 14765102 )
2004
39
The treatment of acute dacryocystitis using laser assisted endonasal dacryocystorhinostomy. ( 14693791 )
2004
40
Primary lacrimal sac B-cell immunoblastic lymphoma simulating an acute dacryocystitis. ( 12868025 )
2003
41
Facial necrotizing fasciitis following acute dacryocystitis. ( 12834700 )
2003
42
Acute dacryocystitis presenting as an orbital abscess. ( 11885795 )
2002
43
Endonasal dacryocystorhinostomy in the primary treatment of acute dacryocystitis with abscess formation. ( 11388383 )
2001
44
Acute dacryocystitis as a presenting sign of pediatric leukemia. ( 10372893 )
1999
45
An orbital abscess secondary to acute dacryocystitis. ( 9304639 )
1997
46
Orbital abscess secondary to acute dacryocystitis. ( 8804761 )
1996
47
Acute dacryocystitis: an unusual cause of life-threatening orbital intraconal abscess with frozen globe. ( 8944391 )
1996
48
Nasolacrimal duct obstruction and acute dacryocystitis associated with infectious mononucleosis (Epstein-Barr virus) ( 8381586 )
1993
49
Acute dacryocystitis secondary to exudative rhinitis. ( 8382941 )
1993
50
Management of acute dacryocystitis in adults. ( 8443113 )
1993

Variations for Acute Dacryocystitis

Expression for Acute Dacryocystitis

Search GEO for disease gene expression data for Acute Dacryocystitis.

Pathways for Acute Dacryocystitis

Pathways related to Acute Dacryocystitis according to GeneCards Suite gene sharing:

(show top 50) (show all 75)
# Super pathways Score Top Affiliating Genes
1
Show member pathways
12.77 CALM1 CALM2 CALM3 DCXR
2
Show member pathways
12.34 CALM1 CALM2 CALM3
3
Show member pathways
12.34 CALM1 CALM2 CALM3
4
Show member pathways
12.33 CALM1 CALM2 CALM3
5
Show member pathways
12.32 CALM1 CALM2 CALM3
6
Show member pathways
12.32 CALM1 CALM2 CALM3
7
Show member pathways
12.3 CALM1 CALM2 CALM3
8
Show member pathways
12.29 CALM1 CALM2 CALM3
9
Show member pathways
12.28 CALM1 CALM2 CALM3
10 12.26 CALM1 CALM2 CALM3
11
Show member pathways
12.25 CALM1 CALM2 CALM3
12
Show member pathways
12.25 CALM1 CALM2 CALM3
13
Show member pathways
12.23 CALM1 CALM2 CALM3
14
Show member pathways
12.23 CALM1 CALM2 CALM3
15
Show member pathways
12.22 CALM1 CALM2 CALM3
16
Show member pathways
12.22 CALM1 CALM2 CALM3
17
Show member pathways
12.2 CALM1 CALM2 CALM3
18
Show member pathways
12.16 CALM1 CALM2 CALM3
19
Show member pathways
12.16 CALM1 CALM2 CALM3
20
Show member pathways
12.14 CALM1 CALM2 CALM3
21 12.13 CALM1 CALM2 CALM3
22
Show member pathways
12.11 CALM1 CALM2 CALM3
23
Show member pathways
12.11 CALM1 CALM2 CALM3
24
Show member pathways
12.09 CALM1 CALM2 CALM3
25
Show member pathways
12.08 CALM1 CALM2 CALM3
26
Show member pathways
12.06 CALM1 CALM2 CALM3
27 12.06 CALM1 CALM2 CALM3
28
Show member pathways
12.05 CALM1 CALM2 CALM3
29
Show member pathways
12.03 CALM1 CALM2 CALM3
30 11.99 CALM1 CALM2 CALM3
31 11.98 CALM1 CALM2 CALM3
32
Show member pathways
11.92 CALM1 CALM2 CALM3
33
Show member pathways
11.9 CALM1 CALM2 CALM3
34
Show member pathways
11.87 CALM1 CALM2 CALM3
35
Show member pathways
11.84 CALM1 CALM2 CALM3
36 11.83 CALM1 CALM2 CALM3
37 11.82 CALM1 CALM2 CALM3
38 11.8 CALM1 CALM2 CALM3
39
Show member pathways
11.79 CALM1 CALM2 CALM3
40
Show member pathways
11.76 CALM1 CALM2 CALM3
41
Show member pathways
11.75 CALM1 CALM2 CALM3
42
Show member pathways
11.68 CALM1 CALM2 CALM3
43
Show member pathways
11.67 CALM1 CALM2 CALM3
44
Show member pathways
11.66 CALM1 CALM2 CALM3
45 11.65 CALM1 CALM2 CALM3
46
Show member pathways
11.64 CALM1 CALM2 CALM3
47 11.62 CALM1 CALM2 CALM3
48
Show member pathways
11.57 CALM1 CALM2 CALM3
49 11.55 CALM1 CALM2 CALM3
50 11.52 CALM1 CALM2 CALM3

GO Terms for Acute Dacryocystitis

Cellular components related to Acute Dacryocystitis according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 neuron projection GO:0043005 9.67 AVIL CALM1 CALM3 TNN
2 spindle GO:0005819 9.63 CALM1 CALM2 CALM3
3 vesicle GO:0031982 9.61 CALM1 CALM2 CALM3
4 myelin sheath GO:0043209 9.58 CALM1 CALM2 CALM3
5 spindle pole GO:0000922 9.5 CALM1 CALM2 CALM3
6 sarcomere GO:0030017 9.43 CALM1 CALM2 CALM3
7 spindle microtubule GO:0005876 9.33 CALM1 CALM2 CALM3
8 calcium channel complex GO:0034704 9.13 CALM1 CALM2 CALM3
9 catalytic complex GO:1902494 8.8 CALM1 CALM2 CALM3

Biological processes related to Acute Dacryocystitis according to GeneCards Suite gene sharing:

(show all 32)
# Name GO ID Score Top Affiliating Genes
1 phosphorylation GO:0016310 9.96 CALM1 CALM2 CALM3 TAOK3
2 calcium-mediated signaling GO:0019722 9.78 CALM1 CALM2 CALM3
3 response to calcium ion GO:0051592 9.77 CALM1 CALM2 CALM3
4 positive regulation of protein serine/threonine kinase activity GO:0071902 9.76 CALM1 CALM2 CALM3
5 substantia nigra development GO:0021762 9.75 CALM1 CALM2 CALM3
6 regulation of cytokinesis GO:0032465 9.74 CALM1 CALM2 CALM3
7 regulation of heart rate GO:0002027 9.73 CALM1 CALM2 CALM3
8 positive regulation of peptidyl-threonine phosphorylation GO:0010800 9.71 CALM1 CALM2 CALM3
9 positive regulation of protein dephosphorylation GO:0035307 9.7 CALM1 CALM2 CALM3
10 positive regulation of protein autophosphorylation GO:0031954 9.69 CALM1 CALM2 CALM3
11 regulation of cardiac muscle contraction by regulation of the release of sequestered calcium ion GO:0010881 9.67 CALM1 CALM2 CALM3
12 response to amphetamine GO:0001975 9.65 CALM1 CALM3
13 activation of adenylate cyclase activity GO:0007190 9.65 CALM1 CALM3
14 regulation of release of sequestered calcium ion into cytosol by sarcoplasmic reticulum GO:0010880 9.65 CALM1 CALM2 CALM3
15 positive regulation of DNA binding GO:0043388 9.64 CALM2 CALM3
16 positive regulation of nitric-oxide synthase activity GO:0051000 9.64 CALM1 CALM3
17 response to corticosterone GO:0051412 9.63 CALM1 CALM3
18 regulation of ryanodine-sensitive calcium-release channel activity GO:0060314 9.63 CALM1 CALM3
19 regulation of cardiac muscle contraction GO:0055117 9.63 CALM1 CALM2 CALM3
20 dolichol-linked oligosaccharide biosynthetic process GO:0006488 9.62 ALG10 ALG10B
21 regulation of synaptic vesicle endocytosis GO:1900242 9.62 CALM1 CALM3
22 establishment of protein localization to membrane GO:0090150 9.61 CALM1 CALM3
23 negative regulation of peptidyl-threonine phosphorylation GO:0010801 9.61 CALM1 CALM2 CALM3
24 regulation of high voltage-gated calcium channel activity GO:1901841 9.6 CALM1 CALM3
25 positive regulation of phosphoprotein phosphatase activity GO:0032516 9.58 CALM1 CALM2 CALM3
26 establishment of protein localization to mitochondrial membrane GO:0090151 9.55 CALM1 CALM3
27 detection of calcium ion GO:0005513 9.54 CALM1 CALM2 CALM3
28 negative regulation of ryanodine-sensitive calcium-release channel activity GO:0060315 9.5 CALM1 CALM2 CALM3
29 positive regulation of ryanodine-sensitive calcium-release channel activity GO:0060316 9.43 CALM1 CALM2 CALM3
30 regulation of cell communication by electrical coupling involved in cardiac conduction GO:1901844 9.33 CALM1 CALM2 CALM3
31 positive regulation of cyclic-nucleotide phosphodiesterase activity GO:0051343 9.13 CALM1 CALM2 CALM3
32 positive regulation by host of symbiont cAMP-mediated signal transduction GO:0075206 8.8 CALM1 CALM2 CALM3

Molecular functions related to Acute Dacryocystitis according to GeneCards Suite gene sharing:

(show all 17)
# Name GO ID Score Top Affiliating Genes
1 kinase activity GO:0016301 9.87 CALM1 CALM2 CALM3 TAOK3
2 ion channel binding GO:0044325 9.71 CALM1 CALM2 CALM3
3 disordered domain specific binding GO:0097718 9.63 CALM1 CALM2 CALM3
4 enzyme regulator activity GO:0030234 9.56 CALM1 CALM3
5 phosphatidylinositol 3-kinase binding GO:0043548 9.55 CALM1 CALM3
6 protein serine/threonine kinase activator activity GO:0043539 9.54 CALM1 CALM2 CALM3
7 nitric-oxide synthase binding GO:0050998 9.52 CALM1 CALM3
8 calcium channel inhibitor activity GO:0019855 9.51 CALM1 CALM2
9 titin binding GO:0031432 9.5 CALM1 CALM2 CALM3
10 nitric-oxide synthase regulator activity GO:0030235 9.49 CALM1 CALM3
11 dolichyl-phosphate-glucose-glycolipid alpha-glucosyltransferase activity GO:0004583 9.48 ALG10 ALG10B
12 dolichyl pyrophosphate Glc2Man9GlcNAc2 alpha-1,2-glucosyltransferase activity GO:0106073 9.43 ALG10 ALG10B
13 adenylate cyclase binding GO:0008179 9.43 CALM1 CALM2 CALM3
14 type 3 metabotropic glutamate receptor binding GO:0031800 9.4 CALM1 CALM3
15 protein phosphatase activator activity GO:0072542 9.33 CALM1 CALM2 CALM3
16 adenylate cyclase activator activity GO:0010856 9.13 CALM1 CALM2 CALM3
17 N-terminal myristoylation domain binding GO:0031997 8.8 CALM1 CALM2 CALM3

Sources for Acute Dacryocystitis

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
17 ExPASy
19 FMA
28 GO
29 GTR
30 HGMD
31 HMDB
32 HPO
33 ICD10
34 ICD10 via Orphanet
35 ICD9CM
36 IUPHAR
37 KEGG
38 LifeMap
40 LOVD
42 MedGen
44 MeSH
45 MESH via Orphanet
46 MGI
49 NCI
50 NCIt
51 NDF-RT
54 NINDS
55 Novoseek
57 OMIM
58 OMIM via Orphanet
62 PubMed
64 QIAGEN
69 SNOMED-CT via HPO
70 SNOMED-CT via Orphanet
71 TGDB
72 Tocris
73 UMLS
74 UMLS via Orphanet
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