MCID: ACT037
MIFTS: 36

Acute Dacryocystitis

Categories: Eye diseases

Aliases & Classifications for Acute Dacryocystitis

MalaCards integrated aliases for Acute Dacryocystitis:

Name: Acute Dacryocystitis 12 15 73
Dacryocystitis - Acute 12

Classifications:



External Ids:

Disease Ontology 12 DOID:12996
ICD10 33 H04.32
ICD9CM 35 375.32
SNOMED-CT 68 193986007 25470000
UMLS 73 C0155237

Summaries for Acute Dacryocystitis

MalaCards based summary : Acute Dacryocystitis, also known as dacryocystitis - acute, is related to sporotrichosis and dacryocystitis. An important gene associated with Acute Dacryocystitis is DCXR (Dicarbonyl And L-Xylulose Reductase), and among its related pathways/superpathways are Glycosaminoglycan metabolism and Glioma. The drug Calamus has been mentioned in the context of this disorder. Affiliated tissues include eye and b cells, and related phenotypes are Reduced mammosphere formation and Synthetic lethal with gemcitabine

Related Diseases for Acute Dacryocystitis

Diseases in the Dacryocystitis family:

Acute Dacryocystitis Chronic Dacryocystitis

Diseases related to Acute Dacryocystitis via text searches within MalaCards or GeneCards Suite gene sharing:

(show all 38)
# Related Disease Score Top Affiliating Genes
1 sporotrichosis 28.7 CALM1 CALM2 CALM3
2 dacryocystitis 10.6
3 lacrimal duct defect 10.0
4 lymphoma 9.9
5 orbital cellulitis 9.9
6 cellulitis 9.9
7 dacryocystocele 9.9
8 leukemia 9.7
9 sinusitis 9.7
10 keratoconjunctivitis sicca 9.7
11 oculoglandular tularemia 9.7
12 squamous cell carcinoma 9.7
13 tularemia 9.7
14 rhabdomyosarcoma 9.7
15 rhinitis 9.7
16 keratoconjunctivitis 9.7
17 fasciitis 9.7
18 necrotizing fasciitis 9.7
19 chronic dacryocystitis 9.7
20 external ear disease 9.4 CALM1 CALM2 CALM3
21 long qt syndrome 15 9.4 CALM1 CALM2 CALM3
22 otitis externa 9.4 CALM1 CALM2 CALM3
23 gestational choriocarcinoma 9.4 CALM1 CALM3
24 otomycosis 9.4 CALM1 CALM2 CALM3
25 spontaneous ocular nystagmus 9.4 CALM1 CALM2 CALM3
26 deafness, autosomal recessive 44 9.4 CALM1 CALM2 CALM3
27 dystonia 24 9.4 CALM1 CALM2 CALM3
28 triosephosphate isomerase deficiency 9.4 CALM1 CALM2 CALM3
29 leber congenital amaurosis 2 9.3 CALM1 CALM2 CALM3
30 primary systemic mycosis 9.3 CALM1 CALM2 CALM3
31 clear cell acanthoma 9.3 CALM1 CALM2 CALM3
32 cardiomyopathy, dilated, 1a 9.3 CALM1 CALM2 CALM3
33 cardiomyopathy, dilated, 1p 9.3 CALM1 CALM2 CALM3
34 deafness, autosomal dominant 2a 9.2 CALM1 CALM2 CALM3
35 primary cutaneous amyloidosis 9.2 CALM1 CALM2 CALM3
36 catecholaminergic polymorphic ventricular tachycardia 9.1 CALM1 CALM2 CALM3
37 long qt syndrome 1 9.0 CALM1 CALM2 CALM3
38 long qt syndrome 8.9 CALM1 CALM2 CALM3

Comorbidity relations with Acute Dacryocystitis via Phenotypic Disease Network (PDN):


Orbital Cellulitis

Graphical network of the top 20 diseases related to Acute Dacryocystitis:



Diseases related to Acute Dacryocystitis

Symptoms & Phenotypes for Acute Dacryocystitis

GenomeRNAi Phenotypes related to Acute Dacryocystitis according to GeneCards Suite gene sharing:

26
# Description GenomeRNAi Source Accession Score Top Affiliating Genes
1 Reduced mammosphere formation GR00396-S 9.26 CALM1 CALM2 CALM3 DCXR
2 Synthetic lethal with gemcitabine GR00225-A 8.62 CALM1 TAOK3

Drugs & Therapeutics for Acute Dacryocystitis

Drugs for Acute Dacryocystitis (from DrugBank, HMDB, Dgidb, PharmGKB, IUPHAR, NovoSeek, BitterDB):


# Name Status Phase Clinical Trials Cas Number PubChem Id
1 Calamus Nutraceutical Not Applicable

Interventional clinical trials:


# Name Status NCT ID Phase Drugs
1 The Microbiological Spectrum in Acute Dacryocystitis Completed NCT00349297
2 Endoscopy Assisted Probing Versus Simple Probing in Primary Congenital Nasolacrimal Duct Obstruction Recruiting NCT03242681 Not Applicable

Search NIH Clinical Center for Acute Dacryocystitis

Genetic Tests for Acute Dacryocystitis

Anatomical Context for Acute Dacryocystitis

MalaCards organs/tissues related to Acute Dacryocystitis:

41
Eye, B Cells

Publications for Acute Dacryocystitis

Articles related to Acute Dacryocystitis:

(show top 50) (show all 60)
# Title Authors Year
1
A Neonate With Acute Dacryocystitis. ( 28973285 )
2018
2
Odontogenic abscess mimicking acute dacryocystitis. ( 28455457 )
2017
3
Success Rate of Conventional Dacryocystorhinostomy in Post-acute Dacryocystitis Compared to Endonasal Dacryocystorhinostomy in Acute Dacryocystitis. ( 28791062 )
2017
4
Clinical Outcome of Probing in Infants with Acute Dacryocystitis - A Prospective Study. ( 28969168 )
2017
5
Primary vs Secondary Endoscopic Dacryocystorhinostomy for Acute Dacryocystitis With Lacrimal Sac Abscess Formation: A Randomized Clinical Trial. ( 29121183 )
2017
6
Primary Nonendoscopic Endonasal Versus Delayed External Dacryocystorhinostomy in Acute Dacryocystitis. ( 27505272 )
2016
7
Complete Vision Loss following Orbital Cellulitis Secondary to Acute Dacryocystitis. ( 27803829 )
2016
8
Microbiology of primary acquired nasolacrimal duct obstruction: simple epiphora, acute dacryocystitis, and chronic dacryocystitis. ( 26955261 )
2016
9
Pediatric Acute Dacryocystitis. ( 25856337 )
2015
10
Acute dacryocystitis as a presenting sign of chronic lymphocytic leukaemia. ( 26183368 )
2015
11
Long-term outcomes of powered endoscopic dacryocystorhinostomy in acute dacryocystitis. ( 25994372 )
2015
12
Acute dacryocystitis: another clinical manifestation of sporotrichosis. ( 24810176 )
2014
13
Primary Powered Endoscopic Dacryocystorhinostomy in the Setting of Acute Dacryocystitis and Lacrimal Abscess. ( 25226100 )
2014
14
Dacryolith-induced acute dacryocystitis: a reversible cause of nasolacrimal duct obstruction. ( 24568662 )
2014
15
Acute Dacryocystitis with Empyema of the Lacrimal Sac: Is Immediate Endoscopic Dacryocystorhinostomy Justified? ( 24647640 )
2014
16
Cardiobacterium hominis -induced acute dacryocystitis and lacrimal abscess. ( 24008805 )
2013
17
Unilateral acute dacryocystitis associated with oculoglandular tularemia: a case report. ( 23448564 )
2013
18
Clinical Profile and Management Outcome of Acute Dacryocystitis: Two Decades of Experience in a Tertiary Eye Care Center. ( 24171807 )
2013
19
Acute dacryocystitis in a 2-year old child caused by pantoea. ( 22296230 )
2012
20
Community-acquired methicillin-resistant Staphylococcus aureus bilateral acute dacryocystitis in a neonate. ( 22446919 )
2012
21
Endoscopic dacryocystorhinostomy in acute dacryocystitis: a multicenter case series. ( 21281068 )
2011
22
Acute dacryocystitis associated with epstein-barr virus infection. ( 21957956 )
2011
23
Enlarging red swelling below the right eye. What's your diagnosis? Diagnosis: Congenital dacryocystocele with acute dacryocystitis. ( 20349896 )
2010
24
An uncommon complication of septorhinoplasty, acute dacryocystitis. ( 19756855 )
2010
25
Primary treatment of acute dacryocystitis by endoscopic dacryocystorhinostomy with silicone intubation guided by a soft probe. ( 19118702 )
2009
26
Acute dacryocystitis causing orbital cellulitis and abscess. ( 19839913 )
2009
27
Congenital lacrimal system anomalies mimicking recurrent acute dacryocystitis. ( 18209645 )
2008
28
Primary endoscopic dacryocystorhinostomy as treatment for acute dacryocystitis with abscess formation. ( 18439951 )
2008
29
Orbital abscess secondary to acute dacryocystitis: case report. ( 18797671 )
2008
30
A silastic sheet found during endoscopic transnasal dacryocystorhinostomy for acute dacryocystitis. ( 16768193 )
2006
31
Congenital dacryocystocele with acute dacryocystitis: report of two cases. ( 17016968 )
2006
32
Rhabdomyosarcoma masquerading as acute dacryocystitis. ( 16304528 )
2005
33
Squamous cell carcinoma of the frontal and ethmoidal paranasal sinuses masquerading as acute dacryocystitis. ( 14765102 )
2004
34
The treatment of acute dacryocystitis using laser assisted endonasal dacryocystorhinostomy. ( 14693791 )
2004
35
Primary lacrimal sac B-cell immunoblastic lymphoma simulating an acute dacryocystitis. ( 12868025 )
2003
36
Facial necrotizing fasciitis following acute dacryocystitis. ( 12834700 )
2003
37
Acute dacryocystitis presenting as an orbital abscess. ( 11885795 )
2002
38
Endonasal dacryocystorhinostomy in the primary treatment of acute dacryocystitis with abscess formation. ( 11388383 )
2001
39
Acute dacryocystitis as a presenting sign of pediatric leukemia. ( 10372893 )
1999
40
An orbital abscess secondary to acute dacryocystitis. ( 9304639 )
1997
41
Orbital abscess secondary to acute dacryocystitis. ( 8804761 )
1996
42
Acute dacryocystitis: an unusual cause of life-threatening orbital intraconal abscess with frozen globe. ( 8944391 )
1996
43
Nasolacrimal duct obstruction and acute dacryocystitis associated with infectious mononucleosis (Epstein-Barr virus) ( 8381586 )
1993
44
Acute dacryocystitis secondary to exudative rhinitis. ( 8382941 )
1993
45
Management of acute dacryocystitis in adults. ( 8443113 )
1993
46
Orbital abscess due to acute dacryocystitis. ( 8343918 )
1993
47
Acute dacryocystitis resembling an infected subcutaneous cystic tumor. ( 1806606 )
1991
48
Acute dacryocystitis after punctal occlusion of keratoconjunctivitis sicca. ( 2039051 )
1991
49
Treatment of acute dacryocystitis in neonates. ( 1757861 )
1991
50
Combined anaerobic and coliform infection in acute dacryocystitis. ( 1955969 )
1991

Variations for Acute Dacryocystitis

Expression for Acute Dacryocystitis

Search GEO for disease gene expression data for Acute Dacryocystitis.

Pathways for Acute Dacryocystitis

Pathways related to Acute Dacryocystitis according to GeneCards Suite gene sharing:

(show top 50) (show all 90)
# Super pathways Score Top Affiliating Genes
1
Show member pathways
12.72 CALM1 CALM2 CALM3 DCXR
2
Show member pathways
12.61 CALM1 CALM2 CALM3
3
Show member pathways
12.58 CALM1 CALM2 CALM3
4
Show member pathways
12.58 CALM1 CALM2 CALM3
5
Show member pathways
12.58 CALM1 CALM2 CALM3
6
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12.57 CALM1 CALM2 CALM3
7
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12.56 CALM1 CALM2 CALM3
8
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12.53 CALM1 CALM2 CALM3
9
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12.52 CALM1 CALM2 CALM3
10
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12.52 CALM1 CALM2 CALM3
11
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12.51 CALM1 CALM2 CALM3
12
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12.47 CALM1 CALM2 CALM3
13
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12.46 CALM1 CALM2 CALM3
14
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12.45 CALM1 CALM2 CALM3
15
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12.45 CALM1 CALM2 CALM3
16
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12.43 CALM1 CALM2 CALM3
17
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12.42 CALM1 CALM2 CALM3
18
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12.41 CALM1 CALM2 CALM3
19
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12.4 CALM1 CALM2 CALM3
20
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12.38 CALM1 CALM2 CALM3
21
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12.33 CALM1 CALM2 CALM3
22
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12.32 CALM1 CALM2 CALM3
23
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12.31 CALM1 CALM2 CALM3
24
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12.31 CALM1 CALM2 CALM3
25
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12.29 CALM1 CALM2 CALM3
26
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12.28 CALM1 CALM2 CALM3
27
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12.27 CALM1 CALM2 CALM3
28 12.26 CALM1 CALM2 CALM3
29
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12.25 CALM1 CALM2 CALM3
30
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12.24 CALM1 CALM2 CALM3
31
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12.22 CALM1 CALM2 CALM3
32
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12.22 CALM1 CALM2 CALM3
33
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12.21 CALM1 CALM2 CALM3
34
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12.19 CALM1 CALM2 CALM3
35
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12.16 CALM1 CALM2 CALM3
36
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12.16 CALM1 CALM2 CALM3
37
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12.15 CALM1 CALM2 CALM3
38
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12.14 CALM1 CALM2 CALM3
39 12.12 CALM1 CALM2 CALM3
40
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12.11 CALM1 CALM2 CALM3
41
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12.1 CALM1 CALM2 CALM3
42
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12.08 CALM1 CALM2 CALM3
43
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12.08 CALM1 CALM2 CALM3
44
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12.06 CALM1 CALM2 CALM3
45 12.06 CALM1 CALM2 CALM3
46
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12.04 CALM1 CALM2 CALM3
47
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12.02 CALM1 CALM2 CALM3
48 11.98 CALM1 CALM2 CALM3
49 11.98 CALM1 CALM2 CALM3
50
Show member pathways
11.94 CALM1 CALM2 CALM3

GO Terms for Acute Dacryocystitis

Cellular components related to Acute Dacryocystitis according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 plasma membrane GO:0005886 9.91 CALM1 CALM2 CALM3 CPLX3 DCXR DEGS1
2 spindle GO:0005819 9.61 CALM1 CALM2 CALM3
3 vesicle GO:0031982 9.58 CALM1 CALM2 CALM3
4 spindle pole GO:0000922 9.5 CALM1 CALM2 CALM3
5 sarcomere GO:0030017 9.43 CALM1 CALM2 CALM3
6 spindle microtubule GO:0005876 9.33 CALM1 CALM2 CALM3
7 calcium channel complex GO:0034704 9.13 CALM1 CALM2 CALM3
8 catalytic complex GO:1902494 8.8 CALM1 CALM2 CALM3

Biological processes related to Acute Dacryocystitis according to GeneCards Suite gene sharing:

(show all 21)
# Name GO ID Score Top Affiliating Genes
1 phosphorylation GO:0016310 9.9 CALM1 CALM2 CALM3 TAOK3
2 response to calcium ion GO:0051592 9.77 CALM1 CALM2 CALM3
3 positive regulation of protein serine/threonine kinase activity GO:0071902 9.76 CALM1 CALM2 CALM3
4 substantia nigra development GO:0021762 9.75 CALM1 CALM2 CALM3
5 regulation of cytokinesis GO:0032465 9.74 CALM1 CALM2 CALM3
6 regulation of heart rate GO:0002027 9.73 CALM1 CALM2 CALM3
7 positive regulation of peptidyl-threonine phosphorylation GO:0010800 9.72 CALM1 CALM2 CALM3
8 positive regulation of protein autophosphorylation GO:0031954 9.71 CALM1 CALM2 CALM3
9 positive regulation of protein dephosphorylation GO:0035307 9.7 CALM1 CALM2 CALM3
10 regulation of cardiac muscle contraction by regulation of the release of sequestered calcium ion GO:0010881 9.69 CALM1 CALM2 CALM3
11 regulation of release of sequestered calcium ion into cytosol by sarcoplasmic reticulum GO:0010880 9.67 CALM1 CALM2 CALM3
12 regulation of cardiac muscle contraction GO:0055117 9.65 CALM1 CALM2 CALM3
13 positive regulation of phosphoprotein phosphatase activity GO:0032516 9.63 CALM1 CALM2 CALM3
14 negative regulation of peptidyl-threonine phosphorylation GO:0010801 9.61 CALM1 CALM2 CALM3
15 obsolete positive regulation of cAMP biosynthetic process GO:0030819 9.58 CALM1 CALM2 CALM3
16 detection of calcium ion GO:0005513 9.54 CALM1 CALM2 CALM3
17 negative regulation of ryanodine-sensitive calcium-release channel activity GO:0060315 9.5 CALM1 CALM2 CALM3
18 positive regulation of ryanodine-sensitive calcium-release channel activity GO:0060316 9.43 CALM1 CALM2 CALM3
19 regulation of cell communication by electrical coupling involved in cardiac conduction GO:1901844 9.33 CALM1 CALM2 CALM3
20 positive regulation of cyclic-nucleotide phosphodiesterase activity GO:0051343 9.13 CALM1 CALM2 CALM3
21 positive regulation of cyclic nucleotide metabolic process GO:0030801 8.8 CALM1 CALM2 CALM3

Molecular functions related to Acute Dacryocystitis according to GeneCards Suite gene sharing:

(show all 11)
# Name GO ID Score Top Affiliating Genes
1 kinase activity GO:0016301 9.76 CALM1 CALM2 CALM3 TAOK3
2 protein kinase binding GO:0019901 9.67 CALM1 CALM2 CALM3
3 protein domain specific binding GO:0019904 9.65 CALM1 CALM2 CALM3
4 ion channel binding GO:0044325 9.58 CALM1 CALM2 CALM3
5 disordered domain specific binding GO:0097718 9.54 CALM1 CALM2 CALM3
6 protein serine/threonine kinase activator activity GO:0043539 9.5 CALM1 CALM2 CALM3
7 calcium channel inhibitor activity GO:0019855 9.43 CALM1 CALM2
8 titin binding GO:0031432 9.43 CALM1 CALM2 CALM3
9 adenylate cyclase binding GO:0008179 9.33 CALM1 CALM2 CALM3
10 protein phosphatase activator activity GO:0072542 9.13 CALM1 CALM2 CALM3
11 N-terminal myristoylation domain binding GO:0031997 8.8 CALM1 CALM2 CALM3

Sources for Acute Dacryocystitis

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
17 ExPASy
19 FMA
28 GO
29 GTR
30 HGMD
31 HMDB
32 HPO
33 ICD10
34 ICD10 via Orphanet
35 ICD9CM
36 IUPHAR
37 KEGG
38 LifeMap
40 LOVD
42 MedGen
44 MeSH
45 MESH via Orphanet
46 MGI
49 NCI
50 NCIt
51 NDF-RT
54 NINDS
55 Novoseek
57 OMIM
58 OMIM via Orphanet
62 PubMed
64 QIAGEN
69 SNOMED-CT via HPO
70 SNOMED-CT via Orphanet
71 TGDB
72 Tocris
73 UMLS
74 UMLS via Orphanet
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