Acute Diarrhea

Categories: Gastrointestinal diseases, Genetic diseases, Infectious diseases, Nephrological diseases, Oral diseases, Rare diseases

Aliases & Classifications for Acute Diarrhea

MalaCards integrated aliases for Acute Diarrhea:

Name: Acute Diarrhea 12 15 70


External Ids:

Disease Ontology 12 DOID:0050140
UMLS 70 C0740441

Summaries for Acute Diarrhea

Disease Ontology : 12 A diarrhea that is of rapid onset and course characterized by frequent loose or liquid bowel movements. Acute diarrhea is a common cause of death in developing countries and the second most common cause of infant deaths worldwide.

MalaCards based summary : Acute Diarrhea is related to dysentery and inflammatory diarrhea, and has symptoms including diarrhea An important gene associated with Acute Diarrhea is MME (Membrane Metalloendopeptidase), and among its related pathways/superpathways is Glycosphingolipid biosynthesis - lacto and neolacto series. The drugs Loperamide and Benzocaine have been mentioned in the context of this disorder. Affiliated tissues include colon, kidney and small intestine, and related phenotypes are Decreased viability and Decreased viability

Wikipedia : 73 Gastroenteritis, also known as infectious diarrhea and gastro, is inflammation of the gastrointestinal... more...

Related Diseases for Acute Diarrhea

Diseases in the Diarrhea family:

Diarrhea 6 Diarrhea 9
Chronic Diarrhea Due to Guanylate Cyclase 2c Overactivity Inflammatory Diarrhea
Acute Diarrhea Congenital Diarrhea

Diseases related to Acute Diarrhea via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50) (show all 114)
# Related Disease Score Top Affiliating Genes
1 dysentery 30.0 STX2 STX1A ST8SIA2 SLC9A3 PRSS57
2 inflammatory diarrhea 29.7 SLC9A3R2 SLC9A3 PITX1
3 osmotic diarrhea 29.5 SLC9A3 PRSS57
4 secretory diarrhea 29.1 SLC9A3R2 SLC9A3 PRSS57
5 diarrhea 11.6
6 gastroenteritis 10.7
7 cholera 10.4
8 shigellosis 10.3
9 salmonellosis 10.3
10 metabolic acidosis 10.2
11 cryptosporidiosis 10.2
12 pouchitis 10.2 S100A9 LTF
13 hypokalemia 10.2
14 lactose intolerance 10.2
15 bacterial infectious disease 10.1
16 clostridium difficile colitis 10.1
17 constipation 10.1
18 47,xyy 10.1
19 cataract 18 10.1 SH2D3A S100A9
20 osteogenesis imperfecta, type vii 10.0 STX2 ST8SIA2
21 deficiency anemia 10.0
22 iron deficiency anemia 10.0
23 campylobacteriosis 10.0
24 pharyngitis 10.0
25 iron metabolism disease 10.0
26 severe acute respiratory syndrome 10.0
27 poliomyelitis 10.0
28 48,xyyy 10.0
29 tenosynovitis 10.0 SH2D3A PRSS57
30 western equine encephalitis 9.9 SH2D3A PRSS57
31 enterocolitis 9.9
32 dermatitis, atopic 9.9
33 disease by infectious agent 9.9
34 inflammatory bowel disease 9.9
35 neutropenia 9.9
36 rectum cancer 9.9
37 acute kidney failure 9.9
38 food allergy 9.9
39 plague 9.9
40 ileus 9.9
41 influenza 9.9
42 amebiasis 9.9
43 eastern equine encephalitis 9.8 SH2D3A PRSS57
44 blue toe syndrome 9.8 SPECC1 SH2D3A
45 ige responsiveness, atopic 9.8
46 kabuki syndrome 1 9.8
47 multinucleated neurons, anhydramnios, renal dysplasia, cerebellar hypoplasia, and hydranencephaly 9.8
48 immune deficiency disease 9.8
49 suppressor of tumorigenicity 11 9.8
50 homocysteinemia 9.8

Graphical network of the top 20 diseases related to Acute Diarrhea:

Diseases related to Acute Diarrhea

Symptoms & Phenotypes for Acute Diarrhea

UMLS symptoms related to Acute Diarrhea:


GenomeRNAi Phenotypes related to Acute Diarrhea according to GeneCards Suite gene sharing:

26 (show all 12)
# Description GenomeRNAi Source Accession Score Top Affiliating Genes
1 Decreased viability GR00221-A-1 9.62 PKM
2 Decreased viability GR00221-A-4 9.62 PKM
3 Decreased viability GR00231-A 9.62 PKM
4 Decreased viability GR00240-S-1 9.62 ST8SIA2
5 Decreased viability GR00249-S 9.62 FUT2 LTF ST8SIA2
6 Decreased viability GR00342-S-1 9.62 PKM
7 Decreased viability GR00342-S-2 9.62 PKM
8 Decreased viability GR00342-S-3 9.62 PKM
9 Decreased viability GR00381-A-1 9.62 LTF
10 Decreased viability GR00381-A-3 9.62 LTF
11 Decreased viability GR00386-A-1 9.62 RNF112 SLC9A3 STX1A STX2
12 Decreased viability GR00402-S-2 9.62 LTF PITX1 PKM SLC9A3R2

Drugs & Therapeutics for Acute Diarrhea

Drugs for Acute Diarrhea (from DrugBank, HMDB, Dgidb, PharmGKB, IUPHAR, NovoSeek, BitterDB):

(show all 45)
# Name Status Phase Clinical Trials Cas Number PubChem Id
Loperamide Approved Phase 4 53179-11-6 3955
Benzocaine Approved, Investigational Phase 4 1994-09-7, 94-09-7 2337
tannic acid Approved Phase 4 1401-55-4
Zinc Approved, Investigational Phase 4 7440-66-6 32051
Zinc sulfate Approved, Investigational Phase 4 7733-02-0
Simethicone Approved Phase 4 8050-81-5
Glycine Approved, Nutraceutical, Vet_approved Phase 4 56-40-6 750
8 Gastrointestinal Agents Phase 4
9 Antidiarrheals Phase 4
10 Acidophilus Phase 4
11 Trace Elements Phase 4
12 Nutrients Phase 4
13 Micronutrients Phase 4
14 Dermatologic Agents Phase 4
15 Emollients Phase 4
16 Chelating Agents Phase 4
Sulfasalazine Approved Phase 3 599-79-1 5353980 5359476
Octreotide Approved, Investigational Phase 3 83150-76-9 383414 6400441
Racecadotril Investigational Phase 3 81110-73-8
20 Anti-Infective Agents Phase 3
21 Antirheumatic Agents Phase 3
22 Anti-Inflammatory Agents Phase 3
23 Anti-Inflammatory Agents, Non-Steroidal Phase 3
24 Analgesics Phase 3
25 Analgesics, Non-Narcotic Phase 3
26 Antineoplastic Agents, Hormonal Phase 3
27 glutamine Phase 3
28 Pharmaceutical Solutions Phase 3
29 HIV Protease Inhibitors Phase 3
protease inhibitors Phase 3
Silicon Approved, Investigational Phase 2 7440-21-3 4082203
32 Locust bean gum Phase 1, Phase 2
Calcium carbonate Approved, Investigational 471-34-1
34 Bentonite Approved
35 Strawberry Approved
Lactoferrin Investigational 151186-19-5
37 Hormones
38 Antacids
39 Anti-Ulcer Agents
40 Calcium, Dietary
41 Sulfalene
42 Bifidobacterium
43 Anti-Bacterial Agents
44 Antibiotics, Antitubercular
Calcium Nutraceutical 7440-70-2 271

Interventional clinical trials:

(show all 41)
# Name Status NCT ID Phase Drugs
1 Efficacy of Racecadotril in the Management of Acute Watery Diarrhea in Children Completed NCT01577043 Phase 4 Racecadotril
2 Use of Probiotic Yogurt in the Treatment of Acute Diarrhea in Children: A Randomized Double-blind Trial Completed NCT01564290 Phase 4 Placebo probiotic
3 Oral Administration of Tannins and Flavonoids in Children With Acute Diarrhea : A Pilot, Randomized, Control-case Study Completed NCT03356327 Phase 4 Actitan F;Standard Oral Rehydration
4 The Effect of a Probiotic and/or Prebiotic on the Duration of Diarrhea and Length of Hospital Stay in Children With Acute Diarrhea: Prospective, Double Blind, Randomized Controlled Trial Completed NCT01927094 Phase 4
5 Efficacy of Use of Zinc in the Treatment of Acute Diarrhea in Infants Under Six Months. Completed NCT01571856 Phase 4 Zinc Sulfate
6 A Randomized, Parallel Group Comparison of Loperamide/Simeticone Caplet, Loperamide/Simeticone Chewable Tablet (IMODIUM® PLUS) and a Probiotic (Saccharomyces Boulardii) in the Treatment of Acute Diarrhea in Adults Completed NCT00807326 Phase 4 Loperamide/simeticone 2 mg/125 mg caplets;Loperamide/simeticone 2 mg/125 mg chewable tablets;Probiotic Saccharomyces boulardii 250 mg capsules
7 Effect of Zinc Sulphate and Zinc Amino Acid Chelate in Prevention Acute Diarrhea and Acute Respiratory Infection, Medellín 2012 Completed NCT01791608 Phase 4
8 Efficacy, Safety and Cost-effectiveness Analysis of Impact of Racecadotril as an Adjunct in the Treatment of Acute Diarrhea in Mexican Children Completed NCT01153854 Phase 3 Racecadotril;Placebo groups
9 Multicenter, Open-label, Controlled, Randomized Clinical Study to Evaluate the Efficacy and Safety of Racecadotril in Infants, Children and Adolescents With Acute Diarrhea Completed NCT03463512 Phase 3 Racecadotril plus ORS;ORS
10 Efficacy of a New Hypotonic Oral Rehydration Solution Containing Zinc and Prebiotics in the Treatment of Children With Acute Diarrhea Completed NCT01025583 Phase 2, Phase 3
11 Phase III, Randomized, Study of Sulfasalazine Versus Placebo in the Prevention of Acute Diarrhea in Patients Receiving Pelvic Radiation Therapy Completed NCT01198145 Phase 3 sulfasalazine
12 Clinical Effectiveness and Preventive Impact of Home Zinc Treatment for Acute Diarrhea in Children: A Cluster-randomized Field Trial in Rural Western Kenya Completed NCT00530829 Phase 3 zinc
13 A Multi-center, Randomized, Double-blind, Double-dummy, and Parallel Controlled Phase 3 Study to Evaluate the Efficacy and Safety of Loperamide Hydrochloride/Simethicone Chewable Tablet in the Treatment of Acute Diarrhea With Abdominal Discomfort and Flatulence Completed NCT02340481 Phase 3 Loperamide hydrochloride + simethicone chewable tablet;Loperamide hydrochloride;Loperamide hydrochloride + simethicone chewable placebo tablet;Loperamide hydrochloride placebo capsule
14 Phase III Comparative Study to Assess the Efficacy and Safety of Oral Rehydration Therapy (ORT) in Combination With Spores of Bacillus Clausii (Enterogermina)Versus ORT Alone, Administered for 5 Days With the Treatment of Acute Diarrhea in Children. Completed NCT00457353 Phase 3 Bacillus Clausii
15 Phase III Double-Blind Study Of Depot Octreotide Versus Placebo In The Prevention Of Acute Diarrhea In Patients Receiving Pelvic Radiation Therapy Completed NCT00033605 Phase 3 octreotide acetate
16 Phase III Double-Blind Study of Glutamine Versus Placebo in the Prevention of Acute Diarrhea in Patients Receiving Pelvic Radiation Therapy Completed NCT00003170 Phase 3
17 Extended Studies on Safety and Efficacy of Zinc-ORS Compared to ORS Alone in Hospitalized Children With Severe and Complicated Acute Diarrhea Completed NCT00370968 Phase 2, Phase 3 Zinc sulphate
18 Efficacy and Safety of Racecadotril in the Treatment of Children Aged 3 to 60 Months Suffering From Acute Diarrhea: An Open-label Study Recruiting NCT03473561 Phase 3 Racecadotril plus ORS
19 Effectiveness and Efficacy of Zinc With Probiotics for the Treatment of Acute Diarrhea in Young Children Unknown status NCT01140074 Phase 2 Zinc Sulfate
20 Influence of Carob and Probiotics on Acute Diarrhea in Children Unknown status NCT01501305 Phase 1, Phase 2
21 Study of Nutritional Regime for Acute Diarrhea Completed NCT01269892 Phase 2
22 Efficacy of the Administration of Colloidal Silicon Dioxide in Tablet Dosage Form (Carbowhite) in Patients With Acute Diarrhea. Completed NCT03633344 Phase 2 Carbowhite;Carbowhite placebo
23 Cost-effectiveness of Infloran (TM) in Treating Acute Childhood Diarrhea in Phramongkutklao Hospital Unknown status NCT01273012 Probiotic - Infloran
24 Calcium, Probiotics and Acute Diarrheal Disease Among Indonesian Children Aged 1-6 Years in Low Socio-economic Urban Area of East Jakarta Completed NCT00512824
25 Probiotics in the Management of Acute Rotavirus Diarrhea in Bolivian Children: Randomized Double-blind, Controlled Trial Using Two Different Preparations Completed NCT00981877 GB (Florestor);GRALB;GC (placebo)
26 Chinese Pediatric Massage on Children With Acute Diarrhea: a Randomized Sham Massage Controlled Trial Completed NCT03005821
27 Comparing the Efficacy of Different Zinc Formulations in the Treatment of Acute Diarrhea Among Young Children at Hospital Based Setting in Pakistan Completed NCT00682955 Zinc Sulphate;Zinc Sulphate
28 Treatment of Acute Childhood Diarrhoea With Human Milk Oligosaccharides and Impact on Gut Micro Biota Dysbiosis and Nutritional Status Completed NCT02896465
29 Comparative Evaluation of Accuracy of Fecal Calprotectin, Lactoferrin and Occult Blood Testing (FOBT) in Predicting Microbiological Diagnosis for Acute Infectious Diarrhea: A Prospective Multicentre Double Blind Randomized Controlled Trial. Completed NCT00429325
30 Comparison Of Outcome Of Lactose Free Formula Milk With Yogurt In Children With Acute Diarrhea Completed NCT04796480
31 A Double-blind, Randomized, Placebo-controlled Clinical Trial (Pilot Phase) to Evaluate the Efficacy of a Medical Nutrition Product, PTM202, in Children With Acute Diarrhea Completed NCT01814202
32 Zinc Sulfate Acceptability Study in Children With Acute Diarrhea: A Prospective, Open-label, Interventional Study Completed NCT04039828 Zinc Sulfate Dispersible Tablet 20 mg (Elemental Zinc 20 mg as Zinc Sulfate Monohydrate / Tablet)
33 Study on Oral Administration of Bifidobacterium Longum BB536 on Incidence of Acute Diarrhea and/or Respiratory- Related Illnesses Compared to Placebo Completed NCT02434042
34 A Double Blind Randomized Placebo Controlled Trial of Oral Zinc for Children With Acute Diarrhea in a Developed Nation. Completed NCT01198587 Zinc Sulfate;Placebo oral capsule
35 Two Year (2009-2010) Surveillance of Rotavirus Genotypes Causing Acute Diarrhea in Children Younger Than 5 Years of Age Requiring Emergency Room and Hospital Admission in Two Large Cities in Chile. Completed NCT00895492
36 Establishing the Optimal Dose of Therapeutic Zinc Supplementation for the Treatment of Acute Diarrhea in Under Five Children - a Dose Response Trial in a South Asian and a Sub-Saharan African Setting Completed NCT03078842
37 Results of FilmArray® Gastro-intestinal Panel (GI Panel) and Serum Procalcitonin (PCT) in Acute Colitis and Infectious Diarrhea in the Emergency Department. Recruiting NCT04237181
38 The Efficacy Of Probiotics Versus Zinc Versus Probiotics-Zinc Combination On Acute Diarrhea In Children: A Double Blind Clinical Trial Recruiting NCT03684538
39 Novel Approach to Improve Patient Care and Diarrheal Disease Research Using Mobile Technology Active, not recruiting NCT03943654
40 Probiotics Oral Administration Attenuate Postoperative Cognition Decline in Elderly Orthopedic Patients Not yet recruiting NCT04017403 Bifidobacterium triple live capsule;Placebos
41 Probiotics in the Prevention of Antibiotic-Associated Diarrhea in Hospitalized Children: a Randomized Trial Terminated NCT02817165

Search NIH Clinical Center for Acute Diarrhea

Genetic Tests for Acute Diarrhea

Anatomical Context for Acute Diarrhea

MalaCards organs/tissues related to Acute Diarrhea:

Colon, Kidney, Small Intestine, Pancreas, Liver, Heart, Breast

Publications for Acute Diarrhea

Articles related to Acute Diarrhea:

(show top 50) (show all 2862)
# Title Authors PMID Year
A potential system for the isolation and propagation of porcine deltacoronavirus using embryonated chicken eggs. 61
33460683 2021
Molecular and Clinical Epidemiological Features of Human Astrovirus Infections in Children with Acute Gastroenteritis in Shandong province, China. 61
33811682 2021
Involvement and practice of community pharmacists in maternal and child health services: A systematic review. 61
32800713 2021
Epidemiology and Viral Etiology of Pediatric Immune Thrombocytopenia through Korean Public Health Data Analysis. 61
33806145 2021
Priorities for intervention to prevent diarrhea among children aged 0-23 months in northeastern Ethiopia: a matched case-control study. 61
33789606 2021
Diarrhea in an infant due to Shigella flexneri 1 carrying multiple cephalosporinase-encoding genes. 61
33743818 2021
Recombination Lactococcus lactis expressing Helicobacter pylori neutrophil-activating protein A attenuates food allergy symptoms in mice. 61
33749737 2021
Porcine Coronaviruses: Overview of the State of the Art. 61
33723809 2021
Rotavirus Diarrhea and its Determinants Among Under-Five Children Admitted in a Tertiary Care Hospital of Southern Haryana, India. 61
33501607 2021
Post Vaccination Epidemiology and Genotyping of Rotavirus Gastroenteritis at a Tertiary Care Centre of North-East Rajasthan. 61
33247377 2021
Rotavirus Diarrhea in Hospitalized Under-5 Children in Madhya Pradesh, India and the Prevalent Serotypes After Vaccine Introduction. 61
33415553 2021
Prevalence, Virulence Gene Profiling and Characterization of Enteroaggregative Escherichia coli From Acute Diarrhea, Asymptomatic Nourished and Malnourished Children Less Than 5 Years of Age in India. 61
33713662 2021
Derivation of the first clinical diagnostic models for dehydration severity in patients over five years with acute diarrhea. 61
33690646 2021
Randomized, placebo-controlled trial of xyloglucan and gelose for the treatment of acute diarrhea in children. 61
33028102 2021
Things We Do for No Reason™: Ova and Parasite Testing in Patients With Acute Diarrhea Arising During Hospitalization. 61
33734981 2021
Management of Chronic Diarrhea in Primary Care: The Gastroenterologists Advice. 61
33588424 2021
Review of zoonotic amebiasis: Epidemiology, clinical signs, diagnosis, treatment, prevention and control. 61
33676155 2021
Human bocavirus genotypes 1, 2, and 3 circulating in pediatric patients with acute gastroenteritis in Chiang Mai, Thailand, 2012-2018. 61
33486373 2021
A case of successful treatment of severe COVID-19 pneumonia with favipiravir and tocilizumab in post-kidney transplant recipient. 61
32585765 2021
Extensive recombination-driven coronavirus diversification expands the pool of potential pandemic pathogens. 61
33564759 2021
Antibiotic stewardship in direct-to-consumer telemedicine consultations leads to high adherence to best practice guidelines and a low prescription rate. 61
33578013 2021
Rotavirus vaccine effectiveness and impact in Uzbekistan, the first country to introduce in central Asia. 61
32755429 2021
Etiological profile of diarrhea in solid organ transplant recipients at a tertiary care center in Southern India. 61
33594745 2021
Acute diarrhea-induced shock during alcohol withdrawal: a case study. 61
33626960 2021
Plasmid-borne colistin resistance gene mcr-1 in a multidrug resistant Salmonella enterica serovar Typhimurium isolate from an infant with acute diarrhea in China. 61
33212253 2021
[TAFRO syndrome and cutaneous necrotizing vasculitis]. 61
33218790 2021
An investigation of the potential association between gastrointestinal viral and bacterial infection and development of intestinal acute graft versus host disease following allogeneic hematopoietic stem cell transplantation. 61
33605457 2021
Emergence of Bat-Related Betacoronaviruses: Hazard and Risks. 61
33790874 2021
Effects of a national policy advocating rational drug use on decreases in outpatient antibiotic prescribing rates in Thailand. 61
33628347 2021
Molecular detection and characterization of norovirus in asymptomatic food handlers in Chiang Mai, Thailand. 61
33465494 2021
Prevalence of Escherichia coli O157:H7 and associated factors in under-five children in Eastern Ethiopia. 61
33508023 2021
A Simulated Client Exploration of Nonprescription Dispensing of Antibiotics at Drugstores for Pediatric Acute Diarrhea and Upper Respiratory Infection in Lahore, Pakistan. 61
33790584 2021
Chinese pediatric Tuina on children with acute diarrhea: a randomized sham-controlled trial. 61
33407547 2021
Swine Acute Diarrhea Syndrome Coronavirus Nucleocapsid Protein Antagonizes Interferon-β Production via Blocking the Interaction Between TRAF3 and TBK1. 61
33692778 2021
Frequency of five Escherichia Coli pathotypes in Iranian adults and children with acute diarrhea. 61
33539359 2021
Rectal Dose Is the Other Dosimetric Factor in Addition to Small Bowel for Prediction of Acute Diarrhea during Postoperative Whole-Pelvic Intensity-Modulated Radiotherapy in Gynecologic Patients. 61
33525461 2021
Morbidity Among Athletes Presenting for Medical Care During 3 Iterations of an Ultratrail Race in the Himalayas. 61
33168403 2020
Molecular Epidemiology of Enteroaggregative Escherichia coli (EAEC) Isolates of Hospitalized Children from Bolivia Reveal High Heterogeneity and Multidrug-Resistance. 61
33334000 2020
Prevalence and Correlates of Cryptosporidium Infections in Kenyan Children With Diarrhea and Their Primary Caregivers. 61
33335937 2020
Porcine epidemic diarrhea virus: Molecular mechanisms of attenuation and vaccines. 61
33011361 2020
The Use of Activated Micronized Zeolite Clinoptilolite as a Possible Alternative to Antibiotics and Chestnut Extract for the Control of Undifferentiated Calf Diarrhea: An In Vitro and In Vivo Study. 61
33287303 2020
FilmArray GI-panel performance for the rapid and multiple detection of gastrointestinal microorganisms in foodborne illness outbreaks in Shenzhen during 2018-2019. 61
33132110 2020
Serotypes, antibiotic resistance, and virulence genes of Salmonella in children with diarrhea. 61
32797660 2020
Epidemiology of rotavirus diarrhea among children less than 5 years hospitalized with acute gastroenteritis prior to rotavirus vaccine introduction in India. 61
33168345 2020
An interlaboratory study on the detection methods for enterotoxigenic Escherichia coli in vegetables using enterotoxin gene screening and selective agars for ETEC-specific isolation. 61
32823166 2020
The Prevalence of Shiga toxin-1 in non-Shigella dysenteriae isolates collected from diarrhea samples in patients, Ahvaz, Iran. 61
33292146 2020
Prevalence of Rotaviruses in the Etiology of Acute Diarrhea in Young Children, Clinical forms, Extraintestinal Manifestations and Complications. 61
33500370 2020
Diarrhea in Children with Plasmodium falciparum Malaria: A Case-Control Study on the Prevalence and Response to Antimalarial Treatment. 61
33319726 2020
Rare and Fatal Gastrointestinal Mucormycosis (Zygomycosis) in a COVID-19 Patient: A Case Report. 61
33207116 2020
Description of Enteropathic Escherichia coli Species in Pediatric Patients at a Quaternary Children's Hospital. 61
31803928 2020

Variations for Acute Diarrhea

Expression for Acute Diarrhea

Search GEO for disease gene expression data for Acute Diarrhea.

Pathways for Acute Diarrhea

Pathways related to Acute Diarrhea according to GeneCards Suite gene sharing:

# Super pathways Score Top Affiliating Genes
1 10.05 FUT3 FUT2

GO Terms for Acute Diarrhea

Cellular components related to Acute Diarrhea according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 extracellular exosome GO:0070062 9.76 SLC9A3R2 SLC9A3 S100A9 PKM MME LTF
2 presynaptic active zone membrane GO:0048787 8.96 STX2 STX1A
3 synaptic vesicle GO:0008021 8.92 STX2 STX1A RNF112 MME

Biological processes related to Acute Diarrhea according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 oligosaccharide metabolic process GO:0009311 9.37 ST8SIA2 FUT3
2 vesicle docking GO:0048278 9.32 STX2 STX1A
3 synaptic vesicle fusion to presynaptic active zone membrane GO:0031629 9.26 STX2 STX1A
4 fucosylation GO:0036065 9.16 FUT3 FUT2
5 response to gravity GO:0009629 8.96 STX1A PKM
6 myoblast fate commitment GO:0048625 8.62 PITX1 EPAS1

Molecular functions related to Acute Diarrhea according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 fucosyltransferase activity GO:0008417 8.96 FUT3 FUT2
2 calcium-dependent protein binding GO:0048306 8.8 STX2 STX1A S100A9

Sources for Acute Diarrhea

9 Cosmic
10 dbSNP
11 DGIdb
17 EFO
18 ExPASy
19 FMA
28 GO
29 GTR
31 HPO
32 ICD10
33 ICD10 via Orphanet
37 LifeMap
41 MedGen
44 MeSH
45 MESH via Orphanet
46 MGI
49 NCI
50 NCIt
54 Novoseek
56 OMIM via Orphanet
57 OMIM® (Updated 20-May-2021)
61 PubMed
69 Tocris
71 UMLS via Orphanet
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