MCID: ACT047
MIFTS: 29

Acute Endophthalmitis

Categories: Eye diseases, Neuronal diseases, Rare diseases

Aliases & Classifications for Acute Endophthalmitis

MalaCards integrated aliases for Acute Endophthalmitis:

Name: Acute Endophthalmitis 12 58 15 71

Characteristics:

Orphanet epidemiological data:

58
acute endophthalmitis
Inheritance: Not applicable; Age of onset: All ages; Age of death: normal life expectancy;

Classifications:

Orphanet: 58  
Rare eye diseases


External Ids:

Disease Ontology 12 DOID:11752
ICD9CM 34 360.01
SNOMED-CT 67 193268004
ICD10 via Orphanet 33 H44.0 H44.1
UMLS via Orphanet 72 C0154773
Orphanet 58 ORPHA279888
UMLS 71 C0154773

Summaries for Acute Endophthalmitis

MalaCards based summary : Acute Endophthalmitis is related to endophthalmitis and cataract. An important gene associated with Acute Endophthalmitis is AJM1 (Apical Junction Component 1 Homolog). The drugs Ethinyl Estradiol and Estradiol have been mentioned in the context of this disorder. Affiliated tissues include eye and endothelial.

Related Diseases for Acute Endophthalmitis

Diseases in the Endophthalmitis family:

Chronic Endophthalmitis Acute Endophthalmitis

Diseases related to Acute Endophthalmitis via text searches within MalaCards or GeneCards Suite gene sharing:

(show all 37)
# Related Disease Score Top Affiliating Genes
1 endophthalmitis 30.7 VEGFA PRF1
2 cataract 10.5
3 retinal detachment 10.2
4 hypopyon 10.2
5 macular degeneration, age-related, 1 10.1
6 vitreoretinopathy, neovascular inflammatory 10.0
7 vitreoretinopathy 10.0
8 pars planitis 10.0
9 leukemia, acute lymphoblastic 10.0
10 kuhnt-junius degeneration 10.0
11 retinal vein occlusion 10.0
12 macular retinal edema 10.0
13 retinal disease 10.0
14 microvascular complications of diabetes 5 9.8
15 aspergillosis 9.8
16 infective endocarditis 9.8
17 osteomyelitis 9.8
18 endocarditis 9.8
19 chronic endophthalmitis 9.8
20 corneal edema 9.8
21 acute leukemia 9.8
22 uveitis 9.8
23 panophthalmitis 9.8
24 iritis 9.8
25 papilledema 9.8
26 factitious disorder 9.8
27 aortitis 9.8
28 eye disease 9.8
29 corneal ulcer 9.8
30 vitreous abscess 9.8
31 48,xyyy 9.8
32 stenotrophomonas maltophilia infection 9.8
33 blood group, globoside system 9.7 VEGFA PRF1
34 endocardium disease 9.6 PRF1 PLGLB1
35 behcet syndrome 9.6 VEGFA PRF1
36 celiac disease 1 9.5 TOR1B PRF1
37 purulent endophthalmitis 9.2 VEGFA TOR1B PRF1 AJM1

Comorbidity relations with Acute Endophthalmitis via Phenotypic Disease Network (PDN):


Hypopyon Purulent Endophthalmitis

Graphical network of the top 20 diseases related to Acute Endophthalmitis:



Diseases related to Acute Endophthalmitis

Symptoms & Phenotypes for Acute Endophthalmitis

Drugs & Therapeutics for Acute Endophthalmitis

Drugs for Acute Endophthalmitis (from DrugBank, HMDB, Dgidb, PharmGKB, IUPHAR, NovoSeek, BitterDB):

(show all 21)
# Name Status Phase Clinical Trials Cas Number PubChem Id
1
Ethinyl Estradiol Approved Phase 3 57-63-6 5991
2
Estradiol Approved, Investigational, Vet_approved Phase 3 50-28-2 5757
3
Moxifloxacin Approved, Investigational Phase 3 151096-09-2, 354812-41-2 152946
4
Norgestimate Approved, Investigational Phase 3 35189-28-7 6540478
5
Polyestradiol phosphate Approved Phase 3 28014-46-2
6 Estradiol 3-benzoate Phase 3
7 Contraceptive Agents Phase 3
8 Contraceptives, Oral Phase 3
9 Contraceptives, Oral, Combined Phase 3
10 Anti-Infective Agents Phase 3
11 Anti-Bacterial Agents Phase 3
12 Norgestimate, ethinyl estradiol drug combination Phase 3
13 Estradiol 17 beta-cypionate Phase 3
14
Ceftazidime Approved 72558-82-8, 78439-06-2 5481173
15
Povidone-iodine Approved 25655-41-8
16
Iodine Approved, Investigational 7553-56-2 807
17
Vancomycin Approved 1404-90-6 441141 14969
18
Povidone Approved 9003-39-8 131751496
19
Cadexomer iodine Experimental 94820-09-4
20 Antibiotics, Antitubercular
21 Pharmaceutical Solutions

Interventional clinical trials:


# Name Status NCT ID Phase Drugs
1 Use of Intracameral Moxifloxacin for the Prevention of Acute Endophthalmitis Following Cataract Surgery: a Controlled and Randomized Clinical Trial Terminated NCT02770729 Phase 3 Moxifloxacin;No injection of moxifloxacin
2 Contribution of Fast Molecular Bacterial Identification by Real-time PCR in Managing of Postoperative Acute Endophthalmitis Unknown status NCT02850653
3 Evaluation do Early Pars Plana Vitrectomy in Acute Endophthalmitis Recruiting NCT04192994 Intravitreal Antibiotic Injection

Search NIH Clinical Center for Acute Endophthalmitis

Genetic Tests for Acute Endophthalmitis

Anatomical Context for Acute Endophthalmitis

MalaCards organs/tissues related to Acute Endophthalmitis:

40
Eye, Endothelial

Publications for Acute Endophthalmitis

Articles related to Acute Endophthalmitis:

(show top 50) (show all 198)
# Title Authors PMID Year
1
To implant or not to implant: emergency orbital eviscerations with primary orbital implants. 61
33432166 2021
2
Effectiveness of immediate vitrectomy and intravitreal antibiotics for post-injection endophthalmitis. 61
33502628 2021
3
Ten-year trends in the incidence, clinical profile and outcomes of acute-onset endophthalmitis following combined pars plana vitrectomy and sutureless, glueless and flapless scleral fixation of intraocular lenses. 61
33511515 2021
4
Brevibacterium casei endophthalmitis after intravitreal dexamethasone implant. 61
33281014 2020
5
Features and outcomes of eyes that underwent surgical repair of rhegmatogenous retinal detachments after being treated for acute endophthalmitis. 61
33394997 2020
6
Acute endophthalmitis after penetrating and endothelial keratoplasty at a tertiary eye care center over a 13-year period. 61
33120636 2020
7
Endophthalmitis Prophylaxis Study, Report 2: Intracameral antibiotic prophylaxis with or without postoperative topical antibiotic in cataract surgery. 61
33120637 2020
8
A rare case of aggressive posterior retinopathy of prematurity presenting with exudative retinal detachment. 61
33144201 2020
9
Toll-like receptors in acute post-cataract surgery endophthalmitis. 61
32507952 2020
10
Acute Endophthalmitis after Cataract Surgery: Clinical Characteristics and the Role of Intracameral Antibiotic Prophylaxis. 61
32956857 2020
11
Clinical Etiologies, Microbial Spectrum, Antibiotic Susceptibilities, and Visual Acuity Outcomes of Acute Endophthalmitis. 61
32609038 2020
12
Successful Treatment of Acute Endophthalmitis after Cat Bite: A Case Report and Review of the Literature. 61
33250758 2020
13
Culture-Positive Acute Post-Vitrectomy Endophthalmitis in a Silicone Oil-Filled Eye. 61
32890082 2020
14
Fulminant Acanthamoeba Endophthalmitis After Cataract Surgery-A Case Report. 61
32068610 2020
15
Management and Visual Outcomes of Acute Bacterial Endophthalmitis Following Intravitreal Injection of Contaminated Bevacizumab in a Single Day. 61
32579693 2020
16
Endophthalmitis prophylaxis study. Report 1: Intracameral cefuroxime and moxifloxacin prophylaxis for the prevention of postcataract endophthalmitis in rural India. 61
32317453 2020
17
Specific PCR and Quantitative Real-Time PCR in Ocular Samples from Acute and Delayed-Onset Postoperative Endophthalmitis. 61
31770517 2020
18
Post cataract Pseudomonas stutzeri endophthalmitis: Report of a case and review of literature. 61
31856535 2020
19
Surgical Management of Complications after Dexamethasone Implant. 61
32095301 2020
20
UTILITY OF INTRAOPERATIVE OPTICAL COHERENCE TOMOGRAPHY IN ACUTE ENDOPHTHALMITIS. 61
28858193 2020
21
Comparative Study of Microbiological Profile and Management Outcomes of Acute Endophthalmitis after Microincision Vitrectomy Surgery versus Intravitreal Injections. 61
31900009 2020
22
Changes in Management Based on Vitreous Culture in Endophthalmitis After Intravitreal Anti-vascular Endothelial Growth Factor Injection. 61
31201794 2019
23
Pseudozyma aphidis endophthalmitis post-cataract operation: Case discussion and management. 61
31198884 2019
24
International Practice Patterns for the Management of Acute Postsurgical and Postintravitreal Injection Endophthalmitis: European Vitreo-Retinal Society Endophthalmitis Study Report 1. 61
31043364 2019
25
Incidence and Characteristics of Endophthalmitis after Cataract Surgery in Poland, during 2010-2015. 61
31226859 2019
26
Controlled Release of Vancomycin From a Thermoresponsive Hydrogel System for the Prophylactic Treatment of Postoperative Acute Endophthalmitis. 61
31293808 2019
27
Acute Bacterial Endophthalmitis Following Dexamethasone Intravitreal Implant: A Case Report. 61
31080392 2019
28
The Impact of Prefilled Syringes on Endophthalmitis Following Intravitreal Injection of Ranibizumab. 61
30552891 2019
29
Safety and efficacy of intracameral moxifloxacin for prevention of post-cataract endophthalmitis: Randomized controlled clinical trial. 61
30691922 2019
30
Physical Incompatibility between Vancomycin and Viscoelastic Mimicking Acute Endophthalmitis: The First Report. 61
30863651 2019
31
Utility of MALDI-TOF mass spectrometry in an outbreak investigation of acute endophthalmitis following intravitreal injection. 61
29605188 2018
32
Association of Acute Endophthalmitis With Intravitreal Injections of Corticosteroids or Anti-Vascular Growth Factor Agents in a Nationwide Study in France. 61
30242325 2018
33
Genetic diversity and persistent colonization of Enterococcus faecalis on ocular surfaces. 61
30324322 2018
34
Filamentous gram-negative bacteria masquerading as actinomycetes in infectious endophthalmitis: a review of three cases. 61
30306353 2018
35
Aspergillus aortitis in an immunocompetent patient presenting with acute endophthalmitis. 61
30344969 2018
36
Postoperative endophthalmitis due to Pseudomonas luteola: First reported case of acute and virulent presentation from a tertiary eye care center in South India. 61
30038182 2018
37
Vitreous hemorrhage as an early sign of acute bacterial endophthalmitis following intravitreal ranibizumab injection. 61
28365853 2018
38
Intracameral moxifloxacin after cataract surgery: a prospective study. 61
29846429 2018
39
Emergency management: acute endophthalmitis. 61
30487688 2018
40
Acute Onset of Exogenous Endophthalmitis after Dexamethasone Implant Injection Treated without Implant Removal. 61
30581640 2018
41
Acute Endophthalmitis after Intravitreal Bevacizumab Injections at The Tertiary Centre in Nepal. 61
31056587 2018
42
Pseudophakic pupillary block glaucoma in early postoperative period masquerading as endophthalmitis: Clinical features are important for differential diagnosis. 61
29563695 2018
43
Incidence of acute endophthalmitis after office based intravitreal bevacizumab injection. 61
29256542 2017
44
Acute endophthalmitis after cataract surgery: 164 consecutive cases treated at a referral center in South Korea. 61
28548647 2017
45
Acute Endophthalmitis Caused by Leuconostoc spp. following Intravitreal Bevacizumab Injection. 61
29282402 2017
46
Controlled release of moxifloxacin from intraocular lenses modified by Ar plasma-assisted grafting with AMPS or SBMA: An in vitro study. 61
28531880 2017
47
Randomised controlled trial of prophylactic antibiotic treatment for the prevention of endophthalmitis after open globe injury at Groote Schuur Hospital. 61
27793818 2017
48
ACTINOMYCES NEUII ENDOPHTHALMITIS AFTER INTRAVITREAL ANTI-VASCULAR ENDOTHELIAL GROWTH FACTOR INJECTION. 61
27280342 2017
49
Drug-resistant coagulase-negative staphylococcal endophthalmitis following dexamethasone intravitreal implant. 61
28724830 2017
50
25-GAUGE TROCAR CANNULA FOR ACUTE ENDOPHTHALMITIS-RELATED IN-OFFICE VITREOUS TAP AND INJECTION: Patient Comfort and Physician Ease of Use. 61
27471824 2017

Variations for Acute Endophthalmitis

Expression for Acute Endophthalmitis

Search GEO for disease gene expression data for Acute Endophthalmitis.

Pathways for Acute Endophthalmitis

GO Terms for Acute Endophthalmitis

Cellular components related to Acute Endophthalmitis according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 adherens junction GO:0005912 8.62 VEGFA AJM1

Sources for Acute Endophthalmitis

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
17 EFO
18 ExPASy
19 FMA
20 GARD
28 GO
29 GTR
30 HMDB
31 HPO
32 ICD10
33 ICD10 via Orphanet
34 ICD9CM
35 IUPHAR
36 KEGG
37 LifeMap
39 LOVD
41 MedGen
44 MeSH
45 MESH via Orphanet
46 MGI
49 NCI
50 NCIt
51 NDF-RT
53 NINDS
54 Novoseek
56 OMIM via Orphanet
57 OMIM® (Updated 05-Mar-2021)
61 PubMed
63 QIAGEN
68 SNOMED-CT via HPO
69 TGDB
70 Tocris
71 UMLS
72 UMLS via Orphanet
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