MCID: ACT012
MIFTS: 37

Acute Hemorrhagic Conjunctivitis

Categories: Infectious diseases

Aliases & Classifications for Acute Hemorrhagic Conjunctivitis

MalaCards integrated aliases for Acute Hemorrhagic Conjunctivitis:

Name: Acute Hemorrhagic Conjunctivitis 12 15
Conjunctivitis, Acute Hemorrhagic 44 73
Viral Conjunctivitis 12 73
Epidemic Hemorrhagic Conjunctivitis 12
Apollo Disease 12

Classifications:



External Ids:

Disease Ontology 12 DOID:11227
ICD9CM 35 077.4
MeSH 44 D003232
NCIt 50 C34505
ICD10 33 B30

Summaries for Acute Hemorrhagic Conjunctivitis

Disease Ontology : 12 A viral infectious disease that results in inflammation located in conjunctiva, has material basis in Human coxsackievirus A24 or has material basis in Human enterovirus 70, which are transmitted by contaminated fomites or transmitted by contact with contaminated hands. The infection has symptom vascular dilation, has symptom eyelid edema, has symptom photophobia, has symptom redness of the eyes, has symptom watering of the eye, has symptom conjunctival congestion, and has symptom superficial punctate epithelial keratitis.

MalaCards based summary : Acute Hemorrhagic Conjunctivitis, also known as conjunctivitis, acute hemorrhagic, is related to conjunctivitis and acute conjunctivitis, and has symptoms including vascular dilation, eyelid edema and photophobia. An important gene associated with Acute Hemorrhagic Conjunctivitis is PLD3 (Phospholipase D Family Member 3), and among its related pathways/superpathways are Creation of C4 and C2 activators and Complement and coagulation cascades. Affiliated tissues include eye, kidney and endothelial, and related phenotype is immune system.

Related Diseases for Acute Hemorrhagic Conjunctivitis

Diseases related to Acute Hemorrhagic Conjunctivitis via text searches within MalaCards or GeneCards Suite gene sharing:

(show all 11)
# Related Disease Score Top Affiliating Genes
1 conjunctivitis 10.7
2 acute conjunctivitis 10.0 PLD3 PSEN2
3 inclusion conjunctivitis 10.0 PLD3 PSEN2
4 conjunctival disease 9.9 PLD3 PSEN2
5 shipyard eye 9.7
6 dermatitis 9.7
7 keratoconjunctivitis 9.7
8 dysautonomia 9.7
9 endotheliitis 9.7
10 hemoglobinuria 9.5 C5 CD55
11 paroxysmal nocturnal hemoglobinuria 9.2 C5 CD55

Graphical network of the top 20 diseases related to Acute Hemorrhagic Conjunctivitis:



Diseases related to Acute Hemorrhagic Conjunctivitis

Symptoms & Phenotypes for Acute Hemorrhagic Conjunctivitis

Symptoms:

12
  • vascular dilation
  • eyelid edema
  • photophobia
  • redness of the eyes
  • watering of the eye
  • conjunctival congestion
  • superficial punctate epithelial keratitis

MGI Mouse Phenotypes related to Acute Hemorrhagic Conjunctivitis:

46
# Description MGI Source Accession Score Top Affiliating Genes
1 immune system MP:0005387 9.02 C5 CD55 MATN3 PLD3 PSEN2

Drugs & Therapeutics for Acute Hemorrhagic Conjunctivitis

Search Clinical Trials , NIH Clinical Center for Acute Hemorrhagic Conjunctivitis

Inferred drug relations via UMLS 73 / NDF-RT 51 :


Cochrane evidence based reviews: conjunctivitis, acute hemorrhagic

Genetic Tests for Acute Hemorrhagic Conjunctivitis

Anatomical Context for Acute Hemorrhagic Conjunctivitis

MalaCards organs/tissues related to Acute Hemorrhagic Conjunctivitis:

41
Eye, Kidney, Endothelial, Colon

Publications for Acute Hemorrhagic Conjunctivitis

Articles related to Acute Hemorrhagic Conjunctivitis:

(show top 50) (show all 118)
# Title Authors Year
1
Role of enhanced receptor engagement in the evolution of a pandemic acute hemorrhagic conjunctivitis virus. ( 29284752 )
2018
2
Molecular epidemiology of acute hemorrhagic conjunctivitis caused by coxsackie A type 24 variant in China, 2004-2014. ( 28332617 )
2017
3
Acute hemorrhagic conjunctivitis epidemic in SALo Paulo State, Brazil, 2011. ( 27754516 )
2016
4
Acute hemorrhagic conjunctivitis: anti-coxsackievirus A24 variant secretory immunoglobulin A in acute and convalescent tear. ( 26392747 )
2015
5
Virological and epidemiological analysis of coxsackievirus A24 variant epidemic of acute hemorrhagic conjunctivitis in Okinawa, Japan, in 2011. ( 26109843 )
2015
6
Molecular evolution of VP3, VP1, 3C(pro) and 3D(pol) coding regions in coxsackievirus group A type 24 variant isolates from acute hemorrhagic conjunctivitis in 2011 in Okinawa, Japan. ( 24517637 )
2014
7
Genetic characteristics of the coxsackievirus A24 variant causing outbreaks of acute hemorrhagic conjunctivitis in Jiangsu, China, 2010. ( 24475191 )
2014
8
Molecular identification and phylogenetic study of coxsackievirus A24 variant isolated from an outbreak of acute hemorrhagic conjunctivitis in India in 2010. ( 23124888 )
2013
9
A molecular investigative approach to an outbreak of acute hemorrhagic conjunctivitis in Egypt, October 2010. ( 23531270 )
2013
10
Phylogenetic and molecular characterization of coxsackievirus A24 variant isolates from a 2010 acute hemorrhagic conjunctivitis outbreak in Guangdong, China. ( 22336176 )
2012
11
Molecular characterization and phylogenetic study of coxsackievirus A24v causing outbreaks of acute hemorrhagic conjunctivitis (AHC) in Brazil. ( 21858030 )
2011
12
An antiviral small-interfering RNA simultaneously effective against the most prevalent enteroviruses causing acute hemorrhagic conjunctivitis. ( 20739472 )
2011
13
Outbreak of acute hemorrhagic conjunctivitis in Yunnan, People's Republic of China, 2007. ( 20579343 )
2010
14
Understanding of acute hemorrhagic conjunctivitis (AHC) epidemics and outbreaks of Paederus spp keratoconjuctivitis, periorbital oedema ("Nairobi red eyes") and dermatitis. ( 21516962 )
2010
15
Notes from the field: acute hemorrhagic conjunctivitis outbreaks caused by coxsackievirus A24v --- Uganda and southern Sudan, 2010. ( 20724969 )
2010
16
[Outbreak of acute hemorrhagic conjunctivitis in Beijing City in 2007 caused by coxsackievirus A24 variant: molecular identification and phylogenetic analysis]. ( 19769156 )
2009
17
Multiple outbreaks of acute hemorrhagic conjunctivitis due to a variant of coxsackievirus A24: Guangdong, China, 2007. ( 18712817 )
2008
18
An outbreak of acute hemorrhagic conjunctivitis (AHC) caused by coxsackievirus A24 variant in Pakistan. ( 18638510 )
2008
19
Outbreak of acute hemorrhagic conjunctivitis in Maharashtra and Gujarat states of India, caused by Coxsackie virus A-24 variant. ( 17457917 )
2007
20
Rapid diagnosis of acute hemorrhagic conjunctivitis due to coxsackievirus A24 variant by real-time one-step RT-PCR. ( 17328967 )
2007
21
Molecular identification of coxsackievirus A24 variant, isolated from an outbreak of acute hemorrhagic conjunctivitis in Singapore in 2005. ( 17680326 )
2007
22
Two outbreaks of acute hemorrhagic conjunctivitis in Africa due to genotype III coxsackievirus A24 variant. ( 17294159 )
2007
23
Acute hemorrhagic conjunctivitis and coxsackievirus A24v, Rio de Janeiro, Brazil, 2004. ( 16704792 )
2006
24
Viral investigation of acute hemorrhagic conjunctivitis outbreak (2003) in Nepal using molecular methods. ( 17333732 )
2006
25
Acute hemorrhagic conjunctivitis epidemic caused by coxsackievirus A24 variants in Korea during 2002-2003. ( 16299722 )
2006
26
Outbreak of acute hemorrhagic conjunctivitis in French Guiana and West Indies caused by coxsackievirus A24 variant: phylogenetic analysis reveals Asian import. ( 15714481 )
2005
27
Rapid identification of the coxsackievirus A24 variant by molecular serotyping in an outbreak of acute hemorrhagic conjunctivitis. ( 15750062 )
2005
28
Towards an in vitro model for acute hemorrhagic conjunctivitis: cytokine-mediated vascular endothelial cell activation triggered by enterovirus type 70 infection. ( 15072749 )
2004
29
Acute hemorrhagic conjunctivitis outbreak caused by Coxsackievirus A24--Puerto Rico, 2003. ( 15269699 )
2004
30
Acute hemorrhagic conjunctivitis epidemic--2003 in Nepal. ( 15024766 )
2003
31
Acute hemorrhagic conjunctivitis caused by coxsackievirus A24 variant, South Korea, 2002. ( 12967504 )
2003
32
Systemic and ocular antibody responses to inactivated acute hemorrhagic conjunctivitis (AHC) virus; enterovirus 70 (EV70). ( 14566646 )
2003
33
Acute hemorrhagic conjunctivitis due to enterovirus 70 in India. ( 10221880 )
1999
34
Corneal superinfection in acute hemorrhagic conjunctivitis. ( 9820942 )
1998
35
From the Centers for Disease Control and Prevention. Acute hemorrhagic conjunctivitis--St Croix, US Virgin Islands, September-October 1998. ( 9842938 )
1998
36
Acute hemorrhagic conjunctivitis--St. Croix, U.S. Virgin Islands, September-October 1998. ( 9810014 )
1998
37
Detection of enterovirus 70 by polymerase chain reaction in acute hemorrhagic conjunctivitis. ( 8694103 )
1996
38
Acute hemorrhagic conjunctivitis outbreak in Thailand, 1992. ( 9279984 )
1996
39
Inhibition of the enteroviruses that cause acute hemorrhagic conjunctivitis (AHC) by benzimidazoles; enviroxime (LY 122772) and enviradone (LY 127123). ( 8540755 )
1995
40
Analysis of neutralizing antibodies to Enterovirus 70 and Coxsackievirus A24 variant, levels of immunoglobulins and total protein in tears of patients with acute hemorrhagic conjunctivitis. ( 22823272 )
1995
41
A recent epidemic of acute hemorrhagic conjunctivitis. ( 8394649 )
1993
42
Acute hemorrhagic conjunctivitis due to enterovirus 70 in American Samoa: serum-neutralizing antibodies and sex-specific protection. ( 1337662 )
1992
43
The complete nucleotide sequence of a variant of Coxsackievirus A24, an agent causing acute hemorrhagic conjunctivitis. ( 1317075 )
1992
44
Acute hemorrhagic conjunctivitis. ( 1309404 )
1992
45
Evolutionary study on the Coxsackievirus A 24 variant causing acute hemorrhagic conjunctivitis by oligonucleotide mapping analysis of RNA genome. ( 2171464 )
1990
46
An epidemic of acute hemorrhagic conjunctivitis in American Samoa caused by coxsackievirus A24 variant. ( 2556026 )
1989
47
Acute hemorrhagic conjunctivitis--Mexico. ( 2540410 )
1989
48
Acute hemorrhagic conjunctivitis caused by coxsackie A24 variant--Puerto Rico. ( 2828909 )
1988
49
Spread of acute hemorrhagic conjunctivitis due to enterovirus-70: effect of air temperature and relative humidity on virus survival on fomites. ( 2844979 )
1988
50
The first epidemic of acute hemorrhagic conjunctivitis due to a coxsackievirus A24 variant in Okinawa, Japan, in 1985-1986. ( 2855085 )
1988

Variations for Acute Hemorrhagic Conjunctivitis

Expression for Acute Hemorrhagic Conjunctivitis

Search GEO for disease gene expression data for Acute Hemorrhagic Conjunctivitis.

Pathways for Acute Hemorrhagic Conjunctivitis

GO Terms for Acute Hemorrhagic Conjunctivitis

Biological processes related to Acute Hemorrhagic Conjunctivitis according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 skeletal system development GO:0001501 9.16 EVC MATN3
2 complement activation, classical pathway GO:0006958 8.96 C5 CD55
3 regulation of complement activation GO:0030449 8.62 C5 CD55

Sources for Acute Hemorrhagic Conjunctivitis

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
17 ExPASy
19 FMA
28 GO
29 GTR
30 HGMD
31 HMDB
32 HPO
33 ICD10
34 ICD10 via Orphanet
35 ICD9CM
36 IUPHAR
37 KEGG
38 LifeMap
40 LOVD
42 MedGen
44 MeSH
45 MESH via Orphanet
46 MGI
49 NCI
50 NCIt
51 NDF-RT
54 NINDS
55 Novoseek
57 OMIM
58 OMIM via Orphanet
62 PubMed
64 QIAGEN
69 SNOMED-CT via HPO
70 SNOMED-CT via Orphanet
71 TGDB
72 Tocris
73 UMLS
74 UMLS via Orphanet
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