MCID: ACT065
MIFTS: 23

Acute Hemorrhagic Encephalitis

Categories: Neuronal diseases

Aliases & Classifications for Acute Hemorrhagic Encephalitis

MalaCards integrated aliases for Acute Hemorrhagic Encephalitis:

Name: Acute Hemorrhagic Encephalitis 12 15 71

Classifications:



External Ids:

Disease Ontology 12 DOID:5224
NCIt 50 C35796
UMLS 71 C1332149

Summaries for Acute Hemorrhagic Encephalitis

MalaCards based summary : Acute Hemorrhagic Encephalitis is related to dengue hemorrhagic fever and cholangitis. An important gene associated with Acute Hemorrhagic Encephalitis is SNORD83B (Small Nucleolar RNA, C/D Box 83B), and among its related pathways/superpathways are NF-kappaB Signaling and Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell. Affiliated tissues include endothelial, and related phenotype is immune system.

Related Diseases for Acute Hemorrhagic Encephalitis

Diseases related to Acute Hemorrhagic Encephalitis via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50) (show all 121)
# Related Disease Score Top Affiliating Genes
1 dengue hemorrhagic fever 29.9 ICAM1 F3 F2
2 cholangitis 29.8 ICAM1 F3 F2
3 encephalitis 10.5
4 primary hemophagocytic lymphohistiocytosis 10.3 UNC13D STX11
5 encephalopathy, acute, infection-induced 4 10.3 RANBP2 CPT2
6 gastroduodenitis 10.3 SNORD83B CD8A
7 toxicodendron dermatitis 10.2 ICAM1 CD8A
8 hemophagocytic lymphohistiocytosis, familial, 5 10.2 UNC13D STXBP2 STX11
9 hemophagocytic lymphohistiocytosis, familial, 4 10.2 UNC13D STXBP2 STX11
10 acalculous cholecystitis 10.2 SENP8 F2
11 piebald trait 10.2 UNC13D STXBP2 STX11
12 mooren's ulcer 10.2 ICAM1 CD8A
13 shwartzman phenomenon 10.2 ICAM1 F3
14 achenbach syndrome 10.2 F3 F2
15 marburg hemorrhagic fever 10.2 F3 CD8A
16 renal pelvis squamous cell carcinoma 10.2 F3 F2
17 synovial angioma 10.2 F3 F2
18 papillary adenofibroma 10.2 F3 F2
19 femoral neuropathy 10.2 F3 F2
20 emphysematous cholecystitis 10.2 F3 F2
21 giant hemangioma 10.2 F3 F2
22 hemopneumothorax 10.1 F3 F2
23 dic in newborn 10.1 F3 F2
24 cerebral falx meningioma 10.1 F3 F2
25 ankylosing spondylitis 1 10.1 F3 F2
26 waterhouse-friderichsen syndrome 10.1 F3 F2
27 pulmonary embolism and infarction 10.1 F3 F2
28 acute pulmonary heart disease 10.1 F3 F2
29 cavernous sinus thrombosis 10.1 F3 F2
30 epidural abscess 10.1 F3 F2
31 lemierre's syndrome 10.1 F3 F2
32 acute cor pulmonale 10.1 F3 F2
33 posterior cerebral artery infarction 10.1 F3 F2
34 gastric hemangioma 10.1 F3 F2
35 hepatic infarction 10.1 F3 F2
36 hemopericardium 10.1 F3 F2
37 intracranial sinus thrombosis 10.1 F3 F2
38 splenic abscess 10.1 F3 F2
39 qualitative platelet defect 10.1 F3 F2
40 mediastinitis 10.1 F3 F2
41 cerebral sinovenous thrombosis 10.1 F3 F2
42 sagittal sinus thrombosis 10.1 F3 F2
43 monkeypox 10.1 CD8A CD46
44 prothrombin deficiency 10.1 F3 F2
45 intracranial hypotension 10.1 F3 F2
46 intracranial embolism 10.1 F3 F2
47 griscelli syndrome, type 2 10.1 UNC13D STXBP2 STX11 SH2D1A
48 griscelli syndrome 10.1 UNC13D STXBP2 STX11 SH2D1A
49 acquired von willebrand syndrome 10.1 F3 F2
50 hemophagocytic lymphohistiocytosis, familial, 1 10.1 UNC13D STXBP2 STX11 SH2D1A

Graphical network of the top 20 diseases related to Acute Hemorrhagic Encephalitis:



Diseases related to Acute Hemorrhagic Encephalitis

Symptoms & Phenotypes for Acute Hemorrhagic Encephalitis

MGI Mouse Phenotypes related to Acute Hemorrhagic Encephalitis:

46
# Description MGI Source Accession Score Top Affiliating Genes
1 immune system MP:0005387 9.4 CCR2 CD8A CPT2 F2 F3 ICAM1

Drugs & Therapeutics for Acute Hemorrhagic Encephalitis

Search Clinical Trials , NIH Clinical Center for Acute Hemorrhagic Encephalitis

Genetic Tests for Acute Hemorrhagic Encephalitis

Anatomical Context for Acute Hemorrhagic Encephalitis

MalaCards organs/tissues related to Acute Hemorrhagic Encephalitis:

40
Endothelial

Publications for Acute Hemorrhagic Encephalitis

Articles related to Acute Hemorrhagic Encephalitis:

(show all 15)
# Title Authors PMID Year
1
Acute hemorrhagic leukoencephalitis in a COVID-19 patient-a case report with literature review. 61
33575849 2021
2
Acute Necrotizing Encephalopathy Associated with Influenza A. 61
32101112 2020
3
Extracellular methemoglobin promotes cyto-adherence of uninfected RBC to endothelial cells: Insight into cerebral malaria pathology. 61
30701588 2019
4
Acute Hemorrhagic Encephalitis Responding to Combined Decompressive Craniectomy, Intravenous Immunoglobulin, and Corticosteroid Therapies: Association with Novel RANBP2 Variant. 61
29593631 2018
5
Pediatric Hemorrhagic Brainstem Encephalitis Associated With HHV-7 Infection. 61
26255752 2015
6
Acute hemorrhagic encephalitis: An unusual presentation of dengue viral infection. 61
25709166 2015
7
[Acute hemorrhagic encephalitis by varicella-zoster virus in a patient with SLE]. 61
12924281 2003
8
Acute hemorrhagic encephalitis (Hurst disease) associated with neuroaxonal dystrophy. 61
10079604 1998
9
[Acute hemorrhagic encephalitis of Hurst. Clinical, electroencephalographic and anatomic presentation of a case from the literature and revue]. 61
1153966 1975
10
[Acute hemorrhagic encephalitis]. 61
13408818 1956
11
Acute hemorrhagic encephalitis. 61
13334758 1956
12
[Acute hemorrhagic encephalitis following intake of osarsol]. 61
13351919 1956
13
[Acute hemorrhagic encephalitis]. 61
13235932 1954
14
[Clinical and pathological aspects of primary acute hemorrhagic encephalitis]. 61
15433370 1950
15
Acute hemorrhagic encephalitis of tuberculous origin; report of case. 61
15406180 1949

Variations for Acute Hemorrhagic Encephalitis

Expression for Acute Hemorrhagic Encephalitis

Search GEO for disease gene expression data for Acute Hemorrhagic Encephalitis.

Pathways for Acute Hemorrhagic Encephalitis

Pathways related to Acute Hemorrhagic Encephalitis according to GeneCards Suite gene sharing:

# Super pathways Score Top Affiliating Genes
1 11.44 SH2D1A CD8A CD46 CCR2
2 11.26 SH2D1A ICAM1 CD8A

GO Terms for Acute Hemorrhagic Encephalitis

Cellular components related to Acute Hemorrhagic Encephalitis according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 external side of plasma membrane GO:0009897 9.1 MOG ICAM1 F2 CXCL9 CD8A CCR2

Biological processes related to Acute Hemorrhagic Encephalitis according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 viral process GO:0016032 9.72 RANBP2 MOG ICAM1 CD46 CCR2
2 exocytosis GO:0006887 9.54 UNC13D STXBP2 STX11
3 viral entry into host cell GO:0046718 9.43 MOG ICAM1 CD46
4 T cell mediated immunity GO:0002456 9.16 CD8A CD46
5 regulation of mast cell degranulation GO:0043304 8.96 UNC13D STXBP2
6 cellular defense response GO:0006968 8.8 SH2D1A CXCL9 CCR2

Molecular functions related to Acute Hemorrhagic Encephalitis according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 virus receptor activity GO:0001618 8.8 MOG ICAM1 CD46

Sources for Acute Hemorrhagic Encephalitis

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
17 EFO
18 ExPASy
19 FMA
20 GARD
28 GO
29 GTR
30 HMDB
31 HPO
32 ICD10
33 ICD10 via Orphanet
34 ICD9CM
35 IUPHAR
36 KEGG
37 LifeMap
39 LOVD
41 MedGen
44 MeSH
45 MESH via Orphanet
46 MGI
49 NCI
50 NCIt
51 NDF-RT
53 NINDS
54 Novoseek
56 OMIM via Orphanet
57 OMIM® (Updated 05-Mar-2021)
61 PubMed
63 QIAGEN
68 SNOMED-CT via HPO
69 TGDB
70 Tocris
71 UMLS
72 UMLS via Orphanet
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