MCID: ACT065
MIFTS: 24

Acute Hemorrhagic Encephalitis

Categories: Neuronal diseases

Aliases & Classifications for Acute Hemorrhagic Encephalitis

MalaCards integrated aliases for Acute Hemorrhagic Encephalitis:

Name: Acute Hemorrhagic Encephalitis 12 15 71

Classifications:



External Ids:

Disease Ontology 12 DOID:5224
NCIt 49 C35796
UMLS 71 C1332149

Summaries for Acute Hemorrhagic Encephalitis

MalaCards based summary : Acute Hemorrhagic Encephalitis is related to dengue disease and dengue hemorrhagic fever. An important gene associated with Acute Hemorrhagic Encephalitis is SNORD83B (Small Nucleolar RNA, C/D Box 83B), and among its related pathways/superpathways are NF-kappaB Signaling and NF-kappa B signaling pathway. Affiliated tissues include endothelial, and related phenotypes are hematopoietic system and immune system

Related Diseases for Acute Hemorrhagic Encephalitis

Diseases related to Acute Hemorrhagic Encephalitis via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50) (show all 171)
# Related Disease Score Top Affiliating Genes
1 dengue disease 29.8 SENP8 ICAM1 CD8A CD40LG
2 dengue hemorrhagic fever 29.7 F3 F2 CD40LG
3 cholangitis 29.5 F3 F2 CD40LG
4 encephalopathy, acute, infection-induced 4 10.5 RANBP2 CPT2
5 gastroduodenitis 10.5 SNORD83B CD40LG
6 hemophagocytic lymphohistiocytosis, familial, 5 10.5 STXBP2 STX11
7 kunjin encephalitis 10.4 SENP8 CD40LG
8 kyasanur forest disease 10.4 SENP8 CD40LG
9 st. louis encephalitis 10.4 SENP8 CD40LG
10 heterophyiasis 10.4 ICAM1 CD40LG
11 cork-handlers' disease 10.4 CD8A CD40LG
12 primary hemophagocytic lymphohistiocytosis 10.4 UNC13D STXBP2 STX11
13 encephalitis 10.4
14 asymptomatic dengue 10.4 SENP8 CD40LG
15 hemophagocytic lymphohistiocytosis, familial, 4 10.4 UNC13D STXBP2 STX11
16 transient hypogammaglobulinemia of infancy 10.3 SH2D1A CD40LG
17 erythema infectiosum 10.3 SENP8 CD40LG
18 piebald trait 10.3 UNC13D STXBP2 STX11
19 heparin-induced thrombocytopenia 10.3 F3 CD40LG
20 early yaws 10.3 CD8A CD40LG
21 astrakhan spotted fever 10.3 F3 CD40LG
22 norwegian scabies 10.3 CD8A CD40LG
23 hemophagocytic lymphohistiocytosis, familial, 3 10.3 UNC13D STX11 SH2D1A
24 diabetic peripheral angiopathy 10.3 ICAM1 F3
25 toxicodendron dermatitis 10.3 ICAM1 CD8A
26 retroperitoneal lymphoma 10.3 F2 CD40LG
27 catastrophic antiphospholipid syndrome 10.3 F3 CD40LG
28 murray valley encephalitis 10.3 SENP8 CD40LG
29 exanthema subitum 10.3 SNORD83A CD46 CD40LG
30 viral exanthem 10.3 CD8A CD40LG
31 tertiary syphilis 10.3 CD8A CD40LG
32 acute retinal necrosis syndrome 10.3 CD8A CD40LG
33 zika fever 10.3 SENP8 CD40LG
34 alkhurma hemorrhagic fever 10.3 F3 CD40LG
35 splenic abscess 10.2 F2 CD40LG
36 achenbach syndrome 10.2 F3 F2
37 cerebritis 10.2 CD8A CD40LG
38 granulomatous hepatitis 10.2 CD8A CD40LG
39 synovial angioma 10.2 F3 F2
40 renal pelvis squamous cell carcinoma 10.2 F3 F2
41 papillary adenofibroma 10.2 F3 F2
42 blue toe syndrome 10.2 F3 F2
43 emphysematous cholecystitis 10.2 F3 F2
44 femoral neuropathy 10.2 F3 F2
45 lateral sinus thrombosis 10.2 F3 F2
46 giant hemangioma 10.2 F3 F2
47 dic in newborn 10.2 F3 F2
48 waterhouse-friderichsen syndrome 10.2 F3 F2
49 acalculous cholecystitis 10.2 SENP8 F2 CD40LG
50 cavernous sinus thrombosis 10.2 F3 F2

Graphical network of the top 20 diseases related to Acute Hemorrhagic Encephalitis:



Diseases related to Acute Hemorrhagic Encephalitis

Symptoms & Phenotypes for Acute Hemorrhagic Encephalitis

MGI Mouse Phenotypes related to Acute Hemorrhagic Encephalitis:

45
# Description MGI Source Accession Score Top Affiliating Genes
1 hematopoietic system MP:0005397 9.73 CCR2 CD40LG CD8A F2 F3 ICAM1
2 immune system MP:0005387 9.44 CCR2 CD40LG CD8A CPT2 F2 F3

Drugs & Therapeutics for Acute Hemorrhagic Encephalitis

Search Clinical Trials , NIH Clinical Center for Acute Hemorrhagic Encephalitis

Genetic Tests for Acute Hemorrhagic Encephalitis

Anatomical Context for Acute Hemorrhagic Encephalitis

MalaCards organs/tissues related to Acute Hemorrhagic Encephalitis:

40
Endothelial

Publications for Acute Hemorrhagic Encephalitis

Articles related to Acute Hemorrhagic Encephalitis:

(show all 14)
# Title Authors PMID Year
1
Acute Necrotizing Encephalopathy Associated with Influenza A. 61
32101112 2020
2
Extracellular methemoglobin promotes cyto-adherence of uninfected RBC to endothelial cells: Insight into cerebral malaria pathology. 61
30701588 2019
3
Acute Hemorrhagic Encephalitis Responding to Combined Decompressive Craniectomy, Intravenous Immunoglobulin, and Corticosteroid Therapies: Association with Novel RANBP2 Variant. 61
29593631 2018
4
Pediatric Hemorrhagic Brainstem Encephalitis Associated With HHV-7 Infection. 61
26255752 2015
5
Acute hemorrhagic encephalitis: An unusual presentation of dengue viral infection. 61
25709166 2015
6
[Acute hemorrhagic encephalitis by varicella-zoster virus in a patient with SLE]. 61
12924281 2003
7
Acute hemorrhagic encephalitis (Hurst disease) associated with neuroaxonal dystrophy. 61
10079604 1998
8
[Acute hemorrhagic encephalitis of Hurst. Clinical, electroencephalographic and anatomic presentation of a case from the literature and revue]. 61
1153966 1975
9
[Acute hemorrhagic encephalitis]. 61
13408818 1956
10
Acute hemorrhagic encephalitis. 61
13334758 1956
11
[Acute hemorrhagic encephalitis following intake of osarsol]. 61
13351919 1956
12
[Acute hemorrhagic encephalitis]. 61
13235932 1954
13
[Clinical and pathological aspects of primary acute hemorrhagic encephalitis]. 61
15433370 1950
14
Acute hemorrhagic encephalitis of tuberculous origin; report of case. 61
15406180 1949

Variations for Acute Hemorrhagic Encephalitis

Expression for Acute Hemorrhagic Encephalitis

Search GEO for disease gene expression data for Acute Hemorrhagic Encephalitis.

Pathways for Acute Hemorrhagic Encephalitis

Pathways related to Acute Hemorrhagic Encephalitis according to GeneCards Suite gene sharing:

# Super pathways Score Top Affiliating Genes
1 11.87 SH2D1A CD8A CD46 CD40LG CCR2
2 11.35 XIAP ICAM1 CD40LG
3 11.05 SH2D1A ICAM1 CD8A CD40LG

GO Terms for Acute Hemorrhagic Encephalitis

Cellular components related to Acute Hemorrhagic Encephalitis according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 external side of plasma membrane GO:0009897 9.17 MOG ICAM1 F2 CXCL9 CD8A CD40LG

Biological processes related to Acute Hemorrhagic Encephalitis according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 viral process GO:0016032 9.77 RANBP2 MOG ICAM1 CD46 CCR2
2 viral entry into host cell GO:0046718 9.5 MOG ICAM1 CD46
3 T cell mediated immunity GO:0002456 9.26 CD8A CD46
4 regulation of mast cell degranulation GO:0043304 9.16 UNC13D STXBP2
5 cellular defense response GO:0006968 9.13 SH2D1A CXCL9 CCR2
6 regulation of immune response GO:0050776 9.02 SH2D1A MOG ICAM1 CD8A CD40LG

Molecular functions related to Acute Hemorrhagic Encephalitis according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 virus receptor activity GO:0001618 8.8 MOG ICAM1 CD46

Sources for Acute Hemorrhagic Encephalitis

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
17 EFO
18 ExPASy
19 FMA
28 GO
29 GTR
30 HMDB
31 HPO
32 ICD10
33 ICD10 via Orphanet
34 ICD9CM
35 IUPHAR
36 KEGG
37 LifeMap
39 LOVD
41 MedGen
43 MeSH
44 MESH via Orphanet
45 MGI
48 NCI
49 NCIt
50 NDF-RT
53 NINDS
54 Novoseek
56 OMIM
57 OMIM via Orphanet
61 PubMed
63 QIAGEN
68 SNOMED-CT via HPO
69 TGDB
70 Tocris
71 UMLS
72 UMLS via Orphanet
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