Aliases & Classifications for Acute Insulin Response

MalaCards integrated aliases for Acute Insulin Response:

Name: Acute Insulin Response 58 13
Air 58 3

External Ids:

OMIM 58 601676

Summaries for Acute Insulin Response

CDC : 3 Outdoor air quality has improved since the 1990s, but many challenges remain in protecting Americans from air quality problems. Ground-level ozone, the main part of smog, and particle pollution are just two of the many threats to air quality and public health in the United States.

MalaCards based summary : Acute Insulin Response, also known as air, is related to apnea, obstructive sleep and hyperinsulinism. An important gene associated with Acute Insulin Response is AIR (Acute Insulin Response (2)), and among its related pathways/superpathways are Aldosterone synthesis and secretion and Glucose / Energy Metabolism. The drugs Liraglutide and Zinc have been mentioned in the context of this disorder. Affiliated tissues include lung, heart and bone, and related phenotypes are Increased cell death in breast cancer cell lines (MCF10A, MDA-MB-435) and Reduced mammosphere formation

Description from OMIM: 601676

Related Diseases for Acute Insulin Response

Diseases related to Acute Insulin Response via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50) (show all 1026)
# Related Disease Score Top Affiliating Genes
1 apnea, obstructive sleep 31.7 CRP INS
2 hyperinsulinism 30.0 ABCC8 INS KCNJ11 KCNJ5
3 gestational diabetes 29.6 INS KCNJ11 TCF7L2
4 glucose intolerance 29.4 CRP GCG INS
5 hypoglycemia 29.3 ABCC8 GCG INS KCNJ11
6 dumping syndrome 29.3 GCG INS
7 gastrointestinal system disease 29.0 CRP GCG INS
8 diabetes mellitus 28.4 ABCC8 CRP GCG INS KCNJ11 PIK3R1
9 body mass index quantitative trait locus 11 27.8 ADRB2 CRP GCG INS PIK3R1 UCP1
10 diabetes mellitus, noninsulin-dependent 27.7 ABCC8 CRP GCG INS KCNJ11 PIK3R1
11 intellectual deficit buenos-aires type 12.4
12 mental retardation, buenos aires type 12.2
13 ventilation pneumonitis 12.0
14 pneumothorax, primary spontaneous 11.6
15 respiratory failure 11.6
16 autoimmune polyendocrine syndrome, type i, with or without reversible metaphyseal dysplasia 11.5
17 lung disease 11.4
18 pulmonary disease, chronic obstructive 11.4
19 bronchitis 11.4
20 allergic rhinitis 11.4
21 pneumonia 11.4
22 asthma 11.4
23 interstitial lung disease 11.4
24 cryptogenic organizing pneumonia 11.4
25 pneumothorax 11.4
26 streptococcal group a invasive disease 11.3
27 sick building syndrome 11.3
28 autoimmune polyendocrine syndrome type 1 11.3
29 mycobacterium tuberculosis 1 11.3
30 bronchiectasis 11.3
31 pulmonary alveolar microlithiasis 11.3
32 q fever 11.3
33 lymphangioleiomyomatosis 11.3
34 chikungunya 11.3
35 autoimmune retinopathy 11.3
36 bronchiolitis 11.2
37 legionnaires' disease 11.2
38 influenza 11.2
39 pollen allergy 11.2
40 pulmonary edema 11.2
41 acute respiratory distress syndrome 11.2
42 sleep apnea 11.2
43 meniere disease 11.2
44 sinusitis 11.2
45 mouth disease 11.2
46 tracheoesophageal fistula 11.2
47 mucormycosis 11.2
48 palatopharyngeal incompetence 11.1
49 pneumocystosis 11.1
50 patulous eustachian tube 11.1

Graphical network of the top 20 diseases related to Acute Insulin Response:



Diseases related to Acute Insulin Response

Symptoms & Phenotypes for Acute Insulin Response

Clinical features from OMIM:

601676

GenomeRNAi Phenotypes related to Acute Insulin Response according to GeneCards Suite gene sharing:

27
# Description GenomeRNAi Source Accession Score Top Affiliating Genes
1 Increased cell death in breast cancer cell lines (MCF10A, MDA-MB-435) GR00104-A-0 9.13 INS PIK3R1 TCF7L2
2 Reduced mammosphere formation GR00396-S 9.1 ABCC8 KCNJ11 KCNJ5 PIK3R1 PYGM UCP2

MGI Mouse Phenotypes related to Acute Insulin Response:

47
# Description MGI Source Accession Score Top Affiliating Genes
1 adipose tissue MP:0005375 9.73 ADRB2 INS KCNJ11 PIK3R1 TCF7L2 UCP1
2 cardiovascular system MP:0005385 9.7 ADRB2 CRP INS KCNJ11 KCNJ5 PIK3R1
3 homeostasis/metabolism MP:0005376 9.65 ABCC8 ADRB2 CRP INS KCNJ11 PIK3R1
4 muscle MP:0005369 9.1 ADRB2 INS KCNJ11 PIK3R1 PYGM TCF7L2

Drugs & Therapeutics for Acute Insulin Response

Drugs for Acute Insulin Response (from DrugBank, HMDB, Dgidb, PharmGKB, IUPHAR, NovoSeek, BitterDB):

(show top 50) (show all 173)
# Name Status Phase Clinical Trials Cas Number PubChem Id
1
Liraglutide Approved Phase 4 204656-20-2 44147092
2
Zinc Approved, Investigational Phase 4,Phase 2,Not Applicable 7440-66-6 32051
3
Clozapine Approved Phase 4 5786-21-0 2818
4
Rosiglitazone Approved, Investigational Phase 4 122320-73-4 77999
5 Menaquinone Approved, Investigational Phase 4 1182-68-9
6
Phylloquinone Approved, Investigational Phase 4 84-80-0
7
Norgestimate Approved, Investigational Phase 4 35189-28-7 6540478
8
Ethinyl Estradiol Approved Phase 4 57-63-6 5991
9
Estradiol Approved, Investigational, Vet_approved Phase 4 50-28-2 5757
10
Polyestradiol phosphate Approved Phase 4 28014-46-2
11
Moxifloxacin Approved, Investigational Phase 4 354812-41-2, 151096-09-2 152946
12
Pioglitazone Approved, Investigational Phase 4,Not Applicable 111025-46-8 4829
13
Protein C Approved Phase 4
14
Etanercept Approved, Investigational Phase 4,Phase 3,Phase 1,Phase 2 185243-69-0
15
Menadione Approved, Nutraceutical Phase 4 58-27-5 4055
16
Serine Approved, Nutraceutical Phase 4 56-45-1 5951
17
Menatetrenone Investigational Phase 4 863-61-6 5282367
18 Hormones Phase 4,Phase 2,Phase 1,Not Applicable
19 Incretins Phase 4,Phase 2,Phase 1,Not Applicable
20 Insulin, Globin Zinc Phase 4,Phase 3,Phase 2,Phase 1,Not Applicable
21 insulin Phase 4,Phase 3,Phase 2,Phase 1,Not Applicable
22 Hormone Antagonists Phase 4,Phase 2,Phase 1,Not Applicable
23 Hormones, Hormone Substitutes, and Hormone Antagonists Phase 4,Phase 2,Phase 1,Not Applicable
24 Hypoglycemic Agents Phase 4,Phase 3,Phase 2,Phase 1,Not Applicable
25 HIV Protease Inhibitors Phase 4,Phase 3,Phase 2,Not Applicable
26
protease inhibitors Phase 4,Phase 3,Phase 2,Not Applicable
27 Dipeptidyl-Peptidase IV Inhibitors Phase 4,Phase 3,Phase 2,Not Applicable
28 Sitagliptin Phosphate Phase 4,Phase 2,Not Applicable
29 Glucagon-Like Peptide 1 Phase 4,Not Applicable
30 Liver Extracts Phase 4,Phase 1,Phase 2,Not Applicable
31 Tranquilizing Agents Phase 4
32 Central Nervous System Depressants Phase 4,Not Applicable
33 Neurotransmitter Agents Phase 4
34 Serotonin Antagonists Phase 4
35 Psychotropic Drugs Phase 4
36 Serotonin Agents Phase 4
37 Antipsychotic Agents Phase 4
38 GABA Agents Phase 4
39 Vitamins Phase 4
40 Vitamin K Phase 4
41 Hemostatics Phase 4
42 Antifibrinolytic Agents Phase 4
43 Trace Elements Phase 4,Not Applicable
44 Micronutrients Phase 4,Not Applicable
45 Coagulants Phase 4,Not Applicable
46 Vitamin K 2 Phase 4
47 Vitamin MK 7 Phase 4
48 Nutrients Phase 4,Not Applicable
49 naphthoquinone Phase 4
50 Estrogens Phase 4

Interventional clinical trials:

(show all 48)
# Name Status NCT ID Phase Drugs
1 Effect of Liraglutide Combined With Short-term CSII on Long-term Glycemic Remission and β Cell Function Unknown status NCT01790308 Phase 4 CSII;Liraglutide
2 Beta-cell Function in Glucose Abnormalities and Acute Myocardial Infarction Completed NCT00627744 Phase 4 Sitagliptin
3 Liraglutide Actions on the Liver: Effects on Glucose Phosphorylation Not yet recruiting NCT02198209 Phase 4 Liraglutide
4 Rosiglitazone for Clozapine Induced Glucose Metabolism Impairment Completed NCT00337350 Phase 4 rosiglitazone;placebo
5 The Effect of Vitamin K Supplementation on Glucose Metabolism Completed NCT00960973 Phase 4 Menatetrenone;Placebo
6 Oral Contraceptives, Insulin Resistance and Cardiovascular Risk Profile in Pre-Menopausal Women Completed NCT01475513 Phase 4 Ortho Cyclen®
7 Pioglitazone Incretin Study Completed NCT00656864 Phase 4 Pioglitazone;Placebo
8 Anti-inflammatory Therapy to Improve Outcomes After TPIAT Recruiting NCT02713997 Phase 4 etanercept;Alpha 1-Antitrypsin
9 Study to Evaluate the Effects of Colesevelam on Insulin Sensitivity and ß-Cell Function in Subjects With Impaired Fasting Glucose (Prediabetes) Completed NCT00990184 Phase 3 Colesevelam
10 A Study to Evaluate the Effects of Vildagliptin on the Insulin Response to Glucose in Subjects With Pre-diabetes Completed NCT00312130 Phase 3 Vildagliptin
11 Diet and Medical Therapy Versus Bariatric Surgery in Type 2 Diabetes Completed NCT00888836 Phase 2, Phase 3
12 Islet Transplantation in Type 1 Diabetes Completed NCT00434811 Phase 3 Sirolimus;Tacrolimus
13 Evaluation of Superiority of Valsartan+Celecoxib+Metformin Over Metformin Alone in Type 2 Diabetes Patients Not yet recruiting NCT03686657 Phase 1, Phase 2 Metformin;Val, Cel and Met XR Low;Val, Cel and Met XR High
14 Evaluation of the Efficacy of Intramuscular Islet Autograft After Extensive Pancreatectomy Recruiting NCT02872571 Phase 1, Phase 2 Intramuscular Islet Autograft
15 Incretin Effect and Use After Clinical Islet Transplantation Completed NCT00768651 Phase 2 Pantoprazole;Sitagliptin
16 Omental Islet Transplant Active, not recruiting NCT02821026 Phase 1, Phase 2 Anti-Thymocyte Globulin;Mycophenolate mofetil;Tacrolimus;Etanercept;Sirolimus
17 Peritransplant Deoxyspergualin in Islet Transplantation in Type 1 Diabetes Completed NCT00434850 Phase 2 Deoxyspergualin;Sirolimus;Tacrolimus
18 Safety and Effectiveness of Low Molecular Weight Sulfated Dextran in Islet Transplantation Completed NCT00789308 Phase 2 Low Molecular Weight Sulfated Dextran (LMW-SD);Heparin;CellCept® (Mycophenolate mofetil) OR Rapamune® (Sirolimus);Prograf® (Tacrolimus) OR Cyclosporine;Thymoglobulin® (Anti-thymocyte Globulin) - at first transplant;Simulect® (Basiliximab) - at 2nd or 3rd transplant;Klexane® (Enoxaparinsodium);Trombyl® or Albyl-E® (Acetylsalicylicacid- ASA);Enbrel® (Etanercept)
19 LEA29Y (Belatacept) Emory Edmonton Protocol Completed NCT00468403 Phase 2 Mycophenolate Mofetil;Tacrolimus
20 To Compare the Effect of a Subcutaneous Canakinumab Administration to Placebo in Patients With Impaired Glucose Tolerance or Patients With Type 2 Diabetes With Differing Baseline Diabetes Therapies Completed NCT01068860 Phase 2 Canakinumab 150 mg;Placebo to Canakinumab
21 The Effects of LY2409021 on the Liver Completed NCT01588366 Phase 1 Placebo;LY2409021
22 Exenatide and Weight Loss for Diabetes Prevention Completed NCT02084654 Phase 1 Exenatide 5 and 10 mcg 2 times a day;placebo
23 Islet Allotransplantation in Type 1 Diabetes Enrolling by invitation NCT01705899 Phase 1 Human Pancreatic Islets
24 Effects of Short-term Intensive Insulin Therapy in Newly Diagnosed Type 2 Diabetes Patients Unknown status NCT01588743 Not Applicable insulin aspart
25 Changes in Glucose Metabolism After Roux-en-Y Gastric Bypass Unknown status NCT01993511
26 Effect of Exenatide, Sitagliptin or Glimepiride on Functional ß -Cell Mass Completed NCT00775684 Not Applicable Exenatide;Sitagliptin;Glimepiride
27 Effects of Progressive Negative Energy Balance on Glucose Tolerance, Insulin Sensitivity, and Beta-cell Function Active, not recruiting NCT03264001 Not Applicable
28 Sucralose Effects on Glucose Metabolism and Gut Microbiota Completed NCT02650947 Not Applicable
29 Nutrigenomics of Zinc Supplementation in Insulin Secretion and Diabetes Completed NCT00981448 Not Applicable
30 Characterization of the Incretinpathy in Type 2 Diabetes Initiated After Sixty Years Old Completed NCT00843232
31 Restoration of Beta Cell Function and Cardiovascular Parameters in Relation to Adipoinsular and Enteroinsular Axes After Gastric Bypass Surgery Completed NCT01271062 Not Applicable
32 The Aging Endocrine Pancreas: Characterization of the Entero-insular Axis Physiology in the Elderly Completed NCT00843479
33 Long Term Metabolic Safety of Norditropin® Treatment of Small for Gestational Age (SGA) Subjects Completed NCT00787878 somatropin;No treatment given;No treatment given
34 Aldosterone and Glucose Homeostasis Completed NCT00732160 Not Applicable Aldosterone infusion (A);Vehicle Infusion (V)
35 Role of Pancreatic Triglyceride Content in Beta-cell Function Completed NCT00602953
36 Effect of Dietary Glycemic Index on Beta-cell Function Active, not recruiting NCT01386645 Not Applicable high glycemic index diet plus N-acetylcysteine
37 Effect of Sitagliptin on Short-Term Metabolic Dysregulation of Oral Glucocorticoid Therapy Completed NCT01488279 Not Applicable Dexamethasone 2.5 mg and Sitagliptin 100 mg;Dexamethasone 2.5 mg and placebo tablet
38 Effect of Different Interventions on Glycemic Control and β-cell Function in Newly Diagnosed Type 2 Diabetic Patients Completed NCT01147627 Not Applicable exenatide injection;Mixed Protamine Zinc Recombinant Human Insulin Lispro 25R;Pioglitazone
39 Effects of Continuous Positive Airway Pressure (CPAP) on Glucose Metabolism Completed NCT01503164 Not Applicable
40 Epigenetic Regulation of Human Adipose Tissue Distribution Active, not recruiting NCT02728635 Not Applicable
41 Chromium Picolinate for the Treatment of Metabolic Syndrome Completed NCT00128154 Not Applicable Chromium picolinate
42 Sleep Loss and Mechanisms of Impaired Glucose Metabolism Completed NCT00555750 Not Applicable eszopiclone;placebo
43 Characterization of Diabetes Mellitus in Fibrous Dysplasia/McCune-Albright Syndrome Recruiting NCT03520153
44 Effect of Egg Consumption on Cardiometabolic Health in Prediabetic Subjects. Recruiting NCT03332927 Not Applicable
45 Lean Beef Consumption and Insulin Sensitivity in Men and Women With Risk Factors for Diabetes Active, not recruiting NCT03202680 Not Applicable
46 Pathogenesis of Youth Onset Type 2 Diabetes and Prediabetes Recruiting NCT03195400
47 MicroRNA as Biomarkers for Development of Metabolic Syndrome in Women With Polycystic Ovary Syndrome Completed NCT03142633
48 Effects of Corn and Coconut Oils on Lipoprotein Lipids, Insulin Sensitivity and Inflammation Completed NCT03202654 Not Applicable

Search NIH Clinical Center for Acute Insulin Response

Genetic Tests for Acute Insulin Response

Anatomical Context for Acute Insulin Response

MalaCards organs/tissues related to Acute Insulin Response:

42
Lung, Heart, Bone, Brain, Liver, Testes, Breast

Publications for Acute Insulin Response

Articles related to Acute Insulin Response:

(show top 50) (show all 3042)
# Title Authors Year
1
The effectiveness of air-free warming systems on perioperative hypothermia in total hip and knee arthroplasty: A systematic review and meta-analysis. ( 31083262 )
2019
2
Brain Fog: Does Air Pollution Make Us Less Productive? ( 31084450 )
2019
3
Association of particulate matter air pollution and itch: a digital epidemiology approach. ( 31085267 )
2019
4
National air pollution distribution in China and related geographic, gaseous pollutant, and socio-economic factors. ( 31085487 )
2019
5
Effect of Air Tamponade on Tilt of the Intraocular Lens after Phacovitrectomy. ( 31085933 )
2019
6
Repeated evolution of drag reduction at the air-water interface in diving kingfishers. ( 31088257 )
2019
7
Low to Moderate Air Pollutant Exposure and Acute Respiratory Distress Syndrome after Severe Trauma. ( 30067389 )
2019
8
Climate change, air pollution, and biodiversity in Asia Pacific: impact on allergic diseases. ( 31089453 )
2019
9
Low Levels of Air Pollution and Health: Effect Estimates, Methodological Challenges, and Future Directions. ( 31090042 )
2019
10
Gender Differences in Gulf War Illness: A Re-analysis of Data From the CDC Air Force Study Using CDC and Modified Kansas Case Definitions. ( 31090678 )
2019
11
Ambient air pollution in China. ( 31090988 )
2019
12
Body composition and growth in full-term small for gestational age and large for gestational age Swedish infants assessed with air displacement plethysmography at birth and at 3-4 months of age. ( 31091240 )
2019
13
Air-Coupled and Resonant Pulse-Echo Ultrasonic Technique. ( 31091721 )
2019
14
Air quality monitoring assessment during the 2016 Olympic Games in Rio de Janeiro, Brazil. ( 31093831 )
2019
15
APPLICABILITY OF AUTONOMOUS UNMANNED HELICOPTER SURVEY OF AIR DOSE RATE IN SUBURBAN AREA. ( 31095340 )
2019
16
Exposure to outdoor air pollution and its human health outcomes: A scoping review. ( 31095592 )
2019
17
Characterizing grassland fire activity in the Flint Hills region and air quality using satellite and routine surface monitor data. ( 31096365 )
2019
18
Giant Phospholipid Folds on Air-Water Surface: Structure Details, Formation Pathway and Possible Recycle Mechanism. ( 31084004 )
2019
19
Giant cell carcinoma of the lung presenting as an isolated cyst containing air: A case report. ( 31096508 )
2019
20
Influence of a perfluorohexane-enriched atmosphere on the viscoelasticity and structural order of self-assembled nanodomains of semifluorinated alkanes at the air/water interface. ( 31083773 )
2019
21
Metal-organic frameworks with photocatalytic bactericidal activity for integrated air cleaning. ( 31097709 )
2019
22
Planning and Design of Low-Power-Consuming Full-Outer-Air-Intake Natural Air-Conditioning System. ( 31098009 )
2019
23
Aqueous phase nitrile hydration catalyzed by an in-situ generated air stable ruthenium catalyst. ( 31099144 )
2019
24
Ambient particulate air pollution and circulating C-reactive protein level: A systematic review and meta-analysis. ( 31103472 )
2019
25
Anatomy of the winter 2017 air quality emergency in Delhi. ( 31103667 )
2019
26
Interventions to reduce ambient particulate matter air pollution and their effect on health. ( 31106396 )
2019
27
Long-term microbial community dynamics at two full-scale biotrickling filters treating pig house exhaust air. ( 31106964 )
2019
28
Understanding the role of air and protein phase on mechanical anisotropy of calcium caseinate fibers. ( 31108819 )
2019
29
Pneumatic Colorectal Injury Caused by High Pressure Compressed Air. ( 31109160 )
2019
30
Aerial drone as a carrier for miniaturized air sampling systems. ( 31030954 )
2019
31
The Effect of Forced-Air Warmer, Ondansetron or their Combination on Shivering in Pregnant Women Coming for Elective Cesarean Section under Spinal Anesthesia: A Prospective, Randomized Controlled Comparative Study. ( 31031474 )
2019
32
Could the Air You Breathe Increase Your Risk of Developing Acute Respiratory Distress Syndrome? ( 30133313 )
2019
33
Anorexia nervosa presenting as diffuse spontaneous air leaks. ( 30755429 )
2019
34
Myo-inositol mediates the effects of traffic-related air pollution on generalized anxiety symptoms at age 12 years. ( 31103795 )
2019
35
Association between Exposure to Ambient Air Pollution and Rheumatoid Arthritis in Adults. ( 30959862 )
2019
36
Air Pollution Exposure and Asthma Incidence in Children: Demonstrating the Value of Air Quality Standards. ( 31112243 )
2019
37
Association of Changes in Air Quality With Incident Asthma in Children in California, 1993-2014. ( 31112259 )
2019
38
Indoor Endotoxin Exposure and Ambient Air Pollutants Interact on Asthma Outcomes. ( 31063402 )
2019
39
Can the effects of outdoor air pollution on asthma be mitigated? ( 31029773 )
2019
40
Synergistic Association of House Endotoxin Exposure and Ambient Air Pollution with Asthma Outcomes. ( 30965018 )
2019
41
Predictors of residential mobility and its impact on air pollution exposure among children diagnosed with early childhood leukemia. ( 30770842 )
2019
42
Association between Outdoor Air Pollution and Childhood Leukemia: A Systematic Review and Dose-Response Meta-Analysis. ( 31017485 )
2019
43
A Meta-analysis of Traffic-related Air Pollution and Risk of Childhood Leukemia. ( 31026249 )
2019
44
Bayesian modeling of hematologic cancer and vehicular air pollution among young people in the city of São Paulo, Brazil. ( 31025573 )
2019
45
Hypospadias risk is increased with maternal residential exposure to hormonally active hazardous air pollutants. ( 30694020 )
2019
46
Hypospadias Risk from Maternal Residential Exposure to Heavy Metal Hazardous Air Pollutants. ( 30875870 )
2019
47
Pulmonary interstitial emphysema is a risk factor for poor prognosis and a cause of air leaks. ( 31043328 )
2019
48
Early recurrence of ileocolic intussusception after successful air enema reduction: incidence and predisposing factors. ( 30143943 )
2019
49
Long-Term Exposure to Ambient Ozone and Progression of Subclinical Arterial Disease: The Multi-Ethnic Study of Atherosclerosis and Air Pollution. ( 31063398 )
2019
50
The Association between Long-Term Air Pollution and Urinary Catecholamines: Evidence from the Multi-Ethnic Study of Atherosclerosis. ( 31095432 )
2019

Variations for Acute Insulin Response

Expression for Acute Insulin Response

Search GEO for disease gene expression data for Acute Insulin Response.

Pathways for Acute Insulin Response

Pathways related to Acute Insulin Response according to GeneCards Suite gene sharing:

(show all 13)
# Super pathways Score Top Affiliating Genes
1
Show member pathways
12.5 ABCC8 ADRB2 GCG INS KCNJ11 KCNJ5
2 12.22 GCG INS UCP1 UCP2
3
Show member pathways
12.07 ABCC8 GCG INS KCNJ11
4
Show member pathways
11.95 GCG INS TCF7L2
5
Show member pathways
11.84 ABCC8 KCNJ11 KCNJ5
6
Show member pathways
11.71 ABCC8 KCNJ11 KCNJ5
7
Show member pathways
11.67 INS PIK3R1 PYGM
8
Show member pathways
11.54 ABCC8 INS KCNJ11 PIK3R1
9 11.28 ADRB2 INS PIK3R1
10 11.21 ABCC8 KCNJ11 PIK3R1
11 11.09 INS PIK3R1
12 11 ABCC8 ADRB2 KCNJ11 KCNJ5
13 10.57 ABCC8 INS KCNJ11 UCP2

GO Terms for Acute Insulin Response

Cellular components related to Acute Insulin Response according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 inward rectifying potassium channel GO:0008282 8.62 ABCC8 KCNJ11

Biological processes related to Acute Insulin Response according to GeneCards Suite gene sharing:

(show all 16)
# Name GO ID Score Top Affiliating Genes
1 positive regulation of protein kinase B signaling GO:0051897 9.69 INS PIK3R1 TCF7L2
2 potassium ion transport GO:0006813 9.67 ABCC8 KCNJ11 KCNJ5
3 positive regulation of cold-induced thermogenesis GO:0120162 9.58 ADRB2 UCP1 UCP2
4 acute-phase response GO:0006953 9.56 CRP INS
5 positive regulation of glucose import GO:0046326 9.55 INS PIK3R1
6 negative regulation of insulin secretion GO:0046676 9.54 ABCC8 KCNJ11
7 brown fat cell differentiation GO:0050873 9.52 ADRB2 UCP1
8 mitochondrial transport GO:0006839 9.48 UCP1 UCP2
9 cellular glucose homeostasis GO:0001678 9.46 ABCC8 PIK3R1
10 regulation of protein localization to plasma membrane GO:1903076 9.43 INS PIK3R1
11 negative regulation of blood vessel diameter GO:0097756 9.37 CRP INS
12 regulation of insulin secretion GO:0050796 9.33 KCNJ11 GCG ABCC8
13 adaptive thermogenesis GO:1990845 9.32 UCP1 UCP2
14 diet induced thermogenesis GO:0002024 9.26 ADRB2 UCP1
15 mitochondrial transmembrane transport GO:1990542 8.96 UCP1 UCP2
16 response to cold GO:0009409 8.8 ADRB2 UCP2 UCP1

Molecular functions related to Acute Insulin Response according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 insulin receptor binding GO:0005158 9.32 INS PIK3R1
2 inward rectifier potassium channel activity GO:0005242 9.26 KCNJ11 KCNJ5
3 insulin-like growth factor receptor binding GO:0005159 9.16 INS PIK3R1
4 ATP-activated inward rectifier potassium channel activity GO:0015272 8.65 KCNJ11
5 oxidative phosphorylation uncoupler activity GO:0017077 8.62 UCP1 UCP2

Sources for Acute Insulin Response

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
17 EFO
18 ExPASy
20 FMA
29 GO
30 GTR
31 HGMD
32 HMDB
33 HPO
34 ICD10
35 ICD10 via Orphanet
36 ICD9CM
37 IUPHAR
38 KEGG
39 LifeMap
41 LOVD
43 MedGen
45 MeSH
46 MESH via Orphanet
47 MGI
50 NCI
51 NCIt
52 NDF-RT
55 NINDS
56 Novoseek
58 OMIM
59 OMIM via Orphanet
63 PubMed
65 QIAGEN
70 SNOMED-CT via HPO
71 SNOMED-CT via Orphanet
72 TGDB
73 Tocris
74 UMLS
75 UMLS via Orphanet
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