MCID: ACT029
MIFTS: 49

Acute Interstitial Pneumonia

Categories: Rare diseases, Respiratory diseases

Aliases & Classifications for Acute Interstitial Pneumonia

MalaCards integrated aliases for Acute Interstitial Pneumonia:

Name: Acute Interstitial Pneumonia 12 54 15 74
Hamman-Rich Syndrome 12 54 74
Acute Interstitial Pneumonitis 12 54
Idiopathic Pulmonary Fibrosis, Acute Fatal Form 12
Accelerated Interstitial Pneumonia 12
Idiopathic Pulmonary Fibrosis 74
Hamman-Rich Disease 12
Aip 12

Classifications:



External Ids:

Disease Ontology 12 DOID:2800
ICD9CM 36 516.33
NCIt 51 C35806
SNOMED-CT 69 35037009 45157009
ICD10 34 J84.114

Summaries for Acute Interstitial Pneumonia

NIH Rare Diseases : 54 Acute interstitial pneumonia (AIP) is a rare and serious condition that affects the lungs. The signs and symptoms generally develop and progress rapidly. In the early stages of the condition, affected people may experience upper respiratory and/or viral-like symptoms such as cough, shortness of breath, and fever. This is followed by the rapid onset of respiratory failure and the need for mechanical ventilation in the majority of cases. The underlying cause of AIP is unknown. Most cases occur sporadically in people with no family history of the condition. There is, unfortunately, no proven treatment for AIP. Supportive care is generally recommended to address the signs and symptoms of the condition. Glucocorticoid therapy and other immunosuppressive therapies are often used; however, the benefits of these treatments remain unclear.

MalaCards based summary : Acute Interstitial Pneumonia, also known as hamman-rich syndrome, is related to idiopathic interstitial pneumonia and pulmonary fibrosis, idiopathic, and has symptoms including dyspnea on exertion and dry cough. An important gene associated with Acute Interstitial Pneumonia is SFTPD (Surfactant Protein D), and among its related pathways/superpathways are Bacterial infections in CF airways and Phagosome. The drugs Sodium Citrate and Bosentan have been mentioned in the context of this disorder. Affiliated tissues include lung, pituitary and testes, and related phenotype is Increased virus production.

Disease Ontology : 12 A idiopathic interstitial pneumonia which develops suddenly and is severe. Initially, the lung shows edema, hyaline membranes, and interstitial acute inflammation. Later,it develops loose organizing fibrosis, mostly within alveolar septa and type II pneumocyte hyperplasia. Fever, cough, and difficulty breathing develop over 1 to 2 weeks, typically progressing to acute respiratory failure.

Related Diseases for Acute Interstitial Pneumonia

Diseases related to Acute Interstitial Pneumonia via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50) (show all 124)
# Related Disease Score Top Affiliating Genes
1 idiopathic interstitial pneumonia 31.7 SFTPA1 SFTPA2 SFTPD
2 pulmonary fibrosis, idiopathic 31.5 MUC1 SERPINH1 SFTPA1 SFTPA2 SFTPD
3 pulmonary fibrosis 29.9 SFTPA1 SFTPA2 SFTPD
4 porphyria, acute intermittent 12.3
5 aip-related familial isolated pituitary adenomas 12.2
6 acromegaly 12.1
7 pituitary adenoma 1, multiple types 12.1
8 pituitary adenoma, prolactin-secreting 12.0
9 autoimmune pancreatitis 11.9
10 adenoma 11.7
11 pituitary adenoma 11.7
12 familial isolated pituitary adenoma 11.7
13 gigantism 11.6
14 pituitary tumors 11.5
15 pituitary apoplexy 11.5
16 acroleukopathy, symmetric 11.5
17 hepatitis b 11.3
18 chester porphyria 11.2
19 carney complex variant 11.1
20 multiple endocrine neoplasia, type iv 11.1
21 cell type benign neoplasm 11.1
22 endocrine organ benign neoplasm 11.1
23 pituitary infarct 11.1
24 hyperpituitarism 11.1
25 pituitary gland disease 11.1
26 functioning pituitary adenoma 11.1
27 hormone producing pituitary cancer 11.1
28 growth hormone secreting pituitary adenoma 11.1
29 cancer-associated retinopathy 11.1
30 autoimmune pancreatitis type 2 11.1
31 autoimmune pancreatitis type 1 11.1
32 acth-secreting pituitary adenoma 11.1
33 pituitary adenoma 4, acth-secreting 11.0
34 silent pituitary adenoma 11.0
35 null pituitary adenoma 11.0
36 pneumonia 10.8
37 porphyria 10.4
38 pancreatitis 10.4
39 surfactant metabolism dysfunction, pulmonary, 2 10.2
40 lymphoma 10.2
41 mitral valve stenosis 10.2
42 encephalitis 10.2
43 rapidly involuting congenital hemangioma 10.2
44 acute respiratory distress syndrome 10.2
45 multiple endocrine neoplasia 10.1
46 rheumatoid arthritis 10.1
47 arthritis 10.1
48 pleuroparenchymal fibroelastosis 10.1 MUC1 SFTPD
49 helix syndrome 10.1
50 dermatomyositis 10.0

Graphical network of the top 20 diseases related to Acute Interstitial Pneumonia:



Diseases related to Acute Interstitial Pneumonia

Symptoms & Phenotypes for Acute Interstitial Pneumonia

UMLS symptoms related to Acute Interstitial Pneumonia:


dyspnea on exertion, dry cough

GenomeRNAi Phenotypes related to Acute Interstitial Pneumonia according to GeneCards Suite gene sharing:

27
# Description GenomeRNAi Source Accession Score Top Affiliating Genes
1 Increased virus production GR00378-A 8.62 MUC1 SFTPD

Drugs & Therapeutics for Acute Interstitial Pneumonia

Drugs for Acute Interstitial Pneumonia (from DrugBank, HMDB, Dgidb, PharmGKB, IUPHAR, NovoSeek, BitterDB):

(show top 50) (show all 242)
# Name Status Phase Clinical Trials Cas Number PubChem Id
1
Sodium Citrate Approved, Investigational Phase 4,Phase 3,Phase 2,Phase 1 68-04-2
2
Bosentan Approved, Investigational Phase 4,Phase 3,Phase 2 147536-97-8 104865
3
Pirfenidone Approved, Investigational Phase 4,Phase 3,Phase 2,Phase 1,Not Applicable 53179-13-8 40632
4
Nintedanib Approved Phase 4,Phase 3,Phase 2,Phase 1,Not Applicable 656247-17-5 56843413
5
Citric Acid Approved, Nutraceutical, Vet_approved Phase 4,Phase 3,Phase 2,Phase 1 77-92-9 311
6 Phosphodiesterase Inhibitors Phase 4,Phase 3,Phase 2
7 Sildenafil Citrate Phase 4,Phase 3,Phase 2 171599-83-0
8 Vasodilator Agents Phase 4,Phase 2,Phase 3,Phase 1
9 Citrate Phase 4,Phase 3,Phase 2,Phase 1
10 Phosphodiesterase 5 Inhibitors Phase 4,Phase 3,Phase 2
11 Endothelin Receptor Antagonists Phase 4,Phase 3,Phase 2
12 Antihypertensive Agents Phase 4,Phase 3,Phase 2,Not Applicable
13 Peripheral Nervous System Agents Phase 4,Phase 3,Phase 2,Phase 1,Not Applicable
14 Antirheumatic Agents Phase 4,Phase 3,Phase 2,Phase 1,Not Applicable
15 Anti-Inflammatory Agents Phase 4,Phase 3,Phase 2,Phase 1,Not Applicable
16 Analgesics, Non-Narcotic Phase 4,Phase 3,Phase 2,Phase 1,Not Applicable
17 Anti-Inflammatory Agents, Non-Steroidal Phase 4,Phase 3,Phase 2,Phase 1,Not Applicable
18 Analgesics Phase 4,Phase 3,Phase 2,Phase 1,Not Applicable
19
Minocycline Approved, Investigational Phase 3 10118-90-8 5281021
20
Iloprost Approved, Investigational Phase 2, Phase 3 78919-13-8 6443959
21
Acetylcysteine Approved, Investigational Phase 3,Phase 2,Phase 1 616-91-1 12035
22
Azathioprine Approved Phase 3,Phase 1,Phase 2,Not Applicable 446-86-6 2265
23
Prednisone Approved, Vet_approved Phase 3,Phase 2,Phase 1,Not Applicable 53-03-2 5865
24
Cyclophosphamide Approved, Investigational Phase 3,Phase 1,Phase 2 50-18-0, 6055-19-2 2907
25
Methylprednisolone Approved, Vet_approved Phase 3,Phase 1,Phase 2,Not Applicable 83-43-2 6741
26
Prednisolone phosphate Approved, Vet_approved Phase 3,Phase 1,Phase 2,Not Applicable 302-25-0
27
Prednisolone Approved, Vet_approved Phase 3,Phase 1,Phase 2,Not Applicable 50-24-8 5755
28
Methylprednisolone hemisuccinate Approved Phase 3,Phase 1,Phase 2,Not Applicable 2921-57-5
29
Mycophenolic acid Approved Phase 3 24280-93-1 446541
30
rituximab Approved Phase 3,Phase 1,Phase 2,Not Applicable 174722-31-7 10201696
31
Sargramostim Approved, Investigational Phase 3 123774-72-1, 83869-56-1
32
Lenograstim Approved, Investigational Phase 3,Phase 1,Phase 2 135968-09-1
33
leucovorin Approved Phase 3,Phase 2,Phase 1 58-05-9 143 6006
34
Losartan Approved Phase 2, Phase 3,Not Applicable 114798-26-4 3961
35
Angiotensin II Approved, Investigational Phase 2, Phase 3,Not Applicable 11128-99-7, 68521-88-0, 4474-91-3 172198
36
Fentanyl Approved, Illicit, Investigational, Vet_approved Phase 3 437-38-7 3345
37
Sulfamethoxazole Approved Phase 3 723-46-6 5329
38
Trimethoprim Approved, Vet_approved Phase 3 738-70-5 5578
39
Doxycycline Approved, Investigational, Vet_approved Phase 3 564-25-0 54671203
40
Ambrisentan Approved, Investigational Phase 3 177036-94-1 6918493
41
Warfarin Approved Phase 3 81-81-2 54678486 6691
42
Calcium Approved, Nutraceutical Phase 3 7440-70-2 271
43
Folic Acid Approved, Nutraceutical, Vet_approved Phase 3,Phase 2,Phase 1 59-30-3 6037
44
Prednisolone hemisuccinate Experimental Phase 3,Phase 1,Phase 2,Not Applicable 2920-86-7
45 Anti-Bacterial Agents Phase 3,Phase 2,Not Applicable
46 Anti-Infective Agents Phase 3,Phase 2,Phase 1,Not Applicable
47 Platelet Aggregation Inhibitors Phase 2, Phase 3
48 Immunologic Factors Phase 3,Phase 2,Phase 1,Not Applicable
49 Immunosuppressive Agents Phase 3,Phase 1,Phase 2,Not Applicable
50 Anticoagulants Phase 3,Not Applicable

Interventional clinical trials:

(show top 50) (show all 362)
# Name Status NCT ID Phase Drugs
1 Acute Effect of Sildenafil on Exercise Tolerance and Functional Capacity in COPD, IPF and Post Pneumonectomy Patients Unknown status NCT01382368 Phase 4 Sildenafil
2 Bosentan in Pulmonary Hypertension in Interstitial Lung Disease Treatment Study Unknown status NCT00637065 Phase 4 Bosentan;Placebo
3 Pirfenidone in Progressive Interstitial Lung Disease Associated With Clinically Amyopathic Dermatomyositis Unknown status NCT02821689 Phase 4 Pirfenidone
4 Safety and Tolerability Study of Pirfenidone in Combination With Nintedanib in Participants With Idiopathic Pulmonary Fibrosis (IPF) Completed NCT02598193 Phase 4 Nintedanib;Pirfenidone
5 Effect of Nintedanib on Biomarkers of Extracellular Matrix Turnover in Patients With Idiopathic Pulmonary Fibrosis and Limited Forced Vital Capacity Impairment Completed NCT02788474 Phase 4 nintedanib;placebo
6 Digital Auscultation Test - IPF Data Collection Completed NCT03503188 Phase 4
7 Safety, Tolerability and PK of Nintedanib in Combination With Pirfenidone in IPF Completed NCT02579603 Phase 4 Nintedanib;Pirfenidone
8 A Study to Compare the Amount of Nintedanib and Pirfenidone in the Blood When Nintedanib and Pirfenidone Are Given Separately or in Combination Completed NCT02606877 Phase 4 nintedanib;pirfenidone
9 Study of Pulmonary Rehabilitation in Patients With Idiopathic Pulmonary Fibrosis (IPF) Recruiting NCT03717012 Phase 4 Nintedanib
10 Management of Progressive Disease in Idiopathic Pulmonary Fibrosis Not yet recruiting NCT03939520 Phase 4 pirfenidone and nintedanib;pirfenidone or nintedanib
11 68Ga-DOTA-NOC PET/CT in Patients With Idiopathic Pulmonary Fibrosis Terminated NCT01321996 Phase 4
12 Pulmonary Hypertension Secondary to Idiopathic Pulmonary Fibrosis And Treatment With Sildenafil Withdrawn NCT00625079 Phase 4 sildenafil
13 Pulmonary Arterial Hypertension Secondary to Idiopathic Pulmonary Fibrosis and Treatment With Bosentan Withdrawn NCT00625469 Phase 4 bosentan
14 Minocycline Therapy for Lung Scarring in Patients With Idiopathic Pulmonary Fibrosis - a Pilot Study Unknown status NCT00203697 Phase 3 minocycline
15 Trial of Iloprost in Pulmonary Hypertension Secondary to Pulmonary Fibrosis Unknown status NCT00439543 Phase 2, Phase 3 Iloprost inhalation
16 Treatment of Chronic Cough in Idiopathic Pulmonary Fibrosis With Thalidomide Completed NCT00600028 Phase 3 Thalidomide;Placebo
17 Open Label Extension Study in Patients With Idiopathic Pulmonary Fibrosis Who Completed Protocol AC-052-321/ BUILD 3 / NCT00391443 Completed NCT00631475 Phase 3 Bosentan
18 Clinical Study of ART-123 for the Treatment of Acute Exacerbation of Idiopathic Pulmonary Fibrosis Completed NCT02739165 Phase 3 ART-123;Placebo
19 Efficacy and Safety of Pirfenidone in Patients With Idiopathic Pulmonary Fibrosis (IPF) Completed NCT01366209 Phase 3 Pirfenidone;Placebo
20 Efficacy and Safety of Nintedanib Co-administered With Sildenafil in Idiopathic Pulmonary Fibrosis Patients With Advanced Lung Function Impairment Completed NCT02802345 Phase 3 Nintedanib;Placebo;Sildenafil
21 Efficacy and Safety of Oral Bosentan in Patients With Idiopathic Pulmonary Fibrosis Completed NCT00071461 Phase 2, Phase 3 bosentan;Placebo
22 Three-Arm Study of the Safety and Efficacy of Pirfenidone in Patients With Idiopathic Pulmonary Fibrosis Completed NCT00287716 Phase 3 Pirfenidone;Placebo
23 Safety and Efficacy of Pirfenidone in Patients With Idiopathic Pulmonary Fibrosis Completed NCT00287729 Phase 3 Pirfenidone;Placebo
24 BUILD 3: Bosentan Use in Interstitial Lung Disease Completed NCT00391443 Phase 3 Bosentan;Placebo
25 Gleevec Idiopathic Pulmonary Fibrosis (IPF) Study Completed NCT00131274 Phase 2, Phase 3 Imatinib Mesylate (Gleevec)
26 Nintedanib Twice Daily vs Placebo in Patients Diagnosed With Idiopathic Pulmonary Fibrosis (IPF) Completed NCT01979952 Phase 3 Matching Placebo;Nintedanib
27 Sildenafil Trial of Exercise Performance in Idiopathic Pulmonary Fibrosis Completed NCT00517933 Phase 3 Sildenafil Citrate
28 Open-Label Study of the Long Term Safety of Pirfenidone in Patients With Idiopathic Pulmonary Fibrosis (IPF) Completed NCT00662038 Phase 3 pirfenidone
29 A Study of the Safety and Efficacy Interferon-Gamma 1b in Patients With Idiopathic Pulmonary Fibrosis (IPF) Completed NCT00047645 Phase 3 Interferon-gamma 1b
30 Study of the Effects of High-dose N-acetylcysteine (NAC) in Idiopathic Pulmonary Fibrosis (IPF) Completed NCT00639496 Phase 3 n-acetylcysteine;placebo
31 Safety and Efficacy of BIBF 1120 at High Dose in Idiopathic Pulmonary Fibrosis Patients Completed NCT01335464 Phase 3 placebo;BIBF 1120
32 Safety and Efficacy of BIBF 1120 at High Dose in Idiopathic Pulmonary Fibrosis Patients II Completed NCT01335477 Phase 3 placebo;BIBF 1120
33 Phase III Study on Rotavirus Vaccine to Evaluate Lot-to-lot Consistency and Interference With Routine UIP Immunization Completed NCT02584816 Phase 3
34 Evaluating the Effectiveness of Prednisone, Azathioprine, and N-acetylcysteine in Patients With IPF Completed NCT00650091 Phase 3 N-acetylcysteine (NAC);Placebo
35 A Study of Mycophenolate Mofetil (CellCept) in Lung Transplant Recipients Completed NCT01014442 Phase 3 mycophenolate mofetil
36 Rituximab in Rheumatoid Arthritis Lung Disease Completed NCT00578565 Phase 3 Rituximab
37 A Trial to Compare Nintedanib With Placebo for Patients With Scleroderma Related Lung Fibrosis Completed NCT02597933 Phase 3 Nintedanib;Placebo
38 High Dose Cyclophosphamide for Treatment of Scleroderma Completed NCT00501995 Phase 3 IV Cyclophosphamide
39 EZ-2053 in the Prophylaxis of Acute Pulmonary Allograft Rejection Completed NCT00105183 Phase 3
40 Efficacy and Safety of Oral Bosentan in Pulmonary Fibrosis Associated With Scleroderma Completed NCT00070590 Phase 2, Phase 3 Bosentan
41 A Clinical Study to Test How Effective and Safe GLPG1690 is for Subjects With Idiopathic Pulmonary Fibrosis (IPF) When Used Together With Standard of Care Recruiting NCT03733444 Phase 3 GLPG1690;Placebo
42 A Clinical Study to Test How Effective and Safe GLPG1690 is for Subjects With Idiopathic Pulmonary Fibrosis (IPF) When Used Together With Standard of Care Recruiting NCT03711162 Phase 3 GLPG1690;Placebo
43 Cyclophosphamide for Acute Exacerbation of Idiopathic Pulmonary Fibrosis Recruiting NCT02460588 Phase 3 Cyclophosphamide;Placebo;Corticosteroid (prednisolone)
44 Nebulized Fentanyl in Patients With Mild to Moderate Idiopathic Pulmonary Fibrosis and Chronic Dyspnea Recruiting NCT03018756 Phase 3 Fentanyl Citrate;Placebo
45 CleanUP IPF for the Pulmonary Trials Cooperative Recruiting NCT02759120 Phase 3 Antimicrobial therapy: Co-trimoxazole or Doxycycline
46 Open-label Study to Assess the Effectiveness of Pirfenidone in Participants With Idiopathic Pulmonary Fibrosis (IPF). Active, not recruiting NCT03208933 Phase 3 Pirfenidone
47 Extension Trial of the Long Term Safety of BIBF 1120 in Patients With Idiopathic Pulmonary Fibrosis Active, not recruiting NCT01619085 Phase 3 BIBF 1120
48 Efficacy and Safety of Nintedanib in Patients With Progressive Fibrosing Interstitial Lung Disease (PF-ILD) Active, not recruiting NCT02999178 Phase 3 Nintedanib;Placebo
49 Evaluation of Efficacy and Safety of Pamrevlumab in Patients With Idiopathic Pulmonary Fibrosis Not yet recruiting NCT03955146 Phase 3 Pamrevlumab;Placebo
50 Pirfenidone as Treatment of Skin Fibrosis in Systemic Sclerosis Not yet recruiting NCT03068234 Phase 2, Phase 3 Pirfenidone;Placebo oral capsule;Steroids

Search NIH Clinical Center for Acute Interstitial Pneumonia

Inferred drug relations via UMLS 74 / NDF-RT 52 :


Genetic Tests for Acute Interstitial Pneumonia

Anatomical Context for Acute Interstitial Pneumonia

MalaCards organs/tissues related to Acute Interstitial Pneumonia:

42
Lung, Pituitary, Testes, Bone, Bone Marrow, Heart, Skeletal Muscle

Publications for Acute Interstitial Pneumonia

Articles related to Acute Interstitial Pneumonia:

(show top 50) (show all 151)
# Title Authors Year
1
Up-regulation of THY1 attenuates interstitial pulmonary fibrosis and promotes lung fibroblast apoptosis during acute interstitial pneumonia by blockade of the WNT signaling pathway. ( 30829553 )
2019
2
Incidental tracheal bronchus in a case of Hamman-Rich syndrome. ( 31092498 )
2019
3
Extracorporeal Membrane Oxygenation for Refractory Severe Respiratory Failure in Acute Interstitial Pneumonia. ( 29323413 )
2018
4
Acute interstitial pneumonia as first presentation of anti-synthetase syndrome: an atypical case. ( 29644083 )
2018
5
Pneumocystis jirovecii infection in patients with acute interstitial pneumonia. ( 29891174 )
2018
6
Hamman-Rich syndrome. ( 29159034 )
2018
7
A 45-Year-Old Woman with Acute Interstitial Pneumonia (Hamman-Rich Syndrome). ( 28868178 )
2017
8
Abruptio Placentae with Type II Respiratory Failure Secondary to Acute Interstitial Pneumonia Responsive to Steroids. ( 28969741 )
2017
9
Hamman-Rich syndrome: a forgotten entity. ( 28635201 )
2017
10
Successful treatment of gemcitabine-induced acute interstitial pneumonia with imatinib mesylate: a case report. ( 27733144 )
2016
11
Primary Sjogren's Syndrome Presenting as Acute Interstitial Pneumonitis/Hamman-Rich Syndrome. ( 27818685 )
2016
12
A case of catastrophic antiphospholipid syndrome, which presented an acute interstitial pneumonia-like image on chest CT scan. ( 24533549 )
2015
13
Acute interstitial pneumonia following heroin inhalation. ( 25065663 )
2015
14
Leflunomide-induced acute interstitial pneumonia in a patient treated for rheumatoid arthritis. ( 25577534 )
2015
15
Feedlot Acute Interstitial Pneumonia. ( 26253266 )
2015
16
A fatal case of acute interstitial pneumonia (AIP) in a woman affected by glioblastoma. ( 24410308 )
2014
17
High-resolution computed tomography findings of acute respiratory distress syndrome, acute interstitial pneumonia, and acute exacerbation of idiopathic pulmonary fibrosis. ( 24480142 )
2014
18
Serum heat shock protein 47 levels are elevated in acute interstitial pneumonia. ( 24650086 )
2014
19
Alveolar epithelial cells undergo epithelial-mesenchymal transition in acute interstitial pneumonia: a case report. ( 24755111 )
2014
20
Concurrent acute interstitial pneumonia and pulmonary embolism during treatment with peginterferon alpha-2a and ribavirin in a patient with hepatitis C. ( 25097288 )
2014
21
Acute interstitial pneumonia caused by interleukin-2 and interferon α-2b therapy for renal cell carcinoma: a case report and clinical study. ( 25430469 )
2014
22
Fatal outcome in a case of dermatomyositis and Hamman-Rich syndrome. ( 25326409 )
2014
23
[Acute interstitial pneumonia in patient with rheumatoid arthritis treated with leflunomide]. ( 25339568 )
2014
24
Successful combination therapy with corticosteroids, biweekly intravenous pulse cyclophosphamide and cyclosporin A for acute interstitial pneumonia in patients with dermatomyositis : report of three cases. ( 23629432 )
2013
25
Efficacy of infliximab in the treatment for dermatomyositis with acute interstitial pneumonia: a study of fourteen cases and literature review. ( 23715693 )
2013
26
Hamman-Rich syndrome revisited: how to avoid misdiagnosis. ( 22443176 )
2013
27
Coadministration of cyclosporin a with prednisolone in acute interstitial pneumonia complicating polymyositis/dermatomyositis. ( 22442637 )
2012
28
Lymphatic fluctuation in the parenchymal remodeling stage of acute interstitial pneumonia, organizing pneumonia, nonspecific interstitial pneumonia and idiopathic pulmonary fibrosis. ( 22488224 )
2012
29
Acute interstitial pneumonia (AIP): relationship to Hamman-Rich syndrome, diffuse alveolar damage (DAD), and acute respiratory distress syndrome (ARDS). ( 23001802 )
2012
30
Fatal acute interstitial pneumonia in a worker making chips from wooden debris generated by the Great East Japan earthquake and tsunami. ( 23199976 )
2012
31
Pathological changes preceding radiological changes in a patient with acute interstitial pneumonia. ( 23257539 )
2012
32
Clinical management of acute interstitial pneumonia: a case report. ( 23316404 )
2012
33
Sorafenib-induced acute interstitial pneumonia in patients with advanced hepatocellular carcinoma: report of three cases. ( 24672586 )
2012
34
Acute interstitial pneumonia (hamman-rich syndrome) as a cause of idiopathic acute respiratory distress syndrome. ( 21687544 )
2011
35
Acute interstitial pneumonia (Hamman-Rich syndrome) in idiopathic pulmonary fibrosis and bronchoalveolar carcinoma: a case report. ( 22336655 )
2011
36
Successful erlotinib rechallenge after gefitinib-induced acute interstitial pneumonia. ( 20581580 )
2010
37
Acute interstitial pneumonia-Hamman-Rich syndrome: clinical characteristics and diagnostic and therapeutic considerations. ( 19095855 )
2009
38
Clinically occult subpleural fibrosis and acute interstitial pneumonia a precursor to idiopathic pulmonary fibrosis? ( 18399864 )
2008
39
Acute interstitial pneumonia in siblings: a case report. ( 18583894 )
2008
40
Acute interstitial pneumonia in feedlot cattle: effects of feeding feather meal or vitamin E. ( 17479779 )
2007
41
An immunohistochemical study in a fatal case of acute interstitial pneumonitis (Hamman-Rich syndrome) in a 15-year-old boy presenting as sudden death. ( 17208399 )
2007
42
Early intervention can improve clinical outcome of acute interstitial pneumonia. ( 16537878 )
2006
43
Effect of dietary melengestrol acetate on the incidence of acute interstitial pneumonia in feedlot heifers. ( 16850945 )
2006
44
Acute interstitial pneumonia following surgery for primary lung cancer. ( 16893654 )
2006
45
Leflunomide-related acute interstitial pneumonia in two patients with rheumatoid arthritis: autopsy findings with a mosaic pattern of acute and organizing diffuse alveolar damage. ( 17039315 )
2006
46
Acute interstitial pneumonia and acute exacerbations of idiopathic pulmonary fibrosis. ( 17195142 )
2006
47
Leflunomide induced acute interstitial pneumonia. ( 15940779 )
2005
48
A case of lepidic pulmonary metastasis from adenocarcinoma of the gallbladder mimicking acute interstitial pneumonia. ( 16223618 )
2005
49
Video-assisted thoracoscopic lung biopsy as a possible cause of acute interstitial pneumonia in a patient with nonspecific interstitial pneumonia. ( 15510251 )
2004
50
Acute interstitial pneumonia. ( 15564019 )
2004

Variations for Acute Interstitial Pneumonia

Expression for Acute Interstitial Pneumonia

Search GEO for disease gene expression data for Acute Interstitial Pneumonia.

Pathways for Acute Interstitial Pneumonia

Pathways related to Acute Interstitial Pneumonia according to GeneCards Suite gene sharing:

# Super pathways Score Top Affiliating Genes
1
Show member pathways
11.76 MUC1 SFTPA1 SFTPD
2 11.68 SFTPA1 SFTPA2 SFTPD
3
Show member pathways
11.4 SFTPA1 SFTPA2 SFTPD
4 11.31 SFTPA1 SFTPA2
5 11.2 SFTPA1 SFTPA2
6
Show member pathways
10.99 SFTPA1 SFTPA2 SFTPD
7
Show member pathways
10.77 SFTPA1 SFTPA2 SFTPD
8
Show member pathways
10.2 SFTPA1 SFTPA2 SFTPD

GO Terms for Acute Interstitial Pneumonia

Cellular components related to Acute Interstitial Pneumonia according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 extracellular space GO:0005615 9.77 MUC1 SERPINH1 SFTPA1 SFTPA2 SFTPD
2 rough endoplasmic reticulum GO:0005791 9.43 SFTPA1 SFTPA2 SFTPD
3 multivesicular body GO:0005771 9.33 SFTPA1 SFTPA2 SFTPD
4 lamellar body GO:0042599 9.32 SFTPA1 SFTPA2
5 clathrin-coated endocytic vesicle GO:0045334 9.13 SFTPA1 SFTPA2 SFTPD
6 collagen trimer GO:0005581 8.92 SERPINH1 SFTPA1 SFTPA2 SFTPD

Biological processes related to Acute Interstitial Pneumonia according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 cellular protein metabolic process GO:0044267 9.5 SFTPA1 SFTPA2 SFTPD
2 positive regulation of phagocytosis GO:0050766 9.43 SFTPA1 SFTPA2 SFTPD
3 toll-like receptor signaling pathway GO:0002224 9.33 SFTPA1 SFTPA2 SFTPD
4 respiratory gaseous exchange GO:0007585 9.13 SFTPA1 SFTPA2 SFTPD
5 surfactant homeostasis GO:0043129 8.8 SFTPA1 SFTPA2 SFTPD

Molecular functions related to Acute Interstitial Pneumonia according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 carbohydrate binding GO:0030246 9.33 SFTPA1 SFTPA2 SFTPD
2 lipopolysaccharide binding GO:0001530 9.13 SFTPA1 SFTPA2 SFTPD
3 monosaccharide binding GO:0048029 8.8 SFTPA1 SFTPA2 SFTPD

Sources for Acute Interstitial Pneumonia

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
17 EFO
18 ExPASy
20 FMA
29 GO
30 GTR
31 HGMD
32 HMDB
33 HPO
34 ICD10
35 ICD10 via Orphanet
36 ICD9CM
37 IUPHAR
38 KEGG
39 LifeMap
41 LOVD
43 MedGen
45 MeSH
46 MESH via Orphanet
47 MGI
50 NCI
51 NCIt
52 NDF-RT
55 NINDS
56 Novoseek
58 OMIM
59 OMIM via Orphanet
63 PubMed
65 QIAGEN
70 SNOMED-CT via HPO
71 SNOMED-CT via Orphanet
72 TGDB
73 Tocris
74 UMLS
75 UMLS via Orphanet
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