MCID: ACT071
MIFTS: 54

Acute Kidney Failure

Categories: Nephrological diseases, Genetic diseases

Aliases & Classifications for Acute Kidney Failure

MalaCards integrated aliases for Acute Kidney Failure:

Name: Acute Kidney Failure 38 12 15
Pre-Renal Acute Kidney Injury 73
Kidney Failure, Acute 73
Acute Renal Failure 76
Renal Failure Acute 55

Classifications:



External Ids:

Disease Ontology 12 DOID:3021
ICD10 33 N17 N17.1 N17.2

Summaries for Acute Kidney Failure

MalaCards based summary : Acute Kidney Failure, also known as pre-renal acute kidney injury, is related to myeloma, multiple and malignant hypertension. An important gene associated with Acute Kidney Failure is MGAT3-AS1 (MGAT3 Antisense RNA 1
Circulating long noncoding RNA TapSaki is a predictor of mortality in critically ill patients with acute kidney injury
Dysfunction Pattern: Expression), and among its related pathways/superpathways is Embryonic and Induced Pluripotent Stem Cell Differentiation Pathways and Lineage-specific Markers. The drugs Dopamine and Fenoldopam have been mentioned in the context of this disorder. Affiliated tissues include Bone and Adipose, and related phenotypes are cardiovascular system and homeostasis/metabolism

Wikipedia : 76 Acute kidney injury (AKI), previously called acute renal failure (ARF), is an abrupt loss of kidney... more...

Related Diseases for Acute Kidney Failure

Diseases in the Kidney Disease family:

Acute Kidney Failure Chronic Kidney Failure
Renal Infectious Disease Ren-Related Kidney Disease

Diseases related to Acute Kidney Failure via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50) (show all 83)
# Related Disease Score Top Affiliating Genes
1 myeloma, multiple 29.4 ALB B2M HGF
2 malignant hypertension 29.1 ADAMTS13 NPPA REN
3 kidney disease 28.5 ALB B2M CST3 NPPA REN
4 acute kidney tubular necrosis 27.6 ALB CST3 HGF IL18 MB NPPA
5 kidney cortex necrosis 11.0
6 phosphoribosylpyrophosphate synthetase superactivity 10.9
7 korean hemorrhagic fever 10.9
8 hemolytic-uremic syndrome 10.9
9 mercury poisoning 10.8 B2M IL18
10 tricuspid valve prolapse 10.7 EGF PIK3C2A
11 virus associated hemophagocytic syndrome 10.7 MB PIK3C2A
12 interstitial myocarditis 10.7 MB PIK3C2A
13 immunodeficiency 43 10.7 ALB B2M
14 metabolic encephalomyopathic crises, recurrent, with rhabdomyolysis, cardiac arrhythmias, and neurodegeneration 10.6 MB PIK3C2A
15 creatine phosphokinase, elevated serum 10.6 MB PIK3C2A
16 posterior myocardial infarction 10.6 MB PIK3C2A
17 burns 10.5 ALB HGF
18 diffuse glomerulonephritis 10.5 ALB B2M
19 myositis fibrosa 10.5 MB PIK3C2A
20 anteroseptal myocardial infarction 10.5 ALB PIK3C2A
21 non-secretory myeloma 10.5 ALB B2M
22 hypoaldosteronism 10.5 NPPA REN
23 gas gangrene 10.5 MB PIK3C2A
24 postural hypotension 10.5 NPPA REN
25 renal artery disease 10.5 NPPA REN
26 hypertension, diastolic 10.4 NPPA REN
27 syndrome of inappropriate antidiuretic hormone 10.4 ALB NPPA
28 hydronephrosis 10.4 ALB B2M EGF
29 benign essential hypertension 10.3 ALB REN
30 acute myocardial infarction 10.3 MB NPPA PIK3C2A
31 kidney papillary necrosis 10.3 ALB REN
32 renal tuberculosis 10.3 B2M REN
33 pyelitis 10.3 B2M REN
34 pericardial effusion 10.3 NPPA PIK3C2A REN
35 compartment syndrome 10.3 ALB MB PIK3C2A
36 noma 10.2 ALB IL18
37 neuroleptic malignant syndrome 10.2 MB PIK3C2A
38 congestive heart failure 10.2 NPPA PIK3C2A REN
39 hennekam syndrome 10.2 ALB EGF
40 pseudohyperkalemia, familial, 2, due to red cell leak 10.1 MB PIK3C2A REN
41 orthostatic proteinuria 10.1 ALB B2M REN
42 diffuse meningeal melanocytosis 10.1 HGF TYR
43 plexopathy 10.1 MB PIK3C2A
44 thrombotic thrombocytopenic purpura, congenital 10.0 ADAMTS13 CFH
45 obstructive jaundice 10.0 ALB HGF REN
46 disseminated intravascular coagulation 10.0 ADAMTS13 MB PIK3C2A
47 catastrophic antiphospholipid syndrome 9.9 ADAMTS13 CFH
48 autosomal dominant polycystic kidney disease 9.9 ALB EGF REN
49 homocystinuria due to cystathionine beta-synthase deficiency 9.9 CST3 TYR
50 arteries, anomalies of 9.9 ALB MB REN

Comorbidity relations with Acute Kidney Failure via Phenotypic Disease Network (PDN): (show top 50) (show all 100)


Acquired Thrombocytopenia Active Peptic Ulcer Disease
Acute Cystitis Acute Myocardial Infarction
Acute Pancreatitis Acute Proliferative Glomerulonephritis
Acute Vascular Insufficiency of Intestine Alcoholic Liver Cirrhosis
Alzheimer Disease Aortic Aneurysm
Aortic Valve Disease 1 Bacteremia 2
Benign Renovascular Hypertension Bladder Cancer
Bladder Neck Obstruction Bleeding Disorder, Platelet-Type, 11
Bronchitis Bronchopneumonia
Candidiasis Cardiac Arrest
Cardiogenic Shock Chronic Intestinal Vascular Insufficiency
Chronic Kidney Failure Chronic Myocardial Ischemia
Chronic Rapidly Progressive Glomerulonephritis Colorectal Cancer
Cystitis Decubitus Ulcer
Deficiency Anemia Dermatomycosis
Diabetic Polyneuropathy Disseminated Intravascular Coagulation
Encephalopathy Esophageal Candidiasis
Familial Atrial Fibrillation First-Degree Atrioventricular Block
Generalized Atherosclerosis Goodpasture Syndrome
Gout Heart Disease
Hemolytic-Uremic Syndrome Hepatic Encephalopathy
Hepatitis Hepatorenal Syndrome
Hydronephrosis Hypertension, Essential
Hypertensive Encephalopathy Hyperuricemia, Pulmonary Hypertension, Renal Failure, and Alkalosis Syndrome
Hypoglycemia Hypoglycemic Coma

Graphical network of the top 20 diseases related to Acute Kidney Failure:



Diseases related to Acute Kidney Failure

Symptoms & Phenotypes for Acute Kidney Failure

MGI Mouse Phenotypes related to Acute Kidney Failure:

46
# Description MGI Source Accession Score Top Affiliating Genes
1 cardiovascular system MP:0005385 10.11 B2M CFH CST3 HGF IL18 MB
2 homeostasis/metabolism MP:0005376 10.03 CST3 IL18 MB NPPA PIK3C2A REN
3 hematopoietic system MP:0005397 10.02 REN SLC22A12 ADAMTS13 B2M CFH HGF
4 mortality/aging MP:0010768 9.93 ADAMTS13 ALB B2M CFH CST3 HGF
5 muscle MP:0005369 9.43 ALB CST3 IL18 MB NPPA REN
6 renal/urinary system MP:0005367 9.17 ALB CFH NPPA PIK3C2A REN SLC22A12

Drugs & Therapeutics for Acute Kidney Failure

Drugs for Acute Kidney Failure (from DrugBank, HMDB, Dgidb, PharmGKB, IUPHAR, NovoSeek, BitterDB):

(show top 50) (show all 671)
# Name Status Phase Clinical Trials Cas Number PubChem Id
1
Dopamine Approved Phase 4,Phase 3,Phase 2,Not Applicable 51-61-6, 62-31-7 681
2
Fenoldopam Approved Phase 4,Phase 3,Phase 2 67227-56-9, 67227-57-0 3341
3
Desflurane Approved Phase 4,Not Applicable 57041-67-5 42113
4
Isoflurane Approved, Vet_approved Phase 4,Phase 3,Not Applicable 26675-46-7 3763
5
Sevoflurane Approved, Vet_approved Phase 4,Phase 3,Phase 2,Phase 1,Not Applicable 28523-86-6 5206
6
Pirfenidone Approved, Investigational Phase 4 53179-13-8 40632
7
Dexmedetomidine Approved, Vet_approved Phase 4,Phase 2,Phase 3,Not Applicable 113775-47-6 68602 5311068
8
Heparin Approved, Investigational Phase 4,Phase 3,Phase 2,Not Applicable 9005-49-6 772 46507594
9
Alprostadil Approved, Investigational Phase 4 745-65-3 149351 5280723
10
Everolimus Approved Phase 4,Phase 3,Phase 2,Not Applicable 159351-69-6 6442177
11
Miconazole Approved, Investigational, Vet_approved Phase 4,Phase 3,Phase 2,Not Applicable 22916-47-8 4189
12
Mycophenolate mofetil Approved, Investigational Phase 4,Phase 3,Phase 1,Phase 2,Not Applicable 128794-94-5 5281078
13
Mycophenolic acid Approved Phase 4,Phase 3,Phase 1,Phase 2,Not Applicable 24280-93-1 446541
14
Prednisone Approved, Vet_approved Phase 4,Phase 2,Phase 3,Phase 1,Not Applicable 53-03-2 5865
15
Sirolimus Approved, Investigational Phase 4,Phase 3,Phase 2,Not Applicable 53123-88-9 5284616 6436030 46835353
16
Tacrolimus Approved, Investigational Phase 4,Phase 3,Phase 1,Phase 2,Not Applicable 104987-11-3 445643 439492
17
Methylprednisolone Approved, Vet_approved Phase 4,Phase 3,Phase 2 83-43-2 6741
18
Prednisolone Approved, Vet_approved Phase 4,Phase 3,Phase 2 50-24-8 5755
19
Insulin Glargine Approved Phase 4 160337-95-1
20
Insulin Lispro Approved Phase 4,Phase 2,Phase 3 133107-64-9
21
Metformin Approved Phase 4 657-24-9 14219 4091
22
Zinc Approved, Investigational Phase 4,Phase 3,Phase 2,Not Applicable 7440-66-6 23994
23
Acetaminophen Approved Phase 4,Phase 3,Phase 2,Not Applicable 103-90-2 1983
24
Clonidine Approved Phase 4,Phase 3 4205-90-7 2803
25 Nefopam Approved, Investigational Phase 4 13669-70-0
26
Ropivacaine Approved Phase 4,Phase 3,Not Applicable 84057-95-4 71273 175805
27
Sufentanil Approved, Investigational Phase 4,Not Applicable 56030-54-7 41693
28
Tramadol Approved, Investigational Phase 4 27203-92-5 33741
29
Acyclovir Approved Phase 4,Phase 2 59277-89-3 2022
30
Ganciclovir Approved, Investigational Phase 4 82410-32-0 3454
31
Etomidate Approved Phase 4,Not Applicable 33125-97-2 36339 667484
32
Midazolam Approved, Illicit Phase 4,Not Applicable 59467-70-8 4192
33
Propofol Approved, Investigational, Vet_approved Phase 4,Phase 3,Phase 1,Not Applicable 2078-54-8 4943
34
Rocuronium Approved Phase 4,Not Applicable 119302-91-9, 143558-00-3 441290
35
Acetylcysteine Approved, Investigational Phase 4,Phase 3,Phase 2,Phase 1,Not Applicable 616-91-1 12035
36
Benzocaine Approved, Investigational Phase 4,Phase 3,Phase 2,Not Applicable 1994-09-7, 94-09-7 2337
37
Nafamostat Approved, Investigational Phase 4,Phase 3 81525-10-2
38
Dalteparin Approved Phase 4,Phase 3 9005-49-6
39
Colistin Approved Phase 4,Phase 3,Not Applicable 1264-72-8, 1066-17-7 5311054
40
Daptomycin Approved, Investigational Phase 4,Phase 3,Not Applicable 103060-53-3 16129629
41
Furosemide Approved, Vet_approved Phase 4,Phase 3,Phase 2,Not Applicable,Early Phase 1 54-31-9 3440
42
Remifentanil Approved Phase 4,Not Applicable 132875-61-7 60815
43
Angiotensin II Approved, Investigational Phase 4,Phase 3,Phase 2 68521-88-0, 4474-91-3, 11128-99-7 172198 65143
44
Nitric Oxide Approved Phase 4,Phase 3,Phase 1,Phase 2 10102-43-9 145068 160954
45
Iron Approved Phase 4,Phase 3,Phase 2,Not Applicable 7439-89-6 23925
46
Norepinephrine Approved Phase 4,Phase 3,Phase 2,Phase 1,Not Applicable 51-41-2 439260
47
Cisplatin Approved Phase 4,Phase 2,Phase 3,Phase 1 15663-27-1 84093 441203 2767
48
Dobutamine Approved Phase 4,Phase 3,Phase 2,Not Applicable 34368-04-2 36811
49
Milrinone Approved Phase 4,Phase 2,Not Applicable 78415-72-2 4197
50
Vancomycin Approved Phase 4,Phase 3,Phase 1,Not Applicable 1404-90-6 441141 14969

Interventional clinical trials:

(show top 50) (show all 1375)
# Name Status NCT ID Phase Drugs
1 Fenoldopam for Prevention of Acute Kidney Injury Unknown status NCT01690832 Phase 4 standard saline infusion;fenoldopam infusion
2 Anesthetic Agents and Acute Kidney Injury After Liver Resection Surgery Unknown status NCT02174575 Phase 4 Sevoflurane;Desflurane
3 Pirfenidone Effect on the Recovery of Renal Function in Septic Acute Kidney Injury Unknown status NCT02530359 Phase 4 Pirfenidone extended release;Placebo equivalent
4 Nutritional Therapy to Prevent Progression of Acute Kidney Injury to Chronic Kidney Disease Unknown status NCT02831062 Phase 4
5 Short-Term Alpha Lipoic Acid Therapy for Prevention of Contrast-induced Acute Kidney Injury and Endothelial Dysfunction in Type 2 Diabetes Unknown status NCT01978405 Phase 4 Alpha lipoic acid
6 Early Continuous Renal Replacement Therapies (CRRT) in Patients With Severe Sepsis or Septic Shock With Acute Kidney Injury Unknown status NCT00837057 Phase 4
7 The Effects of Dexmedetomidine on Postoperative Renal Function in Valvular Heart Surgery Unknown status NCT01886079 Phase 4 dexmedetomidine;Saline
8 Minimizing Contrast Utilization With IVUS Guidance in Coronary Angioplasty to Avoid Acute Nephropathy Unknown status NCT02743156 Phase 4
9 The Effect of Sodium Bicarbonate on Postoperative Renal Function in Infective Endocarditis Patients Undergoing Open Heart Surgery Unknown status NCT01920126 Phase 4 sodium bicarbonate;Saline
10 Limiting IV Chloride to Reduce AKI After Cardiac Surgery Unknown status NCT02020538 Phase 4
11 Citrate Versus Heparin for the Lock of Non-tunneled Hemodialysis Catheters in Patients Hospitalised in ICU Unknown status NCT01962116 Phase 4 Citrate 4%;unfractionated heparin
12 Comparison of Slow Efficiency Daily Dialysis (SLEDD) With Unfractionated Heparin Versus Citrasate in Critically Ill Patients. Unknown status NCT01228292 Phase 4 Unfractionated heparin;Citrasate
13 Efficacy and Safety of Alprostadil Prevent Contrast Induced Nephropathy Unknown status NCT01722513 Phase 4 Alprostadil ﹠control
14 Protective Effects of Oral L-Arginine CI-AKI Unknown status NCT02455960 Phase 4
15 Efficacy and Safety of Heparin-coated Surface-treated Polyacrylonitrile Membrane Hemofilter in Critical Ill CRRT Patients Unknown status NCT02355873 Phase 4
16 Cytokines Evaluation in Early Calcineurin Inhibitors Withdrawn on Renal Transplant Unknown status NCT01239472 Phase 4 everolimus
17 Steroids In caRdiac Surgery Trial (SIRS Trial) Unknown status NCT00427388 Phase 4 Methylprednisolone
18 Abrogation of Mitral Regurgitation Using the MitraClip System in High-Risk Patients Unsuitable for Surgery Unknown status NCT01431222 Phase 4
19 Metformin and Sitagliptin Therapy for Adult Patients With Type 2 Diabetes Admitted to the General Medical Unit Unknown status NCT02250794 Phase 4 metformin and sitagliptin;insulin glargine and insulin lispro;metformin and sitagliptin;insulin glargine and insulin lispro
20 Epidural Analgesia for Pancreatitis (Epipan Study) Unknown status NCT02126332 Phase 4
21 The Pacing vs No Pacing Study - PNP Study Unknown status NCT02498639 Phase 4
22 PTH - Preemptive Treatment for Herpesviridae Unknown status NCT02152358 Phase 4 Aciclovir;Ganciclovir;Placebo
23 Target Controlled Infusion of Etomidate or Propofol for Anesthesia of Thoracoscopic Mitral Valve Replacement Surgery Unknown status NCT02644980 Phase 4 Propofol;Etomidate;Induction of anesthesia;Maintenance of anesthesia
24 Effect of the Intensity of Continuous Renal Replacement Therapy in Patients With Acute Kidney Injury Completed NCT01560650 Phase 4
25 Effect of N-acetylcysteine on Prevention of Acute Kidney Injury in High Risk Patients Undergoing Off-pump Coronary Artery Bypass Graft Completed NCT01394419 Phase 4 N-acetylcysteine;Saline
26 Augmented Vs. Normal Renal Replacement Therapy in Severe Acute Renal Failure (ARF). Completed NCT00221013 Phase 4
27 Metabolic Pattern of Cyclosporine A and Acute Renal Failure Completed NCT00264355 Phase 4 cyclosporine A
28 The Effect of Atorvastatin on Prevention of Postoperative Acute Kidney Injury in Patients Undergoing Aortic Surgery Completed NCT02157337 Phase 4 Atorvastatin;placebo
29 Personalized Versus Standard Hydration for Prevention of CI-AKI: a Randomized Trial With Bioimpedance Analysis Completed NCT02225431 Phase 4 sodium chloride infusion
30 Atorvastatin Versus Rosuvastatin on Contrast Induced Acute Kidney Injury (PRATO-ACS 2) Completed NCT01870804 Phase 4 Rosuvastatin;Atorvastatin
31 The Optimal Mode of Renal Replacement Therapy in Acute Kidney Injury (OMAKI) Study Completed NCT00675818 Phase 4
32 Aminophylline and Contrast Induced Nephropathy in Acute Myocardial Infarction Completed NCT01594489 Phase 4 Aminophylline;Hydration plus N-acetylcisteine
33 Hannover Dialysis Outcome Study Completed NCT00529139 Phase 4
34 Prostacyclin's Effect on Platelet Responsiveness Completed NCT00890214 Phase 4 prostacyclin;heparin
35 Prevention of Acute Kidney Injury by Erythropoietin in Thoracic Aorta Surgery With Hypothermic Cardiac Arrest Completed NCT01369732 Phase 4 recombinant human erythropoietin;saline
36 Rosuvastatin Prevent Contrast Induced Acute Kidney Injury in Patients With Diabetes Completed NCT00786136 Phase 4 rosuvastatin
37 Efficacy of RIPC to Reduce AKI for Patients Undergoing PCI Completed NCT02195726 Phase 4
38 Early Hydration in Acute Myocardial Infarction Completed NCT01742130 Phase 4 sodium bicarbonate solution;Isotonic saline
39 Citrate-based Regional Anticoagulation Versus Heparin for Continuous Renal Replacement Therapy Completed NCT01269112 Phase 4
40 Perioperative Evaluation of Terlipressin Infusion During Living Donor Liver Transplantation on Incidence of Acute Kidney Completed NCT02059460 Phase 4 Terlipressin;placebo
41 Effect of Intraoperative Dexmedetomidine on Development of Acute Kidney Injury Completed NCT02641938 Phase 4 Dexmedetomidine;Normal Saline
42 Trial to Assess the Efficacy and Safety of Nafamostat Mesilate During Continuous Renal Replacement Therapy Completed NCT02478242 Phase 4 Nafamostat mesilate;Normal saline
43 A Comparison of Propofol Based Total Intravenous Anesthesia and Sevoflurane Based Balanced Anesthesia on Renal Protection During Lung Transplantation Under Extracorporeal Membrane Oxygenation - A Prospective, Randomized Trial Completed NCT02009280 Phase 4 Administration of anesthesia: Propofol;Administration of anesthesia: Sevoflurane
44 Pharmacokinetics of Ertapenem in Continuous Venovenous Hemodialysis Completed NCT00877370 Phase 4 ertapenem
45 The Effect of Nafamostat Mesilate in Prolonging Filter Patency With Patients on Continuous Renal Replacement Therapy Completed NCT01761994 Phase 4 Anticoagulation with nafamostat mesilate
46 Nadroparin Anticoagulation for Continuous Venovenous Hemofiltration Completed NCT00965328 Phase 4
47 Biological and Clinical Measurements Following Systemic Leakage When a Citrate or Heparin Lock is Used Completed NCT02860299 Phase 4 citrate 4%;unfractionated heparin
48 CUstodiol Versus RInger: whaT Is the Best Agent? Completed NCT02327611 Phase 4 Custodiol;Enriched Ringer's lactate solution
49 IVUS Guidance to Reduce Contrast in Coronary Angioplasty Completed NCT01947335 Phase 4
50 Everolimus in de Novo Heart Transplant Recipients Completed NCT01017029 Phase 4 Everolimus;Mycophenolate mofetil + Everolimus

Search NIH Clinical Center for Acute Kidney Failure

Inferred drug relations via UMLS 73 / NDF-RT 51 :


Cell-based therapeutics:


LifeMap Discovery
Data from LifeMap, the Embryonic Development and Stem Cells Database
Read about Acute Kidney Failure cell therapies at LifeMap Discovery.

Genetic Tests for Acute Kidney Failure

Anatomical Context for Acute Kidney Failure

MalaCards organs/tissues related to Acute Kidney Failure:

41
Kidney, Heart, Liver, Neutrophil, Endothelial, Testes, Lung
LifeMap Discovery
Data from LifeMap, the Embryonic Development and Stem Cells Database

Cells/anatomical compartments in embryo or adult related to Acute Kidney Failure:
# Tissue Anatomical CompartmentCell Relevance
1 Bone Bone Marrow Bone Marrow Stromal Cells Potential therapeutic candidate
2 Adipose Subcutaneous White Adipose Mesenchymal Stem Cells Potential therapeutic candidate
3 Kidney Proximal Tubule Proximal Tubule Cells Potential therapeutic candidate, affected by disease

Publications for Acute Kidney Failure

Articles related to Acute Kidney Failure:

(show all 50)
# Title Authors Year
1
Acute kidney failure due to polyarteritis nodosa. ( 27939915 )
2017
2
Necroptosis and ferroptosis are alternative cell death pathways that operate in acute kidney failure. ( 28551825 )
2017
3
Pemetrexed-induced acute kidney failure following irreversible renal damage: two case reports and literature review. ( 28491851 )
2017
4
Clinical case report: a rare cause of acute kidney failure - tissue is the issue. ( 27253186 )
2016
5
Proliferative C4 Dense Deposit Disease, Acute ThromboticA Microangiopathy, a Monoclonal Gammopathy, andA Acute Kidney Failure. ( 26704376 )
2016
6
Hyperkalemia and acute kidney failure associated with preoperative uterine artery embolization for a large uterine fibroid: a case report. ( 27799061 )
2016
7
Inhibition of Notch Signaling Ameliorates Acute Kidney Failure and Downregulates Platelet-Derived Growth Factor Receptor I^ in the Mouse Model. ( 26939110 )
2016
8
Acute kidney failure associated with anaphylactic shock caused by diclofenac sodium. ( 25899205 )
2015
9
Elevated biomarkers and contrast-induced acute kidney failure: what comes first the chicken or the egg? ( 25684714 )
2015
10
Older Adults with CKD and Acute Kidney Failure: Do We Know Enough for Critical Shared Decision Making? ( 24262792 )
2014
11
Crohnic kidney disease: recurrent acute kidney failure in a patient with Crohn's disease. ( 25599054 )
2014
12
Novel presentation of rituximab-induced herpes zoster: urinary retention and acute kidney failure. ( 25079963 )
2014
13
Tuberous sclerosis presenting with acute kidney failure, pyelonephritis, and polycystic kidney disease. ( 25001142 )
2014
14
Successful reversal of acute kidney failure by ultrasound-accelerated thrombolysis of an occluded renal artery. ( 25276140 )
2014
15
Joint pain, digital necrosis and acute kidney failure in small-vessel autoimmune disease. ( 26019859 )
2013
16
Acute kidney failure with renal carcinomatous lymphangitis secondary to advanced colon cancer. ( 23903432 )
2013
17
Monitoring of metformin-induced lactic acidosis in a diabetic patient with acute kidney failure and effect of hemodialysis. ( 23149294 )
2013
18
Malignant hypertension with protracted but not definitive oligoanuric acute kidney failure. ( 27293574 )
2013
19
Cardiac catheterization and postoperative acute kidney failure in congenital heart pediatric patients. ( 23780421 )
2013
20
New insights in acute kidney failure in the critically ill. ( 22923149 )
2012
21
Female with rash, acute kidney failure and rheumatoid arthritis. ( 23023360 )
2012
22
Renal Replacement Therapy in Acute Kidney Failure due to Rhabdomyolysis. ( 24826338 )
2012
23
Acute kidney failure complicating carbon monoxide poisoning. ( 22992968 )
2012
24
Primary renal lymphoma: an uncommon diagnosis for acute kidney failure. ( 26019832 )
2012
25
Early biomarkers of acute kidney failure after heart angiography or heart surgery in patients with acute coronary syndrome or acute heart failure. ( 22130209 )
2012
26
Acute kidney failure in the context of a Tako-Tsubo syndrome. ( 21738255 )
2011
27
Renal tubular Fas ligand mediates fratricide in cisplatin-induced acute kidney failure. ( 20811331 )
2011
28
Effective use of continuous arteriovenous hemodialysis in a critically ill human immunodeficiency virus-positive patient with acute kidney failure. ( 20622320 )
2010
29
Hemolysis and acute kidney failure. ( 20605299 )
2010
30
Acute bacterial pyelonephritis resulting in acute kidney failure: a complication of chronic non-steroidal anti-inflammatory drug use? ( 19335847 )
2009
31
Acute kidney failure in neonatal period. ( 19617661 )
2009
32
Acute kidney failure in the third trimester of pregnancy. ( 19008026 )
2009
33
Recurrent acute kidney failure due to McArdle disease. ( 19377243 )
2008
34
RIFLE classification of acute kidney failure in intensive care. ( 17639826 )
2007
35
Focus on hepatitis. Low CD4 count + HCV coinfection = acute kidney failure. ( 17366669 )
2006
36
Summaries for patients. Plasma exchange treatment is not effective in treating acute kidney failure caused by multiple myeloma. ( 16330784 )
2005
37
Postpartum acute kidney failure and hyponatremia: a clinical enigma. ( 15473598 )
2004
38
Acute kidney failure: a pediatric experience over 20 years. ( 12197796 )
2002
39
[Acute kidney failure in the course of rhabdomyolysis with hemodialysis in personal material from 1995-1999]. ( 11255648 )
2000
40
Vasculitis with acute kidney failure and torasemide. ( 9863798 )
1998
41
[Acute kidney failure. Non-invasive diagnosis of acute kidney failure in operative intensive care patients]. ( 9567152 )
1998
42
[Plasma myoglobin and continuous hemofiltration in patients with rhabdomyolysis and acute kidney failure]. ( 9297272 )
1997
43
[Urodilatin (INN: ularitide). A new peptide in the treatment of acute kidney failure following liver transplantation]. ( 8702053 )
1996
44
[Experimental models of acute kidney failure]. ( 7569687 )
1995
45
[Acute kidney failure associated with the HELLP syndrome. A case report]. ( 7959159 )
1994
46
Aggressive peritoneal dialysis for treatment of acute kidney failure after neonatal heart transplantation. ( 1576138 )
1992
47
Hyperosmolar nonketotic syndrome associated with rhabdomyolysis and acute kidney failure. ( 2060421 )
1991
48
Dramatic reduction in sandimmune (CyA) dosage may be effective in reversal of severe hyperbilirubinemia and post-transplant acute kidney failure linked to CyA toxicity. ( 3313989 )
1987
49
Acute kidney failure: prerenal, renal, or postrenal? ( 3932406 )
1985
50
Acute kidney failure. ( 13368869 )
1956

Variations for Acute Kidney Failure

Expression for Acute Kidney Failure

Search GEO for disease gene expression data for Acute Kidney Failure.

Pathways for Acute Kidney Failure

Pathways related to Acute Kidney Failure according to GeneCards Suite gene sharing:

# Super pathways Score Top Affiliating Genes
1 10.92 ALB EGF HGF

GO Terms for Acute Kidney Failure

Cellular components related to Acute Kidney Failure according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 extracellular exosome GO:0070062 9.81 ALB B2M CFH CST3 EGF IL18
2 extracellular region GO:0005576 9.65 ADAMTS13 ALB B2M CFH CST3 EGF
3 endoplasmic reticulum lumen GO:0005788 9.62 ADAMTS13 ALB B2M CST3
4 platelet alpha granule lumen GO:0031093 9.43 ALB EGF HGF
5 extracellular space GO:0005615 9.32 ADAMTS13 ALB B2M CFH CST3 EGF

Biological processes related to Acute Kidney Failure according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 response to hypoxia GO:0001666 9.54 CST3 MB NPPA
2 positive regulation of protein kinase B signaling GO:0051897 9.5 EGF HGF IL18
3 platelet degranulation GO:0002576 9.43 ALB EGF HGF
4 phosphatidylinositol phosphorylation GO:0046854 9.33 EGF HGF PIK3C2A
5 response to drug GO:0042493 9.26 B2M CST3 REN SLC22A12
6 cellular protein metabolic process GO:0044267 8.92 ALB B2M CST3 NPPA

Sources for Acute Kidney Failure

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
17 ExPASy
19 FMA
28 GO
29 GTR
30 HGMD
31 HMDB
32 HPO
33 ICD10
34 ICD10 via Orphanet
35 ICD9CM
36 IUPHAR
37 KEGG
38 LifeMap
40 LOVD
42 MedGen
44 MeSH
45 MESH via Orphanet
46 MGI
49 NCI
50 NCIt
51 NDF-RT
54 NINDS
55 Novoseek
57 OMIM
58 OMIM via Orphanet
62 PubMed
64 QIAGEN
69 SNOMED-CT via HPO
70 SNOMED-CT via Orphanet
71 TGDB
72 Tocris
73 UMLS
74 UMLS via Orphanet
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