MCID: ACT071
MIFTS: 51

Acute Kidney Failure

Categories: Blood diseases, Bone diseases, Genetic diseases, Nephrological diseases

Aliases & Classifications for Acute Kidney Failure

MalaCards integrated aliases for Acute Kidney Failure:

Name: Acute Kidney Failure 38 12 15
Pre-Renal Acute Kidney Injury 73
Kidney Failure, Acute 73
Acute Renal Failure 76
Renal Failure Acute 55
Acute Kidney Injury 44

Classifications:



External Ids:

Disease Ontology 12 DOID:3021
MeSH 44 D058186
ICD10 33 N17 N17.1 N17.2

Summaries for Acute Kidney Failure

MalaCards based summary : Acute Kidney Failure, also known as pre-renal acute kidney injury, is related to hepatorenal syndrome and metabolic encephalomyopathic crises, recurrent, with rhabdomyolysis, cardiac arrhythmias, and neurodegeneration. An important gene associated with Acute Kidney Failure is MGAT3-AS1 (MGAT3 Antisense RNA 1), and among its related pathways/superpathways is Embryonic and Induced Pluripotent Stem Cell Differentiation Pathways and Lineage-specific Markers. The drugs Dopamine and Fenoldopam have been mentioned in the context of this disorder. Affiliated tissues include Bone and Adipose, and related phenotypes are cardiovascular system and homeostasis/metabolism

Wikipedia : 76 Acute kidney injury (AKI), previously called acute renal failure (ARF), is an abrupt loss of kidney... more...

Related Diseases for Acute Kidney Failure

Diseases in the Kidney Disease family:

Acute Kidney Failure Chronic Kidney Failure
Renal Infectious Disease Ren-Related Kidney Disease

Diseases related to Acute Kidney Failure via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50) (show all 669)
# Related Disease Score Top Affiliating Genes
1 hepatorenal syndrome 31.1 ALB CST3 IL18 NPPA REN
2 metabolic encephalomyopathic crises, recurrent, with rhabdomyolysis, cardiac arrhythmias, and neurodegeneration 30.8 MB PIK3C2A
3 acute kidney tubular necrosis 30.4 ALB B2M CST3 HGF IL18 MB
4 anuria 30.3 ALB MB PIK3C2A REN
5 neuroleptic malignant syndrome 30.3 MB PIK3C2A
6 disseminated intravascular coagulation 30.2 ADAMTS13 MB PIK3C2A
7 compartment syndrome 30.2 ALB MB PIK3C2A
8 pericardial effusion 30.2 NPPA PIK3C2A REN
9 urinary tract obstruction 30.1 ALB B2M EGF REN
10 hemorrhagic fever 30.0 ALB B2M
11 danubian endemic familial nephropathy 29.9 ALB B2M
12 pulmonary edema 29.9 NPPA PIK3C2A REN
13 gas gangrene 29.9 MB PIK3C2A
14 obstructive nephropathy 29.9 ALB EGF HGF REN
15 mercury poisoning 29.8 B2M IL18
16 obstructive jaundice 29.7 ALB HGF REN
17 coronary artery anomaly 29.7 MB NPPA PIK3C2A
18 hypoaldosteronism 29.7 NPPA REN
19 hydronephrosis 29.6 ALB B2M EGF
20 acute myocardial infarction 29.6 MB NPPA PIK3C2A
21 renal tuberculosis 29.6 B2M REN
22 liver cirrhosis 29.6 ALB HGF NPPA REN
23 arteries, anomalies of 29.5 ALB MB REN
24 thrombotic thrombocytopenic purpura, congenital 29.5 ADAMTS13 CFH
25 malignant hypertension 29.4 ADAMTS13 NPPA REN
26 kidney disease 29.1 ALB B2M CFH CST3 NPPA REN
27 heart disease 29.1 ALB CST3 NPPA PIK3C2A REN
28 chronic kidney failure 28.8 ALB B2M CFH CST3 NPPA REN
29 myocardial infarction 28.6 ADAMTS13 ALB CST3 MB NPPA PIK3C2A
30 hypouricemia, renal, 1 11.6
31 cholera 11.4
32 rapidly progressive glomerulonephritis 11.3
33 hypouricemia, renal, 2 11.2
34 kidney cortex necrosis 11.2
35 glycogen storage disease v 11.0
36 hemolytic uremic syndrome, atypical 1 11.0
37 xanthinuria, type ii 11.0
38 adenine phosphoribosyltransferase deficiency 11.0
39 phosphoribosylpyrophosphate synthetase superactivity 11.0
40 korean hemorrhagic fever 11.0
41 hemolytic-uremic syndrome 11.0
42 interstitial nephritis 10.4
43 myoglobinuria 10.4
44 glomerulonephritis 10.4
45 nephrotic syndrome 10.2
46 purpura 10.2
47 tricuspid valve prolapse 10.2 EGF PIK3C2A
48 hemoglobinuria 10.2
49 virus associated hemophagocytic syndrome 10.2 MB PIK3C2A
50 legionellosis 10.2

Comorbidity relations with Acute Kidney Failure via Phenotypic Disease Network (PDN): (show top 50) (show all 99)


Acquired Thrombocytopenia Active Peptic Ulcer Disease
Acute Cystitis Acute Myocardial Infarction
Acute Pancreatitis Acute Proliferative Glomerulonephritis
Acute Vascular Insufficiency of Intestine Alcoholic Liver Cirrhosis
Alzheimer Disease Aortic Aneurysm
Aortic Valve Disease 1 Bacteremia 2
Benign Renovascular Hypertension Bladder Cancer
Bladder Neck Obstruction Bleeding Disorder, Platelet-Type, 11
Bronchitis Bronchopneumonia
Candidiasis Cardiac Arrest
Cardiogenic Shock Chronic Intestinal Vascular Insufficiency
Chronic Kidney Failure Chronic Myocardial Ischemia
Chronic Rapidly Progressive Glomerulonephritis Colorectal Cancer
Cystitis Decubitus Ulcer
Deficiency Anemia Dermatomycosis
Diabetic Polyneuropathy Disseminated Intravascular Coagulation
Encephalopathy Esophageal Candidiasis
Familial Atrial Fibrillation First-Degree Atrioventricular Block
Generalized Atherosclerosis Goodpasture Syndrome
Gout Heart Disease
Hemolytic-Uremic Syndrome Hepatic Encephalopathy
Hepatitis Hepatorenal Syndrome
Hydronephrosis Hypertension, Essential
Hypertensive Encephalopathy Hyperuricemia, Pulmonary Hypertension, Renal Failure, and Alkalosis Syndrome
Hypoglycemia Hypoglycemic Coma

Graphical network of the top 20 diseases related to Acute Kidney Failure:



Diseases related to Acute Kidney Failure

Symptoms & Phenotypes for Acute Kidney Failure

MGI Mouse Phenotypes related to Acute Kidney Failure:

46
# Description MGI Source Accession Score Top Affiliating Genes
1 cardiovascular system MP:0005385 10.14 B2M CFH CST3 HGF IL18 MB
2 homeostasis/metabolism MP:0005376 10.03 ADAMTS13 ALB B2M CFH CST3 IL18
3 growth/size/body region MP:0005378 10.02 B2M EGF HGF IL18 MB PIK3C2A
4 hematopoietic system MP:0005397 10.02 ADAMTS13 B2M CFH HGF IL18 MB
5 mortality/aging MP:0010768 9.93 ADAMTS13 ALB B2M CFH CST3 HGF
6 muscle MP:0005369 9.43 ALB CST3 IL18 MB NPPA REN
7 renal/urinary system MP:0005367 9.17 ALB CFH NPPA PIK3C2A REN SLC22A12

Drugs & Therapeutics for Acute Kidney Failure

Drugs for Acute Kidney Failure (from DrugBank, HMDB, Dgidb, PharmGKB, IUPHAR, NovoSeek, BitterDB):

(show top 50) (show all 713)
# Name Status Phase Clinical Trials Cas Number PubChem Id
1
Dopamine Approved Phase 4,Phase 3,Phase 2,Not Applicable 51-61-6, 62-31-7 681
2
Fenoldopam Approved Phase 4,Phase 3,Phase 2 67227-57-0, 67227-56-9 3341
3
Isoflurane Approved, Vet_approved Phase 4,Phase 3,Not Applicable 26675-46-7 3763
4
Sevoflurane Approved, Vet_approved Phase 4,Phase 3,Phase 2,Phase 1,Not Applicable 28523-86-6 5206
5
Desflurane Approved Phase 4,Not Applicable 57041-67-5 42113
6
Pirfenidone Approved, Investigational Phase 4 53179-13-8 40632
7
Dexmedetomidine Approved, Vet_approved Phase 4,Phase 2,Phase 3,Not Applicable 113775-47-6 68602 5311068
8
Heparin Approved, Investigational Phase 4,Phase 3,Phase 2,Not Applicable 9005-49-6 772 46507594
9
Alprostadil Approved, Investigational Phase 4 745-65-3 149351 5280723
10
Everolimus Approved Phase 4,Phase 3,Not Applicable 159351-69-6 6442177
11
Prednisone Approved, Vet_approved Phase 4,Phase 2,Phase 3,Phase 1,Not Applicable 53-03-2 5865
12
Mycophenolic acid Approved Phase 4,Phase 3,Phase 1,Phase 2,Not Applicable 24280-93-1 446541
13
Miconazole Approved, Investigational, Vet_approved Phase 4,Phase 3,Phase 2,Not Applicable 22916-47-8 4189
14
Sirolimus Approved, Investigational Phase 4,Phase 3,Phase 2,Not Applicable 53123-88-9 46835353 6436030 5284616
15
Tacrolimus Approved, Investigational Phase 4,Phase 3,Phase 1,Phase 2,Not Applicable 104987-11-3 445643 439492
16
Methylprednisolone Approved, Vet_approved Phase 4,Phase 3,Phase 2,Not Applicable 83-43-2 6741
17
Methylprednisolone hemisuccinate Approved Phase 4,Phase 3,Phase 2,Not Applicable 2921-57-5
18
Prednisolone phosphate Approved, Vet_approved Phase 4,Phase 3,Phase 2,Not Applicable 302-25-0
19
Prednisolone Approved, Vet_approved Phase 4,Phase 3,Phase 2,Not Applicable 50-24-8 5755
20
Zinc Approved, Investigational Phase 4,Phase 3,Phase 2,Not Applicable 7440-66-6
21
Metformin Approved Phase 4 657-24-9 14219 4091
22
Insulin Lispro Approved Phase 4,Phase 2,Phase 3 133107-64-9
23
Insulin Glargine Approved Phase 4 160337-95-1
24
Acetaminophen Approved Phase 4,Phase 3,Phase 2,Not Applicable 103-90-2 1983
25
Clonidine Approved Phase 4,Phase 3 4205-90-7 2803
26 Nefopam Approved, Investigational Phase 4 13669-70-0
27
Sufentanil Approved, Investigational Phase 4,Not Applicable 56030-54-7 41693
28
Ropivacaine Approved Phase 4,Phase 3,Not Applicable 84057-95-4 175805 71273
29
Tramadol Approved, Investigational Phase 4 27203-92-5 33741
30
Acyclovir Approved Phase 4,Phase 2 59277-89-3 2022
31
Ganciclovir Approved, Investigational Phase 4 82410-32-0 3454
32
Midazolam Approved, Illicit Phase 4,Not Applicable 59467-70-8 4192
33
Propofol Approved, Investigational, Vet_approved Phase 4,Phase 3,Phase 1,Not Applicable 2078-54-8 4943
34
Etomidate Approved Phase 4,Not Applicable 33125-97-2 667484 36339
35
Rocuronium Approved Phase 4,Not Applicable 119302-91-9, 143558-00-3 441290
36
Tobramycin Approved, Investigational Phase 4 32986-56-4 36294 5496
37
Vancomycin Approved Phase 4,Phase 3,Phase 1,Not Applicable 1404-90-6 14969 441141
38
Acetylcysteine Approved, Investigational Phase 4,Phase 3,Phase 2,Phase 1,Not Applicable 616-91-1 12035
39
Aminophylline Approved Phase 4,Early Phase 1,Not Applicable 317-34-0 9433
40 tannic acid Approved Phase 4,Phase 3,Phase 2,Not Applicable
41
Benzocaine Approved, Investigational Phase 4,Phase 3,Phase 2,Not Applicable 94-09-7, 1994-09-7 2337
42
Dalteparin Approved Phase 4,Phase 3 9005-49-6
43
Colistin Approved Phase 4,Phase 3,Not Applicable 1264-72-8, 1066-17-7 5311054
44
Daptomycin Approved, Investigational Phase 4,Phase 3,Not Applicable 103060-53-3 16129629
45
Furosemide Approved, Vet_approved Phase 4,Phase 3,Phase 2,Early Phase 1,Not Applicable 54-31-9 3440
46
Remifentanil Approved Phase 4,Not Applicable 132875-61-7 60815
47
Angiotensin II Approved, Investigational Phase 4,Phase 3,Phase 2 11128-99-7, 68521-88-0, 4474-91-3 172198 65143
48
Nitric Oxide Approved Phase 4,Phase 3,Phase 1,Phase 2 10102-43-9 145068
49
Iron Approved Phase 4,Phase 3,Phase 2,Phase 1,Not Applicable 7439-89-6 23925
50
Norepinephrine Approved Phase 4,Phase 3,Phase 2,Phase 1,Not Applicable 51-41-2 439260

Interventional clinical trials:

(show top 50) (show all 1511)
# Name Status NCT ID Phase Drugs
1 Fenoldopam for Prevention of Acute Kidney Injury Unknown status NCT01690832 Phase 4 standard saline infusion;fenoldopam infusion
2 Anesthetic Agents and Acute Kidney Injury After Liver Resection Surgery Unknown status NCT02174575 Phase 4 Sevoflurane;Desflurane
3 Pirfenidone Effect on the Recovery of Renal Function in Septic Acute Kidney Injury Unknown status NCT02530359 Phase 4 Pirfenidone extended release;Placebo equivalent
4 Nutritional Therapy to Prevent Progression of Acute Kidney Injury to Chronic Kidney Disease Unknown status NCT02831062 Phase 4
5 Short-Term Alpha Lipoic Acid Therapy for Prevention of Contrast-induced Acute Kidney Injury and Endothelial Dysfunction in Type 2 Diabetes Unknown status NCT01978405 Phase 4 Alpha lipoic acid
6 Early Continuous Renal Replacement Therapies (CRRT) in Patients With Severe Sepsis or Septic Shock With Acute Kidney Injury Unknown status NCT00837057 Phase 4
7 The Effects of Dexmedetomidine on Postoperative Renal Function in Valvular Heart Surgery Unknown status NCT01886079 Phase 4 dexmedetomidine;Saline
8 Minimizing Contrast Utilization With IVUS Guidance in Coronary Angioplasty to Avoid Acute Nephropathy Unknown status NCT02743156 Phase 4
9 Limiting IV Chloride to Reduce AKI After Cardiac Surgery Unknown status NCT02020538 Phase 4
10 Comparison of Slow Efficiency Daily Dialysis (SLEDD) With Unfractionated Heparin Versus Citrasate in Critically Ill Patients. Unknown status NCT01228292 Phase 4 Unfractionated heparin;Citrasate
11 Efficacy and Safety of Alprostadil Prevent Contrast Induced Nephropathy Unknown status NCT01722513 Phase 4 Alprostadil ﹠control
12 Protective Effects of Oral L-Arginine CI-AKI Unknown status NCT02455960 Phase 4
13 Efficacy and Safety of Heparin-coated Surface-treated Polyacrylonitrile Membrane Hemofilter in Critical Ill CRRT Patients Unknown status NCT02355873 Phase 4
14 Cytokines Evaluation in Early Calcineurin Inhibitors Withdrawn on Renal Transplant Unknown status NCT01239472 Phase 4 everolimus
15 Steroids In caRdiac Surgery Trial (SIRS Trial) Unknown status NCT00427388 Phase 4 Methylprednisolone
16 Abrogation of Mitral Regurgitation Using the MitraClip System in High-Risk Patients Unsuitable for Surgery Unknown status NCT01431222 Phase 4
17 Metformin and Sitagliptin Therapy for Adult Patients With Type 2 Diabetes Admitted to the General Medical Unit Unknown status NCT02250794 Phase 4 metformin and sitagliptin;insulin glargine and insulin lispro;metformin and sitagliptin;insulin glargine and insulin lispro
18 Epidural Analgesia for Pancreatitis (Epipan Study) Unknown status NCT02126332 Phase 4
19 The Pacing vs No Pacing Study - PNP Study Unknown status NCT02498639 Phase 4
20 PTH - Preemptive Treatment for Herpesviridae Unknown status NCT02152358 Phase 4 Aciclovir;Ganciclovir;Placebo
21 The Effect of Branched-chain Amino Acid on the Improvement of Serum Albumin Level in Cirrhotic Patients With Ascites Unknown status NCT02755701 Phase 4 Branched-chain Amino Acid;Placebo
22 Target Controlled Infusion of Etomidate or Propofol for Anesthesia of Thoracoscopic Mitral Valve Replacement Surgery Unknown status NCT02644980 Phase 4 Propofol;Etomidate;Induction of anesthesia;Maintenance of anesthesia
23 Aerosolized Antibiotics in the Treatment of Ventilator Associated Pneumonia Unknown status NCT02478710 Phase 4 Aerosolized Tobramycin or Vancomycin;Aerosolized Placebo
24 Effect of the Intensity of Continuous Renal Replacement Therapy in Patients With Acute Kidney Injury Completed NCT01560650 Phase 4
25 Effect of N-acetylcysteine on Prevention of Acute Kidney Injury in High Risk Patients Undergoing Off-pump Coronary Artery Bypass Graft Completed NCT01394419 Phase 4 N-acetylcysteine;Saline
26 Augmented Vs. Normal Renal Replacement Therapy in Severe Acute Renal Failure (ARF). Completed NCT00221013 Phase 4
27 Metabolic Pattern of Cyclosporine A and Acute Renal Failure Completed NCT00264355 Phase 4 cyclosporine A
28 The Effect of Atorvastatin on Prevention of Postoperative Acute Kidney Injury in Patients Undergoing Aortic Surgery Completed NCT02157337 Phase 4 Atorvastatin;placebo
29 Personalized Versus Standard Hydration for Prevention of CI-AKI: a Randomized Trial With Bioimpedance Analysis Completed NCT02225431 Phase 4 sodium chloride infusion
30 Atorvastatin Versus Rosuvastatin on Contrast Induced Acute Kidney Injury (PRATO-ACS 2) Completed NCT01870804 Phase 4 Rosuvastatin;Atorvastatin
31 The Optimal Mode of Renal Replacement Therapy in Acute Kidney Injury (OMAKI) Study Completed NCT00675818 Phase 4
32 Aminophylline and Contrast Induced Nephropathy in Acute Myocardial Infarction Completed NCT01594489 Phase 4 Aminophylline;Hydration plus N-acetylcisteine
33 Hannover Dialysis Outcome Study Completed NCT00529139 Phase 4
34 Prostacyclin's Effect on Platelet Responsiveness Completed NCT00890214 Phase 4 prostacyclin;heparin
35 Prevention of Acute Kidney Injury by Erythropoietin in Thoracic Aorta Surgery With Hypothermic Cardiac Arrest Completed NCT01369732 Phase 4 recombinant human erythropoietin;saline
36 Rosuvastatin Prevent Contrast Induced Acute Kidney Injury in Patients With Diabetes Completed NCT00786136 Phase 4 rosuvastatin
37 Early Hydration in Acute Myocardial Infarction Completed NCT01742130 Phase 4 sodium bicarbonate solution;Isotonic saline
38 Efficacy of RIPC to Reduce AKI for Patients Undergoing PCI Completed NCT02195726 Phase 4
39 Citrate-based Regional Anticoagulation Versus Heparin for Continuous Renal Replacement Therapy Completed NCT01269112 Phase 4
40 Perioperative Evaluation of Terlipressin Infusion During Living Donor Liver Transplantation on Incidence of Acute Kidney Completed NCT02059460 Phase 4 Terlipressin;placebo
41 The Effect of Sodium Bicarbonate on Postoperative Renal Function in Infective Endocarditis Patients Undergoing Open Heart Surgery Completed NCT01920126 Phase 4 sodium bicarbonate;Saline
42 Effect of Intraoperative Dexmedetomidine on Development of Acute Kidney Injury Completed NCT02641938 Phase 4 Dexmedetomidine;Normal Saline
43 Trial to Assess the Efficacy and Safety of Nafamostat Mesilate During Continuous Renal Replacement Therapy Completed NCT02478242 Phase 4 Nafamostat mesilate;Normal saline
44 A Comparison of Propofol Based Total Intravenous Anesthesia and Sevoflurane Based Balanced Anesthesia on Renal Protection During Lung Transplantation Under Extracorporeal Membrane Oxygenation - A Prospective, Randomized Trial Completed NCT02009280 Phase 4 Administration of anesthesia: Propofol;Administration of anesthesia: Sevoflurane
45 Pharmacokinetics of Ertapenem in Continuous Venovenous Hemodialysis Completed NCT00877370 Phase 4 ertapenem
46 The Effect of Nafamostat Mesilate in Prolonging Filter Patency With Patients on Continuous Renal Replacement Therapy Completed NCT01761994 Phase 4 Anticoagulation with nafamostat mesilate
47 Nadroparin Anticoagulation for Continuous Venovenous Hemofiltration Completed NCT00965328 Phase 4
48 Biological and Clinical Measurements Following Systemic Leakage When a Citrate or Heparin Lock is Used Completed NCT02860299 Phase 4 citrate 4%;unfractionated heparin
49 CUstodiol Versus RInger: whaT Is the Best Agent? Completed NCT02327611 Phase 4 Custodiol;Enriched Ringer's lactate solution
50 IVUS Guidance to Reduce Contrast in Coronary Angioplasty Completed NCT01947335 Phase 4

Search NIH Clinical Center for Acute Kidney Failure

Inferred drug relations via UMLS 73 / NDF-RT 51 :


Cell-based therapeutics:


LifeMap Discovery
Data from LifeMap, the Embryonic Development and Stem Cells Database
Read about Acute Kidney Failure cell therapies at LifeMap Discovery.

Cochrane evidence based reviews: acute kidney injury

Genetic Tests for Acute Kidney Failure

Anatomical Context for Acute Kidney Failure

MalaCards organs/tissues related to Acute Kidney Failure:

41
Kidney, Bone, Bone Marrow, Brain, Heart, Liver, Lung
LifeMap Discovery
Data from LifeMap, the Embryonic Development and Stem Cells Database

Cells/anatomical compartments in embryo or adult related to Acute Kidney Failure:
# Tissue Anatomical CompartmentCell Relevance
1 Bone Bone Marrow Bone Marrow Stromal Cells Potential therapeutic candidate
2 Adipose Subcutaneous White Adipose Mesenchymal Stem Cells Potential therapeutic candidate
3 Kidney Proximal Tubule Proximal Tubule Cells Affected by disease, potential therapeutic candidate

Publications for Acute Kidney Failure

Articles related to Acute Kidney Failure:

(show top 50) (show all 56)
# Title Authors Year
1
Acute Kidney Failure as a Single Complication of Varicella Virus Infection in an Adult Patient. ( 30197901 )
2018
2
Acute kidney failure due to polyarteritis nodosa. ( 27939915 )
2017
3
Necroptosis and ferroptosis are alternative cell death pathways that operate in acute kidney failure. ( 28551825 )
2017
4
Pemetrexed-induced acute kidney failure following irreversible renal damage: two case reports and literature review. ( 28491851 )
2017
5
Clinical case report: a rare cause of acute kidney failure - tissue is the issue. ( 27253186 )
2016
6
Proliferative C4 Dense Deposit Disease, Acute ThromboticA Microangiopathy, a Monoclonal Gammopathy, andA Acute Kidney Failure. ( 26704376 )
2016
7
Hyperkalemia and acute kidney failure associated with preoperative uterine artery embolization for a large uterine fibroid: a case report. ( 27799061 )
2016
8
Inhibition of Notch Signaling Ameliorates Acute Kidney Failure and Downregulates Platelet-Derived Growth Factor Receptor I^ in the Mouse Model. ( 26939110 )
2016
9
Clinical Scenarios in Acute Kidney Injury: Pre-Renal Acute Kidney Injury. ( 27169621 )
2016
10
Acute kidney failure associated with anaphylactic shock caused by diclofenac sodium. ( 25899205 )
2015
11
Elevated biomarkers and contrast-induced acute kidney failure: what comes first the chicken or the egg? ( 25684714 )
2015
12
Older Adults with CKD and Acute Kidney Failure: Do We Know Enough for Critical Shared Decision Making? ( 24262792 )
2014
13
Crohnic kidney disease: recurrent acute kidney failure in a patient with Crohn's disease. ( 25599054 )
2014
14
Novel presentation of rituximab-induced herpes zoster: urinary retention and acute kidney failure. ( 25079963 )
2014
15
Tuberous sclerosis presenting with acute kidney failure, pyelonephritis, and polycystic kidney disease. ( 25001142 )
2014
16
Successful reversal of acute kidney failure by ultrasound-accelerated thrombolysis of an occluded renal artery. ( 25276140 )
2014
17
Joint pain, digital necrosis and acute kidney failure in small-vessel autoimmune disease. ( 26019859 )
2013
18
Acute kidney failure with renal carcinomatous lymphangitis secondary to advanced colon cancer. ( 23903432 )
2013
19
Monitoring of metformin-induced lactic acidosis in a diabetic patient with acute kidney failure and effect of hemodialysis. ( 23149294 )
2013
20
Malignant hypertension with protracted but not definitive oligoanuric acute kidney failure. ( 27293574 )
2013
21
Cardiac catheterization and postoperative acute kidney failure in congenital heart pediatric patients. ( 23780421 )
2013
22
The case: fever, myalgia, visual disorders, and acute kidney failure in a pregnant woman. Diagnosis: Severe acute hantavirus infection. ( 23989371 )
2013
23
Urinalysis and pre-renal acute kidney injury: time to move on. ( 23659200 )
2013
24
New insights in acute kidney failure in the critically ill. ( 22923149 )
2012
25
Female with rash, acute kidney failure and rheumatoid arthritis. ( 23023360 )
2012
26
Renal Replacement Therapy in Acute Kidney Failure due to Rhabdomyolysis. ( 24826338 )
2012
27
Acute kidney failure complicating carbon monoxide poisoning. ( 22992968 )
2012
28
Primary renal lymphoma: an uncommon diagnosis for acute kidney failure. ( 26019832 )
2012
29
Early biomarkers of acute kidney failure after heart angiography or heart surgery in patients with acute coronary syndrome or acute heart failure. ( 22130209 )
2012
30
Acute kidney failure in the context of a Tako-Tsubo syndrome. ( 21738255 )
2011
31
Renal tubular Fas ligand mediates fratricide in cisplatin-induced acute kidney failure. ( 20811331 )
2011
32
Effective use of continuous arteriovenous hemodialysis in a critically ill human immunodeficiency virus-positive patient with acute kidney failure. ( 20622320 )
2010
33
Hemolysis and acute kidney failure. ( 20605299 )
2010
34
Acute tubular necrosis and pre-renal acute kidney injury: utility of urine microscopy in their evaluation- a systematic review. ( 19921458 )
2010
35
Acute bacterial pyelonephritis resulting in acute kidney failure: a complication of chronic non-steroidal anti-inflammatory drug use? ( 19335847 )
2009
36
Acute kidney failure in neonatal period. ( 19617661 )
2009
37
Acute kidney failure in the third trimester of pregnancy. ( 19008026 )
2009
38
Acute kidney failure and an epigastric mass. ( 25949294 )
2009
39
Recurrent acute kidney failure due to McArdle disease. ( 19377243 )
2008
40
RIFLE classification of acute kidney failure in intensive care. ( 17639826 )
2007
41
Focus on hepatitis. Low CD4 count + HCV coinfection = acute kidney failure. ( 17366669 )
2006
42
Summaries for patients. Plasma exchange treatment is not effective in treating acute kidney failure caused by multiple myeloma. ( 16330784 )
2005
43
Postpartum acute kidney failure and hyponatremia: a clinical enigma. ( 15473598 )
2004
44
Acute kidney failure: a pediatric experience over 20 years. ( 12197796 )
2002
45
[Acute kidney failure in the course of rhabdomyolysis with hemodialysis in personal material from 1995-1999]. ( 11255648 )
2000
46
Vasculitis with acute kidney failure and torasemide. ( 9863798 )
1998
47
[Acute kidney failure. Non-invasive diagnosis of acute kidney failure in operative intensive care patients]. ( 9567152 )
1998
48
[Plasma myoglobin and continuous hemofiltration in patients with rhabdomyolysis and acute kidney failure]. ( 9297272 )
1997
49
[Urodilatin (INN: ularitide). A new peptide in the treatment of acute kidney failure following liver transplantation]. ( 8702053 )
1996
50
[Experimental models of acute kidney failure]. ( 7569687 )
1995

Variations for Acute Kidney Failure

Expression for Acute Kidney Failure

Search GEO for disease gene expression data for Acute Kidney Failure.

Pathways for Acute Kidney Failure

Pathways related to Acute Kidney Failure according to GeneCards Suite gene sharing:

# Super pathways Score Top Affiliating Genes
1 10.92 ALB EGF HGF

GO Terms for Acute Kidney Failure

Cellular components related to Acute Kidney Failure according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 extracellular exosome GO:0070062 9.86 ALB B2M CFH CST3 EGF MB
2 extracellular region GO:0005576 9.65 ADAMTS13 ALB B2M CFH CST3 EGF
3 endoplasmic reticulum lumen GO:0005788 9.62 ADAMTS13 ALB B2M CST3
4 platelet alpha granule lumen GO:0031093 9.33 ALB EGF HGF
5 extracellular space GO:0005615 9.32 ADAMTS13 ALB B2M CFH CST3 EGF

Biological processes related to Acute Kidney Failure according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 positive regulation of protein kinase B signaling GO:0051897 9.43 EGF HGF IL18
2 platelet degranulation GO:0002576 9.33 ALB EGF HGF
3 phosphatidylinositol phosphorylation GO:0046854 9.13 EGF HGF PIK3C2A
4 cellular protein metabolic process GO:0044267 8.92 ALB B2M CST3 NPPA

Sources for Acute Kidney Failure

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
17 ExPASy
19 FMA
28 GO
29 GTR
30 HGMD
31 HMDB
32 HPO
33 ICD10
34 ICD10 via Orphanet
35 ICD9CM
36 IUPHAR
37 KEGG
38 LifeMap
40 LOVD
42 MedGen
44 MeSH
45 MESH via Orphanet
46 MGI
49 NCI
50 NCIt
51 NDF-RT
54 NINDS
55 Novoseek
57 OMIM
58 OMIM via Orphanet
62 PubMed
64 QIAGEN
69 SNOMED-CT via HPO
70 SNOMED-CT via Orphanet
71 TGDB
72 Tocris
73 UMLS
74 UMLS via Orphanet
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