MCID: ACT071
MIFTS: 54

Acute Kidney Failure

Categories: Blood diseases, Bone diseases, Genetic diseases, Nephrological diseases

Aliases & Classifications for Acute Kidney Failure

MalaCards integrated aliases for Acute Kidney Failure:

Name: Acute Kidney Failure 39 12 15
Pre-Renal Acute Kidney Injury 74
Kidney Failure, Acute 74
Acute Renal Failure 77
Renal Failure Acute 56
Acute Kidney Injury 45

Classifications:



External Ids:

Disease Ontology 12 DOID:3021
MeSH 45 D058186
ICD10 34 N17 N17.1 N17.2

Summaries for Acute Kidney Failure

MalaCards based summary : Acute Kidney Failure, also known as pre-renal acute kidney injury, is related to kidney cortex necrosis and hepatorenal syndrome. An important gene associated with Acute Kidney Failure is MGAT3-AS1 (MGAT3 Antisense RNA 1), and among its related pathways/superpathways is Embryonic and Induced Pluripotent Stem Cell Differentiation Pathways and Lineage-specific Markers. The drugs Dopamine and Fenoldopam have been mentioned in the context of this disorder. Affiliated tissues include Bone and Adipose, and related phenotypes are cardiovascular system and homeostasis/metabolism

Wikipedia : 77 Acute kidney injury (AKI), previously called acute renal failure (ARF), is an abrupt loss of kidney... more...

Related Diseases for Acute Kidney Failure

Diseases in the Kidney Disease family:

Acute Kidney Failure Chronic Kidney Failure
Renal Infectious Disease Ren-Related Kidney Disease

Diseases related to Acute Kidney Failure via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50) (show all 775)
# Related Disease Score Top Affiliating Genes
1 kidney cortex necrosis 31.6 GPT TYR
2 hepatorenal syndrome 30.9 ALB CST3 IL18 NPPA REN
3 compartment syndrome 30.6 ALB MB PIK3C2A
4 disseminated intravascular coagulation 30.6 ADAMTS13 MB PIK3C2A
5 burns 30.4 ALB HGF
6 anuria 30.3 ALB MB PIK3C2A REN
7 neuroleptic malignant syndrome 30.3 MB PIK3C2A
8 pericardial effusion 30.3 NPPA PIK3C2A REN
9 gas gangrene 30.2 MB PIK3C2A
10 urinary tract obstruction 30.2 ALB B2M EGF REN
11 acute kidney tubular necrosis 30.2 ALB B2M CST3 HGF IL18 MB
12 al amyloidosis 30.2 B2M CST3
13 pulmonary edema 30.1 NPPA PIK3C2A REN
14 hydronephrosis 30.1 ALB B2M EGF
15 danubian endemic familial nephropathy 30.1 ALB B2M
16 mercury poisoning 30.1 B2M IL18
17 obstructive nephropathy 29.9 ALB EGF HGF REN
18 hypoaldosteronism 29.9 NPPA REN
19 coronary artery anomaly 29.8 MB NPPA PIK3C2A
20 infantile liver failure syndrome 1 29.7 ALB GPT
21 acute myocardial infarction 29.7 MB NPPA PIK3C2A
22 acute liver failure 29.7 ALB GPT HGF
23 hepatic coma 29.6 ALB GPT
24 renal tuberculosis 29.6 B2M REN
25 hypertension, essential 29.6 ALB CST3 NPPA REN
26 arteries, anomalies of 29.5 ALB MB REN
27 kwashiorkor 29.5 ALB GPT
28 malignant hypertension 29.4 ADAMTS13 NPPA REN
29 obstructive jaundice 29.4 ALB GPT HGF REN
30 kidney disease 29.2 ALB B2M CST3 NPPA REN
31 heart disease 29.2 ALB CST3 NPPA PIK3C2A REN
32 liver cirrhosis 29.1 ALB GPT HGF NPPA REN
33 bilirubin metabolic disorder 29.0 ADAMTS13 ALB GPT
34 chronic kidney failure 29.0 ALB B2M CST3 NPPA REN
35 alcoholic hepatitis 29.0 ADAMTS13 ALB GPT
36 myocardial infarction 28.3 ADAMTS13 ALB CST3 MB NPPA PIK3C2A
37 hypouricemia, renal, 1 11.6
38 hypouricemia, renal, 2 11.5
39 cholera 11.4
40 glycogen storage disease v 11.1
41 hemolytic uremic syndrome, atypical 1 11.1
42 xanthinuria, type ii 11.1
43 adenine phosphoribosyltransferase deficiency 11.1
44 phosphoribosylpyrophosphate synthetase superactivity 11.0
45 korean hemorrhagic fever 11.0
46 hemolytic-uremic syndrome 11.0
47 rapidly progressive glomerulonephritis 11.0
48 leptospirosis 10.5
49 interstitial nephritis 10.5
50 glomerulonephritis 10.4

Comorbidity relations with Acute Kidney Failure via Phenotypic Disease Network (PDN): (show top 50) (show all 98)


Acquired Thrombocytopenia Active Peptic Ulcer Disease
Acute Cystitis Acute Myocardial Infarction
Acute Pancreatitis Acute Proliferative Glomerulonephritis
Acute Vascular Insufficiency of Intestine Alcoholic Liver Cirrhosis
Alzheimer Disease Aortic Aneurysm
Aortic Valve Disease 1 Bacteremia 2
Benign Renovascular Hypertension Bladder Cancer
Bladder Neck Obstruction Bleeding Disorder, Platelet-Type, 11
Bronchitis Bronchopneumonia
Candidiasis Cardiac Arrest
Cardiogenic Shock Chronic Intestinal Vascular Insufficiency
Chronic Kidney Failure Chronic Myocardial Ischemia
Chronic Rapidly Progressive Glomerulonephritis Colorectal Cancer
Cystitis Decubitus Ulcer
Deficiency Anemia Dermatomycosis
Diabetic Polyneuropathy Disseminated Intravascular Coagulation
Encephalopathy Esophageal Candidiasis
Familial Atrial Fibrillation First-Degree Atrioventricular Block
Generalized Atherosclerosis Goodpasture Syndrome
Gout Heart Disease
Hemolytic-Uremic Syndrome Hepatic Encephalopathy
Hepatitis Hepatorenal Syndrome
Hydronephrosis Hypertension, Essential
Hypertensive Encephalopathy Hyperuricemia, Pulmonary Hypertension, Renal Failure, and Alkalosis Syndrome
Hypoglycemia Hypoglycemic Coma

Graphical network of the top 20 diseases related to Acute Kidney Failure:



Diseases related to Acute Kidney Failure

Symptoms & Phenotypes for Acute Kidney Failure

MGI Mouse Phenotypes related to Acute Kidney Failure:

47
# Description MGI Source Accession Score Top Affiliating Genes
1 cardiovascular system MP:0005385 10.07 B2M CST3 HGF IL18 MB NPPA
2 homeostasis/metabolism MP:0005376 10 ADAMTS13 ALB B2M CST3 IL18 MB
3 hematopoietic system MP:0005397 9.97 ADAMTS13 B2M HGF IL18 MB NPPA
4 mortality/aging MP:0010768 9.9 ADAMTS13 ALB B2M CST3 HGF IL18
5 muscle MP:0005369 9.43 ALB CST3 IL18 MB NPPA REN
6 renal/urinary system MP:0005367 9.1 ALB NPPA PIK3C2A REN SLC22A12 TYR

Drugs & Therapeutics for Acute Kidney Failure

Drugs for Acute Kidney Failure (from DrugBank, HMDB, Dgidb, PharmGKB, IUPHAR, NovoSeek, BitterDB):

(show top 50) (show all 732)
# Name Status Phase Clinical Trials Cas Number PubChem Id
1
Dopamine Approved Phase 4,Phase 3,Phase 2,Not Applicable 62-31-7, 51-61-6 681
2
Fenoldopam Approved Phase 4,Phase 3,Phase 2 67227-56-9, 67227-57-0 3341
3
Lithium carbonate Approved Phase 4,Phase 2 554-13-2
4
Desflurane Approved Phase 4,Not Applicable 57041-67-5 42113
5
Sevoflurane Approved, Vet_approved Phase 4,Phase 3,Phase 2,Phase 1,Not Applicable,Early Phase 1 28523-86-6 5206
6
Pirfenidone Approved, Investigational Phase 4 53179-13-8 40632
7
Dexmedetomidine Approved, Vet_approved Phase 4,Phase 2,Phase 3,Not Applicable,Early Phase 1 113775-47-6 5311068 68602
8
Heparin Approved, Investigational Phase 4,Phase 3,Phase 2,Not Applicable 9005-49-6 46507594 772
9
Alprostadil Approved, Investigational Phase 4 745-65-3 5280723 149351
10
Ceftaroline fosamil Approved, Investigational Phase 4 229016-73-3
11
Miconazole Approved, Investigational, Vet_approved Phase 4,Phase 3,Phase 2,Not Applicable 22916-47-8 4189
12
Sirolimus Approved, Investigational Phase 4,Phase 3,Phase 2,Not Applicable 53123-88-9 46835353 5284616 6436030
13
Tacrolimus Approved, Investigational Phase 4,Phase 3,Phase 1,Phase 2,Not Applicable 104987-11-3 6473866 445643 439492
14
Prednisone Approved, Vet_approved Phase 4,Phase 2,Phase 3,Phase 1,Not Applicable 53-03-2 5865
15
Mycophenolic acid Approved Phase 4,Phase 3,Phase 1,Phase 2,Not Applicable 24280-93-1 446541
16
Everolimus Approved Phase 4,Phase 3,Not Applicable 159351-69-6 70789204 6442177
17
Prednisolone phosphate Approved, Vet_approved Phase 4,Phase 3,Phase 2,Not Applicable 302-25-0
18
Prednisolone Approved, Vet_approved Phase 4,Phase 3,Phase 2,Not Applicable 50-24-8 5755
19
Methylprednisolone Approved, Vet_approved Phase 4,Phase 3,Phase 2,Not Applicable 83-43-2 6741
20
Methylprednisolone hemisuccinate Approved Phase 4,Phase 3,Phase 2,Not Applicable 2921-57-5
21
Insulin glargine Approved Phase 4 160337-95-1
22
Insulin Lispro Approved Phase 4,Phase 2,Phase 3 133107-64-9
23
Metformin Approved Phase 4 657-24-9 14219 4091
24
Zinc Approved, Investigational Phase 4,Phase 3,Phase 2,Not Applicable 7440-66-6 32051
25
Tramadol Approved, Investigational Phase 4 27203-92-5 33741
26
Sufentanil Approved, Investigational Phase 4,Not Applicable,Early Phase 1 56030-54-7 41693
27
Ropivacaine Approved Phase 4,Phase 3,Not Applicable 84057-95-4 175805 71273
28
Nefopam Approved, Investigational Phase 4 13669-70-0
29
Clonidine Approved Phase 4,Phase 3 4205-90-7 2803
30
Acetaminophen Approved Phase 4,Phase 3,Phase 2,Not Applicable 103-90-2 1983
31
Ganciclovir Approved, Investigational Phase 4 82410-32-0 3454
32
Acyclovir Approved Phase 4,Phase 2 59277-89-3 2022
33
Rocuronium Approved Phase 4,Not Applicable,Early Phase 1 119302-91-9, 143558-00-3 441290
34
Etomidate Approved Phase 4,Not Applicable 33125-97-2 667484 36339
35
Midazolam Approved, Illicit Phase 4,Not Applicable 59467-70-8 4192
36
Propofol Approved, Investigational, Vet_approved Phase 4,Phase 3,Phase 1,Not Applicable 2078-54-8 4943
37
Vancomycin Approved Phase 4,Phase 3,Phase 1,Not Applicable 1404-90-6 14969 441141
38
Tobramycin Approved, Investigational Phase 4 32986-56-4 36294 5496
39
Ciprofloxacin Approved, Investigational Phase 4 85721-33-1 2764
40
Cefuroxime Approved Phase 4 55268-75-2 5479529 5361202
41
Metronidazole Approved Phase 4 443-48-1 4173
42
Acetylcysteine Approved, Investigational Phase 4,Phase 3,Phase 2,Phase 1,Not Applicable 616-91-1 12035
43
Aminophylline Approved Phase 4,Phase 3,Early Phase 1,Not Applicable 317-34-0 9433
44
carbamide peroxide Approved Phase 4,Not Applicable 124-43-6
45
tannic acid Approved Phase 4,Phase 3,Phase 2,Not Applicable,Early Phase 1 1401-55-4
46
Benzocaine Approved, Investigational Phase 4,Phase 3,Phase 2,Not Applicable,Early Phase 1 1994-09-7, 94-09-7 2337
47
Sodium Citrate Approved, Investigational Phase 4,Phase 3,Phase 2,Phase 1,Not Applicable 68-04-2
48
Dalteparin Approved Phase 4,Phase 3 9005-49-6
49
Thrombin Approved, Investigational Phase 4,Phase 3,Phase 2,Not Applicable
50
Colistin Approved Phase 4,Phase 3,Not Applicable 1066-17-7, 1264-72-8 5311054

Interventional clinical trials:

(show top 50) (show all 1594)
# Name Status NCT ID Phase Drugs
1 Fenoldopam for Prevention of Acute Kidney Injury Unknown status NCT01690832 Phase 4 standard saline infusion;fenoldopam infusion
2 Lithium in Acute Kidney Injury Unknown status NCT03056248 Phase 4 Placebo oral capsule;Lithium Carbonate
3 Anesthetic Agents and Acute Kidney Injury After Liver Resection Surgery Unknown status NCT02174575 Phase 4 Sevoflurane;Desflurane
4 Pirfenidone Effect on the Recovery of Renal Function in Septic Acute Kidney Injury Unknown status NCT02530359 Phase 4 Pirfenidone extended release;Placebo equivalent
5 Nutritional Therapy to Prevent Progression of Acute Kidney Injury to Chronic Kidney Disease Unknown status NCT02831062 Phase 4
6 Short-Term Alpha Lipoic Acid Therapy for Prevention of Contrast-induced Acute Kidney Injury and Endothelial Dysfunction in Type 2 Diabetes Unknown status NCT01978405 Phase 4 Alpha lipoic acid
7 Early Continuous Renal Replacement Therapies (CRRT) in Patients With Severe Sepsis or Septic Shock With Acute Kidney Injury Unknown status NCT00837057 Phase 4
8 The Effects of Dexmedetomidine on Postoperative Renal Function in Valvular Heart Surgery Unknown status NCT01886079 Phase 4 dexmedetomidine;Saline
9 Minimizing Contrast Utilization With IVUS Guidance in Coronary Angioplasty to Avoid Acute Nephropathy Unknown status NCT02743156 Phase 4
10 Limiting IV Chloride to Reduce AKI After Cardiac Surgery Unknown status NCT02020538 Phase 4
11 Preventing contrAst Induced Nephropathy After TranscathEter Aortic Valve Replacement Unknown status NCT03121053 Phase 4 sodium bicarbonate;hypotone saline
12 Comparison of Slow Efficiency Daily Dialysis (SLEDD) With Unfractionated Heparin Versus Citrasate in Critically Ill Patients. Unknown status NCT01228292 Phase 4 Unfractionated heparin;Citrasate
13 Efficacy and Safety of Alprostadil Prevent Contrast Induced Nephropathy Unknown status NCT01722513 Phase 4 Alprostadil ﹠control
14 Protective Effects of Oral L-Arginine CI-AKI Unknown status NCT02455960 Phase 4
15 Efficacy and Safety of Heparin-coated Surface-treated Polyacrylonitrile Membrane Hemofilter in Critical Ill CRRT Patients Unknown status NCT02355873 Phase 4
16 Antibiotic Prophylaxis in Open Fractures Unknown status NCT02937181 Phase 4 Ceftaroline
17 Cytokines Evaluation in Early Calcineurin Inhibitors Withdrawn on Renal Transplant Unknown status NCT01239472 Phase 4 everolimus
18 Steroids In caRdiac Surgery Trial (SIRS Trial) Unknown status NCT00427388 Phase 4 Methylprednisolone
19 Abrogation of Mitral Regurgitation Using the MitraClip System in High-Risk Patients Unsuitable for Surgery Unknown status NCT01431222 Phase 4
20 Metformin and Sitagliptin Therapy for Adult Patients With Type 2 Diabetes Admitted to the General Medical Unit Unknown status NCT02250794 Phase 4 metformin and sitagliptin;insulin glargine and insulin lispro;metformin and sitagliptin;insulin glargine and insulin lispro
21 Epidural Analgesia for Pancreatitis (Epipan Study) Unknown status NCT02126332 Phase 4
22 The Pacing vs No Pacing Study - PNP Study Unknown status NCT02498639 Phase 4
23 PTH - Preemptive Treatment for Herpesviridae Unknown status NCT02152358 Phase 4 Aciclovir;Ganciclovir;Placebo
24 The Effect of Branched-chain Amino Acid on the Improvement of Serum Albumin Level in Cirrhotic Patients With Ascites Unknown status NCT02755701 Phase 4 Branched-chain Amino Acid;Placebo
25 Target Controlled Infusion of Etomidate or Propofol for Anesthesia of Thoracoscopic Mitral Valve Replacement Surgery Unknown status NCT02644980 Phase 4 Propofol;Etomidate;Induction of anesthesia;Maintenance of anesthesia
26 Aerosolized Antibiotics in the Treatment of Ventilator Associated Pneumonia Unknown status NCT02478710 Phase 4 Aerosolized Tobramycin or Vancomycin;Aerosolized Placebo
27 Parenteral Antibiotics Compared to Combination of Oral and Parenteral Antibiotics in Colorectal Surgery Prophylaxis Unknown status NCT02505581 Phase 4 Extra dosage - cefuroxime (750mg) I.V;Cefuroxime 750mg oral;Metronidazole 250mg oral;Metronidazole 1,5gr Intravenous;Cefuroxime 1g Intravenous
28 Effect of the Intensity of Continuous Renal Replacement Therapy in Patients With Acute Kidney Injury Completed NCT01560650 Phase 4
29 Effect of N-acetylcysteine on Prevention of Acute Kidney Injury in High Risk Patients Undergoing Off-pump Coronary Artery Bypass Graft Completed NCT01394419 Phase 4 N-acetylcysteine;Saline
30 Augmented Vs. Normal Renal Replacement Therapy in Severe Acute Renal Failure (ARF). Completed NCT00221013 Phase 4
31 Metabolic Pattern of Cyclosporine A and Acute Renal Failure Completed NCT00264355 Phase 4 cyclosporine A
32 The Effect of Atorvastatin on Prevention of Postoperative Acute Kidney Injury in Patients Undergoing Aortic Surgery Completed NCT02157337 Phase 4 Atorvastatin;placebo
33 Personalized Versus Standard Hydration for Prevention of CI-AKI: a Randomized Trial With Bioimpedance Analysis Completed NCT02225431 Phase 4 sodium chloride infusion
34 Atorvastatin Versus Rosuvastatin on Contrast Induced Acute Kidney Injury (PRATO-ACS 2) Completed NCT01870804 Phase 4 Rosuvastatin;Atorvastatin
35 The Optimal Mode of Renal Replacement Therapy in Acute Kidney Injury (OMAKI) Study Completed NCT00675818 Phase 4
36 Aminophylline and Contrast Induced Nephropathy in Acute Myocardial Infarction Completed NCT01594489 Phase 4 Aminophylline;Hydration plus N-acetylcisteine
37 Hannover Dialysis Outcome Study Completed NCT00529139 Phase 4
38 The Effect of the Forced Diuresis With Matched Hydration in Reducing Acute Kidney Injury During TAVI Completed NCT01866800 Phase 4 Conventional Treatment
39 Prostacyclin's Effect on Platelet Responsiveness Completed NCT00890214 Phase 4 prostacyclin;heparin
40 Prevention of Acute Kidney Injury by Erythropoietin in Thoracic Aorta Surgery With Hypothermic Cardiac Arrest Completed NCT01369732 Phase 4 recombinant human erythropoietin;saline
41 Rosuvastatin Prevent Contrast Induced Acute Kidney Injury in Patients With Diabetes Completed NCT00786136 Phase 4 rosuvastatin
42 Early Hydration in Acute Myocardial Infarction Completed NCT01742130 Phase 4 sodium bicarbonate solution;Isotonic saline
43 Efficacy of RIPC to Reduce AKI for Patients Undergoing PCI Completed NCT02195726 Phase 4
44 Citrate-based Regional Anticoagulation Versus Heparin for Continuous Renal Replacement Therapy Completed NCT01269112 Phase 4
45 Perioperative Evaluation of Terlipressin Infusion During Living Donor Liver Transplantation on Incidence of Acute Kidney Completed NCT02059460 Phase 4 Terlipressin;placebo
46 The Effect of Sodium Bicarbonate on Postoperative Renal Function in Infective Endocarditis Patients Undergoing Open Heart Surgery Completed NCT01920126 Phase 4 sodium bicarbonate;Saline
47 Effect of Intraoperative Dexmedetomidine on Development of Acute Kidney Injury Completed NCT02641938 Phase 4 Dexmedetomidine;Normal Saline
48 Trial to Assess the Efficacy and Safety of Nafamostat Mesilate During Continuous Renal Replacement Therapy Completed NCT02478242 Phase 4 Nafamostat mesilate;Normal saline
49 A Comparison of Propofol Based Total Intravenous Anesthesia and Sevoflurane Based Balanced Anesthesia on Renal Protection During Lung Transplantation Under Extracorporeal Membrane Oxygenation - A Prospective, Randomized Trial Completed NCT02009280 Phase 4 Administration of anesthesia: Propofol;Administration of anesthesia: Sevoflurane
50 Pharmacokinetics of Ertapenem in Continuous Venovenous Hemodialysis Completed NCT00877370 Phase 4 ertapenem

Search NIH Clinical Center for Acute Kidney Failure

Inferred drug relations via UMLS 74 / NDF-RT 52 :


Cell-based therapeutics:


LifeMap Discovery
Data from LifeMap, the Embryonic Development and Stem Cells Database
Read about Acute Kidney Failure cell therapies at LifeMap Discovery.

Cochrane evidence based reviews: acute kidney injury

Genetic Tests for Acute Kidney Failure

Anatomical Context for Acute Kidney Failure

MalaCards organs/tissues related to Acute Kidney Failure:

42
Kidney, Heart, Liver, Neutrophil, Testes, Lung, Endothelial
LifeMap Discovery
Data from LifeMap, the Embryonic Development and Stem Cells Database

Cells/anatomical compartments in embryo or adult related to Acute Kidney Failure:
# Tissue Anatomical CompartmentCell Relevance
1 Bone Bone Marrow Bone Marrow Stromal Cells Potential therapeutic candidate
2 Adipose Subcutaneous White Adipose Mesenchymal Stem Cells Potential therapeutic candidate
3 Kidney Proximal Tubule Proximal Tubule Cells Affected by disease, potential therapeutic candidate

Publications for Acute Kidney Failure

Articles related to Acute Kidney Failure:

(show top 50) (show all 63)
# Title Authors Year
1
Impact of postoperative acute kidney failure in long-term survival after heart valve surgery. ( 30844065 )
2019
2
Postoperative acute kidney failure and incision skin necrosis caused by a giant retroperitoneal paraganglioma. ( 30855356 )
2019
3
Etoricoxib-induced immune hemolytic anemia: first case presenting acute kidney failure. ( 30865300 )
2019
4
Acute kidney failure and discrepant values of urinary proteins: When the case is not "crystal clear". ( 30890413 )
2019
5
Acute Kidney Failure in a Young African American Male. ( 30911422 )
2019
6
Acute Kidney Failure as a Single Complication of Varicella Virus Infection in an Adult Patient. ( 30197901 )
2018
7
Skin and mucosal ulcerations and acute kidney failure due to methotrexate toxicity in a patient with non-Hodgkin's lymphoma. ( 30829285 )
2018
8
Clinical case report: a rare cause of acute kidney failure - tissue is the issue. ( 27253186 )
2017
9
Acute kidney failure due to polyarteritis nodosa. ( 27939915 )
2017
10
Pemetrexed-induced acute kidney failure following irreversible renal damage: two case reports and literature review. ( 28491851 )
2017
11
Necroptosis and ferroptosis are alternative cell death pathways that operate in acute kidney failure. ( 28551825 )
2017
12
Novel presentation of rituximab-induced herpes zoster: urinary retention and acute kidney failure. ( 25079963 )
2016
13
Proliferative C4 Dense Deposit Disease, Acute Thrombotic Microangiopathy, a Monoclonal Gammopathy, and Acute Kidney Failure. ( 26704376 )
2016
14
Inhibition of Notch Signaling Ameliorates Acute Kidney Failure and Downregulates Platelet-Derived Growth Factor Receptor β in the Mouse Model. ( 26939110 )
2016
15
Hyperkalemia and acute kidney failure associated with preoperative uterine artery embolization for a large uterine fibroid: a case report. ( 27799061 )
2016
16
Possible Simeprevir/Sofosbuvir-Induced Hepatic Decompensation With Acute Kidney Failure. ( 30766171 )
2016
17
Clinical Scenarios in Acute Kidney Injury: Pre-Renal Acute Kidney Injury. ( 27169621 )
2016
18
Elevated biomarkers and contrast-induced acute kidney failure: what comes first the chicken or the egg? ( 25684714 )
2015
19
Acute kidney failure associated with anaphylactic shock caused by diclofenac sodium. ( 25899205 )
2015
20
Older adults with CKD and acute kidney failure: do we know enough for critical shared decision making? ( 24262792 )
2014
21
Tuberous sclerosis presenting with acute kidney failure, pyelonephritis, and polycystic kidney disease. ( 25001142 )
2014
22
Successful reversal of acute kidney failure by ultrasound-accelerated thrombolysis of an occluded renal artery. ( 25276140 )
2014
23
Crohnic kidney disease: recurrent acute kidney failure in a patient with Crohn's disease. ( 25599054 )
2014
24
Monitoring of metformin-induced lactic acidosis in a diabetic patient with acute kidney failure and effect of hemodialysis. ( 23149294 )
2013
25
Cardiac catheterization and postoperative acute kidney failure in congenital heart pediatric patients. ( 23780421 )
2013
26
Acute kidney failure with renal carcinomatous lymphangitis secondary to advanced colon cancer. ( 23903432 )
2013
27
The case: fever, myalgia, visual disorders, and acute kidney failure in a pregnant woman. Diagnosis: Severe acute hantavirus infection. ( 23989371 )
2013
28
Joint pain, digital necrosis and acute kidney failure in small-vessel autoimmune disease. ( 26019859 )
2013
29
Malignant hypertension with protracted but not definitive oligoanuric acute kidney failure. ( 27293574 )
2013
30
Urinalysis and pre-renal acute kidney injury: time to move on. ( 23659200 )
2013
31
Early biomarkers of acute kidney failure after heart angiography or heart surgery in patients with acute coronary syndrome or acute heart failure. ( 22130209 )
2012
32
New insights in acute kidney failure in the critically ill. ( 22923149 )
2012
33
Acute kidney failure complicating carbon monoxide poisoning. ( 22992968 )
2012
34
Female with rash, acute kidney failure and rheumatoid arthritis. ( 23023360 )
2012
35
Renal Replacement Therapy in Acute Kidney Failure due to Rhabdomyolysis. ( 24826338 )
2012
36
Primary renal lymphoma: an uncommon diagnosis for acute kidney failure. ( 26019832 )
2012
37
Renal tubular Fas ligand mediates fratricide in cisplatin-induced acute kidney failure. ( 20811331 )
2011
38
Acute kidney failure in the context of a Tako-Tsubo syndrome. ( 21738255 )
2011
39
Hemolysis and acute kidney failure. ( 20605299 )
2010
40
Effective use of continuous arteriovenous hemodialysis in a critically ill human immunodeficiency virus-positive patient with acute kidney failure. ( 20622320 )
2010
41
Acute tubular necrosis and pre-renal acute kidney injury: utility of urine microscopy in their evaluation- a systematic review. ( 19921458 )
2010
42
Acute kidney failure in the third trimester of pregnancy. ( 19008026 )
2009
43
Acute bacterial pyelonephritis resulting in acute kidney failure: a complication of chronic non-steroidal anti-inflammatory drug use? ( 19335847 )
2009
44
Acute kidney failure in neonatal period. ( 19617661 )
2009
45
Acute kidney failure and an epigastric mass. ( 25949294 )
2009
46
Recurrent acute kidney failure due to McArdle disease. ( 19377243 )
2008
47
RIFLE classification of acute kidney failure in intensive care. ( 17639826 )
2007
48
Focus on hepatitis. Low CD4 count + HCV coinfection = acute kidney failure. ( 17366669 )
2006
49
Summaries for patients. Plasma exchange treatment is not effective in treating acute kidney failure caused by multiple myeloma. ( 16330784 )
2005
50
Postpartum acute kidney failure and hyponatremia: a clinical enigma. ( 15473598 )
2004

Variations for Acute Kidney Failure

Expression for Acute Kidney Failure

Search GEO for disease gene expression data for Acute Kidney Failure.

Pathways for Acute Kidney Failure

Pathways related to Acute Kidney Failure according to GeneCards Suite gene sharing:

# Super pathways Score Top Affiliating Genes
1 10.92 ALB EGF HGF

GO Terms for Acute Kidney Failure

Cellular components related to Acute Kidney Failure according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 extracellular exosome GO:0070062 9.86 ALB B2M CST3 EGF GPT MB
2 endoplasmic reticulum lumen GO:0005788 9.62 ADAMTS13 ALB B2M CST3
3 extracellular region GO:0005576 9.61 ADAMTS13 ALB B2M CST3 EGF HGF
4 platelet alpha granule lumen GO:0031093 9.33 ALB EGF HGF
5 extracellular space GO:0005615 9.32 ADAMTS13 ALB B2M CST3 EGF GPT

Biological processes related to Acute Kidney Failure according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 positive regulation of protein kinase B signaling GO:0051897 9.43 EGF HGF IL18
2 platelet degranulation GO:0002576 9.33 ALB EGF HGF
3 cellular protein metabolic process GO:0044267 8.92 ALB B2M CST3 NPPA
4 phosphatidylinositol phosphorylation GO:0046854 8.65 PIK3C2A

Sources for Acute Kidney Failure

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
17 EFO
18 ExPASy
20 FMA
29 GO
30 GTR
31 HGMD
32 HMDB
33 HPO
34 ICD10
35 ICD10 via Orphanet
36 ICD9CM
37 IUPHAR
38 KEGG
39 LifeMap
41 LOVD
43 MedGen
45 MeSH
46 MESH via Orphanet
47 MGI
50 NCI
51 NCIt
52 NDF-RT
55 NINDS
56 Novoseek
58 OMIM
59 OMIM via Orphanet
63 PubMed
65 QIAGEN
70 SNOMED-CT via HPO
71 SNOMED-CT via Orphanet
72 TGDB
73 Tocris
74 UMLS
75 UMLS via Orphanet
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