MCID: ACT072
MIFTS: 34

Acute Laryngitis

Categories: Infectious diseases, Oral diseases, Respiratory diseases

Aliases & Classifications for Acute Laryngitis

MalaCards integrated aliases for Acute Laryngitis:

Name: Acute Laryngitis 12 15 74

Classifications:



External Ids:

Disease Ontology 12 DOID:9396
ICD9CM 36 464.0 464.01
NCIt 51 C26688
SNOMED-CT 69 6655004
ICD10 34 J04.0

Summaries for Acute Laryngitis

Disease Ontology : 12 A laryngitis which lasts less than a few days.

MalaCards based summary : Acute Laryngitis is related to laryngitis and chronic laryngitis. An important gene associated with Acute Laryngitis is EDN3 (Endothelin 3). The drugs Fluticasone and Omeprazole have been mentioned in the context of this disorder. Affiliated tissues include bone, colon and neutrophil.

Related Diseases for Acute Laryngitis

Diseases in the Laryngitis family:

Chronic Laryngitis Viral Laryngitis
Acute Laryngitis

Diseases related to Acute Laryngitis via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50) (show all 93)
# Related Disease Score Top Affiliating Genes
1 laryngitis 32.4 ATP12A ATP4A
2 chronic laryngitis 29.5 ATP12A ATP4A
3 viral laryngitis 11.1
4 laryngotracheitis 10.5
5 tracheitis 10.3
6 spasmodic dystonia 10.2
7 dystonia 10.2
8 spasmodic dysphonia 10.2
9 diclofenac allergy 10.1 ATP12A ATP4A
10 gastroduodenal crohn's disease 10.1 ATP12A ATP4A
11 neonatal candidiasis 10.1 ATP12A ATP4A
12 photoallergic dermatitis 10.1 ATP12A ATP4A
13 squamous papillomatosis 10.1 ATP12A ATP4A
14 toxic megacolon 10.1 ATP12A ATP4A
15 aspiration pneumonitis 10.1 ATP12A ATP4A
16 gastrointestinal neuroendocrine benign tumor 10.1 ATP12A ATP4A
17 gastric antral vascular ectasia 10.1 ATP12A ATP4A
18 granulomatous gastritis 10.1 ATP12A ATP4A
19 esophageal candidiasis 10.1 ATP12A ATP4A
20 gastric neuroendocrine neoplasm 10.1 ATP12A ATP4A
21 duodenitis 10.1 ATP12A ATP4A
22 rumination disorder 10.1 ATP12A ATP4A
23 active peptic ulcer disease 10.1 ATP12A ATP4A
24 congenital disorder of deglycosylation 10.1 ATP12A ATP4A
25 bladder calculus 10.1 ATP12A ATP4A
26 bile reflux 10.1 ATP12A ATP4A
27 capillary disease 10.1 ATP12A ATP4A
28 peptic esophagitis 10.1 ATP12A ATP4A
29 dyskinesia of esophagus 10.1 ATP12A ATP4A
30 hernia, hiatus 10.1 ATP12A ATP4A
31 anismus 10.0 ATP12A ATP4A
32 postsurgical hypothyroidism 10.0 ATP12A ATP4A
33 lymphocytic colitis 10.0 ATP12A ATP4A
34 esophageal atresia/tracheoesophageal fistula 10.0 ATP12A ATP4A
35 clostridium difficile colitis 10.0 ATP12A ATP4A
36 diarrhea 1, secretory chloride, congenital 10.0 ATP12A ATP4A
37 esophagitis, eosinophilic, 1 10.0 ATP12A ATP4A
38 microscopic colitis 10.0 ATP12A ATP4A
39 laryngeal tuberculosis 10.0 ATP12A ATP4A
40 eosinophilic gastritis 10.0 ATP12A ATP4A
41 esophagus adenocarcinoma 10.0 ATP12A ATP4A
42 chronic intestinal vascular insufficiency 10.0 ATP12A ATP4A
43 polyposis, skin pigmentation, alopecia, and fingernail changes 10.0 ATP12A ATP4A
44 jejunoileitis 10.0 ATP12A ATP4A
45 pancreatic steatorrhea 10.0 ATP12A ATP4A
46 esophageal varix 10.0 ATP12A ATP4A
47 superior mesenteric artery syndrome 10.0 ATP12A ATP4A
48 gastric lymphoma 10.0 ATP12A ATP4A
49 lower urinary tract calculus 10.0 ATP12A ATP4A
50 myopathy, x-linked, with excessive autophagy 10.0 ATP12A ATP4A

Graphical network of the top 20 diseases related to Acute Laryngitis:



Diseases related to Acute Laryngitis

Symptoms & Phenotypes for Acute Laryngitis

Drugs & Therapeutics for Acute Laryngitis

Drugs for Acute Laryngitis (from DrugBank, HMDB, Dgidb, PharmGKB, IUPHAR, NovoSeek, BitterDB):

(show top 50) (show all 107)
# Name Status Phase Clinical Trials Cas Number PubChem Id
1
Fluticasone Approved, Experimental Phase 4,Phase 3 90566-53-3 62924
2
Omeprazole Approved, Investigational, Vet_approved Phase 4,Not Applicable 73590-58-6 4594
3
Dexamethasone Approved, Investigational, Vet_approved Phase 4,Not Applicable 50-02-2 5743
4
Dexamethasone acetate Approved, Investigational, Vet_approved Phase 4,Not Applicable 1177-87-3
5
Epinephrine Approved, Vet_approved Phase 4,Not Applicable 51-43-4 5816
6
Racepinephrine Approved Phase 4,Not Applicable 329-65-7 838
7
Esomeprazole Approved, Investigational Phase 4 161796-78-7, 161973-10-0, 119141-88-7 9568614 4594
8
Meloxicam Approved, Vet_approved Phase 4 71125-38-7 54677470 5281106
9
Diclofenac Approved, Vet_approved Phase 4 15307-86-5 3033
10
Prednisone Approved, Vet_approved Phase 4 53-03-2 5865
11
Lansoprazole Approved, Investigational Phase 4 103577-45-3 3883
12
Dexlansoprazole Approved, Investigational Phase 4 138530-94-6, 103577-45-3 9578005
13 Adrenergic Agonists Phase 4
14
Salmeterol xinafoate Phase 4 94749-08-3 56801
15 Adrenergic beta-2 Receptor Agonists Phase 4
16 Fluticasone-Salmeterol Drug Combination Phase 4
17 Sympathomimetics Phase 4
18 glucocorticoids Phase 4,Phase 3,Not Applicable
19 Bronchodilator Agents Phase 4,Phase 3,Not Applicable
20 Adrenergic beta-Agonists Phase 4
21 Adrenergic Agents Phase 4,Phase 2,Phase 3
22 Hormones, Hormone Substitutes, and Hormone Antagonists Phase 4,Phase 3,Not Applicable
23 Dermatologic Agents Phase 4,Phase 3
24 Neurotransmitter Agents Phase 4,Phase 2,Phase 3
25 Hormones Phase 4,Phase 2,Phase 3,Not Applicable
26 Anti-Inflammatory Agents Phase 4,Phase 3,Not Applicable
27 Peripheral Nervous System Agents Phase 4,Phase 2,Phase 3,Not Applicable
28 Respiratory System Agents Phase 4,Phase 3,Not Applicable
29 Anti-Asthmatic Agents Phase 4,Phase 3,Not Applicable
30 Anti-Allergic Agents Phase 4,Phase 3
31 Hormone Antagonists Phase 4,Phase 3,Not Applicable
32 Autonomic Agents Phase 4,Phase 3,Not Applicable
33 Proton Pump Inhibitors Phase 4,Phase 2,Phase 3,Not Applicable
34 Gastrointestinal Agents Phase 4,Phase 2,Phase 3,Not Applicable
35 HIV Protease Inhibitors Phase 4,Not Applicable
36 Antineoplastic Agents, Hormonal Phase 4,Phase 3,Not Applicable
37
protease inhibitors Phase 4,Not Applicable
38 Antiemetics Phase 4,Phase 3,Not Applicable
39 BB 1101 Phase 4,Not Applicable
40 Epinephryl borate Phase 4,Not Applicable
41 Anti-Ulcer Agents Phase 4,Phase 2,Phase 3,Not Applicable
42 Antacids Phase 4,Phase 2,Phase 3,Not Applicable
43 Analgesics Phase 4,Phase 2,Phase 3
44 Anti-Inflammatory Agents, Non-Steroidal Phase 4
45 Cyclooxygenase 2 Inhibitors Phase 4
46 Cyclooxygenase Inhibitors Phase 4
47 Analgesics, Non-Narcotic Phase 4,Phase 2,Phase 3
48 Antirheumatic Agents Phase 4
49 Adrenergic alpha-Agonists Phase 4
50 Vasoconstrictor Agents Phase 4

Interventional clinical trials:

(show all 39)
# Name Status NCT ID Phase Drugs
1 Study to Assess the Incidence of Local Oropharyngeal and Laryngeal Adverse Effects of Advair DISKUS 250/50 Mcg BID Unknown status NCT00235053 Phase 4 fluticasone/salmeterol DISKUS 250/50
2 Chronic Posterior Laryngitis With Suspected Laryngopharyngeal Reflux Completed NCT00628667 Phase 4 Esomeprazole;Placebo
3 Efficacy and Safety of Meloxicam Suspension Versus Diclofenac Suspension or Nimesulide Suspension in Patients With a Diagnosis of Acute, Non-bacterial Pharyngitis, Pharyngotonsillitis or Laryngitis Completed NCT02229747 Phase 4 Meloxicam;Diclofenac;Nimesulide
4 Quality of Life Validation in Laryngitis Completed NCT00641264 Phase 4 Omeprazole
5 Community Care for Croup (RCT) Completed NCT01042145 Phase 4 Prednisone;Dexamethasone
6 The Effect and Safety of Low Dose Nebulized Epinephrine in Croup Recruiting NCT01664507 Phase 4 conventional dose epinephrine;low dose epinephrine
7 Comparison of Dexamethasone Oral Preparations to Assess Taste and Acceptance in Children With Asthma and Croup Recruiting NCT03705273 Phase 4 Dexamethasone IV for PO;Dexamethasone crushed tablets
8 Safety and Efficacy of Lansoprazole 30mg Twice Daily in Treatment of Laryngitis Associated With Gastroesophageal Reflux Terminated NCT00369265 Phase 4 Lansoprazole
9 Laparoscopic Lightweight Mesh Repair of Large Hiatal Hernias Unknown status NCT01408108 Phase 3
10 Laparoscopic Repair of Giant Hiatal Hernias With Nitinol-framed Lightweight Polytetrafluoroethylene Mesh Unknown status NCT01780285 Phase 3
11 Lactobacillus Reuteri DSM 17938 and Prevention of Respiratory and Gastrointestinal Infections in Mexican Infants Unknown status NCT01249911 Phase 3
12 Laryngopharyngeal Reflux and Proton Pump Inhibitor (PPI) Treatment Completed NCT00204698 Phase 2, Phase 3 Aciphex
13 CLEARI (Clinical Efficacy Assessment on Recurrent Upper-Respiratory Tract Infections) Study Completed NCT01948856 Phase 3 J022X ST;Placebo
14 Vitamin D Supplementation and Male Infertility: The CBG-study a Randomized Clinical Trial Completed NCT01304927 Phase 2, Phase 3 Cholecalciferol and calcium
15 E. Coli Nissle 1917 - Suspension for Infection Prophylaxis Active, not recruiting NCT02802059 Phase 3 EcN-Suspension;Placebo
16 Treatment of Chronic Laryngitis With Amitriptyline Suspended NCT02552225 Phase 2, Phase 3 Amitriptyline
17 Trial of the Treatment of Chronic Laryngitis With Amitryptiline Terminated NCT02434523 Phase 2, Phase 3 Amitriptyline
18 Management of Recurrent Croup Terminated NCT01748162 Phase 3 Fluticasone;Prednisolone IF needed
19 Efficacy of Nebulized Beclomethasone Dipropionate (BDP) in the Treatment of Moderate Croup Terminated NCT00938353 Phase 3 beclomethasone dipropionate suspension for nebulisation 800 mcg/2 ml;Placebo solution for nebulisation 2 ml
20 Treatment of Acute Tracheitis and Laryngitis With Essential Oils of Aromatic Plants Completed NCT00611390 Phase 1, Phase 2
21 A Study to Evaluate the Safety, Tolerability, Immunogenicity and Vaccine-like Viral Shedding of MEDI-534, Against Respiratory Syncytial Virus (RSV) and Parainfluenza Virus Type 3 (PIV3), in Healthy 6 to <24 Month-old Children and in 2 Month-old Infants Completed NCT00686075 Phase 1, Phase 2
22 Comparing Different Ways of Delivering Humidity to Children With Croup Completed NCT00230841 Phase 2
23 A Randomized, Double-Blind, Placebo-Controlled Study to Evaluate Safety of MEDI-559 in Healthy 1 to <24 Month-Old Children Completed NCT00767416 Phase 1, Phase 2
24 Safety and Tolerability Study to Evaluate MEDI-534 in Children 6 to < 24 Months of Age Completed NCT00493285 Phase 1
25 Positive Predictive Value of the Dx-pH Probe for Predicting PPI Response in LPR Unknown status NCT01755221 Not Applicable
26 Intestinal Microbiota Composition After Antibiotic Treatment in Early Life Unknown status NCT02536560
27 Comparison Between Budesonide and Dexamethasone Treatments for Respiratory Discomfort After Extubation on Children Unknown status NCT02056379 Not Applicable Budesonide;Dexamethasone
28 Laryngeal and Esophageal EGF-r Expression in Patients With Reflux Laryngitis Completed NCT01806220 Not Applicable
29 Non Interventional Study (NIS) Regarding the Application of Ectoin Mund- & Rachenspray in Patients With Acute Laryngitis and/or Acute Pharyngitis Completed NCT02160912
30 Salivary Epidermal Growth Factor (EGF) Concentration Before and After Treatment of Reflux Laryngitis Completed NCT01389401 omeprazole
31 Prospective Double-blinded Randomized Controlled Trial of 12-weeks High Dose Rabeprazole (Pariet) in the Treatment of Reflux Laryngitis in Chinese Patients Completed NCT00517114 Not Applicable Rabeprazole 20mg twice daily
32 Inter-rater Reliability of the Reflux Finding Score Among Gastroenterologists Completed NCT02048449
33 Nudging Guideline-concordant Antibiotic Prescribing Using Public Commitments Completed NCT01767064 Not Applicable
34 Special Drug Use Investigation for CLAVAMOX® (Amoxicillin/Clavulanate) Pediatrics Dry Syrup (Every Indication Excluded Otitis Media) Completed NCT01406275 Amoxicillin and clavulanate
35 The Effect of Zinc Acetate Lozenges on the Rate of Recovery From the Common Cold Completed NCT03309995 Not Applicable
36 A Post Marketing Evaluation of the Effectiveness of FluMist Risk Minimization Plan in Children Completed NCT00626808 No Intervention
37 Polish Mother and Child Cohort Study (REPRO_PL) - Follow up of the Children. Completed NCT01861548
38 Repeated Versus Varied Simulation Scenarios to Teach Medical Students the Management of a Pediatric Asthma Exacerbation Completed NCT02754310 Not Applicable
39 A Cluster Controlled Trial Comparing Three Methods of Disseminating Practice Guidelines for Children With Croup Terminated NCT00147849 Not Applicable

Search NIH Clinical Center for Acute Laryngitis

Genetic Tests for Acute Laryngitis

Anatomical Context for Acute Laryngitis

MalaCards organs/tissues related to Acute Laryngitis:

42
Bone, Colon, Neutrophil, Skin

Publications for Acute Laryngitis

Articles related to Acute Laryngitis:

(show all 32)
# Title Authors Year
1
Antibiotics for acute laryngitis in adults. ( 26002823 )
2015
2
Acute laryngitis superimposed on chronic laryngitis. ( 23460211 )
2013
3
Antibiotics for acute laryngitis in adults. ( 23543536 )
2013
4
Antibiotics for acute laryngitis in adults. ( 17443555 )
2007
5
Superior laryngeal neuralgia after acute laryngitis and treatment with a single injection of a local anesthetic. ( 17875862 )
2007
6
Antibiotics for acute laryngitis in adults. ( 15674965 )
2005
7
Antibiotics for acute laryngitis in adults. ( 16035684 )
2005
8
Effect of meteorological parameters on acute laryngitis in adults. ( 12403130 )
2002
9
Acute laryngitis in a professional singer. ( 11480296 )
2001
10
Acute laryngitis. ( 11933444 )
2000
11
Acute laryngitis. ( 10935296 )
2000
12
Acute laryngitis in the rat induced by Moraxella catarrhalis and Bordetella pertussis: number of neutrophils, dendritic cells, and T and B lymphocytes accumulating during infection in the laryngeal mucosa strongly differs in adjacent locations. ( 10590036 )
1999
13
Some aerodynamic and acoustic characteristics of acute laryngitis. ( 9297681 )
1997
14
Moraxella catarrhalis in acute laryngitis: infection or colonization? ( 8769627 )
1996
15
Erythromycin in acute laryngitis in adults. ( 8457123 )
1993
16
Acute laryngitis in adults: results of erythromycin treatment. ( 1632252 )
1992
17
Elevated creatine phosphokinase and creatine phosphokinase-MB in acute laryngitis. ( 2046207 )
1991
18
Acute laryngitis in adults: diagnosis, etiology, treatment. ( 3144113 )
1988
19
Inefficacy of penicillin V in acute laryngitis in adults. Evaluation from results of double-blind study. ( 3918495 )
1985
20
Acute laryngitis associated with rotavirus gastroenteritis. ( 6631034 )
1983
21
High isolation rate of Branhamella catarrhalis from the nasopharynx in adults with acute laryngitis. ( 7006061 )
1980
22
Radiological features of acute laryngitis in infancy. ( 4636301 )
1972
23
The treatment with antiserum of acute laryngitis caused by Hemophilus influenzae. ( 21007906 )
1945
24
Acute Laryngitis-I. ( 29814375 )
1910
25
Acute Laryngitis-II. ( 29814516 )
1910
26
Pulsus Paradoxus in Acute Laryngitis. ( 20755517 )
1895
27
PULSUS PARADOXUS in ACUTE LARYNGITIS. ( 20754305 )
1893
28
Report of a Case of Acute Laryngitis, in Which Laryngo-Tracheotomy Was Performed. ( 30748272 )
1864
29
Clinical Lecture on Acute Laryngitis. ( 20744011 )
1862
30
Case of Acute Laryngitis, with Observations. ( 20794577 )
1849
31
Case of Acute Laryngitis: with Remarks on Dr. Wardell's Cases of Spasma Glottidis. ( 20794401 )
1848
32
Case of acute laryngitis in which tracheotomy was performed. ( 21379785 )
1841

Variations for Acute Laryngitis

Expression for Acute Laryngitis

Search GEO for disease gene expression data for Acute Laryngitis.

Pathways for Acute Laryngitis

GO Terms for Acute Laryngitis

Cellular components related to Acute Laryngitis according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 extracellular space GO:0005615 8.92 ATP4A CRP EDN3 F3

Biological processes related to Acute Laryngitis according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 potassium ion transport GO:0006813 9.4 ATP12A ATP4A
2 potassium ion import across plasma membrane GO:1990573 9.37 ATP12A ATP4A
3 ATP hydrolysis coupled proton transport GO:0015991 9.32 ATP12A ATP4A
4 cellular sodium ion homeostasis GO:0006883 9.26 ATP12A ATP4A
5 establishment or maintenance of transmembrane electrochemical gradient GO:0010248 9.16 ATP12A ATP4A
6 cellular potassium ion homeostasis GO:0030007 8.96 ATP12A ATP4A
7 sodium ion export across plasma membrane GO:0036376 8.62 ATP12A ATP4A

Molecular functions related to Acute Laryngitis according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 sodium:potassium-exchanging ATPase activity GO:0005391 8.96 ATP12A ATP4A
2 potassium:proton exchanging ATPase activity GO:0008900 8.62 ATP12A ATP4A

Sources for Acute Laryngitis

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
17 EFO
18 ExPASy
20 FMA
29 GO
30 GTR
31 HGMD
32 HMDB
33 HPO
34 ICD10
35 ICD10 via Orphanet
36 ICD9CM
37 IUPHAR
38 KEGG
39 LifeMap
41 LOVD
43 MedGen
45 MeSH
46 MESH via Orphanet
47 MGI
50 NCI
51 NCIt
52 NDF-RT
55 NINDS
56 Novoseek
58 OMIM
59 OMIM via Orphanet
63 PubMed
65 QIAGEN
70 SNOMED-CT via HPO
71 SNOMED-CT via Orphanet
72 TGDB
73 Tocris
74 UMLS
75 UMLS via Orphanet
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