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MCID: ACT059
MIFTS: 35

Acute Maxillary Sinusitis

Categories: Respiratory diseases
Genes Tissues Related diseases Publications Pathways Drugs
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Aliases & Classifications for Acute Maxillary Sinusitis

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MalaCards integrated aliases for Acute Maxillary Sinusitis:

Name: Acute Maxillary Sinusitis 12 15 71 32
Acute Antritis 12

Classifications:

MalaCards categories:
Anatomical: Respiratory diseases
See all MalaCards categories (disease lists)
ICD10: 32


External Ids:

Disease Ontology 12 DOID:2050
ICD9CM 34 461.0
SNOMED-CT 67 155499007
ICD10 32 J01.0
UMLS 71 C0155804
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Summaries for Acute Maxillary Sinusitis

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Disease Ontology : 12 A maxillary sinusitis which lasts for less than 4 weeks.

MalaCards based summary : Acute Maxillary Sinusitis, also known as acute antritis, is related to bronchitis and disease by infectious agent. An important gene associated with Acute Maxillary Sinusitis is CRP (C-Reactive Protein), and among its related pathways/superpathways is Innate Lymphoid Cell Differentiation Pathways. The drugs Erythromycin and Clarithromycin have been mentioned in the context of this disorder. Affiliated tissues include skin and eye, and related phenotypes are homeostasis/metabolism and immune system

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Related Diseases for Acute Maxillary Sinusitis

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Diseases in the Maxillary Sinusitis family:

Chronic Maxillary Sinusitis Acute Maxillary Sinusitis

Diseases related to Acute Maxillary Sinusitis via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50) (show all 113)
# Related Disease Score Top Affiliating Genes
1 bronchitis 30.1 LTF DNASE1 CRP
2 disease by infectious agent 29.4 PPIG LTA CRP CD8A
3 maxillary sinusitis 11.1
4 haemophilus influenzae 10.7
5 internal hemorrhoid 10.4 NOS2 CRP
6 hemorrhoid 10.4 NOS2 CRP
7 intracranial abscess 10.3 SERPINB4 CRP
8 acquired angioedema 10.3 CRP C3
9 louse-borne relapsing fever 10.3 CRP C3
10 relapsing fever 10.3 CRP C3
11 pyuria 10.3 CRP C3
12 scarlet fever 10.3 CRP C3
13 laryngitis 10.3 DNASE1 CRP
14 mucormycosis 10.3 PPIG CRP
15 acute proliferative glomerulonephritis 10.2 CRP C3
16 acute dacryocystitis 10.2 SERPINB4 DNASE1
17 primary syphilis 10.2 CRP CD8A
18 tertiary syphilis 10.2 CRP CD8A
19 cerebritis 10.2 CRP CD8A
20 granulomatous hepatitis 10.2 CRP CD8A
21 tracheitis 10.2 CRP CD8A
22 viral exanthem 10.2 CRP CD8A
23 secondary syphilis 10.2 CRP CD8A
24 parotid disease 10.2 CRP CD8A
25 neurosarcoidosis 10.2 CRP CD8A
26 scleral disease 10.2 CRP CD8A
27 mononeuropathy 10.2 MPZ CRP
28 miliary tuberculosis 10.2 CRP CD8A
29 duodenitis 10.2 CRP CD8A
30 haemophilus meningitis 10.2 CRP CD8A
31 good syndrome 10.2 CRP CD8A
32 rapidly progressive glomerulonephritis 10.2 CRP C3
33 iritis 10.2 CRP CD8A
34 xerophthalmia 10.2 CRP CD8A
35 cryptogenic organizing pneumonia 10.2 CRP CD8A
36 iridocyclitis 10.2 CRP CD8A
37 chorioretinitis 10.2 CRP CD8A
38 chlamydia pneumonia 10.2 CRP CD8A
39 clostridium difficile colitis 10.2 LTF CRP
40 acute stress disorder 10.2 CRP CD8A
41 hantavirus hemorrhagic fever with renal syndrome 10.2 CRP CD8A
42 lymphangitis 10.2 CRP ALK
43 orbital cellulitis 10.1
44 cellulitis 10.1
45 cluster headache 10.1
46 headache 10.1
47 orchitis 10.1 CRP CD8A
48 urethritis 10.1 CRP CD8A
49 monkeypox 10.1 CD8A C3
50 immunodeficiency with hyper-igm, type 3 10.1 CD8A AICDA

Comorbidity relations with Acute Maxillary Sinusitis via Phenotypic Disease Network (PDN): (show all 11)


Acute Cystitis Acute Ethmoiditis
Acute Frontal Sinusitis Acute Sphenoidal Sinusitis
Bronchitis Chronic Ethmoiditis
Chronic Maxillary Sinusitis Deficiency Anemia
Esophagitis Heart Disease
Hypertension, Essential

Graphical network of the top 20 diseases related to Acute Maxillary Sinusitis:



Diseases related to Acute Maxillary Sinusitis
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Symptoms & Phenotypes for Acute Maxillary Sinusitis

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MGI Mouse Phenotypes related to Acute Maxillary Sinusitis:

46
# Description MGI Source Accession Score Top Affiliating Genes
1 homeostasis/metabolism MP:0005376 9.9 AICDA ALK C3 CRP DNASE1 ERGIC2
2 immune system MP:0005387 9.7 AICDA C3 CD8A CRP DNASE1 LTA
3 mortality/aging MP:0010768 9.36 AICDA ALK BACE2 C3 CD8A DNASE1
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Drugs & Therapeutics for Acute Maxillary Sinusitis

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Drugs for Acute Maxillary Sinusitis (from DrugBank, HMDB, Dgidb, PharmGKB, IUPHAR, NovoSeek, BitterDB):

(show all 12)
# Name Status Phase Clinical Trials Cas Number PubChem Id
1
Erythromycin Approved, Investigational, Vet_approved Phase 4 114-07-8 12560
2
Clarithromycin Approved Phase 4 81103-11-9 84029
3
Azithromycin Approved Phase 4 83905-01-5 55185 447043
4 Antibiotics, Antitubercular Phase 4
5 Erythromycin Estolate Phase 4
6 Anti-Infective Agents Phase 4
7 Erythromycin stearate Phase 4
8 Erythromycin Ethylsuccinate Phase 4
9 Anti-Bacterial Agents Phase 4
10
Ofloxacin Approved Phase 3 82419-36-1 4583
11
Levofloxacin Approved, Investigational Phase 3 100986-85-4 149096
12 Cytochrome P-450 Enzyme Inhibitors Phase 3

Interventional clinical trials:


# Name Status NCT ID Phase Drugs
1 Comparison of Azithromycin or Clarithromycin in 3drugs Protocol of H-pylori Eradication Regimen Completed NCT01667692 Phase 4 azithromycin;clarithmycin
2 An Open-label, Multi-center, Non-comparative Sinus Puncture Study of 750 mg, Short-course Levofloxacin in the Treatment of Acute Maxillary Sinusitis Completed NCT00236652 Phase 3 levofloxacin

Search NIH Clinical Center for Acute Maxillary Sinusitis

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Genetic Tests for Acute Maxillary Sinusitis

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Anatomical Context for Acute Maxillary Sinusitis

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MalaCards organs/tissues related to Acute Maxillary Sinusitis:

40
Skin, Eye
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Publications for Acute Maxillary Sinusitis

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Articles related to Acute Maxillary Sinusitis:

(show top 50) (show all 281)
# Title Authors PMID Year
1
Combined in-person and tele-delivered mobile school clinic: A novel approach for improving access to healthcare during school hours. 61
32393140 2020
2
"Very High-Grade" Pulsatile Mass of an Aberrant Internal Carotid Artery in the Nasopharyngeal Wall: A Case Report and Review of Literature. 61
32282788 2020
3
Premaxillary abscess without bony erosion: An unusual complication of pediatric acute maxillary sinusitis. 61
31427214 2019
4
Nasal nitric oxide is a useful biomarker for acute unilateral maxillary sinusitis in pediatric allergic rhinitis: A prospective observational cohort study. 61
31193296 2019
5
Maxillary sinusitis complicated by stroke. 61
30072286 2018
6
Root Cause Analysis: An Examination of Odontogenic Origins of Acute Maxillary Sinusitis in Both Immunocompetent & Immunocompromised Patients. 61
27798445 2017
7
Are Antibiotics Effective in the Treatment of Acute Maxillary Sinusitis? 61
26498508 2016
8
Management of acute maxillary sinusitis after sinus bone grafting procedures with simultaneous dental implants placement - a retrospective study. 61
27169511 2016
9
Orbital compartment syndrome during endoscopic drainage of subperiosteal orbital abscess. 61
26545481 2015
10
WITHDRAWN: Antibiotics for acute maxillary sinusitis in adults. 61
26471061 2015
11
Acute rhinosinusitis (ARS). Diagnosis and treatment of adults in general practice. 61
24495896 2014
12
Antibiotics for acute maxillary sinusitis in adults. 61
24515610 2014
13
Composite three-layer closure of oral antral communication with 10 months follow-up-a case study. 61
24321311 2014
14
Cluster headache and acute maxillary sinusitis. 61
23381843 2013
15
Chloramphenicol eye drops in the treatment of conditions indicative of maxillary sinusitis. 61
24172626 2013
16
Cluster headache associated with acute maxillary sinusitis. 61
24133652 2013
17
[Characteristics of the course of maxillary sinusitis in children with verified chlamydia infection]. 61
24640716 2013
18
Microbiology of acute and chronic maxillary sinusitis in smokers and nonsmokers. 61
22224311 2011
19
Postoperative maxillary sinusitis mimicking tumor recurrence on positron emission tomography. 61
21346674 2011
20
Radiology quiz case 1. Acute maxillary sinusitis secondary to a migrated dental implant obstructing the ostiomeatal complex. 61
21844418 2011
21
A case of massive maxillary sinus bleeding after dental implant. 61
21377328 2011
22
Presentation and treatment of acute maxillary sinusitis in general practice: a French observational study. 61
21468380 2011
23
[The rationale for the efficacious puncture therapy of acute suppurative sinusitis in the children]. 61
22433682 2011
24
The association between paranasal computerized tomography scans and symptoms and signs in a general practice population with acute maxillary sinusitis. 61
21143525 2011
25
[Features of microflora of nasal mucosa in patients with acute and chronic inflammatory processes of upper respiratory tract during diagnosed Chlamydia infection]. 61
21384593 2010
26
Acute maxillary sinusitis detected by bedside emergency department ultrasonography. 61
21373341 2010
27
Diagnosis and treatment of maxillary sinusitis after implant placement. 61
20386214 2010
28
Symptoms and signs in culture-proven acute maxillary sinusitis in a general practice population. 61
19775340 2009
29
Antibiotics for acute maxillary sinusitis. 61
20141093 2009
30
Frequency of a dental source for acute maxillary sinusitis. 61
19160401 2009
31
Economic evaluation of Sinfrontal in the treatment of acute maxillary sinusitis in adults. 61
19799472 2009
32
Extracts from The Cochrane Library: Antibiotics for acute maxillary sinusitis. 61
18922332 2008
33
Assessment of the bioequivalence of two formulations of clarithromycin extended-release 500-mg tablets under fasting and fed conditions: a single-dose, randomized, open-label, two-period, two-way crossover study in healthy Jordanian male volunteers. 61
19014838 2008
34
Update in infectious disease treatment. 61
18756840 2008
35
Development of maxillary accessory ostium following sinusitis in rabbits. 61
18575013 2008
36
Use of pharmacodynamic endpoints for the evaluation of levofloxacin for the treatment of acute maxillary sinusitis. 61
18313879 2008
37
Commentary on "Use of pharmacodynamic endpoints for the evaluation of levofloxacin for the treatment of acute maxillary sinusitis" by Ambrose et al. 61
18375085 2008
38
Antibiotics for acute maxillary sinusitis. 61
18425861 2008
39
[Pristinamycin use in the treatment of acute maxillary sinusitis in adults]. 61
18342219 2008
40
Acute maxillary sinusitis associated with internal sinus lifting: report of a case. 61
19212512 2008
41
[Major orbital complications of acute maxillary sinusitis of dental aetiology]. 61
19408519 2008
42
Antibiotics and topical nasal steroid for treatment of acute maxillary sinusitis: a randomized controlled trial. 61
18056902 2007
43
Bacteriology of acute rhinosinusitis in nasopharyngeal carcinoma survivors: a result of maxillary sinus punctures. 61
17516077 2007
44
Recommended and prescribed symptomatic treatment for acute maxillary sinusitis in Finnish primary care. 61
17956017 2007
45
Oral garenoxacin in the treatment of acute bacterial maxillary sinusitis: a Phase II, multicenter, noncomparative, open-label study in adult patients undergoing sinus aspiration. 61
17919545 2007
46
Microbiology of acute sinusitis of odontogenic origin presenting with periorbital cellulitis in children. 61
17561769 2007
47
Frequency of recovery of pathogens from the nasopharynx of children with acute maxillary sinusitis before and after the introduction of vaccination with the 7-valent pneumococcal vaccine. 61
17267051 2007
48
Implementing guidelines on acute maxillary sinusitis in general practice--a randomized controlled trial. 61
17237494 2007
49
Efficacy of a complex homeopathic medication (Sinfrontal) in patients with acute maxillary sinusitis: a prospective, randomized, double-blind, placebo-controlled, multicenter clinical trial. 61
17362845 2007
50
Serial sinus aspirate samples during high-dose, short-course levofloxacin treatment of acute maxillary sinusitis. 61
17178300 2007
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Variations for Acute Maxillary Sinusitis

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Expression for Acute Maxillary Sinusitis

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Search GEO for disease gene expression data for Acute Maxillary Sinusitis.
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Pathways for Acute Maxillary Sinusitis

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Pathways related to Acute Maxillary Sinusitis according to GeneCards Suite gene sharing:

# Super pathways Score Top Affiliating Genes
1
Innate Lymphoid Cell Differentiation Pathways 64
10.7 TSLP LTA CD8A
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GO Terms for Acute Maxillary Sinusitis

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Biological processes related to Acute Maxillary Sinusitis according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 innate immune response in mucosa GO:0002227 9.16 NOS2 LTF
2 defense response to Gram-negative bacterium GO:0050829 9.13 TSLP NOS2 LTF
3 negative regulation by host of viral process GO:0044793 8.62 LTF CRP
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Sources for Acute Maxillary Sinusitis

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3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
17 EFO
18 ExPASy
19 FMA
20 GARD
28 GO
29 GTR
30 HMDB
31 HPO
32 ICD10
33 ICD10 via Orphanet
34 ICD9CM
35 IUPHAR
36 KEGG
37 LifeMap
39 LOVD
41 MedGen
44 MeSH
45 MESH via Orphanet
46 MGI
49 NCI
50 NCIt
51 NDF-RT
53 NINDS
54 Novoseek
56 OMIM via Orphanet
57 OMIM® (Updated 05-Mar-2021)
61 PubMed
63 QIAGEN
68 SNOMED-CT via HPO
69 TGDB
70 Tocris
71 UMLS
72 UMLS via Orphanet
The MalaCards human disease database index: 1-9 A B C D E F G H I J K L M N O P Q R S T U V W X Y Z
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