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MCID: ACT059
MIFTS: 35

Acute Maxillary Sinusitis

Categories: Respiratory diseases
Genes Tissues Related diseases Publications Pathways Drugs
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Aliases & Classifications for Acute Maxillary Sinusitis

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MalaCards integrated aliases for Acute Maxillary Sinusitis:

Name: Acute Maxillary Sinusitis 12 15 72 33
Acute Antritis 12

Classifications:

MalaCards categories:
Anatomical: Respiratory diseases
See all MalaCards categories (disease lists)
ICD10: 33


External Ids:

Disease Ontology 12 DOID:2050
ICD9CM 35 461.0
SNOMED-CT 68 18714001 68272006
ICD10 33 J01.0 J01.00
UMLS 72 C0155804
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Summaries for Acute Maxillary Sinusitis

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Disease Ontology : 12 A maxillary sinusitis which lasts for less than 4 weeks.

MalaCards based summary : Acute Maxillary Sinusitis, also known as acute antritis, is related to maxillary sinusitis and haemophilus influenzae. An important gene associated with Acute Maxillary Sinusitis is MAT2A (Methionine Adenosyltransferase 2A), and among its related pathways/superpathways is Warfarin Pathway, Pharmacodynamics. The drugs Clavulanate and Amoxicillin have been mentioned in the context of this disorder. Affiliated tissues include skin, testes and liver, and related phenotype is cardiovascular system.

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Related Diseases for Acute Maxillary Sinusitis

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Diseases in the Maxillary Sinusitis family:

Chronic Maxillary Sinusitis Acute Maxillary Sinusitis

Diseases related to Acute Maxillary Sinusitis via text searches within MalaCards or GeneCards Suite gene sharing:

(show all 41)
# Related Disease Score Top Affiliating Genes
1 maxillary sinusitis 11.1
2 haemophilus influenzae 10.7
3 heel spur 10.3 HCCS CRP
4 xanthogranulomatous pyelonephritis 10.3 HCCS CRP
5 relapsing polychondritis 10.3 MGP CRP
6 acquired angioedema 10.2 CRP C3
7 hypersensitivity vasculitis 10.2 CRP C3
8 hypersensitivity reaction type iii disease 10.1 CRP C3
9 lemierre's syndrome 10.1 CRP C3
10 orbital cellulitis 10.1
11 diarrhea 10.1
12 cellulitis 10.1
13 cluster headache 10.1
14 headache 10.1
15 henoch-schoenlein purpura 10.1 CRP C3
16 yemenite deaf-blind hypopigmentation syndrome 9.9
17 exanthem 9.9
18 osteomyelitis 9.9
19 common cold 9.9
20 chronic maxillary sinusitis 9.9
21 chlamydia 9.9
22 tetanus 9.9
23 urticaria 9.9
24 dental caries 9.9
25 suppurative periapical periodontitis 9.9
26 pleural empyema 9.9
27 rhinitis 9.9
28 bronchitis 9.9
29 ethmoid sinusitis 9.9
30 48,xyyy 9.9
31 odontoma 9.9
32 intussusception 9.9 CRP CD40LG
33 bladder disease 9.8 PPIG CRP
34 pelvic inflammatory disease 9.8 CRP CD40LG
35 brucellosis 9.7 CRP CD40LG
36 anemia, autoimmune hemolytic 9.7 CD40LG C3
37 autoimmune disease of musculoskeletal system 9.5 CRP CD40LG C3
38 lyme disease 9.4 CRP CD40LG C3
39 kidney disease 9.4 MGP CRP C3
40 systemic scleroderma 9.4 CRP CD40LG
41 systemic lupus erythematosus 8.9 GAS6 CRP CD40LG C3

Comorbidity relations with Acute Maxillary Sinusitis via Phenotypic Disease Network (PDN): (show all 11)


Acute Cystitis Acute Ethmoiditis
Acute Frontal Sinusitis Acute Sphenoidal Sinusitis
Bronchitis Chronic Ethmoiditis
Chronic Maxillary Sinusitis Deficiency Anemia
Esophagitis Heart Disease
Hypertension, Essential

Graphical network of the top 20 diseases related to Acute Maxillary Sinusitis:



Diseases related to Acute Maxillary Sinusitis
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Symptoms & Phenotypes for Acute Maxillary Sinusitis

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MGI Mouse Phenotypes related to Acute Maxillary Sinusitis:

46
# Description MGI Source Accession Score Top Affiliating Genes
1 cardiovascular system MP:0005385 9.1 C3 CD40LG CRP GAS6 HCCS MGP
Sources

Drugs & Therapeutics for Acute Maxillary Sinusitis

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Drugs for Acute Maxillary Sinusitis (from DrugBank, HMDB, Dgidb, PharmGKB, IUPHAR, NovoSeek, BitterDB):

(show all 24)
# Name Status Phase Clinical Trials Cas Number PubChem Id
1
Clavulanate Approved, Vet_approved Phase 4 58001-44-8 5280980
2
Amoxicillin Approved, Vet_approved Phase 4 26787-78-0 33613
3 Strawberry Approved Phase 4
4
Clarithromycin Approved Phase 4 81103-11-9 84029
5
Erythromycin Approved, Investigational, Vet_approved Phase 4 114-07-8 441411 12560
6
Telithromycin Approved Phase 4 191114-48-4 5462516 70789201
7
Azithromycin Approved Phase 4 83905-01-5 447043 55185
8 Amoxicillin-Potassium Clavulanate Combination Phase 4
9 beta-Lactamase Inhibitors Phase 4
10 Cytochrome P-450 Enzyme Inhibitors Phase 4
11 Cytochrome P-450 CYP3A Inhibitors Phase 4
12 Antitubercular Agents Phase 4
13 Erythromycin Ethylsuccinate Phase 4
14 Erythromycin stearate Phase 4
15 Erythromycin Estolate Phase 4
16 Anti-Bacterial Agents Phase 4
17 Antibiotics, Antitubercular Phase 4
18 Anti-Infective Agents Phase 4
19
Ofloxacin Approved Phase 3 82419-36-1 4583
20
Levofloxacin Approved, Investigational Phase 3 100986-85-4 149096
21 Renal Agents Phase 3
22 Topoisomerase Inhibitors Phase 3
23 Cytochrome P-450 CYP1A2 Inhibitors Phase 3
24 Anti-Infective Agents, Urinary Phase 3

Interventional clinical trials:


# Name Status NCT ID Phase Drugs
1 Clinical Relevance of Middle Meatal Bacteriology During Acute Respiratory Infection in Children - Randomised, Double-Blinded Clinical Study Unknown status NCT00545961 Phase 4 placebo;amoxicillin clavulanate acid
2 Comparison of Azithromycin or Clarithromycin in 3drugs Protocol of H-pylori Eradication Regimen Completed NCT01667692 Phase 4 azithromycin;clarithmycin
3 Influence of Oral Telithromycin vs. Azithromycin on the Endogenous Microflora in Adults With Acute Sinusitis Terminated NCT00245440 Phase 4 Azithromycin;Telithromycin
4 An Open-label, Multi-center, Non-comparative Sinus Puncture Study of 750 mg, Short-course Levofloxacin in the Treatment of Acute Maxillary Sinusitis Completed NCT00236652 Phase 3 levofloxacin

Search NIH Clinical Center for Acute Maxillary Sinusitis

Inferred drug relations via UMLS 72 / NDF-RT 51 :


Cefpodoxime
Clarithromycin
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Genetic Tests for Acute Maxillary Sinusitis

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Anatomical Context for Acute Maxillary Sinusitis

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MalaCards organs/tissues related to Acute Maxillary Sinusitis:

41
Skin, Testes, Liver, Bone, Eye
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Publications for Acute Maxillary Sinusitis

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Articles related to Acute Maxillary Sinusitis:

(show top 50) (show all 279)
# Title Authors PMID Year
1
Premaxillary abscess without bony erosion: An unusual complication of pediatric acute maxillary sinusitis. 38
31427214 2019
2
Nasal nitric oxide is a useful biomarker for acute unilateral maxillary sinusitis in pediatric allergic rhinitis: A prospective observational cohort study. 38
31193296 2019
3
Maxillary sinusitis complicated by stroke. 38
30072286 2018
4
Root Cause Analysis: An Examination of Odontogenic Origins of Acute Maxillary Sinusitis in Both Immunocompetent & Immunocompromised Patients. 38
27798445 2017
5
Management of acute maxillary sinusitis after sinus bone grafting procedures with simultaneous dental implants placement - a retrospective study. 38
27169511 2016
6
Are Antibiotics Effective in the Treatment of Acute Maxillary Sinusitis? 38
26498508 2016
7
Orbital compartment syndrome during endoscopic drainage of subperiosteal orbital abscess. 38
26545481 2015
8
WITHDRAWN: Antibiotics for acute maxillary sinusitis in adults. 38
26471061 2015
9
Antibiotics for acute maxillary sinusitis in adults. 38
24515610 2014
10
Composite three-layer closure of oral antral communication with 10 months follow-up-a case study. 38
24321311 2014
11
Acute rhinosinusitis (ARS). Diagnosis and treatment of adults in general practice. 38
24495896 2014
12
Cluster headache and acute maxillary sinusitis. 38
23381843 2013
13
Chloramphenicol eye drops in the treatment of conditions indicative of maxillary sinusitis. 38
24172626 2013
14
Cluster headache associated with acute maxillary sinusitis. 38
24133652 2013
15
[Characteristics of the course of maxillary sinusitis in children with verified chlamydia infection]. 38
24640716 2013
16
Microbiology of acute and chronic maxillary sinusitis in smokers and nonsmokers. 38
22224311 2011
17
Postoperative maxillary sinusitis mimicking tumor recurrence on positron emission tomography. 38
21346674 2011
18
Radiology quiz case 1. Acute maxillary sinusitis secondary to a migrated dental implant obstructing the ostiomeatal complex. 38
21844418 2011
19
A case of massive maxillary sinus bleeding after dental implant. 38
21377328 2011
20
Presentation and treatment of acute maxillary sinusitis in general practice: a French observational study. 38
21468380 2011
21
The association between paranasal computerized tomography scans and symptoms and signs in a general practice population with acute maxillary sinusitis. 38
21143525 2011
22
[The rationale for the efficacious puncture therapy of acute suppurative sinusitis in the children]. 38
22433682 2011
23
[Features of microflora of nasal mucosa in patients with acute and chronic inflammatory processes of upper respiratory tract during diagnosed Chlamydia infection]. 38
21384593 2010
24
Acute maxillary sinusitis detected by bedside emergency department ultrasonography. 38
21373341 2010
25
Diagnosis and treatment of maxillary sinusitis after implant placement. 38
20386214 2010
26
Symptoms and signs in culture-proven acute maxillary sinusitis in a general practice population. 38
19775340 2009
27
Antibiotics for acute maxillary sinusitis. 38
20141093 2009
28
Frequency of a dental source for acute maxillary sinusitis. 38
19160401 2009
29
Economic evaluation of Sinfrontal in the treatment of acute maxillary sinusitis in adults. 38
19799472 2009
30
Extracts from The Cochrane Library: Antibiotics for acute maxillary sinusitis. 38
18922332 2008
31
Assessment of the bioequivalence of two formulations of clarithromycin extended-release 500-mg tablets under fasting and fed conditions: a single-dose, randomized, open-label, two-period, two-way crossover study in healthy Jordanian male volunteers. 38
19014838 2008
32
Update in infectious disease treatment. 38
18756840 2008
33
Development of maxillary accessory ostium following sinusitis in rabbits. 38
18575013 2008
34
Use of pharmacodynamic endpoints for the evaluation of levofloxacin for the treatment of acute maxillary sinusitis. 38
18313879 2008
35
Commentary on "Use of pharmacodynamic endpoints for the evaluation of levofloxacin for the treatment of acute maxillary sinusitis" by Ambrose et al. 38
18375085 2008
36
Antibiotics for acute maxillary sinusitis. 38
18425861 2008
37
[Pristinamycin use in the treatment of acute maxillary sinusitis in adults]. 38
18342219 2008
38
Acute maxillary sinusitis associated with internal sinus lifting: report of a case. 38
19212512 2008
39
[Major orbital complications of acute maxillary sinusitis of dental aetiology]. 38
19408519 2008
40
Antibiotics and topical nasal steroid for treatment of acute maxillary sinusitis: a randomized controlled trial. 38
18056902 2007
41
Bacteriology of acute rhinosinusitis in nasopharyngeal carcinoma survivors: a result of maxillary sinus punctures. 38
17516077 2007
42
Recommended and prescribed symptomatic treatment for acute maxillary sinusitis in Finnish primary care. 38
17956017 2007
43
Oral garenoxacin in the treatment of acute bacterial maxillary sinusitis: a Phase II, multicenter, noncomparative, open-label study in adult patients undergoing sinus aspiration. 38
17919545 2007
44
Microbiology of acute sinusitis of odontogenic origin presenting with periorbital cellulitis in children. 38
17561769 2007
45
Implementing guidelines on acute maxillary sinusitis in general practice--a randomized controlled trial. 38
17237494 2007
46
Frequency of recovery of pathogens from the nasopharynx of children with acute maxillary sinusitis before and after the introduction of vaccination with the 7-valent pneumococcal vaccine. 38
17267051 2007
47
Efficacy of a complex homeopathic medication (Sinfrontal) in patients with acute maxillary sinusitis: a prospective, randomized, double-blind, placebo-controlled, multicenter clinical trial. 38
17362845 2007
48
Serial sinus aspirate samples during high-dose, short-course levofloxacin treatment of acute maxillary sinusitis. 38
17178300 2007
49
Frequency of recovery of pathogens causing acute maxillary sinusitis in adults before and after introduction of vaccination of children with the 7-valent pneumococcal vaccine. 38
16772423 2006
50
Macrolide immunomodulatory effects and symptom resolution in acute exacerbation of chronic bronchitis and acute maxillary sinusitis: a focus on clarithromycin. 38
16771618 2006
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Variations for Acute Maxillary Sinusitis

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Expression for Acute Maxillary Sinusitis

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Search GEO for disease gene expression data for Acute Maxillary Sinusitis.
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Pathways for Acute Maxillary Sinusitis

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Pathways related to Acute Maxillary Sinusitis according to GeneCards Suite gene sharing:

# Super pathways Score Top Affiliating Genes
1
Warfarin Pathway, Pharmacodynamics 61
9.8 MGP GAS6
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GO Terms for Acute Maxillary Sinusitis

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Biological processes related to Acute Maxillary Sinusitis according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 inflammatory response GO:0006954 9.13 CRP CD40LG C3
2 positive regulation of phagocytosis GO:0050766 8.62 GAS6 C3
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Sources for Acute Maxillary Sinusitis

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3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
17 EFO
18 ExPASy
19 FMA
28 GO
29 GTR
30 HGMD
31 HMDB
32 HPO
33 ICD10
34 ICD10 via Orphanet
35 ICD9CM
36 IUPHAR
37 KEGG
38 LifeMap
40 LOVD
42 MedGen
44 MeSH
45 MESH via Orphanet
46 MGI
49 NCI
50 NCIt
51 NDF-RT
54 NINDS
55 Novoseek
57 OMIM
58 OMIM via Orphanet
62 PubMed
64 QIAGEN
69 SNOMED-CT via HPO
70 TGDB
71 Tocris
72 UMLS
73 UMLS via Orphanet
The MalaCards human disease database index: 1-9 A B C D E F G H I J K L M N O P Q R S T U V W X Y Z
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