MCID: ACT059
MIFTS: 33

Acute Maxillary Sinusitis

Categories: Respiratory diseases

Aliases & Classifications for Acute Maxillary Sinusitis

MalaCards integrated aliases for Acute Maxillary Sinusitis:

Name: Acute Maxillary Sinusitis 12 15 74
Acute Antritis 12

Classifications:



External Ids:

Disease Ontology 12 DOID:2050
ICD9CM 36 461.0
SNOMED-CT 69 18714001 68272006
ICD10 34 J01.0 J01.00
UMLS 74 C0155804

Summaries for Acute Maxillary Sinusitis

Disease Ontology : 12 A maxillary sinusitis which lasts for less than 4 weeks.

MalaCards based summary : Acute Maxillary Sinusitis, also known as acute antritis, is related to sinusitis and maxillary sinusitis. An important gene associated with Acute Maxillary Sinusitis is MAT2A (Methionine Adenosyltransferase 2A), and among its related pathways/superpathways are Gamma carboxylation, hypusine formation and arylsulfatase activation and Warfarin Pathway, Pharmacodynamics. The drugs Biaxin XL and Erythromycin have been mentioned in the context of this disorder. Affiliated tissues include testes, skin and tonsil, and related phenotype is cardiovascular system.

Related Diseases for Acute Maxillary Sinusitis

Graphical network of the top 20 diseases related to Acute Maxillary Sinusitis:



Diseases related to Acute Maxillary Sinusitis

Symptoms & Phenotypes for Acute Maxillary Sinusitis

MGI Mouse Phenotypes related to Acute Maxillary Sinusitis:

47
# Description MGI Source Accession Score Top Affiliating Genes
1 cardiovascular system MP:0005385 9.02 C3 CRP F9 GAS6 HCCS

Drugs & Therapeutics for Acute Maxillary Sinusitis

FDA approved drugs:

# Drug Name Active Ingredient(s) 19 Company Approval Date
1
Biaxin XL 19 CLARITHROMYCIN Abbott Laboratories March 2000

Drugs for Acute Maxillary Sinusitis (from DrugBank, HMDB, Dgidb, PharmGKB, IUPHAR, NovoSeek, BitterDB):

(show all 19)
# Name Status Phase Clinical Trials Cas Number PubChem Id
1
Erythromycin Approved, Investigational, Vet_approved Phase 4 114-07-8 12560 441411
2
Azithromycin Approved Phase 4 83905-01-5 55185 447043
3
Clarithromycin Approved Phase 4 81103-11-9 84029
4
Telithromycin Approved Phase 4 191114-48-4 70789201 5462516
5 Cytochrome P-450 Enzyme Inhibitors Phase 4,Phase 3
6 Anti-Bacterial Agents Phase 4,Phase 3
7 Cytochrome P-450 CYP3A Inhibitors Phase 4
8 Erythromycin stearate Phase 4
9 Anti-Infective Agents Phase 4,Phase 3
10 Antibiotics, Antitubercular Phase 4
11 Antitubercular Agents Phase 4
12 Erythromycin Estolate Phase 4
13 Erythromycin Ethylsuccinate Phase 4
14
Ofloxacin Approved Phase 3 82419-36-1 4583
15
Levofloxacin Approved, Investigational Phase 3 100986-85-4 149096
16 Cytochrome P-450 CYP1A2 Inhibitors Phase 3
17 Anti-Infective Agents, Urinary Phase 3
18 Topoisomerase Inhibitors Phase 3
19 Renal Agents Phase 3

Interventional clinical trials:


# Name Status NCT ID Phase Drugs
1 Aizthromycin or Clarithromycin in H-pylori Eradication Regimen Completed NCT01667692 Phase 4 azithromycin;clarithmycin
2 Study to Measure the Impact of Antibiotics on Bacterial Flora in Adults With Acute Sinusitis Terminated NCT00245440 Phase 4 Azithromycin;Telithromycin
3 A Study Evaluating the Safety and Efficacy of Treating Sinus Infection With Levofloxacin 750 mg for 5 Days. Completed NCT00236652 Phase 3 levofloxacin

Search NIH Clinical Center for Acute Maxillary Sinusitis

Genetic Tests for Acute Maxillary Sinusitis

Anatomical Context for Acute Maxillary Sinusitis

MalaCards organs/tissues related to Acute Maxillary Sinusitis:

42
Testes, Skin, Tonsil, Bone

Publications for Acute Maxillary Sinusitis

Articles related to Acute Maxillary Sinusitis:

(show top 50) (show all 133)
# Title Authors Year
1
Root Cause Analysis: An Examination of Odontogenic Origins of Acute Maxillary Sinusitis in Both Immunocompetent & Immunocompromised Patients. ( 27798445 )
2016
2
Management of acute maxillary sinusitis after sinus bone grafting procedures with simultaneous dental implants placement - a retrospective study. ( 27169511 )
2016
3
WITHDRAWN: Antibiotics for acute maxillary sinusitis in adults. ( 26471061 )
2015
4
Antibiotics for acute maxillary sinusitis in adults. ( 24515610 )
2014
5
Cluster headache and acute maxillary sinusitis. ( 23381843 )
2013
6
Cluster headache associated with acute maxillary sinusitis. ( 24133652 )
2013
7
The association between paranasal computerized tomography scans and symptoms and signs in a general practice population with acute maxillary sinusitis. ( 21143525 )
2011
8
Presentation and treatment of acute maxillary sinusitis in general practice: a French observational study. ( 21468380 )
2011
9
Radiology quiz case 1. Acute maxillary sinusitis secondary to a migrated dental implant obstructing the ostiomeatal complex. ( 21844418 )
2011
10
Acute maxillary sinusitis detected by bedside emergency department ultrasonography. ( 21373341 )
2010
11
Economic evaluation of Sinfrontal in the treatment of acute maxillary sinusitis in adults. ( 19799472 )
2009
12
Antibiotics for acute maxillary sinusitis. ( 20141093 )
2009
13
Frequency of a dental source for acute maxillary sinusitis. ( 19160401 )
2009
14
Symptoms and signs in culture-proven acute maxillary sinusitis in a general practice population. ( 19775340 )
2009
15
Commentary on "Use of pharmacodynamic endpoints for the evaluation of levofloxacin for the treatment of acute maxillary sinusitis" by Ambrose et al. ( 18375085 )
2008
16
Antibiotics for acute maxillary sinusitis. ( 18425861 )
2008
17
Acute maxillary sinusitis associated with internal sinus lifting: report of a case. ( 19212512 )
2008
18
Extracts from The Cochrane Library: Antibiotics for acute maxillary sinusitis. ( 18922332 )
2008
19
Use of pharmacodynamic endpoints for the evaluation of levofloxacin for the treatment of acute maxillary sinusitis. ( 18313879 )
2008
20
Recommended and prescribed symptomatic treatment for acute maxillary sinusitis in Finnish primary care. ( 17956017 )
2007
21
Implementing guidelines on acute maxillary sinusitis in general practice--a randomized controlled trial. ( 17237494 )
2007
22
Antibiotics and topical nasal steroid for treatment of acute maxillary sinusitis: a randomized controlled trial. ( 18056902 )
2007
23
Efficacy of a complex homeopathic medication (Sinfrontal) in patients with acute maxillary sinusitis: a prospective, randomized, double-blind, placebo-controlled, multicenter clinical trial. ( 17362845 )
2007
24
Serial sinus aspirate samples during high-dose, short-course levofloxacin treatment of acute maxillary sinusitis. ( 17178300 )
2007
25
Frequency of recovery of pathogens from the nasopharynx of children with acute maxillary sinusitis before and after the introduction of vaccination with the 7-valent pneumococcal vaccine. ( 17267051 )
2007
26
Frequency of recovery of pathogens causing acute maxillary sinusitis in adults before and after introduction of vaccination of children with the 7-valent pneumococcal vaccine. ( 16772423 )
2006
27
Effect of telithromycin and azithromycin on nasopharyngeal bacterial flora in patients with acute maxillary sinusitis. ( 16618915 )
2006
28
Macrolide immunomodulatory effects and symptom resolution in acute exacerbation of chronic bronchitis and acute maxillary sinusitis: a focus on clarithromycin. ( 16771618 )
2006
29
Bacteriological efficacy of 5-day therapy with telithromycin in acute maxillary sinusitis. ( 15737519 )
2005
30
Current position of the management of community-acquired acute maxillary sinusitis or rhinosinusitis in France and literature review. ( 16405280 )
2005
31
Recovery of interfering bacteria in the nasopharynx following antimicrobial therapy of acute maxillary sinusitis with telithromycin or amoxicillin-clavulanate. ( 16251334 )
2005
32
Eradication of pathogens from the nasopharynx after therapy of acute maxillary sinusitis with low- or high-dose amoxicillin/clavulanic acid. ( 16226017 )
2005
33
Clinical and bacteriological efficacy of 5-day telithromycin in acute maxillary sinusitis: a pooled analysis. ( 15780415 )
2005
34
Use of pharmacodynamic end points in the evaluation of gatifloxacin for the treatment of acute maxillary sinusitis. ( 15156435 )
2004
35
Antimicrobial resistance in the nasopharyngeal flora of children with acute maxillary sinusitis and maxillary sinusitis recurring after amoxicillin therapy. ( 14729759 )
2004
36
Management of acute maxillary sinusitis in Finnish primary care. Results from the nationwide MIKSTRA study. ( 15255494 )
2004
37
Patients' and physicians' views on the management of acute maxillary sinusitis. ( 15119516 )
2004
38
Antibiotics for acute maxillary sinusitis. ( 12804392 )
2003
39
Efficacy and tolerability of telithromycin for 5 or 10 days vs amoxicillin/clavulanic acid for 10 days in acute maxillary sinusitis. ( 14503094 )
2003
40
Evidence-based emergency medicine/systematic review abstract: Antibiotic treatment for acute maxillary sinusitis. ( 14581925 )
2003
41
Clinical inquiries. Are antibiotics helpful for acute maxillary sinusitis? ( 12791232 )
2003
42
Moxifloxacin in the treatment of acute maxillary sinusitis after first-line treatment failure and acute sinusitis with high risk of complications. ( 14587313 )
2003
43
The treatment duration of acute maxillary sinusitis: how long should it be? A nasal smear controlled study. ( 12526248 )
2002
44
Diagnostic accuracy of acute maxillary sinusitis in adults in primary care. ( 12086283 )
2002
45
Efficacy and tolerability of once-daily therapy with telithromycin for 5 or 10 days for the treatment of acute maxillary sinusitis. ( 12011543 )
2002
46
Moxifloxacin versus amoxicillin clavulanate in the treatment of acute maxillary sinusitis: a primary care experience. ( 11452678 )
2001
47
Phase III, randomized, double-blind study of clarithromycin extended-release and immediate-release formulations in the treatment of adult patients with acute maxillary sinusitis. ( 11192134 )
2000
48
Which antibiotics lead to higher clinical cure rates in adults with acute maxillary sinusitis? ( 10903293 )
2000
49
Comparison of ultrasound, radiography, and clinical examination in the diagnosis of acute maxillary sinusitis: a systematic review. ( 11004420 )
2000
50
Antibiotics for acute maxillary sinusitis. ( 10796515 )
2000

Variations for Acute Maxillary Sinusitis

Expression for Acute Maxillary Sinusitis

Search GEO for disease gene expression data for Acute Maxillary Sinusitis.

Pathways for Acute Maxillary Sinusitis

GO Terms for Acute Maxillary Sinusitis

Cellular components related to Acute Maxillary Sinusitis according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 Golgi lumen GO:0005796 8.96 F9 GAS6
2 endoplasmic reticulum lumen GO:0005788 8.8 C3 F9 GAS6

Biological processes related to Acute Maxillary Sinusitis according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 positive regulation of phagocytosis GO:0050766 8.62 C3 GAS6

Molecular functions related to Acute Maxillary Sinusitis according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 metal ion binding GO:0046872 9.1 BAZ2A CRP F9 GAS6 HCCS MAT2A

Sources for Acute Maxillary Sinusitis

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
17 EFO
18 ExPASy
20 FMA
29 GO
30 GTR
31 HGMD
32 HMDB
33 HPO
34 ICD10
35 ICD10 via Orphanet
36 ICD9CM
37 IUPHAR
38 KEGG
39 LifeMap
41 LOVD
43 MedGen
45 MeSH
46 MESH via Orphanet
47 MGI
50 NCI
51 NCIt
52 NDF-RT
55 NINDS
56 Novoseek
58 OMIM
59 OMIM via Orphanet
63 PubMed
65 QIAGEN
70 SNOMED-CT via HPO
71 SNOMED-CT via Orphanet
72 TGDB
73 Tocris
74 UMLS
75 UMLS via Orphanet
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