MCID: ACT059
MIFTS: 38

Acute Maxillary Sinusitis

Categories: Respiratory diseases

Aliases & Classifications for Acute Maxillary Sinusitis

MalaCards integrated aliases for Acute Maxillary Sinusitis:

Name: Acute Maxillary Sinusitis 12 15 73
Acute Antritis 12

Classifications:



External Ids:

Disease Ontology 12 DOID:2050
ICD10 33 J01.0 J01.00
ICD9CM 35 461.0
UMLS 73 C0155804

Summaries for Acute Maxillary Sinusitis

Disease Ontology : 12 A maxillary sinusitis which lasts for less than 4 weeks.

MalaCards based summary : Acute Maxillary Sinusitis, also known as acute antritis, is related to sinusitis and maxillary sinusitis. An important gene associated with Acute Maxillary Sinusitis is MAT2A (Methionine Adenosyltransferase 2A), and among its related pathways/superpathways are Primary immunodeficiency and Warfarin Pathway, Pharmacodynamics. The drugs Biaxin XL and Azithromycin have been mentioned in the context of this disorder. Affiliated tissues include testes, tonsil and skin, and related phenotypes are cardiovascular system and immune system

Related Diseases for Acute Maxillary Sinusitis

Diseases in the Maxillary Sinusitis family:

Chronic Maxillary Sinusitis Acute Maxillary Sinusitis

Diseases related to Acute Maxillary Sinusitis via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50) (show all 190)
# Related Disease Score Top Affiliating Genes
1 sinusitis 10.9
2 maxillary sinusitis 10.9
3 heel spur 10.7 CRP HCCS
4 xanthogranulomatous pyelonephritis 10.6 CRP HCCS
5 acquired angioedema 10.6 C3 CRP
6 acalculous cholecystitis 10.6 CD40LG CRP
7 mononeuritis multiplex 10.6 CD40LG CRP
8 japanese spotted fever 10.5 CD40LG CRP
9 suppurative otitis media 10.5 CD40LG CRP
10 epididymitis 10.5 CD40LG CRP
11 dressler's syndrome 10.5 CD40LG CRP
12 central nervous system vasculitis 10.5 CD40LG CRP
13 lemierre's syndrome 10.5 C3 CRP
14 skeletal tuberculosis 10.5 CRP F9
15 streptococcal meningitis 10.5 CD40LG CRP
16 scrub typhus 10.4 CD40LG CRP
17 la crosse encephalitis 10.4 CD40LG GAS6
18 dirofilariasis 10.4 CD40LG CRP
19 multiple cranial nerve palsy 10.4 CD40LG CRP
20 pelvic inflammatory disease 10.4 CD40LG CRP
21 hemorrhagic fever with renal syndrome 10.4 CD40LG CRP
22 leptospirosis 10.3 CD40LG CRP
23 lymphatic system disease 10.2 CD40LG CRP
24 intestinal tuberculosis 10.2 CD79A CRP
25 brucellosis 10.2 CD40LG CRP
26 bladder disease 10.2 CRP PPIG
27 rapidly progressive glomerulonephritis 10.2 CD79A CRP
28 blood coagulation disease 10.1 CD40LG F9
29 leukocyte disease 10.1 CD40LG CRP
30 mesangial proliferative glomerulonephritis 10.1 CD79A GAS6
31 focal dermal hypoplasia 10.1 CD79A HCCS
32 dysentery 10.1 CD79A CRP
33 selective igg deficiency disease 10.0 CD40LG CD79A
34 c1q nephropathy 10.0 CD40LG CD79A
35 meningovascular neurosyphilis 10.0 CD40LG CD79A
36 alpha chain disease 10.0 CD40LG CD79A
37 brill-zinsser disease 10.0 CD40LG CD79A
38 exudative glomerulonephritis 10.0 CD40LG CD79A
39 cork-handlers' disease 10.0 CD40LG CD79A
40 salpingo-oophoritis 10.0 CD40LG CD79A
41 early yaws 10.0 CD40LG CD79A
42 ventilation pneumonitis 10.0 CD40LG CD79A
43 chronic interstitial cystitis 10.0 CD40LG CD79A
44 axillary adenitis 10.0 CD40LG CD79A
45 cryofibrinogenemia 10.0 CD40LG CD79A
46 trichostrongyloidiasis 10.0 CD40LG CD79A
47 subacute bacterial endocarditis 10.0 CD40LG CD79A
48 heterophyiasis 10.0 CD40LG CD79A
49 immunoglobulin g deficiency 10.0 CD40LG CD79A
50 orbital granuloma 10.0 CD40LG CD79A

Comorbidity relations with Acute Maxillary Sinusitis via Phenotypic Disease Network (PDN): (show all 11)


Acute Cystitis Acute Ethmoiditis
Acute Frontal Sinusitis Acute Sphenoidal Sinusitis
Bronchitis Chronic Ethmoiditis
Chronic Maxillary Sinusitis Deficiency Anemia
Esophagitis Heart Disease
Hypertension, Essential

Graphical network of the top 20 diseases related to Acute Maxillary Sinusitis:



Diseases related to Acute Maxillary Sinusitis

Symptoms & Phenotypes for Acute Maxillary Sinusitis

MGI Mouse Phenotypes related to Acute Maxillary Sinusitis:

46
# Description MGI Source Accession Score Top Affiliating Genes
1 cardiovascular system MP:0005385 9.43 C3 CD40LG CRP F9 GAS6 HCCS
2 immune system MP:0005387 9.17 C3 CD40LG CD79A CRP F9 GAS6

Drugs & Therapeutics for Acute Maxillary Sinusitis

FDA approved drugs:

# Drug Name Active Ingredient(s) 18 Company Approval Date
1
Biaxin XL 18 CLARITHROMYCIN Abbott Laboratories March 2000

Drugs for Acute Maxillary Sinusitis (from DrugBank, HMDB, Dgidb, PharmGKB, IUPHAR, NovoSeek, BitterDB):

(show all 18)
# Name Status Phase Clinical Trials Cas Number PubChem Id
1
Azithromycin Approved Phase 4 83905-01-5 55185 447043
2
Clarithromycin Approved Phase 4 81103-11-9 84029
3
Erythromycin Approved, Investigational, Vet_approved Phase 4 114-07-8 12560
4
Telithromycin Approved Phase 4 191114-48-4 5462516 0
5 Anti-Bacterial Agents Phase 4,Phase 3
6 Antibiotics, Antitubercular Phase 4
7 Anti-Infective Agents Phase 4,Phase 3
8 Antitubercular Agents Phase 4
9 Cytochrome P-450 CYP3A Inhibitors Phase 4
10 Cytochrome P-450 Enzyme Inhibitors Phase 4,Phase 3
11 Erythromycin Estolate Phase 4
12 Erythromycin Ethylsuccinate Phase 4
13 Erythromycin stearate Phase 4
14
Levofloxacin Approved, Investigational Phase 3 100986-85-4 149096
15
Ofloxacin Approved Phase 3 82419-36-1 4583
16 Cytochrome P-450 CYP1A2 Inhibitors Phase 3
17 Renal Agents Phase 3
18 Topoisomerase Inhibitors Phase 3

Interventional clinical trials:


# Name Status NCT ID Phase Drugs
1 Aizthromycin or Clarithromycin in H-pylori Eradication Regimen Completed NCT01667692 Phase 4 azithromycin;clarithmycin
2 Study to Measure the Impact of Antibiotics on Bacterial Flora in Adults With Acute Sinusitis Terminated NCT00245440 Phase 4 Azithromycin;Telithromycin
3 A Study Evaluating the Safety and Efficacy of Treating Sinus Infection With Levofloxacin 750 mg for 5 Days. Completed NCT00236652 Phase 3 levofloxacin

Search NIH Clinical Center for Acute Maxillary Sinusitis

Genetic Tests for Acute Maxillary Sinusitis

Anatomical Context for Acute Maxillary Sinusitis

MalaCards organs/tissues related to Acute Maxillary Sinusitis:

41
Testes, Tonsil, Skin, Bone

Publications for Acute Maxillary Sinusitis

Articles related to Acute Maxillary Sinusitis:

(show top 50) (show all 130)
# Title Authors Year
1
Root Cause Analysis: An Examination of Odontogenic Origins of Acute Maxillary Sinusitis in Both Immunocompetent & Immunocompromised Patients. ( 27798445 )
2016
2
Management of acute maxillary sinusitis after sinus bone grafting procedures with simultaneous dental implants placement - a retrospective study. ( 27169511 )
2016
3
WITHDRAWN: Antibiotics for acute maxillary sinusitis in adults. ( 26471061 )
2015
4
Antibiotics for acute maxillary sinusitis in adults. ( 24515610 )
2014
5
Cluster headache and acute maxillary sinusitis. ( 23381843 )
2013
6
Cluster headache associated with acute maxillary sinusitis. ( 24133652 )
2013
7
The association between paranasal computerized tomography scans and symptoms and signs in a general practice population with acute maxillary sinusitis. ( 21143525 )
2011
8
Presentation and treatment of acute maxillary sinusitis in general practice: a French observational study. ( 21468380 )
2011
9
Radiology quiz case 1. Acute maxillary sinusitis secondary to a migrated dental implant obstructing the ostiomeatal complex. ( 21844418 )
2011
10
Acute maxillary sinusitis detected by bedside emergency department ultrasonography. ( 21373341 )
2010
11
Economic evaluation of Sinfrontal in the treatment of acute maxillary sinusitis in adults. ( 19799472 )
2009
12
Antibiotics for acute maxillary sinusitis. ( 20141093 )
2009
13
Frequency of a dental source for acute maxillary sinusitis. ( 19160401 )
2009
14
Symptoms and signs in culture-proven acute maxillary sinusitis in a general practice population. ( 19775340 )
2009
15
Antibiotics for acute maxillary sinusitis. ( 18425861 )
2008
16
Acute maxillary sinusitis associated with internal sinus lifting: report of a case. ( 19212512 )
2008
17
Extracts from The Cochrane Library: Antibiotics for acute maxillary sinusitis. ( 18922332 )
2008
18
Use of pharmacodynamic endpoints for the evaluation of levofloxacin for the treatment of acute maxillary sinusitis. ( 18313879 )
2008
19
Recommended and prescribed symptomatic treatment for acute maxillary sinusitis in Finnish primary care. ( 17956017 )
2007
20
Implementing guidelines on acute maxillary sinusitis in general practice--a randomized controlled trial. ( 17237494 )
2007
21
Antibiotics and topical nasal steroid for treatment of acute maxillary sinusitis: a randomized controlled trial. ( 18056902 )
2007
22
Efficacy of a complex homeopathic medication (Sinfrontal) in patients with acute maxillary sinusitis: a prospective, randomized, double-blind, placebo-controlled, multicenter clinical trial. ( 17362845 )
2007
23
Serial sinus aspirate samples during high-dose, short-course levofloxacin treatment of acute maxillary sinusitis. ( 17178300 )
2007
24
Frequency of recovery of pathogens from the nasopharynx of children with acute maxillary sinusitis before and after the introduction of vaccination with the 7-valent pneumococcal vaccine. ( 17267051 )
2007
25
Frequency of recovery of pathogens causing acute maxillary sinusitis in adults before and after introduction of vaccination of children with the 7-valent pneumococcal vaccine. ( 16772423 )
2006
26
Effect of telithromycin and azithromycin on nasopharyngeal bacterial flora in patients with acute maxillary sinusitis. ( 16618915 )
2006
27
Macrolide immunomodulatory effects and symptom resolution in acute exacerbation of chronic bronchitis and acute maxillary sinusitis: a focus on clarithromycin. ( 16771618 )
2006
28
Bacteriological efficacy of 5-day therapy with telithromycin in acute maxillary sinusitis. ( 15737519 )
2005
29
Current position of the management of community-acquired acute maxillary sinusitis or rhinosinusitis in France and literature review. ( 16405280 )
2005
30
Recovery of interfering bacteria in the nasopharynx following antimicrobial therapy of acute maxillary sinusitis with telithromycin or amoxicillin-clavulanate. ( 16251334 )
2005
31
Eradication of pathogens from the nasopharynx after therapy of acute maxillary sinusitis with low- or high-dose amoxicillin/clavulanic acid. ( 16226017 )
2005
32
Clinical and bacteriological efficacy of 5-day telithromycin in acute maxillary sinusitis: a pooled analysis. ( 15780415 )
2005
33
Use of pharmacodynamic end points in the evaluation of gatifloxacin for the treatment of acute maxillary sinusitis. ( 15156435 )
2004
34
Antimicrobial resistance in the nasopharyngeal flora of children with acute maxillary sinusitis and maxillary sinusitis recurring after amoxicillin therapy. ( 14729759 )
2004
35
Management of acute maxillary sinusitis in Finnish primary care. Results from the nationwide MIKSTRA study. ( 15255494 )
2004
36
Patients' and physicians' views on the management of acute maxillary sinusitis. ( 15119516 )
2004
37
Antibiotics for acute maxillary sinusitis. ( 12804392 )
2003
38
Efficacy and tolerability of telithromycin for 5 or 10 days vs amoxicillin/clavulanic acid for 10 days in acute maxillary sinusitis. ( 14503094 )
2003
39
Evidence-based emergency medicine/systematic review abstract: Antibiotic treatment for acute maxillary sinusitis. ( 14581925 )
2003
40
Clinical inquiries. Are antibiotics helpful for acute maxillary sinusitis? ( 12791232 )
2003
41
The treatment duration of acute maxillary sinusitis: how long should it be? A nasal smear controlled study. ( 12526248 )
2002
42
Diagnostic accuracy of acute maxillary sinusitis in adults in primary care. ( 12086283 )
2002
43
Efficacy and tolerability of once-daily therapy with telithromycin for 5 or 10 days for the treatment of acute maxillary sinusitis. ( 12011543 )
2002
44
Moxifloxacin versus amoxicillin clavulanate in the treatment of acute maxillary sinusitis: a primary care experience. ( 11452678 )
2001
45
Phase III, randomized, double-blind study of clarithromycin extended-release and immediate-release formulations in the treatment of adult patients with acute maxillary sinusitis. ( 11192134 )
2000
46
Which antibiotics lead to higher clinical cure rates in adults with acute maxillary sinusitis? ( 10903293 )
2000
47
Comparison of ultrasound, radiography, and clinical examination in the diagnosis of acute maxillary sinusitis: a systematic review. ( 11004420 )
2000
48
Antibiotics for acute maxillary sinusitis. ( 10796515 )
2000
49
Validity of ultrasonography in diagnosis of acute maxillary sinusitis. ( 11115287 )
2000
50
Comparison of moxifloxacin and cefuroxime axetil in the treatment of acute maxillary sinusitis. Sinusitis Infection Study Group. ( 10566563 )
1999

Variations for Acute Maxillary Sinusitis

Expression for Acute Maxillary Sinusitis

Search GEO for disease gene expression data for Acute Maxillary Sinusitis.

Pathways for Acute Maxillary Sinusitis

Pathways related to Acute Maxillary Sinusitis according to GeneCards Suite gene sharing:

# Super pathways Score Top Affiliating Genes
1 10.52 CD40LG CD79A
2 9.8 F9 GAS6

GO Terms for Acute Maxillary Sinusitis

Cellular components related to Acute Maxillary Sinusitis according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 endoplasmic reticulum lumen GO:0005788 8.8 C3 F9 GAS6

Biological processes related to Acute Maxillary Sinusitis according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 positive regulation of phagocytosis GO:0050766 9.16 C3 GAS6
2 B cell proliferation GO:0042100 8.96 CD40LG CD79A
3 signal peptide processing GO:0006465 8.62 F9 GAS6

Sources for Acute Maxillary Sinusitis

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
17 ExPASy
19 FMA
28 GO
29 GTR
30 HGMD
31 HMDB
32 HPO
33 ICD10
34 ICD10 via Orphanet
35 ICD9CM
36 IUPHAR
37 KEGG
38 LifeMap
40 LOVD
42 MedGen
44 MeSH
45 MESH via Orphanet
46 MGI
49 NCI
50 NCIt
51 NDF-RT
54 NINDS
55 Novoseek
57 OMIM
58 OMIM via Orphanet
62 PubMed
64 QIAGEN
69 SNOMED-CT via HPO
70 SNOMED-CT via Orphanet
71 TGDB
72 Tocris
73 UMLS
74 UMLS via Orphanet
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