AMAN
MCID: ACT181
MIFTS: 26

Acute Motor Axonal Neuropathy (AMAN)

Categories: Neuronal diseases, Rare diseases

Aliases & Classifications for Acute Motor Axonal Neuropathy

MalaCards integrated aliases for Acute Motor Axonal Neuropathy:

Name: Acute Motor Axonal Neuropathy 58 71
Acute Pure Motor Guillain-Barre Syndrome 58
Acute Pure Motor Gbs 58
Aman 58

Characteristics:

Orphanet epidemiological data:

58
acute motor axonal neuropathy
Inheritance: Multigenic/multifactorial,Not applicable; Age of onset: All ages; Age of death: any age;

Classifications:

Orphanet: 58  
Rare neurological diseases


External Ids:

ICD10 via Orphanet 33 G61.0
Orphanet 58 ORPHA98918
UMLS 71 C3890941

Summaries for Acute Motor Axonal Neuropathy

MalaCards based summary : Acute Motor Axonal Neuropathy, also known as acute pure motor guillain-barre syndrome, is related to guillain-barre syndrome and neuropathy. The drugs Risperidone and Dopamine have been mentioned in the context of this disorder. Affiliated tissues include t cells, bone and brain.

Wikipedia : 74 Acute motor axonal neuropathy (AMAN) is a variant of Guillain-Barré syndrome. It is characterized by... more...

Related Diseases for Acute Motor Axonal Neuropathy

Diseases related to Acute Motor Axonal Neuropathy via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50) (show all 67)
# Related Disease Score Top Affiliating Genes
1 guillain-barre syndrome 11.8
2 neuropathy 11.0
3 axonal neuropathy 11.0
4 polyneuropathy 10.6
5 demyelinating polyneuropathy 10.5
6 quadriplegia 10.4
7 myelitis 10.4
8 miller fisher syndrome 10.3
9 polyradiculoneuropathy 10.3
10 transverse myelitis 10.3
11 acute motor and sensory axonal neuropathy 10.2
12 kearns-sayre syndrome 10.2
13 respiratory failure 10.2
14 hepatitis a 10.2
15 cholera 10.2
16 hepatitis e 10.2
17 poliomyelitis 10.2
18 peripheral nervous system disease 10.2
19 influenza 10.2
20 macrophage activation syndrome 10.2
21 multinucleated neurons, anhydramnios, renal dysplasia, cerebellar hypoplasia, and hydranencephaly 10.1
22 myasthenia gravis 10.1
23 graft-versus-host disease 10.1
24 acute diarrhea 10.1
25 hypoparathyroidism 10.1
26 acute leukemia 10.1
27 acute cystitis 10.1
28 congenital toxoplasmosis 10.1
29 substance abuse 10.1
30 postpartum depression 10.1
31 toxoplasmosis 10.1
32 foot drop 10.1
33 amyotrophic lateral sclerosis 1 10.0
34 autoimmune disease 10.0
35 multiple sclerosis 10.0
36 systemic lupus erythematosus 10.0
37 celiac disease 1 10.0
38 enterocolitis 10.0
39 ataxia and polyneuropathy, adult-onset 10.0
40 meningococcal meningitis 10.0
41 xerophthalmia 10.0
42 endocarditis 10.0
43 aseptic meningitis 10.0
44 keratoconjunctivitis sicca 10.0
45 diarrhea 10.0
46 toxic shock syndrome 10.0
47 neuroleptic malignant syndrome 10.0
48 alcohol use disorder 10.0
49 impotence 10.0
50 cerebral palsy 10.0

Graphical network of the top 20 diseases related to Acute Motor Axonal Neuropathy:



Diseases related to Acute Motor Axonal Neuropathy

Symptoms & Phenotypes for Acute Motor Axonal Neuropathy

Drugs & Therapeutics for Acute Motor Axonal Neuropathy

Drugs for Acute Motor Axonal Neuropathy (from DrugBank, HMDB, Dgidb, PharmGKB, IUPHAR, NovoSeek, BitterDB):

(show all 11)
# Name Status Phase Clinical Trials Cas Number PubChem Id
1
Risperidone Approved, Investigational Phase 3 106266-06-2 5073
2
Dopamine Approved Phase 3 51-61-6, 62-31-7 681
3 Dopamine Agents Phase 3
4 Dopamine Antagonists Phase 3
5 Psychotropic Drugs Phase 3
6 Antipsychotic Agents Phase 3
7 Neurotransmitter Agents Phase 3
8 Interleukin-23 Phase 3
9
Serotonin Investigational, Nutraceutical Phase 3 50-67-9 5202
10 Omega 3 Fatty Acid Phase 1
11
Amantadine Approved 768-94-5 2130

Interventional clinical trials:


# Name Status NCT ID Phase Drugs
1 Effects of Risperidone on Cognitive-Motor Performance and Motor Movements in Chronically Medicated Children Completed NCT00399698 Phase 3 Risperdal
2 A Phase 3, Multicenter, Randomized, Double-Blind, Parallel-Arm, Placebo-Controlled Maintenance Study of Mirikizumab in Patients With Moderately to Severely Active Ulcerative Colitis (LUCENT 2) Recruiting NCT03524092 Phase 3 Mirikizumab;Mirikizumab;Placebo
3 Omega-3 Fatty Acids & Psychoeducational Psychotherapy for Childhood Depression Completed NCT01341925 Phase 1 Omega-3 Supplementation
4 Adaptation and Validation of a Community Worker Administered Stroke Symptom Questionnaire in a Peri-urban Pakistani Community Completed NCT02073955
5 Comparison of DSM-IV-TR and DSM-5 Diagnostic Criteria for Autism Spectrum Disorder Completed NCT02296502
6 Early Prediction of Respiratory and Autonomic Complications of GBS Using Neuromuscular Ultrasound Recruiting NCT04166357
7 Spatial Analysis Optimization of Prehospital Services in Karachi, Pakistan to Improve Ambulance Response Times Active, not recruiting NCT02743169
8 Reperfusion of Pulmonary Arteriovenous Malformations After Embolotherapy. A Randomized Trial of Interlock™ Fibered IDC™ Occlusion System vs. Nester Coils Active, not recruiting NCT01856842

Search NIH Clinical Center for Acute Motor Axonal Neuropathy

Genetic Tests for Acute Motor Axonal Neuropathy

Anatomical Context for Acute Motor Axonal Neuropathy

MalaCards organs/tissues related to Acute Motor Axonal Neuropathy:

40
T Cells, Bone, Brain, Bone Marrow, Eye, Spinal Cord, Breast

Publications for Acute Motor Axonal Neuropathy

Articles related to Acute Motor Axonal Neuropathy:

(show top 50) (show all 514)
# Title Authors PMID Year
1
Graft-versus-host disease-related neuropathy: AMAN phenotype with improvement after plasmapheresis. 61
31552556 2020
2
Perisynaptic Schwann cells phagocytose nerve terminal debris in a mouse model of Guillain-Barré syndrome. 61
32250537 2020
3
Clinical Characteristics and Electrodiagnostic Features of Guillain-Barré Syndrome Among the Pediatric Population. 61
32156188 2020
4
Distinct anti-dyskinetic effects of amantadine and group II metabotropic glutamate receptor agonist LY354740 in a rodent model: An electrophysiological perspective. 61
32088382 2020
5
Clinical features of Guillain-Barré syndrome patients with elevated serum creatine kinase levels. 61
32460711 2020
6
Comparison of the Clinical Outcomes of Guillain Barre Syndrome Based on Electrophysiological Subtypes in Pakistani Children. 61
32537271 2020
7
[Variant AMAN of the Guillain-Barré syndrome in an octogenarian patient]. 61
31272805 2020
8
Axonal variants of Guillain-Barré syndrome: an update. 61
32140865 2020
9
Hyper-reflexia in Guillain-Barré syndrome: systematic review. 61
31937584 2020
10
Effect of Maternal Exposure to Seasons during the Second and Third Trimesters of Pregnancy on Infant Birth Weight in Rural Bangladesh. 61
32154502 2020
11
Transcriptional Sequencing and Gene Expression Analysis of Various Genes in Fruit Development of Three Different Black Pepper (Piper nigrum L.) Varieties. 61
32399475 2020
12
Fatal Acute Motor Axonal Neuropathy Induced by Nivolumab: A Case Report and Literature Review. 61
31471269 2019
13
Prognostic factors for the sequelae and severity of Guillain-Barré syndrome in children. 61
31531862 2019
14
Serum CXCL13 reflects local B-cell mediated inflammatory demyelinating peripheral neuropathy. 61
31712675 2019
15
Rapid Recovery With Plasma Exchange in Acute Motor Axonal Neuropathy With Reversible Conduction Failure. 61
31453853 2019
16
Agronomic, economic, and environmental performance of nitrogen rates and source in Bangladesh's coastal rice agroecosystems. 61
31534298 2019
17
[Guillain-Barre syndrome complicated on post-operation with renal carcinoma and meningioma: a case report]. 61
31420639 2019
18
A Rare Case of Acute Transverse Myelitis (ATM) and Acute Motor and Sensory Axonal Neuropathy (AMSAN) Overlap. 61
31632877 2019
19
Role of IV Immunoglobulin in Indian Children With Guillain-Barré Syndrome. 61
30985608 2019
20
Acute motor axonal neuropathy form of the Guillain Barre syndrome two months after bariatric surgery. 61
31133339 2019
21
Guillain-Barre syndrome in North Indian children: Clinical and serial electrophysiological features. 61
31347543 2019
22
Role of Anti-ganglioside Antibodies in the Diagnosis of Guillain-Barré Syndrome as an Alternate Investigation. 61
31312551 2019
23
Guillain Barre syndrome with pulmonary tuberculosis: A case series from a tertiary care hospital. 61
31198762 2019
24
[Classification of pregnancy complicating Guillain-Barré syndrome]. 61
31137128 2019
25
Toll-like receptor-4 299Gly allele is associated with Guillain-Barré syndrome in Bangladesh. 61
31019995 2019
26
A 30-Year-Old Man with Acute Motor Axonal Neuropathy Subtype of Guillain-Barré Syndrome Having Hepatitis A Virus Infection. 61
31380008 2019
27
How Different is AMAN from AIDP in Childhood GBS? A Prospective Study from North India. 61
30637680 2019
28
Synthesis of 1-(α-aminoalkyl)-2-naphthol and α-aminonitrile derivatives with molybdenum Schiff base complex covalently bonded on silica-coated magnetic nanoparticles and DNA interaction study of one type of derivatives using computational and spectroscopic methods. 61
30665036 2019
29
High resolution paddy rice maps in cloud-prone Bangladesh and Northeast India using Sentinel-1 data. 61
30976017 2019
30
How Important it is to Differentiate AMAN from AIDP in Childhood GBS? A Clinician's Perspective. 61
30847866 2019
31
Atypical Clinical Presentations of Pediatric Acute Immune-Mediated Polyneuropathy. 61
30674221 2019
32
Fatal, paraparetic acute motor axonal neuropathy, early complicating chemotherapy with nab-paclitaxel. 61
30589645 2019
33
Autoimmunity and cytokines in Guillain-Barré syndrome revisited: review of pathomechanisms with an eye on therapeutic options. 61
31074417 2019
34
Increased incidence of axonal Guillain-Barré syndrome in La Spezia area of Italy: A 13-year follow-up study. 61
30421471 2019
35
Clinical, electrophysiological findings and evaluation of prognosis of patients with Guillain-Barré syndrome. 61
32077646 2019
36
Integrative metabolomics reveals unique metabolic traits in Guillain-Barré Syndrome and its variants. 61
30705347 2019
37
Guillain-Barré Syndrome. 61
31760653 2019
38
The Mitochondrial tRNAHis G12192A Mutation May Modulate the Clinical Expression of Deafness-Associated tRNAThr G15927A Mutation in a Chinese Pedigree. 61
30854964 2019
39
An overlapping case of Bickerstaff brainstem encephalitis and acute motor axonal neuropathy variant of Guillain-Barré syndrome associated with systemic lupus erythematosus. 61
30444497 2019
40
Electrophysiological Subtypes and Prognostic Factors of Guillain-Barre Syndrome in Northern China. 61
31333568 2019
41
Clinical Profile, Functional Outcome, and Mortality of Guillain-Barre Syndrome: A Five-Year Tertiary Care Experience from Nepal. 61
31275647 2019
42
Over the Counter Sale of Antibiotics at Drug Stores Found in Mizan-Aman Town, Southwest Ethiopia: A Cross-Sectional Simulated Client Visit Study. 61
31080686 2019
43
Metabolic syndrome among residents of Mizan-Aman town, South West Ethiopia, 2017: A cross sectional study. 61
30703130 2019
44
Psychometric properties of the perceived stress scale in Ethiopian university students. 61
30626438 2019
45
Magnitude of postpartum depression and associated factors among women in Mizan Aman town, Bench Maji zone, Southwest Ethiopia. 61
30428843 2018
46
Incidence and outcome of Guillain-Barré syndrome in Iceland: A population-based study. 61
30019469 2018
47
Human parechovirus type 6 and Guillain-Barré syndrome: a case report. 61
29995288 2018
48
Bilateral spinal anterior horn lesions in acute motor axonal neuropathy. 61
29853225 2018
49
Poor sleep in concurrent users of alcohol, khat, and tobacco smoking in community-dwelling Ethiopian adults. 61
30416593 2018
50
[The most frequent causative agents of Guillain-Barre syndrome in a Mexican general hospital]. 61
30183060 2018

Variations for Acute Motor Axonal Neuropathy

Expression for Acute Motor Axonal Neuropathy

Search GEO for disease gene expression data for Acute Motor Axonal Neuropathy.

Pathways for Acute Motor Axonal Neuropathy

GO Terms for Acute Motor Axonal Neuropathy

Sources for Acute Motor Axonal Neuropathy

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
17 EFO
18 ExPASy
19 FMA
28 GO
29 GTR
30 HMDB
31 HPO
32 ICD10
33 ICD10 via Orphanet
34 ICD9CM
35 IUPHAR
36 KEGG
37 LifeMap
39 LOVD
41 MedGen
43 MeSH
44 MESH via Orphanet
45 MGI
48 NCI
49 NCIt
50 NDF-RT
53 NINDS
54 Novoseek
56 OMIM
57 OMIM via Orphanet
61 PubMed
63 QIAGEN
68 SNOMED-CT via HPO
69 TGDB
70 Tocris
71 UMLS
72 UMLS via Orphanet
Content
Loading form....