MCID: ACT190
MIFTS: 17

Acute Myeloid Leukemia with T(8;16)(p11;p13) Translocation

Categories: Blood diseases, Cancer diseases, Rare diseases

Aliases & Classifications for Acute Myeloid Leukemia with T(8;16)(p11;p13) Translocation

MalaCards integrated aliases for Acute Myeloid Leukemia with T(8;16)(p11;p13) Translocation:

Name: Acute Myeloid Leukemia with T(8;16)(p11;p13) Translocation 60
Aml with T(8;16)(p11;p13) Translocation 60

Classifications:



External Ids:

ICD10 via Orphanet 35 C92.0
Orphanet 60 ORPHA370026

Summaries for Acute Myeloid Leukemia with T(8;16)(p11;p13) Translocation

MalaCards based summary : Acute Myeloid Leukemia with T(8;16)(p11;p13) Translocation, also known as aml with t(8;16)(p11;p13) translocation, is related to leukemia, acute myeloid and leukemia. An important gene associated with Acute Myeloid Leukemia with T(8;16)(p11;p13) Translocation is KAT6A (Lysine Acetyltransferase 6A), and among its related pathways/superpathways are fMLP Pathway and Chromatin organization. Affiliated tissues include myeloid.

Related Diseases for Acute Myeloid Leukemia with T(8;16)(p11;p13) Translocation

Diseases in the Acute Myeloid Leukemia with T(8;16)(p11;p13) Translocation family:

Acute Myeloid Leukemia with T(8;21)(q22;q22) Translocation

Diseases related to Acute Myeloid Leukemia with T(8;16)(p11;p13) Translocation via text searches within MalaCards or GeneCards Suite gene sharing:

# Related Disease Score Top Affiliating Genes
1 leukemia, acute myeloid 10.5
2 leukemia 10.5
3 myeloid leukemia 10.5
4 chromosome 16p13.3 deletion syndrome, proximal 9.7 CREBBP KAT6A
5 neonatal leukemia 9.6 CREBBP KAT6A
6 leukemia, acute monocytic 9.5 CREBBP KAT6A

Graphical network of the top 20 diseases related to Acute Myeloid Leukemia with T(8;16)(p11;p13) Translocation:



Diseases related to Acute Myeloid Leukemia with T(8;16)(p11;p13) Translocation

Symptoms & Phenotypes for Acute Myeloid Leukemia with T(8;16)(p11;p13) Translocation

Drugs & Therapeutics for Acute Myeloid Leukemia with T(8;16)(p11;p13) Translocation

Search Clinical Trials , NIH Clinical Center for Acute Myeloid Leukemia with T(8;16)(p11;p13) Translocation

Genetic Tests for Acute Myeloid Leukemia with T(8;16)(p11;p13) Translocation

Anatomical Context for Acute Myeloid Leukemia with T(8;16)(p11;p13) Translocation

MalaCards organs/tissues related to Acute Myeloid Leukemia with T(8;16)(p11;p13) Translocation:

42
Myeloid

Publications for Acute Myeloid Leukemia with T(8;16)(p11;p13) Translocation

Articles related to Acute Myeloid Leukemia with T(8;16)(p11;p13) Translocation:

# Title Authors Year
1
Type I MOZ/CBP (MYST3/CREBBP) is the most common chimeric transcript in acute myeloid leukemia with t(8;16)(p11;p13) translocation. ( 15101047 )
2004

Variations for Acute Myeloid Leukemia with T(8;16)(p11;p13) Translocation

Expression for Acute Myeloid Leukemia with T(8;16)(p11;p13) Translocation

Search GEO for disease gene expression data for Acute Myeloid Leukemia with T(8;16)(p11;p13) Translocation.

Pathways for Acute Myeloid Leukemia with T(8;16)(p11;p13) Translocation

GO Terms for Acute Myeloid Leukemia with T(8;16)(p11;p13) Translocation

Cellular components related to Acute Myeloid Leukemia with T(8;16)(p11;p13) Translocation according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 nuclear chromatin GO:0000790 8.96 CREBBP KAT6A
2 histone acetyltransferase complex GO:0000123 8.62 CREBBP KAT6A

Biological processes related to Acute Myeloid Leukemia with T(8;16)(p11;p13) Translocation according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 positive regulation of transcription, DNA-templated GO:0045893 9.16 CREBBP KAT6A
2 histone acetylation GO:0016573 8.96 CREBBP KAT6A
3 protein acetylation GO:0006473 8.62 CREBBP KAT6A

Molecular functions related to Acute Myeloid Leukemia with T(8;16)(p11;p13) Translocation according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 zinc ion binding GO:0008270 9.37 CREBBP KAT6A
2 transcription factor binding GO:0008134 9.32 CREBBP KAT6A
3 transcription coactivator activity GO:0003713 9.26 CREBBP KAT6A
4 transferase activity, transferring acyl groups GO:0016746 9.16 CREBBP KAT6A
5 histone acetyltransferase activity GO:0004402 8.96 CREBBP KAT6A
6 acetyltransferase activity GO:0016407 8.62 CREBBP KAT6A

Sources for Acute Myeloid Leukemia with T(8;16)(p11;p13) Translocation

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
17 EFO
18 ExPASy
20 FMA
29 GO
30 GTR
31 HGMD
32 HMDB
33 HPO
34 ICD10
35 ICD10 via Orphanet
36 ICD9CM
37 IUPHAR
38 KEGG
39 LifeMap
41 LOVD
43 MedGen
45 MeSH
46 MESH via Orphanet
47 MGI
50 NCI
51 NCIt
52 NDF-RT
55 NINDS
56 Novoseek
58 OMIM
59 OMIM via Orphanet
63 PubMed
65 QIAGEN
70 SNOMED-CT via HPO
71 SNOMED-CT via Orphanet
72 TGDB
73 Tocris
74 UMLS
75 UMLS via Orphanet
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