Acute Myocardial Infarction disease: Malacards - Research Articles, Drugs, Genes, Clinical Trials

MCID: ACT075 MIFTS: 59	Acute Myocardial Infarction Categories: Cardiovascular diseases, Genetic diseases	Data Licensing For inquiries, contact: [email protected]
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Aliases & Classifications for Acute Myocardial Infarction

MalaCards integrated aliases for Acute Myocardial Infarction:

Name: Acute Myocardial Infarction ¹¹ ⁵³ ⁵ ¹⁴ ¹⁶ ⁷¹ ³¹ ³³

Cardiac Attack ³³

Heart Attack ³³

Classifications:

MalaCards categories:
Global: Genetic diseases
Anatomical: Cardiovascular diseases

See all MalaCards categories (disease lists)

ICD10: ³¹

Diseases of the circulatory system

Ischaemic heart diseases

Acute myocardial infarction

Acute myocardial infarction, unspecified

ICD11: ³³

Diseases of the circulatory system

Ischaemic heart diseases

Acute ischaemic heart disease

Acute myocardial infarction

Acute myocardial infarction, unspecified

External Ids:

Disease Ontology ¹¹ DOID:9408

ICD9CM ³⁴ 410

NCIt ⁴⁹ C35204

SNOMED-CT ⁶⁸ 155304006

ICD10 ³¹ I21 I21.9

EFO ¹⁶ EFO_0008583

ICD11 ³³ 1334938734 1334938734/unspecified

UMLS ⁷¹ C0155626

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Summaries for Acute Myocardial Infarction

MalaCards based summary: Acute Myocardial Infarction, also known as cardiac attack, is related to cardiogenic shock and angina pectoris, and has symptoms including angina pectoris and chest pain. An important gene associated with Acute Myocardial Infarction is MIR208B (MicroRNA 208b), and among its related pathways/superpathways is Mesenchymal Stem Cells and Lineage-specific Markers. The drugs Colchicine and Dabigatran have been mentioned in the context of this disorder. Affiliated tissues include heart, bone marrow and bone, and related phenotypes are muscle and cardiovascular system

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Related Diseases for Acute Myocardial Infarction

Diseases in the Myocardial Infarction family:

Myocardial Infarction 2	Posterior Myocardial Infarction
Acute Myocardial Infarction

Diseases related to Acute Myocardial Infarction via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50) (show all 1217)

#	Related Disease	Score	Top Affiliating Genes
1	cardiogenic shock	33.1	PLAT PIK3C2A NPPB
2	angina pectoris	32.9	TNNI3 PLAT PIK3C2A NPPB MB F3
3	acute anterolateral myocardial infarction	32.8	PIK3C2A NPPB CRP ACE
4	intermediate coronary syndrome	32.7	TNNT2 TNNI3 NPPB MIR499A MB F3
5	myocardial infarction	32.5	TNNT2 TNNI3 PLAT PIK3C2A NPPB MIR499A
6	cardiac arrest	32.4	TNNT2 TNNI3 NPPB MIR499A MB FABP3
7	congestive heart failure	32.4	TNNT2 TNNI3 NPPB FABP3 CDKN2B-AS1 ACE
8	atrioventricular block	32.4	TNNT2 TNNI3 PIK3C2A NPPB CRP ACE
9	left bundle branch hemiblock	32.4	TNNT2 TNNI3 NPPB CRP ACE
10	third-degree atrioventricular block	32.3	TNNI3 NPPB CRP ACE
11	mitral valve insufficiency	32.3	TNNT2 TNNI3 NPPB F3 CRP ACE
12	coronary stenosis	32.3	TNNI3 PIK3C2A NPPB CRP ACE
13	coronary thrombosis	32.3	TNNI3 PLAT MIR499A F3 CRP
14	atrial fibrillation	32.3	TNNI3 PLAT NPPB F3 CRP ACE
15	inferior myocardial infarction	32.3	TNNT2 TNNI3 PLAT PIK3C2A NPPB ACE
16	pulmonary edema	32.2	TNNT2 TNNI3 PIK3C2A NPPB CRP ACE
17	pericarditis	32.2	TNNT2 TNNI3 NPPB CRP ACE
18	heart septal defect	32.2	TNNT2 NPPB MIR499A F3 CRP
19	coronary artery vasospasm	32.2	TNNT2 TNNI3 PIK3C2A NPPB MB F3
20	myocarditis	32.2	TNNT2 TNNI3 PIK3C2A NPPB MB F3
21	hypokalemia	32.2	PIK3C2A MB ACE
22	chronic kidney disease	32.1	TNNT2 TNNI3 NPPB CRP ACE
23	peripheral vascular disease	32.1	PLAT F3 CRP ACE
24	right bundle branch block	32.1	TNNT2 TNNI3 NPPB CRP ACE
25	stroke, ischemic	32.0	PLAT NPPB MB F3 CRP CDKN2B-AS1
26	aortic dissection	32.0	TNNT2 CRP ACE
27	pericardial effusion	32.0	TNNT2 TNNI3 PIK3C2A NPPB MB F3
28	ventricular septal defect	32.0	TNNT2 NPPB MIR499A
29	cardiac tamponade	32.0	TNNI3 PLAT PIK3C2A NPPB F3 CRP
30	ischemia	32.0	TNNT2 PLAT PIK3C2A NPPB MB FABP3
31	respiratory failure	31.9	TNNI3 PIK3C2A NPPB MB F3 CRP
32	pulmonary embolism	31.9	TNNT2 TNNI3 PLAT NPPB MB FABP3
33	pulmonary disease, chronic obstructive	31.9	NPPB MB CRP ACE
34	acute kidney failure	31.9	PIK3C2A MB ACE
35	antiphospholipid syndrome	31.9	PLAT F3 CRP
36	sleep apnea	31.8	NPPB CRP ACE
37	transient cerebral ischemia	31.8	PLAT NPPB F3 CRP ACE
38	anteroseptal myocardial infarction	31.8	PIK3C2A MB ACE
39	endocarditis	31.8	TNNT2 TNNI3 PLAT PIK3C2A CRP
40	anterolateral myocardial infarction	31.8	PLAT NPPB ACE
41	hemopericardium	31.8	TNNI3 PLAT NPPB F3 CRP
42	acute myocarditis	31.8	TNNT2 TNNI3 NPPB MIR499A CRP ACE
43	apnea, obstructive sleep	31.7	NPPB CRP ACE
44	coronary aneurysm	31.7	NPPB F3 CRP ACE
45	infective endocarditis	31.7	NPPB F3 CRP ACE
46	heart disease	31.7	TNNT2 TNNI3 PLAT PIK3C2A NPPB MIR499A
47	myocardial stunning	31.7	TNNT2 TNNI3 NPPB ACE
48	hypothyroidism	31.7	PIK3C2A NPPB F3 CRP ACE
49	lipoprotein quantitative trait locus	31.7	TNNT2 TNNI3 PLAT PIK3C2A NPPB MIR499A
50	atherosclerosis susceptibility	31.7	PLAT F3 CRP CDKN2B-AS1 ACE

Comorbidity relations with Acute Myocardial Infarction via Phenotypic Disease Network (PDN): (show all 20)

Graphical network of the top 20 diseases related to Acute Myocardial Infarction:

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Symptoms & Phenotypes for Acute Myocardial Infarction

UMLS symptoms related to Acute Myocardial Infarction:

angina pectoris; chest pain

MGI Mouse Phenotypes related to Acute Myocardial Infarction:

⁴⁵

#	Description	MGI Source Accession	Score	Top Affiliating Genes
1	muscle	MP:0005369	9.61	F3 FABP3 MB MIR208B MIR499A NPPB
2	cardiovascular system	MP:0005385	9.36	ACE CRP F3 FABP3 IDH2 MB

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Drugs & Therapeutics for Acute Myocardial Infarction

Drugs for Acute Myocardial Infarction (from DrugBank, HMDB, Dgidb, PharmGKB, IUPHAR, NovoSeek, BitterDB):

(show top 50) (show all 346)

Name

Status

Phase

Clinical Trials

Cas Number

PubChem Id

Colchicine

Approved

Phase 4

64-86-8

2833 6167

Dabigatran

Approved, Investigational

Phase 4

211914-51-1

216210

Streptokinase

Approved, Investigational

Phase 4

9002-01-1

Insulin glargine

Approved

Phase 4

160337-95-1

118984454

Benzocaine

Approved, Investigational

Phase 4

1994-09-7, 94-09-7

2337

Tannic acid

Approved

Phase 4

1401-55-4

16129878 16129778

Abciximab

Approved

Phase 4

143653-53-6

3815015

Lenograstim

Approved, Investigational

Phase 4

135968-09-1

Nitroglycerin

Approved, Investigational

Phase 4

55-63-0

4510

Bezafibrate

Approved, Investigational

Phase 4

41859-67-0

39042

Metoclopramide

Approved, Investigational

Phase 4

364-62-5

4168

Verapamil

Approved

Phase 4

152-11-4, 52-53-9

2520

Tirofiban

Approved

Phase 4

144494-65-5

60947

Reteplase

Approved, Investigational

Phase 4

133652-38-7

Diltiazem

Approved, Investigational

Phase 4

42399-41-7

39186

Irbesartan

Approved, Investigational

Phase 4

138402-11-6

3749

Reviparin

Approved, Investigational

Phase 4

9041-08-1

Eplerenone

Approved

Phase 4

107724-20-9

443872

Cilostazol

Approved, Investigational

Phase 4

73963-72-1

2754

Insulin lispro

Approved

Phase 4

133107-64-9

16132438

Zinc cation

Approved, Experimental, Investigational

Phase 4

7440-66-6, 23713-49-7

32051

Apricot

Approved

Phase 4

Aminophylline

Approved

Phase 4

317-34-0

9433

Edaravone

Approved, Investigational

Phase 4

89-25-8

4021 70335

Acetylcysteine

Approved, Investigational

Phase 4

616-91-1

581 12035

Esomeprazole

Approved, Investigational, Vet_approved

Phase 4

73590-58-6, 119141-88-7

9568614 4594

Famotidine

Approved

Phase 4

76824-35-6

3325 5702160

Histamine

Approved, Investigational

Phase 4

51-45-6

774

Metoprolol

Approved, Investigational

Phase 4

37350-58-6, 51384-51-1

4171

Evolocumab

Approved

Phase 4

1256937-27-5

Dopamine

Approved

Phase 4

62-31-7, 51-61-6

681

Cangrelor

Approved

Phase 4

163706-06-7

9854012

Pitavastatin

Approved

Phase 4

147511-69-1

5282452

Atenolol

Approved

Phase 4

29122-68-7

2249

Ezetimibe

Approved

Phase 4

163222-33-1

150311

Carvedilol

Approved, Investigational

Phase 4

72956-09-3

2585

Bisoprolol

Approved

Phase 4

66722-44-9

2405

Warfarin

Approved

Phase 4

81-81-2, 129-06-6

54678486

Rivaroxaban

Approved

Phase 4

366789-02-8

9875401

Nebivolol

Approved, Investigational

Phase 4

152520-56-4, 99200-09-6, 118457-14-0

71301

Everolimus

Approved

Phase 4

159351-69-6

70789204 6442177

Cobalt

Approved, Experimental, Withdrawn

Phase 4

7440-48-4

104729

Chromium

Approved

Phase 4

7440-47-3

27668

Acetylsalicylic acid

Approved, Vet_approved

Phase 4

50-78-2

2244

Norepinephrine

Approved

Phase 4

51-41-2

439260

Dapagliflozin

Approved

Phase 4

461432-26-8

9887712

Nicorandil

Approved, Investigational

Phase 4

65141-46-0

47528

Ticagrelor

Approved

Phase 4

274693-27-5

9871419

Heparin, bovine

Approved, Investigational, Withdrawn

Phase 4

9005-49-6

22833565 9812414 772

Tenecteplase

Approved

Phase 4

191588-94-0

Interventional clinical trials:

(show top 50) (show all 862)

#	Name	Status	NCT ID	Phase	Drugs
1	Pravastatin for Acute Myocardial Infarction With Minimally to Mildly Increased Levels of Serum Cholesterol Study That Evaluates the Effects of Pravastatin for Acute Myocardial Infarction With LDL-Cholesterol Levels of 70-129 mg/dl	Unknown status	NCT00688922	Phase 4	Pravastatin
2	Role of Innate and Adaptive Immunity After Acute Myocardial Infarction BATTLE-AMI Study (B And T Types of Lymphocytes Evaluation in Acute Myocardial Infarction)	Unknown status	NCT02428374	Phase 4	Rosuvastatin plus clopidogrel;Rosuvastatin plus ticagrelor;Simvastatin plus clopidogrel;Simvastatin plus ticagrelor
3	A Randomized Clinical Trial Comparing Primary PCI and Post-thrombolysis PCI as Reperfusion Strategies in Patients With ST Segment Elevation Acute Myocardial Infarction	Unknown status	NCT02268669	Phase 4
4	Erythropoietin Prevention Trial of Coronary Restenosis and Cardiac Remodeling After Acute Myocardial Infarction (EPOC-AMI)	Unknown status	NCT00423020	Phase 4	Erythropoietin
5	China Tongxinluo Study for Myocardial Protection in Patients With Acute Myocardial Infarction	Unknown status	NCT03792035	Phase 4	Tongxinluo;Placebos
6	Adjunctive Cilostazol to Dual Antiplatelet Therapy to Enhance Mobilization of Endothelial Progenitor Cell in Patients With Acute Myocardial Infarction: A Randomized, Placebo-controlled ACCEL-EPISODE Trial	Unknown status	NCT04407312	Phase 4	Cilostazol Tablets;placebo;Aspirin;Clopidogrel
7	Multicentre 2x2 Factorial Randomised Study Comparing Tirofiban Administered With the Single High-Dose Bolus Versus Abciximab and Sirolimus Eluting Stent Versus Bare Metal Stent in Acute Myocardial Infarction - MULTI-STRATEGY Trial	Unknown status	NCT00229515	Phase 4
8	Randomized Study Of Sirolimus Eluting Stent Vs Conventional Stent In Acute Myocardial Infarction Acronym SESAMI	Unknown status	NCT00288210	Phase 4
9	A Multi-center Study on the Optimized Antithrombotic Therapy of Acute Myocardial Infarction With Left Ventricular Mural Thrombus.	Unknown status	NCT03415386	Phase 4	Combination of antiplatelet drugs and anticoagulants for at least one month
10	Thyroid Hormone Replacement for Hypothyroidism and Acute Myocardial Infarction	Unknown status	NCT02512978	Phase 4	Levothyroxine
11	Randomized, Prospective , Open Label, Phase 4 Trial of Efficacy and Safety of Adjunctive Cilostazol in Acute Myocardial Infarction Patients Undergoing Percutaneous Coronary Intervention With Drug-eluting Stent	Unknown status	NCT01261832	Phase 4	antiplatelet therapy
12	Microvascular Reperfusion Utilizing Sonothrombolysis in Acute Myocardial Infarction (MRUSMI TRIAL)	Unknown status	NCT02170103	Phase 4	Microbubbles
13	Efficacy of Thrombosuction in Primary Percutaneous Coronary Intervention of Acute Myocardial Infarction	Unknown status	NCT01156662	Phase 4
14	Dissecting the Role of Distal Embolization of Athero-thrombotic Material in Primary PCI: the ThrombOticBurden and mIcrovAscularobStruction (TOBIAS) Study.	Unknown status	NCT01914055	Phase 4
15	Effect of Gradual Reperfusion on Myocardial Edema and Coronary Microvascular Integrity in Patients Undergoing Primary Percutaneous Coronary Intervention	Unknown status	NCT02732080	Phase 4
16	Prospective RandomizEd Study Comparing Glycoprotein IIb/IIIa Inhibitors VERsus Standard Therapy in patientS With Myocardial Infarction and Angiographic Evidence of No-reFLOW	Unknown status	NCT02739711	Phase 4	Glycoprotein IIb/IIIa inhibitors
17	Study of Anti-inflammatory Treatment With Colchicine in the Acute Phase of ST-elevation Myocardial Infarction to Reduce Infarct Size	Unknown status	NCT01936285	Phase 4	Colchicine 2 mg loading dose; 0.5 mg bid for 5 days;Placebo
18	N-3 Fatty Acids for the Prevention of Atrial Fibrillation in Patients With Acute Heart Failure	Unknown status	NCT00692718	Phase 4	Epadel, Eicosapentaenoic acid
19	Imaging of Inflammation in the Postischemic Myocardium: Effect of Anti-inflammatory Treatment With Colchicine	Unknown status	NCT02281305	Phase 4	Colchicine
20	Evaluation of Neointimal Coverage of Everolimus-Eluting Stent and Bare-metal Stent After Implantation in STEMI Patients by Optical Coherence Tomography	Unknown status	NCT01875835	Phase 4
21	Randomized Controlled Study of a Rapid "Rule Out" Strategy Using CT Coronary Angiogram Versus Traditional Care for Low- to Intermediate-Risk ED Patients With Potential Acute Coronary Syndromes	Unknown status	NCT00933400	Phase 4
22	Effects of Sodium Tanshinone IIA Sulfonate on Left Ventricular Remodeling in Patients With ST-segment Elevation Myocardial Infarction Following Percutaneous Coronary Intervention	Unknown status	NCT02524964	Phase 4	sodium tanshinone IIA sulfonate
23	Treating Acute MI Patients With Aggrastat on Their Way to Hospital	Unknown status	NCT00300833	Phase 4	Tirofiban
24	The Effect of Tongguan Capsule for MicroRNA Profiles Between Qi-Stagnation and Qi-Deficiency in Coronary Heart Disease Patients With Blood Stasis Syndrome Undergoing Percutaneous Coronary Intervention	Unknown status	NCT02850627	Phase 4	Tongguan capsule;placebo capsule
25	A Prospective, Multicenter, Randomized, Open-label Trial to Compare Efficacy and Safety of Clopidogrel vs Ticagrelor in Stabilized Patients With Acute Myocardial Infarction After Percutaneous Coronary Intervention; TicAgrelor Versus CLOpidogrel in Stabilized Patients With Acute Myocardial Infarction: TALOS-AMI	Completed	NCT02018055	Phase 4	Aspirin+Ticagrelor;Aspirin+Clopidogrel
26	Phase 4 Study of Application of Intracoronary Low Dose Streptokinase Complementary to Standard Percutaneous Coronary Intervention in Patients With ST Elevation Acute Myocardial Infarction: Effect of Adjunctive Intracoronary Streptokinase on Late Term Left Ventricular Infarct Size and Volumes in Patients With Acute Myocardial Infarction	Completed	NCT00627809	Phase 4	Streptokinase
27	Effect of METOprolol in CARDioproteCtioN During an Acute Myocardial InfarCtion. The ME"Effect of METOprolol in CARDioproteCtioN During an Acute Myocardial InfarCtion" (METOCARD-CNIC): A Randomized, Controlled Parallel-group, Observer-blinded Clinical Trial of Early Pre-reperfusion Metoprolol Administration in ST-segment Elevation Myocardial infarctionTOCARD-CNIC Trial.	Completed	NCT01311700	Phase 4	Injectable (i.v.) metoprolol tartrate (up to 15 mg).
28	Tight Glycemic Control Increases Cardiac Stem Cells and Reduces Heart Remodeling During Acute Myocardial Infarction in Hyperglycemic Patients	Completed	NCT00863629	Phase 4	Insulin
29	Efficacy of Clotinab in Acute Myocardial Infarction Trial- ST Elevation Myocardial Infarction	Completed	NCT00841438	Phase 4	Clotinab
30	A Randomized Trial of Early Discharge After Trans-radial Stenting of Coronary Arteries in Acute Myocardial Infarction: The EASY-MI Pilot Study.	Completed	NCT00440778	Phase 4	Abciximab
31	Early Effect Of Bezafibrate On Fibrinogen Levels, Inflammatory Response And Clinical Impact, In Patients With ST Elevation Acute Myocardial Infarction	Completed	NCT02291796	Phase 4	Bezafibrate
32	Impact of Morphine Treatment on Platelet Inhibition in Acute Myocardial Infarction	Completed	NCT02627950	Phase 4	Morphinhydrochloricum;Metoclopramide;Ticagrelor;Isotonic sodium chloride
33	An International, Multicenter, Randomized Trial Assessing the Value of Mechanical Reperfusion in Patients With Acute Myocardial Infarction Presenting > 12 Hours From Onset of Symptoms	Completed	NCT00759629	Phase 4
34	Randomized Clinical Study of Intraaortic Balloon Pump Use in Cardiogenic Shock Complicating Acute Myocardial Infarction	Completed	NCT00491036	Phase 4
35	Prospective Randomized Multicenter Study Comparing Immediate Multivessel Revascularization by PCI Versus Culprit Lesion PCI With Staged Non-culprit Lesion Revascularization in Patients With Acute Myocardial Infarction Complicated by Cardiogenic Shock	Completed	NCT01927549	Phase 4
36	Bivalirudin in Acute Myocardial Infarction vs Glycoprotein IIb/IIIa and Heparin Undergoing Angioplasty (BRIGHT):a Randomised Controlled Trial	Completed	NCT01696110	Phase 4	Bivalirudin;heparin;heparin plus tirofiban
37	Efficacy and Safety of Individualized P2Y12 Receptor Antagonists Treatment Based on Agregometry Versus Fixed Dose Regimen in Patients After Acute Myocardial Infarction	Completed	NCT04369534	Phase 4	Clopidogrel;Ticagrelor
38	A Multi-center, Randomized, Controlled Study of Mechanical Left Ventricular Unloading With Counterpulsation to Reduce Infarct Size Pre-PCI for Acute Myocardial Infarction - CRISP AMI	Completed	NCT00833612	Phase 4
39	The Contrast Media and Nephrotoxicity Following Coronary Revascularization by Primary Angioplasty for Acute Myocardial Infarction. The CONTRAST-AMI Study.	Completed	NCT00827788	Phase 4	Iodixanol;Iopromide
40	Comparison of Administration of Tirofiban in the Ambulance or in the Cathlab in Patients With Acute Myocardial Infarction Treated With Primary Angioplasty	Completed	NCT00538317	Phase 4	tirofiban
41	Reversal of No-reflow/Slow-flow During Percutaneous Coronary Intervention in Patients With Acute Myocardial Infarction--a Prospective Randomized Study Comparing Intracoronary Infusion of Diltiazem, Verapamil and Nitroglycerin	Completed	NCT00712894	Phase 4	Diltiazem;Verapamil;Nitroglycerin
42	A Randomized Trial of Early Discharge After Trans-Radial Stenting of Coronary Arteries in Acute Myocardial Infarction and RESCUE-PCI: The EASY-RESCUE Pilot Study	Completed	NCT00440895	Phase 4	Abciximab
43	Comparison of Prasugrel and Ticagrelor in the Treatment of Acute Myocardial Infarction	Completed	NCT02808767	Phase 4	Prasugrel;Ticagrelor
44	Global Left Ventricular Function After Acute Myocardial Infarction. Treatment With the Angiotensin 2-Receptor Blocker Irbesartan	Completed	NCT00125645	Phase 4	Irbesartan Oral Tablet
45	Effects of Early Statin Treatment on Symptomatic Heart Failure and Ischemic Events After Acute Myocardial Infarction. The MUSASHI-AMI: A Multicenter Randomized Controlled Trial	Completed	NCT00128024	Phase 4	lipid-lowering treatment
46	The Effects of Eplerenone on Left Ventricular Remodelling Post-Acute Myocardial Infarction: a Double-Blind Placebo-Controlled Cardiac MR-Based Study	Completed	NCT00132093	Phase 4	Eplerenone
47	Phase 4 Study of the Effect of Human Recombinant Erythropoietin at the Time of Reperfusion in Patients With Acute Myocardial Infarction	Completed	NCT00882466	Phase 4	human recombinant erythropoietin
48	Pharmacokinetics and Pharmacodynamics of Platelet P2Y12 Inhibitors in Patients Undergoing Percutaneous Coronary Intervention (PCI) for Acute Myocardial Infarction: A Pilot Study	Completed	NCT02376283	Phase 4	Prasugrel;Clopidogrel;ticagrelor
49	Hyperglycemia and Its Effect After Acute Myocardial Infarction on Cardiovascular Outcomes in Patients With Type 2 Diabetes (HEART2D)	Completed	NCT00191282	Phase 4	Insulin lispro;Human insulin isophane suspension (NPH);Insulin glargine;Human insulin isophane suspension;Human insulin 30/70
50	A Multicenter Randomized Trial in the Prevention of Reocclusion Following Successful Thrombolysis for Suspected Acute Myocardial Infarction: An Invasive Versus a Conservative Strategy	Completed	NCT00138034	Phase 4

Search NIH Clinical Center for Acute Myocardial Infarction

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Genetic Tests for Acute Myocardial Infarction

Sources

Anatomical Context for Acute Myocardial Infarction

Organs/tissues related to Acute Myocardial Infarction:

MalaCards : Heart, Bone Marrow, Bone, Endothelial, Kidney, Brain, Neutrophil

Sources

Publications for Acute Myocardial Infarction

Articles related to Acute Myocardial Infarction:

(show top 50) (show all 35209)

#	Title	Authors	PMID	Year
1	Circulating MicroRNA-208b and MicroRNA-499 reflect myocardial damage in cardiovascular disease. ⁴⁶	Corsten MF...Schroen B	20921333	2010
2	Changes of matrix metalloproteinase-9 level is associated with left ventricular remodeling following acute myocardial infarction among patients treated with trandolapril, valsartan or both. ⁵³ ⁶²	Miyazaki S...Daida H	20378999	2010
3	Activation of peripheral blood mononuclear cells and extracellular matrix and inflammatory gene profile in acute myocardial infarction. ⁵³ ⁶²	Fang L...Dart AM	20388121	2010
4	Endothelin-1 release in acute myocardial infarction as a predictor of long-term prognosis and no-reflow assessed by contrast-enhanced magnetic resonance imaging. ⁵³ ⁶²	Eitel I...Thiele H	20435200	2010
5	Tissue plasminogen activator antigen predicts medium-term left ventricular end-systolic volume after acute myocardial infarction. ⁵³ ⁶²	Weir RA...Lowe GD	19662337	2010
6	Left ventricular function and C-reactive protein levels in acute myocardial infarction. ⁵³ ⁶²	Arruda-Olson AM...Roger VL	20346306	2010
7	Point-of-care test of heart-type fatty acid-binding protein for the diagnosis of early acute myocardial infarction. ⁵³ ⁶²	Li CJ...Huang J	20140003	2010
8	[The significance of the changes in expressions of heat shock protein 70 and heme oxygenase-1 in the myocardium in patients died suddenly due to acute myocardial infarction]. ⁵³ ⁶²	Zuo LP...Ma ZF	20170613	2010
9	Circulating p53 and cytochrome c levels in acute myocardial infarction patients. ⁵³ ⁶²	Dincer Y...Akcay T	19551350	2010
10	Noninvasive assessment of left ventricular filling pressure after acute myocardial infarction: a prospective study of the relative prognostic utility of clinical assessment, echocardiography, and B-type natriuretic peptide. ⁵³ ⁶²	Kruszewski K...Hillis GS	20102866	2010
11	Comparison of usefulness of heart-type fatty acid binding protein versus cardiac troponin T for diagnosis of acute myocardial infarction. ⁵³ ⁶²	Haltern G...Scheffold T	20102882	2010
12	Admission creatine kinase as a prognostic marker in acute myocardial infarction. ⁵³ ⁶²	Kazmi KA...Iqbal MP	20201171	2009
13	Plasma thrombomodulin activity, tissue factor activity and high levels of circulating procoagulant phospholipid as prognostic factors for acute myocardial infarction. ⁵³ ⁶²	Van Dreden P...Vasse M	19809306	2009
14	The profile of circulating metalloproteinases after PCI in patients with acute myocardial infarction or stable angina. ⁵³ ⁶²	Furenes EB...Seljeflot I	19410278	2009
15	TNF-alpha/IL-10 ratio and C-reactive protein as markers of the inflammatory response in CAD-prone North Indian patients with acute myocardial infarction. ⁵³ ⁶²	Goswami B...Kumar S	19576194	2009
16	Increased expression of TF on monocytes, but decreased numbers of TF bearing microparticles in blood from patients with acute myocardial infarction. ⁵³ ⁶²	Keuren JF...Leers MP	19558505	2009
17	The joint effects of apolipoprotein B, apolipoprotein A1, LDL cholesterol, and HDL cholesterol on risk: 3510 cases of acute myocardial infarction and 9805 controls. ⁵³ ⁶²	Parish S...International Studies of Infarct Survival Collaborators	19520708	2009
18	The aptamer ARC1779 is a potent and specific inhibitor of von Willebrand Factor mediated ex vivo platelet function in acute myocardial infarction. ⁵³ ⁶²	Spiel AO...Jilma B	19637097	2009
19	[Correlation between serum MMP-2 and MMP-9 in patients with acute myocardial infarction before and after PCI]. ⁵³ ⁶²	Dai F...Pan J	19664397	2009
20	Conjugation of biomolecules with magnetic protein microspheres for the assay of early biomarkers associated with acute myocardial infarction. ⁵³ ⁶²	Wang J...Zhang L	19555077	2009
21	Carboxylated magnetic microbead-assisted fluoroimmunoassay for early biomarkers of acute myocardial infarction. ⁵³ ⁶²	Wang J...Xu J	19398193	2009
22	The impact of admission C-reactive protein levels on the development of no-reflow phenomenon after primary PCI in patients with acute myocardial infarction: the role of inflammation. ⁵³ ⁶²	Celik T...Ozkan M	18579226	2009
23	Plasma TF activity predicts cardiovascular mortality in patients with acute myocardial infarction. ⁵³ ⁶²	Steppich BA...Ott I	19570241	2009
24	Association of C-reactive protein and HIV infection with acute myocardial infarction. ⁵³ ⁶²	Triant VA...Grinspoon SK	19387353	2009
25	Expressions of eNOS3 and Ve-cadherin in microvascular endothelium at 7-day of reperfused acute myocardial infarction. ⁵³ ⁶²	Kang S...Cheng YT	19519369	2009
26	[An angiographic trial to evaluate the efficacy and safety of tenecteplase in Chinese patients with acute myocardial infarction]. ⁵³ ⁶²	Liang F...Lu YL	19927632	2009
27	Superparamagnetic microsphere-assisted fluoroimmunoassay for rapid assessment of acute myocardial infarction. ⁵³ ⁶²	Wang J...Shang B	19394809	2009
28	[Study of association of platelet endothelial cell adhesion molecule-1 gene polymorphism with acute myocardial infarction]. ⁵³ ⁶²	Fu XL...Xia ZH	19570335	2009
29	C-terminal provasopressin (copeptin) is a strong prognostic marker in patients with heart failure after an acute myocardial infarction: results from the OPTIMAAL study. ⁵³ ⁶²	Voors AA...OPTIMAAL Investigators	19346228	2009
30	Human heart-type fatty acid-binding protein for on-site diagnosis of early acute myocardial infarction. ⁵³ ⁶²	Liao J...Renneberg R	18571749	2009
31	Levels of serum deoxyribonuclease I activity on admission in patients with acute myocardial infarction can be useful in predicting left ventricular enlargement due to remodeling. ⁵³ ⁶²	Kuribara J...Yasuda T	19304122	2009
32	[Coronary flow and hemorrhagic complications after alteplase and streptokinase administration in patients with acute myocardial infarction]. ⁵³ ⁶²	Kostic T...Vidanovic M	19341228	2009
33	[The relationship between plasma BNP level and the left ventricular dysfunction parameters in patients with acute myocardial infarction and it's value in diagonosing heart failure.]. ⁵³ ⁶²	Mao Y...Chen ZJ	19781144	2009
34	Impact of telmisartan on coronary stenting in patients with acute myocardial infarction compared with enalapril. ⁵³ ⁶²	Yokoyama J...Okumura K	18190989	2009
35	The relationship of plasminogen activator inhibitor-1 levels to the ST deviation pattern of acute myocardial infarction. ⁵³ ⁶²	Rott D...Urieli-Shoval S	18580060	2009
36	Admission levels of C-reactive protein and plasminogen activator inhibitor-1 in patients with acute myocardial infarction with and without cardiogenic shock or heart failure on admission. ⁵³ ⁶²	Akkus MN...Sucu N	19246845	2009
37	Factors associated with C-reactive protein at the early stage of acute myocardial infarction in men. ⁵³ ⁶²	Piestrzeniewicz K...Goch JH	19130414	2009
38	Plasma adiponectin and resistin levels as predictors of mortality in patients with acute myocardial infarction: data from infarction prognosis study registry. ⁵³ ⁶²	Lee SH...Chung N	18997620	2009
39	Acute phase proteins and systolic dysfunction in subjects with acute myocardial infarction. ⁵³ ⁶²	Brunetti ND...Di Biase M	18038115	2008
40	[Plasma tissue factor and tissue factor pathway inhibitor levels in acute myocardial infarction patients with no-reflow during percutaneous coronary intervention]. ⁵³ ⁶²	Xu P...Wang WL	19102916	2008
41	Impact of plaque rupture and elevated C-reactive protein on clinical outcome in patients with acute myocardial infarction: an intravascular ultrasound study. ⁵³ ⁶²	Hong YJ...Weissman NJ	18762670	2008
42	Acute myocardial infarction as a systemic prothrombotic condition evidenced by increased von Willebrand factor protein over ADAMTS13 activity in coronary and systemic circulation. ⁵³ ⁶²	Horii M...Saito Y	18810578	2008
43	Dysregulation of microRNAs after myocardial infarction reveals a role of miR-29 in cardiac fibrosis. ⁴⁶	van Rooij E...Olson EN	18723672	2008
44	Relationship of sustained brain natriuretic peptide release after reperfused acute myocardial infarction with gated SPECT infarct measurements and its connection with collagen turnover and left ventricular remodeling. ⁵³ ⁶²	Cerisano G...Antoniucci D	18761267	2008
45	[Comparative effect of streptokinase and alteplase on electrocardiogram and angiogram signs of myocardial reperfusion in ST segment elevation acute myocardial infarction]. ⁵³ ⁶²	Tomasevic M...Salinger-Martinovic S	19069338	2008
46	Value of blood adipose tissue hormones concentration--adiponectin, resistin and leptin in the prediction of major adverse cardiac events (MACE) in 1-year follow-up after primary percutaneous coronary intervention in ST-segment elevation acute myocardial infarction. ⁵³ ⁶²	Piestrzeniewicz K...Goch JH	18766137	2008
47	A close relationship between functional polymorphism in the promoter region of matrix metalloproteinase-9 and acute myocardial infarction. ⁵³ ⁶²	Koh YS...Choi KB	17698228	2008
48	[Role of nuclear factor-KappaB in endothelial injury in acute myocardial infarction]. ⁵³ ⁶²	Liao XX...Ma H	18611340	2008
49	Value of brain natriuretic peptide after acute myocardial infarction. ⁵³ ⁶²	Gunes Y...Karcier S	18524723	2008
50	Late ventricular remodeling in non-reperfused acute myocardial infarction in humans is predicted by angiotensin II type 1 receptor density on blood platelets. ⁵³ ⁶²	Maczewski M...Wojciechowski D	17651844	2008

Sources

Genes for Acute Myocardial Infarction

Genes related to Acute Myocardial Infarction (2 elite genes):

(show top 50) (show all 76)

- Elite gene

- Cancer Census gene in COSMIC

#	Symbol	Description	Category	Score	Evidence	PubMed IDs
1	MIR208B	MicroRNA 208b	RNA Gene	368.88	Causal ⁴⁶ DISEASES inferred ¹⁴ ¹⁴ GeneCards inferred via : Publications (show sections)	20921333
2	MIR499A	MicroRNA 499a	RNA Gene	368.47	Causal ⁴⁶ DISEASES inferred ¹⁴ ¹⁴ GeneCards inferred via : Publications (show sections)	20921333
3	CDKN2B-AS1	CDKN2B Antisense RNA 1	RNA Gene	155.47	Experimental evidence ³⁷ DISEASES inferred ¹⁴	25035150
4	MHRT	Myosin Heavy Chain Associated RNA Transcript	RNA Gene	155.46	Experimental evidence: Expression ³⁷ DISEASES inferred ¹⁴	26759697
5	KCNQ1OT1	KCNQ1 Opposite Strand/Antisense Transcript 1	RNA Gene	154.74	Experimental evidence ³⁷ DISEASES inferred ¹⁴	25035150
6	UCA1	Urothelial Cancer Associated 1	RNA Gene	154.28	Experimental evidence: Expression ³⁷ DISEASES inferred ¹⁴	26949706
7	SLC16A1-AS1	SLC16A1 Antisense RNA 1	RNA Gene	150	Experimental evidence: Regulation ³⁷	28418905
8	TNFRSF14-AS1	TNFRSF14 Antisense RNA 1	RNA Gene	150	Experimental evidence: Regulation ³⁷	28418905
9	MIR29A	MicroRNA 29a	RNA Gene	55.58	Unspecified ⁴⁶ DISEASES inferred ¹⁴	18723672
10	PLAT	Plasminogen Activator, Tissue Type	Protein Coding	38.31	DISEASES inferred ¹⁴ Novoseek inferred ⁵³ GeneCards inferred via : Publications Proteins (show sections)	7623530 7588083 7942523 (more) 9786806 8790022 15159721 19069338 9180103 10859283 14982910 1832058 1829574 9761098 10172669 1590225 1512327 11122543 10572811 9340503 8402755 11533504 10575530 9034237 12001538 10171541 1746456 1971034 8277097 1909151 19341228 17371644 10475182 11593632 9778080 1901466 1975322 2116935 15194014 15077097 14715345 12851604 12355031 11353931 10922430 10200858 10024933 9200390 1922986 15353917 12595837 8521760 1289101 7488444 11425410 11102251 11950430 10067269 9555772 18020578 10362188 9892272 9070549 8542868 1315073 1372625 2121199 1975321 1527286 1537129 9340504 9244730 8960443 2119264 2198644 2125681 1914361 1746449 7747700 8712112 10474793 10614792 9465840 9426026 9352981 9179619 8994745 8970403 8888101 2121487 2119970 2114788 8554497 19927632 16143058 17145060 16234788 12679759 7547005 7895348
11	IDH2	Isocitrate Dehydrogenase (NADP(+)) 2	Protein Coding	27.83	Risk factor ⁵ DISEASES inferred ¹⁴
12	ACE	Angiotensin I Converting Enzyme	Protein Coding	27.67	DISEASES inferred ¹⁴ Novoseek inferred ⁵³ GeneCards inferred via : Publications (show sections)	9416888 8950065 15262665 (more) 15520426 9515282 12241832 8429112 8212605 8565174 15643463 16683215 9180106 2189622 12514658 9704689 11356434 12423701 8749270 10569326 8535052 17969373 11772121 9429845 7588920 14707020 9631869 19505282 15187573 12766124 10406358 18215613 8749267 1746415 8465457 10622114 11079227 16088849 8076657 8070480 8125422 8224926 18190989 18501888 17461873 16380023 16485515 10399995 10220542 10088066 9825077 9797884 9443424 9431480 9364295 9289944 7769497 7827370 8331801 17875946 15826580 16784910 16247204 15886979 15277998 10860176 9595001 9553407 9594263 8759064 8542881 7634266 8143299 8104243 11792333 11881032 8329800 1668233 20378999 16767569 16259523 15785027 15034703 12556670 10552190 9422854 9218207 9193426 9167457 8996294 9023710 7774515 12852701 12614193 12591842 11504163 11252112 11728260 10895836 10698231
13	MB	Myoglobin	Protein Coding	26.94	DISEASES inferred ¹⁴ Novoseek inferred ⁵³ GeneCards inferred via : Publications (show sections)	15226704 1489857 9127740 (more) 11571240 8198879 9351728 10650227 9267316 15226628 8144762 15897132 15049381 10581334 9034351 17084941 11113415 11129678 10872705 9570438 9539485 8800429 17982968 8787704 7785657 7888482 2108824 1467029 7656437 1414933 8174583 10929237 15464666 2372186 8444499 16827225 12760310 12515148 10499688 10451248 10078116 10073855 9635105 9581858 17571610 16374655 16309372 16243197 15641689 11832985 11431653 10483955 10726820 15301894 12649923 10966533 10666352 9810342 9648898 9489972 9352127 9294666 11557246 11486476 9857933 7578616 7664479 7704948 7919591 2095000 18036357 17306781 11793431 11113416 10690308 9919744 9626826 9587170 10909799 9439877 9055056 8727630 8092598 2284744 18945609 17584670 16319659 9204206 9148993 9110006 7980735 8498383 1450222 1805054 19681456 9461704 9086293 8521560 7930658 1413198
14	CRP	C-Reactive Protein	Protein Coding	25.73	DISEASES inferred ¹⁴ Novoseek inferred ⁵³ GeneCards inferred via : Publications (show sections)	16000887 10687251 8615301 (more) 8994423 9270121 15504106 17489343 16146596 11305531 16642000 12422145 16703188 11216827 11427220 11502046 11792332 12796768 15208795 15539707 15764760 19587606 19842447 17693973 16916504 17100670 15374783 15049386 12930233 11367525 19387353 19246845 19130414 18762670 15658646 12024080 11890369 19690638 18392101 14577520 14566035 14502382 12756602 12006411 10925350 18038115 16931161 11558844 17666352 17125041 16443738 16803998 16541617 12835218 12193848 9352376 19576194 16787196 15852896 15469788 15199348 14602213 11557253 10652189 10393687 18579226 16897925 16237952 15882661 15550024 16140308 16543633 15587759 15255461 15187573 12804927 15312863 12760265 12714206 12686330 12589119 20138585 19642911 19610570 18317426 17921916 16286731 15529571 11156347 10090530 9479940 20346306 15893172 16115487 16449211 16516078 18940277 18584898 19585221
15	FABP3	Fatty Acid Binding Protein 3	Protein Coding	25.44	DISEASES inferred ¹⁴ Novoseek inferred ⁵³ GeneCards inferred via : Publications (show sections)	1480144 16035729 16827225 (more) 15641689 20102882 17982968 10905760 20140003 14581522 19555077 20391015 18968649 18412949 17097752 7541428 7919591 19475367 18393112 17894935 14745150 16293913 15704065 19398193 16182485 11305642 10794758 18571749 17392813 12969550 19394809 15951316 11440724 18992232 14975559
16	NPPB	Natriuretic Peptide B	Protein Coding	25.25	DISEASES inferred ¹⁴ Novoseek inferred ⁵³ GeneCards inferred via : Publications (show sections)	8319360 17084941 9547443 (more) 9918892 18761267 15545516 9922344 11310490 16697117 15609694 18419951 9453517 17891611 12667002 1834057 15361283 8337997 16360361 18524723 19781144 16626544 7850823 8718658 10464838 10763077 17007238 19346228 17663815 17066622 16538011 16616016 15618053 15261928 15163931 17151299 15019872 14658407 11711456 16297365 15827538 15056825 9505917 9284403 8282365 17317366 15516817 12974669 12771003 11957795 11558681 7664440 17986844 19766750 17121728 10881579 10859990 10737768 19642911 19189316 19447837 16886494 16269246 15929819 11021766 9688434 8613267 7588920 15353502 12875490 20102866 8759805 16776957 16361163 17639095
17	PIK3C2A	Phosphatidylinositol-4-Phosphate 3-Kinase Catalytic Subunit Type 2 Alpha	Protein Coding	25.04	DISEASES inferred ¹⁴ Novoseek inferred ⁵³ GeneCards inferred via : Publications (show sections)	1842714 15815362 9778551 (more) 10522418 10663915 9461704 11680269 10721642 7710160 18442010 8762692 8069015 7971491 1843508 1825742 18002105 12839046 2333401 17571610 10392484 1784801 8026351 10051074 11041123
18	TNNT2	Troponin T2, Cardiac Type	Protein Coding	24.25	DISEASES inferred ¹⁴ Novoseek inferred ⁵³ GeneCards inferred via : Publications (show sections)	12649923 9857757 17926199 (more) 9028628 8890819 10094373 9470339 11587129 9110006
19	TNNI3	Troponin I3, Cardiac Type	Protein Coding	23.67	DISEASES inferred ¹⁴ Novoseek inferred ⁵³ GeneCards inferred via : Publications (show sections)	7656437 11587129 9028628
20	F3	Coagulation Factor III, Tissue Factor	Protein Coding	23.13	DISEASES inferred ¹⁴ Novoseek inferred ⁵³ GeneCards inferred via : Publications (show sections)	9812083 8598077 11535724 (more) 11555704 15033248 15472641 15731537 8952863 10520779 15213859 9453518 7923646 19558505 16377278 1746002 19809306 15199481 19570241 15630488 14558284 12458393 11969277 11334654 9894705 9313605 1623119 17249334 11127875 10518365 19102916 18158992 7923650 15496651 19237657 1607535 8279364
21	SELP	Selectin P	Protein Coding	22.83	DISEASES inferred ¹⁴ Novoseek inferred ⁵³ GeneCards inferred via : Publications (show sections)	14640893 16767965 11461745 (more) 9485126 7524972 9546964 9672405 7519556 8574460 16382754 9822864 16756193 16019467 12458392 10650306 19850970 12960610 11353931 9799011 16824841 19264679 16323552 12361207 9783645 16154181 15568145 7540229 10833791 10393398 10399997 12957760
22	SERPINE1	Serpin Family E Member 1	Protein Coding	22.7	DISEASES inferred ¹⁴ Novoseek inferred ⁵³ GeneCards inferred via : Publications (show sections)	8402755 9736130 9474013 (more) 19930866 16845251 19246845 11567664 16706983 10894435 11918281 11289708 10952148 1832058 8642503 11714998 8130023 12412817 18607173 7585744 12360174 18580060 16916501 2123906 19844663 19809306 12208595 1287882 1815876 9136593 8217070 12441914 8891805 8819256 8407726 12682447 12214153 11666090 11129670 8773432 8107282 16307159 12801613 11041123 12685623 17126309
23	NPPA	Natriuretic Peptide A	Protein Coding	22.45	DISEASES inferred ¹⁴ Novoseek inferred ⁵³ GeneCards inferred via : Publications (show sections)	8515566 8519004 17964349 (more) 8127791 1829681 9922344 2146863 8404931 8731859 1387544 1840330 9259165 8111772 1837318 11401117 8197967 8282365 17291931 7588920 8507921 8319360 9527094 14745141 7606640 2141224 18490430 1834057 16297365 14607848 9284403 8958191 8174145 8164338 8337997 9688434 12974669 11558681 9453517 7664440 8313544 1838000 1825742 12736485 8640969 8636550 8613267 8545147 2151320 9103159 7850823 8281531 10926626 10859990 10622548 1289594 2146121 2140009 16269246 15609694 17151299 17326075 8237747 9570436 12212118 8759805 2149534
24	SERPINC1	Serpin Family C Member 1	Protein Coding	22.15	DISEASES inferred ¹⁴ Novoseek inferred ⁵³ GeneCards inferred via : Publications (show sections)	1831932 9247044 9875108 (more) 15309006 8778585 1711506 9498539 10502216 10793178 15670549 1815877 8899153 9191478 9486929 10099038 10158385 14642154 15566913
25	SERPINF2	Serpin Family F Member 2	Protein Coding	21.45	DISEASES inferred ¹⁴ Novoseek inferred ⁵³ GeneCards inferred via : Publications (show sections)	8261210 1691750
26	EDN1	Endothelin 1	Protein Coding	20.86	DISEASES inferred ¹⁴ Novoseek inferred ⁵³ GeneCards inferred via : Publications (show sections)	17507790 8438694 10451230 (more) 16313114 16829540 15309013 1725389 9441724 11770304 15161426 8519005 8522408 9857278 8803588 18076360 15342298 9057069 1480507 1725426 17241184 9782065 8969576 7618758 1467630 17893002 15888819 15888812 12581682 20435200 16733909 12212118 9570436 9736439
27	MMP9	Matrix Metallopeptidase 9	Protein Coding	20.79	DISEASES inferred ¹⁴ Novoseek inferred ⁵³ GeneCards inferred via : Publications (show sections)	15309700 18035073 12824721 (more) 17698228 18653544 16500583 18442010 19664397 18501888 16195613 9708462 11174334 18068618 17727318 15118287 18298349 16493496 14577520 20514777 17339265 16080811 15265816 16723786 16830792 20378999 20388121 18263717 19410278
28	VWF	Von Willebrand Factor	Protein Coding	20.52	DISEASES inferred ¹⁴ Novoseek inferred ⁵³ GeneCards inferred via : Publications (show sections)	11113268 10959690 8891805 (more) 1530813 9950656 18810578 8070473 16190382 1908371 19637097 9826309 9241740 16377278 17719316 7811156 18295305 16154181 19662337 15033248
29	HFE	Homeostatic Iron Regulator	Protein Coding	20.51	DISEASES inferred ¹⁴ GeneCards inferred via : Disorders Publications (show sections)
30	MYL3	Myosin Light Chain 3	Protein Coding	19.73	DISEASES inferred ¹⁴ Novoseek inferred ⁵³ GeneCards inferred via : Publications (show sections)	8254402 7988046 7704948
31	CKB	Creatine Kinase B	Protein Coding	19.57	DISEASES inferred ¹⁴ Novoseek inferred ⁵³ GeneCards inferred via : Publications (show sections)	8120516 1511070 2096250
32	CDH5	Cadherin 5	Protein Coding	18.8	DISEASES inferred ¹⁴ Novoseek inferred ⁵³ GeneCards inferred via : Publications (show sections)	19519369 14695457
33	PTX3	Pentraxin 3	Protein Coding	18.76	DISEASES inferred ¹⁴ Novoseek inferred ⁵³ GeneCards inferred via : Publications (show sections)	10931803 17095712 12006411 (more) 12006390 15226367
34	AGTR1	Angiotensin II Receptor Type 1	Protein Coding	18.49	DISEASES inferred ¹⁴ Novoseek inferred ⁵³ GeneCards inferred via : Publications (show sections)	15543360 14999200 16998258 (more) 12614193 16911325 17651844 14574083
35	FGA	Fibrinogen Alpha Chain	Protein Coding	18.44	DISEASES inferred ¹⁴ Novoseek inferred ⁵³ GeneCards inferred via : Publications (show sections)	1832058 12876638 7583543 (more) 1774011 8026047 9893733 8741240 10342131
36	APOB	Apolipoprotein B	Protein Coding	18.17	DISEASES inferred ¹⁴ Novoseek inferred ⁵³ GeneCards inferred via : Publications (show sections)	11755609 1516192 19520708 (more) 16734179 18701171 7889438
37	APOA1	Apolipoprotein A1	Protein Coding	18.16	DISEASES inferred ¹⁴ Novoseek inferred ⁵³ GeneCards inferred via : Publications (show sections)	11755609 1673162 9845859 (more) 10559518 14975545 16734179 19520708 9336872 7671890
38	PAPPA	Pappalysin 1	Protein Coding	17.89	DISEASES inferred ¹⁴ Novoseek inferred ⁵³ GeneCards inferred via : Publications (show sections)	11586954 19410278 20515576 (more) 19101225 16706128 19771323 17700210 18377765 12626203 15642282
39	CA3	Carbonic Anhydrase 3	Protein Coding	17.83	DISEASES inferred ¹⁴ Novoseek inferred ⁵³ GeneCards inferred via : Publications (show sections)	8572443 14559123 2108824
40	ITGA2B	Integrin Subunit Alpha 2b	Protein Coding	17.66	DISEASES inferred ¹⁴ Novoseek inferred ⁵³ GeneCards inferred via : Publications (show sections)	8187810
41	OLR1	Oxidized Low Density Lipoprotein Receptor 1	Protein Coding	17.55	DISEASES inferred ¹⁴ Novoseek inferred ⁵³ GeneCards inferred via : Publications (show sections)	16251892 15976314 16724009 (more) 14684693
42	PECAM1	Platelet And Endothelial Cell Adhesion Molecule 1	Protein Coding	17.51	DISEASES inferred ¹⁴ Novoseek inferred ⁵³ GeneCards inferred via : Publications (show sections)	9888878 19570335 9799011
43	THBD	Thrombomodulin	Protein Coding	17.46	DISEASES inferred ¹⁴ Novoseek inferred ⁵³ GeneCards inferred via : Publications (show sections)	16307806 11245641 7543831 (more) 18611340 9826309 19809306 14715348
44	SELE	Selectin E	Protein Coding	17.46	DISEASES inferred ¹⁴ Novoseek inferred ⁵³ GeneCards inferred via : Publications (show sections)	12605758 9335404 8655256 (more) 9527091 8821773 14640893 9359556 10925338 9314203 11353931 16205449 14624050 10090530 14750416
45	ADM	Adrenomedullin	Protein Coding	17.41	DISEASES inferred ¹⁴ Novoseek inferred ⁵³ GeneCards inferred via : Publications (show sections)	9536921 11115426 15670621 (more) 15927712 17081364 12445878 15609694 15262849 19804168 15678254 9505917 17878224 15464589 11798767 8721638
46	CKM	Creatine Kinase, M-Type	Protein Coding	17.18	DISEASES inferred ¹⁴ Novoseek inferred ⁵³ GeneCards inferred via : Publications (show sections)	7656437
47	PF4	Platelet Factor 4	Protein Coding	16.95	DISEASES inferred ¹⁴ Novoseek inferred ⁵³ GeneCards inferred via : Publications (show sections)	11712446 7737755
48	HMGCR	3-Hydroxy-3-Methylglutaryl-CoA Reductase	Protein Coding	16.76	DISEASES inferred ¹⁴ Novoseek inferred ⁵³ GeneCards inferred via : Publications (show sections)	15260513 11828605 10512503 (more) 11244205 17721009 14728000 14727994 10618584
49	IL6	Interleukin 6	Protein Coding	16.65	DISEASES inferred ¹⁴ GeneCards inferred via : Publications (show sections)
50	F7	Coagulation Factor VII	Protein Coding	16.47	DISEASES inferred ¹⁴ Novoseek inferred ⁵³ GeneCards inferred via : Publications (show sections)	17008590

Sources

Variations for Acute Myocardial Infarction

ClinVar genetic disease variations for Acute Myocardial Infarction:

⁵

#	Gene	Name	Type	Significance	ClinVarId	dbSNP ID	Position
1	IDH2	NM_002168.4(IDH2):c.516G>C (p.Arg172Ser)	SNV	Risk Factor	375985	rs1057519736	GRCh37: 15:90631837-90631837 GRCh38: 15:90088605-90088605
2	IDH2	NM_002168.4(IDH2):c.515G>T (p.Arg172Met)	SNV	Risk Factor	375986	rs121913503	GRCh37: 15:90631838-90631838 GRCh38: 15:90088606-90088606
3	IDH2	NM_002168.4(IDH2):c.515G>A (p.Arg172Lys)	SNV	Risk Factor	375987	rs121913503	GRCh37: 15:90631838-90631838 GRCh38: 15:90088606-90088606
4	IDH2	NM_002168.4(IDH2):c.514A>T (p.Arg172Trp)	SNV	Risk Factor	376438	rs1057519906	GRCh37: 15:90631839-90631839 GRCh38: 15:90088607-90088607

Copy number variations for Acute Myocardial Infarction from CNVD:

⁶

#	CNVD ID	Chromosome	Start	End	Type	Gene Symbol	CNVD Disease
1	210497	6	30400000	36600000	Amplification	C4B	Acute myocardial infarction

Sources

Expression for Acute Myocardial Infarction

Genes differentially expressed in tissues of Acute Myocardial Infarction patients vs. healthy controls: ³⁵

#	Gene	Description	Tissue	Up/Dn	Fold Change (log2)	P value
1	EGR3	early growth response 3	Blood	+	5.52	0.000
2	CXCL8	C-X-C motif chemokine ligand 8	Blood	+	3.51	0.004
3	LEP	leptin	Heart	+	3.45	0.011
4	ID1	inhibitor of DNA binding 1	Blood	+	3.18	0.007