MCID: ACT075
MIFTS: 58

Acute Myocardial Infarction

Categories: Cardiovascular diseases, Genetic diseases

Aliases & Classifications for Acute Myocardial Infarction

MalaCards integrated aliases for Acute Myocardial Infarction:

Name: Acute Myocardial Infarction 38 12 55 15 73

Classifications:



External Ids:

Disease Ontology 12 DOID:9408
ICD10 33 I21.3 I21
ICD9CM 35 410 410.9 410.90
NCIt 50 C35204
UMLS 73 C0155626

Summaries for Acute Myocardial Infarction

MalaCards based summary : Acute Myocardial Infarction is related to acute anterolateral myocardial infarction and cardiogenic shock, and has symptoms including angina pectoris and chest pain. An important gene associated with Acute Myocardial Infarction is MIR499A (MicroRNA 499a
In plasma from acute myocardial infarction (AMI) patients, cardiac myocyte-associated miRs-499 was highly elevated, 100-fold (p ), and among its related pathways/superpathways are Dilated cardiomyopathy (DCM) and A-beta Pathways: Plaque Formation and APP Metabolism. The drugs Pravastatin and Abciximab have been mentioned in the context of this disorder. Affiliated tissues include heart, bone and bone marrow, and related phenotypes are cardiovascular system and muscle

Related Diseases for Acute Myocardial Infarction

Diseases in the Myocardial Infarction family:

Myocardial Infarction 2 Acute Myocardial Infarction
Posterior Myocardial Infarction

Diseases related to Acute Myocardial Infarction via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50) (show all 314)
# Related Disease Score Top Affiliating Genes
1 acute anterolateral myocardial infarction 33.4 ACE PIK3C2A
2 cardiogenic shock 32.4 CRP NPPB PIK3C2A PLAT
3 angina pectoris 32.3 ACE CRP F3
4 cardiac rupture 32.0 CRP PLAT
5 myocarditis 31.9 MB NPPB TNNI3
6 coronary stenosis 31.9 ACE CRP TNNI3
7 cardiac arrest 31.7 ACE PIK3C2A TNNT2
8 atrial fibrillation 31.7 ACE ADRB1 NPPB PLAT
9 coronary heart disease 1 31.6 ACE ADRB1 CRP
10 ischemic heart disease 31.5 ACE CRP NPPB
11 congenitally corrected transposition of the great arteries 31.5 NPPB TNNT2
12 pericarditis 31.4 CRP NPPB TNNT2
13 sleep apnea 31.4 ACE CRP NPPB
14 endocarditis 31.3 CRP PIK3C2A PLAT TNNI3
15 pulmonary edema 31.3 ACE CRP NPPB PIK3C2A
16 coronary restenosis 31.3 ACE PLAT
17 arteries, anomalies of 31.2 ACE CRP F3 MB NPPB PLAT
18 disseminated intravascular coagulation 31.1 F3 MB PIK3C2A PLAT
19 systolic heart failure 31.1 ACE ADRB1 CRP NPPB
20 cerebrovascular disease 31.0 ACE CRP PLAT
21 pericardial effusion 31.0 CRP NPPB PIK3C2A
22 toxic myocarditis 31.0 NPPB PIK3C2A TNNI3
23 peripheral vascular disease 31.0 ACE CRP F3 PLAT
24 arteriosclerosis 30.9 ACE CRP F3
25 respiratory failure 30.8 ACE CRP F3 PIK3C2A
26 vascular disease 30.8 ACE CRP F3 PLAT
27 dressler's syndrome 30.5 CRP PLAT
28 myocardial infarction 30.5 ACE ADRB1 CDKN2B-AS1 CRP F3 FABP3
29 intermediate coronary syndrome 30.3 ACE CRP F3 MB PIK3C2A PLAT
30 chronic kidney failure 30.3 ACE CRP NPPB
31 pulmonary embolism 30.2 CRP F3 FABP3 NPPB PLAT TNNI3
32 congestive heart failure 30.0 ACE ADRB1 CDKN2B-AS1 NPPB PIK3C2A
33 stroke, ischemic 29.5 ACE CDKN2B-AS1 CRP F3 PLAT
34 heart disease 29.3 ACE ADRB1 CRP F3 FABP3 MHRT
35 diabetes mellitus, noninsulin-dependent 28.9 ACE CDKN2B-AS1 CRP MIR29A PLAT
36 coronary artery anomaly 28.8 ACE ADRB1 CDKN2B-AS1 CRP F3 FABP3
37 subendocardial infarction acute myocardial infarction 12.2
38 strictly posterior acute myocardial infarction 12.2
39 coronary artery disease, autosomal dominant, 1 11.3
40 acute inferoposterior infarction 11.2
41 acute inferolateral myocardial infarction 11.2
42 coronary artery disease, autosomal dominant 2 11.1
43 hyperlipoproteinemia, type iii 11.1
44 generalized atherosclerosis 11.1 ACE CRP
45 familial isolated restrictive cardiomyopathy 11.1 TNNI3 TNNT2
46 virus associated hemophagocytic syndrome 11.1 MB PIK3C2A
47 chronic thromboembolic pulmonary hypertension 11.1 CRP NPPB
48 heart conduction disease 11.1 ACE CRP NPPB
49 tick paralysis 11.0 PIK3C2A TNNI3
50 inferior myocardial infarction 11.0 NPPB PIK3C2A PLAT

Comorbidity relations with Acute Myocardial Infarction via Phenotypic Disease Network (PDN): (show all 22)


Active Peptic Ulcer Disease Acute Cystitis
Acute Kidney Failure Aortic Valve Disease 1
Cardiac Arrest Chronic Kidney Failure
Chronic Myocardial Ischemia Decubitus Ulcer
Deficiency Anemia Familial Atrial Fibrillation
Generalized Atherosclerosis Heart Disease
Hypertension, Essential Intermediate Coronary Syndrome
Ischemic Heart Disease Kidney Disease
Mitral Valve Disease Peripheral Vascular Disease
Protein-Energy Malnutrition Respiratory Failure
Schizophreniform Disorder Transient Cerebral Ischemia

Graphical network of the top 20 diseases related to Acute Myocardial Infarction:



Diseases related to Acute Myocardial Infarction

Symptoms & Phenotypes for Acute Myocardial Infarction

UMLS symptoms related to Acute Myocardial Infarction:


angina pectoris, chest pain

MGI Mouse Phenotypes related to Acute Myocardial Infarction:

46
# Description MGI Source Accession Score Top Affiliating Genes
1 cardiovascular system MP:0005385 9.65 ACE ADRB1 CRP F3 FABP3 MB
2 muscle MP:0005369 9.17 TNNI3 TNNT2 ADRB1 F3 FABP3 MB

Drugs & Therapeutics for Acute Myocardial Infarction

Drugs for Acute Myocardial Infarction (from DrugBank, HMDB, Dgidb, PharmGKB, IUPHAR, NovoSeek, BitterDB):

(show top 50) (show all 540)
# Name Status Phase Clinical Trials Cas Number PubChem Id
1
Pravastatin Approved Phase 4 81093-37-0 54687
2
Abciximab Approved Phase 4,Phase 3,Phase 2,Not Applicable 143653-53-6
3
Everolimus Approved Phase 4,Phase 3,Phase 2,Phase 1,Not Applicable 159351-69-6 6442177
4
Miconazole Approved, Investigational, Vet_approved Phase 4,Phase 2,Phase 3,Phase 1,Not Applicable 22916-47-8 4189
5
Sirolimus Approved, Investigational Phase 4,Phase 3,Phase 2,Phase 1,Not Applicable 53123-88-9 5284616 6436030 46835353
6
Aspirin Approved, Vet_approved Phase 4,Phase 3,Phase 2,Not Applicable 50-78-2 2244
7
Clopidogrel Approved Phase 4,Phase 3,Phase 2,Not Applicable 120202-66-6, 113665-84-2 60606
8
Thrombin Approved, Investigational Phase 4
9
Bivalirudin Approved, Investigational Phase 4,Phase 3,Not Applicable 128270-60-0 16129704
10
Enoxaparin Approved Phase 4,Phase 3,Phase 2,Not Applicable 9005-49-6 772
11
Tenecteplase Approved Phase 4,Phase 3,Phase 2 191588-94-0
12
Tirofiban Approved Phase 4,Phase 3,Not Applicable 144494-65-5 60947
13
Colchicine Approved Phase 4,Phase 3,Phase 2 64-86-8 6167 2833
14
Ticagrelor Approved Phase 4,Phase 3,Phase 2,Not Applicable 274693-27-5 9871419
15
Ticlopidine Approved Phase 4,Phase 3 55142-85-3 5472
16
Heparin Approved, Investigational Phase 4,Phase 3,Not Applicable 9005-49-6 772 46507594
17
Nicorandil Approved, Investigational Phase 4,Phase 3,Not Applicable 65141-46-0 47528
18
Desflurane Approved Phase 4 57041-67-5 42113
19
Isoflurane Approved, Vet_approved Phase 4 26675-46-7 3763
20
Propofol Approved, Investigational, Vet_approved Phase 4,Not Applicable 2078-54-8 4943
21
Insulin Glargine Approved Phase 4,Phase 3,Not Applicable 160337-95-1
22
Metformin Approved Phase 4,Phase 2,Phase 3 657-24-9 14219 4091
23
Zinc Approved, Investigational Phase 4,Phase 3,Phase 2,Phase 1,Not Applicable 7440-66-6 23994
24
Menthol Approved Phase 4,Phase 2,Phase 3,Not Applicable 2216-51-5 16666
25
Omeprazole Approved, Investigational, Vet_approved Phase 4 73590-58-6 4594
26
Pantoprazole Approved Phase 4 102625-70-7 4679
27
Angiotensin II Approved, Investigational Phase 4,Phase 3,Phase 2,Not Applicable 68521-88-0, 4474-91-3, 11128-99-7 172198 65143
28
Valsartan Approved, Investigational Phase 4,Phase 3 137862-53-4 60846
29
Dalteparin Approved Phase 4,Phase 3,Not Applicable 9005-49-6
30
Metoprolol Approved, Investigational Phase 4,Phase 3,Phase 1,Not Applicable 37350-58-6, 51384-51-1 4171
31
Lenograstim Approved, Investigational Phase 4,Phase 2,Phase 3,Phase 1 135968-09-1
32
Paclitaxel Approved, Vet_approved Phase 4,Phase 2,Phase 3,Not Applicable 33069-62-4 36314
33
Simvastatin Approved Phase 4,Phase 3,Phase 2 79902-63-9 54454
34
Adenosine Approved, Investigational Phase 4,Phase 3,Phase 2,Not Applicable 58-61-7 60961
35
Amlodipine Approved Phase 4,Phase 3 88150-42-9 2162
36
Rivaroxaban Approved Phase 4,Phase 3 366789-02-8
37
Chromium Approved Phase 4,Phase 3,Phase 2,Not Applicable 7440-47-3 27668
38
Warfarin Approved Phase 4,Phase 3,Not Applicable 81-81-2 6691 54678486
39
Bezafibrate Approved, Investigational Phase 4 41859-67-0 39042
40
Streptokinase Approved, Investigational Phase 4,Phase 3 9002-01-1
41
Benzocaine Approved, Investigational Phase 4,Phase 2,Phase 3,Not Applicable 1994-09-7, 94-09-7 2337
42
Diltiazem Approved, Investigational Phase 4,Not Applicable 42399-41-7 39186
43
Nitroglycerin Approved, Investigational Phase 4,Phase 3 55-63-0 4510
44
Verapamil Approved Phase 4 52-53-9 2520
45
Cilostazol Approved, Investigational Phase 4 73963-72-1 2754
46
Irbesartan Approved, Investigational Phase 4 138402-11-6 3749
47
Antipyrine Approved, Investigational Phase 4 60-80-0 2206
48
Aminophylline Approved Phase 4 317-34-0 9433
49
Ezetimibe Approved Phase 4 163222-33-1 150311
50
Insulin Lispro Approved Phase 4,Not Applicable 133107-64-9

Interventional clinical trials:

(show top 50) (show all 1219)
# Name Status NCT ID Phase Drugs
1 Efficacy of Thrombosuction in Primary Percutaneous Coronary Intervention of Acute Myocardial Infarction Unknown status NCT01156662 Phase 4
2 Pravastatin for Acute Myocardial Infarction With Minimally to Mildly Increased Levels of Serum Cholesterol Study Unknown status NCT00688922 Phase 4 Pravastatin
3 Sirolimus Eluting Stenting in Acute Myocardial Infarction Unknown status NCT00288210 Phase 4
4 Anti-Restenosis After AMI by Erythropoietin Unknown status NCT00423020 Phase 4 Erythropoietin
5 IRIS : Use of Implantable Defibrillator in High-Risk Patients Early After Acute Myocardial Infarction Unknown status NCT00157768 Phase 4
6 Microvascular Reperfusion Utilizing Sonothrombolysis in Acute Myocardial Infarction (MRUSMI TRIAL) Unknown status NCT02170103 Phase 4 Microbubbles
7 Comparison of Primary PCI vs. Post-thrombolysis PCI as Reperfusion Strategies in STEMI Unknown status NCT02268669 Phase 4
8 Treating Acute MI Patients With Aggrastat on Their Way to Hospital Unknown status NCT00300833 Phase 4 Tirofiban
9 N-3 Fatty Acids for the Prevention of Atrial Fibrillation in Patients With Acute Heart Failure Unknown status NCT00692718 Phase 4 Epadel, Eicosapentaenoic acid
10 Post-MI PET Scan Imaging of Inflammation Unknown status NCT02281305 Phase 4 Colchicine
11 Colchicine in ST-elevation Myocardial Infarction Unknown status NCT01936285 Phase 4 Colchicine 2 mg loading dose; 0.5 mg bid for 5 days;Placebo
12 Dissecting the Role of Distal Embolization of Athero-thrombotic Material in Primary PCI: the ThrombOticBurden and mIcrovAscularobStruction (TOBIAS) Study. Unknown status NCT01914055 Phase 4
13 Multicentre 2x2 Factorial Randomised Study Comparing Tirofiban Versus Abciximab and SES Versus BMS in AMI Unknown status NCT00229515 Phase 4
14 P3AMI Antiplatelet Trial Unknown status NCT02376283 Phase 4 Prasugrel;Clopidogrel;ticagrelor
15 Impact of Ticagrelor on the Endothelial Healing Following Drug-eluting Stent Implantation in the Patients With Acute Coronary Syndrome Unknown status NCT02037412 Phase 4 Ticagrelor;Clopidogrel
16 The Effect of Tongguan Capsule for MicroRNA Profiles in Coronary Heart Disease Patients Unknown status NCT02850627 Phase 4 Tongguan capsule;placebo capsule
17 Vitamin D and Inflammatory Cytokine Levels After Acute Myocardial Infraction (MI) Unknown status NCT01115842 Phase 4 Vitamin D
18 Effect of Nicorandil for the Patients of Acute ST Segment Elevation Myocardial Infarction Unknown status NCT02435797 Phase 4 Nicorandil;normal saline
19 Efficacy and Safety of BiomatrixTM Stent and 5mg-Maintenance Dose of Prasugrel in Patients With Acute Coronary Syndrome Unknown status NCT02446730 Phase 4 Prasugel;Clopidogrel
20 Efficacy Study of Combined Prasugrel and Bivalirudin Versus Clopidogrel and Heparin in Myocardial Infarction Unknown status NCT00976092 Phase 4 Prasugrel;Bivalirudin;Clopidogrel;Heparin
21 Thrombus Aspiration for OcLuded Coronary Artery Enhanced With Distal Injection Of Abciximab Unknown status NCT01383785 Phase 4
22 Desflurane-induced Myocardial Protection Unknown status NCT02019797 Phase 4 Desflurane
23 Ticagrelor and Clopidogrel on Reperfusion in Patients With AMI Unknown status NCT02233790 Phase 4 Ticagrelor;Clopidogrel
24 Can Insulin Glargine Improve Myocardial Function in Patients With T2D and Coronary Artery Disease (CAD) Unknown status NCT01035528 Phase 4 insulin glargine;metformin
25 Ticagrelor Versus Clopidogrel in Myocardial Salvage in Patients With STEMI Undergoing Primary PCI Unknown status NCT02792712 Phase 4 Ticagrelor;Clopidogrel
26 CT Coronary Angiogram Versus Traditional Care in Emergency Department Assessment of Potential ACS Unknown status NCT00933400 Phase 4
27 Multifactorial Intervention in Type 2 Diabetes - Italy Unknown status NCT01240070 Phase 4
28 Xience/Promus for Long Coronary Lesion Registry Unknown status NCT01147237 Phase 4
29 Omeprazole and Pantoprazole Antiplatelet Effect of Clopidogrel Clinical Trials(OPEN) Unknown status NCT01735227 Phase 4 omeprazole;Pantoprazole
30 A Morbidity-Mortality and Remodeling Study With Valsartan Unknown status NCT00133328 Phase 4 valsartan
31 The Pacing vs No Pacing Study - PNP Study Unknown status NCT02498639 Phase 4
32 The Application of Ticagrelor Combined With Low Molecular Weight Heparin During PCI Unknown status NCT02658838 Phase 4 Ticagrelor;full amount low molecular weight heparin;half amount low molecular weight heparin;No low molecular weight heparin
33 Bezafibrate for Hyperfibrinogenemia in Acute Myocardial Infarction Completed NCT02291796 Phase 4 Bezafibrate
34 Effect of Complementary Intracoronary Streptokinase Administration Immediately After Primary Percutaneous Coronary Intervention on Microvascular Perfusion and Late Term Infarct Size in Patients With Acute Myocardial Infarction Completed NCT00302419 Phase 4 intracoronary infusion,
35 GPIIbIIIa Inhibitors in the RESCUe and RESURCOR Networks at the Acute Myocardial Infarction Completed NCT00538317 Phase 4 tirofiban;tirofiban
36 REsistance to Aspirin and Clopidogrel in acuTe Myocardial Infarction Completed NCT01381185 Phase 4 Aspirin 200mg qd, Clopidogrel 2x75mg qd
37 Tight Glycemic Control Increases Cardiac Stem Cells During Acute Myocardial Infarction Completed NCT00863629 Phase 4 Insulin
38 The Effect of Erythropoietin at the Time of Reperfusion in Acute Myocardial Infarction Completed NCT00882466 Phase 4 human recombinant erythropoietin
39 BivaliRudin in Acute Myocardial Infarction vs Glycoprotein IIb/IIIa and Heparin :a Randomised Controlled Trial. Completed NCT01696110 Phase 4 Bivalirudin;heparin;heparin plus tirofiban
40 Southwest German Interventional Study in Acute Myocardial Infarction III Completed NCT01124890 Phase 4
41 Effects of Different Vasodilators on Coronary No-reflow During primAry percuTaneous Coronary intErvention in Patients With Acute Myocardial Infarction Completed NCT00712894 Phase 4 Diltiazem;Verapamil;Nitroglycerin
42 Safety and Efficacy of Three Different Loading Doses of Clopidogrel, in Patients With Acute Myocardial Infarction Completed NCT00882739 Phase 4 Clopidogrel 300 mg;Clopidogrel 600 mg;Clopidogrel 900 mg
43 Effect of Adjunctive Intracoronary Streptokinase on Late Term Left Ventricular Infarct Size and Volumes in Patients With Acute Myocardial Infarction Completed NCT00627809 Phase 4 Streptokinase
44 Effects of Atorvastatin 10 mg Versus 40 mg in Eight Months Follow-up Coronary Flow Reserve and Bone Marrow Stem Cell Mobilization in Patients With Acute Myocardial Infarction Completed NCT00536887 Phase 4 atorvastatin
45 Comparison Between Iso-Osmolar and Ipo-Osmolar Contrast Agents in Patients With Acute Myocardial Infarction (AMI) Undergoing Primary Percutaneous Coronary Intervention (PCI) Completed NCT00827788 Phase 4 Iodixanol;Iopromide
46 Comparison of Prasugrel and Ticagrelor in the Treatment of Acute Myocardial Infarction Completed NCT02808767 Phase 4 Prasugrel;Ticagrelor
47 The Effects of Facilitated Percutaeous Coronary Intervention in Acute Myocardial Infarction Completed NCT00611169 Phase 4 tirofiban
48 Intensive Insulin Therapy in Non-diabetic Patients With Acute Myocardial Infarction and Hyperglycaemia Completed NCT00362778 Phase 4 Insulin
49 Adjunctive Cilostazol Versus High Maintenance-dose ClopidogrEL in Acute Myocardial Infarction (AMI) Patients According to CYP2C19 Polymorphism Completed NCT00915733 Phase 4 cilostazol;clopidogrel (Plavix);aspirin (Acetylsalicylic acid)
50 Efficacy of Everolimus-Eluting Versus Zotarolimus-Eluting Sten for Coronary Lesions in Acute Myocardial Infarction Completed NCT01347554 Phase 4

Search NIH Clinical Center for Acute Myocardial Infarction

Genetic Tests for Acute Myocardial Infarction

Anatomical Context for Acute Myocardial Infarction

MalaCards organs/tissues related to Acute Myocardial Infarction:

41
Heart, Bone, Bone Marrow, Endothelial, Kidney, Brain, Testes

Publications for Acute Myocardial Infarction

Articles related to Acute Myocardial Infarction:

(show top 50) (show all 3004)
# Title Authors Year
1
MicroRNAs in pathophysiology of acute myocardial infarction and cardiogenic shock. ( 29947233 )
2018
2
rLj-RGD3, a novel recombinant toxin protein from Lampetra japonica, prevents coronary thrombosis-induced acute myocardial infarction by inhibiting platelet functions in rats. ( 29407168 )
2018
3
Circulating miR-379 as a potential novel biomarker for diagnosis of acute myocardial infarction. ( 29424915 )
2018
4
Meta-Analysis of Cell Therapy Studies in Heart Failure and Acute Myocardial Infarction. ( 29976694 )
2018
5
Toll-Like Receptors 2 and 4 Predict New-Onset Atrial Fibrillation in Acute Myocardial Infarction Patients. ( 29375116 )
2018
6
Acute Myocardial Infarction in a Patient with Isolated Dextrocardia. ( 29431312 )
2018
7
Acute myocardial infarction after blunt chest wall trauma with underlying coronary aneurysm: a case report. ( 29914384 )
2018
8
Chart validation of inpatient ICD-9-CM administrative diagnosis codes for acute myocardial infarction (AMI) among intravenous immune globulin (IGIV) users in the Sentinel Distributed Database. ( 29446185 )
2018
9
Impact of generalized anxiety disorder (GAD) on prehospital delay of acute myocardial infarction patients. Findings from the multicenter MEDEA study. ( 29383439 )
2018
10
Ac-SDKP decreases mortality and cardiac rupture after acute myocardial infarction. ( 29364896 )
2018
11
Atrioventricular block after acute myocardial infarction and its association with other clinical parameters in Pakistani patients: an institutional perspective. ( 29784020 )
2018
12
Effects of smoke-free air law on acute myocardial infarction hospitalization in Indianapolis and Marion County, Indiana. ( 29426315 )
2018
13
Hospital mortality and thirty day readmission among patients with non-acute myocardial infarction related cardiogenic shock. ( 29929933 )
2018
14
Revascularization strategies in cardiogenic shock complicating acute myocardial infarction: A systematic review and meta-analysis. ( 29909948 )
2018
15
Outcome after revascularisation of acute myocardial infarction with cardiogenic shock on extracorporeal life support. ( 29400656 )
2018
16
Functional genetic variants in the SIRT5 gene promoter in acute myocardial infarction. ( 29981421 )
2018
17
Cardiac rupture during acute myocardial infarction diagnosed clinically. ( 29394186 )
2018
18
Accelerated idioventricular rhythm degenerating into bidirectional ventricular tachycardia following acute myocardial infarction. ( 29429799 )
2018
19
Blood cardioplegia for cardiac surgery in acute myocardial infarction: rat experiments with two widely used solutions. ( 29452370 )
2018
20
Buckberg's blood cardioplegia for protection of adult and senile myocardium in a rat in vitro model of acute myocardial infarction. ( 29432894 )
2018
21
Cytomegalovirus infection in a patient with systemic lupus erythematosus and acute myocardial infarction - cause or causal relationship? ( 29915649 )
2018
22
Efficacy and Safety of Cyclosporine in Acute Myocardial Infarction: A Systematic Review and Meta-Analysis. ( 29970999 )
2018
23
Idiopathic Sudden Sensorineural Hearing Loss Is Not a Sentinel Event for Acute Myocardial Infarction. ( 29912831 )
2018
24
A foreign older diabetic woman with an acute myocardial infarction: when cognitive biases in clinical decision-making become especially important. ( 29437739 )
2018
25
Clinical characteristics and value in early reperfusion therapy for new onset right bundle branch block in patients with acute myocardial infarction. ( 29467855 )
2018
26
Clinical Significance of Newly Diagnosed Diabetes Mellitus in the Era of DES for Acute Myocardial Infarction. ( 29441749 )
2018
27
Effects of Short-term High Dose Atorvastatin on Left Ventricular Remodeling in Patients with First Time Attack of Anterior Acute Myocardial Infarction. ( 29976277 )
2018
28
Gambogic acid exerts cardioprotective effects in a rat model of acute myocardial infarction through inhibition of inflammation, iNOS and NF-I_B/p38 pathway. ( 29434760 )
2018
29
Acute stress disorder and C-reactive protein in patients with acute myocardial infarction. ( 29488809 )
2018
30
Prognostic value of new-onset right bundle-branch block in acute myocardial infarction patients: a systematic review and meta-analysis. ( 29576967 )
2018
31
Folic Acid-Derived Hydrogel Enhances the Survival and Promotes Therapeutic Efficacy of iPS Cells for Acute Myocardial Infarction. ( 29974744 )
2018
32
MicroRNAs in acute myocardial infarction: Evident value as novel biomarkers? ( 29424735 )
2018
33
2017 ESC guidelines for the management of acute myocardial infarction in patients presenting with ST-segment elevation: comments from the Dutch ACS working group. ( 29974355 )
2018
34
Rapid increases in nitrogen oxides are associated with acute myocardial infarction: A case-crossover study. ( 29446990 )
2018
35
Acute myocardial infarction in a 25-year-old woman with sitosterolemia. ( 29174072 )
2018
36
Persistent Inflammation, Stem Cell-Induced Systemic Anti-Inflammatory Effects, and Need for Repeated Stem Cell Injections: Critical Concepts Influencing Optimal Stem Cell Strategies for Treating Acute Myocardial Infarction and Heart Failure. ( 29440037 )
2018
37
Fried food intake and risk of nonfatal acute myocardial infarction in the Costa Rica Heart Study. ( 29447246 )
2018
38
Recurrent Acute Myocardial Infarction Caused by Intra-cardiac Metastatic Undifferentiated Pleomorphic Sarcoma during Cancer Treatment. ( 29629023 )
2018
39
Long-Term Prognostic Implications of Previous Silent Myocardial Infarction in Patients Presenting With Acute Myocardial Infarction. ( 29680352 )
2018
40
A Preliminary Study of microRNA-208b after Acute Myocardial Infarction: Impact on 6-Month Survival. ( 29977411 )
2018
41
Effects of low dose of aliskiren on isoproterenol-induced acute myocardial infarction in rats. ( 29975120 )
2018
42
Gene expression pattern of TCR repertoire and alteration expression of IL-17A gene of I^I' T cells in patients with acute myocardial infarction. ( 29976209 )
2018
43
Revision: prognostic impact of baseline glucose levels in acute myocardial infarction complicated by cardiogenic shock-a substudy of the IABP-SHOCK II-trial. ( 29423774 )
2018
44
Correction to: Air quality and acute myocardial infarction in adults during the 2016 Hangzhou G20 summit. ( 29450769 )
2018
45
Acute myocardial infarction in a patient with a recent diagnosis of Crohn's disease. ( 29954623 )
2018
46
Effect of a Quality Improvement Intervention on Clinical Outcomes in Patients in India With Acute Myocardial Infarction: The ACS QUIK Randomized Clinical Trial. ( 29450524 )
2018
47
Quality of Care and 30-day Mortality of Women and Men With Acute Myocardial Infarction. ( 29980406 )
2018
48
Hospital quality reporting and improvement in quality of care for patients with acute myocardial infarction. ( 29973281 )
2018
49
Hyperuricemia is associated with short-term outcomes in elderly patients with acute myocardial infarction. ( 29411328 )
2018
50
Long-term Prognosis and Clinical Characteristics of Patients with Newly Diagnosed Diabetes Mellitus Detected after First Acute Myocardial Infarction: from KAMIR-NIH Registry. ( 29441746 )
2018

Variations for Acute Myocardial Infarction

Copy number variations for Acute Myocardial Infarction from CNVD:

7
# CNVD ID Chromosom Start End Type Gene Symbol CNVD Disease
1 210497 6 30400000 36600000 Amplification C4B Acute myocardial infarction

Expression for Acute Myocardial Infarction

LifeMap Discovery
Genes differentially expressed in tissues of Acute Myocardial Infarction patients vs. healthy controls: 35
# Gene Description Tissue Up/Dn Fold Change (log2) P value
1 EGR3 early growth response 3 Blood + 5.52 0.000
2 LOC286058 uncharacterized LOC286058 Blood + 4.73 0.000
3 CXCL8 chemokine (C-X-C motif) ligand 8 Blood + 3.51 0.004
4 LEP leptin Heart + 3.45 0.011
5 ID1 inhibitor of DNA binding 1, dominant negative helix-loop-helix protein Blood + 3.18 0.007
Search GEO for disease gene expression data for Acute Myocardial Infarction.

Pathways for Acute Myocardial Infarction

Pathways related to Acute Myocardial Infarction according to GeneCards Suite gene sharing:

# Super pathways Score Top Affiliating Genes
1
Show member pathways
11.16 ACE ADRB1 TNNI3 TNNT2
2 10.32 ACE PLAT

GO Terms for Acute Myocardial Infarction

Cellular components related to Acute Myocardial Infarction according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 troponin complex GO:0005861 9.16 TNNI3 TNNT2
2 cardiac myofibril GO:0097512 8.96 TNNI3 TNNT2
3 cardiac Troponin complex GO:1990584 8.62 TNNI3 TNNT2

Biological processes related to Acute Myocardial Infarction according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 positive regulation of vascular endothelial cell proliferation GO:1905564 9.37 MIR29A MIR499A
2 regulation of muscle contraction GO:0006937 9.32 TNNI3 TNNT2
3 regulation of blood vessel diameter GO:0097746 9.26 ACE NPPB
4 heart contraction GO:0060047 9.16 ACE TNNI3
5 negative regulation of ATPase activity GO:0032780 8.96 TNNI3 TNNT2
6 transition between fast and slow fiber GO:0014883 8.62 MIR208B MIR499A

Molecular functions related to Acute Myocardial Infarction according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 troponin C binding GO:0030172 8.62 TNNI3 TNNT2

Sources for Acute Myocardial Infarction

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
17 ExPASy
19 FMA
28 GO
29 GTR
30 HGMD
31 HMDB
32 HPO
33 ICD10
34 ICD10 via Orphanet
35 ICD9CM
36 IUPHAR
37 KEGG
38 LifeMap
40 LOVD
42 MedGen
44 MeSH
45 MESH via Orphanet
46 MGI
49 NCI
50 NCIt
51 NDF-RT
54 NINDS
55 Novoseek
57 OMIM
58 OMIM via Orphanet
62 PubMed
64 QIAGEN
69 SNOMED-CT via HPO
70 SNOMED-CT via Orphanet
71 TGDB
72 Tocris
73 UMLS
74 UMLS via Orphanet
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