MCID: ACT077
MIFTS: 16

Acute Orbital Inflammation

Categories: Eye diseases

Aliases & Classifications for Acute Orbital Inflammation

MalaCards integrated aliases for Acute Orbital Inflammation:

Name: Acute Orbital Inflammation 12 15
Acute Inflammation of Orbit 12

Classifications:



External Ids:

Disease Ontology 12 DOID:11230
ICD9CM 36 376.0 376.00
SNOMED-CT 69 20551005
ICD10 34 H05.0 H05.00
UMLS 74 C0155256

Summaries for Acute Orbital Inflammation

MalaCards based summary : Acute Orbital Inflammation, also known as acute inflammation of orbit, is related to orbital cellulitis and orbital periostitis. An important gene associated with Acute Orbital Inflammation is RHNO1 (RAD9-HUS1-RAD1 Interacting Nuclear Orphan 1). Affiliated tissues include eye, and related phenotypes are Decreased shRNA abundance (Z-score < -2) and Decreased shRNA abundance (Z-score < -2)

Related Diseases for Acute Orbital Inflammation

Diseases in the Acute Orbital Inflammation family:

Chronic Orbital Inflammation

Diseases related to Acute Orbital Inflammation via text searches within MalaCards or GeneCards Suite gene sharing:

(show all 17)
# Related Disease Score Top Affiliating Genes
1 orbital cellulitis 30.1 BIN1 CRP NT5C2 PGBD1 RHNO1
2 orbital periostitis 11.2
3 orbital osteomyelitis 11.2
4 orbital tenonitis 11.2
5 intracranial sinus thrombosis 10.0 PGBD1 RHNO1
6 cavernous sinus thrombosis 10.0 PGBD1 RHNO1
7 mastoiditis 9.9 CRP RHNO1
8 dental abscess 9.9 BIN1 CRP
9 intracranial abscess 9.8 BIN1 CRP
10 pleural empyema 9.8 CRP PGBD1
11 herpes zoster 9.8
12 herpes zoster ophthalmicus 9.8
13 ethmoid sinusitis 9.8 CRP RHNO1
14 acute cholangitis 9.7 CRP NT5C2
15 orbital disease 9.7 CRP PGBD1 RHNO1
16 subdural empyema 9.6 CRP PGBD1
17 sphenoid sinusitis 9.5 CRP NT5C2 RHNO1

Graphical network of the top 20 diseases related to Acute Orbital Inflammation:



Diseases related to Acute Orbital Inflammation

Symptoms & Phenotypes for Acute Orbital Inflammation

GenomeRNAi Phenotypes related to Acute Orbital Inflammation according to GeneCards Suite gene sharing:

27
# Description GenomeRNAi Source Accession Score Top Affiliating Genes
1 Decreased shRNA abundance (Z-score < -2) GR00366-A-148 9.1 CRP
2 Decreased shRNA abundance (Z-score < -2) GR00366-A-17 9.1 NT5C2
3 Decreased shRNA abundance (Z-score < -2) GR00366-A-180 9.1 CRP
4 Decreased shRNA abundance (Z-score < -2) GR00366-A-68 9.1 CRP
5 Decreased shRNA abundance (Z-score < -2) GR00366-A-89 9.1 CRP NT5C2

Drugs & Therapeutics for Acute Orbital Inflammation

Search Clinical Trials , NIH Clinical Center for Acute Orbital Inflammation

Genetic Tests for Acute Orbital Inflammation

Anatomical Context for Acute Orbital Inflammation

MalaCards organs/tissues related to Acute Orbital Inflammation:

42
Eye

Publications for Acute Orbital Inflammation

Articles related to Acute Orbital Inflammation:

# Title Authors Year
1
Case Series: Herpes Zoster Ophthalmicus with Acute Orbital Inflammation. ( 29554007 )
2018

Variations for Acute Orbital Inflammation

Expression for Acute Orbital Inflammation

Search GEO for disease gene expression data for Acute Orbital Inflammation.

Pathways for Acute Orbital Inflammation

GO Terms for Acute Orbital Inflammation

Molecular functions related to Acute Orbital Inflammation according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 identical protein binding GO:0042802 8.8 BIN1 CRP PGBD1

Sources for Acute Orbital Inflammation

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
17 EFO
18 ExPASy
20 FMA
29 GO
30 GTR
31 HGMD
32 HMDB
33 HPO
34 ICD10
35 ICD10 via Orphanet
36 ICD9CM
37 IUPHAR
38 KEGG
39 LifeMap
41 LOVD
43 MedGen
45 MeSH
46 MESH via Orphanet
47 MGI
50 NCI
51 NCIt
52 NDF-RT
55 NINDS
56 Novoseek
58 OMIM
59 OMIM via Orphanet
63 PubMed
65 QIAGEN
70 SNOMED-CT via HPO
71 SNOMED-CT via Orphanet
72 TGDB
73 Tocris
74 UMLS
75 UMLS via Orphanet
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