MCID: ACT027
MIFTS: 61

Acute Pancreatitis

Categories: Bone diseases, Endocrine diseases, Gastrointestinal diseases, Genetic diseases, Immune diseases, Rare diseases

Aliases & Classifications for Acute Pancreatitis

MalaCards integrated aliases for Acute Pancreatitis:

Name: Acute Pancreatitis 12 76 37 29 55 6 15 63 73
Pancreatitis, Acute Necrotizing 73
Acute Necrotizing Pancreatitis 12
Pancreatitis Necrotizing 12
Necrotizing Pancreatitis 55

Classifications:



External Ids:

Disease Ontology 12 DOID:2913
ICD10 33 K85 K85.9
ICD9CM 35 577.0
NCIt 50 C95437
SNOMED-CT 68 39726008
KEGG 37 H01681

Summaries for Acute Pancreatitis

PubMed Health : 63 About acute pancreatitis: Acute pancreatitis is an inflammation of the pancreas that typically causes very sudden and very severe stomach ache. The most common causes are gallstones and excessive alcohol consumption.Acute pancreatitis can have serious complications, so it is typically treated in the hospital. Most of the time it passes without any serious problems developing in about one to two weeks. But in more severe cases of pancreatitis, treating the complications may take up to several months. Complications of pancreatitis can be fatal.

MalaCards based summary : Acute Pancreatitis, also known as pancreatitis, acute necrotizing, is related to recurrent acute pancreatitis and pancreatitis. An important gene associated with Acute Pancreatitis is CRP (C-Reactive Protein), and among its related pathways/superpathways are Innate Immune System and Transcriptional misregulation in cancer. The drugs Nefopam and Tramadol have been mentioned in the context of this disorder. Affiliated tissues include pancreas, lung and liver, and related phenotypes are Increased shRNA abundance (Z-score > 2) and Increased shRNA abundance (Z-score > 2)

Wikipedia : 76 Acute pancreatitis is a sudden inflammation of the pancreas. Causes in order of frequency include a... more...

Related Diseases for Acute Pancreatitis

Diseases in the Pancreatitis family:

Pancreatitis, Hereditary Autoimmune Pancreatitis
Acute Pancreatitis Prss1-Related Hereditary Pancreatitis
Autoimmune Pancreatitis Type 2 Autoimmune Pancreatitis Type 1
Recurrent Acute Pancreatitis

Diseases related to Acute Pancreatitis via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50) (show all 560)
# Related Disease Score Top Affiliating Genes
1 recurrent acute pancreatitis 33.8 LPL SCT SPINK1
2 pancreatitis 31.6 CCK CPB1 CRP CTSB LPL PLA2G2A
3 obstructive jaundice 30.6 CRP CXCL8 IL6
4 gastroenteritis 30.3 CRP CXCL8 IL10 IL6
5 colitis 30.3 CXCL8 IL10 IL6 MPO
6 dengue hemorrhagic fever 30.2 CXCL8 IL10 IL6
7 hemorrhagic fever with renal syndrome 30.2 CRP CXCL8 IL6
8 arthritis 30.1 CXCL8 IL10 IL18 IL6
9 acute cholangitis 30.1 CRP IL6
10 ulcerative colitis 30.1 CRP CXCL8 IL10 IL6 MPO
11 necrotizing fasciitis 30.0 CXCL8 IL18 IL6
12 fasciitis 30.0 CXCL8 IL18 IL6
13 systemic lupus erythematosus 30.0 CRP CXCL8 ELANE IL10 IL18 IL6
14 aortic aneurysm, familial abdominal, 1 30.0 CRP ELANE IL6
15 leptospirosis 30.0 CRP CXCL8 IL10 IL6
16 meningitis 30.0 CRP CXCL8 IL10 IL6
17 polyarteritis nodosa 29.9 CRP IL6 MPO
18 acalculous cholecystitis 29.9 CCK CRP
19 peptic ulcer disease 29.9 CXCL8 IL10 SCT
20 cystic fibrosis 29.9 CXCL8 ELANE MPO REG3A SCT SPINK1
21 diabetes mellitus, noninsulin-dependent 29.9 CRP IL18 IL6 LPL SST
22 peritonitis 29.9 CRP CXCL8 IL10 IL6 MPO
23 malaria 29.9 CRP CXCL8 IL10 IL18 IL6
24 duodenal ulcer 29.9 CCK CXCL8 SCT SST
25 morbid obesity 29.8 CCK CRP LPL
26 rheumatoid arthritis 29.8 CRP CXCL8 IL10 IL18 IL6 PLA2G2A
27 microscopic polyangiitis 29.8 IL10 MPO
28 streptococcal toxic-shock syndrome 29.7 CXCL8 IL6
29 brucellosis 29.7 CRP CXCL8 IL10 IL18 IL6
30 paralytic ileus 29.7 CCK CRP
31 alcoholic hepatitis 29.7 CXCL8 IL10 IL6
32 sleep apnea 29.7 CRP CXCL8 IL6
33 toxic shock syndrome 29.7 CXCL8 IL10 IL6
34 acute respiratory distress syndrome 29.7 CXCL8 ELANE IL6
35 mouth disease 29.7 CRP IL10 IL6
36 juvenile rheumatoid arthritis 29.6 CRP IL18 IL6
37 pyelonephritis 29.6 CRP CXCL8 IL10 IL6
38 pancreatic agenesis 1 29.6 PNLIP SCT SPINK1
39 gallbladder disease 29.6 CCK IL10 SST
40 adult respiratory distress syndrome 29.6 CXCL8 ELANE IL10 IL6
41 bacterial infectious disease 29.6 CRP CXCL8 ELANE IL10 IL18 IL6
42 respiratory failure 29.6 CRP CXCL8 ELANE
43 vasculitis 29.6 CRP ELANE MPO
44 appendicitis 29.5 CRP CXCL8 IL10 IL6 MPO
45 biliary dyskinesia 29.5 CCK SCT
46 inflammatory bowel disease 29.4 CRP CXCL8 ELANE IL10 IL18 IL6
47 alcoholic pancreatitis 29.4 CCK LPL SCT SPINK1
48 pneumonia 29.4 CRP CXCL8 ELANE IL10 IL6 MPO
49 exocrine pancreatic insufficiency 29.2 CCK PNLIP SCT SPINK1
50 body mass index quantitative trait locus 11 29.1 CCK CRP IL18 IL6 LPL PNLIP

Comorbidity relations with Acute Pancreatitis via Phenotypic Disease Network (PDN): (show all 39)


Active Peptic Ulcer Disease Acute Cystitis
Acute Kidney Failure Acute Vascular Insufficiency of Intestine
Alcohol Abuse Alcoholic Gastritis
Alcoholic Hepatitis Alcoholic Liver Cirrhosis
Atrophic Gastritis Biliary Tract Disease
Biliary Tract Neoplasm Cholangitis
Cholecystitis Cholestasis
Chronic Kidney Failure Chronic Myocardial Ischemia
Deficiency Anemia Duodenitis
Esophageal Disease Esophagitis
Gallbladder Disease Heart Disease
Hepatitis Hyperlipoproteinemia, Type Iv
Hypertension, Essential Hypothyroidism
Intestinal Obstruction Iron Deficiency Anemia
Irritable Bowel Syndrome Ischemic Heart Disease
Liver Disease Pancreatic Agenesis 1
Pancreatic Cancer Pancreatitis, Hereditary
Paralytic Ileus Postcholecystectomy Syndrome
Protein-Energy Malnutrition Respiratory Failure
Strawberry Gallbladder

Graphical network of the top 20 diseases related to Acute Pancreatitis:



Diseases related to Acute Pancreatitis

Symptoms & Phenotypes for Acute Pancreatitis

GenomeRNAi Phenotypes related to Acute Pancreatitis according to GeneCards Suite gene sharing:

26 (show all 25)
# Description GenomeRNAi Source Accession Score Top Affiliating Genes
1 Increased shRNA abundance (Z-score > 2) GR00366-A-100 9.78 MPO
2 Increased shRNA abundance (Z-score > 2) GR00366-A-113 9.78 CPB1
3 Increased shRNA abundance (Z-score > 2) GR00366-A-114 9.78 PLA2G6
4 Increased shRNA abundance (Z-score > 2) GR00366-A-125 9.78 SPINK1
5 Increased shRNA abundance (Z-score > 2) GR00366-A-126 9.78 MPO
6 Increased shRNA abundance (Z-score > 2) GR00366-A-131 9.78 SPINK1
7 Increased shRNA abundance (Z-score > 2) GR00366-A-157 9.78 MPO
8 Increased shRNA abundance (Z-score > 2) GR00366-A-16 9.78 CPB1
9 Increased shRNA abundance (Z-score > 2) GR00366-A-161 9.78 PLA2G6
10 Increased shRNA abundance (Z-score > 2) GR00366-A-176 9.78 MPO
11 Increased shRNA abundance (Z-score > 2) GR00366-A-186 9.78 MPO
12 Increased shRNA abundance (Z-score > 2) GR00366-A-194 9.78 PLA2G6
13 Increased shRNA abundance (Z-score > 2) GR00366-A-2 9.78 SPINK1
14 Increased shRNA abundance (Z-score > 2) GR00366-A-29 9.78 CPB1 MPO PLA2G6 SPINK1
15 Increased shRNA abundance (Z-score > 2) GR00366-A-3 9.78 CPB1
16 Increased shRNA abundance (Z-score > 2) GR00366-A-32 9.78 CPB1
17 Increased shRNA abundance (Z-score > 2) GR00366-A-36 9.78 MPO
18 Increased shRNA abundance (Z-score > 2) GR00366-A-49 9.78 CPB1
19 Increased shRNA abundance (Z-score > 2) GR00366-A-57 9.78 MPO
20 Increased shRNA abundance (Z-score > 2) GR00366-A-63 9.78 PLA2G6
21 Increased shRNA abundance (Z-score > 2) GR00366-A-67 9.78 SPINK1
22 Increased shRNA abundance (Z-score > 2) GR00366-A-7 9.78 MPO
23 Increased shRNA abundance (Z-score > 2) GR00366-A-70 9.78 MPO
24 Increased shRNA abundance (Z-score > 2) GR00366-A-73 9.78 CPB1 PLA2G6
25 Increased shRNA abundance (Z-score > 2) GR00366-A-85 9.78 CPB1

MGI Mouse Phenotypes related to Acute Pancreatitis:

46
# Description MGI Source Accession Score Top Affiliating Genes
1 homeostasis/metabolism MP:0005376 9.83 CCK CRP CTSB ELANE IL10 IL18
2 digestive/alimentary MP:0005381 9.7 CTSB IL10 IL18 IL6 PNLIP SPINK1
3 immune system MP:0005387 9.36 CRP CTSB ELANE IL10 IL18 IL6

Drugs & Therapeutics for Acute Pancreatitis

PubMedHealth treatment related to Acute Pancreatitis: 63

No treatment is available for dealing with the root cause of pancreatitis. But there are a number of options for reducing strain on the pancreas and relieving symptoms. Because fluid levels can drop due to acute pancreatitis, the first step is to prevent dehydration by using infusion therapy. A hollow needle inserted in an arm vein is used to release a solution into the bloodstream. Medication is used to provide relief from pain, nausea and vomiting. Stronger painkillers such as opioids are sometimes needed, and they may make you feel drowsy or light-headed.Solid foods are avoided until the pain recedes and appetite returns to give the pancreas a chance to recuperate. In mild cases of pancreatitis it is sometimes possible to return to eating solid foods after just a few days. If the symptoms last longer, artificial feeding may be necessary to supply your body with enough nutrients.If the pancreatitis is caused by gallstones, the stones may need to be removed using endoscopic retrograde cholangiography. After treatment the gallbladder is surgically removed to prevent further episodes.

Drugs for Acute Pancreatitis (from DrugBank, HMDB, Dgidb, PharmGKB, IUPHAR, NovoSeek, BitterDB):

(show top 50) (show all 252)
# Name Status Phase Clinical Trials Cas Number PubChem Id
1 Nefopam Approved, Investigational Phase 4 13669-70-0
2
Tramadol Approved, Investigational Phase 4,Phase 2,Phase 3 27203-92-5 33741
3
Ropivacaine Approved Phase 4,Phase 2,Phase 3,Phase 1 84057-95-4 175805 71273
4
Clonidine Approved Phase 4 4205-90-7 2803
5
Sufentanil Approved, Investigational Phase 4 56030-54-7 41693
6
Acetaminophen Approved Phase 4 103-90-2 1983
7
Chlorhexidine Approved, Vet_approved Phase 4 55-56-1 2713 9552079
8
Metronidazole Approved Phase 4 443-48-1 4173
9
Meropenem Approved, Investigational Phase 4,Phase 1,Phase 2 119478-56-7 64778 441130
10
Cefoperazone Approved, Investigational Phase 4 62893-19-0 44185
11
Somatostatin Approved, Investigational Phase 4,Phase 3,Not Applicable 51110-01-1, 38916-34-6 53481605
12
Epinephrine Approved, Vet_approved Phase 4,Not Applicable 51-43-4 5816
13
Racepinephrine Approved Phase 4,Not Applicable 329-65-7 838
14
Indomethacin Approved, Investigational Phase 4,Phase 3,Phase 2,Not Applicable 53-86-1 3715
15
Resveratrol Approved, Experimental, Investigational Phase 4 501-36-0 445154
16
Dexmedetomidine Approved, Vet_approved Phase 4 113775-47-6 68602 5311068
17
Ketorolac Approved Phase 4,Phase 2,Phase 3 66635-83-4, 74103-06-3 3826
18
Cilastatin Approved, Investigational Phase 4 82009-34-5 6435415 5280454
19
Imipenem Approved Phase 4 74431-23-5, 64221-86-9 104838
20
Protein C Approved Phase 4
21
Ursodeoxycholic acid Approved, Investigational Phase 4 128-13-2 31401
22
Atropine Approved, Vet_approved Phase 4 51-55-8, 5908-99-6 174174
23
Glycerol Approved, Investigational Phase 4,Phase 3 56-81-5 753
24
Zinc Approved, Investigational Phase 4,Phase 3 7440-66-6
25
Azathioprine Approved Phase 4 446-86-6 2265
26
Thioguanine Approved Phase 4 154-42-7 2723601
27
Serine Approved, Nutraceutical Phase 4,Phase 1 56-45-1 5951
28 Fat Emulsions, Intravenous Phase 4
29 Omega 3 Fatty Acid Phase 4,Phase 2
30 Soy Bean Phase 4
31 Olive Phase 4,Not Applicable
32 Soybean oil, phospholipid emulsion Phase 4
33 Parenteral Nutrition Solutions Phase 4
34 Pharmaceutical Solutions Phase 4,Phase 2,Phase 3,Phase 1,Not Applicable
35 Analgesics, Non-Narcotic Phase 4,Phase 3,Phase 2,Phase 1,Not Applicable
36 Central Nervous System Depressants Phase 4,Phase 2,Phase 3,Phase 1,Not Applicable
37 Adjuvants, Anesthesia Phase 4,Phase 2,Phase 3,Phase 1
38 Narcotics Phase 4,Phase 2,Phase 3,Phase 1
39 Peripheral Nervous System Agents Phase 4,Phase 2,Phase 3,Phase 1,Not Applicable
40 Anesthetics, Local Phase 4,Phase 2,Phase 3,Not Applicable
41 Anesthetics Phase 4,Phase 2,Phase 3,Phase 1,Not Applicable
42 Anesthetics, General Phase 4,Phase 2,Phase 3,Phase 1
43 Analgesics Phase 4,Phase 2,Phase 3,Phase 1,Not Applicable
44 Anesthetics, Intravenous Phase 4,Phase 2,Phase 3,Phase 1
45 Analgesics, Opioid Phase 4,Phase 2,Phase 3,Phase 1
46 Antipyretics Phase 4
47 Anti-Bacterial Agents Phase 4,Phase 2,Phase 3,Phase 1,Not Applicable
48 Antiparasitic Agents Phase 4
49 Antiprotozoal Agents Phase 4
50 Sulperazone Phase 4

Interventional clinical trials:

(show top 50) (show all 235)
# Name Status NCT ID Phase Drugs
1 Comparative Study About the Impact of Two Oil Emulsions Administered Intravenously on Severe Acute Pancreatitis Unknown status NCT01376817 Phase 4 Fat emulsion with MCT, LCT, olive oil and omega 3 fatty acids;Fat emulsion with MCT and LCT
2 Epidural Analgesia for Pancreatitis (Epipan Study) Unknown status NCT02126332 Phase 4
3 Multi-center Clinical Study of Early Antibios of Severe Acute Pancreatitis Unknown status NCT01992198 Phase 4 cefoperazone + metronidazole;Somatostatin;Meropenem
4 Epinephrine Sprayed on the Papilla for the Prevention of Post-ERCP Pancreatitis Unknown status NCT02839356 Phase 4 epinephrine;normal saline
5 Oral Resveratrol to Prevent Post-ERCP Pancreatitis Unknown status NCT02947932 Phase 4 Resveratrol;Indomethacin
6 Dexmedetomidine Hydrochloride in the Prevention of Organ Failure Following Severe Acute Pancreatitis Unknown status NCT02691598 Phase 4 Infusion
7 COX-2 Inhibitor to Prevent Post-ERCP Pancreatitis Unknown status NCT02964403 Phase 4 Cox-2;Indomethacin
8 Imipenem Prophylaxis in Patients With Acute Pancreatitis Completed NCT02897206 Phase 4 Imipenem;Placebo
9 Activated Protein C in Severe Acute Pancreatitis Completed NCT01017107 Phase 4 Activated protein C
10 Enteral Nutrition in Acute Pancreatitis Completed NCT01965873 Phase 4
11 The Correlations Between Early Enteral Nutrition and Intra-abdominal Pressure in Severe Acute Pancreatitis Completed NCT01507766 Phase 4 early enteral nutrition;Delayed enteral nutrition
12 Acute Pancreatitis and Acute Fluid Collections Completed NCT00786929 Phase 4 Conservative treatment
13 Early Enteral Nutrition for Severe Acute Pancreatitis Completed NCT00995098 Phase 4
14 Timing of Indomethacin Administration for the Prevention of Post-ERCP Pancreatitis (PEP) Completed NCT02111707 Phase 4 Rectal indomethacin 100mg one time before or after ERCP
15 A Trial of 0.025 Wire Guided Cannulation Versus Current Practice 0.035 Wire Guided Cannulation Completed NCT01408264 Phase 4
16 UDCA for Symptomatic Gallstone Disease Completed NCT00161083 Phase 4 ursodeoxycholic acid
17 Nutritional and Metabolic Evaluation of a Tube Feeding Immune Enhancing Diet in ICU Patients Completed NCT00560157 Phase 4
18 To Study the Effects of Lipid Emulsion on Hemodynamics in Organophosphate Compound Poisoning Completed NCT03564574 Phase 4
19 Effect of Early Nutritional Therapy on Frailty, Functional Outcomes and Recovery of Undernourished Medical Inpatients Trial Completed NCT02517476 Phase 4
20 Treatment of Acute Pancreatitis With Ketorolac Recruiting NCT02885441 Phase 4 Ketorolac;Placebo
21 Thiopurine Induced Pancreatitis in IBD Patients Recruiting NCT02281799 Phase 4 Azathioprine
22 Calcium Administration in Cardiac Surgery Recruiting NCT03772990 Phase 4 Calcium Chloride;0.9% Sodium Chloride
23 Rectal Indomethacin to Prevent Post ESWL-pancreatitis Recruiting NCT02797067 Phase 4 indomethacin suppository;Glycerin Suppository
24 Intensive Insulin for Severe/Moderate Hypertriglyceridemia Pancreatitis. Not yet recruiting NCT03501680 Phase 4 Insulin
25 Intravenous Administration of Insulin and Plasma Exchange on Triglyceride Levels in Early Stage of Hypertriglyceridemia-induced Pancreatitis Not yet recruiting NCT03342807 Phase 4 Insulin
26 Pancreatitis CytoSorbents (CytoSorb®) Inflammatory Cytokine Removal Not yet recruiting NCT03082469 Phase 4
27 Ulinastatin in Severe Acute Pancreatitis Suspended NCT01132521 Phase 4 ulinastatin;placebo
28 IHPOTOTAM : Induced HyPOthermia TO Treat Adult Meningitis Terminated NCT00774631 Phase 4
29 Epidural Anesthesia in Acute Pancreatitis Unknown status NCT02617199 Phase 2, Phase 3 Epidural anesthesia;intravenous analgesia
30 Fluid Resuscitation in Acute Pancreatitis Unknown status NCT02709044 Phase 2, Phase 3 Ringer lactate
31 Evaluation of Effect of Integrated Treatment by Traditional Chinese and Western Medicine for Severe Acute Pancreatitis Unknown status NCT00506337 Phase 2, Phase 3 Qingyi granules
32 Efficacy of Administration of Somatostatin in the Prevention of Post-endoscopic Retrograde Cholangiopancreatography (ERCP) Pancreatitis Unknown status NCT01060826 Phase 3 somatostatin, intravenous bolus;somatostatin
33 Effect of Traditional Chinese Medicine on GI Function Recovery and Nutrition Support in SAP Unknown status NCT00508729 Phase 2, Phase 3 Qingyi granules
34 Safety and Efficacy in LPL-Deficient Subjects of AMT-011, an Adeno-Associated Viral Vector Expressing Human Lipoprotein Lipase [S447X] Unknown status NCT01109498 Phase 2, Phase 3 Mycophenolate mofetil;cyclosporine
35 MIld to MOderate Acute Pancreatitis: Early naSogastric Tube Feeding Compared With pAncreas Rest (MIMOSA) Completed NCT01128478 Phase 2, Phase 3
36 Indomethacin Decreases Post-ERCP Pancreatitis Completed NCT02110810 Phase 3 Indomethacin;2.6-g suppository of glycerin
37 Pentoxifylline Treatment in Acute Pancreatitis (AP) Completed NCT02487225 Phase 3 Pentoxifylline;Placebo
38 Trial of Aggressive Hydration Versus Rectal Indomethacin for Prevention of Post-ERCP Pancreatitis Completed NCT03629600 Phase 2, Phase 3 Lactated Ringer;Rectal Form Indometacin
39 Use of Streptokinase for Enhancement of Percutaneous Drainage of Pancreatic Necrosis Completed NCT01977118 Phase 2, Phase 3 streptokinase
40 Lactated Ringers With or Without Rectal Indomethacin to Prevent Post-ERCP Pancreatitis Completed NCT02641561 Phase 3 Indomethacin;Lactated Ringer's Solution;Normal Saline;Placebo
41 Does Glyceryl Nitrate Prevent Post-Endoscopic Retrograde Cholangiopancreaticography (ERCP) Pancreatitis? Completed NCT00121901 Phase 3 glyceryl nitrate
42 Effects of Delayed Enteral Nutrition on Inflammatory Responses and Immune Function Competence in Critically Ill Patients With Prolonged Fasting Completed NCT01834430 Phase 3
43 Extension Study to Evaluate the Long Term Safety and Efficacy of Denosumab in the Treatment of Osteoporosis Completed NCT00523341 Phase 3
44 A Prospective Validation Study of Albumin Kinetics With Tracer 123 I-HSA Completed NCT01686776 Phase 3
45 A Study of Dulaglutide (LY2189265) in Participants With Type II Diabetes Completed NCT02152371 Phase 3 Dulaglutide;Placebo;Insulin Glargine;Metformin
46 Comparison of Endoscopic Sphincterotomy Plus Large-balloon Dilatation and Conventional Treatment for Large CBD Stones Completed NCT02592811 Phase 3
47 A Study of Dulaglutide (LY2189265) in Participants With Type 2 Diabetes Mellitus Completed NCT02597049 Phase 3 Dulaglutide;Placebo;SGLT2 inhibitor;Metformin
48 Study of How Dulaglutide Compares to Placebo in Participants With Type 2 Diabetes Who Are Also on Sulfonylurea Therapy (AWARD-8) Completed NCT01769378 Phase 3 Placebo;Dulaglutide;Glimepiride
49 A Study Comparing the Effect of Dulaglutide With Liraglutide in Type 2 Diabetes Completed NCT01624259 Phase 3 LY2189265;Liraglutide;Metformin
50 Safety and Efficacy of Linagliptin (BI 1356) as Monotherapy or in Combination in Type 2 DM Completed NCT00736099 Phase 3 linagliptine 5 mg;linagliptine 5 mg and pioglitazone 30 mg

Search NIH Clinical Center for Acute Pancreatitis

Genetic Tests for Acute Pancreatitis

Genetic tests related to Acute Pancreatitis:

# Genetic test Affiliating Genes
1 Acute Pancreatitis 29

Anatomical Context for Acute Pancreatitis

MalaCards organs/tissues related to Acute Pancreatitis:

41
Pancreas, Lung, Liver, Neutrophil, Kidney, Testes, Monocytes

Publications for Acute Pancreatitis

Articles related to Acute Pancreatitis:

(show top 50) (show all 2854)
# Title Authors Year
1
Corrigendum to "Pretreatment with obestatin reduces the severity of ischemia/reperfusion-induced acute pancreatitis in rats" [Eur. J. Pharmacol. 760 (2015) 113-121]. ( 30554633 )
2019
2
Hypertriglyceridemia-Associated Drug-Induced Acute Pancreatitis. ( 30531242 )
2019
3
Effect of Early Abdominal Paracentesis Drainage on the Injury of Intestinal Mucosa and Intestinal Microcirculation in Severe Acute Pancreatitis Rats. ( 30531248 )
2019
4
Pseudohyponatremia in Hypertriglyceridemia-Induced Acute Pancreatitis: A Tool for Diagnosis Rather Than Merely a Laboratory Error? ( 30540682 )
2019
5
Inhibiting role of rosiglitazone in the regulation of inflammatory response and protective effects for severe acute pancreatitis in mice. ( 30206968 )
2019
6
microRNA-542-5p protects against acute lung injury in mice with severe acute pancreatitis by suppressing the mitogen-activated protein kinase signaling pathway through the negative regulation of P21-activated kinase 1. ( 30216510 )
2019
7
Insulin-dependent diabetes: A chronic complication to acute pancreatitis in childhood acute lymphoblastic leukemia. ( 30216644 )
2019
8
A Tale of Three Tails and a Cystic Lesion: A Rare Cause of Recurrent Acute Pancreatitis. ( 29961770 )
2018
9
Myxedema Coma Following the Administration of Gonadotropin-releasing Hormone Agonist Complicated by Acute Pancreatitis. ( 29877268 )
2018
10
Cerulein-Induced Acute Pancreatitis Affects Sphingomyelin Signaling Pathway in Rats. ( 29939906 )
2018
11
Pancreaticopleural fistula associated with choledocholithiasis: An infrequent complication of acute pancreatitis. ( 29530342 )
2018
12
Secondary Hypertriglyceridemia Causing Recurrent Acute Pancreatitis with Normal Pancreatic Enzymes. ( 29910554 )
2018
13
Recurrent Acute Pancreatitis in Children: Do not forget the "Worms". ( 29095350 )
2018
14
Acute Pancreatitis and Pancreatic Cancer Risk: A Nationwide Matched-cohort Study in Denmark. ( 29432727 )
2018
15
Management of acute pancreatitis in the first 72 hours. ( 29957661 )
2018
16
Acute pancreatitis: ascaris in the pancreatic duct. ( 29452432 )
2018
17
Intraductal tubulopapillary neoplasm of the pancreas presenting as recurrent acute pancreatitis: A case report. ( 29906691 )
2018
18
Cav 1.2 and Cav 2.2 expression is regulated by different endogenous ghrelin levels in pancreatic acinar cells during acute pancreatitis. ( 29436604 )
2018
19
Therapeutic effect of Bifidobacterium combined with early enteral nutrition in the treatment of severe acute pancreatitis: a pilot study. ( 29949178 )
2018
20
Trimethoprim-sulfamethoxazole induces acute pancreatitis associated with drug-specific cytotoxic T lymphocytes. ( 29940316 )
2018
21
Pediatric case of generalized pustular psoriasis developing acute pancreatitis. ( 29655246 )
2018
22
Pathophysiology and nursing management of acute pancreatitis. ( 29952150 )
2018
23
Protective effect of methylsulfonylmethane in caerulein-induced acute pancreatitis and associated lung injury in mice. ( 29971769 )
2018
24
Colopancreatic Fistula: An Uncommon Complication of Recurrent Acute Pancreatitis. ( 29785309 )
2018
25
Total pancreatectomy and islet autotransplantion for chronic and recurrent acute pancreatitis. ( 29901515 )
2018
26
Late onset acute pancreatitis in <i>P. falciparum</i> malaria - An adverse reaction to intravenous artesunate? ( 29942768 )
2018
27
Endoscopic diagnosis and treatment of biliary obstruction due to acute cholangitis and acute pancreatitis secondary to Fasciola hepatica infection. ( 29350372 )
2018
28
Severe Acute Pancreatitis as an Index Clinical Manifestation of Parathyroid Adenoma. ( 29888149 )
2018
29
Lemierre's syndrome presented with acute pancreatitis. ( 29657730 )
2018
30
Neutrophil-lymphocyte ratio, gamma-glutamyl transpeptidase, lipase, high-density lipoprotein as a panel of factors to predict acute pancreatitis in pregnancy. ( 29952970 )
2018
31
Etiology Is Linked to the Length of Admission in Patients With Acute Pancreatitis: Is Novel Endoscopy an Unrecognized Cause? ( 29424812 )
2018
32
Acute pancreatitis during GLP-1 receptor agonist treatment. A case report. ( 29440961 )
2018
33
Role of thrombophilia in splanchnic venous thrombosis in acute pancreatitis. ( 29720864 )
2018
34
Fluid resuscitation with lactated Ringer's solution vs normal saline in acute pancreatitis: A triple-blind, randomized, controlled trial. ( 29435315 )
2018
35
Gastrointestinal: Recurrent acute pancreatitis with a large fluid collection: Pseudocyst or else? ( 29659085 )
2018
36
Acute Pancreatitis in a Patient with Maple Syrup Urine Disease: A Management Paradox. ( 29681447 )
2018
37
Resolvin D1 Resolve Inflammation in Experimental Acute Pancreatitis by Restoring Autophagic Flux. ( 29974378 )
2018
38
Serum Osteopontin Is Associated With Organ Failure in Patients With Acute Pancreatitis. ( 29424811 )
2018
39
Red cell distribution width and red cell distribution width to total serum calcium ratio as major predictors of severity and mortality in acute pancreatitis. ( 29976140 )
2018
40
Ultrasonic/CT image fusion guidance facilitating percutaneous catheter drainage in treatment of acute pancreatitis complicated with infected walled-off necrosis. ( 29954676 )
2018
41
Recurrent Acute Pancreatitis Significantly Reduces Quality of Life Even in the Absence of Overt Chronic Pancreatitis. ( 29867178 )
2018
42
A Clinical Model for the Early Diagnosis of Acute Pancreatitis in the Emergency Department. ( 29975351 )
2018
43
THE M-RNA, EXPRESSION OF SERCA2 AND NCX1 IN THE PROCESS OF PHARMACOLOGICAL CELL PROTECTION IN EXPERIMENTAL ACUTE PANCREATITIS INDUCED BY TAUROCHOLATE. ( 29947686 )
2018
44
Hepatobiliary and Pancreatic: Segmental arterial mediolysis of pancreaticoduodenal artery accompanied by acute pancreatitis and duodenal obstruction. ( 29691909 )
2018
45
Correction:<i>Epidural analgesia in critically ill patients with acute pancreatitis: the multicentre randomised controlled EPIPAN study protocol</i>. ( 29440166 )
2018
46
Acquisition of tolerance to egg allergy in a child with repeated egg-induced acute pancreatitis. ( 29754972 )
2018
47
What may cause fetus loss from acute pancreatitis in pregnancy: Analysis of 54 cases. ( 29443736 )
2018
48
Coil embolization using microballoon assistance combined with the double-catheter technique for a large superior mesenteric arterial pseudoaneurysm and fistula secondary to acute pancreatitis. ( 29942908 )
2018
49
Single Nucleotide Polymorphisms in the Vitamin D Receptor Gene (<i>VDR</i>) May Have an Impact on Acute Pancreatitis (AP) Development: A Prospective Study in Populations of AP Patients and Alcohol-Abuse Controls. ( 29966312 )
2018
50
Recurrent Acute Pancreatitis: International State-of-the-Science Conference With Recommendations. ( 29894415 )
2018

Variations for Acute Pancreatitis

Expression for Acute Pancreatitis

Search GEO for disease gene expression data for Acute Pancreatitis.

Pathways for Acute Pancreatitis

GO Terms for Acute Pancreatitis

Cellular components related to Acute Pancreatitis according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 extracellular region GO:0005576 9.89 CCK CPB1 CRP CTSB CXCL8 ELANE
2 extracellular space GO:0005615 9.58 CCK CPB1 CRP CTSB CXCL8 ELANE
3 secretory granule GO:0030141 9.33 ELANE MPO PLA2G2A

Biological processes related to Acute Pancreatitis according to GeneCards Suite gene sharing:

(show all 19)
# Name GO ID Score Top Affiliating Genes
1 cytokine-mediated signaling pathway GO:0019221 9.88 CXCL8 IL10 IL18 IL6
2 defense response to Gram-positive bacterium GO:0050830 9.75 CRP IL6 PLA2G2A
3 inflammatory response GO:0006954 9.73 CRP CXCL8 IL10 IL18 IL6 REG3A
4 positive regulation of inflammatory response GO:0050729 9.71 IL18 LPL PLA2G2A
5 positive regulation of smooth muscle cell proliferation GO:0048661 9.69 ELANE IL18 IL6
6 antimicrobial humoral response GO:0019730 9.67 ELANE PLA2G2A REG3A
7 lipid catabolic process GO:0016042 9.62 LPL PLA2G2A PLA2G6 PNLIP
8 acute-phase response GO:0006953 9.58 CRP IL6 REG3A
9 low-density lipoprotein particle remodeling GO:0034374 9.57 MPO PLA2G2A
10 response to molecule of bacterial origin GO:0002237 9.56 CXCL8 IL10
11 neutrophil activation GO:0042119 9.55 CXCL8 IL18
12 negative regulation of lipid storage GO:0010888 9.52 CRP IL6
13 positive regulation of neuroinflammatory response GO:0150078 9.48 IL18 IL6
14 response to yeast GO:0001878 9.46 ELANE MPO
15 type 2 immune response GO:0042092 9.43 IL10 IL18
16 negative regulation of chemokine biosynthetic process GO:0045079 9.37 ELANE IL6
17 positive regulation of macrophage derived foam cell differentiation GO:0010744 9.33 IL18 LPL PLA2G2A
18 regulation of signaling receptor activity GO:0010469 9.17 CCK CXCL8 IL10 IL18 IL6 SCT
19 negative regulation of growth of symbiont in host GO:0044130 9.13 ELANE IL10 MPO

Molecular functions related to Acute Pancreatitis according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 hydrolase activity GO:0016787 9.56 CPB1 CTSB ELANE LPL PLA2G2A PLA2G6
2 cytokine activity GO:0005125 8.92 CXCL8 IL10 IL18 IL6

Sources for Acute Pancreatitis

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