MCID: ACT062
MIFTS: 29

Acute Pericementitis

Categories: Gastrointestinal diseases, Oral diseases

Aliases & Classifications for Acute Pericementitis

MalaCards integrated aliases for Acute Pericementitis:

Name: Acute Pericementitis 12 15
Acute Periodontitis 12 71 32

Classifications:



External Ids:

Disease Ontology 12 DOID:10423
ICD9CM 34 523.33
NCIt 49 C34354
SNOMED-CT 67 21638000
ICD10 32 K05.2
UMLS 71 C0001342

Summaries for Acute Pericementitis

MalaCards based summary : Acute Pericementitis, also known as acute periodontitis, is related to aggressive periodontitis and periodontitis, chronic. An important gene associated with Acute Pericementitis is EDIL3 (EGF Like Repeats And Discoidin Domains 3), and among its related pathways/superpathways are Innate Immune System and Defensins. Affiliated tissues include salivary gland, bone and brain.

Related Diseases for Acute Pericementitis

Diseases related to Acute Pericementitis via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50) (show all 100)
# Related Disease Score Top Affiliating Genes
1 aggressive periodontitis 30.2 TNFSF11 TLR2 IL1B DEFB4A
2 periodontitis, chronic 30.2 TNFSF11 IL1B
3 periodontitis 29.6 TNFSF11 TLR2 IL1B DEFB4A
4 osteomyelitis 29.3 TNFSF11 TLR2 IL1B
5 gingivitis 29.1 TLR2 IL1B DEFB4A
6 photokeratitis 10.3 IL1B DEFB4B
7 prosthetic joint infection 10.2 TLR2 IL1B
8 congenital cytomegalovirus 10.2 TLR2 IL1B
9 pneumonic tularemia 10.2 TLR2 IL1B
10 tularemia 10.2 TLR2 IL1B
11 chlamydia pneumonia 10.2 TLR2 IL1B
12 silo filler's disease 10.2 TLR2 IL1B
13 suppurative otitis media 10.2 TLR2 IL1B
14 dental pulp disease 10.2 TLR2 IL1B
15 primary systemic mycosis 10.2 TLR2 IL1B
16 blood group, globoside system 10.2 TLR2 IL1B
17 endometrial disease 10.1 TLR2 IL1B
18 pyelitis 10.1 TLR2 IL1B
19 endophthalmitis 10.1 TLR2 IL1B
20 streptococcus pneumonia 10.1 TLR2 IL1B
21 amebiasis 10.1 TLR2 IL1B
22 fallopian tube disease 10.1 TLR2 IL1B
23 scrub typhus 10.1 TLR2 IL1B
24 endometritis 10.1 TLR2 IL1B
25 idiopathic hypercalciuria 10.1 TNFSF11 IL1B
26 listeriosis 10.1 TLR2 IL1B
27 tooth resorption 10.1 TNFSF11 IL1B
28 chronic recurrent multifocal osteomyelitis 10.1 TNFSF11 IL1B
29 tinea pedis 10.1 DEFB4B DEFB4A
30 poems syndrome 10.1 TNFSF11 IL1B
31 perinatal necrotizing enterocolitis 10.1 TLR2 IL1B
32 marginal corneal ulcer 10.1 DEFB4B DEFB4A
33 multicentric carpotarsal osteolysis syndrome 10.1 TNFSF11 IL1B
34 middle ear disease 10.1 TLR2 IL1B
35 endocardium disease 10.1 TLR2 IL1B
36 coccidiosis 10.1 TLR2 IL1B
37 conjunctival disease 10.1 TLR2 IL1B
38 dysentery 10.1 TLR2 IL1B
39 root resorption 10.1 TNFSF11 IL1B
40 blau syndrome 10.1 TLR2 IL1B
41 periapical granuloma 10.1 TNFSF11 TLR2
42 ischemic bone disease 10.1 TNFSF11 IL1B
43 anus disease 10.1 TLR2 IL1B
44 extrapulmonary tuberculosis 10.0 TLR2 IL1B
45 bacterial sepsis 10.0 TLR2 IL1B
46 leptospirosis 10.0 TLR2 IL1B
47 crohn's colitis 10.0 IL1B DEFB4A
48 rectal disease 10.0 TLR2 IL1B
49 preterm premature rupture of the membranes 10.0 TLR2 IL1B
50 vulvovaginal candidiasis 10.0 TLR2 DEFB4A

Comorbidity relations with Acute Pericementitis via Phenotypic Disease Network (PDN):


Dental Caries

Graphical network of the top 20 diseases related to Acute Pericementitis:



Diseases related to Acute Pericementitis

Symptoms & Phenotypes for Acute Pericementitis

Drugs & Therapeutics for Acute Pericementitis

Search Clinical Trials , NIH Clinical Center for Acute Pericementitis

Genetic Tests for Acute Pericementitis

Anatomical Context for Acute Pericementitis

MalaCards organs/tissues related to Acute Pericementitis:

40
Salivary Gland, Bone, Brain

Publications for Acute Pericementitis

Articles related to Acute Pericementitis:

(show all 32)
# Title Authors PMID Year
1
Improved oral hygiene is associated with decreased risk of new-onset diabetes: a nationwide population-based cohort study. 61
32128623 2020
2
A multicenter retrospective investigation on the efficacy of perioperative oral management in cancer patients. 61
32150054 2020
3
Antibiotic prescribing for endodontic infections: a survey of dental students in Italy. 61
30982994 2019
4
Correction of Acute Parodontitis with Indolicidin Analogues. 61
31177448 2019
5
Trends, demographics, and conditions of emergency dental visits in Taiwan 1997-2013: A nationwide population-based retrospective study. 61
30527437 2019
6
Torturous path of an elastic gap band: Interdisciplinary approach to orthodontic treatment for a young patient who lost both maxillary central incisors after do-it-yourself treatment. 61
30477782 2018
7
Nanotechnology in Phytotherapy: Antiinflammatory Effect of a Nanostructured Thymol Gel from Lippia sidoides in Acute Periodontitis in Rats. 61
26553130 2016
8
Treatment of Acute Periodontal Abscesses Using the Biofilm Decontamination Approach: A Case Report Study. 61
26697553 2016
9
Selection of an optimal treatment method for acute periodontitis disease. 61
20703669 2012
10
Outcomes in patients visiting hospital emergency departments in the United States because of periodontal conditions. 61
21138352 2011
11
Anti-inflammatory effect of alpha, beta-Amyrin, a pentacyclic triterpene from Protium heptaphyllum in rat model of acute periodontitis. 61
18046512 2008
12
New role of the trigeminal nerve as a neuronal pathway signaling brain in acute periodontitis: participation of local prostaglandins. 61
16902799 2006
13
Demographics of pediatric head and neck infections in a tertiary care hospital. 61
16735893 2006
14
Reduced inflammation and tissue damage in transgenic rabbits overexpressing 15-lipoxygenase and endogenous anti-inflammatory lipid mediators. 61
14662892 2003
15
Clinical and microbiological changes in a child with rapid alveolar bone loss and refill. 61
12515055 2002
16
Antibiotic prescribing for dental conditions: a community-based study in southern Italy. 61
11892902 2002
17
[Intraoral protrusion devices in obstructive sleep apnea. Dental findings and possible treatments]. 61
11963784 2002
18
[The treatment of acute periodontitis using sodium diclofenac experimentally]. 61
7482611 1995
19
[The characteristics of the development of caries in human dental fissures based on microhardness data. Its diagnosis, treatment and prevention]. 61
7770892 1995
20
[Proglumetacin in acute periodontitis. Effectiveness and tolerance]. 61
1778279 1991
21
Clinical experience in the treatment of dental pain. 61
1810525 1991
22
An in-vitro study of oral therapeutic doses of co-trimoxazole and erythromycin stearate on abnormal polymorphonuclear leucocyte migration. 61
3486178 1986
23
Studies of a periodontal tissue lesion in the rat, untreated or treated with chlorhexidine digluconate. 61
6947996 1981
24
[Therapy of acute periodontitis]. 61
6932555 1980
25
[Experience with the treatment of complicated acute periodontitis]. 61
802439 1976
26
A simple surgical treatment for acute periodontitis in the dog. 61
1041095 1975
27
[Diagnosis of acute periodontitis]. 61
4536026 1974
28
[The importance of sensitization for the development of acute periodontitis]. 61
5286961 1971
29
[Etio-pathogenetics of juvenile acute periodontitis (desmodontosi or periodontal syndrome) and the Papillon-Lefèvre syndrome]. 61
5285355 1971
30
[The phagocytic activity and metabolism of leukocytes of the peripheral blood in acute periodontitis and osteomyelitis]. 61
5232934 1967
31
[Acute periodontitis]. 61
14829827 1951
32
[A method of local anesthetization in the treatment of acute periodontitis]. 61
21012726 1945

Variations for Acute Pericementitis

Expression for Acute Pericementitis

Search GEO for disease gene expression data for Acute Pericementitis.

Pathways for Acute Pericementitis

Pathways related to Acute Pericementitis according to GeneCards Suite gene sharing:

(show all 15)
# Super pathways Score Top Affiliating Genes
1
Show member pathways
13.61 TPR TNFSF11 TLR2 IL1B DEFB4B DEFB4A
2
Show member pathways
12 TLR2 DEFB4B DEFB4A
3
Show member pathways
11.86 TLR2 IL1B ALOX5
4 11.77 TNFSF11 TLR2 IL1B ALOX5
5 11.76 IL1B DEFB4B DEFB4A
6
Show member pathways
11.65 TLR2 IL1B DEFB4A
7 11.3 TNFSF11 TLR2 IL1B
8
Show member pathways
11.26 TLR2 IL1B DEFB4B DEFB4A
9 11.25 TLR2 IL1B
10 11.22 TLR2 IL1B
11 11.18 TNFSF11 IL1B
12 11 IL1B ALOX12
13
Show member pathways
10.89 ALOX5 ALOX12
14 10.83 TLR2 IL1B
15 10.75 ALOX5 ALOX12

GO Terms for Acute Pericementitis

Cellular components related to Acute Pericementitis according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 extracellular region GO:0005576 9.1 TNFSF11 IL1B EDIL3 DEFB4B DEFB4A ALOX5

Biological processes related to Acute Pericementitis according to GeneCards Suite gene sharing:

(show all 19)
# Name GO ID Score Top Affiliating Genes
1 cytokine-mediated signaling pathway GO:0019221 9.75 TNFSF11 IL1B ALOX5
2 positive regulation of gene expression GO:0010628 9.71 TNFSF11 TLR2 IL1B ALOX12
3 positive regulation of NF-kappaB transcription factor activity GO:0051092 9.63 TNFSF11 TLR2 IL1B
4 positive chemotaxis GO:0050918 9.58 DEFB4B DEFB4A
5 positive regulation of interleukin-6 secretion GO:2000778 9.57 TLR2 IL1B
6 killing of cells of other organism GO:0031640 9.56 DEFB4B DEFB4A
7 arachidonic acid metabolic process GO:0019369 9.55 ALOX5 ALOX12
8 lipopolysaccharide-mediated signaling pathway GO:0031663 9.54 TLR2 IL1B
9 positive regulation of interleukin-8 production GO:0032757 9.52 TLR2 IL1B
10 long-chain fatty acid biosynthetic process GO:0042759 9.51 ALOX5 ALOX12
11 defense response to Gram-positive bacterium GO:0050830 9.5 TLR2 DEFB4B DEFB4A
12 linoleic acid metabolic process GO:0043651 9.49 ALOX5 ALOX12
13 positive regulation of protein export from nucleus GO:0046827 9.48 TPR IL1B
14 leukotriene metabolic process GO:0006691 9.43 TLR2 ALOX5
15 lipoxygenase pathway GO:0019372 9.37 ALOX5 ALOX12
16 hepoxilin biosynthetic process GO:0051122 9.26 ALOX5 ALOX12
17 lipid oxidation GO:0034440 9.16 ALOX5 ALOX12
18 immune response GO:0006955 9.02 TNFSF11 TLR2 IL1B DEFB4B DEFB4A
19 lipoxin biosynthetic process GO:2001301 8.96 ALOX5 ALOX12

Molecular functions related to Acute Pericementitis according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 chemoattractant activity GO:0042056 9.16 DEFB4B DEFB4A
2 oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen GO:0016702 8.96 ALOX5 ALOX12
3 CCR6 chemokine receptor binding GO:0031731 8.62 DEFB4B DEFB4A

Sources for Acute Pericementitis

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
17 EFO
18 ExPASy
19 FMA
28 GO
29 GTR
30 HMDB
31 HPO
32 ICD10
33 ICD10 via Orphanet
34 ICD9CM
35 IUPHAR
36 KEGG
37 LifeMap
39 LOVD
41 MedGen
43 MeSH
44 MESH via Orphanet
45 MGI
48 NCI
49 NCIt
50 NDF-RT
53 NINDS
54 Novoseek
56 OMIM
57 OMIM via Orphanet
61 PubMed
63 QIAGEN
68 SNOMED-CT via HPO
69 TGDB
70 Tocris
71 UMLS
72 UMLS via Orphanet
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