MCID: ACT062
MIFTS: 29

Acute Pericementitis

Categories: Gastrointestinal diseases, Oral diseases

Aliases & Classifications for Acute Pericementitis

MalaCards integrated aliases for Acute Pericementitis:

Name: Acute Pericementitis 12 15
Acute Periodontitis 12 71 32

Classifications:



External Ids:

Disease Ontology 12 DOID:10423
ICD9CM 34 523.3 523.33
NCIt 49 C34354
SNOMED-CT 67 21638000
ICD10 32 K05.2
UMLS 71 C0001342

Summaries for Acute Pericementitis

MalaCards based summary : Acute Pericementitis, also known as acute periodontitis, is related to aggressive periodontitis and periodontitis. An important gene associated with Acute Pericementitis is EDIL3 (EGF Like Repeats And Discoidin Domains 3), and among its related pathways/superpathways are TRAF Pathway and NF-kappaB Signaling. Affiliated tissues include bone, salivary gland and brain, and related phenotypes are hematopoietic system and immune system

Related Diseases for Acute Pericementitis

Diseases related to Acute Pericementitis via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50) (show all 53)
# Related Disease Score Top Affiliating Genes
1 aggressive periodontitis 31.1 TNFSF11 TLR2
2 periodontitis 10.4
3 periapical periodontitis 10.1 TNFSF11 TLR2
4 neurosyphilis 10.1 TLR6 TLR2
5 periapical granuloma 10.1 TNFSF11 TLR2
6 superficial basal cell carcinoma 10.1 TLR6 TLR2
7 tuberculous meningitis 10.1 TLR2 ALOX5
8 gingival disease 10.1 TNFSF11 TLR2
9 combat disorder 10.1 TLR6 TLR2
10 chlamydia pneumonia 10.1 TLR6 TLR2
11 myd88 deficiency 10.1 TLR6 TLR2
12 irak4 deficiency 10.1 TLR6 TLR2
13 anogenital venereal wart 10.0 TLR6 TLR2
14 endometrial disease 10.0 TLR6 TLR2
15 streptococcus pneumonia 10.0 TLR6 TLR2
16 herpangina 10.0 TLR6 TLR2
17 periodontitis, chronic 10.0
18 perinatal necrotizing enterocolitis 10.0 TLR6 TLR2
19 vaginal disease 10.0 TLR6 TLR2
20 coccidiosis 10.0 TLR6 TLR2
21 rectal disease 10.0 TLR6 TLR2
22 invasive aspergillosis 10.0 TLR6 TLR2
23 pleurisy 10.0 TLR2 ALOX5
24 opportunistic mycosis 9.9 TLR6 TLR2
25 infective endocarditis 9.9 TLR6 TLR2
26 plague 9.9 TLR6 TLR2
27 papillon-lefevre syndrome 9.9
28 pelvic inflammatory disease 9.8 TLR6 TLR2
29 toxoplasmosis 9.8 TLR2 ALOX5 ALOX12
30 filariasis 9.8 TLR6 TLR2
31 bone inflammation disease 9.7 TNFSF11 TLR6 TLR2
32 leukocyte adhesion deficiency, type i 9.7
33 down syndrome 9.7
34 chediak-higashi syndrome 9.7
35 immune deficiency disease 9.7
36 cytomegalovirus retinitis 9.7
37 neuroretinitis 9.7
38 osteomyelitis 9.7
39 lymphocytic leukemia 9.7
40 acute leukemia 9.7
41 gingivitis 9.7
42 retinitis 9.7
43 gastritis 9.7
44 active peptic ulcer disease 9.7
45 herpes simplex 9.7
46 encephalitis 9.7
47 granulocytopenia 9.7
48 cytomegalovirus infection 9.7
49 benign idiopathic neonatal seizures 9.7
50 salmonellosis 9.7 TLR6 TLR2

Comorbidity relations with Acute Pericementitis via Phenotypic Disease Network (PDN):


Dental Caries

Graphical network of the top 20 diseases related to Acute Pericementitis:



Diseases related to Acute Pericementitis

Symptoms & Phenotypes for Acute Pericementitis

MGI Mouse Phenotypes related to Acute Pericementitis:

45
# Description MGI Source Accession Score Top Affiliating Genes
1 hematopoietic system MP:0005397 9.5 ALOX12 ALOX15 ALOX5 EDIL3 TLR2 TLR6
2 immune system MP:0005387 9.17 ALOX12 ALOX15 ALOX5 EDIL3 TLR2 TLR6

Drugs & Therapeutics for Acute Pericementitis

Search Clinical Trials , NIH Clinical Center for Acute Pericementitis

Genetic Tests for Acute Pericementitis

Anatomical Context for Acute Pericementitis

MalaCards organs/tissues related to Acute Pericementitis:

40
Bone, Salivary Gland, Brain

Publications for Acute Pericementitis

Articles related to Acute Pericementitis:

(show all 30)
# Title Authors PMID Year
1
Antibiotic prescribing for endodontic infections: a survey of dental students in Italy. 61
30982994 2019
2
Correction of Acute Parodontitis with Indolicidin Analogues. 61
31177448 2019
3
Trends, demographics, and conditions of emergency dental visits in Taiwan 1997-2013: A nationwide population-based retrospective study. 61
30527437 2019
4
Torturous path of an elastic gap band: Interdisciplinary approach to orthodontic treatment for a young patient who lost both maxillary central incisors after do-it-yourself treatment. 61
30477782 2018
5
Treatment of Acute Periodontal Abscesses Using the Biofilm Decontamination Approach: A Case Report Study. 61
26697553 2016
6
Nanotechnology in Phytotherapy: Antiinflammatory Effect of a Nanostructured Thymol Gel from Lippia sidoides in Acute Periodontitis in Rats. 61
26553130 2016
7
Selection of an optimal treatment method for acute periodontitis disease. 61
20703669 2012
8
Outcomes in patients visiting hospital emergency departments in the United States because of periodontal conditions. 61
21138352 2011
9
Anti-inflammatory effect of alpha, beta-Amyrin, a pentacyclic triterpene from Protium heptaphyllum in rat model of acute periodontitis. 61
18046512 2008
10
New role of the trigeminal nerve as a neuronal pathway signaling brain in acute periodontitis: participation of local prostaglandins. 61
16902799 2006
11
Demographics of pediatric head and neck infections in a tertiary care hospital. 61
16735893 2006
12
Reduced inflammation and tissue damage in transgenic rabbits overexpressing 15-lipoxygenase and endogenous anti-inflammatory lipid mediators. 61
14662892 2003
13
Clinical and microbiological changes in a child with rapid alveolar bone loss and refill. 61
12515055 2002
14
Antibiotic prescribing for dental conditions: a community-based study in southern Italy. 61
11892902 2002
15
[Intraoral protrusion devices in obstructive sleep apnea. Dental findings and possible treatments]. 61
11963784 2002
16
[The treatment of acute periodontitis using sodium diclofenac experimentally]. 61
7482611 1995
17
[The characteristics of the development of caries in human dental fissures based on microhardness data. Its diagnosis, treatment and prevention]. 61
7770892 1995
18
[Proglumetacin in acute periodontitis. Effectiveness and tolerance]. 61
1778279 1991
19
Clinical experience in the treatment of dental pain. 61
1810525 1991
20
An in-vitro study of oral therapeutic doses of co-trimoxazole and erythromycin stearate on abnormal polymorphonuclear leucocyte migration. 61
3486178 1986
21
Studies of a periodontal tissue lesion in the rat, untreated or treated with chlorhexidine digluconate. 61
6947996 1981
22
[Therapy of acute periodontitis]. 61
6932555 1980
23
[Experience with the treatment of complicated acute periodontitis]. 61
802439 1976
24
A simple surgical treatment for acute periodontitis in the dog. 61
1041095 1975
25
[Diagnosis of acute periodontitis]. 61
4536026 1974
26
[The importance of sensitization for the development of acute periodontitis]. 61
5286961 1971
27
[Etio-pathogenetics of juvenile acute periodontitis (desmodontosi or periodontal syndrome) and the Papillon-Lefèvre syndrome]. 61
5285355 1971
28
[The phagocytic activity and metabolism of leukocytes of the peripheral blood in acute periodontitis and osteomyelitis]. 61
5232934 1967
29
[Acute periodontitis]. 61
14829827 1951
30
[A method of local anesthetization in the treatment of acute periodontitis]. 61
21012726 1945

Variations for Acute Pericementitis

Expression for Acute Pericementitis

Search GEO for disease gene expression data for Acute Pericementitis.

Pathways for Acute Pericementitis

GO Terms for Acute Pericementitis

Biological processes related to Acute Pericementitis according to GeneCards Suite gene sharing:

(show all 22)
# Name GO ID Score Top Affiliating Genes
1 positive regulation of gene expression GO:0010628 9.85 TNFSF11 TLR6 TLR2 ALOX12
2 inflammatory response GO:0006954 9.81 TLR6 TLR2 ALOX5 ALOX15
3 cytokine-mediated signaling pathway GO:0019221 9.78 TNFSF11 ALOX5 ALOX15
4 positive regulation of NF-kappaB transcription factor activity GO:0051092 9.73 TNFSF11 TLR6 TLR2
5 toll-like receptor signaling pathway GO:0002224 9.6 TLR6 TLR2
6 positive regulation of cell-substrate adhesion GO:0010811 9.59 EDIL3 ALOX15
7 MyD88-dependent toll-like receptor signaling pathway GO:0002755 9.58 TLR6 TLR2
8 arachidonic acid metabolic process GO:0019369 9.58 ALOX15 ALOX12
9 microglial cell activation GO:0001774 9.57 TLR6 TLR2
10 regulation of cytokine secretion GO:0050707 9.54 TLR6 TLR2
11 cell activation GO:0001775 9.52 TLR6 TLR2
12 cellular response to diacyl bacterial lipopeptide GO:0071726 9.49 TLR6 TLR2
13 lipoxin biosynthetic process GO:2001301 9.48 ALOX5 ALOX12
14 hepoxilin biosynthetic process GO:0051122 9.46 ALOX15 ALOX12
15 toll-like receptor TLR6:TLR2 signaling pathway GO:0038124 9.43 TLR6 TLR2
16 nitric oxide metabolic process GO:0046209 9.4 TLR6 TLR2
17 lipoxin A4 biosynthetic process GO:2001303 9.37 ALOX15 ALOX12
18 long-chain fatty acid biosynthetic process GO:0042759 9.33 ALOX5 ALOX15 ALOX12
19 detection of diacyl bacterial lipopeptide GO:0042496 9.32 TLR6 TLR2
20 response to bacterial lipoprotein GO:0032493 9.26 TLR6 TLR2
21 lipoxygenase pathway GO:0019372 9.13 ALOX5 ALOX15 ALOX12
22 leukotriene metabolic process GO:0006691 8.8 TLR2 ALOX5 ALOX15

Molecular functions related to Acute Pericementitis according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 iron ion binding GO:0005506 9.58 ALOX5 ALOX15 ALOX12
2 dioxygenase activity GO:0051213 9.5 ALOX5 ALOX15 ALOX12
3 lipopeptide binding GO:0071723 9.37 TLR6 TLR2
4 arachidonate 15-lipoxygenase activity GO:0050473 9.26 ALOX15 ALOX12
5 arachidonate 12-lipoxygenase activity GO:0004052 9.16 ALOX15 ALOX12
6 hepoxilin-epoxide hydrolase activity GO:0047977 8.96 ALOX15 ALOX12
7 oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen GO:0016702 8.8 ALOX5 ALOX15 ALOX12

Sources for Acute Pericementitis

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
17 EFO
18 ExPASy
19 FMA
28 GO
29 GTR
30 HMDB
31 HPO
32 ICD10
33 ICD10 via Orphanet
34 ICD9CM
35 IUPHAR
36 KEGG
37 LifeMap
39 LOVD
41 MedGen
43 MeSH
44 MESH via Orphanet
45 MGI
48 NCI
49 NCIt
50 NDF-RT
53 NINDS
54 Novoseek
56 OMIM
57 OMIM via Orphanet
61 PubMed
63 QIAGEN
68 SNOMED-CT via HPO
69 TGDB
70 Tocris
71 UMLS
72 UMLS via Orphanet
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