MCID: ACT062
MIFTS: 27

Acute Pericementitis

Categories: Gastrointestinal diseases, Oral diseases

Aliases & Classifications for Acute Pericementitis

MalaCards integrated aliases for Acute Pericementitis:

Name: Acute Pericementitis 12 15
Acute Periodontitis 12 74

Classifications:



External Ids:

Disease Ontology 12 DOID:10423
ICD9CM 36 523.3 523.33
NCIt 51 C34354
SNOMED-CT 69 21638000
ICD10 34 K05.2
UMLS 74 C0001342

Summaries for Acute Pericementitis

MalaCards based summary : Acute Pericementitis, also known as acute periodontitis, is related to aggressive periodontitis and periodontal disease. An important gene associated with Acute Pericementitis is FOS (Fos Proto-Oncogene, AP-1 Transcription Factor Subunit), and among its related pathways/superpathways are Regulation of TP53 Activity and Endometrial cancer. The drugs Estradiol and Ethinyl Estradiol have been mentioned in the context of this disorder. Affiliated tissues include bone, testes and b cells.

Related Diseases for Acute Pericementitis

Diseases related to Acute Pericementitis via text searches within MalaCards or GeneCards Suite gene sharing:

# Related Disease Score Top Affiliating Genes
1 aggressive periodontitis 10.3
2 periodontal disease 10.1
3 periodontitis 10.1

Comorbidity relations with Acute Pericementitis via Phenotypic Disease Network (PDN):


Dental Caries

Symptoms & Phenotypes for Acute Pericementitis

Drugs & Therapeutics for Acute Pericementitis

Drugs for Acute Pericementitis (from DrugBank, HMDB, Dgidb, PharmGKB, IUPHAR, NovoSeek, BitterDB):

(show top 50) (show all 79)
# Name Status Phase Clinical Trials Cas Number PubChem Id
1
Estradiol Approved, Investigational, Vet_approved Phase 4 50-28-2 5757
2
Ethinyl Estradiol Approved Phase 4 57-63-6 5991
3
Amoxicillin Approved, Vet_approved Phase 4,Phase 2,Phase 3,Phase 1,Not Applicable 26787-78-0 33613
4
Polyestradiol phosphate Approved Phase 4 28014-46-2
5
Moxifloxacin Approved, Investigational Phase 4 354812-41-2, 151096-09-2 152946
6
Metronidazole Approved Phase 4,Phase 2,Phase 3,Phase 1,Not Applicable 443-48-1 4173
7
Norgestimate Approved, Investigational Phase 4 35189-28-7 6540478
8
Chlorhexidine Approved, Vet_approved Phase 4 55-56-1 2713 9552079
9 sodium fluoride Approved Phase 4 7681-49-4
10
Triclosan Approved, Investigational Phase 4 3380-34-5 5564
11 Anti-Bacterial Agents Phase 4,Phase 2,Phase 3,Phase 1,Not Applicable
12 Contraceptive Agents Phase 4
13 Anti-Infective Agents Phase 4,Phase 2,Phase 3,Phase 1,Not Applicable
14 Contraceptives, Oral Phase 4
15 Anesthetics Phase 4,Not Applicable
16 Antiparasitic Agents Phase 4,Phase 2,Phase 3,Phase 1
17 Topoisomerase Inhibitors Phase 4
18 Antibiotics, Antitubercular Phase 4,Phase 2,Phase 3,Phase 1,Not Applicable
19 Estradiol 17 beta-cypionate Phase 4
20 Estradiol 3-benzoate Phase 4
21 Norgestimate, ethinyl estradiol drug combination Phase 4
22 Contraceptives, Oral, Combined Phase 4
23 Antiprotozoal Agents Phase 4,Phase 2,Phase 3,Phase 1
24 Chlorhexidine gluconate Phase 4
25 Antimetabolites Phase 4
26 Hypolipidemic Agents Phase 4
27 Cariostatic Agents Phase 4
28 Anti-Infective Agents, Local Phase 4
29 Protective Agents Phase 4
30 Fluorides Phase 4
31 Listerine Phase 4
32 Lipid Regulating Agents Phase 4
33 Anesthetics, Local Phase 4
34
Clarithromycin Approved Phase 2, Phase 3,Phase 3,Not Applicable 81103-11-9 84029
35
Aspirin Approved, Vet_approved Phase 2, Phase 3,Phase 3 50-78-2 2244
36 Cytochrome P-450 CYP3A Inhibitors Phase 2, Phase 3,Phase 3,Not Applicable
37 Cytochrome P-450 Enzyme Inhibitors Phase 2, Phase 3,Phase 3,Not Applicable
38 Cyclooxygenase Inhibitors Phase 2, Phase 3,Phase 3
39 Anti-Inflammatory Agents, Non-Steroidal Phase 2, Phase 3,Phase 3
40 Antipyretics Phase 2, Phase 3,Phase 3
41 Anti-Inflammatory Agents Phase 2, Phase 3,Phase 3
42 Fibrinolytic Agents Phase 2, Phase 3,Phase 3
43 Peripheral Nervous System Agents Phase 2, Phase 3,Phase 3
44 Platelet Aggregation Inhibitors Phase 2, Phase 3,Phase 3
45 Omega 3 Fatty Acid Phase 2, Phase 3,Phase 3
46 Antirheumatic Agents Phase 2, Phase 3,Phase 3
47 Analgesics, Non-Narcotic Phase 2, Phase 3,Phase 3
48 Analgesics Phase 2, Phase 3,Phase 3
49
Doxycycline Approved, Investigational, Vet_approved Phase 1, Phase 2 564-25-0 54671203
50 Antimalarials Phase 1, Phase 2

Interventional clinical trials:

(show all 46)
# Name Status NCT ID Phase Drugs
1 Efficacy of Three Antibiotic Protocols for Aggressive Periodontitis Treatment Unknown status NCT02839421 Phase 4 Scaling and Root Planing combined with moxifloxacin
2 Adjunctive Systemic Administration of Moxifloxacin in the Treatment of Aggressive Periodontitis Completed NCT02125812 Phase 4
3 Evaluation of Efficacy of Full-mouth Disinfection in Generalized Aggressive Periodontitis Patients Completed NCT02466646 Phase 4 Klorhex® Gel, rinse and sprey
4 Treatment of Aggressive Periodontitis With Repeated Adjunctive Antimicrobial Photodynamic Therapy Completed NCT02049008 Phase 4
5 Triclosan as Adjunctive Therapy in the Plaque Control in Children From Generalized Aggressive Periodontitis Families. Completed NCT03642353 Phase 4 Triclosan;Placebo
6 Host Modulatory Effects of β-glucan on Localized Aggressive Periodontitis Completed NCT02402296 Phase 4 β-1,3/1,6-D-glucan
7 Alternative Antibiotic Regime in the Treatment of GAgP Completed NCT02223702 Phase 4 Amoxicillin;Metronidazole;Moxifloxacin
8 Enamel Matrix Proteins in the Treatment of Intrabony Defects in Patients With Aggressive and Chronic Periodontitis Completed NCT03025204 Phase 4
9 Two Different Antibiotic Agents to Treat Generalized Aggressive Periodontitis Completed NCT02969928 Phase 2, Phase 3 Clarithromycin;Amoxicillin;Metronidazole
10 Periodontal Debridement Associated With Systemic Antibiotics and Single/Repeated PDT to Treat Aggressive Periodontitis Completed NCT03132714 Phase 2, Phase 3 Amoxicillin 500mg;Metronidazole 400mg;Clarithromycin 500mg
11 Omega-3 Fatty Acids Plus Low-dose Aspirin Daily Supplementation in Surgical Therapy to Treat Aggressive Periodontitis Recruiting NCT03093207 Phase 2, Phase 3 Aspirin
12 Omega-3 Plus Low-dose Aspirin Daily Supplementation in Non-surgical Therapy to Treat Aggressive Periodontitis Recruiting NCT03093246 Phase 2, Phase 3 Aspirin
13 Doxycycline in the Treatment of Aggressive Periodontitis Completed NCT03727620 Phase 1, Phase 2 amoxicillin plus metronidazole;Doxycycline
14 The Affect of Orthodontic Treatment on the Periodontal Status of Patients With Aggressive Periodontitis Unknown status NCT01510808
15 Subgingival Microbiome Following Mechanical Treatment and it's Effect on Peri-implant Sub-mucosa in Aggressive Periodontitis Patients Unknown status NCT03090282
16 Polymorphonuclear Cells' Sensitivity to Aggregatibacter Actinomycetemcomitans Bacteria in Patients With Aggressive Periodontitis Unknown status NCT02010307 Not Applicable
17 Chronic Presence of Epstein Barr Virus in Epithelial Cells From Gingiva is Associated With Periodontitis Unknown status NCT01246596 Not Applicable
18 B Cell Functions in Periodontitis Unknown status NCT02833285
19 Immunolocalization of 1,25,Dihydroxyvitamin D3 in Aggressive Periodontitis Patients Completed NCT02282800
20 Gene Expression Profiles in Generalized Aggressive Periodontitis: A Gene Network-based Microarray Analysis Completed NCT02327533
21 Effects of Smoking on Non-surgical Periodontal Therapy in Generalized Aggressive Periodontitis Completed NCT03512938 Not Applicable
22 Effects Of Adjunctive Photodynamic Therapy To Non-Surgical Periodontal Treatment In Patients With Generalized Aggressive Periodontitis Completed NCT03412331 Not Applicable
23 Gingival Crevicular Fluid Levels Of Monocyte Chemoattractant Protein-1 Completed NCT02927704
24 Frequency Of MCP-1 And CCR2 Gene Polymorphisms And Its Effect On Gene Expression In Patients With AgP Completed NCT02817568
25 Effects of Er,Cr:YSGG, Diode Lasers on GCF Cytokines Levels Completed NCT03034824 Not Applicable
26 Clarithromycin as Adjuvant to Periodontal Debridement Completed NCT02829983 Not Applicable Clarithromycin;Placebo
27 Smoking Influence on Apoptosis in Periodontitis Completed NCT02111005
28 Tissue Alterations in Aggressive and Chronic Periodontitis Completed NCT03625414
29 Nonsurgical Periodontal Treatment Associated or Not With Systemic Antibiotics and Photodynamic Therapy Completed NCT03142776 Not Applicable systemic clarithromycin
30 Effect of Surgical Therapy on RANKL/OPG (Osteoprotegerin) System Completed NCT02190773
31 Estimation of Pentrexin-3 Levels in GCF and Saliva of Patients With Periodontal Disease Completed NCT03128502
32 Clinical, Immunological and Microbiological Evaluation of Experimental Gingivitis and Peri-implant Mucositis Completed NCT03713567 Not Applicable
33 Nitro-oxidative Stress in Periodontitis Completed NCT02127203
34 TNF-α/HIF-1α/VEGF Pathway in Periodontal Diseases Completed NCT03558906
35 Active Matrix Metalloproteinase-8 (aMMP-8) Chair-side Test in Different Periodontal Disease Completed NCT03527901
36 The Importance of Periostin in Periodontal Health and Disease Completed NCT01180920
37 Gingival Bleeding and Von Willebrand Disease Typ 2 and 3 Completed NCT03078595
38 Perforated Collagen Membrane With Nanohydroxyapatite for Intrabony Defects Completed NCT03399279 Not Applicable
39 Immediate Implant Placement in Aggressive Periodontitis Recruiting NCT03218228 Not Applicable
40 EMD for Treatment of Proximal Class-II Furcation Involvements Recruiting NCT03320135 Not Applicable
41 Mechanisms and Treatment Response of Aggressive Periodontitis in Children Active, not recruiting NCT01330719 Not Applicable
42 Comparison Between Surgical Access and Repeated Applications of APDT Active, not recruiting NCT03140059 Not Applicable
43 Interaction Between Immune Cells and Bacteria Associated With Periodontitis Active, not recruiting NCT03225950
44 Long-term Results After Systematic Periodontal Therapy Enrolling by invitation NCT03048045
45 Clinical and Radiographic Evaluation of Guided Tissue Regeneration With Radiation-sterilized Allogenic Bone Grafts or Xenogenic Grafts for the Treatment of Intrabony Defects in Aggressive Periodontitis Not yet recruiting NCT03340012 Not Applicable
46 Analysis of Osteoimmune Interactions Linking Inflammation and Bone Destruction in Aggressive Periodontitis Terminated NCT01993368 Not Applicable

Search NIH Clinical Center for Acute Pericementitis

Genetic Tests for Acute Pericementitis

Anatomical Context for Acute Pericementitis

MalaCards organs/tissues related to Acute Pericementitis:

42
Bone, Testes, B Cells, Monocytes, Brain

Publications for Acute Pericementitis

Articles related to Acute Pericementitis:

# Title Authors Year
1
Nanotechnology in Phytotherapy: Antiinflammatory Effect of a Nanostructured Thymol Gel from Lippia sidoides in Acute Periodontitis in Rats. ( 26553130 )
2015
2
Selection of an optimal treatment method for acute periodontitis disease. ( 20703669 )
2012
3
Anti-inflammatory effect of alpha, beta-Amyrin, a pentacyclic triterpene from Protium heptaphyllum in rat model of acute periodontitis. ( 18046512 )
2008
4
New role of the trigeminal nerve as a neuronal pathway signaling brain in acute periodontitis: participation of local prostaglandins. ( 16902799 )
2006
5
A simple surgical treatment for acute periodontitis in the dog. ( 1041095 )
1975
6
[A method of local anesthetization in the treatment of acute periodontitis]. ( 21012726 )
1945

Variations for Acute Pericementitis

Expression for Acute Pericementitis

Search GEO for disease gene expression data for Acute Pericementitis.

Pathways for Acute Pericementitis

GO Terms for Acute Pericementitis

Biological processes related to Acute Pericementitis according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 aging GO:0007568 9.16 FOS MPO
2 response to lipopolysaccharide GO:0032496 8.96 FOS MPO
3 response to mechanical stimulus GO:0009612 8.62 FOS MPO

Molecular functions related to Acute Pericementitis according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 chromatin binding GO:0003682 8.62 FOS MPO

Sources for Acute Pericementitis

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
17 EFO
18 ExPASy
20 FMA
29 GO
30 GTR
31 HGMD
32 HMDB
33 HPO
34 ICD10
35 ICD10 via Orphanet
36 ICD9CM
37 IUPHAR
38 KEGG
39 LifeMap
41 LOVD
43 MedGen
45 MeSH
46 MESH via Orphanet
47 MGI
50 NCI
51 NCIt
52 NDF-RT
55 NINDS
56 Novoseek
58 OMIM
59 OMIM via Orphanet
63 PubMed
65 QIAGEN
70 SNOMED-CT via HPO
71 SNOMED-CT via Orphanet
72 TGDB
73 Tocris
74 UMLS
75 UMLS via Orphanet
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