MCID: ACT062
MIFTS: 26

Acute Pericementitis

Categories: Gastrointestinal diseases, Oral diseases

Aliases & Classifications for Acute Pericementitis

MalaCards integrated aliases for Acute Pericementitis:

Name: Acute Pericementitis 12 15
Acute Periodontitis 12 73

Classifications:



External Ids:

Disease Ontology 12 DOID:10423
ICD9CM 35 523.3 523.33
NCIt 50 C34354
ICD10 33 K05.2
UMLS 73 C0001342

Summaries for Acute Pericementitis

MalaCards based summary : Acute Pericementitis, also known as acute periodontitis, is related to aggressive periodontitis and periodontitis. An important gene associated with Acute Pericementitis is FOS (Fos Proto-Oncogene, AP-1 Transcription Factor Subunit), and among its related pathways/superpathways are Endometrial cancer and Immune response IL-23 signaling pathway. The drugs Amoxicillin and Estradiol have been mentioned in the context of this disorder. Affiliated tissues include bone, b cells and testes.

Related Diseases for Acute Pericementitis

Diseases related to Acute Pericementitis via text searches within MalaCards or GeneCards Suite gene sharing:

# Related Disease Score Top Affiliating Genes
1 aggressive periodontitis 10.1
2 periodontitis 9.7
3 periodontal disease 9.6

Comorbidity relations with Acute Pericementitis via Phenotypic Disease Network (PDN):


Dental Caries

Symptoms & Phenotypes for Acute Pericementitis

Drugs & Therapeutics for Acute Pericementitis

Drugs for Acute Pericementitis (from DrugBank, HMDB, Dgidb, PharmGKB, IUPHAR, NovoSeek, BitterDB):

(show top 50) (show all 63)
# Name Status Phase Clinical Trials Cas Number PubChem Id
1
Amoxicillin Approved, Vet_approved Phase 4,Phase 2,Phase 3,Not Applicable 26787-78-0 33613
2
Estradiol Approved, Investigational, Vet_approved Phase 4 50-28-2 5757
3 Estradiol valerate Approved, Investigational, Vet_approved Phase 4 979-32-8
4
Ethinyl Estradiol Approved Phase 4 57-63-6 5991
5
Metronidazole Approved Phase 4,Phase 2,Phase 3,Not Applicable 443-48-1 4173
6
Moxifloxacin Approved, Investigational Phase 4 354812-41-2, 151096-09-2 152946
7
Norgestimate Approved, Investigational Phase 4 35189-28-7 6540478
8
Polyestradiol phosphate Approved Phase 4 28014-46-2
9
Chlorhexidine Approved, Vet_approved Phase 4 55-56-1 9552079 2713
10 Anesthetics Phase 4
11 Anti-Bacterial Agents Phase 4,Phase 2,Phase 3,Not Applicable
12 Antibiotics, Antitubercular Phase 4,Phase 2,Phase 3,Not Applicable
13 Anti-Infective Agents Phase 4,Phase 2,Phase 3,Not Applicable
14 Antiparasitic Agents Phase 4,Phase 2,Phase 3
15 Antiprotozoal Agents Phase 4,Phase 2,Phase 3
16 Contraceptive Agents Phase 4
17 Contraceptives, Oral Phase 4
18 Contraceptives, Oral, Combined Phase 4
19 Estradiol 17 beta-cypionate Phase 4
20 Estradiol 3-benzoate Phase 4
21 Fluoroquinolones Phase 4
22 Norgestimate, ethinyl estradiol drug combination Phase 4
23 Nucleic Acid Synthesis Inhibitors Phase 4
24 Topoisomerase Inhibitors Phase 4
25 Chlorhexidine gluconate Phase 4
26 Anesthetics, Local Phase 4
27
Clarithromycin Approved Phase 2, Phase 3,Phase 3,Not Applicable 81103-11-9 84029
28
Aspirin Approved, Vet_approved Phase 2, Phase 3,Phase 3 50-78-2 2244
29 Cytochrome P-450 CYP3A Inhibitors Phase 2, Phase 3,Phase 3,Not Applicable
30 Cytochrome P-450 Enzyme Inhibitors Phase 2, Phase 3,Phase 3,Not Applicable
31 Analgesics Phase 2, Phase 3,Phase 3
32 Analgesics, Non-Narcotic Phase 2, Phase 3,Phase 3
33 Anti-Inflammatory Agents Phase 2, Phase 3,Phase 3
34 Anti-Inflammatory Agents, Non-Steroidal Phase 2, Phase 3,Phase 3
35 Antipyretics Phase 2, Phase 3,Phase 3
36 Antirheumatic Agents Phase 2, Phase 3,Phase 3
37 Cyclooxygenase Inhibitors Phase 2, Phase 3,Phase 3
38 Fibrinolytic Agents Phase 2, Phase 3,Phase 3
39 Peripheral Nervous System Agents Phase 2, Phase 3,Phase 3
40 Platelet Aggregation Inhibitors Phase 2, Phase 3,Phase 3
41 Omega 3 Fatty Acid Nutraceutical Phase 2, Phase 3,Phase 3
42
Nitric Oxide Approved 10102-43-9 145068 160954
43
Ergocalciferol Approved, Nutraceutical 50-14-6 5280793
44
Vitamin D Approved, Nutraceutical, Vet_approved 1406-16-2
45 Bone Density Conservation Agents
46 Dihydroxycholecalciferols
47 Ergocalciferols
48 Micronutrients
49 Trace Elements
50 Vitamins

Interventional clinical trials:

(show all 42)
# Name Status NCT ID Phase Drugs
1 Efficacy of Three Antibiotic Protocols for Aggressive Periodontitis Treatment Unknown status NCT02839421 Phase 4 Scaling and Root Planing combined with moxifloxacin
2 Adjunctive Systemic Administration of Moxifloxacin in the Treatment of Aggressive Periodontitis Completed NCT02125812 Phase 4
3 Evaluation of Efficacy of Full-mouth Disinfection in Generalized Aggressive Periodontitis Patients Completed NCT02466646 Phase 4 Klorhex® Gel, rinse and sprey
4 Treatment of Aggressive Periodontitis With Repeated Adjunctive Antimicrobial Photodynamic Therapy Completed NCT02049008 Phase 4
5 Host Modulatory Effects of β-glucan on Localized Aggressive Periodontitis Completed NCT02402296 Phase 4 β-1,3/1,6-D-glucan
6 Alternative Antibiotic Regime in the Treatment of GAgP Completed NCT02223702 Phase 4 Amoxicillin;Metronidazole;Moxifloxacin
7 Enamel Matrix Proteins in the Treatment of Intrabony Defects in Patients With Aggressive and Chronic Periodontitis Recruiting NCT03025204 Phase 4
8 Two Different Antibiotic Agents to Treat Generalized Aggressive Periodontitis Completed NCT02969928 Phase 2, Phase 3 Clarithromycin;Amoxicillin;Metronidazole
9 Periodontal Debridement Associated With Systemic Antibiotics and Single/Repeated PDT to Treat Aggressive Periodontitis Completed NCT03132714 Phase 2, Phase 3 Amoxicillin 500mg;Metronidazole 400mg;Clarithromycin 500mg
10 Omega-3 Fatty Acids Plus Low-dose Aspirin Daily Supplementation in Surgical Therapy to Treat Aggressive Periodontitis Recruiting NCT03093207 Phase 2, Phase 3 Aspirin
11 Omega-3 Plus Low-dose Aspirin Daily Supplementation in Non-surgical Therapy to Treat Aggressive Periodontitis Recruiting NCT03093246 Phase 2, Phase 3 Aspirin
12 The Affect of Orthodontic Treatment on the Periodontal Status of Patients With Aggressive Periodontitis Unknown status NCT01510808
13 Polymorphonuclear Cells' Sensitivity to Aggregatibacter Actinomycetemcomitans Bacteria in Patients With Aggressive Periodontitis Unknown status NCT02010307 Not Applicable
14 Chronic Presence of Epstein Barr Virus in Epithelial Cells From Gingiva is Associated With Periodontitis Unknown status NCT01246596 Not Applicable
15 Immunolocalization of 1,25,Dihydroxyvitamin D3 in Aggressive Periodontitis Patients Completed NCT02282800
16 Gene Expression Profiles in Generalized Aggressive Periodontitis: A Gene Network-based Microarray Analysis Completed NCT02327533
17 Effects of Smoking on Non-surgical Periodontal Therapy in Generalized Aggressive Periodontitis Completed NCT03512938 Not Applicable
18 Effects Of Adjunctive Photodynamic Therapy To Non-Surgical Periodontal Treatment In Patients With Generalized Aggressive Periodontitis Completed NCT03412331 Not Applicable
19 Gingival Crevicular Fluid Levels Of Monocyte Chemoattractant Protein-1 Completed NCT02927704
20 Frequency Of MCP-1 And CCR2 Gene Polymorphisms And Its Effect On Gene Expression In Patients With AgP Completed NCT02817568
21 Effects of Er,Cr:YSGG, Diode Lasers on GCF Cytokines Levels Completed NCT03034824 Not Applicable
22 Clarithromycin as Adjuvant to Periodontal Debridement Completed NCT02829983 Not Applicable Clarithromycin;Placebo
23 Smoking Influence on Apoptosis in Periodontitis Completed NCT02111005
24 Nonsurgical Periodontal Treatment Associated or Not With Systemic Antibiotics and Photodynamic Therapy Completed NCT03142776 Not Applicable systemic clarithromycin
25 Effect of Surgical Therapy on RANKL/OPG (Osteoprotegerin) System Completed NCT02190773
26 Estimation of Pentrexin-3 Levels in GCF and Saliva of Patients With Periodontal Disease Completed NCT03128502
27 Nitro-oxidative Stress in Periodontitis Completed NCT02127203
28 TNF-α/HIF-1α/VEGF Pathway in Periodontal Diseases Completed NCT03558906
29 Active Matrix Metalloproteinase-8 (aMMP-8) Chair-side Test in Different Periodontal Disease Completed NCT03527901
30 The Importance of Periostin in Periodontal Health and Disease Completed NCT01180920
31 Gingival Bleeding and Von Willebrand Disease Typ 2 and 3 Completed NCT03078595
32 Perforated Collagen Membrane With Nanohydroxyapatite for Intrabony Defects Completed NCT03399279 Not Applicable
33 Immediate Implant Placement in Aggressive Periodontitis Recruiting NCT03218228 Not Applicable
34 Mechanisms and Treatment Response of Aggressive Periodontitis in Children Recruiting NCT01330719 Not Applicable
35 Subgingival Microbiome Following Mechanical Treatment and it's Effect on Peri-implant Sub-mucosa in Aggressive Periodontitis Patients Recruiting NCT03090282
36 EMD for Treatment of Proximal Class-II Furcation Involvements Recruiting NCT03320135 Not Applicable
37 B Cell Functions in Periodontitis Recruiting NCT02833285
38 Interaction Between Immune Cells and Bacteria Associated With Periodontitis Recruiting NCT03225950
39 Comparison Between Surgical Access and Repeated Applications of APDT Active, not recruiting NCT03140059 Not Applicable
40 Long-term Results After Systematic Periodontal Therapy Enrolling by invitation NCT03048045
41 Clinical and Radiographic Evaluation of Guided Tissue Regeneration With Radiation-sterilized Allogenic Bone Grafts or Xenogenic Grafts for the Treatment of Intrabony Defects in Aggressive Periodontitis Not yet recruiting NCT03340012 Not Applicable
42 Analysis of Osteoimmune Interactions Linking Inflammation and Bone Destruction in Aggressive Periodontitis Terminated NCT01993368 Not Applicable

Search NIH Clinical Center for Acute Pericementitis

Genetic Tests for Acute Pericementitis

Anatomical Context for Acute Pericementitis

MalaCards organs/tissues related to Acute Pericementitis:

41
Bone, B Cells, Testes, Monocytes

Publications for Acute Pericementitis

Articles related to Acute Pericementitis:

# Title Authors Year
1
Nanotechnology in Phytotherapy: Antiinflammatory Effect of a Nanostructured Thymol Gel from Lippia sidoides in Acute Periodontitis in Rats. ( 26553130 )
2015
2
Aggressive and acute periodontal diseases. ( 24738583 )
2014

Variations for Acute Pericementitis

Expression for Acute Pericementitis

Search GEO for disease gene expression data for Acute Pericementitis.

Pathways for Acute Pericementitis

GO Terms for Acute Pericementitis

Biological processes related to Acute Pericementitis according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 response to lipopolysaccharide GO:0032496 9.16 FOS MPO
2 aging GO:0007568 8.96 FOS MPO
3 response to mechanical stimulus GO:0009612 8.62 FOS MPO

Molecular functions related to Acute Pericementitis according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 chromatin binding GO:0003682 8.62 FOS MPO

Sources for Acute Pericementitis

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
17 ExPASy
19 FMA
28 GO
29 GTR
30 HGMD
31 HMDB
32 HPO
33 ICD10
34 ICD10 via Orphanet
35 ICD9CM
36 IUPHAR
37 KEGG
38 LifeMap
40 LOVD
42 MedGen
44 MeSH
45 MESH via Orphanet
46 MGI
49 NCI
50 NCIt
51 NDF-RT
54 NINDS
55 Novoseek
57 OMIM
58 OMIM via Orphanet
62 PubMed
64 QIAGEN
69 SNOMED-CT via HPO
70 SNOMED-CT via Orphanet
71 TGDB
72 Tocris
73 UMLS
74 UMLS via Orphanet
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