Acute Pericementitis

Categories: Gastrointestinal diseases, Oral diseases

Aliases & Classifications for Acute Pericementitis

MalaCards integrated aliases for Acute Pericementitis:

Name: Acute Pericementitis 12 15
Acute Periodontitis 12 74


External Ids:

Disease Ontology 12 DOID:10423
ICD9CM 36 523.3 523.33
NCIt 51 C34354
SNOMED-CT 69 21638000
ICD10 34 K05.2
UMLS 74 C0001342

Summaries for Acute Pericementitis

MalaCards based summary : Acute Pericementitis, also known as acute periodontitis, is related to aggressive periodontitis and periodontal disease. An important gene associated with Acute Pericementitis is FOS (Fos Proto-Oncogene, AP-1 Transcription Factor Subunit), and among its related pathways/superpathways are Regulation of TP53 Activity and Endometrial cancer. The drugs Estradiol and Metronidazole have been mentioned in the context of this disorder. Affiliated tissues include bone, testes and b cells.

Related Diseases for Acute Pericementitis

Diseases related to Acute Pericementitis via text searches within MalaCards or GeneCards Suite gene sharing:

# Related Disease Score Top Affiliating Genes
1 aggressive periodontitis 10.3
2 periodontal disease 10.1
3 periodontitis 10.1

Comorbidity relations with Acute Pericementitis via Phenotypic Disease Network (PDN):

Dental Caries

Symptoms & Phenotypes for Acute Pericementitis

Drugs & Therapeutics for Acute Pericementitis

Drugs for Acute Pericementitis (from DrugBank, HMDB, Dgidb, PharmGKB, IUPHAR, NovoSeek, BitterDB):

(show top 50) (show all 79)
# Name Status Phase Clinical Trials Cas Number PubChem Id
Estradiol Approved, Investigational, Vet_approved Phase 4 50-28-2 5757
Metronidazole Approved Phase 4,Phase 2,Phase 3,Phase 1,Not Applicable 443-48-1 4173
Moxifloxacin Approved, Investigational Phase 4 354812-41-2, 151096-09-2 152946
Norgestimate Approved, Investigational Phase 4 35189-28-7 6540478
Polyestradiol phosphate Approved Phase 4 28014-46-2
Ethinyl Estradiol Approved Phase 4 57-63-6 5991
Amoxicillin Approved, Vet_approved Phase 4,Phase 2,Phase 3,Phase 1,Not Applicable 26787-78-0 33613
Chlorhexidine Approved, Vet_approved Phase 4 55-56-1 2713 9552079
Triclosan Approved, Investigational Phase 4 3380-34-5 5564
10 sodium fluoride Approved Phase 4 7681-49-4
11 Antiparasitic Agents Phase 4,Phase 2,Phase 3,Phase 1
12 Contraceptives, Oral Phase 4
13 Anesthetics Phase 4,Not Applicable
14 Estradiol 17 beta-cypionate Phase 4
15 Antiprotozoal Agents Phase 4,Phase 2,Phase 3,Phase 1
16 Contraceptives, Oral, Combined Phase 4
17 Contraceptive Agents Phase 4
18 Anti-Infective Agents Phase 4,Phase 2,Phase 3,Phase 1,Not Applicable
19 Topoisomerase Inhibitors Phase 4
20 Norgestimate, ethinyl estradiol drug combination Phase 4
21 Anti-Bacterial Agents Phase 4,Phase 2,Phase 3,Phase 1,Not Applicable
22 Antibiotics, Antitubercular Phase 4,Phase 2,Phase 3,Phase 1,Not Applicable
23 Estradiol 3-benzoate Phase 4
24 Chlorhexidine gluconate Phase 4
25 Listerine Phase 4
26 Anti-Infective Agents, Local Phase 4
27 Fluorides Phase 4
28 Hypolipidemic Agents Phase 4
29 Cariostatic Agents Phase 4
30 Antimetabolites Phase 4
31 Lipid Regulating Agents Phase 4
32 Protective Agents Phase 4
33 Anesthetics, Local Phase 4
Aspirin Approved, Vet_approved Phase 2, Phase 3,Phase 3 50-78-2 2244
Clarithromycin Approved Phase 2, Phase 3,Phase 3,Not Applicable 81103-11-9 84029
36 Antirheumatic Agents Phase 2, Phase 3,Phase 3
37 Platelet Aggregation Inhibitors Phase 2, Phase 3,Phase 3
38 Analgesics, Non-Narcotic Phase 2, Phase 3,Phase 3
39 Anti-Inflammatory Agents, Non-Steroidal Phase 2, Phase 3,Phase 3
40 Analgesics Phase 2, Phase 3,Phase 3
41 Peripheral Nervous System Agents Phase 2, Phase 3,Phase 3
42 Omega 3 Fatty Acid Phase 2, Phase 3,Phase 3
43 Fibrinolytic Agents Phase 2, Phase 3,Phase 3
44 Anti-Inflammatory Agents Phase 2, Phase 3,Phase 3
45 Cyclooxygenase Inhibitors Phase 2, Phase 3,Phase 3
46 Antipyretics Phase 2, Phase 3,Phase 3
47 Cytochrome P-450 Enzyme Inhibitors Phase 2, Phase 3,Phase 3,Not Applicable
48 Cytochrome P-450 CYP3A Inhibitors Phase 2, Phase 3,Phase 3,Not Applicable
Doxycycline Approved, Investigational, Vet_approved Phase 1, Phase 2 564-25-0 54671203
50 Antimalarials Phase 1, Phase 2

Interventional clinical trials:

(show all 48)
# Name Status NCT ID Phase Drugs
1 Efficacy of Three Antibiotic Protocols for Aggressive Periodontitis Treatment Unknown status NCT02839421 Phase 4 Scaling and Root Planing combined with moxifloxacin
2 Adjunctive Systemic Administration of Moxifloxacin in the Treatment of Aggressive Periodontitis Completed NCT02125812 Phase 4
3 Evaluation of Efficacy of Full-mouth Disinfection in Generalized Aggressive Periodontitis Patients Completed NCT02466646 Phase 4 Klorhex® Gel, rinse and sprey
4 Amoxicillin and Metronidazole in Association With Non-surgical Therapy in Aggressive Periodontitis Treatment Completed NCT03933501 Phase 4 amoxicillin and metronidazole;Placebos
5 Treatment of Aggressive Periodontitis With Repeated Adjunctive Antimicrobial Photodynamic Therapy Completed NCT02049008 Phase 4
6 Triclosan as Adjunctive Therapy in the Plaque Control in Children From Generalized Aggressive Periodontitis Families. Completed NCT03642353 Phase 4 Triclosan;Placebo
7 Host Modulatory Effects of β-glucan on Localized Aggressive Periodontitis Completed NCT02402296 Phase 4 β-1,3/1,6-D-glucan
8 Alternative Antibiotic Regime in the Treatment of GAgP Completed NCT02223702 Phase 4 Amoxicillin;Metronidazole;Moxifloxacin
9 Enamel Matrix Proteins in the Treatment of Intrabony Defects in Patients With Aggressive and Chronic Periodontitis Completed NCT03025204 Phase 4
10 Omega-3 Fatty Acids Plus Low-dose Aspirin Daily Supplementation in Surgical Therapy to Treat Aggressive Periodontitis Unknown status NCT03093207 Phase 2, Phase 3 Aspirin
11 Omega-3 Plus Low-dose Aspirin Daily Supplementation in Non-surgical Therapy to Treat Aggressive Periodontitis Unknown status NCT03093246 Phase 2, Phase 3 Aspirin
12 Two Different Antibiotic Agents to Treat Generalized Aggressive Periodontitis Completed NCT02969928 Phase 2, Phase 3 Clarithromycin;Amoxicillin;Metronidazole
13 Periodontal Debridement Associated With Systemic Antibiotics and Single/Repeated PDT to Treat Aggressive Periodontitis Completed NCT03132714 Phase 2, Phase 3 Amoxicillin 500mg;Metronidazole 400mg;Clarithromycin 500mg
14 Doxycycline in the Treatment of Aggressive Periodontitis Completed NCT03727620 Phase 1, Phase 2 amoxicillin plus metronidazole;Doxycycline
15 The Affect of Orthodontic Treatment on the Periodontal Status of Patients With Aggressive Periodontitis Unknown status NCT01510808
16 Subgingival Microbiome Following Mechanical Treatment and it's Effect on Peri-implant Sub-mucosa in Aggressive Periodontitis Patients Unknown status NCT03090282
17 Polymorphonuclear Cells' Sensitivity to Aggregatibacter Actinomycetemcomitans Bacteria in Patients With Aggressive Periodontitis Unknown status NCT02010307 Not Applicable
18 Chronic Presence of Epstein Barr Virus in Epithelial Cells From Gingiva is Associated With Periodontitis Unknown status NCT01246596 Not Applicable
19 B Cell Functions in Periodontitis Unknown status NCT02833285
20 Immunolocalization of 1,25,Dihydroxyvitamin D3 in Aggressive Periodontitis Patients Completed NCT02282800
21 Gene Expression Profiles in Generalized Aggressive Periodontitis: A Gene Network-based Microarray Analysis Completed NCT02327533
22 Metagenomic and Immune-inflammatory Analysis of Individuals With Generalized Aggressive Periodontitis and Their Descendants. Completed NCT03933514
23 Effects of Smoking on Non-surgical Periodontal Therapy in Generalized Aggressive Periodontitis Completed NCT03512938 Not Applicable
24 Effects Of Adjunctive Photodynamic Therapy To Non-Surgical Periodontal Treatment In Patients With Generalized Aggressive Periodontitis Completed NCT03412331 Not Applicable
25 Gingival Crevicular Fluid Levels Of Monocyte Chemoattractant Protein-1 Completed NCT02927704
26 Frequency Of MCP-1 And CCR2 Gene Polymorphisms And Its Effect On Gene Expression In Patients With AgP Completed NCT02817568
27 Effects of Er,Cr:YSGG, Diode Lasers on GCF Cytokines Levels Completed NCT03034824 Not Applicable
28 Clarithromycin as Adjuvant to Periodontal Debridement Completed NCT02829983 Not Applicable Clarithromycin;Placebo
29 Smoking Influence on Apoptosis in Periodontitis Completed NCT02111005
30 Tissue Alterations in Aggressive and Chronic Periodontitis Completed NCT03625414
31 Nonsurgical Periodontal Treatment Associated or Not With Systemic Antibiotics and Photodynamic Therapy Completed NCT03142776 Not Applicable systemic clarithromycin
32 Effect of Surgical Therapy on RANKL/OPG (Osteoprotegerin) System Completed NCT02190773
33 Estimation of Pentrexin-3 Levels in GCF and Saliva of Patients With Periodontal Disease Completed NCT03128502
34 Clinical, Immunological and Microbiological Evaluation of Experimental Gingivitis and Peri-implant Mucositis Completed NCT03713567 Not Applicable
35 Nitro-oxidative Stress in Periodontitis Completed NCT02127203
36 TNF-α/HIF-1α/VEGF Pathway in Periodontal Diseases Completed NCT03558906
37 Active Matrix Metalloproteinase-8 (aMMP-8) Chair-side Test in Different Periodontal Disease Completed NCT03527901
38 The Importance of Periostin in Periodontal Health and Disease Completed NCT01180920
39 Gingival Bleeding and Von Willebrand Disease Typ 2 and 3 Completed NCT03078595
40 Perforated Collagen Membrane With Nanohydroxyapatite for Intrabony Defects Completed NCT03399279 Not Applicable
41 Immediate Implant Placement in Aggressive Periodontitis Recruiting NCT03218228 Not Applicable
42 EMD for Treatment of Proximal Class-II Furcation Involvements Recruiting NCT03320135 Not Applicable
43 Mechanisms and Treatment Response of Aggressive Periodontitis in Children Active, not recruiting NCT01330719 Not Applicable
44 Comparison Between Surgical Access and Repeated Applications of APDT Active, not recruiting NCT03140059 Not Applicable
45 Interaction Between Immune Cells and Bacteria Associated With Periodontitis Active, not recruiting NCT03225950
46 Long-term Results After Systematic Periodontal Therapy Enrolling by invitation NCT03048045
47 Clinical and Radiographic Evaluation of Guided Tissue Regeneration With Radiation-sterilized Allogenic Bone Grafts or Xenogenic Grafts for the Treatment of Intrabony Defects in Aggressive Periodontitis Not yet recruiting NCT03340012 Not Applicable
48 Analysis of Osteoimmune Interactions Linking Inflammation and Bone Destruction in Aggressive Periodontitis Terminated NCT01993368 Not Applicable

Search NIH Clinical Center for Acute Pericementitis

Genetic Tests for Acute Pericementitis

Anatomical Context for Acute Pericementitis

MalaCards organs/tissues related to Acute Pericementitis:

Bone, Testes, B Cells, Monocytes, Brain

Publications for Acute Pericementitis

Articles related to Acute Pericementitis:

# Title Authors Year
Nanotechnology in Phytotherapy: Antiinflammatory Effect of a Nanostructured Thymol Gel from Lippia sidoides in Acute Periodontitis in Rats. ( 26553130 )
Selection of an optimal treatment method for acute periodontitis disease. ( 20703669 )
Anti-inflammatory effect of alpha, beta-Amyrin, a pentacyclic triterpene from Protium heptaphyllum in rat model of acute periodontitis. ( 18046512 )
New role of the trigeminal nerve as a neuronal pathway signaling brain in acute periodontitis: participation of local prostaglandins. ( 16902799 )
A simple surgical treatment for acute periodontitis in the dog. ( 1041095 )
[A method of local anesthetization in the treatment of acute periodontitis]. ( 21012726 )

Variations for Acute Pericementitis

Expression for Acute Pericementitis

Search GEO for disease gene expression data for Acute Pericementitis.

Pathways for Acute Pericementitis

GO Terms for Acute Pericementitis

Biological processes related to Acute Pericementitis according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 aging GO:0007568 9.16 FOS MPO
2 response to lipopolysaccharide GO:0032496 8.96 FOS MPO
3 response to mechanical stimulus GO:0009612 8.62 FOS MPO

Molecular functions related to Acute Pericementitis according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 chromatin binding GO:0003682 8.62 FOS MPO

Sources for Acute Pericementitis

9 Cosmic
10 dbSNP
11 DGIdb
17 EFO
18 ExPASy
20 FMA
29 GO
30 GTR
33 HPO
34 ICD10
35 ICD10 via Orphanet
39 LifeMap
43 MedGen
45 MeSH
46 MESH via Orphanet
47 MGI
50 NCI
51 NCIt
56 Novoseek
59 OMIM via Orphanet
63 PubMed
71 SNOMED-CT via Orphanet
73 Tocris
75 UMLS via Orphanet
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