MCID: ACT078
MIFTS: 48

Acute Porphyria

Categories: Metabolic diseases, Rare diseases

Aliases & Classifications for Acute Porphyria

MalaCards integrated aliases for Acute Porphyria:

Name: Acute Porphyria 12 6 15
Porphyrias, Hepatic 45 74
Hepatic Porphyria 12 38
Acute Intermittent Porphyria 74

Classifications:



External Ids:

Disease Ontology 12 DOID:3133
KEGG 38 H00202
MeSH 45 D017094
SNOMED-CT 69 55056006

Summaries for Acute Porphyria

Disease Ontology : 12 A porphyria that has symptom abdominal pain, has symptom neuropathy, has symptom autonomic instability and has symptom psychosis.

MalaCards based summary : Acute Porphyria, also known as porphyrias, hepatic, is related to protoporphyria, erythropoietic, 1 and porphyria, acute intermittent, and has symptoms including abdominal pain, psychosis and neuropathy. An important gene associated with Acute Porphyria is HMBS (Hydroxymethylbilane Synthase), and among its related pathways/superpathways are Porphyrin and chlorophyll metabolism and Metabolism. The drugs Deferasirox and Iron have been mentioned in the context of this disorder. Affiliated tissues include liver, bone and testes, and related phenotypes are homeostasis/metabolism and liver/biliary system

Related Diseases for Acute Porphyria

Diseases in the Porphyria family:

Acute Porphyria

Diseases related to Acute Porphyria via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50) (show all 56)
# Related Disease Score Top Affiliating Genes
1 protoporphyria, erythropoietic, 1 30.5 ALAD ALAS2 CPOX FECH HMBS PPOX
2 porphyria, acute intermittent 30.5 ALAD ALAS1 CPOX FECH HMBS PPOX
3 porphyria variegata 30.3 ALAD CPOX FECH HFE HMBS PPOX
4 porphyria cutanea tarda 30.0 ALAD ALAS1 CPOX FECH HFE HMBS
5 porphyria 29.9 ALAD ALAS1 ALAS2 CPOX FECH HFE
6 coproporphyria, hereditary 29.5 ALAD ALAS1 ALAS2 CPOX FECH HMBS
7 chester porphyria 11.6
8 neuropathy 10.1
9 x-linked protoporphyria 10.0 ALAS2 FECH
10 hepatitis 10.0
11 porphyria cutanea tarda, type i 10.0 HFE UROD
12 porphyria, acute hepatic 10.0
13 peripheral nervous system disease 10.0
14 familial porphyria cutanea tarda 10.0 HFE UROD
15 epilepsy 9.9
16 hepatitis c 9.9
17 focal epilepsy 9.9
18 siderosis 9.9 HFE UROD
19 hyperphenylalaninemia due to dehydratase deficiency 9.9
20 encephalopathy 9.9
21 hemochromatosis type 2 9.9 ALAS2 HFE
22 rhizomelic chondrodysplasia punctata, type 2 9.8 HFE UROD
23 pfeiffer syndrome 9.8
24 antipyrine metabolism 9.8
25 breast cancer 9.8
26 systemic lupus erythematosus 9.8
27 hepatitis c virus 9.8
28 liver disease 9.8
29 typhoidal tularemia 9.8
30 viral hepatitis 9.8
31 tularemia 9.8
32 lupus erythematosus 9.8
33 lichen planus 9.8
34 fanconi syndrome 9.8 ALAD HNF4A
35 hepatocellular carcinoma 9.8
36 chiari malformation type ii 9.8
37 myocardial infarction 9.8
38 acute myocardial infarction 9.8
39 brucellosis 9.8
40 cerebral atherosclerosis 9.8
41 guillain-barre syndrome 9.8
42 polyneuropathy 9.8
43 pericarditis 9.8
44 status epilepticus 9.8
45 constipation 9.8
46 schizoaffective disorder 9.8
47 myocarditis 9.8
48 appendicitis 9.8
49 binswanger's disease 9.8
50 chiari malformation 9.8

Graphical network of the top 20 diseases related to Acute Porphyria:



Diseases related to Acute Porphyria

Symptoms & Phenotypes for Acute Porphyria

Symptoms:

12
  • abdominal pain
  • psychosis
  • neuropathy
  • autonomic instability

UMLS symptoms related to Acute Porphyria:


seizures, constipation, vomiting, abdominal pain, diarrhea, dysuria, nausea, weakness

MGI Mouse Phenotypes related to Acute Porphyria:

47
# Description MGI Source Accession Score Top Affiliating Genes
1 homeostasis/metabolism MP:0005376 9.9 ALAS2 CPOX FECH GLUL HFE HMBS
2 liver/biliary system MP:0005370 9.5 FECH GLUL HFE HNF4A NR1I2 UROD
3 mortality/aging MP:0010768 9.44 ALAS1 ALAS2 CPOX FECH GLUL HFE

Drugs & Therapeutics for Acute Porphyria

Drugs for Acute Porphyria (from DrugBank, HMDB, Dgidb, PharmGKB, IUPHAR, NovoSeek, BitterDB):

(show top 50) (show all 79)
# Name Status Phase Clinical Trials Cas Number PubChem Id
1
Deferasirox Approved, Investigational Phase 3,Phase 2 201530-41-8 5493381
2
Iron Approved, Experimental Phase 3,Phase 2,Not Applicable 7439-89-6, 15438-31-0 27284 23925
3
Colestipol Approved Phase 2, Phase 3 26658-42-4
4
Afamelanotide Experimental, Investigational Phase 3,Phase 2 75921-69-6
5 Hormones, Hormone Substitutes, and Hormone Antagonists Phase 3,Phase 2,Not Applicable
6 Hormone Antagonists Phase 3,Phase 2,Not Applicable
7 Hormones Phase 3,Phase 2,Not Applicable
8 Dermatologic Agents Phase 3,Phase 2,Not Applicable
9 alpha-MSH Phase 3,Phase 2 581-05-5
10 Iron Chelating Agents Phase 3,Phase 2
11 Chelating Agents Phase 3,Phase 2
12 cysteine Phase 3,Not Applicable
13 Lipid Regulating Agents Phase 2, Phase 3,Not Applicable
14 Antimetabolites Phase 2, Phase 3,Not Applicable
15 Hypolipidemic Agents Phase 2, Phase 3,Not Applicable
16
Hydroxychloroquine Approved Phase 2 118-42-3 3652
17
Ledipasvir Approved Phase 2 1256388-51-8 67505836
18
Sofosbuvir Approved Phase 2 1190307-88-0 45375808
19 Tin mesoporphyrin Phase 1, Phase 2,Phase 2
20
Tin Phase 1, Phase 2,Phase 2 7440-31-5
21 Antiparasitic Agents Phase 2
22 Antiprotozoal Agents Phase 2
23 Anti-Infective Agents Phase 2,Not Applicable
24 Antimalarials Phase 2
25 Antirheumatic Agents Phase 2
26 Antiviral Agents Phase 2
27 Ledipasvir, sofosbuvir drug combination Phase 2
28
Guaifenesin Approved, Investigational, Vet_approved Phase 1 93-14-1 3516
29
Midazolam Approved, Illicit Phase 1 59467-70-8 4192
30
Dextromethorphan Approved Phase 1 125-71-3 5362449 5360696
31
Omeprazole Approved, Investigational, Vet_approved Phase 1 73590-58-6 4594
32
Caffeine Approved Phase 1 58-08-2 2519
33
Losartan Approved Phase 1 114798-26-4 3961
34
Chlorpromazine Approved, Investigational, Vet_approved Phase 1 50-53-3 2726
35
Dopamine Approved Phase 1 62-31-7, 51-61-6 681
36
Pentoxifylline Approved, Investigational Phase 1 6493-05-6 4740
37
Tocopherol Approved, Investigational Phase 1 1406-66-2 14986
38
Vitamin E Approved, Nutraceutical, Vet_approved Phase 1 59-02-9 14985
39 Tocotrienol Investigational Phase 1 6829-55-6
40 Liver Extracts Phase 1
41 Chlorpheniramine, phenylpropanolamine drug combination Phase 1
42 Excitatory Amino Acids Phase 1
43 Gastrointestinal Agents Phase 1
44 Neurotransmitter Agents Phase 1
45 Antacids Phase 1
46 Excitatory Amino Acid Antagonists Phase 1
47 Anti-Ulcer Agents Phase 1
48 Antitussive Agents Phase 1
49 Respiratory System Agents Phase 1
50 Proton Pump Inhibitors Phase 1

Interventional clinical trials:

(show all 45)
# Name Status NCT ID Phase Drugs
1 Phase III Confirmatory Study in Erythropoietic Protoporphyria Unknown status NCT01605136 Phase 3 Afamelanotide;Placebo
2 Porphozym in the Treatment of Acute Attacks in AIP Completed NCT00418795 Phase 2, Phase 3 recombinant human porphobilinogen deaminase (Porphozym)
3 Pilot Trial of Deferasirox in the Treatment of Porphyria Cutanea Tarda Completed NCT00599326 Phase 3 Deferasirox
4 Phase III Confirmatory Study in Erythropoietic Protoporphyria (EPP) Completed NCT00979745 Phase 3 Afamelanotide;Placebo
5 Phase III Study of L-Cysteine in Patients With Erythropoietic Protoporphyria Completed NCT00004940 Phase 3 cysteine hydrochloride
6 Sorbent Therapy of the Cutaneous Porphyrias Completed NCT01422915 Phase 2, Phase 3 Colestipol
7 ENVISION: A Study to Evaluate the Efficacy and Safety of Givosiran (ALN-AS1) in Patients With Acute Hepatic Porphyrias (AHP) Active, not recruiting NCT03338816 Phase 3 Givosiran;Placebo
8 Heme Arginate in Cardiac Surgery Patients Unknown status NCT02142699 Phase 2 Heme arginate
9 Safety and Efficacy of Oral Deferasirox in Patients With Porphyria Cutanea Tarda Unknown status NCT01284946 Phase 2 Exjade
10 Phase I/II Study of Heme Arginate and Tin Mesoporphyrin for Acute Porphyria Completed NCT00004789 Phase 1, Phase 2 heme arginate;tin mesoporphyrin
11 Studies in Porphyria III: Heme and Tin Mesoporphyrin in Acute Porphyrias Completed NCT00004396 Phase 2 heme arginate;tin mesoporphyrin
12 Phase II Confirmatory Study in Erythropoietic Protoporphyria (EPP) Completed NCT01097044 Phase 2 Afamelanotide;Placebo
13 Controlled Trial of Panhematin in Treatment of Acute Attacks of Porphyria Recruiting NCT02180412 Phase 2
14 Panhematin for Prevention of Acute Attacks of Porphyria Recruiting NCT02922413 Phase 2
15 Hydroxychloroquine and Phlebotomy for Treating Porphyria Cutanea Tarda Recruiting NCT01573754 Phase 2 Hydroxychloroquine
16 Harvoni Treatment Porphyria Cutanea Tarda Recruiting NCT03118674 Phase 2 Harvoni
17 A Study to Evaluate Long-term Safety and Clinical Activity of Givosiran (ALN-AS1) in Patient With Acute Intermittent Porphyria (AIP) Active, not recruiting NCT02949830 Phase 1, Phase 2 givosiran (ALN-AS1)
18 Study to Evaluate Efficacy, Safety, and Tolerability of MT‑7117 in Subjects With Erythropoietic Protoporphyria Active, not recruiting NCT03520036 Phase 2 MT-7117 low dose;MT-7117 high dose;Placebo
19 Phase I Gene Therapy Clinical Trial Using the Vector rAAV2/5-PBGD for the Treatment of Acute Intermittent Porphyria Completed NCT02082860 Phase 1
20 A Study to Investigate the Interaction Between Givosiran and a 5-probe Drug Cocktail in Patients With Acute Intermittent Porphyria (AIP) Completed NCT03505853 Phase 1 Givosiran;5-probe cocktail
21 A Phase 1 Study of Givosiran (ALN-AS1) in Patients With Acute Intermittent Porphyria (AIP) Completed NCT02452372 Phase 1 givosiran (ALN-AS1);Sterile Normal Saline (0.9% NaCl)
22 Phase I Study of Heme Arginate With or Without Tin Mesoporphyrin in Patients With Acute Attacks of Porphyria Completed NCT00004398 Phase 1 heme arginate;tin mesoporphyrin
23 Hemin in Healthy Subjects Completed NCT00882804 Phase 1 Hemin infusion;placebo infusion
24 Assessment of Intra-subject Variability in the Bioavailability of Chlorpromazine Hydrochloride Completed NCT02943213 Phase 1 Chlorpromazine Hydrochloride
25 PentoxIfylline and Tocopherol for the Treatment of Post-radiotherapy Fibrosis in Head and Neck Cancer Patients Not yet recruiting NCT03723291 Phase 1
26 Does Exercise and Heat Increase the Lightsensibility in Patients With Erythropoietic Protoporphyria Unknown status NCT00206869 Not Applicable
27 Clinical Diagnosis of Acute Porphyria Completed NCT01568554
28 Observational Study of Acute Intermittent Porphyria Patients Completed NCT02076763
29 Study of Nutritional Factors in Porphyria Completed NCT00004788
30 Studies in Porphyria IV: Gonadotropin-Releasing Hormone (GnRH) Analogues for Prevention of Cyclic Attacks Completed NCT00004330 Not Applicable luteinizing hormone-releasing factor
31 Risk Factors of Porphyria Cutanea Tarda (PCT) Completed NCT00213772
32 Study of the Pathogenesis of Porphyria Cutanea Tarda Completed NCT00005103
33 Light Exposure Patterns and Symptoms Among Patients With Erythropoietic Protoporphyria Completed NCT03682731
34 Study of Cysteine Hydrochloride for Erythropoietic Protoporphyria Completed NCT00004831 Not Applicable cysteine hydrochloride
35 Study to Describe the Actual Situation of Hepatitis C Treatment in Brazil Completed NCT02773394
36 Longitudinal Study of the Porphyrias Recruiting NCT01561157
37 Evidence-based Assessment of Medication Sensitivity in Acute Hepatic Porphyria Recruiting NCT03906214
38 EXPLORE: A Natural History Study of Acute Hepatic Porphyria (AHP) Recruiting NCT02240784
39 Oral Iron for Erythropoietic Protoporphyrias Recruiting NCT02979249 Not Applicable Oral Iron
40 Dental Health, Diet, Inflammation and Biomarkers in Patients With Acute Intermittent Porphyria(AIP) Active, not recruiting NCT01617642
41 Erythropoietic Protoporphyrias: Studies of the Natural History, Genotype-Phenotype Correlations, and Psychosocial Impact Active, not recruiting NCT01688895
42 Mitoferrin-1 Expression in Erythropoietic Protoporphyria (Porphyria Rare Disease Clinical Research Consortium (RDCRC)) Active, not recruiting NCT01880983
43 Acute Porphyria Biomarkers for Disease Activity Enrolling by invitation NCT02935400 Hemin
44 INSIGHT-AHP: A Study to Characterize the Prevalence of Acute Hepatic Porphyria (AHP) in Patients With Clinical Presentation and History Consistent With AHP Terminated NCT03547297
45 Effect of Isoniazid on Protoporphyrin Levels in Erythropoietic Protoporphyria Terminated NCT01550705 Not Applicable Isoniazid

Search NIH Clinical Center for Acute Porphyria

Inferred drug relations via UMLS 74 / NDF-RT 52 :


Cochrane evidence based reviews: porphyrias, hepatic

Genetic Tests for Acute Porphyria

Anatomical Context for Acute Porphyria

MalaCards organs/tissues related to Acute Porphyria:

42
Liver, Bone, Testes, Bone Marrow, Brain, Pineal, Globus Pallidus

Publications for Acute Porphyria

Articles related to Acute Porphyria:

(show top 50) (show all 271)
# Title Authors Year
1
Nonconvulsive status epilepticus secondary to acute porphyria crisis. ( 30671344 )
2019
2
Reversible encephalopathy syndrome in acute porphyria attack. ( 30871823 )
2019
3
Psychiatric Aspects of Acute Porphyria: a Comprehensive Review. ( 29392446 )
2018
4
Rapid spectrophotometric quantification of urinary porphyrins and porphobilinogen as screening tool for attacks of acute porphyria. ( 29855177 )
2018
5
An Audit of the Use of Gonadorelin Analogues to Prevent Recurrent Acute Symptoms in Patients with Acute Porphyria in the United Kingdom. ( 28220410 )
2017
6
Lead Poisoning Can Be Easily Misdiagnosed as Acute Porphyria and Nonspecific Abdominal Pain. ( 28630774 )
2017
7
Cerebral vasospasm in acute porphyria. ( 28695690 )
2017
8
Radiopharmaceuticals in Acute Porphyria. ( 27568214 )
2016
9
Acute Porphyria Presenting as Major Trauma: Case Report and Literature Review. ( 27624508 )
2016
10
Clinical and Laboratory Features of Acute Porphyria: A Study of 36 Subjects in a Chinese Tertiary Referral Center. ( 28025645 )
2016
11
Melatonin modulates drug-induced acute porphyria. ( 28959532 )
2016
12
Role of delta-aminolevulinic acid in the symptoms of acute porphyria. ( 25446301 )
2015
13
Acute porphyria in a patient with Arnold Chiari malformation. ( 25697467 )
2015
14
Audit of the Use of Regular Haem Arginate Infusions in Patients with Acute Porphyria to Prevent Recurrent Symptoms. ( 25762493 )
2015
15
Acute porphyria precipitated by efavirenz. ( 25909830 )
2015
16
Successful administration of sugammadex in a patient with acute porphyria: A case report. ( 24992602 )
2014
17
Lead poisoning mimicking acute porphyria! ( 25653942 )
2014
18
Alterations of the redox state, pentose pathway and glutathione metabolism in an acute porphyria model. Their impact on heme pathway. ( 23390166 )
2013
19
Acute porphyria presenting as epilepsia partialis continua. ( 23898283 )
2013
20
Review of hepatocellular cancer, hypertension and renal impairment as late complications of acute porphyria and recommendations for patient follow-up. ( 22851509 )
2012
21
Sustained enzymatic correction by rAAV-mediated liver gene therapy protects against induced motor neuropathy in acute porphyria mice. ( 20877347 )
2011
22
How porphyrinogenic drugs modeling acute porphyria impair the hormonal status that regulates glucose metabolism. Their relevance in the onset of this disease. ( 21889565 )
2011
23
Schizoaffective disorder with missed diagnosis of acute porphyria: a case report and overview. ( 22454794 )
2011
24
Evaluation of gonadotropin-releasing hormone agonist treatment for prevention of menstrual-related attacks in acute porphyria. ( 20021268 )
2010
25
A retrospective analysis of outcome of pregnancy in patients with acute porphyria. ( 20567908 )
2010
26
Acute porphyria precipitated by nevirapine. ( 20940539 )
2010
27
Thomas Wakley, King George III and acute porphyria. ( 19966121 )
2009
28
Hepatic alteration of tryptophan metabolism in an acute porphyria model Its relation with gluconeogenic blockage. ( 17996218 )
2008
29
Identifying acute porphyria in patients with acute polyneuropathy or encephalopathy. ( 19002132 )
2008
30
Nitric oxide and the clinical manifestations of acute porphyria. ( 19143888 )
2008
31
Treatment options in acute porphyria, porphyria cutanea tarda, and erythropoietic protoporphyria. ( 18221605 )
2007
32
Open-label study of hemin for acute porphyria: clinical practice implications. ( 16945618 )
2006
33
Immunosuppressive therapy for acute porphyria: safety and efficacy in a patient with bone marrow failure. ( 17064214 )
2006
34
(Far) Outside the box: genomic approach to acute porphyria. ( 17298222 )
2006
35
ED presentation of acute porphyria. ( 15765337 )
2005
36
Response of glucose metabolism enzymes in an acute porphyria model. Role of reactive oxygen species. ( 16125296 )
2005
37
Clinical features predictive of a poor prognosis in acute porphyria. ( 15645362 )
2004
38
Olanzapine use in acute porphyria. ( 24937245 )
2003
39
A study of 24-hour ambulatory blood pressure monitoring in cases of intermittent acute porphyria with hypertension: special reference to safety and efficacy of angiotensin-converting enzyme inhibitor (enalapril) therapy. ( 12674196 )
2002
40
Treatment of acute porphyria. ( 11480131 )
2001
41
Lipoprotein abnormalities in patients with asymptomatic acute porphyria. ( 10727671 )
2000
42
Study of motor and sensory nerve conduction velocities, late responses (F-wave and H-reflex) and somatosensory evoked potential in latent phase of intermittent acute porphyria. ( 10746181 )
2000
43
Acute porphyria following commencement of indinavir. ( 10203389 )
1999
44
Motor neuropathy in porphobilinogen deaminase-deficient mice imitates the peripheral neuropathy of human acute porphyria. ( 10207164 )
1999
45
A new approach for the treatment of acute porphyria. ( 10361901 )
1999
46
The effect of therapeutic drugs and other pharmacologic agents on activity of porphobilinogen deaminase, the enzyme that is deficient in intermittent acute porphyria. ( 10416826 )
1999
47
Acute porphyria: the cost of suspicion. ( 10625031 )
1999
48
Acute porphyria: treatment with heme. ( 9516678 )
1998
49
Identification of acute porphyria: evaluation of a commercial screening test for urinary porphobilinogen. ( 9838985 )
1998
50
King George III and acute porphyria. ( 9024414 )
1997

Variations for Acute Porphyria

ClinVar genetic disease variations for Acute Porphyria:

6
# Gene Variation Type Significance SNP ID Assembly Location
1 CPOX NM_000097.5(CPOX): c.814A> C (p.Asn272His) single nucleotide variant Benign rs1131857 GRCh38 Chromosome 3, 98588852: 98588852
2 CPOX NM_000097.5(CPOX): c.814A> C (p.Asn272His) single nucleotide variant Benign rs1131857 GRCh37 Chromosome 3, 98307696: 98307696
3 PPOX NM_000309.4(PPOX): c.590T> C (p.Ile197Thr) single nucleotide variant not provided rs1553238545 GRCh37 Chromosome 1, 161138340: 161138340
4 PPOX NM_000309.4(PPOX): c.590T> C (p.Ile197Thr) single nucleotide variant not provided rs1553238545 GRCh38 Chromosome 1, 161168550: 161168550

Expression for Acute Porphyria

Search GEO for disease gene expression data for Acute Porphyria.

Pathways for Acute Porphyria

Pathways related to Acute Porphyria according to KEGG:

38
# Name Kegg Source Accession
1 Porphyrin and chlorophyll metabolism hsa00860

GO Terms for Acute Porphyria

Cellular components related to Acute Porphyria according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 mitochondrial matrix GO:0005759 9.26 ALAS1 ALAS2 FECH PC
2 mitochondrion GO:0005739 9.23 ALAS1 ALAS2 CPOX FECH GLUL PC

Biological processes related to Acute Porphyria according to GeneCards Suite gene sharing:

(show all 14)
# Name GO ID Score Top Affiliating Genes
1 heme biosynthetic process GO:0006783 9.81 ALAD ALAS1 ALAS2 CPOX FECH HMBS
2 tetrapyrrole biosynthetic process GO:0033014 9.65 ALAD ALAS1 ALAS2 HMBS UROS
3 protoporphyrinogen IX biosynthetic process GO:0006782 9.56 ALAD ALAS1 ALAS2 CPOX HMBS PPOX
4 biosynthetic process GO:0009058 9.54 ALAS1 ALAS2
5 response to lead ion GO:0010288 9.51 ALAD FECH
6 response to platinum ion GO:0070541 9.5 ALAD FECH UROS
7 response to metal ion GO:0010038 9.49 ALAD FECH
8 response to iron ion GO:0010039 9.48 ALAD HFE
9 response to arsenic-containing substance GO:0046685 9.46 ALAD FECH
10 response to methylmercury GO:0051597 9.43 ALAD FECH
11 porphyrin-containing compound metabolic process GO:0006778 9.4 ALAS1 ALAS2
12 protoporphyrinogen IX metabolic process GO:0046501 9.37 FECH PPOX
13 intracellular receptor signaling pathway GO:0030522 9.22 NR1I2
14 porphyrin-containing compound biosynthetic process GO:0006779 9.17 ALAD CPOX FECH HMBS PPOX UROD

Molecular functions related to Acute Porphyria according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 catalytic activity GO:0003824 9.46 ALAD ALAS2 GLUL PC
2 nuclear receptor activity GO:0004879 8.96 NR1I2
3 5-aminolevulinate synthase activity GO:0003870 8.96 ALAS1 ALAS2
4 lyase activity GO:0016829 8.92 ALAD FECH UROD UROS

Sources for Acute Porphyria

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
17 EFO
18 ExPASy
20 FMA
29 GO
30 GTR
31 HGMD
32 HMDB
33 HPO
34 ICD10
35 ICD10 via Orphanet
36 ICD9CM
37 IUPHAR
38 KEGG
39 LifeMap
41 LOVD
43 MedGen
45 MeSH
46 MESH via Orphanet
47 MGI
50 NCI
51 NCIt
52 NDF-RT
55 NINDS
56 Novoseek
58 OMIM
59 OMIM via Orphanet
63 PubMed
65 QIAGEN
70 SNOMED-CT via HPO
71 SNOMED-CT via Orphanet
72 TGDB
73 Tocris
74 UMLS
75 UMLS via Orphanet
Content
Loading form....