MCID: ACT079
MIFTS: 29

Acute Proliferative Glomerulonephritis

Categories: Nephrological diseases

Aliases & Classifications for Acute Proliferative Glomerulonephritis

MalaCards integrated aliases for Acute Proliferative Glomerulonephritis:

Name: Acute Proliferative Glomerulonephritis 12 15 74
Acute Glomerulonephritis with Lesion of Proliferative Glomerulonephritis 12
Acute Post-Streptococcal Glomerulonephritis 74

Classifications:



External Ids:

Disease Ontology 12 DOID:13138
ICD9CM 36 580.0

Summaries for Acute Proliferative Glomerulonephritis

MalaCards based summary : Acute Proliferative Glomerulonephritis, also known as acute glomerulonephritis with lesion of proliferative glomerulonephritis, is related to proliferative glomerulonephritis and glomerulonephritis. An important gene associated with Acute Proliferative Glomerulonephritis is MPO (Myeloperoxidase), and among its related pathways/superpathways are Selenium Micronutrient Network and G-protein signaling Regulation of p38 and JNK signaling mediated by G-proteins. The drugs Antistreptolysin and Immunologic Factors have been mentioned in the context of this disorder. Affiliated tissues include skin, kidney and neutrophil.

Wikipedia : 77 Acute proliferative glomerulonephritis is a disorder of the glomeruli (glomerulonephritis), or small... more...

Related Diseases for Acute Proliferative Glomerulonephritis

Diseases in the Proliferative Glomerulonephritis family:

Acute Proliferative Glomerulonephritis

Diseases related to Acute Proliferative Glomerulonephritis via text searches within MalaCards or GeneCards Suite gene sharing:

(show all 34)
# Related Disease Score Top Affiliating Genes
1 proliferative glomerulonephritis 30.9 CCL2 MPO
2 glomerulonephritis 29.3 CCL2 COL4A3 ICAM1 MPO NPHS1
3 cerebral aneurysms 10.3 CCL2 MPO
4 ascending cholangitis 10.3 CCL2 MPO
5 anti-basement membrane glomerulonephritis 10.3 COL4A3 EDA
6 hypersensitivity vasculitis 10.3 MPO PIGN
7 diffuse cutaneous systemic sclerosis 10.2 CCR6 ICOSLG
8 stromal keratitis 10.2 CCL2 CCR6
9 goodpasture syndrome 10.1 COL4A3 EDA MPO
10 immune-complex glomerulonephritis 10.1 ICAM1 MPO
11 herpes simplex virus keratitis 10.1 CCL2 ICAM1
12 leukostasis 10.1 ICAM1 MPO
13 hypersensitivity reaction type iii disease 10.1 ICAM1 MPO
14 autoimmune glomerulonephritis 10.0 COL4A3 ICAM1
15 macular retinal edema 10.0 CCL2 ICAM1
16 post-thrombotic syndrome 10.0 CCL2 ICAM1
17 henoch-schoenlein purpura 10.0 ICAM1 MPO
18 rapidly progressive glomerulonephritis 10.0 ICAM1 MPO PIGN
19 pleurisy 10.0 CCL2 ICAM1 MPO
20 peritonitis 10.0 CCL2 ICAM1 MPO
21 proteasome-associated autoinflammatory syndrome 1 10.0 CCL2 ICAM1 MPO
22 respiratory system disease 9.9 CCL2 ICAM1 MPO
23 familial idiopathic steroid-resistant nephrotic syndrome with focal segmental hyalinosis 9.9 COL4A3 NPHS1
24 diabetic macular edema 9.9 CCL2 ICAM1
25 extrinsic cardiomyopathy 9.9 CCL2 ICAM1
26 autoimmune uveitis 9.8 CCL2 ICAM1
27 focal segmental glomerulosclerosis 1 9.8 ICAM1 NPHS1
28 vasculitis 9.7 BPI CCL2 ICAM1 MPO
29 lipoid nephrosis 9.7 CCL2 NPHS1 SYNPO
30 nephrosclerosis 9.7 CCL2 NPHS1 SYNPO
31 urinary system disease 9.7 CCL2 NPHS1 SYNPO
32 focal segmental glomerulosclerosis 9.6 COL4A3 NPHS1 SYNPO
33 membranoproliferative glomerulonephritis 9.4 ICAM1 NPHS1
34 crescentic glomerulonephritis 9.4 BPI CCL2 ICAM1 MPO SYNPO

Comorbidity relations with Acute Proliferative Glomerulonephritis via Phenotypic Disease Network (PDN):


Acute Kidney Failure Chronic Kidney Failure
Deficiency Anemia

Graphical network of the top 20 diseases related to Acute Proliferative Glomerulonephritis:



Diseases related to Acute Proliferative Glomerulonephritis

Symptoms & Phenotypes for Acute Proliferative Glomerulonephritis

Drugs & Therapeutics for Acute Proliferative Glomerulonephritis

Drugs for Acute Proliferative Glomerulonephritis (from DrugBank, HMDB, Dgidb, PharmGKB, IUPHAR, NovoSeek, BitterDB):


# Name Status Phase Clinical Trials Cas Number PubChem Id
1 Antistreptolysin
2 Immunologic Factors
3 Complement System Proteins

Interventional clinical trials:


# Name Status NCT ID Phase Drugs
1 Hospital Based Incidence of Group A Streptococcal Disease in Fiji Completed NCT00264771
2 Acute Post Streptococcal Glomerulonephritis Not yet recruiting NCT03184103

Search NIH Clinical Center for Acute Proliferative Glomerulonephritis

Genetic Tests for Acute Proliferative Glomerulonephritis

Anatomical Context for Acute Proliferative Glomerulonephritis

MalaCards organs/tissues related to Acute Proliferative Glomerulonephritis:

42
Skin, Kidney, Neutrophil

Publications for Acute Proliferative Glomerulonephritis

Articles related to Acute Proliferative Glomerulonephritis:

# Title Authors Year
1
Apoptosis and proliferation in childhood acute proliferative glomerulonephritis. ( 15965768 )
2005
2
Models of renal insufficiency: the anti-thy-1.1 model of acute proliferative glomerulonephritis. ( 21965074 )
2001
3
Acute proliferative glomerulonephritis with crescents and renal failure in pregnancy successfully managed by intermittent haemodialysis. Case report. ( 508665 )
1979
4
Platelet survival in acute proliferative glomerulonephritis. ( 4434691 )
1974
5
The relationship of neutrophilic and eosinophilic leukocytes to the glomerular capillary basement membrane in acute proliferative glomerulonephritis. ( 5136992 )
1971
6
Ultrastructural demonstration of injury and perforation of glomerular capillary basement membrane in acute proliferative glomerulonephritis. ( 4184004 )
1969

Variations for Acute Proliferative Glomerulonephritis

Expression for Acute Proliferative Glomerulonephritis

Search GEO for disease gene expression data for Acute Proliferative Glomerulonephritis.

Pathways for Acute Proliferative Glomerulonephritis

GO Terms for Acute Proliferative Glomerulonephritis

Cellular components related to Acute Proliferative Glomerulonephritis according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 extracellular space GO:0005615 9.43 BPI CCL2 COL4A3 ICAM1 MPO PODXL
2 slit diaphragm GO:0036057 8.62 NPHS1 PODXL

Biological processes related to Acute Proliferative Glomerulonephritis according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 immune response GO:0006955 9.56 BPI CCL2 CCR6 EDA
2 cell adhesion GO:0007155 9.35 CCL2 COL4A3 ICAM1 NPHS1 PODXL
3 glomerular basement membrane development GO:0032836 9.16 COL4A3 NPHS1
4 glomerular visceral epithelial cell development GO:0072015 8.62 NPHS1 PODXL

Sources for Acute Proliferative Glomerulonephritis

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
17 EFO
18 ExPASy
20 FMA
29 GO
30 GTR
31 HGMD
32 HMDB
33 HPO
34 ICD10
35 ICD10 via Orphanet
36 ICD9CM
37 IUPHAR
38 KEGG
39 LifeMap
41 LOVD
43 MedGen
45 MeSH
46 MESH via Orphanet
47 MGI
50 NCI
51 NCIt
52 NDF-RT
55 NINDS
56 Novoseek
58 OMIM
59 OMIM via Orphanet
63 PubMed
65 QIAGEN
70 SNOMED-CT via HPO
71 SNOMED-CT via Orphanet
72 TGDB
73 Tocris
74 UMLS
75 UMLS via Orphanet
Content
Loading form....