MCID: ACT079
MIFTS: 31

Acute Proliferative Glomerulonephritis

Categories: Nephrological diseases

Aliases & Classifications for Acute Proliferative Glomerulonephritis

MalaCards integrated aliases for Acute Proliferative Glomerulonephritis:

Name: Acute Proliferative Glomerulonephritis 12 15 73
Acute Glomerulonephritis with Lesion of Proliferative Glomerulonephritis 12
Acute Post-Streptococcal Glomerulonephritis 73

Classifications:



External Ids:

Disease Ontology 12 DOID:13138
ICD9CM 35 580.0

Summaries for Acute Proliferative Glomerulonephritis

MalaCards based summary : Acute Proliferative Glomerulonephritis, also known as acute glomerulonephritis with lesion of proliferative glomerulonephritis, is related to proliferative glomerulonephritis and glomerulonephritis. An important gene associated with Acute Proliferative Glomerulonephritis is MPO (Myeloperoxidase), and among its related pathways/superpathways are Selenium Micronutrient Network and Ectoderm Differentiation. The drugs Complement System Proteins and Immunologic Factors have been mentioned in the context of this disorder. Affiliated tissues include skin, kidney and heart.

Wikipedia : 76 Acute proliferative glomerulonephritis is a disorder of the glomeruli (glomerulonephritis), or small... more...

Related Diseases for Acute Proliferative Glomerulonephritis

Diseases in the Proliferative Glomerulonephritis family:

Acute Proliferative Glomerulonephritis

Diseases related to Acute Proliferative Glomerulonephritis via text searches within MalaCards or GeneCards Suite gene sharing:

(show all 44)
# Related Disease Score Top Affiliating Genes
1 proliferative glomerulonephritis 30.7 CCL2 MPO
2 glomerulonephritis 29.8 CCL2 COL4A3 ICAM1 MPO NPHS1
3 cerebral aneurysms 10.2 CCL2 MPO
4 ascending cholangitis 10.2 CCL2 MPO
5 hypersensitivity vasculitis 10.2 MPO PIGN
6 aleukemic leukemia cutis 10.2 LYZ MPO
7 ulcerative stomatitis 10.2 LYZ MPO
8 carbuncle 10.2 LYZ MPO
9 xanthogranulomatous pyelonephritis 10.2 CCL2 LYZ
10 pulmonary hemosiderosis 10.2 LYZ MPO
11 anti-basement membrane glomerulonephritis 10.1 COL4A3 EDA
12 tuberculous meningitis 10.1 CCL2 LYZ
13 pelvic inflammatory disease 10.1 CCL2 MPO
14 immune-complex glomerulonephritis 10.1 ICAM1 MPO
15 herpes simplex virus keratitis 10.1 CCL2 ICAM1
16 chronic eosinophilic pneumonia 10.1 CCL2 ICAM1
17 leukostasis 10.1 ICAM1 MPO
18 macular retinal edema 10.1 CCL2 ICAM1
19 hypersensitivity reaction type iii disease 10.1 ICAM1 MPO
20 pollen allergy 10.1 ICAM1 MPO
21 post-thrombotic syndrome 10.1 CCL2 ICAM1
22 goodpasture syndrome 10.0 COL4A3 EDA MPO
23 familial idiopathic steroid-resistant nephrotic syndrome with focal segmental hyalinosis 10.0 COL4A3 NPHS1
24 henoch-schoenlein purpura 10.0 ICAM1 MPO
25 focal segmental glomerulosclerosis 1 10.0 ICAM1 NPHS1
26 rapidly progressive glomerulonephritis 10.0 ICAM1 MPO PIGN
27 diabetic macular edema 10.0 CCL2 ICAM1
28 autoimmune glomerulonephritis 10.0 COL4A3 ICAM1
29 pleurisy 10.0 CCL2 ICAM1 MPO
30 peritonitis 10.0 CCL2 ICAM1 MPO
31 proteasome-associated autoinflammatory syndrome 1 10.0 CCL2 ICAM1 MPO
32 respiratory system disease 10.0 CCL2 ICAM1 MPO
33 extrinsic cardiomyopathy 10.0 CCL2 ICAM1
34 autoimmune uveitis 10.0 CCL2 ICAM1
35 bardet-biedl syndrome 2 9.9 ICAM1 LYZ
36 membranoproliferative glomerulonephritis 9.9 ICAM1 NPHS1
37 vasculitis 9.9 BPI CCL2 ICAM1 MPO
38 lipoid nephrosis 9.8 CCL2 NPHS1 SYNPO
39 nephrosclerosis 9.8 CCL2 NPHS1 SYNPO
40 inflammatory bowel disease 9.8 BPI CCL2 ICAM1 MPO
41 focal segmental glomerulosclerosis 9.7 COL4A3 NPHS1 SYNPO
42 urinary system disease 9.7 CCL2 LYZ NPHS1 SYNPO
43 galloway-mowat syndrome 9.7 NPHS1 SYNPO
44 crescentic glomerulonephritis 9.6 BPI CCL2 ICAM1 MPO SYNPO

Comorbidity relations with Acute Proliferative Glomerulonephritis via Phenotypic Disease Network (PDN):


Acute Kidney Failure Chronic Kidney Failure
Deficiency Anemia

Graphical network of the top 20 diseases related to Acute Proliferative Glomerulonephritis:



Diseases related to Acute Proliferative Glomerulonephritis

Symptoms & Phenotypes for Acute Proliferative Glomerulonephritis

Drugs & Therapeutics for Acute Proliferative Glomerulonephritis

Drugs for Acute Proliferative Glomerulonephritis (from DrugBank, HMDB, Dgidb, PharmGKB, IUPHAR, NovoSeek, BitterDB):


# Name Status Phase Clinical Trials Cas Number PubChem Id
1 Complement System Proteins
2 Immunologic Factors
3 Antistreptolysin

Interventional clinical trials:


# Name Status NCT ID Phase Drugs
1 Hospital Based Incidence of Group A Streptococcal Disease in Fiji Completed NCT00264771
2 Acute Post Streptococcal Glomerulonephritis Not yet recruiting NCT03184103

Search NIH Clinical Center for Acute Proliferative Glomerulonephritis

Genetic Tests for Acute Proliferative Glomerulonephritis

Anatomical Context for Acute Proliferative Glomerulonephritis

MalaCards organs/tissues related to Acute Proliferative Glomerulonephritis:

41
Skin, Kidney, Heart, Neutrophil

Publications for Acute Proliferative Glomerulonephritis

Articles related to Acute Proliferative Glomerulonephritis:

# Title Authors Year
1
Apoptosis and proliferation in childhood acute proliferative glomerulonephritis. ( 15965768 )
2005
2
Models of renal insufficiency: the anti-thy-1.1 model of acute proliferative glomerulonephritis. ( 21965074 )
2001
3
Acute proliferative glomerulonephritis with crescents and renal failure in pregnancy successfully managed by intermittent haemodialysis. Case report. ( 508665 )
1979
4
Platelet survival in acute proliferative glomerulonephritis. ( 4434691 )
1974
5
The relationship of neutrophilic and eosinophilic leukocytes to the glomerular capillary basement membrane in acute proliferative glomerulonephritis. ( 5136992 )
1971
6
Ultrastructural demonstration of injury and perforation of glomerular capillary basement membrane in acute proliferative glomerulonephritis. ( 4184004 )
1969

Variations for Acute Proliferative Glomerulonephritis

Expression for Acute Proliferative Glomerulonephritis

Search GEO for disease gene expression data for Acute Proliferative Glomerulonephritis.

Pathways for Acute Proliferative Glomerulonephritis

GO Terms for Acute Proliferative Glomerulonephritis

Cellular components related to Acute Proliferative Glomerulonephritis according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 extracellular exosome GO:0070062 9.73 BPI ICAM1 LYZ MPO NPHS1 PODXL
2 azurophil granule lumen GO:0035578 9.33 BPI LYZ MPO
3 extracellular space GO:0005615 9.17 BPI CCL2 COL4A3 ICAM1 LYZ MPO
4 slit diaphragm GO:0036057 8.96 NPHS1 PODXL

Biological processes related to Acute Proliferative Glomerulonephritis according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 defense response to bacterium GO:0042742 9.43 BPI LYZ MPO
2 glomerular basement membrane development GO:0032836 9.16 COL4A3 NPHS1
3 cell adhesion GO:0007155 9.02 CCL2 COL4A3 ICAM1 NPHS1 PODXL
4 glomerular visceral epithelial cell development GO:0072015 8.96 NPHS1 PODXL

Sources for Acute Proliferative Glomerulonephritis

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
17 ExPASy
19 FMA
28 GO
29 GTR
30 HGMD
31 HMDB
32 HPO
33 ICD10
34 ICD10 via Orphanet
35 ICD9CM
36 IUPHAR
37 KEGG
38 LifeMap
40 LOVD
42 MedGen
44 MeSH
45 MESH via Orphanet
46 MGI
49 NCI
50 NCIt
51 NDF-RT
54 NINDS
55 Novoseek
57 OMIM
58 OMIM via Orphanet
62 PubMed
64 QIAGEN
69 SNOMED-CT via HPO
70 SNOMED-CT via Orphanet
71 TGDB
72 Tocris
73 UMLS
74 UMLS via Orphanet
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