MCID: ACT079
MIFTS: 32

Acute Proliferative Glomerulonephritis

Categories: Nephrological diseases

Aliases & Classifications for Acute Proliferative Glomerulonephritis

MalaCards integrated aliases for Acute Proliferative Glomerulonephritis:

Name: Acute Proliferative Glomerulonephritis 12 15 73
Acute Glomerulonephritis with Lesion of Proliferative Glomerulonephritis 12
Acute Post-Streptococcal Glomerulonephritis 73

Classifications:



External Ids:

Disease Ontology 12 DOID:13138
ICD9CM 35 580.0
SNOMED-CT 68 197579006
UMLS 73 C0341692

Summaries for Acute Proliferative Glomerulonephritis

MalaCards based summary : Acute Proliferative Glomerulonephritis, also known as acute glomerulonephritis with lesion of proliferative glomerulonephritis, is related to proliferative glomerulonephritis and glomerulonephritis. An important gene associated with Acute Proliferative Glomerulonephritis is MPO (Myeloperoxidase), and among its related pathways/superpathways are Innate Immune System and NF-kappaB Signaling. The drugs Antistreptolysin and Complement System Proteins have been mentioned in the context of this disorder. Affiliated tissues include kidney, skin and neutrophil.

Wikipedia : 76 Acute proliferative glomerulonephritis is a disorder of the glomeruli (glomerulonephritis), or small... more...

Related Diseases for Acute Proliferative Glomerulonephritis

Diseases in the Proliferative Glomerulonephritis family:

Acute Proliferative Glomerulonephritis

Diseases related to Acute Proliferative Glomerulonephritis via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50) (show all 155)
# Related Disease Score Top Affiliating Genes
1 proliferative glomerulonephritis 30.3 CCL2 CD79A
2 glomerulonephritis 28.2 CCL2 CD40LG CD79A COL4A3 ICAM1 MPO
3 maxillary sinusitis 10.9 CD79A MPO
4 cerebral aneurysms 10.8 CCL2 MPO
5 ulcerative blepharitis 10.8 CD79A LYZ
6 selective igg deficiency disease 10.8 CD40LG CD79A
7 c1q nephropathy 10.8 CD40LG CD79A
8 meningovascular neurosyphilis 10.8 CD40LG CD79A
9 alpha chain disease 10.8 CD40LG CD79A
10 brill-zinsser disease 10.8 CD40LG CD79A
11 exudative glomerulonephritis 10.8 CD40LG CD79A
12 cork-handlers' disease 10.8 CD40LG CD79A
13 salpingo-oophoritis 10.8 CD40LG CD79A
14 early yaws 10.7 CD40LG CD79A
15 ventilation pneumonitis 10.7 CD40LG CD79A
16 chronic interstitial cystitis 10.7 CD40LG CD79A
17 axillary adenitis 10.7 CD40LG CD79A
18 cryofibrinogenemia 10.7 CD40LG CD79A
19 mononeuritis multiplex 10.7 CD40LG MPO
20 trichostrongyloidiasis 10.7 CD40LG CD79A
21 mononeuritis of upper limb and mononeuritis multiplex 10.7 CD40LG MPO
22 subacute bacterial endocarditis 10.7 CD40LG CD79A
23 immunoglobulin g deficiency 10.7 CD40LG CD79A
24 orbital granuloma 10.7 CD40LG CD79A
25 transient hypogammaglobulinemia of infancy 10.7 CD40LG CD79A
26 hyperglobulinemic purpura 10.7 CD40LG CD79A
27 gastroduodenitis 10.7 CD40LG CD79A
28 bacterial conjunctivitis 10.7 CD40LG CD79A
29 heavy chain disease 10.7 CD40LG CD79A
30 ophthalmia neonatorum 10.7 CD40LG CD79A
31 immunoglobulin a deficiency 1 10.7 CD40LG CD79A
32 parotid disease 10.7 CD40LG CD79A
33 selective immunoglobulin deficiency disease 10.7 CD40LG CD79A
34 geniculate herpes zoster 10.7 CD40LG CD79A
35 erythema elevatum diutinum 10.7 CD40LG CD79A
36 collagenous colitis 10.7 CD79A MPO
37 sporotrichosis 10.7 CD40LG CD79A
38 fallopian tube disease 10.7 CD40LG CD79A
39 hyperimmunoglobulin syndrome 10.7 CD40LG CD79A
40 congenital syphilis 10.7 CD40LG CD79A
41 polyclonal hypergammaglobulinemia 10.7 CD40LG CD79A
42 salpingitis 10.7 CD40LG CD79A
43 ocular toxoplasmosis 10.7 CD40LG CD79A
44 dysgammaglobulinemia 10.7 CD40LG CD79A
45 congenital hypogammaglobulinemia 10.7 CD40LG CD79A
46 microscopic colitis 10.7 CD79A LYZ
47 acute maxillary sinusitis 10.7 CD40LG CD79A
48 chronic polyneuropathy 10.7 CD40LG CD79A
49 spinocerebellar ataxia, autosomal recessive 10 10.7 CD40LG CD79A
50 parasitic ichthyosporea infectious disease 10.7 CD40LG CD79A

Comorbidity relations with Acute Proliferative Glomerulonephritis via Phenotypic Disease Network (PDN):


Acute Kidney Failure Chronic Kidney Failure
Deficiency Anemia

Graphical network of the top 20 diseases related to Acute Proliferative Glomerulonephritis:



Diseases related to Acute Proliferative Glomerulonephritis

Symptoms & Phenotypes for Acute Proliferative Glomerulonephritis

Drugs & Therapeutics for Acute Proliferative Glomerulonephritis

Drugs for Acute Proliferative Glomerulonephritis (from DrugBank, HMDB, Dgidb, PharmGKB, IUPHAR, NovoSeek, BitterDB):


# Name Status Phase Clinical Trials Cas Number PubChem Id
1 Antistreptolysin
2 Complement System Proteins

Interventional clinical trials:


# Name Status NCT ID Phase Drugs
1 Hospital Based Incidence of Group A Streptococcal Disease in Fiji Completed NCT00264771
2 Acute Post Streptococcal Glomerulonephritis Not yet recruiting NCT03184103

Search NIH Clinical Center for Acute Proliferative Glomerulonephritis

Genetic Tests for Acute Proliferative Glomerulonephritis

Anatomical Context for Acute Proliferative Glomerulonephritis

MalaCards organs/tissues related to Acute Proliferative Glomerulonephritis:

41
Kidney, Skin, Neutrophil

Publications for Acute Proliferative Glomerulonephritis

Articles related to Acute Proliferative Glomerulonephritis:

# Title Authors Year
1
Apoptosis and proliferation in childhood acute proliferative glomerulonephritis. ( 15965768 )
2005
2
Models of renal insufficiency: the anti-thy-1.1 model of acute proliferative glomerulonephritis. ( 21965074 )
2001
3
Acute proliferative glomerulonephritis with crescents and renal failure in pregnancy successfully managed by intermittent haemodialysis. Case report. ( 508665 )
1979
4
Platelet survival in acute proliferative glomerulonephritis. ( 4434691 )
1974
5
The relationship of neutrophilic and eosinophilic leukocytes to the glomerular capillary basement membrane in acute proliferative glomerulonephritis. ( 5136992 )
1971
6
Ultrastructural demonstration of injury and perforation of glomerular capillary basement membrane in acute proliferative glomerulonephritis. ( 4184004 )
1969

Variations for Acute Proliferative Glomerulonephritis

Expression for Acute Proliferative Glomerulonephritis

Search GEO for disease gene expression data for Acute Proliferative Glomerulonephritis.

Pathways for Acute Proliferative Glomerulonephritis

Pathways related to Acute Proliferative Glomerulonephritis according to GeneCards Suite gene sharing:

# Super pathways Score Top Affiliating Genes
1
Show member pathways
13.6 BPI CCL2 CD40LG CD79A EDA ICAM1
2 12.07 CCL2 CD40LG CD79A MPO
3 11.66 CCL2 EDA PODXL
4 11.33 CCL2 COL4A3 ICAM1
5 10.94 CCL2 CD40LG
6 10.82 CCL2 CD40LG ICAM1
7 10.77 CCL2 ICAM1
8 10 CCL2 ICAM1 MPO

GO Terms for Acute Proliferative Glomerulonephritis

Cellular components related to Acute Proliferative Glomerulonephritis according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 extracellular region GO:0005576 9.8 BPI CCL2 CD40LG COL4A3 EDA LYZ
2 integral component of plasma membrane GO:0005887 9.63 BPI CD40LG CD79A EDA ICAM1 PODXL
3 extracellular space GO:0005615 9.17 BPI CCL2 CD40LG ICAM1 LYZ MPO
4 azurophil granule lumen GO:0035578 9.13 BPI LYZ MPO

Biological processes related to Acute Proliferative Glomerulonephritis according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 immune response GO:0006955 9.46 BPI CCL2 CD40LG EDA
2 B cell proliferation GO:0042100 9.32 CD40LG CD79A
3 leukocyte cell-cell adhesion GO:0007159 9.26 CD40LG ICAM1
4 positive regulation of endothelial cell apoptotic process GO:2000353 8.96 CCL2 CD40LG
5 positive regulation of NF-kappaB transcription factor activity GO:0051092 8.8 CD40LG EDA ICAM1

Molecular functions related to Acute Proliferative Glomerulonephritis according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 tumor necrosis factor receptor binding GO:0005164 8.62 CD40LG EDA

Sources for Acute Proliferative Glomerulonephritis

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
17 ExPASy
19 FMA
28 GO
29 GTR
30 HGMD
31 HMDB
32 HPO
33 ICD10
34 ICD10 via Orphanet
35 ICD9CM
36 IUPHAR
37 KEGG
38 LifeMap
40 LOVD
42 MedGen
44 MeSH
45 MESH via Orphanet
46 MGI
49 NCI
50 NCIt
51 NDF-RT
54 NINDS
55 Novoseek
57 OMIM
58 OMIM via Orphanet
62 PubMed
64 QIAGEN
69 SNOMED-CT via HPO
70 SNOMED-CT via Orphanet
71 TGDB
72 Tocris
73 UMLS
74 UMLS via Orphanet
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