MCID: ACT080
MIFTS: 26

Acute Pulmonary Heart Disease

Categories: Cardiovascular diseases, Respiratory diseases

Aliases & Classifications for Acute Pulmonary Heart Disease

MalaCards integrated aliases for Acute Pulmonary Heart Disease:

Name: Acute Pulmonary Heart Disease 12 15 71

Classifications:



External Ids:

Disease Ontology 12 DOID:8514
ICD9CM 34 415
SNOMED-CT 67 155324005
UMLS 71 C0155671

Summaries for Acute Pulmonary Heart Disease

MalaCards based summary : Acute Pulmonary Heart Disease is related to pulmonary embolism and thrombophilia due to thrombin defect. An important gene associated with Acute Pulmonary Heart Disease is NPPB (Natriuretic Peptide B), and among its related pathways/superpathways are Folate Metabolism and Formation of Fibrin Clot (Clotting Cascade). Affiliated tissues include heart, and related phenotypes are muscle and respiratory system

Related Diseases for Acute Pulmonary Heart Disease

Diseases in the Acute Pulmonary Heart Disease family:

Chronic Pulmonary Heart Disease

Diseases related to Acute Pulmonary Heart Disease via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50) (show all 190)
# Related Disease Score Top Affiliating Genes
1 pulmonary embolism 30.1 PLAT NPPB F3 F2
2 thrombophilia due to thrombin defect 29.9 PLAT F3 F2
3 heart disease 29.0 REN PLAT NPPB F3 F2
4 acute cor pulmonale 27.7 TSPAN15 REN PLG PLAT NPR2 NPPB
5 lujo hemorrhagic fever 10.3 NPPB F3
6 medulloadrenal hyperfunction 10.3 PLG F3
7 cardiogenic shock 10.2 PLAT NPPB
8 basal ganglia cerebrovascular disease 10.2 PLG PLAT
9 anterolateral myocardial infarction 10.2 PLAT NPPB
10 ligneous conjunctivitis 10.2 PLG PLAT
11 leech infestation 10.2 PLG F3
12 basilar artery insufficiency 10.2 PLG PLAT
13 retinal artery occlusion 10.2 PLG F2
14 brain stem infarction 10.2 PLG PLAT
15 vertebral artery occlusion 10.2 PLG PLAT
16 plasminogen deficiency, type i 10.2 PLG PLAT
17 conversion disorder 10.2 PLG PLAT
18 anterior spinal artery syndrome 10.2 PLG F2
19 retinal vein occlusion 10.2 F3 F2
20 perforated corneal ulcer 10.2 PLG PLAT
21 hereditary angioedema with normal c1inh 10.2 PLG PLAT
22 achenbach syndrome 10.2 F3 F2
23 thoracic outlet syndrome 10.2 PLG F2
24 middle cerebral artery infarction 10.2 PLG PLAT
25 renal pelvis squamous cell carcinoma 10.2 F3 F2
26 livedoid vasculitis 10.2 PLG F2
27 kidney cortex necrosis 10.2 PLG F2
28 synovial angioma 10.2 F3 F2
29 papillary adenofibroma 10.2 F3 F2
30 emphysematous cholecystitis 10.2 F3 F2
31 giant hemangioma 10.2 F3 F2
32 hemopneumothorax 10.2 F3 F2
33 dic in newborn 10.2 F3 F2
34 ankylosing spondylitis 1 10.2 F3 F2
35 waterhouse-friderichsen syndrome 10.2 F3 F2
36 epidural abscess 10.2 F3 F2
37 lemierre's syndrome 10.2 F3 F2
38 branch retinal artery occlusion 10.2 PLG F2
39 gastric hemangioma 10.2 F3 F2
40 hepatic infarction 10.2 F3 F2
41 splenic abscess 10.2 F3 F2
42 qualitative platelet defect 10.2 F3 F2
43 mediastinitis 10.2 F3 F2
44 cerebral sinovenous thrombosis 10.2 F3 F2
45 carotid artery occlusion 10.2 PLG PLAT
46 pleural empyema 10.2 PLG F2
47 prothrombin deficiency 10.2 F3 F2
48 intracranial hypotension 10.2 F3 F2
49 acquired von willebrand syndrome 10.2 F3 F2
50 active peptic ulcer disease 10.2 F3 F2

Graphical network of the top 20 diseases related to Acute Pulmonary Heart Disease:



Diseases related to Acute Pulmonary Heart Disease

Symptoms & Phenotypes for Acute Pulmonary Heart Disease

MGI Mouse Phenotypes related to Acute Pulmonary Heart Disease:

46
# Description MGI Source Accession Score Top Affiliating Genes
1 muscle MP:0005369 9.35 F2 F3 NPR2 PLAT REN
2 respiratory system MP:0005388 9.02 F2 F3 NPR2 PLAT PLG

Drugs & Therapeutics for Acute Pulmonary Heart Disease

Search Clinical Trials , NIH Clinical Center for Acute Pulmonary Heart Disease

Genetic Tests for Acute Pulmonary Heart Disease

Anatomical Context for Acute Pulmonary Heart Disease

MalaCards organs/tissues related to Acute Pulmonary Heart Disease:

40
Heart

Publications for Acute Pulmonary Heart Disease

Articles related to Acute Pulmonary Heart Disease:

(show all 16)
# Title Authors PMID Year
1
[Acute pulmonary heart disease caused by pulmonary artery embolism]. 61
10429913 1999
2
[The value of transesophageal echocardiography for the diagnosis of pulmonary embolism with acute pulmonary heart disease]. 61
9749175 1998
3
[Massive pulmonary artery embolism complicated by acute pulmonary heart disease]. 61
9181893 1996
4
[Structural and metabolic changes in the contractile myocardium in experimental acute pulmonary heart disease of vascular origin]. 61
7159237 1982
5
[Acute pulmonary heart disease in a person with chronic bronchopneumopathy and secondary heart disease. Uhlenbruck's syndrome]. 61
4693710 1973
6
[Acute pulmonary heart disease in resuscitation: case reports]. 61
4807138 1973
7
[A case of intermittent and transitory complete right branch block in embolic acute pulmonary heart disease]. 61
5138704 1971
8
[Acute pulmonary heart disease induced by repeated pulmonary embolisms. Embolectomy under extracorporeal circulation]. 61
5778506 1969
9
[ACUTE PULMONARY HEART DISEASE DUE TO AMNIOTIC EMBOLISM. EXPERIMENTAL STUDY]. 61
14289703 1965
10
[ACUTE PULMONARY HEART DISEASE. II. PULMONARY EMBOLISM]. 61
14251093 1964
11
[Various aspects of acute pulmonary heart disease caused by thromboembolism; doctrinal concept and antecedents]. 61
13358395 1956
12
[Pulmonary embolism and acute pulmonary heart disease; study of the syndrome and analysis of an observation]. 61
13308177 1955
13
[Acute pulmonary heart disease]. 61
14359694 1955
14
[Surgical indications in acute pulmonary heart disease caused by pulmonary embolism]. 61
13195717 1954
15
[Study on a cardiac output in acute pulmonary heart disease]. 61
13178378 1954
16
[Acute pulmonary heart disease in serious asthma; therapy and cure]. 61
13226252 1954

Variations for Acute Pulmonary Heart Disease

Expression for Acute Pulmonary Heart Disease

Search GEO for disease gene expression data for Acute Pulmonary Heart Disease.

Pathways for Acute Pulmonary Heart Disease

GO Terms for Acute Pulmonary Heart Disease

Cellular components related to Acute Pulmonary Heart Disease according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 extracellular region GO:0005576 9.73 REN PLG PLAT NPPB F3 F2
2 cell surface GO:0009986 9.46 TSPAN15 PLG PLAT F3
3 extracellular space GO:0005615 9.43 REN PLG PLAT NPPB F3 F2
4 collagen-containing extracellular matrix GO:0062023 8.92 PLG PLAT F3 F2

Biological processes related to Acute Pulmonary Heart Disease according to GeneCards Suite gene sharing:

(show all 11)
# Name GO ID Score Top Affiliating Genes
1 proteolysis GO:0006508 9.78 REN PLG PLAT F2
2 cellular protein metabolic process GO:0044267 9.67 TSPAN15 PLG F2
3 negative regulation of proteolysis GO:0045861 9.46 PLAT F2
4 cGMP-mediated signaling GO:0019934 9.43 NPR2 NPPB
5 regulation of blood pressure GO:0008217 9.43 REN NPR2 NPPB
6 cGMP biosynthetic process GO:0006182 9.4 NPR2 NPPB
7 negative regulation of fibrinolysis GO:0051918 9.37 PLG F2
8 hemostasis GO:0007599 9.33 PLG F3 F2
9 receptor guanylyl cyclase signaling pathway GO:0007168 9.32 NPR2 NPPB
10 blood coagulation GO:0007596 9.26 PLG PLAT F3 F2
11 fibrinolysis GO:0042730 8.8 PLG PLAT F2

Molecular functions related to Acute Pulmonary Heart Disease according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 peptidase activity GO:0008233 9.56 REN PLG PLAT F2
2 serine-type peptidase activity GO:0008236 9.33 PLG PLAT F2
3 serine-type endopeptidase activity GO:0004252 9.26 PLG PLAT F3 F2
4 signaling receptor binding GO:0005102 9.02 REN PLG PLAT NPPB F2

Sources for Acute Pulmonary Heart Disease

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
17 EFO
18 ExPASy
19 FMA
20 GARD
28 GO
29 GTR
30 HMDB
31 HPO
32 ICD10
33 ICD10 via Orphanet
34 ICD9CM
35 IUPHAR
36 KEGG
37 LifeMap
39 LOVD
41 MedGen
44 MeSH
45 MESH via Orphanet
46 MGI
49 NCI
50 NCIt
51 NDF-RT
53 NINDS
54 Novoseek
56 OMIM via Orphanet
57 OMIM® (Updated 05-Mar-2021)
61 PubMed
63 QIAGEN
68 SNOMED-CT via HPO
69 TGDB
70 Tocris
71 UMLS
72 UMLS via Orphanet
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