MCID: ACT080
MIFTS: 24

Acute Pulmonary Heart Disease

Categories: Cardiovascular diseases

Aliases & Classifications for Acute Pulmonary Heart Disease

MalaCards integrated aliases for Acute Pulmonary Heart Disease:

Name: Acute Pulmonary Heart Disease 12 15 72

Classifications:



External Ids:

Disease Ontology 12 DOID:8514
ICD9CM 35 415
SNOMED-CT 68 67189007
UMLS 72 C0155671

Summaries for Acute Pulmonary Heart Disease

MalaCards based summary : Acute Pulmonary Heart Disease is related to pulmonary embolism and acute cor pulmonale. An important gene associated with Acute Pulmonary Heart Disease is POR (Cytochrome P450 Oxidoreductase), and among its related pathways/superpathways are Response to elevated platelet cytosolic Ca2+ and Selenium Micronutrient Network. Affiliated tissues include heart, and related phenotype is cardiovascular system.

Related Diseases for Acute Pulmonary Heart Disease

Diseases in the Acute Pulmonary Heart Disease family:

Chronic Pulmonary Heart Disease

Diseases related to Acute Pulmonary Heart Disease via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50) (show all 60)
# Related Disease Score Top Affiliating Genes
1 pulmonary embolism 29.4 SERPINF2 SERPINE1 PLAT NPPB
2 acute cor pulmonale 25.5 VCL SERPINF2 SERPINE1 POR PLG PLAT
3 hemopericardium 10.5 SLC22A12 PLG
4 cardiogenic shock 10.5 PLAT NPPB
5 anterolateral myocardial infarction 10.5 PLAT NPPB
6 ligneous conjunctivitis 10.5 PLG PLAT
7 central retinal artery occlusion 10.4 PLG PLAT
8 occlusion precerebral artery 10.4 PLG PLAT
9 basilar artery occlusion 10.4 PLG PLAT
10 intermediate coronary syndrome 10.3 PLG PLAT
11 intestinal impaction 10.3 SERPINF2 PLG
12 giant hemangioma 10.3 SERPINF2 PLG
13 alpha-2-plasmin inhibitor deficiency 10.3 SERPINF2 PLG
14 pulmonary artery disease 10.3 PLG PLAT
15 tricuspid valve insufficiency 10.3 PDZK1IP1 NPPB
16 heart disease 10.3
17 acute poststreptococcal glomerulonephritis 10.3 SERPINF2 PLG
18 korean hemorrhagic fever 10.3 SERPINF2 PLG
19 tricuspid valve disease 10.3 PDZK1IP1 NPPB
20 platelet aggregation, spontaneous 10.2 SERPINF2 PLAT
21 inferior myocardial infarction 10.2 PLG PLAT NPPB
22 marantic endocarditis 10.2 SERPINF2 PLAT
23 tuberculous empyema 10.2 SERPINE1 PLG
24 fibrinolytic defect 10.2 SERPINE1 PLAT
25 blue toe syndrome 10.2 SERPINE1 PLG
26 mitral valve insufficiency 10.2 PDZK1IP1 NPPB
27 carotid artery dissection 10.2 PLG PLAT
28 central serous chorioretinopathy 10.2 SERPINE1 PLAT
29 argentine hemorrhagic fever 10.2 SERPINE1 PLAT
30 pregnancy adenoma 10.2 SERPINF2 PLAT
31 dysbaric osteonecrosis 10.2 SERPINE1 PLG
32 carotid artery thrombosis 10.1 SERPINE1 PLAT
33 lemierre's syndrome 10.1 SERPINE1 PLG
34 hepatic vascular disease 10.1 SERPINE1 PLG
35 coronary thrombosis 10.0 SERPINE1 PLAT
36 angina pectoris 10.0 SERPINF2 PLAT NPPB
37 intracranial embolism 10.0 SERPINF2 PLG PLAT
38 chronic venous insufficiency 10.0 SERPINE1 PLAT
39 heart valve disease 10.0 PDZK1IP1 NPPB
40 factor xiii deficiency 10.0 SERPINF2 SERPINE1
41 venous insufficiency 9.9 SERPINE1 PLAT
42 hepatic veno-occlusive disease 9.9 SERPINE1 PLG PLAT
43 vein disease 9.9 SERPINE1 PLG PLAT
44 coronary heart disease 1 9.9 SERPINE1 PLAT NPPB
45 myoma 9.8
46 afibrinogenemia, congenital 9.8 SERPINF2 PLAT
47 livedoid vasculitis 9.8 SERPINF2 SERPINE1 PLG
48 plasminogen activator inhibitor-1 deficiency 9.7 SERPINF2 SERPINE1 PLAT
49 thrombophlebitis 9.7 SERPINF2 SERPINE1 PLAT
50 disseminated intravascular coagulation 9.7 SERPINF2 SERPINE1 PLAT

Graphical network of the top 20 diseases related to Acute Pulmonary Heart Disease:



Diseases related to Acute Pulmonary Heart Disease

Symptoms & Phenotypes for Acute Pulmonary Heart Disease

MGI Mouse Phenotypes related to Acute Pulmonary Heart Disease:

46
# Description MGI Source Accession Score Top Affiliating Genes
1 cardiovascular system MP:0005385 9.17 CAST PLAT PLG POR SERPINE1 SLC22A12

Drugs & Therapeutics for Acute Pulmonary Heart Disease

Search Clinical Trials , NIH Clinical Center for Acute Pulmonary Heart Disease

Genetic Tests for Acute Pulmonary Heart Disease

Anatomical Context for Acute Pulmonary Heart Disease

MalaCards organs/tissues related to Acute Pulmonary Heart Disease:

41
Heart

Publications for Acute Pulmonary Heart Disease

Articles related to Acute Pulmonary Heart Disease:

(show all 16)
# Title Authors PMID Year
1
[Acute pulmonary heart disease caused by pulmonary artery embolism]. 38
10429913 1999
2
[The value of transesophageal echocardiography for the diagnosis of pulmonary embolism with acute pulmonary heart disease]. 38
9749175 1998
3
[Massive pulmonary artery embolism complicated by acute pulmonary heart disease]. 38
9181893 1996
4
[Structural and metabolic changes in the contractile myocardium in experimental acute pulmonary heart disease of vascular origin]. 38
7159237 1982
5
[Acute pulmonary heart disease in a person with chronic bronchopneumopathy and secondary heart disease. Uhlenbruck's syndrome]. 38
4693710 1973
6
[Acute pulmonary heart disease in resuscitation: case reports]. 38
4807138 1973
7
[A case of intermittent and transitory complete right branch block in embolic acute pulmonary heart disease]. 38
5138704 1971
8
[Acute pulmonary heart disease induced by repeated pulmonary embolisms. Embolectomy under extracorporeal circulation]. 38
5778506 1969
9
[ACUTE PULMONARY HEART DISEASE DUE TO AMNIOTIC EMBOLISM. EXPERIMENTAL STUDY]. 38
14289703 1965
10
[ACUTE PULMONARY HEART DISEASE. II. PULMONARY EMBOLISM]. 38
14251093 1964
11
[Various aspects of acute pulmonary heart disease caused by thromboembolism; doctrinal concept and antecedents]. 38
13358395 1956
12
[Pulmonary embolism and acute pulmonary heart disease; study of the syndrome and analysis of an observation]. 38
13308177 1955
13
[Acute pulmonary heart disease]. 38
14359694 1955
14
[Surgical indications in acute pulmonary heart disease caused by pulmonary embolism]. 38
13195717 1954
15
[Study on a cardiac output in acute pulmonary heart disease]. 38
13178378 1954
16
[Acute pulmonary heart disease in serious asthma; therapy and cure]. 38
13226252 1954

Variations for Acute Pulmonary Heart Disease

Expression for Acute Pulmonary Heart Disease

Search GEO for disease gene expression data for Acute Pulmonary Heart Disease.

Pathways for Acute Pulmonary Heart Disease

GO Terms for Acute Pulmonary Heart Disease

Cellular components related to Acute Pulmonary Heart Disease according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 extracellular region GO:0005576 9.73 VCL SERPINF2 SERPINE1 PLG PLAT NPPB
2 extracellular exosome GO:0070062 9.7 VCL SLC22A12 SERPINF2 SERPINE1 PLG PLAT
3 collagen-containing extracellular matrix GO:0062023 9.26 SERPINF2 SERPINE1 PLG PLAT
4 platelet alpha granule lumen GO:0031093 8.8 SERPINF2 SERPINE1 PLG

Biological processes related to Acute Pulmonary Heart Disease according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 negative regulation of peptidase activity GO:0010466 9.5 SERPINF2 SERPINE1 CAST
2 platelet degranulation GO:0002576 9.46 VCL SERPINF2 SERPINE1 PLG
3 negative regulation of plasminogen activation GO:0010757 9.26 SERPINF2 SERPINE1
4 negative regulation of fibrinolysis GO:0051918 9.13 SERPINF2 SERPINE1 PLG
5 fibrinolysis GO:0042730 8.92 SERPINF2 SERPINE1 PLG PLAT

Molecular functions related to Acute Pulmonary Heart Disease according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 signaling receptor binding GO:0005102 9.46 SERPINE1 PLG PLAT NPPB
2 endopeptidase inhibitor activity GO:0004866 9.26 SERPINF2 CAST
3 peptidase inhibitor activity GO:0030414 9.13 SERPINF2 SERPINE1 CAST
4 protease binding GO:0002020 8.8 SERPINF2 SERPINE1 CAST

Sources for Acute Pulmonary Heart Disease

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
17 EFO
18 ExPASy
19 FMA
28 GO
29 GTR
30 HGMD
31 HMDB
32 HPO
33 ICD10
34 ICD10 via Orphanet
35 ICD9CM
36 IUPHAR
37 KEGG
38 LifeMap
40 LOVD
42 MedGen
44 MeSH
45 MESH via Orphanet
46 MGI
49 NCI
50 NCIt
51 NDF-RT
54 NINDS
55 Novoseek
57 OMIM
58 OMIM via Orphanet
62 PubMed
64 QIAGEN
69 SNOMED-CT via HPO
70 TGDB
71 Tocris
72 UMLS
73 UMLS via Orphanet
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