Acute Pulmonary Heart Disease disease: Malacards - Research Articles, Drugs, Genes, Clinical Trials

Sources

Aliases & Classifications for Acute Pulmonary Heart Disease

MalaCards integrated aliases for Acute Pulmonary Heart Disease:

Name: Acute Pulmonary Heart Disease ¹² ¹⁵ ⁷⁴

Classifications:

MalaCards categories:
Anatomical: Cardiovascular diseases

See all MalaCards categories (disease lists)

External Ids:

Disease Ontology ¹² DOID:8514

ICD9CM ³⁶ 415

SNOMED-CT ⁶⁹ 67189007

UMLS ⁷⁴ C0155671

Sources

Summaries for Acute Pulmonary Heart Disease

MalaCards based summary : Acute Pulmonary Heart Disease is related to ligneous conjunctivitis and cardiogenic shock. An important gene associated with Acute Pulmonary Heart Disease is POR (Cytochrome P450 Oxidoreductase), and among its related pathways/superpathways are Response to elevated platelet cytosolic Ca2+ and Regulation of lipid metabolism Insulin signaling-generic cascades. The drugs Levodopa and Dopamine have been mentioned in the context of this disorder. Affiliated tissues include heart, and related phenotypes are cardiovascular system and cellular

Sources

Related Diseases for Acute Pulmonary Heart Disease

Diseases in the Acute Pulmonary Heart Disease family:

Chronic Pulmonary Heart Disease

Diseases related to Acute Pulmonary Heart Disease via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50) (show all 55)

#	Related Disease	Score	Top Affiliating Genes
1	ligneous conjunctivitis	10.4	PLAT PLG
2	cardiogenic shock	10.3	NPPB PLAT
3	anterolateral myocardial infarction	10.3	NPPB PLAT
4	central retinal artery occlusion	10.3	PLAT PLG
5	intestinal impaction	10.3	PLG SERPINF2
6	alpha-2-plasmin inhibitor deficiency	10.3	PLG SERPINF2
7	occlusion precerebral artery	10.3	PLAT PLG
8	giant hemangioma	10.3	PLG SERPINF2
9	basilar artery occlusion	10.3	PLAT PLG
10	acute poststreptococcal glomerulonephritis	10.3	PLG SERPINF2
11	platelet aggregation, spontaneous	10.3	PLAT SERPINF2
12	korean hemorrhagic fever	10.3	PLG SERPINF2
13	marantic endocarditis	10.3	PLAT SERPINF2
14	intermediate coronary syndrome	10.2	PLAT PLG
15	fibrinolytic defect	10.2	PLAT SERPINE1
16	inferior myocardial infarction	10.2	NPPB PLAT PLG
17	pregnancy adenoma	10.2	PLAT SERPINF2
18	tuberculous empyema	10.2	PLG SERPINE1
19	argentine hemorrhagic fever	10.2	PLAT SERPINE1
20	central serous chorioretinopathy	10.2	PLAT SERPINE1
21	pulmonary artery disease	10.2	PLAT PLG
22	blue toe syndrome	10.2	PLG SERPINE1
23	carotid artery thrombosis	10.2	PLAT SERPINE1
24	dysbaric osteonecrosis	10.2	PLG SERPINE1
25	angina pectoris	10.2	NPPB PLAT SERPINF2
26	intracranial embolism	10.2	PLAT PLG SERPINF2
27	pulmonary embolism and infarction	10.1	ADAM17 WDFY2
28	lemierre's syndrome	10.1	PLG SERPINE1
29	factor xiii deficiency	10.1	SERPINE1 SERPINF2
30	coronary thrombosis	10.1	PLAT SERPINE1
31	hepatic veno-occlusive disease	10.1	PLAT PLG SERPINE1
32	carotid artery dissection	10.1	PLAT PLG
33	coronary heart disease 1	10.1	NPPB PLAT SERPINE1
34	chronic venous insufficiency	10.0	PLAT SERPINE1
35	livedoid vasculitis	10.0	PLG SERPINE1 SERPINF2
36	plasminogen activator inhibitor-1 deficiency	10.0	PLAT SERPINE1 SERPINF2
37	venous insufficiency	10.0	PLAT SERPINE1
38	thrombophlebitis	10.0	PLAT SERPINE1 SERPINF2
39	tricuspid valve insufficiency	10.0	NPPB PDZK1IP1
40	disseminated intravascular coagulation	10.0	PLAT SERPINE1 SERPINF2
41	hemorrhagic disease	10.0	PLAT SERPINE1 SERPINF2
42	tricuspid valve disease	10.0	NPPB PDZK1IP1
43	hepatic vascular disease	10.0	ADAM17 PLG SERPINE1
44	mitral valve insufficiency	9.9	NPPB PDZK1IP1
45	arteries, anomalies of	9.9	NPPB PLAT PLG SERPINE1
46	coronary artery anomaly	9.9	NPPB PLAT PLG SERPINE1
47	brachial plexus lesion	9.9	CAMP WDFY2
48	pulmonary embolism	9.9	NPPB PLAT SERPINE1 SERPINF2
49	thrombophilia due to activated protein c resistance	9.9	PLAT PLG SERPINE1 SERPINF2
50	stroke, ischemic	9.8	PLAT PLG SERPINE1 SERPINF2

Graphical network of the top 20 diseases related to Acute Pulmonary Heart Disease:

Sources

Symptoms & Phenotypes for Acute Pulmonary Heart Disease

MGI Mouse Phenotypes related to Acute Pulmonary Heart Disease:

⁴⁷

#	Description	MGI Source Accession	Score	Top Affiliating Genes
1	cardiovascular system	MP:0005385	9.5	ADAM17 CAST PLAT PLG POR SERPINE1
2	cellular	MP:0005384	9.23	ADAM17 CAMP CAST PIWIL2 PLAT PLG

Sources

Drugs & Therapeutics for Acute Pulmonary Heart Disease

Drugs for Acute Pulmonary Heart Disease (from DrugBank, HMDB, Dgidb, PharmGKB, IUPHAR, NovoSeek, BitterDB):

(show all 20)

#

Name

Status

Phase

Clinical Trials

Cas Number

PubChem Id

1

Levodopa

Approved

59-92-7

6047

Synonyms:

(-)-(3,4-Dihydroxyphenyl)alanine

(−)-3-(3,4-dihydroxyphenyl)-L-alanine

(-)-3-(3,4-Dihydroxyphenyl)-L-alanine

(−)-dopa

(-)-Dopa

(2S)-2-amino-3-(3,4-Dihydroxyphenyl)propanoate

(2S)-2-amino-3-(3,4-dihydroxyphenyl)propanoic acid

(2S)-2-amino-3-(3,4-Dihydroxyphenyl)propanoic acid

.Beta.-(3, 4-Dihydroxyphenyl)alanine

.Beta.-(3,4-Dihydroxyphenyl)-L-alanine

1E83F927-C221-46AA-B90A-81B33C5F3868

23734-74-9

25525-15-9

2-Amino-3-(3,4-dihydroxyphenyl)propanoic acid

3 Hydroxy L tyrosine

3-(3,4-Dihydroxypheny

3-(3,4-Dihydroxyphenyl)-L-alanine

3, 4-Dihydroxy-L-phenylalanine

3, 4-Dihydroxyphenylalanine

3,4-dihydroxy-L-phenylalanine

3,4-Dihydroxy-L-phenylalanine

3,4-dihydroxyphenylalanine

3,4-Dihydroxyphenylalanine

3,4-DIHYDROXYPHENYLALANINE

3,4-Dihydroxyphenylalanine (VAN)

3,4-Dihydroxyphenyl-L-alanine

34241-25-3

37830_FLUKA

3-Hydroxy-L-tyrosine

587-45-1

59-92-7

72572-99-7

72573-00-3

88250-23-1

90638-38-3

AC-11686

AC1L1LOR

AC1Q4U7F

b-(3,4-Dihydroxyphenyl)-a-L-alanine

b-(3,4-Dihydroxyphenyl)alanine

b-(3,4-Dihydroxyphenyl)-L-alanine

Bendopa

beta-(3,4-Dihydroxyphenyl)alanine

beta-(3,4-Dihydroxyphenyl)-alpha-alanine

beta-(3,4-Dihydroxyphenyl)-alpha-L-alanine

beta-(3,4-Dihydroxyphenyl)-L-alanine

BIDD:GT0158

Bio-0575

Biodopa

bmse000322

BPBio1_000059

Brocadopa

BSPBio_000053

BSPBio_002354

C00355

C9H11NO4

CAS-59-92-7

CCRIS 3766

Cerepap

CHEBI:15765

CHEMBL1009

CID6047

Cidandopa

component of Sinemet

D 9628

D00059

D0600

D9628

D9628_SIGMA

DAH

DB01235

Deadopa

Dihydroxy-L-phenylalanine

Dihydroxyphenylalanine

DivK1c_000452

Dopa

DOPA

Dopaflex

Dopaidan

Dopal

Dopal-fher

Dopal-Fher

Dopalina

Dopar

Dopar (TN)

Doparkine

Doparl

Dopasol

Dopaston

Dopaston SE

Dopastone

Dopastral

Dopicar

Doprin

EINECS 200-445-2

Eldopal

Eldopar

Eldopatec

EU-0100454

Eurodopa

Helfo DOPA

helfo-Dopa

Helfo-Dopa

HMS1568C15

HMS1922J14

HMS2090O08

HMS2093N04

HMS501G14

HSDB 3348

IDI1_000452

InChI=1/C9H11NO4/c10-6(9(13)14)3-5-1-2-7(11)8(12)4-5/h1-2,4,6,11-12H,3,10H2,(H,13,14

Insulamina

IV Levodopa

KBio1_000452

KBio2_000934

KBio2_003502

KBio2_006070

KBioGR_001177

KBioSS_000934

L 3,4 Dihydroxyphenylalanine

L Dopa

L(-)-Dopa

L-(-)-Dopa

L-(3, 4-Dihydroxyphenyl)-.alpha.-alani

L-(3, 4-Dihydroxyphenyl)alanine

L-(o-Dihydroxyphenyl)alanine

l)-L-alanine

L-.Beta.-(3,4-Dihydroxyphenyl)alanine

L-3-(3,4-Dihydroxyphenyl)alanine

L-3-(3,4-Dihydroxyphenyl)-alanine

L-3,4-dihydroxyphenylalanine

L-3,4-Dihydroxyphenylalanine

L-3-Hydroxytyrosine

L-4-5-Dihydroxyphenylalanine

Laradopa

Larodopa

L-b-(3,4-Dihydroxyphenyl)-a-alanine

L-b-(3,4-Dihydroxyphenyl)alanine

L-beta-(3,4-Dihydroxyphenyl)alanine

L-beta-(3,4-Dihydroxyphenyl)-alpha-alanine

L-Dihydroxyphenylalanine

L-DOPA

L-DOPA, Parcopa, Atamet, Stalevo, Madopar, Prolopa, Dopar, 3,4-Dihydroxyphenylalanine, Levodopa

Ledopa

Levedopa

Levodopa

Levodopa (JP15/USP)

Levodopa (JP15/USP/INN)

Levodopa [USAN:INN:BAN:JAN]

Levodopum

Levodopum [INN-Latin]

Levopa

L-O-Dihydroxyphenylalanine

L-o-Hydroxytyrosine

Lopac0_000454

Lopac-D-9628

LS-255

L-β-(3,4-dihydroxyphenyl)alanine

Maipedopa

medphano Brand OF levodopa

MLS000028514

MolPort-000-856-937

NCGC00015384-01

NCGC00016270-01

NCGC00016270-06

NCGC00093869-04

nchembio.2007.55-comp26

nchembio.89-comp9

ne

NINDS_000452

NSC 118381

NSC118381

Parda

Pardopa

PDSP1_001541

PDSP2_001525

Prestwick_185

Prestwick0_000017

Prestwick1_000017

Prestwick2_000017

Prestwick3_000017

Prodopa

Ro 4-6316

Roberts brand OF levodopa

Roche brand OF levodopa

S1726_Selleck

SDCCGMLS-0066924.P001

SMR000058312

Sobiodopa

SPBio_000391

SPBio_001974

Spectrum_000454

Spectrum2_000496

SPECTRUM2300205

Spectrum4_000539

Spectrum5_001899

Syndopa

UNII-46627O600J

Veldopa

Weldopa

β-(3,4-dihydroxyphenyl)alanine

β-(3,4-dihydroxyphenyl)-L-alanine

2

Dopamine

Approved

62-31-7, 51-61-6

681

Synonyms:

(3H)-Dopamine

.alpha.-(3,4-Dihydroxyphenyl)-.beta.-aminoethane

.Beta.-(3,4-Dihydroxyphenyl)ethylamine hydrochloride

1,2-Benzenediol, 4-(2-aminoethyl)- (9CI)

1,2-Benzenediol, 4-(2-aminoethyl)-, hydrochloride

1,2-Benzenediol, 4-(2-aminoethyl)-, labeled with tritium

153C5321-5FEE-4B0B-8925-F388F0EEEBD1

2-(3,4-dihydroxyphenyl)ethylamine

2-(3,4-Dihydroxyphenyl)ethylamine

2-benzenediol

3,4 Dihydroxyphenethylamine

3,4-dihydroxyphenethylamine

3,4-Dihydroxyphenethylamine

3,4-Dihydroxyphenethylamine hydrochloride

3,4-Dihydroxyphenylethylamine

3-Hydroxtyramine

3-Hydroxytyramine

3-Hydroxytyramine Hydrobromide

3-Hydroxytyramine hydrochloride

4-(2-Aminoethyl)-1,

4-(2-aminoethyl)-1,2-benzenediol

4-(2-Aminoethyl)-1,2-benzenediol

4-(2-Aminoethyl)-1,2-bezenediol

4-(2-Aminoethyl)benzene-1,2-diol

4-(2-aminoethyl)catechol

4-(2-Aminoethyl)catechol

4-(2-aminoethyl)pyrocatechol

4-(2-aminoethyl)-pyrocatechol

4-(2-Aminoethyl)pyrocatechol

4-(2-Aminoethyl)-pyrocatechol

4-(2-Aminoethyl)pyrocatechol hydrochloride

50444-17-2

51-61-6

62-31-7 (HYDROCHLORIDE)

a-(3,4-Dihydroxyphenyl)-b-aminoethane

AC1L19S5

AC1Q54AX

AC1Q54AY

AKOS003790978

alpha-(3,4-Dihydroxyphenyl)-beta-aminoethane

ASL 279

BIDD:ER0506

Biomol-NT_000001

BPBio1_001123

BSPBio_001932

C03758

CHEBI:18243

CHEMBL59

CID681

cMAP_000036

cMAP_000065

D07870

DB00988

Deoxyepinephrine

DivK1c_000780

Dopamin

Dopamina

Dopamina [INN-Spanish]

dopamine

Dopamine

Dopamine (INN)

Dopamine (USAN)(*hydrochloride*)

Dopamine [INN:BAN]

Dopamine hydrochloride

Dopaminum

Dopaminum [INN-Latin]

Dopastat

Dophamine

Dynatra

EINECS 200-110-0

HSDB 3068

Hydrochloride, dopamine

Hydroxytyramin

hydroxytyramine

Hydroxytyramine

IDI1_000780

intropin

Intropin

Intropin [*hydrochloride*]

IP 498

KBio1_000780

KBio2_001492

KBio2_002388

KBio2_002484

KBio2_004060

KBio2_004956

KBio2_005052

KBio2_006628

KBio2_007524

KBio2_007620

KBio3_001152

KBio3_002867

KBio3_002962

KBioGR_001129

KBioGR_002388

KBioGR_002484

KBioSS_001492

KBioSS_002393

KBioSS_002491

KW-3-060

L000232

L-DOPAMINE

LDP

Lopac0_000586

Lopac-H-8502

LS-159

Medopa (TN)

m-Hydroxytyramine hydrochloride

MolPort-001-641-000

NCGC00015519-01

NCGC00015519-08

NCGC00096050-01

NCGC00096050-02

NCGC00096050-03

NCGC00096050-04

NCGC00096050-05

nchembio.105-comp9

nchembio.107-comp4

nchembio.284-comp1

nchembio.78-comp16

nchembio.89-comp3

nchembio705-8

nchembio801-comp8

NINDS_000780

NSC 173182

NSC169105

NSC173182

Oprea1_088821

Oxytyramine

Pyrocatechol, 4-(2-aminoethyl)- (8CI)

Pyrocatechol, 4-(2-aminoethyl)-, hydrochloride

Revimine

Revivan

SPBio_001205

Spectrum_001012

SPECTRUM1505155

Spectrum2_001023

Spectrum3_000406

Spectrum4_000525

Spectrum5_000945

ST048774

STK301601

UNII-VTD58H1Z2X

UPCMLD0ENAT5885989:001

3

Cabergoline

Approved

81409-90-7

54746

Synonyms:

(8b)-N-[3-(dimethylamino)Propyl]-N-[(ethylamino)carbonyl]-6-(2-propenyl)-ergoline-8-carboxamide

(8beta)-N-[3-(dimethylamino)propyl]-N-(ethylcarbamoyl)-6-(prop-2-en-1-yl)ergoline-8-carboxamide

(8beta)-N-[3-(dimethylamino)propyl]-N-[(ethylamino)carbonyl]-6-(2-propenyl)-ergoline-8-carboxamide

(8beta)-N-[3-(dimethylamino)Propyl]-N-[(ethylamino)carbonyl]-6-(2-propenyl)-ergoline-8-carboxamide

(8beta)-N-[3-(dimethylamino)propyl]-N-[(ethylamino)carbonyl]-6-prop-2-en-1-ylergoline-8-carboxamide

(8R)-6-allyl-N-[3-(dimethylamino)propyl]-N-(ethylcarbamoyl)ergoline-8-carboxamide

(8R)-6-Allyl-N-[3-(dimethylamino)propyl]-N-(ethylcarbamoyl)ergoline-8-carboxamide

(8β)-N-[3-(dimethylamino)propyl]-N-[(ethylamino)carbonyl]-6-(2-propenyl)-ergoline-8-carboxamide

1-((6-Allylergolin-8beta-yl)carbonyl)-1-(3-(dimethylamino)propyl)-3-ethylurea

1-((6-Allylergolin-8b-yl)carbonyl)-1-(3-(dimethylamino)propyl)-3-ethylurea

1-((6-allylergolin-8β-yl)carbonyl)-1-(3-(dimethylamino)propyl)-3-ethylurea

1-((6-Allylergolin-8β-yl)carbonyl)-1-(3-(dimethylamino)propyl)-3-ethylurea

1-[(6-allylergoline-8beta-yl)carbonyl]-1-[3-(dimethylamino)propyl]-3-ethylurea

1-[(6-Allylergoline-8beta-yl)carbonyl]-1-[3-(dimethylamino)propyl]-3-ethylurea

1-[(6-Allylergoline-8b-yl)carbonyl]-1-[3-(dimethylamino)propyl]-3-ethylurea

1-[(6-allylergoline-8β-yl)carbonyl]-1-[3-(dimethylamino)propyl]-3-ethylurea

1-[(6-Allylergoline-8β-yl)carbonyl]-1-[3-(dimethylamino)propyl]-3-ethylurea

1-ethyl-2-(3'-dimethylaminopropyl)-3-(6'-allylergoline-8'-beta-carbonyl)urea diphosphate

1-Ethyl-2-(3'-dimethylaminopropyl)-3-(6'-allylergoline-8'-beta-carbonyl)urea diphosphate

1-Ethyl-3-(3'-dimethylamionpropyl)-2-(6'-allylergoline-8'b-carbonyl)urea

1-ethyl-3-(3'-dimethylamionpropyl)-2-(6'-allylergoline-8'beta-carbonyl)urea

1-Ethyl-3-(3'-dimethylamionpropyl)-2-(6'-allylergoline-8'beta-carbonyl)urea

1-ethyl-3-(3'-dimethylamionpropyl)-2-(6'-allylergoline-8'β-carbonyl)urea

1-Ethyl-3-(3'-dimethylamionpropyl)-2-(6'-allylergoline-8'β-carbonyl)urea

81409-90-7

85329-89-1 (diphosphate)

AC-14150

AC1L1HO0

AC1Q5OQ0

BIDD:GT0775

BRD-K86882815-001-01-6

BRN 6020775

C08187

C26H37N5O2

Cabaser

Cabaser (TN)

Cabaseril

Cabergolina

Cabergolina [Spanish]

cabergoline

Cabergoline

Cabergoline (JAN/USAN/INN)

Cabergoline [USAN:BAN:INN]

Cabergoline diphosphate

Cabergolinum

Cabergolinum [Latin]

CG-101

CHEBI:3286

CHEMBL1201087

CID54746

D00987

DB00248

Dostinex

Dostinex (TN)

FCE-21336

FT-0081285

Galastop

HMS2090A09

LS-64370

MolPort-003-845-557

Sogilen

UNII-LL60K9J05T

4

Warfarin

Approved

81-81-2

54678486 6691

Synonyms:

(-)-Warfarin

(Phenyl-1 acetyl-2 ethyl) 3-hydroxy-4 coumarin

(Phenyl-1 acetyl-2 ethyl) 3-hydroxy-4 coumarine

(S)-4-Hydroxy-3-(3-oxo-1-phenylbutyl)-2-benzopyrone

(S)-Warfarin

1-(4'-Hydroxy-3'-coumarinyl)-1-phenyl-3-butanone

200 coumarin

200 Coumarin

3-(1'-Phenyl-2'-acetylethyl)-4-hydroxycoumarin

3-(Acetonylbenzyl)-4-hydroxycoumarin

3-(alpha-Acetonylbenzyl)-4-hydroxycoumarin

3-(alpha-Phenyl-beta-acetylaethyl)-4-hydroxycumarin

3-(alpha-Phenyl-beta-acetylethyl)-4-hydroxycoumarin

45706_FLUKA

45706_RIEDEL

4-Hydroxy-3- (3-oxo-1-fenyl-butyl) cumarine

4-Hydroxy-3- (3-oxo-1-phenyl-butyl)-cumarin

4-Hydroxy-3-(3-oxo-1-fenyl-butyl) cumarine

4-Hydroxy-3-(3-oxo-1-phenylbutyl)-2H-1-benzopyran-2-one

4-Hydroxy-3-(3-oxo-1-phenylbutyl)-2H-chromen-2-one

4-Hydroxy-3-(3-oxo-1-phenylbutyl)coumarin

4-Hydroxy-3-(3-oxo-1-phenyl-butyl)-cumarin

4-Idrossi-3- (3-oxo-)-fenil-butil)-cumarine

4-Idrossi-3-(3-oxo-)-fenil-butil)-cumarine

4-Idrossi-3-(3-oxo-1-fenil-butil)-cumarine

4oh-Coumarin deriv.

5543-56-6

5543-57-7

81-81-2

A2250_FLUKA

A2250_SIGMA

AC-15978

AC1L1N37

AC1Q6AN3

aldo Brand OF warfarin sodium

Aldocumar

Antigen brand OF warfarin sodium

Apotex brand OF warfarin sodium

apo-Warfarin

AR-1E2310

Arab rat death

Arab Rat Death

Arab rat deth

Athrombin

Athrombine-K

Athrombin-K

Bailly brand OF warfarin sodium

Bio-0586

Boots brand OF warfarin sodium

BRD-A24514565-001-02-2

BRD-A24514565-236-01-6

Bristol-myers squibb brand OF warfarin sodium

BRN 1293536

Brumolin

BSPBio_002026

C01541

C19H16O4

Caswell No. 903

CBDivE_002127

CBDivE_013236

CBKinase1_000192

CBKinase1_012592

CHEBI:10033

CHEMBL1464

Choice

Choice (TN)

CID6691

Compound 42

Co-Rax

CO-Rax

Coumadin

Coumadin Tabs

Coumadine

Coumafen

Coumafene

Coumafene [French]

Coumaphen

Coumaphene

Coumarins

Coumefene

Cov-R-tox

Cov-R-Tox

D08682

DB00682

D-Con

D-CON

delta-CON

Dethmor

Dethnel

Dicusat e

Dicusat E

DivK1c_000444

DL-3-(alpha-Acetonylbenzyl)-4-hydroxycoumarin

Eastern states duocide

EINECS 201-377-6

EINECS 226-907-3

EPA Pesticide Chemical Code 086002

Estedi brand OF warfarin sodium

fasco Fascrat powder

Fasco fascrat powder

Frass-ratron

Frass-Ratron

Genpharm brand OF warfarin sodium

Gen-warfarin

Goldshield brand OF warfarin sodium

HMS1921K07

HMS2092C20

HMS501G06

HSDB 1786

I14-0958

IDI1_000444

Jantoven

KBio1_000444

KBio2_000674

KBio2_003242

KBio2_005810

KBio3_001526

KBioGR_000901

KBioSS_000674

Killgerm sewarin P

Kumader

Kumadu

Kumatox

Kypfarin

Latka 42

Latka 42 [Czech]

Liqua-tox

LS-55083

Maag rattentod cum

Maag Rattentod Cum

Marevan

Mar-frin

Mar-Frin

Martin's mar-frin

Martin'S mar-frin

Maveran

MLS001304042

MolPort-001-787-822

Mouse pak

NCGC00094810-01

NCGC00094810-02

NCGC00159398-03

NCGC00178855-01

nchembio.307-comp19

NINDS_000444

NSC 59813

NSC59813

Panwarfin

Place-pax

Place-Pax

Potassium, warfarin

Prothromadin

PS104_SUPELCO

rac-Warfarin

Rat & mice bait

Rat and mice bait

Rat-alpha-way

Rat-a-way

Rat-beta-gon

Rat-b-gon

Rat-B-gon

Rat-gard

Rat-Gard

Rat-kill

Rat-Kill

Rat-mix

Rat-Mix

Rat-o-cide #2

Rat-O-cide #2

Rat-O-cide no. 2

Rat-ola

Rat-Ola

Ratorex

Ratox

Ratoxin

Ratron

Ratron g

Ratron G

Rats-no-more

Rats-NO-more

Ratten-koederrohr

Ratten-Koederrohr

Rattenstreupulver neu schacht

Rattenstreupulver Neu Schacht

Rattenstreupulver new schacht

Rattentraenke

Rat-trol

Rat-Trol

Rattunal

RAX

RCR Grey squirrel killer concentrate

RCRA waste no. P001

Rcra waste number P001

Rodafarin

Rodafarin c

Rodafarin C

ro-Deth

Ro-Deth

Rodex

Rodex blox

Rosex

Rough & ready mouse mix

Rough and ready mouse mix

Sakarat

Sewarin

SMP1_000316

SMR000718754

Sodium, warfarin

Sofarin

Solfarin

Sorexa plus

Sorexa Plus

SPBio_000870

Spectrum_000194

SPECTRUM1500613

Spectrum2_000935

Spectrum3_000583

Spectrum4_000381

Spectrum5_001751

Spray-trol brand roden-trol

STK364490

Tedicumar

Temus W

Tintorane

Tox-hid

Tox-Hid

Twin light rat away

UNII-5Q7ZVV76EI

Vampirinip II

Vampirinip iii

Vampirinip III

W.A.R.F. 42

Waran

Warf 10

Warf 42

WARF compound 42

Warfant

Warfarat

warfarin

Warfarin

Warfarin (and salts of)

Warfarin (INN)

Warfarin [BSI:ISO]

Warfarin [INN:BAN]

Warfarin plus

Warfarin Plus

Warfarin plus [discontinued]

Warfarin potassium

Warfarin Q

Warfarin sodium

Warfarin titrated to an INR of 2.5-3.0

Warfarin(R)

Warfarina

Warfarina [INN-Spanish]

Warfarine

Warfarine [INN-French]

Warfarine [ISO-French]

Warfarinum

Warfarinum [INN-Latin]

Warficide

Warfilone

WLN: T66 BOVJ DYR&1V1 EQ

Zoocoumarin

Zoocoumarin [Netherlands and USSR]

Zoocoumarin [Russian]

5

Serine

Approved, Nutraceutical

56-45-1

5951

Synonyms:

(-)-Serine

(2S)-2-amino-3-Hydroxypropanoate

(2S)-2-amino-3-Hydroxypropanoic acid

(S)-(-)-Serine

(S)-2-amino-3-Hydroxypropanoate

(S)-2-amino-3-Hydroxy-propanoate

(S)-2-amino-3-Hydroxypropanoic acid

(S)-2-amino-3-Hydroxy-propanoic acid

(S)-2-Amino-3-hydroxypropanoic acid

(S)-a-amino-b-Hydroxypropionate

(S)-a-amino-b-Hydroxypropionic acid

(S)-alpha-amino-beta-Hydroxypropionate

(S)-alpha-amino-beta-Hydroxypropionic acid

(S)-b-amino-3-Hydroxypropionate

(S)-b-amino-3-Hydroxypropionic acid

(S)-beta-amino-3-Hydroxypropionate

(S)-beta-amino-3-Hydroxypropionic acid

(S)-Serine

(S)-α-amino-β-hydroxypropionate

(S)-α-amino-β-hydroxypropionic acid

2-amino-3-Hydroxypropanoate

2-amino-3-Hydroxypropanoic acid

3-Hydroxy-L-alanine

alpha-Amino-beta-hydroxypropionic acid

beta-Hydroxyalanine

beta-Hydroxy-L-alanine

b-Hydroxyalanine

b-Hydroxy-L-alanine

L Serine

L-(-)-Serine

L-2-amino-3-Hydroxypropionate

L-2-amino-3-Hydroxypropionic acid

L-3-Hydroxy-2-aminopropionate

L-3-Hydroxy-2-aminopropionic acid

L-3-Hydroxy-alanine

L-Ser

L-Serin

L-Serine

S

Ser

Serina

Serine

SERINE

Serinum

β-hydroxyalanine

β-hydroxy-L-alanine

6

Dabigatran

Investigational

211914-51-1

7

Cardiotonic Agents

8

Sympathomimetics

9

Protective Agents

10

Peripheral Nervous System Agents

11

Neurotransmitter Agents

12

Dopamine agonists

13

Dopamine Agents

14

Autonomic Agents

15

protease inhibitors

16

Anticoagulants

17

HIV Protease Inhibitors

18

Antithrombin III

19

Antithrombins

20

Serine Proteinase Inhibitors

Interventional clinical trials:

#	Name	Status	NCT ID	Phase	Drugs
1	The Association Between Dopamine Agonists and Cardiac Valvulopathy, Fibrosis and Other Cardiopulmonary Events	Completed	NCT01052948
2	The Comparative Safety and Effectiveness of Warfarin and Dabigatran Prescribed in the Non-valvular Atrial Fibrillation Population With Humana Healthcare Coverage	Completed	NCT02061748		Observational

Search NIH Clinical Center for Acute Pulmonary Heart Disease

Sources

Genetic Tests for Acute Pulmonary Heart Disease

Sources

Anatomical Context for Acute Pulmonary Heart Disease

MalaCards organs/tissues related to Acute Pulmonary Heart Disease:

⁴²

Heart

Sources

Publications for Acute Pulmonary Heart Disease

Sources

Genes for Acute Pulmonary Heart Disease

Genes related to Acute Pulmonary Heart Disease (0 elite genes):

(show all 13)

- Elite gene

- Cancer Census gene in COSMIC

#	Symbol	Description	Category	Score	Evidence
1	POR	Cytochrome P450 Oxidoreductase	Protein Coding	15.1	DISEASES inferred ¹⁵
2	NPPB	Natriuretic Peptide B	Protein Coding	14.99	DISEASES inferred ¹⁵
3	PLG	Plasminogen	Protein Coding	14.97	DISEASES inferred ¹⁵
4	PLAT	Plasminogen Activator, Tissue Type	Protein Coding	14.62	DISEASES inferred ¹⁵
5	CAST	Calpastatin	Protein Coding	14.6	DISEASES inferred ¹⁵
6	VCL	Vinculin	Protein Coding	14.52	DISEASES inferred ¹⁵
7	SERPINF2	Serpin Family F Member 2	Protein Coding	14.2	DISEASES inferred ¹⁵
8	CAMP	Cathelicidin Antimicrobial Peptide	Protein Coding	14.12	DISEASES inferred ¹⁵
9	ADAM17	ADAM Metallopeptidase Domain 17	Protein Coding	13.3	DISEASES inferred ¹⁵
10	SERPINE1	Serpin Family E Member 1	Protein Coding	13.19	DISEASES inferred ¹⁵
11	PIWIL2	Piwi Like RNA-Mediated Gene Silencing 2	Protein Coding	5.35	DISEASES inferred ¹⁵
12	PDZK1IP1	PDZK1 Interacting Protein 1	Protein Coding	5.27	DISEASES inferred ¹⁵
13	WDFY2	WD Repeat And FYVE Domain Containing 2	Protein Coding	4.48	DISEASES inferred ¹⁵

Sources

Variations for Acute Pulmonary Heart Disease

Sources

Expression for Acute Pulmonary Heart Disease

Search GEO for disease gene expression data for Acute Pulmonary Heart Disease.

Sources

Pathways for Acute Pulmonary Heart Disease

Pathways related to Acute Pulmonary Heart Disease according to GeneCards Suite gene sharing:

#	Super pathways	Score	Top Affiliating Genes
1	Response to elevated platelet cytosolic Ca2+ ⁶⁷ Show member pathways Disinhibition of SNARE formation ⁶⁷ Hemostasis ⁶⁷ Platelet activation, signaling and aggregation ⁶⁷ Platelet degranulation ⁶⁷	12.95	PLAT PLG SERPINE1 SERPINF2 VCL
2	Regulation of lipid metabolism Insulin signaling-generic cascades ²³ Show member pathways acetyl-CoA biosynthesis from citrate ¹ Butyrate-induced histone acetylation ¹ Cell adhesion PLAU signaling ²³ Class IB PI3K non-lipid kinase events ¹ Development CNTF receptor signaling ²³ Development Growth hormone signaling via PI3K/AKT and MAPK cascades ²³ ErbB2/ErbB3 signaling events ¹ Glucose Homeostasis ¹ Insulin signaling pathway ³⁸ IRS activation ⁶⁷ Signal attenuation ⁶⁷ Transcription Receptor-mediated HIF regulation ²³ Translation Regulation of EIF2 activity ²³ Translation Regulation of EIF4F activity ²³ Translation Insulin regulation of translation ²³	12.53	ADAM17 PLAT PLG SERPINE1
3	Degradation of the extracellular matrix ⁶⁷ Show member pathways Collagen degradation ⁶⁷ Extracellular matrix organization ⁶⁷	12.36	ADAM17 CAST PLG SERPINE1
4	Selenium Micronutrient Network ¹ Show member pathways Folate Metabolism ¹ Metabolism of ingested MeSeO2H into MeSeH ⁶⁷ thioredoxin pathway ¹ Vitamin B12 Metabolism ¹	11.94	PLAT PLG SERPINE1
5	Formation of Fibrin Clot (Clotting Cascade) ⁶⁷ Show member pathways Blood Clotting Cascade ¹ Blood Coagulation Signaling Pathways ⁶⁶ Common Pathway of Fibrin Clot Formation ⁶⁷ Extrinsic Pathway of Fibrin Clot Formation ⁶⁷ Extrinsic Prothrombin Activation Pathway ⁶⁵ Intrinsic Pathway of Fibrin Clot Formation ⁶⁷	11.76	PLAT PLG SERPINE1 SERPINF2
6	Adhesion ⁴	11.63	PLG SERPINE1 VCL
7	Complement and coagulation cascades ¹ ³⁸	11.6	PLAT PLG SERPINE1 SERPINF2
8	Cell adhesion_ECM remodeling ²³	11.28	PLAT PLG SERPINE1
9	A-beta Pathways: Plaque Formation and APP Metabolism ⁶⁶	10.49	ADAM17 PLAT PLG
10	Dissolution of Fibrin Clot ⁶⁷	10.04	PLAT PLG SERPINE1 SERPINF2

Sources

GO Terms for Acute Pulmonary Heart Disease

Cellular components related to Acute Pulmonary Heart Disease according to GeneCards Suite gene sharing:

#	Name	GO ID	Score	Top Affiliating Genes
1	extracellular space	GO:0005615	9.8	CAMP NPPB PLAT PLG SERPINE1 SERPINF2
2	extracellular region	GO:0005576	9.8	CAMP NPPB PLAT PLG SERPINE1 SERPINF2
3	extracellular exosome	GO:0070062	9.7	CAMP PDZK1IP1 PLAT PLG SERPINE1 SERPINF2
4	cell surface	GO:0009986	9.67	ADAM17 PLAT PLG SERPINF2
5	collagen-containing extracellular matrix	GO:0062023	9.26	PLAT PLG SERPINE1 SERPINF2
6	platelet alpha granule lumen	GO:0031093	8.8	PLG SERPINE1 SERPINF2

Biological processes related to Acute Pulmonary Heart Disease according to GeneCards Suite gene sharing:

#	Name	GO ID	Score	Top Affiliating Genes
1	negative regulation of peptidase activity	GO:0010466	9.5	CAST SERPINE1 SERPINF2
2	platelet degranulation	GO:0002576	9.46	PLG SERPINE1 SERPINF2 VCL
3	negative regulation of plasminogen activation	GO:0010757	9.26	SERPINE1 SERPINF2
4	negative regulation of fibrinolysis	GO:0051918	9.13	PLG SERPINE1 SERPINF2
5	fibrinolysis	GO:0042730	8.92	PLAT PLG SERPINE1 SERPINF2

Molecular functions related to Acute Pulmonary Heart Disease according to GeneCards Suite gene sharing:

#	Name	GO ID	Score	Top Affiliating Genes
1	signaling receptor binding	GO:0005102	9.46	NPPB PLAT PLG SERPINE1
2	endopeptidase inhibitor activity	GO:0004866	9.26	CAST SERPINF2
3	peptidase inhibitor activity	GO:0030414	9.13	CAST SERPINE1 SERPINF2
4	protease binding	GO:0002020	8.8	CAST SERPINE1 SERPINF2

Sources

Sources for Acute Pulmonary Heart Disease

¹ BioSystems

² BitterDB

³ CDC

⁴ Cell Signaling Technology

⁵ ClinicalTrials

⁶ ClinVar

⁷ CNVD

⁸ Cochrane Library

⁹ Cosmic

¹⁰ dbSNP

¹¹ DGIdb

¹² Disease Ontology

¹³ diseasecard

¹⁴ DiseaseEnhancer

¹⁵ DISEASES

¹⁶ DrugBank

¹⁷ EFO

¹⁸ ExPASy

¹⁹ FDA Approved Drugs

²⁰ FMA

²¹ GeneAnalytics

²² GeneCards

²³ GeneGo (Thomson Reuters)

²⁴ GeneHancer via GeneCards

²⁵ GeneReviews

²⁶ Genetics Home Reference

²⁷ GenomeRNAi

²⁸ GEO DataSets

²⁹ GO

³⁰ GTR

³¹ HGMD

³² HMDB

³³ HPO

³⁴ ICD10

³⁵ ICD10 via Orphanet

³⁶ ICD9CM

³⁷ IUPHAR

³⁸ KEGG

³⁹ LifeMap

⁴⁰ LncRNADisease

⁴¹ LOVD

⁴² MalaCards

⁴³ MedGen

⁴⁴ MedlinePlus

⁴⁵ MeSH

⁴⁶ MESH via Orphanet

⁴⁷ MGI

⁴⁸ miR2Disease

⁴⁹ NCBI Bookshelf

⁵⁰ NCI

⁵¹ NCIt

⁵² NDF-RT

⁵³ NIH Clinical Center

⁵⁴ NIH Rare Diseases

⁵⁵ NINDS

⁵⁶ Novoseek

⁵⁷ Novus Biologicals

⁵⁸ OMIM

⁵⁹ OMIM via Orphanet

⁶⁰ Orphanet

⁶¹ PathCards

⁶² PharmGKB

⁶³ PubMed

⁶⁴ PubMed Health

⁶⁵ QIAGEN

⁶⁶ R&D Systems

⁶⁷ Reactome

⁶⁸ Sino Biological

⁶⁹ SNOMED-CT

⁷⁰ SNOMED-CT via HPO

⁷¹ SNOMED-CT via Orphanet

⁷² TGDB

⁷³ Tocris

⁷⁴ UMLS

⁷⁵ UMLS via Orphanet

⁷⁶ UniProtKB/Swiss-Prot

⁷⁷ Wikipedia