Acute Pulmonary Heart Disease disease: Malacards - Research Articles, Drugs, Genes, Clinical Trials

Sources

Aliases & Classifications for Acute Pulmonary Heart Disease

MalaCards integrated aliases for Acute Pulmonary Heart Disease:

Name: Acute Pulmonary Heart Disease ¹² ¹⁵ ⁷³

Classifications:

MalaCards categories:
Anatomical: Cardiovascular diseases

See all MalaCards categories (disease lists)

External Ids:

Disease Ontology ¹² DOID:8514

ICD9CM ³⁵ 415

SNOMED-CT ⁶⁸ 67189007

UMLS ⁷³ C0155671

Sources

Summaries for Acute Pulmonary Heart Disease

MalaCards based summary : Acute Pulmonary Heart Disease is related to ligneous conjunctivitis and cardiogenic shock. An important gene associated with Acute Pulmonary Heart Disease is EDEM1 (ER Degradation Enhancing Alpha-Mannosidase Like Protein 1), and among its related pathways/superpathways are Formation of Fibrin Clot (Clotting Cascade) and Adhesion. The drugs Cabergoline and Dopamine have been mentioned in the context of this disorder. Affiliated tissues include heart, and related phenotypes are digestive/alimentary and respiratory system

Sources

Related Diseases for Acute Pulmonary Heart Disease

Diseases in the Acute Pulmonary Heart Disease family:

Chronic Pulmonary Heart Disease

Diseases related to Acute Pulmonary Heart Disease via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50) (show all 51)

#	Related Disease	Score	Top Affiliating Genes
1	ligneous conjunctivitis	10.2	PLAT PLG
2	cardiogenic shock	10.2	NPPB PLAT
3	intestinal impaction	10.2	PLG SERPINF2
4	anterolateral myocardial infarction	10.2	NPPB PLAT
5	alpha-2-plasmin inhibitor deficiency	10.2	PLG SERPINF2
6	central retinal artery occlusion	10.2	PLAT PLG
7	giant hemangioma	10.2	PLG SERPINF2
8	acute poststreptococcal glomerulonephritis	10.2	PLG SERPINF2
9	platelet aggregation, spontaneous	10.2	PLAT SERPINF2
10	korean hemorrhagic fever	10.2	PLG SERPINF2
11	occlusion precerebral artery	10.2	PLAT PLG
12	basilar artery occlusion	10.2	PLAT PLG
13	marantic endocarditis	10.2	PLAT SERPINF2
14	fibrinolytic defect	10.2	PLAT SERPINE1
15	tuberculous empyema	10.2	PLG SERPINE1
16	argentine hemorrhagic fever	10.2	PLAT SERPINE1
17	central serous chorioretinopathy	10.2	PLAT SERPINE1
18	inferior myocardial infarction	10.1	NPPB PLAT PLG
19	blue toe syndrome	10.1	PLG SERPINE1
20	aspirin allergy	10.1	CA2 SERPINE1
21	pregnancy adenoma	10.1	PLAT SERPINF2
22	carotid artery thrombosis	10.1	PLAT SERPINE1
23	intracranial embolism	10.1	PLAT PLG SERPINF2
24	intermediate coronary syndrome	10.1	PLAT PLG
25	dysbaric osteonecrosis	10.1	PLG SERPINE1
26	pulmonary embolism and infarction	10.1	ADAM17 WDFY2
27	lemierre's syndrome	10.1	PLG SERPINE1
28	factor xiii deficiency	10.1	SERPINE1 SERPINF2
29	tricuspid valve insufficiency	10.1	NPPB PDZK1IP1
30	hepatic veno-occlusive disease	10.1	PLAT PLG SERPINE1
31	livedoid vasculitis	10.1	PLG SERPINE1 SERPINF2
32	plasminogen activator inhibitor-1 deficiency	10.1	PLAT SERPINE1 SERPINF2
33	thrombophlebitis	10.0	PLAT SERPINE1 SERPINF2
34	tricuspid valve disease	10.0	NPPB PDZK1IP1
35	disseminated intravascular coagulation	10.0	PLAT SERPINE1 SERPINF2
36	pulmonary artery disease	10.0	PLAT PLG
37	hemorrhagic disease	10.0	PLAT SERPINE1 SERPINF2
38	coronary heart disease 1	10.0	NPPB PLAT SERPINE1
39	hepatic vascular disease	10.0	ADAM17 PLG SERPINE1
40	coronary thrombosis	10.0	PLAT SERPINE1
41	mitral valve insufficiency	10.0	NPPB PDZK1IP1
42	arteries, anomalies of	10.0	NPPB PLAT PLG SERPINE1
43	coronary artery anomaly	10.0	NPPB PLAT PLG SERPINE1
44	pulmonary embolism	10.0	NPPB PLAT SERPINE1 SERPINF2
45	thrombophilia due to activated protein c resistance	10.0	PLAT PLG SERPINE1 SERPINF2
46	stroke, ischemic	9.9	PLAT PLG SERPINE1 SERPINF2
47	vein disease	9.9	ADAM17 PLAT PLG SERPINE1
48	chronic venous insufficiency	9.9	PLAT SERPINE1
49	acute myocardial infarction	9.9	NPPB PLAT PLG SERPINE1 SERPINF2
50	myocardial infarction	9.9	NPPB PLAT PLG SERPINE1 SERPINF2

Graphical network of the top 20 diseases related to Acute Pulmonary Heart Disease:

Sources

Symptoms & Phenotypes for Acute Pulmonary Heart Disease

MGI Mouse Phenotypes related to Acute Pulmonary Heart Disease:

⁴⁶

#	Description	MGI Source Accession	Score	Top Affiliating Genes
1	digestive/alimentary	MP:0005381	9.43	ADAM17 CA2 CREB3L2 PLAT PLG VCL
2	respiratory system	MP:0005388	9.1	ADAM17 CA2 PLAT PLG POR SERPINE1

Sources

Drugs & Therapeutics for Acute Pulmonary Heart Disease

Drugs for Acute Pulmonary Heart Disease (from DrugBank, HMDB, Dgidb, PharmGKB, IUPHAR, NovoSeek, BitterDB):

(show all 20)

#

Name

Status

Phase

Clinical Trials

Cas Number

PubChem Id

1

Cabergoline

Approved

81409-90-7

54746

Synonyms:

(8b)-N-[3-(dimethylamino)Propyl]-N-[(ethylamino)carbonyl]-6-(2-propenyl)-ergoline-8-carboxamide

(8beta)-N-[3-(dimethylamino)propyl]-N-(ethylcarbamoyl)-6-(prop-2-en-1-yl)ergoline-8-carboxamide

(8beta)-N-[3-(dimethylamino)propyl]-N-[(ethylamino)carbonyl]-6-(2-propenyl)-ergoline-8-carboxamide

(8beta)-N-[3-(dimethylamino)Propyl]-N-[(ethylamino)carbonyl]-6-(2-propenyl)-ergoline-8-carboxamide

(8beta)-N-[3-(dimethylamino)propyl]-N-[(ethylamino)carbonyl]-6-prop-2-en-1-ylergoline-8-carboxamide

(8R)-6-allyl-N-[3-(dimethylamino)propyl]-N-(ethylcarbamoyl)ergoline-8-carboxamide

(8R)-6-Allyl-N-[3-(dimethylamino)propyl]-N-(ethylcarbamoyl)ergoline-8-carboxamide

(8β)-N-[3-(dimethylamino)propyl]-N-[(ethylamino)carbonyl]-6-(2-propenyl)-ergoline-8-carboxamide

1-((6-Allylergolin-8beta-yl)carbonyl)-1-(3-(dimethylamino)propyl)-3-ethylurea

1-((6-Allylergolin-8b-yl)carbonyl)-1-(3-(dimethylamino)propyl)-3-ethylurea

1-((6-Allylergolin-8β-yl)carbonyl)-1-(3-(dimethylamino)propyl)-3-ethylurea

1-[(6-allylergoline-8beta-yl)carbonyl]-1-[3-(dimethylamino)propyl]-3-ethylurea

1-[(6-Allylergoline-8beta-yl)carbonyl]-1-[3-(dimethylamino)propyl]-3-ethylurea

1-[(6-Allylergoline-8b-yl)carbonyl]-1-[3-(dimethylamino)propyl]-3-ethylurea

1-[(6-Allylergoline-8β-yl)carbonyl]-1-[3-(dimethylamino)propyl]-3-ethylurea

1-ethyl-2-(3'-dimethylaminopropyl)-3-(6'-allylergoline-8'-beta-carbonyl)urea diphosphate

1-Ethyl-2-(3'-dimethylaminopropyl)-3-(6'-allylergoline-8'-beta-carbonyl)urea diphosphate

1-Ethyl-3-(3'-dimethylamionpropyl)-2-(6'-allylergoline-8'b-carbonyl)urea

1-ethyl-3-(3'-dimethylamionpropyl)-2-(6'-allylergoline-8'beta-carbonyl)urea

1-Ethyl-3-(3'-dimethylamionpropyl)-2-(6'-allylergoline-8'beta-carbonyl)urea

1-Ethyl-3-(3'-dimethylamionpropyl)-2-(6'-allylergoline-8'β-carbonyl)urea

81409-90-7

85329-89-1 (diphosphate)

AC-14150

AC1L1HO0

AC1Q5OQ0

BIDD:GT0775

BRD-K86882815-001-01-6

BRN 6020775

C08187

C26H37N5O2

Cabaser

Cabaser (TN)

Cabaseril

Cabergolina

Cabergolina [Spanish]

cabergoline

Cabergoline

Cabergoline (JAN/USAN/INN)

Cabergoline [USAN:BAN:INN]

Cabergoline diphosphate

Cabergolinum

Cabergolinum [Latin]

CG-101

CHEBI:3286

CHEMBL1201087

CID54746

D00987

DB00248

Dostinex

Dostinex (TN)

FCE-21336

FT-0081285

Galastop

HMS2090A09

LS-64370

MolPort-003-845-557

Sogilen

UNII-LL60K9J05T

2

Dopamine

Approved

51-61-6, 62-31-7

681

Synonyms:

(3H)-Dopamine

.alpha.-(3,4-Dihydroxyphenyl)-.beta.-aminoethane

.Beta.-(3,4-Dihydroxyphenyl)ethylamine hydrochloride

1,2-Benzenediol, 4-(2-aminoethyl)- (9CI)

1,2-Benzenediol, 4-(2-aminoethyl)-, hydrochloride

1,2-Benzenediol, 4-(2-aminoethyl)-, labeled with tritium

153C5321-5FEE-4B0B-8925-F388F0EEEBD1

2-(3,4-dihydroxyphenyl)ethylamine

2-(3,4-Dihydroxyphenyl)ethylamine

2-benzenediol

3,4 Dihydroxyphenethylamine

3,4-dihydroxyphenethylamine

3,4-Dihydroxyphenethylamine

3,4-Dihydroxyphenethylamine hydrochloride

3,4-Dihydroxyphenylethylamine

3-Hydroxtyramine

3-Hydroxytyramine

3-Hydroxytyramine Hydrobromide

3-Hydroxytyramine hydrochloride

4-(2-Aminoethyl)-1,

4-(2-aminoethyl)-1,2-benzenediol

4-(2-Aminoethyl)-1,2-benzenediol

4-(2-Aminoethyl)-1,2-bezenediol

4-(2-Aminoethyl)benzene-1,2-diol

4-(2-aminoethyl)catechol

4-(2-Aminoethyl)catechol

4-(2-aminoethyl)pyrocatechol

4-(2-aminoethyl)-pyrocatechol

4-(2-Aminoethyl)pyrocatechol

4-(2-Aminoethyl)-pyrocatechol

4-(2-Aminoethyl)pyrocatechol hydrochloride

50444-17-2

51-61-6

62-31-7 (HYDROCHLORIDE)

a-(3,4-Dihydroxyphenyl)-b-aminoethane

AC1L19S5

AC1Q54AX

AC1Q54AY

AKOS003790978

alpha-(3,4-Dihydroxyphenyl)-beta-aminoethane

ASL 279

BIDD:ER0506

Biomol-NT_000001

BPBio1_001123

BSPBio_001932

C03758

CHEBI:18243

CHEMBL59

CID681

cMAP_000036

cMAP_000065

D07870

DB00988

Deoxyepinephrine

DivK1c_000780

Dopamin

Dopamina

Dopamina [INN-Spanish]

dopamine

Dopamine

Dopamine (INN)

Dopamine (USAN)(*hydrochloride*)

Dopamine [INN:BAN]

Dopamine hydrochloride

Dopaminum

Dopaminum [INN-Latin]

Dopastat

Dophamine

Dynatra

EINECS 200-110-0

HSDB 3068

Hydrochloride, dopamine

Hydroxytyramin

hydroxytyramine

Hydroxytyramine

IDI1_000780

intropin

Intropin

Intropin [*hydrochloride*]

IP 498

KBio1_000780

KBio2_001492

KBio2_002388

KBio2_002484

KBio2_004060

KBio2_004956

KBio2_005052

KBio2_006628

KBio2_007524

KBio2_007620

KBio3_001152

KBio3_002867

KBio3_002962

KBioGR_001129

KBioGR_002388

KBioGR_002484

KBioSS_001492

KBioSS_002393

KBioSS_002491

KW-3-060

L000232

L-DOPAMINE

LDP

Lopac0_000586

Lopac-H-8502

LS-159

Medopa (TN)

m-Hydroxytyramine hydrochloride

MolPort-001-641-000

NCGC00015519-01

NCGC00015519-08

NCGC00096050-01

NCGC00096050-02

NCGC00096050-03

NCGC00096050-04

NCGC00096050-05

nchembio.105-comp9

nchembio.107-comp4

nchembio.284-comp1

nchembio.78-comp16

nchembio.89-comp3

nchembio705-8

nchembio801-comp8

NINDS_000780

NSC 173182

NSC169105

NSC173182

Oprea1_088821

Oxytyramine

Pyrocatechol, 4-(2-aminoethyl)- (8CI)

Pyrocatechol, 4-(2-aminoethyl)-, hydrochloride

Revimine

Revivan

SPBio_001205

Spectrum_001012

SPECTRUM1505155

Spectrum2_001023

Spectrum3_000406

Spectrum4_000525

Spectrum5_000945

ST048774

STK301601

UNII-VTD58H1Z2X

UPCMLD0ENAT5885989:001

3

Levodopa

Approved

59-92-7

6047

Synonyms:

(-)-(3,4-Dihydroxyphenyl)alanine

(−)-3-(3,4-dihydroxyphenyl)-L-alanine

(-)-3-(3,4-Dihydroxyphenyl)-L-alanine

(−)-dopa

(-)-Dopa

(2S)-2-amino-3-(3,4-Dihydroxyphenyl)propanoate

(2S)-2-amino-3-(3,4-dihydroxyphenyl)propanoic acid

(2S)-2-amino-3-(3,4-Dihydroxyphenyl)propanoic acid

.Beta.-(3, 4-Dihydroxyphenyl)alanine

.Beta.-(3,4-Dihydroxyphenyl)-L-alanine

1E83F927-C221-46AA-B90A-81B33C5F3868

23734-74-9

25525-15-9

2-Amino-3-(3,4-dihydroxyphenyl)propanoic acid

3 Hydroxy L tyrosine

3-(3,4-Dihydroxypheny

3-(3,4-Dihydroxyphenyl)-L-alanine

3, 4-Dihydroxy-L-phenylalanine

3, 4-Dihydroxyphenylalanine

3,4-dihydroxy-L-phenylalanine

3,4-Dihydroxy-L-phenylalanine

3,4-dihydroxyphenylalanine

3,4-Dihydroxyphenylalanine

3,4-DIHYDROXYPHENYLALANINE

3,4-Dihydroxyphenylalanine (VAN)

3,4-Dihydroxyphenyl-L-alanine

34241-25-3

37830_FLUKA

3-Hydroxy-L-tyrosine

587-45-1

59-92-7

72572-99-7

72573-00-3

88250-23-1

90638-38-3

AC-11686

AC1L1LOR

AC1Q4U7F

b-(3,4-Dihydroxyphenyl)-a-L-alanine

b-(3,4-Dihydroxyphenyl)alanine

b-(3,4-Dihydroxyphenyl)-L-alanine

Bendopa

beta-(3,4-Dihydroxyphenyl)alanine

beta-(3,4-Dihydroxyphenyl)-alpha-alanine

beta-(3,4-Dihydroxyphenyl)-alpha-L-alanine

beta-(3,4-Dihydroxyphenyl)-L-alanine

BIDD:GT0158

Bio-0575

Biodopa

bmse000322

BPBio1_000059

Brocadopa

BSPBio_000053

BSPBio_002354

C00355

C9H11NO4

CAS-59-92-7

CCRIS 3766

Cerepap

CHEBI:15765

CHEMBL1009

CID6047

Cidandopa

component of Sinemet

D 9628

D00059

D0600

D9628

D9628_SIGMA

DAH

DB01235

Deadopa

Dihydroxy-L-phenylalanine

Dihydroxyphenylalanine

DivK1c_000452

Dopa

DOPA

Dopaflex

Dopaidan

Dopal

Dopal-fher

Dopal-Fher

Dopalina

Dopar

Dopar (TN)

Doparkine

Doparl

Dopasol

Dopaston

Dopaston SE

Dopastone

Dopastral

Dopicar

Doprin

EINECS 200-445-2

Eldopal

Eldopar

Eldopatec

EU-0100454

Eurodopa

Helfo DOPA

helfo-Dopa

Helfo-Dopa

HMS1568C15

HMS1922J14

HMS2090O08

HMS2093N04

HMS501G14

HSDB 3348

IDI1_000452

InChI=1/C9H11NO4/c10-6(9(13)14)3-5-1-2-7(11)8(12)4-5/h1-2,4,6,11-12H,3,10H2,(H,13,14

Insulamina

IV Levodopa

KBio1_000452

KBio2_000934

KBio2_003502

KBio2_006070

KBioGR_001177

KBioSS_000934

L 3,4 Dihydroxyphenylalanine

L Dopa

L(-)-Dopa

L-(-)-Dopa

L-(3, 4-Dihydroxyphenyl)-.alpha.-alani

L-(3, 4-Dihydroxyphenyl)alanine

L-(o-Dihydroxyphenyl)alanine

l)-L-alanine

L-.Beta.-(3,4-Dihydroxyphenyl)alanine

L-3-(3,4-Dihydroxyphenyl)alanine

L-3-(3,4-Dihydroxyphenyl)-alanine

L-3,4-dihydroxyphenylalanine

L-3,4-Dihydroxyphenylalanine

L-3-Hydroxytyrosine

L-4-5-Dihydroxyphenylalanine

Laradopa

Larodopa

L-b-(3,4-Dihydroxyphenyl)-a-alanine

L-b-(3,4-Dihydroxyphenyl)alanine

L-beta-(3,4-Dihydroxyphenyl)alanine

L-beta-(3,4-Dihydroxyphenyl)-alpha-alanine

L-Dihydroxyphenylalanine

L-DOPA

L-DOPA, Parcopa, Atamet, Stalevo, Madopar, Prolopa, Dopar, 3,4-Dihydroxyphenylalanine, Levodopa

Ledopa

Levedopa

Levodopa

Levodopa (JP15/USP)

Levodopa (JP15/USP/INN)

Levodopa [USAN:INN:BAN:JAN]

Levodopum

Levodopum [INN-Latin]

Levopa

L-O-Dihydroxyphenylalanine

L-o-Hydroxytyrosine

Lopac0_000454

Lopac-D-9628

LS-255

L-β-(3,4-dihydroxyphenyl)alanine

Maipedopa

medphano Brand OF levodopa

MLS000028514

MolPort-000-856-937

NCGC00015384-01

NCGC00016270-01

NCGC00016270-06

NCGC00093869-04

nchembio.2007.55-comp26

nchembio.89-comp9

ne

NINDS_000452

NSC 118381

NSC118381

Parda

Pardopa

PDSP1_001541

PDSP2_001525

Prestwick_185

Prestwick0_000017

Prestwick1_000017

Prestwick2_000017

Prestwick3_000017

Prodopa

Ro 4-6316

Roberts brand OF levodopa

Roche brand OF levodopa

S1726_Selleck

SDCCGMLS-0066924.P001

SMR000058312

Sobiodopa

SPBio_000391

SPBio_001974

Spectrum_000454

Spectrum2_000496

SPECTRUM2300205

Spectrum4_000539

Spectrum5_001899

Syndopa

UNII-46627O600J

Veldopa

Weldopa

β-(3,4-dihydroxyphenyl)alanine

β-(3,4-dihydroxyphenyl)-L-alanine

4

Warfarin

Approved

81-81-2

6691 54678486

Synonyms:

(-)-Warfarin

(Phenyl-1 acetyl-2 ethyl) 3-hydroxy-4 coumarin

(Phenyl-1 acetyl-2 ethyl) 3-hydroxy-4 coumarine

(S)-4-Hydroxy-3-(3-oxo-1-phenylbutyl)-2-benzopyrone

(S)-Warfarin

1-(4'-Hydroxy-3'-coumarinyl)-1-phenyl-3-butanone

200 coumarin

200 Coumarin

3-(1'-Phenyl-2'-acetylethyl)-4-hydroxycoumarin

3-(Acetonylbenzyl)-4-hydroxycoumarin

3-(alpha-Acetonylbenzyl)-4-hydroxycoumarin

3-(alpha-Phenyl-beta-acetylaethyl)-4-hydroxycumarin

3-(alpha-Phenyl-beta-acetylethyl)-4-hydroxycoumarin

45706_FLUKA

45706_RIEDEL

4-Hydroxy-3- (3-oxo-1-fenyl-butyl) cumarine

4-Hydroxy-3- (3-oxo-1-phenyl-butyl)-cumarin

4-Hydroxy-3-(3-oxo-1-fenyl-butyl) cumarine

4-Hydroxy-3-(3-oxo-1-phenylbutyl)-2H-1-benzopyran-2-one

4-Hydroxy-3-(3-oxo-1-phenylbutyl)-2H-chromen-2-one

4-Hydroxy-3-(3-oxo-1-phenylbutyl)coumarin

4-Hydroxy-3-(3-oxo-1-phenyl-butyl)-cumarin

4-Idrossi-3- (3-oxo-)-fenil-butil)-cumarine

4-Idrossi-3-(3-oxo-)-fenil-butil)-cumarine

4-Idrossi-3-(3-oxo-1-fenil-butil)-cumarine

4oh-Coumarin deriv.

5543-56-6

5543-57-7

81-81-2

A2250_FLUKA

A2250_SIGMA

AC-15978

AC1L1N37

AC1Q6AN3

aldo Brand OF warfarin sodium

Aldocumar

Antigen brand OF warfarin sodium

Apotex brand OF warfarin sodium

apo-Warfarin

AR-1E2310

Arab rat death

Arab Rat Death

Arab rat deth

Athrombin

Athrombine-K

Athrombin-K

Bailly brand OF warfarin sodium

Bio-0586

Boots brand OF warfarin sodium

BRD-A24514565-001-02-2

BRD-A24514565-236-01-6

Bristol-myers squibb brand OF warfarin sodium

BRN 1293536

Brumolin

BSPBio_002026

C01541

C19H16O4

Caswell No. 903

CBDivE_002127

CBDivE_013236

CBKinase1_000192

CBKinase1_012592

CHEBI:10033

CHEMBL1464

Choice

Choice (TN)

CID6691

Compound 42

Co-Rax

CO-Rax

Coumadin

Coumadin Tabs

Coumadine

Coumafen

Coumafene

Coumafene [French]

Coumaphen

Coumaphene

Coumarins

Coumefene

Cov-R-tox

Cov-R-Tox

D08682

DB00682

D-Con

D-CON

delta-CON

Dethmor

Dethnel

Dicusat e

Dicusat E

DivK1c_000444

DL-3-(alpha-Acetonylbenzyl)-4-hydroxycoumarin

Eastern states duocide

EINECS 201-377-6

EINECS 226-907-3

EPA Pesticide Chemical Code 086002

Estedi brand OF warfarin sodium

fasco Fascrat powder

Fasco fascrat powder

Frass-ratron

Frass-Ratron

Genpharm brand OF warfarin sodium

Gen-warfarin

Goldshield brand OF warfarin sodium

HMS1921K07

HMS2092C20

HMS501G06

HSDB 1786

I14-0958

IDI1_000444

Jantoven

KBio1_000444

KBio2_000674

KBio2_003242

KBio2_005810

KBio3_001526

KBioGR_000901

KBioSS_000674

Killgerm sewarin P

Kumader

Kumadu

Kumatox

Kypfarin

Latka 42

Latka 42 [Czech]

Liqua-tox

LS-55083

Maag rattentod cum

Maag Rattentod Cum

Marevan

Mar-frin

Mar-Frin

Martin's mar-frin

Martin'S mar-frin

Maveran

MLS001304042

MolPort-001-787-822

Mouse pak

NCGC00094810-01

NCGC00094810-02

NCGC00159398-03

NCGC00178855-01

nchembio.307-comp19

NINDS_000444

NSC 59813

NSC59813

Panwarfin

Place-pax

Place-Pax

Potassium, warfarin

Prothromadin

PS104_SUPELCO

rac-Warfarin

Rat & mice bait

Rat and mice bait

Rat-alpha-way

Rat-a-way

Rat-beta-gon

Rat-b-gon

Rat-B-gon

Rat-gard

Rat-Gard

Rat-kill

Rat-Kill

Rat-mix

Rat-Mix

Rat-o-cide #2

Rat-O-cide #2

Rat-O-cide no. 2

Rat-ola

Rat-Ola

Ratorex

Ratox

Ratoxin

Ratron

Ratron g

Ratron G

Rats-no-more

Rats-NO-more

Ratten-koederrohr

Ratten-Koederrohr

Rattenstreupulver neu schacht

Rattenstreupulver Neu Schacht

Rattenstreupulver new schacht

Rattentraenke

Rat-trol

Rat-Trol

Rattunal

RAX

RCR Grey squirrel killer concentrate

RCRA waste no. P001

Rcra waste number P001

Rodafarin

Rodafarin c

Rodafarin C

ro-Deth

Ro-Deth

Rodex

Rodex blox

Rosex

Rough & ready mouse mix

Rough and ready mouse mix

Sakarat

Sewarin

SMP1_000316

SMR000718754

Sodium, warfarin

Sofarin

Solfarin

Sorexa plus

Sorexa Plus

SPBio_000870

Spectrum_000194

SPECTRUM1500613

Spectrum2_000935

Spectrum3_000583

Spectrum4_000381

Spectrum5_001751

Spray-trol brand roden-trol

STK364490

Tedicumar

Temus W

Tintorane

Tox-hid

Tox-Hid

Twin light rat away

UNII-5Q7ZVV76EI

Vampirinip II

Vampirinip iii

Vampirinip III

W.A.R.F. 42

Waran

Warf 10

Warf 42

WARF compound 42

Warfant

Warfarat

warfarin

Warfarin (and salts of)

Warfarin (INN)

Warfarin [BSI:ISO]

Warfarin [INN:BAN]

Warfarin plus

Warfarin Plus

Warfarin plus [discontinued]

Warfarin potassium

Warfarin Q

Warfarin sodium

Warfarin titrated to an INR of 2.5-3.0

Warfarin(R)

Warfarina

Warfarina [INN-Spanish]

Warfarine

Warfarine [INN-French]

Warfarine [ISO-French]

Warfarinum

Warfarinum [INN-Latin]

Warficide

Warfilone

WLN: T66 BOVJ DYR&1V1 EQ

Zoocoumarin

Zoocoumarin [Netherlands and USSR]

Zoocoumarin [Russian]

5

Serine

Approved, Nutraceutical

56-45-1

5951

Synonyms:

(-)-Serine

(2S)-2-amino-3-Hydroxypropanoate

(2S)-2-amino-3-Hydroxypropanoic acid

(S)-(-)-Serine

(S)-2-amino-3-Hydroxypropanoate

(S)-2-amino-3-Hydroxy-propanoate

(S)-2-amino-3-Hydroxypropanoic acid

(S)-2-amino-3-Hydroxy-propanoic acid

(S)-2-Amino-3-hydroxypropanoic acid

(S)-a-amino-b-Hydroxypropionate

(S)-a-amino-b-Hydroxypropionic acid

(S)-alpha-amino-beta-Hydroxypropionate

(S)-alpha-amino-beta-Hydroxypropionic acid

(S)-b-amino-3-Hydroxypropionate

(S)-b-amino-3-Hydroxypropionic acid

(S)-beta-amino-3-Hydroxypropionate

(S)-beta-amino-3-Hydroxypropionic acid

(S)-Serine

(S)-α-amino-β-hydroxypropionate

(S)-α-amino-β-hydroxypropionic acid

2-amino-3-Hydroxypropanoate

2-amino-3-Hydroxypropanoic acid

3-Hydroxy-L-alanine

alpha-Amino-beta-hydroxypropionic acid

beta-Hydroxyalanine

beta-Hydroxy-L-alanine

b-Hydroxyalanine

b-Hydroxy-L-alanine

L Serine

L-(-)-Serine

L-2-amino-3-Hydroxypropionate

L-2-amino-3-Hydroxypropionic acid

L-3-Hydroxy-2-aminopropionate

L-3-Hydroxy-2-aminopropionic acid

L-3-Hydroxy-alanine

L-Ser

L-Serin

L-Serine

S

Ser

Serina

SERINE

Serinum

β-hydroxyalanine

β-hydroxy-L-alanine

6

Dopamine Agents

7

Peripheral Nervous System Agents

8

Sympathomimetics

9

Dopamine agonists

10

Cardiotonic Agents

11

Protective Agents

12

Autonomic Agents

13

Neurotransmitter Agents

14

protease inhibitors

15

Anticoagulants

16

Antithrombins

17

Antithrombin III

18

HIV Protease Inhibitors

19

Serine Proteinase Inhibitors

20

Dabigatran

Interventional clinical trials:

#	Name	Status	NCT ID	Phase	Drugs
1	The Association Between Dopamine Agonists and Cardiac Valvulopathy, Fibrosis and Other Cardiopulmonary Events	Completed	NCT01052948
2	The Comparative Safety and Effectiveness of Warfarin and Dabigatran Prescribed in the Non-valvular Atrial Fibrillation Population With Humana Healthcare Coverage	Completed	NCT02061748		Observational

Search NIH Clinical Center for Acute Pulmonary Heart Disease

Sources

Genetic Tests for Acute Pulmonary Heart Disease

Sources

Anatomical Context for Acute Pulmonary Heart Disease

MalaCards organs/tissues related to Acute Pulmonary Heart Disease:

⁴¹

Heart

Sources

Publications for Acute Pulmonary Heart Disease

Sources

Genes for Acute Pulmonary Heart Disease

Genes related to Acute Pulmonary Heart Disease (0 elite genes):

(show all 16)

- Elite gene

- Cancer Census gene in COSMIC

#	Symbol	Description	Category	Score	Evidence
1	EDEM1	ER Degradation Enhancing Alpha-Mannosidase Like Protein 1	Protein Coding	15.94	DISEASES inferred ¹⁵
2	POR	Cytochrome P450 Oxidoreductase	Protein Coding	15.37	DISEASES inferred ¹⁵
3	DESI2	Desumoylating Isopeptidase 2	Protein Coding	15.27	DISEASES inferred ¹⁵
4	NPPB	Natriuretic Peptide B	Protein Coding	14.89	DISEASES inferred ¹⁵
5	PLG	Plasminogen	Protein Coding	14.84	DISEASES inferred ¹⁵
6	VCL	Vinculin	Protein Coding	14.42	DISEASES inferred ¹⁵
7	PLAT	Plasminogen Activator, Tissue Type	Protein Coding	14.41	DISEASES inferred ¹⁵
8	SERPINF2	Serpin Family F Member 2	Protein Coding	14.07	DISEASES inferred ¹⁵
9	CAMP	Cathelicidin Antimicrobial Peptide	Protein Coding	14.02	DISEASES inferred ¹⁵
10	CA2	Carbonic Anhydrase 2	Protein Coding	13.83	DISEASES inferred ¹⁵
11	ADAM17	ADAM Metallopeptidase Domain 17	Protein Coding	13.22	DISEASES inferred ¹⁵
12	SERPINE1	Serpin Family E Member 1	Protein Coding	13.07	DISEASES inferred ¹⁵
13	PIWIL2	Piwi Like RNA-Mediated Gene Silencing 2	Protein Coding	5.27	DISEASES inferred ¹⁵
14	PDZK1IP1	PDZK1 Interacting Protein 1	Protein Coding	5.18	DISEASES inferred ¹⁵
15	CREB3L2	CAMP Responsive Element Binding Protein 3 Like 2	Protein Coding	4.69	DISEASES inferred ¹⁵
16	WDFY2	WD Repeat And FYVE Domain Containing 2	Protein Coding	4.38	DISEASES inferred ¹⁵

Sources

Variations for Acute Pulmonary Heart Disease

Sources

Expression for Acute Pulmonary Heart Disease

Search GEO for disease gene expression data for Acute Pulmonary Heart Disease.

Sources

Pathways for Acute Pulmonary Heart Disease

Pathways related to Acute Pulmonary Heart Disease according to GeneCards Suite gene sharing:

#	Super pathways	Score	Top Affiliating Genes
1	Formation of Fibrin Clot (Clotting Cascade) ⁶⁶ Show member pathways Blood Clotting Cascade ¹ Blood Coagulation Signaling Pathways ⁶⁵ Common Pathway of Fibrin Clot Formation ⁶⁶ Extrinsic Pathway of Fibrin Clot Formation ⁶⁶ Extrinsic Prothrombin Activation Pathway ⁶⁴ Intrinsic Pathway of Fibrin Clot Formation ⁶⁶	11.76	PLAT PLG SERPINE1 SERPINF2
2	Adhesion ⁴	11.63	PLG SERPINE1 VCL
3	Complement and coagulation cascades ¹ ³⁷	11.6	PLAT PLG SERPINE1 SERPINF2
4	Cell adhesion_ECM remodeling ²²	11.28	PLAT PLG SERPINE1
5	A-beta Pathways: Plaque Formation and APP Metabolism ⁶⁵	10.49	ADAM17 PLAT PLG
6	Dissolution of Fibrin Clot ⁶⁶	10.04	PLAT PLG SERPINE1 SERPINF2

Sources

GO Terms for Acute Pulmonary Heart Disease

Cellular components related to Acute Pulmonary Heart Disease according to GeneCards Suite gene sharing:

#	Name	GO ID	Score	Top Affiliating Genes
1	extracellular space	GO:0005615	9.8	CA2 CAMP NPPB PLAT PLG SERPINE1
2	extracellular exosome	GO:0070062	9.56	CA2 CAMP PDZK1IP1 PLAT PLG SERPINE1
3	collagen-containing extracellular matrix	GO:0062023	9.46	PLAT PLG SERPINE1 SERPINF2
4	platelet alpha granule lumen	GO:0031093	8.8	PLG SERPINE1 SERPINF2

Biological processes related to Acute Pulmonary Heart Disease according to GeneCards Suite gene sharing:

#	Name	GO ID	Score	Top Affiliating Genes
1	platelet degranulation	GO:0002576	9.46	PLG SERPINE1 SERPINF2 VCL
2	morphogenesis of an epithelium	GO:0002009	9.32	CA2 VCL
3	negative regulation of plasminogen activation	GO:0010757	9.26	SERPINE1 SERPINF2
4	negative regulation of fibrinolysis	GO:0051918	9.13	PLG SERPINE1 SERPINF2
5	fibrinolysis	GO:0042730	8.92	PLAT PLG SERPINE1 SERPINF2

Molecular functions related to Acute Pulmonary Heart Disease according to GeneCards Suite gene sharing:

#	Name	GO ID	Score	Top Affiliating Genes
1	signaling receptor binding	GO:0005102	9.26	NPPB PLAT PLG SERPINE1
2	hydrolase activity	GO:0016787	9.17	ADAM17 DESI2 EDEM1 PIWIL2 PLAT PLG

Sources

Sources for Acute Pulmonary Heart Disease

¹ BioSystems

² BitterDB

³ CDC

⁴ Cell Signaling Technology

⁵ ClinicalTrials

⁶ ClinVar

⁷ CNVD

⁸ Cochrane Library

⁹ Cosmic

¹⁰ dbSNP

¹¹ DGIdb

¹² Disease Ontology

¹³ diseasecard

¹⁴ DiseaseEnhancer

¹⁵ DISEASES

¹⁶ DrugBank

¹⁷ ExPASy

¹⁸ FDA Approved Drugs

¹⁹ FMA

²⁰ GeneAnalytics

²¹ GeneCards

²² GeneGo (Thomson Reuters)

²³ GeneHancer via GeneCards

²⁴ GeneReviews

²⁵ Genetics Home Reference

²⁶ GenomeRNAi

²⁷ GEO DataSets

²⁸ GO

²⁹ GTR

³⁰ HGMD

³¹ HMDB

³² HPO

³³ ICD10

³⁴ ICD10 via Orphanet

³⁵ ICD9CM

³⁶ IUPHAR

³⁷ KEGG

³⁸ LifeMap

³⁹ LncRNADisease

⁴⁰ LOVD

⁴¹ MalaCards

⁴² MedGen

⁴³ MedlinePlus

⁴⁴ MeSH

⁴⁵ MESH via Orphanet

⁴⁶ MGI

⁴⁷ miR2Disease

⁴⁸ NCBI Bookshelf

⁴⁹ NCI

⁵⁰ NCIt

⁵¹ NDF-RT

⁵² NIH Clinical Center

⁵³ NIH Rare Diseases

⁵⁴ NINDS

⁵⁵ Novoseek

⁵⁶ Novus Biologicals

⁵⁷ OMIM

⁵⁸ OMIM via Orphanet

⁵⁹ Orphanet

⁶⁰ PathCards

⁶¹ PharmGKB

⁶² PubMed

⁶³ PubMed Health

⁶⁴ QIAGEN

⁶⁵ R&D Systems

⁶⁶ Reactome

⁶⁷ Sino Biological

⁶⁸ SNOMED-CT

⁶⁹ SNOMED-CT via HPO

⁷⁰ SNOMED-CT via Orphanet

⁷¹ TGDB

⁷² Tocris

⁷³ UMLS

⁷⁴ UMLS via Orphanet

⁷⁵ UniProtKB/Swiss-Prot

⁷⁶ Wikipedia