Acute Pulmonary Heart Disease disease: Malacards - Research Articles, Drugs, Genes, Clinical Trials

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Aliases & Classifications for Acute Pulmonary Heart Disease

MalaCards integrated aliases for Acute Pulmonary Heart Disease:

Name: Acute Pulmonary Heart Disease ¹² ¹⁵ ⁷¹

Classifications:

MalaCards categories:
Anatomical: Cardiovascular diseases

See all MalaCards categories (disease lists)

External Ids:

Disease Ontology ¹² DOID:8514

ICD9CM ³⁴ 415

SNOMED-CT ⁶⁷ 67189007

UMLS ⁷¹ C0155671

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Summaries for Acute Pulmonary Heart Disease

MalaCards based summary : Acute Pulmonary Heart Disease is related to pulmonary embolism and acute cor pulmonale. An important gene associated with Acute Pulmonary Heart Disease is PDZK1IP1 (PDZK1 Interacting Protein 1), and among its related pathways/superpathways are Formation of Fibrin Clot (Clotting Cascade) and Complement and coagulation cascades. Affiliated tissues include heart.

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Related Diseases for Acute Pulmonary Heart Disease

Diseases in the Acute Pulmonary Heart Disease family:

Chronic Pulmonary Heart Disease

Diseases related to Acute Pulmonary Heart Disease via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50) (show all 88)

#	Related Disease	Score	Top Affiliating Genes
1	pulmonary embolism	30.2	PLAT NPPB F3
2	acute cor pulmonale	26.6	ZSCAN32 WBP2NL PLG PLAT PIWIL2 PDZK1IP1
3	heart disease	10.4
4	cardiogenic shock	10.3	PLAT NPPB
5	anterolateral myocardial infarction	10.3	PLAT NPPB
6	pulmonary valve disease	10.3	PDZK1IP1 NPPB
7	lujo hemorrhagic fever	10.3	NPPB F3
8	aortic valve insufficiency	10.2	PDZK1IP1 NPPB
9	ligneous conjunctivitis	10.2	PLG PLAT
10	anterior cerebral artery infarction	10.2	PLG PLAT
11	mitral valve insufficiency	10.2	PDZK1IP1 NPPB
12	basilar artery occlusion	10.2	PLG PLAT
13	basal ganglia cerebrovascular disease	10.2	PLG PLAT
14	thoracic outlet syndrome	10.2	PLG PLAT
15	vertebral artery occlusion	10.2	PLG PLAT
16	brain stem infarction	10.2	PLG PLAT
17	carotid artery thrombosis	10.2	PLAT F3
18	medulloadrenal hyperfunction	10.2	PLG F3
19	conversion disorder	10.2	PLG PLAT
20	hereditary angioedema with normal c1inh	10.2	PLG PLAT
21	middle cerebral artery infarction	10.1	PLG PLAT
22	central retinal artery occlusion	10.1	PLG PLAT
23	intracranial sinus thrombosis	10.1	PLG F3
24	encephalopathy, familial, with neuroserpin inclusion bodies	10.1	PLG PLAT
25	hemopericardium	10.1	PLG F3
26	leech infestation	10.1	PLG F3
27	obstructive hydrocephalus	10.1	PLG PLAT
28	sagittal sinus thrombosis	10.1	PLG F3
29	facial nerve disease	10.1	PLG PLAT
30	carotid artery occlusion	10.1	PLG PLAT
31	pericardium disease	10.1	NPPB F3
32	alpha-2-plasmin inhibitor deficiency	10.1	PLG F3
33	pericardial effusion	10.1	PDZK1IP1 NPPB F3
34	mitral valve disease	10.1	PDZK1IP1 NPPB F3
35	compartment syndrome	10.1	PLG F3
36	constrictive pericarditis	10.0	WBP2NL NPPB
37	antithrombin iii deficiency	10.0	PLG F3
38	autoimmune disease of cardiovascular system	10.0	PLG F3
39	angina pectoris	10.0	PLAT NPPB F3
40	critical illness polyneuropathy	10.0	WBP2NL F3
41	inferior myocardial infarction	10.0	PLG PLAT NPPB
42	thrombophilia due to thrombin defect	10.0	PLAT F3
43	inherited blood coagulation disease	10.0	PLG F3
44	intracranial hypertension	10.0	NPPB F3
45	endocardium disease	10.0	PLG F3
46	marantic endocarditis	9.9	PLG PLAT F3
47	cerebral falx meningioma	9.9	PLG PLAT F3
48	hepatic vascular disease	9.9	PLG F3
49	intracranial embolism	9.9	PLG PLAT F3
50	posterior cerebral artery infarction	9.9	PLG PLAT F3

Graphical network of the top 20 diseases related to Acute Pulmonary Heart Disease:

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Symptoms & Phenotypes for Acute Pulmonary Heart Disease

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Drugs & Therapeutics for Acute Pulmonary Heart Disease

Search Clinical Trials , NIH Clinical Center for Acute Pulmonary Heart Disease

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Genetic Tests for Acute Pulmonary Heart Disease

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Anatomical Context for Acute Pulmonary Heart Disease

MalaCards organs/tissues related to Acute Pulmonary Heart Disease:

⁴⁰

Heart

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Publications for Acute Pulmonary Heart Disease

Articles related to Acute Pulmonary Heart Disease:

(show all 16)

#	Title	Authors	PMID	Year
1	[Acute pulmonary heart disease caused by pulmonary artery embolism]. ⁶¹	Heintzen MP...Strauer BE	10429913	1999
2	[The value of transesophageal echocardiography for the diagnosis of pulmonary embolism with acute pulmonary heart disease]. ⁶¹	Antakly-Hanon Y...Dubourg O	9749175	1998
3	[Massive pulmonary artery embolism complicated by acute pulmonary heart disease]. ⁶¹	Kober J...Pawlicka L	9181893	1996
4	[Structural and metabolic changes in the contractile myocardium in experimental acute pulmonary heart disease of vascular origin]. ⁶¹	Vinogradov SA...Kolbasin PN	7159237	1982
5	[Acute pulmonary heart disease in a person with chronic bronchopneumopathy and secondary heart disease. Uhlenbruck's syndrome]. ⁶¹	Chini V	4693710	1973
6	[Acute pulmonary heart disease in resuscitation: case reports]. ⁶¹	Castelli E...Mastrorilli M	4807138	1973
7	[A case of intermittent and transitory complete right branch block in embolic acute pulmonary heart disease]. ⁶¹	Warembourg H...Peltier JM	5138704	1971
8	[Acute pulmonary heart disease induced by repeated pulmonary embolisms. Embolectomy under extracorporeal circulation]. ⁶¹	Lemoine G...Mathey J	5778506	1969
9	[ACUTE PULMONARY HEART DISEASE DUE TO AMNIOTIC EMBOLISM. EXPERIMENTAL STUDY]. ⁶¹	MOINE C...MARION P	14289703	1965
10	[ACUTE PULMONARY HEART DISEASE. II. PULMONARY EMBOLISM]. ⁶¹	ERNST S	14251093	1964
11	[Various aspects of acute pulmonary heart disease caused by thromboembolism; doctrinal concept and antecedents]. ⁶¹	SORRIBES-SANTAMARIA V	13358395	1956
12	[Pulmonary embolism and acute pulmonary heart disease; study of the syndrome and analysis of an observation]. ⁶¹	BEAUCHESNE A	13308177	1955
13	[Acute pulmonary heart disease]. ⁶¹	FAIVRE G	14359694	1955
14	[Surgical indications in acute pulmonary heart disease caused by pulmonary embolism]. ⁶¹	TOURNIAIRE A...DEYRIEUX F	13195717	1954
15	[Study on a cardiac output in acute pulmonary heart disease]. ⁶¹	FAIVRE G...HUEBER J	13178378	1954
16	[Acute pulmonary heart disease in serious asthma; therapy and cure]. ⁶¹	DUSSERT A	13226252	1954

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Genes for Acute Pulmonary Heart Disease

Genes related to Acute Pulmonary Heart Disease (0 elite genes):

(show all 11)

- Elite gene

- Cancer Census gene in COSMIC

#	Symbol	Description	Category	Score	Evidence
1	PDZK1IP1	PDZK1 Interacting Protein 1	Protein Coding	6.03	DISEASES inferred ¹⁵
2	OR2H2	Olfactory Receptor Family 2 Subfamily H Member 2	Protein Coding	5.62	DISEASES inferred ¹⁵
3	NPPB	Natriuretic Peptide B	Protein Coding	5.34	DISEASES inferred ¹⁵
4	PLAT	Plasminogen Activator, Tissue Type	Protein Coding	5.28	DISEASES inferred ¹⁵
5	ZSCAN32	Zinc Finger And SCAN Domain Containing 32	Protein Coding	5.15	DISEASES inferred ¹⁵
6	F3	Coagulation Factor III, Tissue Factor	Protein Coding	5.15	DISEASES inferred ¹⁵
7	PLG	Plasminogen	Protein Coding	5.1	DISEASES inferred ¹⁵
8	PEAK3	PEAK Family Member 3	Protein Coding	4.73	DISEASES inferred ¹⁵
9	WBP2NL	WBP2 N-Terminal Like	Protein Coding	4.69	DISEASES inferred ¹⁵
10	PIWIL2	Piwi Like RNA-Mediated Gene Silencing 2	Protein Coding	4.66	DISEASES inferred ¹⁵
11	SCARNA9	Small Cajal Body-Specific RNA 9	RNA Gene	4.65	DISEASES inferred ¹⁵

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Variations for Acute Pulmonary Heart Disease

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Expression for Acute Pulmonary Heart Disease

Search GEO for disease gene expression data for Acute Pulmonary Heart Disease.

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Pathways for Acute Pulmonary Heart Disease

Pathways related to Acute Pulmonary Heart Disease according to GeneCards Suite gene sharing:

#	Super pathways	Score	Top Affiliating Genes
1	Formation of Fibrin Clot (Clotting Cascade) ⁶⁵ Show member pathways Blood Clotting Cascade ¹ Blood Coagulation Signaling Pathways ⁶⁴ Common Pathway of Fibrin Clot Formation ⁶⁵ Extrinsic Pathway of Fibrin Clot Formation ⁶⁵ Extrinsic Prothrombin Activation Pathway ⁶³ Intrinsic Pathway of Fibrin Clot Formation ⁶⁵	11.53	PLG PLAT F3
2	Complement and coagulation cascades ³⁶ ¹	11.29	PLG PLAT F3
3	Cell adhesion_Plasmin signaling ²²	11.06	PLG PLAT
4	amb2 Integrin signaling ¹	11	PLG PLAT
5	A-beta Plaque Formation and APP Metabolism ⁶⁴	10.62	PLG PLAT
6	Dissolution of Fibrin Clot ⁶⁵	9.74	PLG PLAT

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GO Terms for Acute Pulmonary Heart Disease

Biological processes related to Acute Pulmonary Heart Disease according to GeneCards Suite gene sharing:

#	Name	GO ID	Score	Top Affiliating Genes
1	blood coagulation	GO:0007596	9.33	PLG PLAT F3
2	hemostasis	GO:0007599	9.26	PLG F3
3	fibrinolysis	GO:0042730	8.96	PLG PLAT
4	trans-synaptic signaling by BDNF, modulating synaptic transmission	GO:0099183	8.62	PLG PLAT

Molecular functions related to Acute Pulmonary Heart Disease according to GeneCards Suite gene sharing:

#	Name	GO ID	Score	Top Affiliating Genes
1	serine-type endopeptidase activity	GO:0004252	8.8	PLG PLAT F3

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Sources for Acute Pulmonary Heart Disease

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