MCID: ACT038
MIFTS: 27

Acute Retrobulbar Neuritis

Categories: Eye diseases, Neuronal diseases

Aliases & Classifications for Acute Retrobulbar Neuritis

MalaCards integrated aliases for Acute Retrobulbar Neuritis:

Name: Acute Retrobulbar Neuritis 12 15 71
Retrobulbar Neuritis 12 71

Classifications:



External Ids:

Disease Ontology 12 DOID:14155
ICD9CM 34 377.32
SNOMED-CT 67 51604006
ICD10 32 H48.1
UMLS 71 C0085582 C0155301

Summaries for Acute Retrobulbar Neuritis

MalaCards based summary : Acute Retrobulbar Neuritis, also known as retrobulbar neuritis, is related to optic neuritis and neuritis. An important gene associated with Acute Retrobulbar Neuritis is MT-ND4 (Mitochondrially Encoded NADH:Ubiquinone Oxidoreductase Core Subunit 4). Affiliated tissues include eye, testes and brain.

Related Diseases for Acute Retrobulbar Neuritis

Diseases related to Acute Retrobulbar Neuritis via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50) (show all 122)
# Related Disease Score Top Affiliating Genes
1 optic neuritis 32.6 MT-ND4 MBP AQP4
2 neuritis 30.8 MT-ND4 MBP AQP4
3 scotoma 30.8 MT-ND4 AQP4
4 nutritional optic neuropathy 30.2 MT-ND4 BLOC1S6
5 optic papillitis 30.1 CD40LG AQP4
6 myelitis 29.6 MBP CD40LG AQP4
7 demyelinating disease 29.6 MBP CD40LG AQP4
8 guillain-barre syndrome 29.6 MBP CD40LG
9 meningoencephalitis 29.4 MBP CD40LG
10 optic nerve disease 28.6 MT-ND4 MBP CD40LG BLOC1S6 AQP4
11 multiple sclerosis 10.5
12 toxic optic neuropathy 10.3 MT-ND4 AQP4
13 combined oxidative phosphorylation deficiency 7 10.2 MT-ND4 AQP4
14 osteogenesis imperfecta, type xi 10.2 DNAI2 DNAI1
15 pfeiffer syndrome 10.2
16 meningioma, radiation-induced 10.2
17 meningioma, familial 10.2
18 spinal meningioma 10.2
19 secretory meningioma 10.2
20 lymphoplasmacyte-rich meningioma 10.2
21 exophthalmos 10.2
22 headache 10.2
23 3-methylglutaconic aciduria, type iii 10.2
24 herpes zoster 10.2
25 herpes zoster ophthalmicus 10.2
26 dextrocardia 10.1 DNAI2 DNAI1
27 branch retinal artery occlusion 10.1 BLOC1S6 AQP4
28 pernicious anemia 10.1
29 retinal detachment 10.1
30 factor xii deficiency 10.1
31 anemia, x-linked, with or without neutropenia and/or platelet abnormalities 10.1
32 kearns-sayre syndrome 10.1
33 malaria 10.1
34 deficiency anemia 10.1
35 asymptomatic neurosyphilis 10.1
36 mumps 10.1
37 suppression amblyopia 10.1
38 amblyopia 10.1
39 hemiplegia 10.1
40 uveitis 10.1
41 acquired immunodeficiency syndrome 10.1
42 cataract 10.1
43 meningitis 10.1
44 central serous chorioretinopathy 10.1
45 cluster headache 10.1
46 neurosyphilis 10.1
47 balo concentric sclerosis 10.1 MBP AQP4
48 autoimmune optic neuritis 10.1 MBP AQP4
49 internuclear ophthalmoplegia 10.1 MBP AQP4
50 transverse myelitis 10.1 MBP AQP4

Graphical network of the top 20 diseases related to Acute Retrobulbar Neuritis:



Diseases related to Acute Retrobulbar Neuritis

Symptoms & Phenotypes for Acute Retrobulbar Neuritis

Drugs & Therapeutics for Acute Retrobulbar Neuritis

Interventional clinical trials:


# Name Status NCT ID Phase Drugs
1 Utility of Quantification of Afferent Pupillary Defect in Predicting Optic Nerve Disease in Retrobulbar Neuritis, Multiple Sclerosis and Neuromyelitis Optica Spectrum Disease - a Retrospective and Prospective Analysis Enrolling by invitation NCT04131764

Search NIH Clinical Center for Acute Retrobulbar Neuritis

Genetic Tests for Acute Retrobulbar Neuritis

Anatomical Context for Acute Retrobulbar Neuritis

MalaCards organs/tissues related to Acute Retrobulbar Neuritis:

40
Eye, Testes, Brain, Retina, Heart, Monocytes, T Cells

Publications for Acute Retrobulbar Neuritis

Articles related to Acute Retrobulbar Neuritis:

(show top 50) (show all 421)
# Title Authors PMID Year
1
Strain and Shear Wave Elastography in Diagnosis of Retrobulbar Neuritis. 61
31022061 2020
2
Neuro-Ophthalmology at a Tertiary Eye Care Centre in India. 61
29135814 2018
3
Optic neuropathy and congenital glaucoma associated with probable Zika virus infection in Venezuelan patients. 61
29896405 2018
4
Ethambutol and isoniazid induced severe neurotoxicity in a patient undergoing continuous ambulatory peritoneal dialysis. 61
29776936 2018
5
[Issues of the current terminology in multiple sclerosis]. 61
30160680 2018
6
[Progression of nerve fiber layer defects in retrobulbar optic neuritis by the macular ganglion cell complex]. 61
29050924 2017
7
Visual complaints in intracranial germinomas. 61
28436607 2017
8
Clinical profile and neuroimaging in pediatric optic neuritis in Indian population: A case series. 61
28440255 2017
9
Vascular hypoperfusion in acute optic neuritis is a potentially new neurovascular model for demyelinating diseases. 61
28926646 2017
10
A case of retrobulbar optic neuritis caused by duloxetine. 61
26362493 2016
11
Neurological Manifestations of Brucellosis in an Indian Population. 61
27555982 2016
12
A rare adverse reaction to ethambutol: drug-induced haemolytic anaemia. 61
27084828 2016
13
Herpes zoster ophthalmicus with retrobulbar neuritis. 61
28242890 2016
14
Cytopathology of Vitreous Humor Samples in Routine Practice. 61
26986556 2016
15
Neuromyelitis Optica (NMO) with Abdominal Tuberculosis (TB). 61
26522188 2015
16
[Optic neuropathy after retrobulbar neuritis in multiple sclerosis: are optical coherence tomography and magnetic resonance imaging useful and necessary follow-up parameters?]. 61
25645891 2015
17
Visual pathways involvement in clinically isolated syndrome in children. 61
25938060 2015
18
Is the incidence of optic neuritis rising? Evidence from an epidemiological study in Barcelona (Spain), 2008-2012. 61
24532201 2014
19
Clinical profile and short-term outcomes of optic neuritis patients in India. 61
24722269 2014
20
[IgG4-related disease that presented cranial, cervical, lumbar and sacral hypertrophic pachymeningitis associated with infundibulo-hypophysitis]. 61
25142540 2014
21
Infectious and noninfectious granulomatosis in patient with multiple sclerosis: diagnostic dilemmas and followup. 61
25379311 2014
22
[Light sensitivity of the visual system in patients with demyelinating optic neuropathy in acute retrobulbar neuritis]. 61
24662356 2014
23
Orbital and optic nerve complications of inflammatory bowel disease. 61
23083697 2013
24
The primary vascular dysregulation syndrome: implications for eye diseases. 61
23742177 2013
25
The absence of vitreous inflammation: one more challenge in diagnosing toxoplasma papillitis. 61
23576658 2013
26
[Primary central nervous system lymphoma: a case report and evaluation of the diagnostic value of IL-10 level in the cerebrospinal fluid]. 61
23131747 2012
27
Idiopathic hypertrophic pachymeningitis presenting with a superficial soft tissue mass. 61
22865979 2012
28
Sphenoid sinus carcinoma mimicking retrobulbar optic neuritis. 61
22352827 2012
29
Monolateral visual loss due to cryptococcal meningitis. 61
21368010 2011
30
Bilateral retrobulbar neuritis in an adolescent boy with lymphoma. 61
21397810 2011
31
[Differential aspects of multiple sclerosis and chronic borrelial encephalomyelitis]. 61
21947065 2011
32
Case of acute zonal occult outer retinopathy with abnormal pattern visual evoked potentials. 61
21966193 2011
33
Mistaken diagnosis of optic neuritis and the possible role of phosphodiasterase-5 inhibitors (Sildenafil/Viagra). 61
21901956 2010
34
Bilateral Internuclear Ophthalmoplegia in a Patient with Devic's Neuromyelitis Optica. 61
21113284 2010
35
First manifestation of lambda positive plasmacytoma in the orbital apex with acute unilateral loss of vision. 61
20533138 2010
36
Influence of retrobulbar neuritis and papillitis on echographically measured optic nerve diameter. 61
20225632 2010
37
Immunoglobulin G4-related sclerosing sialadenitis: report of two cases and review of the literature. 61
19778741 2009
38
Aetiological treatment with itraconazole or ketoconazole in individuals with Trypanosoma cruzi/HIV co-infection. 61
19695152 2009
39
[Central scotoma and blurred vision in a patient with Crohn's disease]. 61
19440721 2009
40
Multiple cranial nerve involvement caused by Brucella melitensis. 61
19593297 2009
41
[Posterior ischaemic optic neuropathy]. 61
19579669 2009
42
Carboplatin-Induced Bilateral Papilledema: A Case Report. 61
20740148 2009
43
Chikungunya infection in children. 61
19330307 2009
44
[Nervous system disorders induced by occupational exposure to arsenic and its inorganic compounds: a literature review]. 61
20187500 2009
45
[Ocular bartonellosis in an HIV-HVC coinfected patient]. 61
18706780 2008
46
[Application of retinal nerves fiber layer examination--GDx in patients with multiple sclerosis]. 61
18669079 2008
47
Optic neuritis associated with chikungunya virus infection in South India. 61
17923547 2007
48
Ocular involvement associated with an epidemic outbreak of chikungunya virus infection. 61
17692276 2007
49
Wegener's granulomatosis and posterior ischemic optic neuropathy: Atypical associated conditions. 61
17574109 2007
50
Extensive meningoencephalitis, retrobulbar neuritis and pulmonary involvement in a patient of neurobrucellosis. 61
17558123 2007

Variations for Acute Retrobulbar Neuritis

Expression for Acute Retrobulbar Neuritis

Search GEO for disease gene expression data for Acute Retrobulbar Neuritis.

Pathways for Acute Retrobulbar Neuritis

GO Terms for Acute Retrobulbar Neuritis

Cellular components related to Acute Retrobulbar Neuritis according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 dynein complex GO:0030286 8.96 DNAI2 DNAI1
2 outer dynein arm GO:0036157 8.62 DNAI2 DNAI1

Biological processes related to Acute Retrobulbar Neuritis according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 cilium movement GO:0003341 8.96 DNAI2 DNAI1
2 outer dynein arm assembly GO:0036158 8.62 DNAI2 DNAI1

Molecular functions related to Acute Retrobulbar Neuritis according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 dynein heavy chain binding GO:0045504 8.96 DNAI2 DNAI1
2 dynein light chain binding GO:0045503 8.62 DNAI2 DNAI1

Sources for Acute Retrobulbar Neuritis

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
17 EFO
18 ExPASy
19 FMA
28 GO
29 GTR
30 HMDB
31 HPO
32 ICD10
33 ICD10 via Orphanet
34 ICD9CM
35 IUPHAR
36 KEGG
37 LifeMap
39 LOVD
41 MedGen
43 MeSH
44 MESH via Orphanet
45 MGI
48 NCI
49 NCIt
50 NDF-RT
53 NINDS
54 Novoseek
56 OMIM
57 OMIM via Orphanet
61 PubMed
63 QIAGEN
68 SNOMED-CT via HPO
69 TGDB
70 Tocris
71 UMLS
72 UMLS via Orphanet
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