MCID: ACT081
MIFTS: 38

Acute Salpingitis

Categories: Reproductive diseases

Aliases & Classifications for Acute Salpingitis

MalaCards integrated aliases for Acute Salpingitis:

Name: Acute Salpingitis 12 15 73

Classifications:



External Ids:

Disease Ontology 12 DOID:10973
ICD10 33 N70.01
NCIt 50 C40120
SNOMED-CT 68 8912009
UMLS 73 C0269038

Summaries for Acute Salpingitis

MalaCards based summary : Acute Salpingitis is related to salpingitis and acute salpingo-oophoritis. An important gene associated with Acute Salpingitis is TCOF1 (Treacle Ribosome Biogenesis Factor 1), and among its related pathways/superpathways are NF-KappaB Family Pathway and 4-1BB Pathway. Affiliated tissues include uterus, lung and skin, and related phenotypes are Synthetic lethal with MLN4924 (a NAE inhibitor) and Synthetic lethal with MLN4924 (a NAE inhibitor)

Related Diseases for Acute Salpingitis

Diseases in the Salpingitis family:

Acute Salpingitis Chronic Salpingitis

Diseases related to Acute Salpingitis via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50) (show all 66)
# Related Disease Score Top Affiliating Genes
1 salpingitis 31.6 OVGP1 TCOF1 TNF
2 acute salpingo-oophoritis 11.5
3 chlamydia 10.5
4 acute gonococcal salpingitis 10.2 CTSA TNF
5 posterior scleritis 10.2 MRAP TNF
6 retinitis pigmentosa 75 10.2 TNF TNFRSF1A
7 skin sarcoidosis 10.2 TNF TNFRSF1B
8 uveoparotid fever 10.2 LYZ TNF
9 iritis 10.2 MRAP TNFRSF1B
10 granulomatous dermatitis 10.2 TNF TNFRSF1B
11 rheumatoid lung disease 10.2 TNF TNFRSF1B
12 tenosynovitis 10.2 MRAP TNFRSF1B
13 inclusion conjunctivitis 10.2 MRAP OVGP1 TNF
14 relapsing fever 10.2 TNF TNFRSF1A
15 conjunctival disease 10.2 MRAP TNF TNFRSF1A
16 post-transplant lymphoproliferative disease 10.1 TNF TNFRSF1A TNFRSF1B
17 juvenile ankylosing spondylitis 10.1 MRAP TNF TNFRSF1B
18 scleral disease 10.1 MRAP TNF TNFRSF1B
19 pustulosis of palm and sole 10.1 MRAP TNF TNFRSF1B
20 fox-fordyce disease 10.1 CD68 MRAP
21 guillain-barre syndrome 10.1 TNF TNFRSF1A TNFRSF1B
22 panuveitis 10.1 MRAP TNF TNFRSF1B
23 dystrophinopathies 10.1 TNF TNFRSF1A
24 uveal disease 10.1 MRAP TNF TNFRSF1B
25 spondyloarthropathy 1 10.1 MRAP TNF TNFRSF1B
26 bone inflammation disease 10.1 MRAP TNF TNFRSF1B
27 central nervous system sarcoma 10.1 CD68 LYZ
28 cardiomyopathy, infantile histiocytoid 10.1 CD68 LYZ
29 malignant giant cell tumor of soft parts 10.1 CD68 LYZ
30 orbital plasma cell granuloma 10.1 MME MRAP TNFRSF1B
31 chronic orbital inflammation 10.1 MME MRAP TNFRSF1B
32 adult xanthogranuloma 10.1 CD68 LYZ
33 balloon cell malignant melanoma 10.1 CD68 MME
34 peroneal neuropathy 10.1 MME TNF TNFRSF1B
35 rhinoscleroma 10.1 CD68 TNFRSF1B
36 sciatic neuropathy 10.1 TNFRSF1A TNFRSF1B
37 microscopic colitis 10.1 LYZ TNF
38 psoriatic arthritis 10.1 TNF TNFRSF1A TNFRSF1B
39 erythema elevatum diutinum 10.1 CD68 TNFRSF1B
40 osgood-schlatter's disease 10.1 MEG8 MRAP
41 pericoronitis 10.1 CD68 TNFRSF1A TNFRSF1B
42 liver sarcoma 10.1 CD68 LYZ
43 leukocyte disease 10.1 MCL1 MME TNF
44 t-cell/histiocyte rich large b cell lymphoma 10.1 CD68 MME
45 palindromic rheumatism 10.1 MRAP TNF TNFRSF1A TNFRSF1B
46 trigeminal nerve neoplasm 10.1 CD68 LYZ
47 inflamed seborrheic keratosis 10.1 CD68 CLEC2A
48 behcet syndrome 10.0 MRAP TNF TNFRSF1A TNFRSF1B
49 diffuse infiltrative lymphocytosis syndrome 10.0 MRAP TNF
50 melkersson-rosenthal syndrome 10.0 CD68 TNF TNFRSF1B

Graphical network of the top 20 diseases related to Acute Salpingitis:



Diseases related to Acute Salpingitis

Symptoms & Phenotypes for Acute Salpingitis

GenomeRNAi Phenotypes related to Acute Salpingitis according to GeneCards Suite gene sharing:

26
# Description GenomeRNAi Source Accession Score Top Affiliating Genes
1 Synthetic lethal with MLN4924 (a NAE inhibitor) GR00250-A-1 9.72 HRK MCL1 TCOF1 TNF TNFRSF1A TNFRSF1B
2 Synthetic lethal with MLN4924 (a NAE inhibitor) GR00250-A-2 9.72 HRK MCL1 TCOF1 TNF TNFRSF1A TNFRSF1B

MGI Mouse Phenotypes related to Acute Salpingitis:

46
# Description MGI Source Accession Score Top Affiliating Genes
1 hematopoietic system MP:0005397 10.02 BAK1 BLK CD68 CTSA CXCL13 LYZ
2 immune system MP:0005387 10 BAK1 BLK CD68 CTSA CXCL13 LYZ
3 endocrine/exocrine gland MP:0005379 9.97 BAK1 BLK LYZ MCL1 TCOF1 TNF
4 integument MP:0010771 9.7 CTSA LYZ MCL1 MME TNF TNFRSF1A
5 liver/biliary system MP:0005370 9.43 CTSA LYZ MME TNF TNFRSF1A TNFRSF1B
6 reproductive system MP:0005389 9.23 BAK1 BLK CTSA LYZ MCL1 OVGP1

Drugs & Therapeutics for Acute Salpingitis

Search Clinical Trials , NIH Clinical Center for Acute Salpingitis

Genetic Tests for Acute Salpingitis

Anatomical Context for Acute Salpingitis

MalaCards organs/tissues related to Acute Salpingitis:

41
Uterus, Lung, Skin, Liver, Bone, T Cells, B Cells

Publications for Acute Salpingitis

Articles related to Acute Salpingitis:

(show top 50) (show all 103)
# Title Authors Year
1
Acute Salpingitis in a Nonsexually Active Adolescent. ( 26626893 )
2015
2
Ultrastructure damage of oviduct telocytes in rat model of acute salpingitis. ( 25753567 )
2015
3
Ultrasound for diagnosing acute salpingitis: a prospective observational diagnostic study. ( 23503942 )
2013
4
Effect of human immunodeficiency virus-1 infection on treatment outcome of acute salpingitis. ( 16582116 )
2006
5
Detection of Mycoplasma genitalium in women with laparoscopically diagnosed acute salpingitis. ( 16326847 )
2005
6
Viable intrauterine pregnancy with acute salpingitis progressing to septic abortion. A case report. ( 12497692 )
2002
7
Picture of the month. Transvaginal sonographic image of acute salpingitis. ( 11309184 )
2001
8
Laparoscopic and microbiological features of acute salpingitis in developing countries. ( 15512039 )
1998
9
Effect of human immunodeficiency virus type 1 infection upon acute salpingitis: a laparoscopic study. ( 9780255 )
1998
10
A study of second-look laparoscopy after acute salpingitis. ( 8844136 )
1996
11
Clinical, laparoscopic and microbiological findings in acute salpingitis: report on a United Kingdom cohort. ( 7612536 )
1995
12
Observations concerning the microbial etiology of acute salpingitis. ( 8166184 )
1994
13
Post-therapeutic evolution of serum chlamydial antibody titers in women with acute salpingitis and tubal infertility. ( 8034076 )
1994
14
Detection of Chlamydia trachomatis by the polymerase chain reaction in the cervices of women with acute salpingitis. ( 8498424 )
1993
15
Group A streptococcal sepsis secondary to acute salpingitis. ( 8452959 )
1993
16
Persistence of antichlamydial antibodies after treatment of acute salpingitis with doxycycline. ( 8491330 )
1993
17
Epidemiology and hospital course of patients with acute salpingitis and coincident HIV. ( 18475324 )
1993
18
Microbial etiology of urban emergency department acute salpingitis: treatment with ofloxacin. ( 1530018 )
1992
19
Comparison of cefotetan plus doxycycline with cefoxitin plus doxycycline in the inpatient treatment of acute salpingitis. ( 1862460 )
1991
20
Diagnosis and laparoscopic grading of acute salpingitis. ( 1827704 )
1991
21
A randomized trial of ofloxacin versus cefoxitin and doxycycline in the outpatient treatment of acute salpingitis. ( 2031520 )
1991
22
Acute salpingitis--laparoscopic and microbiological evaluation. ( 2139517 )
1990
23
Peritoneal fluid leukotriene B4 and prostaglandin E2 in acute salpingitis. ( 2163350 )
1990
24
Endometrial histopathology in patients with culture-proved upper genital tract infection and laparoscopically diagnosed acute salpingitis. ( 2137304 )
1990
25
Treatment of acute salpingitis with sulbactam/ampicillin. ( 2529873 )
1989
26
Second look laparoscopy; evaluation of two different antibiotic regimens after treatment of acute salpingitis. ( 2523827 )
1989
27
High hepatitis B carrier rate among non-Oriental patients with acute salpingitis. ( 2801832 )
1989
28
Second look laparoscopy after treatment of acute salpingitis with doxycycline/benzylpenicillin procaine or trimethoprim-sulfamethoxazole. ( 2971268 )
1988
29
The combination of pregnancy and acute salpingitis in a case of uterus didelphys. ( 3176931 )
1988
30
Mezlocillin versus doxycycline in the treatment of acute salpingitis. ( 3260343 )
1988
31
Decrease in incidence of women treated in hospital for acute salpingitis in Sweden. ( 3346028 )
1988
32
Endometrial damage in acute salpingitis. ( 3112968 )
1987
33
Acute salpingitis in sterilized women. ( 2949171 )
1987
34
Importance of chlamydial antibodies in acute salpingitis in central Africa. ( 3610162 )
1987
35
Clinical and microbiological investigation of women with acute salpingitis and their consorts. ( 3105573 )
1987
36
Acute salpingitis in sterilized women. ( 3627597 )
1987
37
Clinical and microbiological investigation of women with acute salpingitis and their consorts. ( 3828260 )
1987
38
Acute salpingitis. ( 3117262 )
1987
39
Treatment of acute salpingitis with sulbactam/ampicillin. Comparison with cefoxitin. ( 3013571 )
1986
40
Clinical and microbiological investigation of women with acute salpingitis and their consorts. ( 3741814 )
1986
41
Acute salpingitis subsequent to tubal ligation. ( 3945465 )
1986
42
Combination of bacteriostatic and bactericidal antibiotics in the treatment of acute salpingitis. ( 3099219 )
1986
43
Mezlocillin in the treatment of acute salpingitis. ( 3491303 )
1986
44
Infections with Neisseria gonorrhoeae and Chlamydia trachomatis in women with acute salpingitis. ( 3924816 )
1985
45
Importance of Mycoplasma hominis in acute salpingitis assessed by culture and serological tests. ( 4007861 )
1985
46
Laparoscopic findings and contraceptive use in women with signs and symptoms suggestive of acute salpingitis. ( 3160985 )
1985
47
Endometritis and acute salpingitis associated with Chlamydia trachomatis and herpes simplex virus type two. ( 2982116 )
1985
48
Choice of antibiotics and length of therapy in the treatment of acute salpingitis. ( 3925773 )
1985
49
Immunoperoxidase localization of chlamydial antigens in acute salpingitis. ( 3890547 )
1985
50
Acute salpingitis. Diagnostic and therapeutic dilemmas. ( 6542352 )
1984

Variations for Acute Salpingitis

Expression for Acute Salpingitis

Search GEO for disease gene expression data for Acute Salpingitis.

Pathways for Acute Salpingitis

Pathways related to Acute Salpingitis according to GeneCards Suite gene sharing:

(show all 22)
# Super pathways Score Top Affiliating Genes
1
Show member pathways
12.53 BLK TNF TNFRSF1A TNFRSF1B
2
Show member pathways
12.4 BAK1 HRK MCL1 TNF TNFRSF1A TNFRSF1B
3 12.37 BLK TNF TNFRSF1A TNFRSF1B
4
Show member pathways
11.87 BAK1 BLK HRK MCL1 TNF TNFRSF1A
5 11.82 CD68 MME TNF
6 11.82 BAK1 MCL1 TNF TNFRSF1A TNFRSF1B
7
Show member pathways
11.81 TNF TNFRSF1A TNFRSF1B
8 11.8 MCL1 TNF TNFRSF1B
9 11.75 TNF TNFRSF1A TNFRSF1B
10
Show member pathways
11.62 BAK1 MCL1 TNFRSF1A
11
Show member pathways
11.55 TNF TNFRSF1A TNFRSF1B
12 11.52 CD68 CXCL13 TNF
13 11.49 TNF TNFRSF1A TNFRSF1B
14 11.37 TNF TNFRSF1A TNFRSF1B
15
Show member pathways
11.31 TNF TNFRSF1A TNFRSF1B
16 11.27 TNF TNFRSF1A TNFRSF1B
17
Show member pathways
11.11 BAK1 HRK MCL1 TNFRSF1A
18 11.05 TNF TNFRSF1A TNFRSF1B
19 10.96 TNF TNFRSF1A
20 10.96 BAK1 MCL1 TNF TNFRSF1A
22 10.75 CD68 TNF

GO Terms for Acute Salpingitis

Cellular components related to Acute Salpingitis according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 tumor necrosis factor receptor superfamily complex GO:0002947 8.62 TNFRSF1A TNFRSF1B

Biological processes related to Acute Salpingitis according to GeneCards Suite gene sharing:

(show all 18)
# Name GO ID Score Top Affiliating Genes
1 apoptotic process GO:0006915 9.95 BAK1 HRK MCL1 TNFRSF1A TNFRSF1B
2 cytokine-mediated signaling pathway GO:0019221 9.83 MCL1 TNF TNFRSF1A TNFRSF1B
3 neutrophil degranulation GO:0043312 9.83 CD68 CTSA LYZ MME TNFRSF1B
4 defense response to bacterium GO:0042742 9.81 CXCL13 LYZ TNF TNFRSF1A
5 inflammatory response GO:0006954 9.77 CXCL13 LYZ TNF TNFRSF1A TNFRSF1B
6 defense response GO:0006952 9.75 CXCL13 TNF TNFRSF1A
7 protein localization to plasma membrane GO:0072659 9.74 MRAP TNF TNFRSF1A
8 tumor necrosis factor-mediated signaling pathway GO:0033209 9.65 TNF TNFRSF1A TNFRSF1B
9 negative regulation of cardiac muscle hypertrophy GO:0010614 9.56 TNFRSF1A TNFRSF1B
10 positive regulation of membrane protein ectodomain proteolysis GO:0051044 9.54 TNF TNFRSF1B
11 positive regulation of ceramide biosynthetic process GO:2000304 9.49 TNF TNFRSF1A
12 death-inducing signaling complex assembly GO:0071550 9.46 TNF TNFRSF1A
13 regulation of establishment of endothelial barrier GO:1903140 9.4 TNF TNFRSF1A
14 aortic valve development GO:0003176 9.32 TNFRSF1A TNFRSF1B
15 negative regulation of extracellular matrix constituent secretion GO:0003332 9.26 TNFRSF1A TNFRSF1B
16 positive regulation of apoptotic process involved in morphogenesis GO:1902339 9.16 TNFRSF1A TNFRSF1B
17 intrinsic apoptotic signaling pathway in response to DNA damage GO:0008630 9.02 BAK1 MCL1 TNF TNFRSF1A TNFRSF1B
18 pulmonary valve development GO:0003177 8.96 TNFRSF1A TNFRSF1B

Molecular functions related to Acute Salpingitis according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 tumor necrosis factor-activated receptor activity GO:0005031 8.96 TNFRSF1A TNFRSF1B
2 tumor necrosis factor binding GO:0043120 8.62 TNFRSF1A TNFRSF1B

Sources for Acute Salpingitis

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
17 ExPASy
19 FMA
28 GO
29 GTR
30 HGMD
31 HMDB
32 HPO
33 ICD10
34 ICD10 via Orphanet
35 ICD9CM
36 IUPHAR
37 KEGG
38 LifeMap
40 LOVD
42 MedGen
44 MeSH
45 MESH via Orphanet
46 MGI
49 NCI
50 NCIt
51 NDF-RT
54 NINDS
55 Novoseek
57 OMIM
58 OMIM via Orphanet
62 PubMed
64 QIAGEN
69 SNOMED-CT via HPO
70 SNOMED-CT via Orphanet
71 TGDB
72 Tocris
73 UMLS
74 UMLS via Orphanet
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