MCID: ACT084
MIFTS: 53

Acute Stress Disorder

Categories: Mental diseases
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Aliases & Classifications for Acute Stress Disorder

MalaCards integrated aliases for Acute Stress Disorder:

Name: Acute Stress Disorder 11 14 75
Stress Disorders, Traumatic, Acute 71
Stress Disorders, Traumatic 71
Traumatic Stress Disorder 11

Classifications:



External Ids:

Disease Ontology 11 DOID:6088
ICD9CM 34 308.3
SNOMED-CT 68 192043003
UMLS 71 C0029488 C0038441 C0236816

Summaries for Acute Stress Disorder

Disease Ontology: 11 An anxiety disorder that has symptom flashbacks, has symptom bad dreams, has symptom frightening thoughts, has symptom avoidance or has symptom hyperarousal of PTSD occurring within one month of a traumatic experience as Acute Stress Disorder or ASD.

MalaCards based summary: Acute Stress Disorder, also known as stress disorders, traumatic, acute, is related to multiple personality disorder and sleep apnea, and has symptoms including flashbacks, bad dreams and frightening thoughts. An important gene associated with Acute Stress Disorder is INO80C (INO80 Complex Subunit C), and among its related pathways/superpathways are Signal Transduction and Class A/1 (Rhodopsin-like receptors). The drugs Diazepam and Citalopram have been mentioned in the context of this disorder. Affiliated tissues include brain, prefrontal cortex and amygdala, and related phenotypes are nervous system and homeostasis/metabolism

Wikipedia: 75 Acute stress disorder (ASD, also known as acute stress reaction, psychological shock, mental shock, or... more...

Related Diseases for Acute Stress Disorder

Diseases related to Acute Stress Disorder via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50) (show all 467)
# Related Disease Score Top Affiliating Genes
1 multiple personality disorder 30.9 OXT OGN
2 sleep apnea 30.7 SLC6A4 HTR2A BDNF
3 apnea, obstructive sleep 30.7 POMC HTR2A BDNF
4 psychotic disorder 30.5 SLC6A4 OXT HTR2A GAD2 CRH BDNF
5 headache 30.5 SLC6A4 HTR2A BDNF
6 dissociative amnesia 30.5 OGN FKBP5 CRH BDNF
7 cocaine dependence 30.5 SLC6A4 POMC CRH
8 sleep disorder 30.5 SLC6A4 POMC HTR2A CRH BDNF
9 bulimia nervosa 30.4 SLC6A4 OXT HTR2A BDNF
10 acquired immunodeficiency syndrome 30.3 POMC NR3C1 CRH
11 drug dependence 30.3 SLC6A4 POMC CRH BDNF
12 somatization disorder 30.3 SLC6A4 POMC OXT GAD2 CRH
13 pain agnosia 30.2 POMC OXT CRH BDNF
14 pituitary adenoma 30.2 POMC NR3C1 CRH
15 heroin dependence 30.2 SLC6A4 HTR2A BDNF
16 separation anxiety disorder 30.2 SLC6A4 OXT CRH BDNF
17 amnestic disorder 30.2 OXT OGN BDNF
18 premature ovarian failure 7 30.1 POMC CRH
19 leptin deficiency or dysfunction 30.1 POMC OXT CRH BDNF
20 chronic fatigue syndrome 30.1 SLC6A4 POMC NR3C1 CRH BDNF
21 disease of mental health 30.1 SLC6A4 POMC OXT HTR2A CRHR1 CRH
22 anterograde amnesia 30.1 GAD2 BDNF
23 premature ejaculation 30.1 SLC6A4 OXT BDNF
24 gilles de la tourette syndrome 30.1 SLC6A4 HTR2A BDNF
25 tobacco addiction 30.1 SLC6A4 HTR2A CRHR1 CRH BDNF
26 brunner syndrome 30.1 SLC6A4 HTR2A
27 cannabis abuse 30.1 SLC6A4 BDNF
28 neurotic disorder 30.1 SLC6A4 POMC OXT HTR2A CRH BDNF
29 fibromyalgia 30.1 SLC6A4 POMC OXT HTR2A CRH BDNF
30 retrograde amnesia 30.1 SLC6A4 POMC CRH BDNF
31 paine syndrome 30.0 SLC6A4 POMC CRH BDNF
32 bipolar i disorder 30.0 SLC6A4 HTR2A BDNF
33 paranoid schizophrenia 30.0 SLC6A4 HTR2A BDNF
34 personality disorder 30.0 SLC6A4 NR3C1 HTR2A FKBP5 CRHR2 CRHR1
35 bruxism 30.0 SLC6A4 HTR2A BDNF
36 schizoaffective disorder 30.0 SLC6A4 HTR2A BDNF
37 asperger syndrome 30.0 SLC6A4 OXT BDNF
38 diabetes insipidus 29.9 POMC OXT CRH
39 dissociative disorder 29.9 SLC6A4 OXT OGN HTR2A FKBP5 BDNF
40 amenorrhea 29.9 POMC OXT CRH
41 adult syndrome 29.9 POMC NR3C1 CRH
42 opiate dependence 29.8 SLC6A4 POMC CRHR1 CRH BDNF
43 conduct disorder 29.8 SLC6A4 POMC OXT
44 impulse control disorder 29.8 SLC6A4 HTR2A BDNF
45 intermittent explosive disorder 29.8 SLC6A4 OXT HTR2A
46 borderline personality disorder 29.8 SLC6A4 NR3C1 HTR2A FKBP5 CRHR2 CRHR1
47 serotonin syndrome 29.8 SLC6A4 OXT HTR2A
48 alexithymia 29.8 SLC6A4 PIR OXT HTR2A CRH BDNF
49 migraine with or without aura 1 29.8 SLC6A4 POMC OXT HTR2A CRHR1 CRH
50 narcissistic personality disorder 29.8 PIR OXT

Comorbidity relations with Acute Stress Disorder via Phenotypic Disease Network (PDN):


Anxiety Hypertension, Essential
Intermediate Coronary Syndrome

Graphical network of the top 20 diseases related to Acute Stress Disorder:



Diseases related to Acute Stress Disorder

Symptoms & Phenotypes for Acute Stress Disorder

Symptoms:

11
  • flashbacks
  • bad dreams
  • frightening thoughts
  • avoidance
  • hyperarousal of ptsd occurring

UMLS symptoms related to Acute Stress Disorder:


agitation; motor restlessness; acute stress/transient/situational disturbance

GenomeRNAi Phenotypes related to Acute Stress Disorder according to GeneCards Suite gene sharing:

25
# Description GenomeRNAi Source Accession Score Top Affiliating Genes
1 no effect GR00402-S-1 10.11 BDNF CRH CRHR1 CRHR2 FAM163A FKBP5
2 no effect GR00402-S-2 10.11 BDNF CRH CRHR1 CRHR2 FAM163A FKBP5

MGI Mouse Phenotypes related to Acute Stress Disorder:

45
# Description MGI Source Accession Score Top Affiliating Genes
1 nervous system MP:0003631 10.11 BDNF CRH CRHR1 FKBP5 GAD2 INO80C
2 homeostasis/metabolism MP:0005376 10.07 BDNF CRH CRHR1 CRHR2 FAM163A FKBP5
3 growth/size/body region MP:0005378 9.93 BDNF CRH FAM163A FKBP5 GAD2 INO80C
4 no phenotypic analysis MP:0003012 9.88 BDNF CRH CRHR1 GAD2 NR3C1 POMC
5 adipose tissue MP:0005375 9.8 CRH CRHR2 FAM163A NR3C1 OXT POMC
6 endocrine/exocrine gland MP:0005379 9.7 BDNF CRH CRHR1 CRHR2 GAD2 HTR2A
7 behavior/neurological MP:0005386 9.44 BDNF CRH CRHR1 CRHR2 FKBP5 GAD2

Drugs & Therapeutics for Acute Stress Disorder

Drugs for Acute Stress Disorder (from DrugBank, HMDB, Dgidb, PharmGKB, IUPHAR, NovoSeek, BitterDB):

(show top 50) (show all 271)
# Name Status Phase Clinical Trials Cas Number PubChem Id
1
Diazepam Approved, Illicit, Investigational, Vet_approved Phase 4 439-14-5 3016
2
Citalopram Approved Phase 4 59729-32-7, 59729-33-8 2771
3
Ondansetron Approved, Withdrawn Phase 4 99614-02-5 4595
4
Hydromorphone Approved, Illicit Phase 4 466-99-9, 71-68-1 5284570
5
Cycloserine Approved Phase 4 68-41-7 6234
6
Paroxetine Approved, Investigational Phase 4 61869-08-7 43815
7
Atomoxetine Approved Phase 4 82248-59-7, 83015-26-3 54841
8
Memantine Approved, Investigational Phase 4 41100-52-1, 19982-08-2 4054
9
Mifepristone Approved, Investigational Phase 4 84371-65-3 55245
10
Histamine Approved, Investigational Phase 4 51-45-6 774
11
Mianserin Approved, Investigational Phase 4 24219-97-4 4184
12
Levodopa Approved Phase 4 59-92-7, 63-84-3 6047
13
Vortioxetine Approved, Investigational Phase 4 508233-74-7 9966051
14
Naltrexone Approved, Investigational, Vet_approved Phase 4 16590-41-3 5360515
15
Eszopiclone Approved, Investigational Phase 4 138729-47-2 969472
16
Clonazepam Approved, Illicit Phase 4 1622-61-3 2802
17
Oxytocin Approved, Vet_approved Phase 4 50-56-6 439302 53477758
18
Risperidone Approved, Investigational Phase 4 106266-06-2 5073
19
Prednisone Approved, Vet_approved Phase 4 53-03-2 5865
20
Mirtazapine Approved Phase 4 85650-52-8, 61337-67-5 4205
21
Asenapine Approved Phase 4 85650-56-2, 65576-45-6 163091
22
Tramadol Approved, Investigational Phase 4 27203-92-5 33741 5523
23
Haloperidol Approved Phase 4 52-86-8 3559
24
Carbon monoxide Approved, Investigational Phase 4 630-08-0 281
25
Bupropion Approved Phase 4 31677-93-7, 34841-39-9, 34911-55-2 444
26
Bupivacaine Approved, Investigational Phase 4 2180-92-9, 38396-39-3 2474
27
Diphenhydramine Approved, Investigational Phase 4 147-24-0, 58-73-1 3100
28
Suvorexant Approved, Investigational Phase 4 1030377-33-3 57505028 24965990
29
Promethazine Approved, Investigational Phase 4 60-87-7 4927
30
Pimavanserin Approved, Investigational Phase 4 706779-91-1 10071196
31
Eltanolone Approved, Investigational Phase 4 516-54-1, 128-20-1 31402 92786
32
Propranolol Approved, Investigational Phase 4 318-98-9, 525-66-6 62882 4946
33
Sertraline Approved Phase 4 79617-96-2 68617
34
Prazosin Approved Phase 4 19216-56-9 4893
35
Duloxetine Approved Phase 4 136434-34-9, 116539-59-4 60835
36
Valproic acid Approved, Investigational Phase 4 99-66-1 3121
37
Dexetimide Withdrawn Phase 4 21888-98-2 30843
38 Olive Phase 4
39 Analgesics, Opioid Phase 4
40 Narcotics Phase 4
41 Pharmaceutical Solutions Phase 4
42 Antiemetics Phase 4
43 Gastrointestinal Agents Phase 4
44 Anti-Bacterial Agents Phase 4
45 Anti-Infective Agents Phase 4
46 Antimetabolites Phase 4
47 Antitubercular Agents Phase 4
48 Antibiotics, Antitubercular Phase 4
49
Quetiapine Fumarate Phase 4 111974-72-2
50 Contraceptives, Postcoital Phase 4

Interventional clinical trials:

(show top 50) (show all 1243)
# Name Status NCT ID Phase Drugs
1 Predictors of Treatment Response to Fluoxetine in PTSD Following a Recent History of War Zone Stress Exposure Unknown status NCT00633685 Phase 4 Fluoxetine;Placebo
2 A Prospective Double Blind Randomized Placebo Controlled Trial of Repetitive Transcranial Magnetic Stimulation for Posttraumatic Stress Disorder Unknown status NCT00134446 Phase 4
3 Double Blind, Placebo-Controlled Trial of THC as add-on Therapy for PTSD Unknown status NCT00965809 Phase 4 Tetrahydrocannabinol
4 The Effect of 21-Days Intranasal Oxytocin on Clinical Symptoms and Social Function in Patients With Post Traumatic Stress Disorder (PTSD), a Randomized Controled Trail Unknown status NCT02336568 Phase 4 Oxytoine;PLACEBO
5 Early Pharmacological Intervention With Diazepam in the Emergency Room Setting to Prevent Posttraumatic Stress Disorder (PTSD). Unknown status NCT01221883 Phase 4 Diazepam
6 A Randomized Cross Over Trial of Two Treatments for Obstructive Sleep Apnea in Veterans With Post Traumatic Stress Disorder Unknown status NCT01535586 Phase 4
7 Efficacy of an SSRI in Acute Stress Disorder and PTSD Completed NCT00050804 Phase 4 sertraline
8 Evaluation of the Effects of Low Flow Anesthesia on Pain and Agitation in Patients After Recovery Completed NCT03862391 Phase 4 Analgesics;Antiemetics
9 The Effect of Different Dose of Dexmedetomidine Combined With Hydromorphone in Children With Tonsillectomy and Adenoidectomy Completed NCT03760809 Phase 4 Dexmedetomidine 0.5μg/kg;Dexmedetomidine 1μg/kg
10 Effects of Hydrocortisone and D-Cycloserine on Fear Extinction in Veterans With Posttraumatic Stress Disorder Completed NCT00674570 Phase 4 Hydrocortisone;D-Cycloserine;Placebo
11 Atomoxetine in Comorbid ADHD/PTSD: A Pilot, Placebo-Controlled Feasibility Study Completed NCT02287038 Phase 4 Atomoxetine 80 MG
12 An Open-Label Trial of Memantine for Cognitive Impairment in Patients With Post-Traumatic Stress Disorder Completed NCT02258828 Phase 4 Memantine;Placebo
13 Effects of Paxil CR on Neural Circuits in PTSD Completed NCT00672776 Phase 4 paroxetine;placebo
14 A Pilot Study to Assess the Effects of Doxazosin on Polysomnography in PTSD Completed NCT01959022 Phase 4 Doxazosin XL
15 Pilot Feasibility Study of Pimavanserin for Insomnia in Veterans With Posttraumatic Stress Disorder Completed NCT04188392 Phase 4 Pimavanserin
16 Treatment of Sleep Disturbances in Trauma-affected Refugees: A Randomised Controlled Trial Completed NCT02761161 Phase 4 Mianserin
17 A Psychophysiologic Study of Weakening Traumatic Combat Memories With Post-Reactivation Propranolol Completed NCT00709735 Phase 4 Propranolol;Placebo
18 Neurofunctional Markers of SSRI Treatment Response in PTSD Completed NCT00700999 Phase 4 Paroxetine
19 Evaluation of the Efficacy of Vortioxetine for Posttraumatic Stress Disorder Completed NCT02637895 Phase 4 Placebo;Vortioxetine
20 Dopamine Enhancement of Fear Extinction Learning in PTSD (1R21MH108753) Completed NCT02560389 Phase 4 Placebo;Levodopa
21 Randomized Clinical Trial to Study the Topiramate Efficacy for Posttraumatic Disorder Treatment Completed NCT00725920 Phase 4 Topiramate;placebo control group
22 Retrospective Review of Ketamine Assisted Psychotherapy Program on Mental Health at Field Trip Health Centres in North America Completed NCT05604794 Phase 4
23 Eszopiclone for Sleep Disturbance and Nightmares in Post-Traumatic Stress Disorder Completed NCT00120250 Phase 4 Eszopiclone
24 Combined Treatment With a Benzodiazepine (Clonazepam) and a Selective Serotonin Reuptake Inhibitor (Paroxetine) for Rapid Treatment of Posttraumatic Stress Disorder (PTSD) Completed NCT00025740 Phase 4 clonazepam and paroxetine
25 Prophylaxis of Posttraumatic Stress Disorder With Post-Trauma Propranolol Completed NCT00158262 Phase 4 Propranolol;Placebo
26 Secondary Prevention With Paroxetine vs. Placebo in Subthreshold Posttraumatic Stress Disorder (PTSD) Completed NCT00560612 Phase 4 Paroxetine;Placebo
27 A Study of Sertraline to Prevent PTSD Completed NCT00182078 Phase 4 Placebo;Sertraline
28 Treatment for Psychogenic Nonepileptic Seizures: A Pilot, 12 Week, Prospective, Randomized, Placebo-controlled, Double-blind, Clinical Trial of Sertraline in the Treatment of Comorbid Psychiatric Disorders in NES Completed NCT00159965 Phase 4 sertraline;placebo
29 Prazosin Treatment for Combat Trauma PTSD Nightmares and Sleep Disturbance Completed NCT00108420 Phase 4 Prazosin
30 Naltrexone and Cognitive-Behavioral Therapy for Patients With Alcoholism and Post-Traumatic Stress Disorder Completed NCT00006489 Phase 4 Naltrexone;Placebo
31 Topiramate Treatment of Alcohol Use Disorders in Veterans With Post Traumatic Stress Disorder (PTSD): A Pilot Controlled Trial of Augmentation Therapy Completed NCT01087736 Phase 4 Topiramate
32 Eszopiclone for the Treatment of PTSD Completed NCT01605253 Phase 4 Eszopiclone;Placebo
33 A Placebo-controlled, Randomized, Double-blind Comparison of Placebo vs Short Course Low Dose Corticosteroids on Posttraumatic Stress Disorder (PTSD) Completed NCT00204737 Phase 4 prednisone;placebo
34 Geodon (Ziprasidone) for Posttraumatic Stress Disorder Completed NCT00208208 Phase 4 Ziprasidone
35 Topiramate in the Treatment of Post Traumatic Stress Disorder (PTSD) Completed NCT00203463 Phase 4 topiramate
36 12 Week Prospective Double Blind Placebo Controlled Randomized Trial of Seroquel SR for Alcohol Dependence and Comorbid Anxiety Completed NCT00352469 Phase 4 Seroquel XR
37 Coordinated Anxiety Learning and Management (CALM): Improving Primary Care Anxiety Outcomes Completed NCT00347269 Phase 4 Psychotropic medication optimization
38 A Placebo-controlled Trial of Adjunctive Quetiapine for Refractory PTSD Completed NCT00292370 Phase 4 Open Label (OL) Paroxetine;Placebo;Quetiapine
39 A Randomized, Double-Blind, Placebo-Controlled, Parallel Group Study to Determine the Efficacy and Safety of Topiramate in the Treatment of Posttraumatic Stress Disorder in Civilians Completed NCT00208130 Phase 4 Topiramate
40 Risperidone Monotherapy in the Treatment of PTSD in Women Survivors of Domestic Abuse and Rape Trauma: a Double-Blind, Placebo Controlled, Randomized Clinical Trial Completed NCT00208182 Phase 4 Risperidone
41 Psychophysiology of Delayed Extinction and Reconsolidation in Humans Completed NCT01631682 Phase 4 Propranolol;Mifepristone;Intranasal oxytocin
42 The Outcome of Treatment of Traumatised Refugees With Trauma-Focused Cognitive Behavioural Therapy and / or Antidepressants - a Randomised Controlled Trial Completed NCT00917397 Phase 4 Sertraline
43 Combination Treatment for PTSD After the WTC Attack Completed NCT01130103 Phase 4 Paroxetine
44 Developing Memory Reconsolidation Blockers as Novel PTSD Treatments Completed NCT01490697 Phase 4 Mifepristone;d-Cycloserine;Placebo-matching Mifepristone;Placebo-matching d-Cycloserine (DCS)
45 Effects of Escitalopram on Autonomic Reactivity in Post Traumatic Stress Disorder Among Veterans of Operation Enduring Freedom and Iraqi Freedom (OEF/OIF) Completed NCT01271244 Phase 4 Escitalopram
46 Can Blocking the Orexin System Enhance Sleep's Benefits to Therapeutic Exposure for PTSD? Completed NCT02849548 Phase 4 suvorexant
47 The Treatment of Traumatised Refugees With Sertraline Versus Venlafaxine in Combination With Psychotherapy - a Randomised Clinical Study Completed NCT01569685 Phase 4 Venlafaxine;Sertraline
48 Combined Mirtazapine and Selective Serotonin Reuptake Inhibitor (SSRI) Treatment of Post-traumatic Stress Disorder (PTSD) Completed NCT01178671 Phase 4 Mirtazapine;Sertraline
49 The Effect of Intranasal Oxytocin on Emphatic Abilities in Patients With PTSD Completed NCT01325168 Phase 4 syntocinon nasal spray;placebo nasal spray
50 Reducing Suicidal Ideation Through Treatment of Nightmares-PTSD Completed NCT02199652 Phase 4 Prazosin;Placebo

Search NIH Clinical Center for Acute Stress Disorder

Genetic Tests for Acute Stress Disorder

Anatomical Context for Acute Stress Disorder

Organs/tissues related to Acute Stress Disorder:

MalaCards : Brain, Prefrontal Cortex, Amygdala, Eye, Spinal Cord, Cortex, Temporal Lobe

Publications for Acute Stress Disorder

Articles related to Acute Stress Disorder:

(show top 50) (show all 15022)
# Title Authors PMID Year
1
Neuronal nitric oxide synthase inhibition accelerated the removal of fluoxetine's anxiogenic activity in an animal model of PTSD. 62
36174841 2023
2
Mental health indicators in Sweden over a 12-month period during the COVID-19 pandemic - Baseline data of the Omtanke2020 Study. 62
36379324 2023
3
Internet-delivered psychological treatment as an add-on to treatment as usual for common mental disorders: A systematic review with meta-analysis of randomized trials. 62
36400149 2023
4
Negative emotion-conditioned prepulse induces the attentional enhancement of prepulse inhibition in humans. 62
36330905 2023
5
Work Harassment and Resource Loss Among (Ex)partner Stalking Victims. 62
35549528 2023
6
Melancholic features and typical neurovegetative symptoms of major depressive disorder show specific polygenic patterns. 62
36216191 2023
7
Transcranial Magnetic Stimulation and its Imaging Features in Patients With Depression, Post-traumatic Stress Disorder, and Traumatic Brain Injury. 62
35437218 2023
8
The Safety and Efficacy of Psychedelic-Assisted Therapies for Older Adults: Knowns and Unknowns. 62
36184377 2023
9
Hyper-Sensitivity to the Perpetrator and the Likelihood of Returning to Abusive Relationships. 62
35499214 2023
10
Psychological consequences and daily life adjustment for victims of intimate partner violence. 62
35393871 2023
11
Stress resilience-associated behaviors following predator scent stress are accompanied by upregulated nucleus accumbens mGlu5 transcription in female Sprague Dawley rats. 62
36057378 2023
12
Child Maltreatment and Psychiatric Disorders Increase Risk for Stalking Victimization. 62
35236175 2023
13
Trajectories of Depression, Post-Traumatic Stress, and Chronic Pain Among Women Who Have Separated From an Abusive Partner: A Longitudinal Analysis. 62
35512192 2023
14
Prevalence of common mental health disorders in forcibly displaced populations versus labor migrants by migration phase: A meta-analysis. 62
36367496 2023
15
Post-traumatic Stress Disorder. 62
36402502 2023
16
Longitudinal impact of the COVID19 pandemic on mental health in a general population sample in France: Evidence from the COMET Study. 62
36191642 2023
17
Beyond Viral Suppression-The Impact of Cumulative Violence on Health-Related Quality of Life Among a Cohort of Virally Suppressed Patients. 62
36099083 2023
18
Gut microbiota alterations promote traumatic stress susceptibility associated with p-cresol-induced dopaminergic dysfunctions. 62
36400332 2023
19
Fear extinction induced by activation of PKA ameliorates anxiety-like behavior in PTSD mice. 62
36341808 2023
20
Actigraphic sleep monitoring in patients with post-traumatic stress disorder (PTSD): A meta-analysis. 62
36174789 2023
21
Imagery re-scripting for PTSD: session content and its relation to symptom improvement. 62
36258276 2023
22
Burnout and post-traumatic stress disorder symptoms among medical staff two years after the COVID-19 pandemic in Wuhan, China: Social support and resilience as mediators. 62
36280200 2023
23
Mode of birth and development of maternal postnatal post-traumatic stress disorder: A mixed-methods systematic review and meta-analysis. 62
35561055 2022
24
The brain at rest: Exploratory Neurophysiological Findings Among Men With Histories of Childhood Sexual Abuse. 62
36439659 2022
25
Psychiatric Outcomes of Childhood Maltreatment: A Retrospective Chart Review from a Children's Psychiatric Inpatient Program. 62
34156637 2022
26
Treatment efficacy of tDCS and predictors of treatment response in patients with post-traumatic stress disorder. 62
36055537 2022
27
Sleep Latency and Post-Traumatic Stress Disorder Among Retired Career Florida Firefighters: Evidence From the Advancing Epidemiology of Retired Firefighters Aging Longitudinally Cohort. 62
36221257 2022
28
Comparing Trauma Treatment Outcomes Between Homeless and Housed Veterans in a VA PTSD Clinical Program. 62
36459286 2022
29
MDMA administration attenuates hippocampal IL-β immunoreactivity and subsequent stress-enhanced fear learning: An animal model of PTSD. 62
36388136 2022
30
Factors influencing participation in psychosocial programming among orthopaedic trauma patients with PTSD. 62
36184361 2022
31
Prevalence and sociocultural correlates of post-traumatic stress disorder and complex PTSD among Chinese community health service users in Hong Kong. 62
36457219 2022
32
Activation of ventral tegmental area dopaminergic neurons ameliorates anxiety-like behaviors in single prolonged stress-induced PTSD model rats. 62
36228742 2022
33
Sex differences in the effect of subjective sleep on fear conditioning, extinction learning, and extinction recall in individuals with a range of PTSD symptom severity. 62
36327524 2022
34
Posttraumatic stress disorder, cardiovascular disease outcomes and the modifying role of socioeconomic status. 62
36174781 2022
35
Cardiovascular events in insomnia patients with post-traumatic stress disorder. 62
35994935 2022
36
"When I am breathless now, I don't have the fear that's linked to it": a case series on the potential of EMDR to break the dyspnea-anxiety cycle in COPD. 62
36451139 2022
37
Corticotropin releasing factor in the nucleus basalis of Meynert impairs attentional performance and reduces levels of glutamate and taurine in male and female rats. 62
36216029 2022
38
Thoughts of suicide or self-harm among Australian healthcare workers during the COVID-19 pandemic. 62
35128948 2022
39
Effects of low doses of different nitric oxide (NO) donors in rat models of obsessive-compulsive disorder (OCD) and posttraumatic stress disorder (PTSD). 62
36084795 2022
40
Stress and the brain transcriptome: Identifying commonalities and clusters in standardized data from published experiments. 62
35405299 2022
41
Can Women Shelters Help Reduce Symptoms of PTSD and C-PTSD? Trajectories of PTSD Symptom Development Following Partner- and Family-Related Violence. 62
34986313 2022
42
Depression, anxiety, and post-traumatic stress disorder symptoms after hyperemesis gravidarum: a prospective cohort study. 62
35726837 2022
43
Posttraumatic stress disorder strengthens the momentary associations between emotion dysregulation and substance use: a micro-longitudinal study of community women experiencing intimate partner violence. 62
35792057 2022
44
Landslide disasters in eastern Uganda: post-traumatic stress disorder and its correlates among survivors in Bududa district. 62
36471406 2022
45
[A longitudinal study about post-traumatic stress disorder after delivery in Tunisian primiparous]. 62
34801230 2022
46
Psychosocial aspects of coping that predict post-traumatic stress disorder for African American survivors of homicide victims. 62
36162488 2022
47
The association of mindfulness and psychological well-being among individuals who have recovered from COVID-19 in Jianghan District, Wuhan, China: A cross-sectional study. 62
36162667 2022
48
Post-pandemic stress of COVID-19 among high-risk groups: A systematic review and meta-analysis. 62
36174783 2022
49
Evidence for the beneficial effect of ketamine in the treatment of patients with post-traumatic stress disorder: A systematic review and meta-analysis. 62
35891578 2022
50
Screening tools for post-intensive care syndrome and post-traumatic symptoms in intensive care unit survivors: A scoping review. 62
36464526 2022

Variations for Acute Stress Disorder

Expression for Acute Stress Disorder

Search GEO for disease gene expression data for Acute Stress Disorder.

Pathways for Acute Stress Disorder

Pathways related to Acute Stress Disorder according to GeneCards Suite gene sharing:

(show all 13)
# Super pathways Score Top Affiliating Genes
1 13.47 BDNF CRH CRHR1 CRHR2 FKBP5 HTR2A
2
Show member pathways
13.1 POMC OXT HTR2A CRHR2 CRHR1 CRH
3
Show member pathways
12.35 POMC CRHR2 CRHR1 CRH BDNF
4
Show member pathways
12.11 GAD2 FKBP5 CRH BDNF
5
Show member pathways
11.83 POMC CRHR2 CRHR1 CRH
6 11.76 SLC6A4 NR3C1 HTR2A BDNF
7 11.54 POMC NR3C1 FKBP5
8 11.42 POMC CRHR2 CRHR1 CRH
9 11.39 POMC OXT BDNF
10 10.97 SLC6A4 HTR2A
11 10.87 CRHR2 CRHR1
12
Show member pathways
10.72 POMC HTR2A CRHR1 CRH
13 9.77 POMC CRHR2 CRHR1 CRH

GO Terms for Acute Stress Disorder

Biological processes related to Acute Stress Disorder according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 signal transduction GO:0007165 10.21 BDNF CRH CRHR1 CRHR2 HTR2A NR3C1
2 female pregnancy GO:0007565 9.95 OXT CRHR1 CRH
3 maternal behavior GO:0042711 9.76 OXT NR3C1
4 sleep GO:0030431 9.73 OXT HTR2A
5 parturition GO:0007567 9.71 CRHR1 CRH
6 adrenal gland development GO:0030325 9.63 NR3C1 CRHR1 CRH
7 sperm ejaculation GO:0042713 9.62 SLC6A4 OXT
8 cellular response to corticotropin-releasing hormone stimulus GO:0071376 9.56 CRHR2 CRHR1
9 regulation of corticosterone secretion GO:2000852 9.26 POMC CRHR1
10 memory GO:0007613 9.23 SLC6A4 OXT HTR2A BDNF

Molecular functions related to Acute Stress Disorder according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 serotonin binding GO:0051378 9.46 SLC6A4 HTR2A
2 corticotropin-releasing hormone receptor activity GO:0043404 9.26 CRHR2 CRHR1
3 corticotrophin-releasing factor receptor activity GO:0015056 8.92 CRHR2 CRHR1

Sources for Acute Stress Disorder

2 CDC
6 CNVD
8 Cosmic
9 dbSNP
10 DGIdb
16 EFO
17 ExPASy
18 FMA
19 GARD
27 GO
28 GTR
29 HMDB
30 HPO
31 ICD10
32 ICD10 via Orphanet
33 ICD11
34 ICD9CM
35 IUPHAR
36 LifeMap
38 LOVD
40 MedGen
43 MeSH
44 MESH via Orphanet
45 MGI
48 NCI
49 NCIt
50 NDF-RT
52 NINDS
53 Novoseek
55 ODiseA
56 OMIM via Orphanet
57 OMIM® (Updated 08-Dec-2022)
61 PubChem
62 PubMed
64 QIAGEN
69 SNOMED-CT via HPO
70 Tocris
71 UMLS
72 UMLS via Orphanet
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