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MCID: ACT084
MIFTS: 36

Acute Stress Disorder

Categories: Mental diseases
Genes Tissues Related diseases Publications Symptoms & Phenotypes Drugs
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Aliases & Classifications for Acute Stress Disorder

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MalaCards integrated aliases for Acute Stress Disorder:

Name: Acute Stress Disorder 12 15
Stress Disorders, Traumatic, Acute 73
Stress Disorders, Traumatic 73
Traumatic Stress Disorder 12

Classifications:

MalaCards categories:
Anatomical: Mental diseases
See all MalaCards categories (disease lists)


External Ids:

Disease Ontology 12 DOID:6088
ICD9CM 35 308.3
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Summaries for Acute Stress Disorder

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Disease Ontology : 12 An anxiety disorder that has symptom flashbacks, has symptom bad dreams, has symptom frightening thoughts, has symptom avoidance or has symptom hyperarousal of PTSD occurring within one month of a traumatic experience as Acute Stress Disorder or ASD.

MalaCards based summary : Acute Stress Disorder, also known as stress disorders, traumatic, acute, is related to combat disorder and anxiety, and has symptoms including flashbacks, bad dreams and frightening thoughts. An important gene associated with Acute Stress Disorder is CFDP1 (Craniofacial Development Protein 1). The drugs Sertraline and Neurotransmitter Agents have been mentioned in the context of this disorder. Affiliated tissues include brain, eye and liver.

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Related Diseases for Acute Stress Disorder

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Diseases related to Acute Stress Disorder via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50) (show all 124)
# Related Disease Score Top Affiliating Genes
1 combat disorder 30.6 ACKR1 DIS3 MST1 TRAF3IP2
2 anxiety 11.5
3 multiple personality disorder 11.4
4 post-traumatic stress disorder 10.3
5 major depressive disorder 10.3
6 pain - chronic 10.2
7 schizophrenia 10.2
8 aging 10.2
9 sleep apnea 10.2
10 borderline personality disorder 10.2
11 personality disorder 10.2
12 alcohol dependence 10.1
13 alexithymia 10.1
14 myocardial infarction 10.1
15 dementia 10.1
16 brain injury 10.0
17 traumatic brain injury 10.0
18 attention deficit-hyperactivity disorder 10.0
19 obsessive-compulsive disorder 10.0
20 mental depression 10.0
21 panic disorder 10.0
22 fibromyalgia 10.0
23 depression 10.0
24 breast cancer 10.0
25 autism 10.0
26 asthma 10.0
27 dissociative disorder 10.0
28 psychotic disorder 10.0
29 substance abuse 10.0
30 adjustment disorder 10.0
31 irritable bowel syndrome 10.0
32 heroin dependence 10.0
33 acute myocardial infarction 9.9
34 alzheimer disease 9.9
35 multiple sclerosis 9.9
36 ovarian cancer 9.9
37 alacrima, achalasia, and mental retardation syndrome 9.9
38 alcohol abuse 9.9
39 bipolar disorder 9.9
40 spinal cord injury 9.9
41 sexual disorder 9.9
42 heart disease 9.9
43 somatization disorder 9.9
44 generalized anxiety disorder 9.9
45 disease of mental health 9.9
46 epilepsy 9.9
47 mood disorder 9.9
48 neurotic disorder 9.9
49 infertility 9.9
50 cocaine dependence 9.9

Comorbidity relations with Acute Stress Disorder via Phenotypic Disease Network (PDN):


Anxiety Hypertension, Essential
Intermediate Coronary Syndrome Ischemic Heart Disease

Graphical network of the top 20 diseases related to Acute Stress Disorder:



Diseases related to Acute Stress Disorder
Sources

Symptoms & Phenotypes for Acute Stress Disorder

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Symptoms:

12
  • • flashbacks
  • • bad dreams
  • • frightening thoughts
  • • avoidance or has_symptom hyperarousal of ptsd occurring

UMLS symptoms related to Acute Stress Disorder:


agitation, motor restlessness, acute stress/transient/situational disturbance
Sources

Drugs & Therapeutics for Acute Stress Disorder

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Drugs for Acute Stress Disorder (from DrugBank, HMDB, Dgidb, PharmGKB, IUPHAR, NovoSeek, BitterDB):

(show top 50) (show all 54)
# Name Status Phase Clinical Trials Cas Number PubChem Id
1
Sertraline Approved Phase 4 79617-96-2 68617
2 Neurotransmitter Agents Phase 4,Phase 3,Phase 2,Not Applicable
3 Neurotransmitter Uptake Inhibitors Phase 4,Phase 3
4 Antidepressive Agents Phase 4,Phase 3
5 Serotonin Agents Phase 4,Phase 3
6 Psychotropic Drugs Phase 4,Phase 3,Not Applicable
7 Serotonin Uptake Inhibitors Phase 4,Phase 3
8 Central Nervous System Depressants Phase 4,Not Applicable
9 Anesthetics Phase 4,Not Applicable
10 Peripheral Nervous System Agents Phase 4,Phase 3,Not Applicable
11 Anesthetics, Intravenous Phase 4,Not Applicable
12 Anesthetics, General Phase 4,Not Applicable
13 Analgesics Phase 4,Not Applicable
14
Serotonin Investigational, Nutraceutical Phase 4,Phase 3 50-67-9 5202
15
Citalopram Approved Phase 3 59729-33-8 2771
16 Antiparkinson Agents Phase 3
17 Parasympatholytics Phase 3
18 Cholinergic Antagonists Phase 3
19 Antidepressive Agents, Second-Generation Phase 3
20 Cholinergic Agents Phase 3
21 Muscarinic Antagonists Phase 3
22 Autonomic Agents Phase 3
23
Carvedilol Approved, Investigational Phase 2 72956-09-3 2585
24
Propranolol Approved, Investigational Phase 2 525-66-6 4946
25
Prazosin Approved Phase 2 19216-56-9 4893
26 Vasodilator Agents Phase 2
27 Adrenergic alpha-1 Receptor Antagonists Phase 2
28 Adrenergic alpha-Antagonists Phase 2
29 Adrenergic beta-Antagonists Phase 2
30 Adrenergic Antagonists Phase 2
31 Antihypertensive Agents Phase 2
32 Adrenergic Agents Phase 2,Not Applicable
33 Anti-Arrhythmia Agents Phase 2
34 Hydroxymethylglutaryl-CoA Reductase Inhibitors Phase 2
35 Atorvastatin Calcium Phase 2 134523-03-8
36 Calcium, Dietary Phase 2
37 Hypolipidemic Agents Phase 2
38 Anticholesteremic Agents Phase 2
39 Antimetabolites Phase 2
40 Lipid Regulating Agents Phase 2
41 Protective Agents Phase 2
42 Neuroprotective Agents Phase 2
43
Dexmedetomidine Approved, Vet_approved Not Applicable 113775-47-6 68602 5311068
44
Midazolam Approved, Illicit Not Applicable 59467-70-8 4192
45 Analgesics, Non-Narcotic Not Applicable
46 Adrenergic alpha-Agonists Not Applicable
47 GABA Agents Not Applicable
48 Adjuvants, Anesthesia Not Applicable
49 GABA Modulators Not Applicable
50 Tranquilizing Agents Not Applicable

Interventional clinical trials:

(show all 41)
# Name Status NCT ID Phase Drugs
1 Evaluation of Stress Disorders Completed NCT00050804 Phase 4 sertraline
2 Dexmedetomidine Combined With Hydromorphone in Tonsillectomy and Adenoidectomy Not yet recruiting NCT03760809 Phase 4 Dexmedetomidine 0.5μg／kg;Dexmedetomidine 1μg／kg
3 PTSD Prevention Study Examining the Efficacy of Sertraline in Burn Victims Terminated NCT02520726 Phase 4 Sertraline;Placebo oral capsule
4 A Randomized, Double-Blind Study of Placebo vs. Ketamine For Use During Dressing Changes in Critically Ill Burn Patients Withdrawn NCT02336308 Phase 4 Ketamine;Placebo, Normal Saline
5 Study Testing if Fast or Slow rTMS is Better for the Treatment of Posttraumatic Stress Disorder (PTSD) Active, not recruiting NCT02158663 Phase 2, Phase 3
6 SSRI Administration to Reduce Acute Stress Disorder Symptoms and Prevent Depression and PTSD in Physical Trauma Victims Terminated NCT00114374 Phase 3 Escitalopram
7 Carvedilol Versus Placebo for Treatment in Post Traumatic Stress Disorder (PTSD) Unknown status NCT01221792 Phase 2 Carvedilol;Placebo
8 Propranolol for the Treatment of Acute Stress Disorder Completed NCT00069355 Phase 2 Propranolol
9 Explorative Open Label Study of Efficacy Profile of Neurexan® in Experimental Acute Stress Setting in Healthy Subjects Completed NCT01703832 Phase 1, Phase 2 Neurexan®
10 Explorative Efficacy Profile of Neurexan® in an Experimental Acute Stress Setting in Healthy Subjects Completed NCT01703819 Phase 1, Phase 2 Neurexan®
11 Neuronal Correlates of Neurexan® Action in Mildly to Moderately Stressed Probands Completed NCT02602275 Phase 2 Neurexan®
12 Efficacy of Prazosin in Preventing Post-traumatic Stress Disorder Recruiting NCT03045016 Phase 2 Prazosin, ALPRESS® LP 2,5 et 5 mg
13 Posttraumatic Stress Disorders in Police, Correctional Service Officers, and 911 Operators Recruiting NCT03152175 Phase 2 Propranolol Hydrochloride;Placebo
14 Mission Connect Mild Traumatic Brain Injury (TBI) Integrated Clinical Protocol Terminated NCT01013870 Phase 2 Atorvastatin;Placebo
15 Virtual Reality for Burn Wound Care Pain Control Unknown status NCT00663013 Not Applicable
16 Early Prevention of PTSD in Patients Within One Week of Acute Physical Trauma Unknown status NCT02915497 Not Applicable
17 Behavioral Treatments for Acute Stress Disorder In Firefighters Completed NCT00183508 Not Applicable
18 Psychological Interventions in Children After Road Traffic Accidents or Burns Completed NCT01085370 Not Applicable
19 Prevention of Intrusive Memories and Posttraumatic Stress Symptoms After Emergency Cesarean Section Completed NCT02502513 Not Applicable
20 Family Communication and Support in the Pediatric Intensive Care Unit Completed NCT02144779 Not Applicable
21 Intervention to Decrease Anxiety in Parents of Infants in the Neonatal Intensive Care Unit (NICU) Completed NCT00186472 Not Applicable
22 Prevention of Post-traumatic Stress Disorder by Telephone Based Cognitive Behavioral Therapy Completed NCT00889005 Not Applicable
23 Preventing Long Term Psychiatric Disability Among Those With Major Burn Injuries Completed NCT00988104 Not Applicable
24 Effect of Nature Based Sounds' Intervention on Agitation and Anxiety of Patients Admitted in Intensive Care Units. Completed NCT03213782 Not Applicable
25 Emotion And Symptom-focused Engagement (EASE): An Intervention for Individuals With Acute Leukemia Completed NCT02353559 Not Applicable
26 Early Detection of Patients at Risk of Developing a Post-traumatic Stress Disorder After a Stay in Intensive Care Unit Completed NCT03278171
27 Improving Psychological Distress Among Critical Illness Survivors and Their Caregivers Completed NCT01983254 Not Applicable
28 Dexmedetomidine Versus Midazolam for Facilitating Extubation Completed NCT00744380 Not Applicable Midazolam;Dexmedetomidine
29 Intervention to Reduce Stress in 0-5 Year Olds With Burns Completed NCT00844896 Not Applicable
30 Plasticity of the Compassionate Brain Completed NCT01833104 Not Applicable
31 Early Prevention of Post Traumatic Stress Disorder Completed NCT02004743 Not Applicable
32 Swiss TrAumatic biRth Trial Recruiting NCT03576586 Not Applicable
33 Prevention of Post Traumatic Stress Disorder Following Trauma by Attention Control Training Recruiting NCT02591485 Not Applicable
34 Pilot Trial of Inpatient Cognitive Therapy for the Prevention of Suicide in Military Personnel Active, not recruiting NCT01356186 Not Applicable
35 Probabilistic Risk Modeling for Disorder Post Traumatic Stress (PTSD) After the Attacks in Paris In November 2015 Enrolling by invitation NCT02853513
36 GASA-CIR Trail (Guidance and the Symptoms of Acute Stress and Anxiety in Critically Ill Patients Relatives in Intensive Care Unit) Not yet recruiting NCT03812458 Not Applicable
37 Predictive Factors of PTSD in Adults Admitted to an Emergency Service Not yet recruiting NCT03615014 Not Applicable
38 Online Psychoeducation for the Prevention of PTSD Not yet recruiting NCT03496714 Not Applicable
39 Cognitive-behavioral Therapy for Treatment of Post-traumatic Stress Disorder and Related Problems Not yet recruiting NCT03019497 Not Applicable
40 Anxiety Reduction Treatment for Acute Trauma Terminated NCT02315378 Not Applicable
41 Hair Cortisol Level as a Predictor of PTSD Development Withdrawn NCT01804426

Search NIH Clinical Center for Acute Stress Disorder

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Genetic Tests for Acute Stress Disorder

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Anatomical Context for Acute Stress Disorder

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MalaCards organs/tissues related to Acute Stress Disorder:

41
Brain, Eye, Liver, Heart, Breast, Spinal Cord, Placenta
Sources

Publications for Acute Stress Disorder

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Articles related to Acute Stress Disorder:

(show top 50) (show all 193)
# Title Authors Year
1
Acute stress disorder and C-reactive protein in patients with acute myocardial infarction. ( 29488809 )
2018
2
Prevalence of acute stress disorder among road traffic accident survivors: a meta-analysis. ( 29895273 )
2018
3
Acute stress disorder and C-reactive protein in patients with acute myocardial infarction. ( 29243511 )
2018
4
Treatment of acute stress disorder for victims of violent crime. ( 30089232 )
2018
5
Prevalence of post-traumatic stress disorder, acute stress disorder and depression following violence related injury treated at the emergency department: a systematic review. ( 30253782 )
2018
6
The Current Evidence for Acute Stress Disorder. ( 30315408 )
2018
7
Impaired Executive Functioning of Sexual Assault Survivors with Acute Stress Disorder. ( 30332748 )
2018
8
Acute stress disorder and defense mechanisms: a study of physical trauma patients admitted to an emergency hospital. ( 29211115 )
2017
9
Acute stress disorder and the transition to posttraumatic stress disorder in children and adolescents: Prevalence, course, prognosis, diagnostic suitability, and risk markers. ( 28135019 )
2017
10
Acute stress disorder. ( 28813311 )
2017
11
Acute stress disorder symptoms after evaluation for acute coronary syndrome predict 30-day readmission. ( 28377184 )
2017
12
Exploring DSM-5 criterion A in Acute Stress Disorder symptoms following natural disaster. ( 28709061 )
2017
13
Gender Differences in the Prediction of Acute Stress Disorder From Peritraumatic Dissociation and Distress Among Victims of Violent Crimes. ( 29294663 )
2017
14
Trauma memory characteristics and the development of acute stress disorder and post-traumatic stress disorder in youth. ( 27467024 )
2016
15
The latent structure of Acute Stress Disorder symptoms in trauma-exposed children and adolescents. ( 27472990 )
2016
16
Acute stress disorder as a predictor of posttraumatic stress: A longitudinal study of Chinese children exposed to the Lushan earthquake. ( 27329012 )
2016
17
Predicting the Transition From Acute Stress Disorder to Posttraumatic Stress Disorder in Children With Severe Injuries. ( 26776839 )
2016
18
Beyond Bounds of Reality: Acute Stress Disorder Presenting with Delusional Misidentification Syndromes. ( 28163527 )
2016
19
Trauma-Related Context Increases Sleep Disturbances in People with Acute Stress Disorder Symptoms. ( 27062710 )
2016
20
Posterior and prefrontal contributions to the development posttraumatic stress disorder symptom severity: an fMRI study of symptom provocation in acute stress disorder. ( 27455992 )
2016
21
Perception of a hectic hospital environment at admission relates to acute stress disorder symptoms in myocardial infarction patients. ( 26725540 )
2016
22
Cognitive Load Undermines Thought Suppression in Acute Stress Disorder. ( 27157032 )
2016
23
Acute stress disorder among civilians during a war and post-traumatic growth six years later: the impact of personal and social resources. ( 26000657 )
2015
24
Association between Media Use, Acute Stress Disorder and Psychological Distress. ( 26022976 )
2015
25
Pharmacological prevention of post-traumatic stress disorder and acute stress disorder: a systematic review and meta-analysis. ( 26360285 )
2015
26
Examining the Latent Structure of Acute Stress Disorder Symptoms in Filipino-Victims of a Flashflood Disaster. ( 25575912 )
2015
27
Does acute stress disorder predict subsequent posttraumatic stress disorder in pediatric burn survivors? ( 26581092 )
2015
28
Acute stress disorder modifies cerebral activity of amygdala and prefrontal cortex. ( 25599382 )
2015
29
Acute Stress Disorder Symptoms Predict All-Cause Mortality Among Myocardial Infarction Patients: a 15-Year Longitudinal Study. ( 26507907 )
2015
30
Assessing DSM-5 latent subtypes of acute stress disorder dissociative or intrusive? ( 25535010 )
2015
31
Utilizing Telehealth to Support Treatment of Acute Stress Disorder in a Theater of War: Prolonged Exposure via Clinical Videoconferencing. ( 25764266 )
2015
32
Corrections. Pharmacological prevention of post-traumatic stress disorder and acute stress disorder: a systematic review and meta-analysis. ( 26303542 )
2015
33
Resilience as a correlate of acute stress disorder symptoms in patients with acute myocardial infarction. ( 26568834 )
2015
34
A comparison of the capacity of DSM-IV and DSM-5 acute stress disorder definitions to predict posttraumatic stress disorder and related disorders. ( 25562379 )
2014
35
How to help women at risk for acute stress disorder after childbirth. ( 25495965 )
2014
36
Posterior Midline Activation during Symptom Provocation in Acute Stress Disorder: An fMRI Study. ( 24847285 )
2014
37
Different Profiles of Acute Stress Disorder Differentially Predict Posttraumatic Stress Disorder in a Large Sample of Female Victims of Sexual Trauma. ( 24978131 )
2014
38
Thought control strategies and rumination in youth with acute stress disorder and posttraumatic stress disorder following single-event trauma. ( 24521228 )
2014
39
Possible Risk Factors for Acute Stress Disorder and Post-Traumatic Stress Disorder After an Industrial Explosion. ( 28360591 )
2014
40
Predictors of acute stress disorder severity. ( 23466400 )
2013
41
The latent factor structure of acute stress disorder following bank robbery: testing alternative models in light of the pending DSM-5. ( 23398114 )
2013
42
Associative memory impairment in acute stress disorder: characteristics and time course. ( 23312478 )
2013
43
Persistent fear of aftershocks, impairment of working memory, and acute stress disorder predict post-traumatic stress disorder: 6-month follow-up of help seekers following the L'Aquila earthquake. ( 24324929 )
2013
44
Response inhibition and cognitive appraisal in clients with acute stress disorder and posttraumatic stress disorder. ( 24454421 )
2013
45
Does acute stress disorder predict posttraumatic stress disorder following bank robbery? ( 22829214 )
2013
46
Acute stress disorder versus chronic posttraumatic stress disorder: inhibition of fear as a function of time since trauma. ( 22907890 )
2013
47
The physician's role in managing acute stress disorder. ( 23062092 )
2012
48
Symptoms of acute stress disorder in mothers of premature infants. ( 22864005 )
2012
49
The capacity of acute stress disorder to predict posttraumatic psychiatric disorders. ( 22088925 )
2012
50
The structure of acute stress disorder among Chinese adults exposed to an earthquake: is dysphoric arousal a unique construct of acute posttraumatic responses? ( 22882702 )
2012
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Variations for Acute Stress Disorder

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Expression for Acute Stress Disorder

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Search GEO for disease gene expression data for Acute Stress Disorder.
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Pathways for Acute Stress Disorder

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GO Terms for Acute Stress Disorder

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Sources for Acute Stress Disorder

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3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
17 ExPASy
19 FMA
28 GO
29 GTR
30 HGMD
31 HMDB
32 HPO
33 ICD10
34 ICD10 via Orphanet
35 ICD9CM
36 IUPHAR
37 KEGG
38 LifeMap
40 LOVD
42 MedGen
44 MeSH
45 MESH via Orphanet
46 MGI
49 NCI
50 NCIt
51 NDF-RT
54 NINDS
55 Novoseek
57 OMIM
58 OMIM via Orphanet
62 PubMed
64 QIAGEN
69 SNOMED-CT via HPO
70 SNOMED-CT via Orphanet
71 TGDB
72 Tocris
73 UMLS
74 UMLS via Orphanet
The MalaCards human disease database index: 1-9 A B C D E F G H I J K L M N O P Q R S T U V W X Y Z
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