Home
User Guide
What's in a MalaCard Search Guide Our Sources
Analysis Tools
GeneCards GeneAnalytics GeneAlaCart PathCards VarElect TGex
News and Views Disease Lists/Categories
About
About MalaCards Our Publications Academic Licensing Weizmann Institute LifeMap Discovery® Terms of Use MalaCards Team
MCID: ACT084
MIFTS: 34

Acute Stress Disorder

Categories: Mental diseases
Genes Tissues Related diseases Publications Symptoms & Phenotypes Drugs
Sources

Aliases & Classifications for Acute Stress Disorder

About this section

MalaCards integrated aliases for Acute Stress Disorder:

Name: Acute Stress Disorder 12 15
Stress Disorders, Traumatic, Acute 73
Stress Disorders, Traumatic 73
Traumatic Stress Disorder 12

Classifications:

MalaCards categories:
Anatomical: Mental diseases
See all MalaCards categories (disease lists)


External Ids:

Disease Ontology 12 DOID:6088
ICD9CM 35 308.3
SNOMED-CT 68 192040000 192043003
Sources

Summaries for Acute Stress Disorder

About this section
Disease Ontology : 12 An anxiety disorder that has symptom flashbacks, has symptom bad dreams, has symptom frightening thoughts, has symptom avoidance or has symptom hyperarousal of PTSD occurring within one month of a traumatic experience as Acute Stress Disorder or ASD.

MalaCards based summary : Acute Stress Disorder, also known as stress disorders, traumatic, acute, is related to combat disorder and post-traumatic stress disorder, and has symptoms including flashbacks, bad dreams and frightening thoughts. An important gene associated with Acute Stress Disorder is CFDP1 (Craniofacial Development Protein 1). The drugs Sertraline and Neurotransmitter Agents have been mentioned in the context of this disorder. Affiliated tissues include brain, testes and amygdala.

Sources

Related Diseases for Acute Stress Disorder

About this section

Diseases related to Acute Stress Disorder via text searches within MalaCards or GeneCards Suite gene sharing:

(show all 11)
# Related Disease Score Top Affiliating Genes
1 combat disorder 28.6 ACKR1 DIS3 MST1 TRAF3IP2
2 post-traumatic stress disorder 10.1
3 burns 10.0
4 myocardial infarction 10.0
5 brain injury 9.9
6 traumatic brain injury 9.9
7 depression 9.9
8 acute myocardial infarction 9.8
9 aging 9.7
10 ischemia 9.5
11 cerebritis 9.5

Comorbidity relations with Acute Stress Disorder via Phenotypic Disease Network (PDN):


Anxiety Hypertension, Essential
Intermediate Coronary Syndrome Ischemic Heart Disease

Graphical network of the top 20 diseases related to Acute Stress Disorder:



Diseases related to Acute Stress Disorder
Sources

Symptoms & Phenotypes for Acute Stress Disorder

About this section

Symptoms:

12
  • • flashbacks
  • • bad dreams
  • • frightening thoughts
  • • avoidance or has_symptom hyperarousal of ptsd occurring

UMLS symptoms related to Acute Stress Disorder:


agitation, acute stress/transient/situational disturbance, motor restlessness
Sources

Drugs & Therapeutics for Acute Stress Disorder

About this section

Drugs for Acute Stress Disorder (from DrugBank, HMDB, Dgidb, PharmGKB, IUPHAR, NovoSeek, BitterDB):

(show top 50) (show all 55)
# Name Status Phase Clinical Trials Cas Number PubChem Id
1
Sertraline Approved Phase 4 79617-96-2 68617
2 Neurotransmitter Agents Phase 4,Phase 3,Phase 2,Not Applicable
3 Analgesics Phase 4,Not Applicable
4 Central Nervous System Depressants Phase 4,Not Applicable
5 Serotonin Agents Phase 4,Phase 3
6 Serotonin Uptake Inhibitors Phase 4,Phase 3
7 Neurotransmitter Uptake Inhibitors Phase 4,Phase 3
8 Anesthetics Phase 4,Not Applicable
9 Anesthetics, General Phase 4,Not Applicable
10 Anesthetics, Intravenous Phase 4,Not Applicable
11 Peripheral Nervous System Agents Phase 4,Phase 3,Not Applicable
12 Antidepressive Agents Phase 4,Phase 3
13 Psychotropic Drugs Phase 4,Phase 3,Not Applicable
14
Serotonin Investigational, Nutraceutical Phase 4,Phase 3 50-67-9 5202
15
Citalopram Approved Phase 3 59729-33-8 2771
16 Cholinergic Agents Phase 3
17 Muscarinic Antagonists Phase 3
18 Cholinergic Antagonists Phase 3
19 Parasympatholytics Phase 3
20 Antidepressive Agents, Second-Generation Phase 3
21 Antiparkinson Agents Phase 3
22 Autonomic Agents Phase 3
23
Carvedilol Approved, Investigational Phase 2 72956-09-3 2585
24
Propranolol Approved, Investigational Phase 2 525-66-6 4946
25
Prazosin Approved Phase 2 19216-56-9 4893
26 Adrenergic Agents Phase 2,Not Applicable
27 Adrenergic alpha-1 Receptor Antagonists Phase 2
28 Adrenergic alpha-Antagonists Phase 2
29 Adrenergic Antagonists Phase 2
30 Adrenergic beta-Antagonists Phase 2
31 Vasodilator Agents Phase 2
32 Antihypertensive Agents Phase 2
33 Anti-Arrhythmia Agents Phase 2
34 Atorvastatin Calcium Phase 2 134523-03-8
35 Neuroprotective Agents Phase 2
36 Hydroxymethylglutaryl-CoA Reductase Inhibitors Phase 2
37 Hypolipidemic Agents Phase 2
38 Anticholesteremic Agents Phase 2
39 Protective Agents Phase 2
40 Lipid Regulating Agents Phase 2
41 Antimetabolites Phase 2
42 Calcium, Dietary Phase 2
43
Midazolam Approved, Illicit Not Applicable 59467-70-8 4192
44
Dexmedetomidine Approved, Vet_approved Not Applicable 113775-47-6 68602 5311068
45
Menthol Approved Not Applicable 2216-51-5 16666
46 Adjuvants, Anesthesia Not Applicable
47 Adrenergic Agonists Not Applicable
48 Adrenergic alpha-2 Receptor Agonists Not Applicable
49 Adrenergic alpha-Agonists Not Applicable
50 GABA Agents Not Applicable

Interventional clinical trials:

(show all 38)
# Name Status NCT ID Phase Drugs
1 Evaluation of Stress Disorders Completed NCT00050804 Phase 4 sertraline
2 PTSD Prevention Study Examining the Efficacy of Sertraline in Burn Victims Terminated NCT02520726 Phase 4 Sertraline;Placebo oral capsule
3 A Randomized, Double-Blind Study of Placebo vs. Ketamine For Use During Dressing Changes in Critically Ill Burn Patients Withdrawn NCT02336308 Phase 4 Ketamine;Placebo, Normal Saline
4 Study Testing if Fast or Slow rTMS is Better for the Treatment of Posttraumatic Stress Disorder (PTSD) Active, not recruiting NCT02158663 Phase 2, Phase 3
5 SSRI Administration to Reduce Acute Stress Disorder Symptoms and Prevent Depression and PTSD in Physical Trauma Victims Terminated NCT00114374 Phase 3 Escitalopram
6 Carvedilol Versus Placebo for Treatment in Post Traumatic Stress Disorder (PTSD) Unknown status NCT01221792 Phase 2 Carvedilol;Placebo
7 Propranolol for the Treatment of Acute Stress Disorder Completed NCT00069355 Phase 2 Propranolol
8 Explorative Open Label Study of Efficacy Profile of Neurexan® in Experimental Acute Stress Setting in Healthy Subjects Completed NCT01703832 Phase 1, Phase 2 Neurexan®
9 Explorative Efficacy Profile of Neurexan® in an Experimental Acute Stress Setting in Healthy Subjects Completed NCT01703819 Phase 1, Phase 2 Neurexan®
10 Neuronal Correlates of Neurexan® Action in Mildly to Moderately Stressed Probands Completed NCT02602275 Phase 2 Neurexan®
11 Efficacy of Prazosin in Preventing Post-traumatic Stress Disorder Recruiting NCT03045016 Phase 2 Prazosin, ALPRESS® LP 2,5 et 5 mg
12 Posttraumatic Stress Disorders in Police, Correctional Service Officers, and 911 Operators Recruiting NCT03152175 Phase 2 Propranolol Hydrochloride;Placebo
13 Mission Connect Mild Traumatic Brain Injury (TBI) Integrated Clinical Protocol Terminated NCT01013870 Phase 2 Atorvastatin;Placebo
14 Virtual Reality for Burn Wound Care Pain Control Unknown status NCT00663013 Not Applicable
15 Behavioral Treatments for Acute Stress Disorder In Firefighters Completed NCT00183508 Not Applicable
16 Psychological Interventions in Children After Road Traffic Accidents or Burns Completed NCT01085370 Not Applicable
17 Prevention of Intrusive Memories and Posttraumatic Stress Symptoms After Emergency Cesarean Section Completed NCT02502513 Not Applicable
18 Family Communication and Support in the Pediatric Intensive Care Unit Completed NCT02144779 Not Applicable
19 Intervention to Decrease Anxiety in Parents of Infants in the Neonatal Intensive Care Unit (NICU) Completed NCT00186472 Not Applicable
20 Prevention of Post-traumatic Stress Disorder by Telephone Based Cognitive Behavioral Therapy Completed NCT00889005 Not Applicable
21 Effect of Nature Based Sounds' Intervention on Agitation and Anxiety of Patients Admitted in Intensive Care Units. Completed NCT03213782 Not Applicable
22 Emotion And Symptom-focused Engagement (EASE): An Intervention for Individuals With Acute Leukemia Completed NCT02353559 Not Applicable
23 Improving Psychological Distress Among Critical Illness Survivors and Their Caregivers Completed NCT01983254 Not Applicable
24 Dexmedetomidine Versus Midazolam for Facilitating Extubation Completed NCT00744380 Not Applicable Midazolam;Dexmedetomidine
25 Intervention to Reduce Stress in 0-5 Year Olds With Burns Completed NCT00844896 Not Applicable
26 Plasticity of the Compassionate Brain Completed NCT01833104 Not Applicable
27 Early Prevention of Post Traumatic Stress Disorder Completed NCT02004743 Not Applicable
28 Prevention of Post Traumatic Stress Disorder Following Trauma by Attention Control Training Recruiting NCT02591485 Not Applicable
29 Pilot Trial of Inpatient Cognitive Therapy for the Prevention of Suicide in Military Personnel Active, not recruiting NCT01356186 Not Applicable
30 Preventing Long Term Psychiatric Disability Among Those With Major Burn Injuries Active, not recruiting NCT00988104 Not Applicable
31 Probabilistic Risk Modeling for Disorder Post Traumatic Stress (PTSD) After the Attacks in Paris In November 2015 Enrolling by invitation NCT02853513
32 Early Prevention of PTSD in Patients Within One Week of Acute Physical Trauma Enrolling by invitation NCT02915497 Not Applicable
33 Swiss TrAumatic biRth Trial Not yet recruiting NCT03576586 Not Applicable
34 Early Detection of Patients at Risk of Developing a Post-traumatic Stress Disorder After a Stay in Intensive Care Unit Not yet recruiting NCT03278171
35 Online Psychoeducation for the Prevention of PTSD Not yet recruiting NCT03496714 Not Applicable
36 Cognitive-behavioral Therapy for Treatment of Post-traumatic Stress Disorder and Related Problems Not yet recruiting NCT03019497 Not Applicable
37 Anxiety Reduction Treatment for Acute Trauma Terminated NCT02315378 Not Applicable
38 Hair Cortisol Level as a Predictor of PTSD Development Withdrawn NCT01804426

Search NIH Clinical Center for Acute Stress Disorder

Sources

Genetic Tests for Acute Stress Disorder

About this section
Sources

Anatomical Context for Acute Stress Disorder

About this section

MalaCards organs/tissues related to Acute Stress Disorder:

41
Brain, Testes, Amygdala, Prefrontal Cortex, Cortex, Eye
Sources

Publications for Acute Stress Disorder

About this section

Articles related to Acute Stress Disorder:

(show top 50) (show all 187)
# Title Authors Year
1
Acute stress disorder and C-reactive protein in patients with acute myocardial infarction. ( 29488809 )
2018
2
Prevalence of acute stress disorder among road traffic accident survivors: a meta-analysis. ( 29895273 )
2018
3
Acute stress disorder and C-reactive protein in patients with acute myocardial infarction. ( 29243511 )
2018
4
Acute stress disorder and defense mechanisms: a study of physical trauma patients admitted to an emergency hospital. ( 29211115 )
2017
5
Acute stress disorder and the transition to posttraumatic stress disorder in children and adolescents: Prevalence, course, prognosis, diagnostic suitability, and risk markers. ( 28135019 )
2017
6
Acute stress disorder. ( 28813311 )
2017
7
Acute stress disorder symptoms after evaluation for acute coronary syndrome predict 30-day readmission. ( 28377184 )
2017
8
Exploring DSM-5 criterion A in Acute Stress Disorder symptoms following natural disaster. ( 28709061 )
2017
9
Gender Differences in the Prediction of Acute Stress Disorder From Peritraumatic Dissociation and Distress Among Victims of Violent Crimes. ( 29294663 )
2017
10
Trauma memory characteristics and the development of acute stress disorder and post-traumatic stress disorder in youth. ( 27467024 )
2016
11
The latent structure of Acute Stress Disorder symptoms in trauma-exposed children and adolescents. ( 27472990 )
2016
12
Acute stress disorder as a predictor of posttraumatic stress: A longitudinal study of Chinese children exposed to the Lushan earthquake. ( 27329012 )
2016
13
Predicting the Transition From Acute Stress Disorder to Posttraumatic Stress Disorder in Children With Severe Injuries. ( 26776839 )
2016
14
Beyond Bounds of Reality: Acute Stress Disorder Presenting with Delusional Misidentification Syndromes. ( 28163527 )
2016
15
Trauma-Related Context Increases Sleep Disturbances in People with Acute Stress Disorder Symptoms. ( 27062710 )
2016
16
Posterior and prefrontal contributions to the development posttraumatic stress disorder symptom severity: an fMRI study of symptom provocation in acute stress disorder. ( 27455992 )
2016
17
Perception of a hectic hospital environment at admission relates to acute stress disorder symptoms in myocardial infarction patients. ( 26725540 )
2016
18
Cognitive Load Undermines Thought Suppression in Acute Stress Disorder. ( 27157032 )
2016
19
Acute stress disorder among civilians during a war and post-traumatic growth six years later: the impact of personal and social resources. ( 26000657 )
2015
20
Association between Media Use, Acute Stress Disorder and Psychological Distress. ( 26022976 )
2015
21
Pharmacological prevention of post-traumatic stress disorder and acute stress disorder: a systematic review and meta-analysis. ( 26360285 )
2015
22
Examining the Latent Structure of Acute Stress Disorder Symptoms in Filipino-Victims of a Flashflood Disaster. ( 25575912 )
2015
23
Does acute stress disorder predict subsequent posttraumatic stress disorder in pediatric burn survivors? ( 26581092 )
2015
24
Acute stress disorder modifies cerebral activity of amygdala and prefrontal cortex. ( 25599382 )
2015
25
Acute Stress Disorder Symptoms Predict All-Cause Mortality Among Myocardial Infarction Patients: a 15-Year Longitudinal Study. ( 26507907 )
2015
26
Assessing DSM-5 latent subtypes of acute stress disorder dissociative or intrusive? ( 25535010 )
2015
27
Utilizing Telehealth to Support Treatment of Acute Stress Disorder in a Theater of War: Prolonged Exposure via Clinical Videoconferencing. ( 25764266 )
2015
28
Corrections. Pharmacological prevention of post-traumatic stress disorder and acute stress disorder: a systematic review and meta-analysis. ( 26303542 )
2015
29
Resilience as a correlate of acute stress disorder symptoms in patients with acute myocardial infarction. ( 26568834 )
2015
30
A comparison of the capacity of DSM-IV and DSM-5 acute stress disorder definitions to predict posttraumatic stress disorder and related disorders. ( 25562379 )
2014
31
How to help women at risk for acute stress disorder after childbirth. ( 25495965 )
2014
32
Posterior Midline Activation during Symptom Provocation in Acute Stress Disorder: An fMRI Study. ( 24847285 )
2014
33
Different Profiles of Acute Stress Disorder Differentially Predict Posttraumatic Stress Disorder in a Large Sample of Female Victims of Sexual Trauma. ( 24978131 )
2014
34
Thought control strategies and rumination in youth with acute stress disorder and posttraumatic stress disorder following single-event trauma. ( 24521228 )
2014
35
Predictors of acute stress disorder severity. ( 23466400 )
2013
36
The latent factor structure of acute stress disorder following bank robbery: testing alternative models in light of the pending DSM-5. ( 23398114 )
2013
37
Associative memory impairment in acute stress disorder: characteristics and time course. ( 23312478 )
2013
38
Persistent fear of aftershocks, impairment of working memory, and acute stress disorder predict post-traumatic stress disorder: 6-month follow-up of help seekers following the L'Aquila earthquake. ( 24324929 )
2013
39
Response inhibition and cognitive appraisal in clients with acute stress disorder and posttraumatic stress disorder. ( 24454421 )
2013
40
Does acute stress disorder predict posttraumatic stress disorder following bank robbery? ( 22829214 )
2013
41
Acute stress disorder versus chronic posttraumatic stress disorder: inhibition of fear as a function of time since trauma. ( 22907890 )
2013
42
The physician's role in managing acute stress disorder. ( 23062092 )
2012
43
Symptoms of acute stress disorder in mothers of premature infants. ( 22864005 )
2012
44
The capacity of acute stress disorder to predict posttraumatic psychiatric disorders. ( 22088925 )
2012
45
The structure of acute stress disorder among Chinese adults exposed to an earthquake: is dysphoric arousal a unique construct of acute posttraumatic responses? ( 22882702 )
2012
46
Patient Education Page. Coping with acute stress disorder. ( 23062098 )
2012
47
Cognitive processing therapy versus supportive counseling for acute stress disorder following assault: a randomized pilot trial. ( 23046784 )
2012
48
Assessing a dysphoric arousal model of acute stress disorder symptoms in a clinical sample of rape and bank robbery victims. ( 22893845 )
2012
49
Acute stress disorder revisited. ( 21275643 )
2011
50
The nature of trauma memories in acute stress disorder in children and adolescents. ( 21073462 )
2011
Sources

Variations for Acute Stress Disorder

About this section
Sources

Expression for Acute Stress Disorder

About this section
Search GEO for disease gene expression data for Acute Stress Disorder.
Sources

Pathways for Acute Stress Disorder

About this section
Sources

GO Terms for Acute Stress Disorder

About this section
Sources

Sources for Acute Stress Disorder

About this section
3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
17 ExPASy
19 FMA
28 GO
29 GTR
30 HGMD
31 HMDB
32 HPO
33 ICD10
34 ICD10 via Orphanet
35 ICD9CM
36 IUPHAR
37 KEGG
38 LifeMap
40 LOVD
42 MedGen
44 MeSH
45 MESH via Orphanet
46 MGI
49 NCI
50 NCIt
51 NDF-RT
54 NINDS
55 Novoseek
57 OMIM
58 OMIM via Orphanet
62 PubMed
64 QIAGEN
69 SNOMED-CT via HPO
70 SNOMED-CT via Orphanet
71 TGDB
72 Tocris
73 UMLS
74 UMLS via Orphanet
The MalaCards human disease database index: 1-9 A B C D E F G H I J K L M N O P Q R S T U V W X Y Z
Content
Loading form....