Aliases & Classifications for Acute Stress Disorder

MalaCards integrated aliases for Acute Stress Disorder:

Name: Acute Stress Disorder 12 15
Stress Disorders, Traumatic, Acute 70
Stress Disorders, Traumatic 70
Traumatic Stress Disorder 12


External Ids:

Disease Ontology 12 DOID:6088
ICD9CM 34 308.3
SNOMED-CT 67 192043003
UMLS 70 C0029488 C0038441 C0236816

Summaries for Acute Stress Disorder

Disease Ontology : 12 An anxiety disorder that has symptom flashbacks, has symptom bad dreams, has symptom frightening thoughts, has symptom avoidance or has symptom hyperarousal of PTSD occurring within one month of a traumatic experience as Acute Stress Disorder or ASD.

MalaCards based summary : Acute Stress Disorder, also known as stress disorders, traumatic, acute, is related to combat disorder and sleep apnea, and has symptoms including flashbacks, bad dreams and frightening thoughts. An important gene associated with Acute Stress Disorder is CRP (C-Reactive Protein), and among its related pathways/superpathways are cAMP signaling pathway and G alpha (s) signalling events. The drugs Fluoxetine and Tramadol have been mentioned in the context of this disorder. Affiliated tissues include amygdala, eye and cortex, and related phenotypes are behavior/neurological and homeostasis/metabolism

Wikipedia : 73 Acute stress disorder (ASD, also known as acute stress reaction, psychological shock, mental shock, or... more...

Related Diseases for Acute Stress Disorder

Diseases related to Acute Stress Disorder via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50) (show all 419)
# Related Disease Score Top Affiliating Genes
1 combat disorder 31.7 SERPINA3 NENF IL6
2 sleep apnea 30.9 SLC6A4 IL6 CRP BDNF
3 alcohol use disorder 30.9 SLC6A4 HTR1A CRHR1 CRH BDNF
4 post-traumatic stress disorder 30.7 SLC6A4 POMC NR3C1 FKBP5 CRP CRHR1
5 psychotic disorder 30.7 SLC6A4 SERPINA3 OXT HTR1A BDNF
6 cocaine dependence 30.6 SLC6A4 POMC BDNF
7 bulimia nervosa 30.6 SLC6A4 OXT BDNF
8 alexithymia 30.4 SLC6A4 OXT IL6 HTR1A CRP
9 fibromyalgia 30.4 SLC6A4 POMC IL6 CRP CRH BDNF
10 placenta disease 30.4 SERPINA3 OXT IL6 CRP
11 tobacco addiction 30.4 SLC6A4 SERPINA3 CRHR1 CRH BDNF
12 opiate dependence 30.3 SLC6A4 POMC CRH
13 dissociative disorder 30.3 SLC6A4 OXT FKBP5 BDNF
14 sexual disorder 30.3 SLC6A4 POMC OXT HTR1A BDNF
15 eating disorder 30.2 SLC6A4 POMC CRHR2 CRH BDNF
16 bipolar i disorder 30.2 SLC6A4 HTR1A BDNF
17 drug dependence 30.2 SLC6A4 POMC CRHR1 CRH BDNF
18 separation anxiety disorder 30.2 SLC6A4 OXT HTR1A
19 pulmonary disease, chronic obstructive 30.1 SLC6A4 SERPINA3 NR3C1 IL6 CRP
20 sleep disorder 30.1 SLC6A4 POMC IL6 HTR1A CRP CRH
21 schizoaffective disorder 30.1 SLC6A4 HTR1A BDNF
22 agoraphobia 30.1 SLC6A4 HTR1A CRHR1 CRH
23 vascular dementia 30.1 SERPINA3 IL6 HTR1A CRP
24 neurotic disorder 30.1 SLC6A4 POMC OXT IL6 HTR1A BDNF
25 substance dependence 30.1 SLC6A4 SERPINA3 POMC IL6 CRHR1 CRH
26 personality disorder 30.0 SLC6A4 NR3C1 HTR1A FKBP5 CRHR2 CRHR1
27 diabetes insipidus 30.0 POMC OXT CRH
28 retrograde amnesia 30.0 SLC6A4 POMC HTR1A BDNF
29 intermittent explosive disorder 30.0 SLC6A4 OXT HTR1A
30 premature ejaculation 30.0 SLC6A4 OXT HTR1A
31 serotonin syndrome 30.0 SLC6A4 OXT HTR1A
32 autism spectrum disorder 29.9 SLC6A4 POMC OXT NR3C1 FKBP5 BDNF
33 paranoid schizophrenia 29.9 SLC6A4 IL6 HTR1A BDNF
34 constipation 29.9 SLC6A4 IL6 CRP BDNF
35 fragile x syndrome 29.9 SLC6A4 OXT CRHR1 BDNF
36 substance abuse 29.9 SLC6A4 SERPINA3 POMC IL6 HTR1A CRP
37 attention deficit-hyperactivity disorder 29.9 SLC6A4 OXT NR3C1 IL6 HTR1A FKBP5
38 borderline personality disorder 29.9 SLC6A4 NR3C1 HTR1A FKBP5 CRHR2 CRHR1
39 amnestic disorder 29.9 OXT HTR1A BDNF
40 somatization disorder 29.8 SLC6A4 POMC OXT IL6 HTR1A CRH
41 glucose metabolism disease 29.8 SERPINA3 POMC IL6 CRP
42 bipolar disorder 29.8 SLC6A4 NR3C1 IL6 HTR1A FKBP5 CRP
43 acquired immunodeficiency syndrome 29.8 POMC NR3C1 IL6 CRP
44 anorexia nervosa 29.8 SLC6A4 POMC OXT HTR1A CRH BDNF
45 migraine with or without aura 1 29.6 SLC6A4 POMC OXT IL6 HTR1A CRP
46 generalized anxiety disorder 29.6 SLC6A4 NR3C1 HTR1A CRP CRHR1 BDNF
47 asthma 29.6 SLC6A4 SERPINA3 POMC NR3C1 IL6 FKBP5
48 dysthymic disorder 29.6 SLC6A4 POMC IL6 HTR1A CRP CRH
49 depression 29.6 SLC6A4 NR3C1 HTR1A CRHR1 CRH BDNF
50 social phobia 29.5 SLC6A4 SERPINA3 OXT HTR1A CRHR1 CRH

Comorbidity relations with Acute Stress Disorder via Phenotypic Disease Network (PDN):

Anxiety Hypertension, Essential
Intermediate Coronary Syndrome

Graphical network of the top 20 diseases related to Acute Stress Disorder:

Diseases related to Acute Stress Disorder

Symptoms & Phenotypes for Acute Stress Disorder


  • flashbacks
  • bad dreams
  • frightening thoughts
  • avoidance
  • hyperarousal of ptsd occurring

UMLS symptoms related to Acute Stress Disorder:

agitation; motor restlessness; acute stress/transient/situational disturbance

MGI Mouse Phenotypes related to Acute Stress Disorder:

# Description MGI Source Accession Score Top Affiliating Genes
1 behavior/neurological MP:0005386 10.24 BATF2 BDNF CRH CRHR1 CRHR2 FKBP5
2 homeostasis/metabolism MP:0005376 10.13 BDNF CRH CRHR1 CRHR2 CRP FKBP4
3 endocrine/exocrine gland MP:0005379 10.06 BDNF CRH CRHR1 CRHR2 FKBP4 IL6
4 integument MP:0010771 9.81 BDNF CRH FKBP4 IL6 NR3C1 OXT
5 nervous system MP:0003631 9.73 BDNF CRH CRHR1 FKBP5 HTR1A IL6
6 no phenotypic analysis MP:0003012 9.17 BDNF CRH CRHR1 HTR1A LYPD1 NR3C1

Drugs & Therapeutics for Acute Stress Disorder

Drugs for Acute Stress Disorder (from DrugBank, HMDB, Dgidb, PharmGKB, IUPHAR, NovoSeek, BitterDB):

(show top 50) (show all 264)
# Name Status Phase Clinical Trials Cas Number PubChem Id
Fluoxetine Approved, Vet_approved Phase 4 54910-89-3 3386
Tramadol Approved, Investigational Phase 4 27203-92-5 33741
Diazepam Approved, Illicit, Investigational, Vet_approved Phase 4 439-14-5 3016
Ondansetron Approved Phase 4 99614-02-5 4595
Hydromorphone Approved, Illicit Phase 4 466-99-9 5284570
Histamine Approved, Investigational Phase 4 51-45-6, 75614-87-8 774
Mirtazapine Approved Phase 4 85650-52-8, 61337-67-5 4205
Oxytocin Approved, Vet_approved Phase 4 50-56-6 53477758 439302
Memantine Approved, Investigational Phase 4 19982-08-2 4054
Eszopiclone Approved, Investigational Phase 4 138729-47-2 969472
Naltrexone Approved, Investigational, Vet_approved Phase 4 16590-41-3 5360515
Mifepristone Approved, Investigational Phase 4 84371-65-3 55245
Ziprasidone Approved Phase 4 146939-27-7 60854
Risperidone Approved, Investigational Phase 4 106266-06-2 5073
Prednisone Approved, Vet_approved Phase 4 53-03-2 5865
Clonazepam Approved, Illicit Phase 4 1622-61-3 2802
Mianserin Approved, Investigational Phase 4 24219-97-4 4184
Vortioxetine Approved, Investigational Phase 4 508233-74-7 9966051
Levodopa Approved Phase 4 59-92-7 6047
Asenapine Approved Phase 4 85650-56-2, 65576-45-6 3001386
Haloperidol Approved Phase 4 52-86-8 3559
Bupropion Approved Phase 4 34841-39-9, 34911-55-2 444
Carbon monoxide Approved, Investigational Phase 4 630-08-0 281
Promethazine Approved, Investigational Phase 4 60-87-7 4927
Diphenhydramine Approved, Investigational Phase 4 58-73-1, 147-24-0 3100
Suvorexant Approved, Investigational Phase 4 1030377-33-3
Pimavanserin Approved, Investigational Phase 4 706779-91-1 16058810
Sertraline Approved Phase 4 79617-96-2 68617
Propranolol Approved, Investigational Phase 4 525-66-6 4946
Paroxetine Approved, Investigational Phase 4 61869-08-7 43815
Valproic acid Approved, Investigational Phase 4 99-66-1 3121
32 Olive Phase 4
33 Antimetabolites Phase 4
34 Pharmaceutical Solutions Phase 4
35 Serotonin 5-HT3 Receptor Antagonists Phase 4
Histamine Phosphate Phase 4 51-74-1 65513
37 Histamine H1 Antagonists Phase 4
38 Histamine Antagonists Phase 4
39 Serotonin 5-HT1 Receptor Agonists Phase 4
40 Serotonin Receptor Agonists Phase 4
41 Hormones Phase 4
42 Antibiotics, Antitubercular Phase 4
43 Anti-Bacterial Agents Phase 4
44 Antitubercular Agents Phase 4
45 Quetiapine Fumarate Phase 4 111974-72-2
46 Contraceptives, Postcoital Phase 4
47 Hormone Antagonists Phase 4
48 Contraceptives, Oral Phase 4
49 Contraceptive Agents Phase 4
50 Antineoplastic Agents, Hormonal Phase 4

Interventional clinical trials:

(show top 50) (show all 1071)
# Name Status NCT ID Phase Drugs
1 The Effect of 21-Days Intranasal Oxytocin on Clinical Symptoms and Social Function in Patients With Post Traumatic Stress Disorder (PTSD), a Randomized Controled Trail Unknown status NCT02336568 Phase 4 Oxytoine;PLACEBO
2 A Double-Blind, Placebo-Controlled, Flexible-Dose Pilot Clinical Trial of Once-Daily Extended-Release Tramadol for the Treatment of PTSD Unknown status NCT01517711 Phase 4 Tramadol;Placebo
3 A Prospective Double Blind Randomized Placebo Controlled Trial of Repetitive Transcranial Magnetic Stimulation for Posttraumatic Stress Disorder Unknown status NCT00134446 Phase 4
4 A Randomized Cross Over Trial of Two Treatments for Obstructive Sleep Apnea in Veterans With Post Traumatic Stress Disorder Unknown status NCT01535586 Phase 4
5 Early Pharmacological Intervention With Diazepam in the Emergency Room Setting to Prevent Posttraumatic Stress Disorder (PTSD). Unknown status NCT01221883 Phase 4 Diazepam
6 Double Blind, Placebo-Controlled Trial of THC as add-on Therapy for PTSD Unknown status NCT00965809 Phase 4 Tetrahydrocannabinol
7 Predictors of Treatment Response to Fluoxetine in PTSD Following a Recent History of War Zone Stress Exposure Unknown status NCT00633685 Phase 4 Fluoxetine;Placebo
8 Efficacy of an SSRI in Acute Stress Disorder and PTSD Completed NCT00050804 Phase 4 sertraline
9 Evaluation of the Effects of Low Flow Anesthesia on Pain and Agitation in Patients After Recovery Completed NCT03862391 Phase 4 Analgesics;Antiemetics
10 The Effect of Different Dose of Dexmedetomidine Combined With Hydromorphone in Children With Tonsillectomy and Adenoidectomy Completed NCT03760809 Phase 4 Dexmedetomidine 0.5μg/kg;Dexmedetomidine 1μg/kg
11 Cognitive Behavioral Therapy vs. Sertraline in the Treatment of Post Traumatic Stress Disorder Completed NCT00391430 Phase 4 Sertraline
12 Combined Mirtazapine and Selective Serotonin Reuptake Inhibitor (SSRI) Treatment of Post-traumatic Stress Disorder (PTSD) Completed NCT01178671 Phase 4 Mirtazapine;Sertraline
13 An Open-Label Trial of Memantine for Cognitive Impairment in Patients With Post-Traumatic Stress Disorder Completed NCT02258828 Phase 4 Memantine;Placebo
14 Topiramate Treatment of Alcohol Use Disorders in Veterans With Post Traumatic Stress Disorder (PTSD): A Pilot Controlled Trial of Augmentation Therapy Completed NCT01087736 Phase 4 Topiramate
15 Eszopiclone for Sleep Disturbance and Nightmares in Post-Traumatic Stress Disorder Completed NCT00120250 Phase 4 Eszopiclone
16 Naltrexone and Cognitive-Behavioral Therapy for Patients With Alcoholism and Post-Traumatic Stress Disorder Completed NCT00006489 Phase 4 Naltrexone;Placebo
17 Topiramate in the Treatment of Post Traumatic Stress Disorder (PTSD) Completed NCT00203463 Phase 4 topiramate
18 Effects of Escitalopram on Autonomic Reactivity in Post Traumatic Stress Disorder Among Veterans of Operation Enduring Freedom and Iraqi Freedom (OEF/OIF) Completed NCT01271244 Phase 4 Escitalopram
19 Randomized Trial of Sertraline, Prolonged Exposure, and Their Combination for Post-traumatic Stress Disorder (PTSD) in Operation Enduring Freedom/Operation Iraqi Freedom (OEF/OIF). Completed NCT01524133 Phase 4 Sertraline
20 Coordinated Anxiety Learning and Management (CALM): Improving Primary Care Anxiety Outcomes Completed NCT00347269 Phase 4 Psychotropic medication optimization
21 Prophylaxis of Posttraumatic Stress Disorder With Post-Trauma Propranolol Completed NCT00158262 Phase 4 Propranolol;Placebo
22 A Randomized, Double-Blind, Placebo-Controlled, Parallel Group Study to Determine the Efficacy and Safety of Topiramate in the Treatment of Posttraumatic Stress Disorder in Civilians Completed NCT00208130 Phase 4 Topiramate
23 A Placebo-controlled, Randomized, Double-blind Comparison of Placebo vs Short Course Low Dose Corticosteroids on Posttraumatic Stress Disorder (PTSD) Completed NCT00204737 Phase 4 prednisone;placebo
24 Combined Treatment With a Benzodiazepine (Clonazepam) and a Selective Serotonin Reuptake Inhibitor (Paroxetine) for Rapid Treatment of Posttraumatic Stress Disorder (PTSD) Completed NCT00025740 Phase 4 clonazepam and paroxetine
25 Treatment of Sleep Disturbances in Trauma-affected Refugees: A Randomised Controlled Trial Completed NCT02761161 Phase 4 Mianserin
26 Risperidone Monotherapy in the Treatment of PTSD in Women Survivors of Domestic Abuse and Rape Trauma: a Double-Blind, Placebo Controlled, Randomized Clinical Trial Completed NCT00208182 Phase 4 Risperidone
27 Atomoxetine in Comorbid ADHD/PTSD: A Pilot, Placebo-Controlled Feasibility Study Completed NCT02287038 Phase 4 Atomoxetine 80 MG
28 Developing Memory Reconsolidation Blockers as Novel PTSD Treatments Completed NCT01490697 Phase 4 Mifepristone;d-Cycloserine;Placebo-matching Mifepristone;Placebo-matching d-Cycloserine (DCS)
29 The Effect of Intranasal Oxytocin on Emphatic Abilities in Patients With PTSD Completed NCT01325168 Phase 4 syntocinon nasal spray;placebo nasal spray
30 Evaluation of the Efficacy of Vortioxetine for Posttraumatic Stress Disorder Completed NCT02637895 Phase 4 Placebo;Vortioxetine
31 The Outcome of Treatment of Traumatised Refugees With Trauma-Focused Cognitive Behavioural Therapy and / or Antidepressants - a Randomised Controlled Trial Completed NCT00917397 Phase 4 Sertraline
32 Neurofunctional Markers of SSRI Treatment Response in PTSD Completed NCT00700999 Phase 4 Paroxetine
33 The Treatment of Traumatised Refugees With Sertraline Versus Venlafaxine in Combination With Psychotherapy - a Randomised Clinical Study Completed NCT01569685 Phase 4 Venlafaxine;Sertraline
34 Pilot Feasibility Study of Pimavanserin for Insomnia in Veterans With Posttraumatic Stress Disorder Completed NCT04188392 Phase 4 Pimavanserin
35 Reducing Suicidal Ideation Through Treatment of Nightmares-PTSD Completed NCT02199652 Phase 4 Prazosin;Placebo
36 12 Week Prospective Double Blind Placebo Controlled Randomized Trial of Seroquel SR for Alcohol Dependence and Comorbid Anxiety Completed NCT00352469 Phase 4 Seroquel XR
37 Prazosin Treatment for Combat Trauma PTSD Nightmares and Sleep Disturbance Completed NCT00108420 Phase 4 Prazosin
38 Geodon (Ziprasidone) for Posttraumatic Stress Disorder Completed NCT00208208 Phase 4 Ziprasidone
39 A Placebo-controlled Trial of Adjunctive Quetiapine for Refractory PTSD Completed NCT00292370 Phase 4 Open Label (OL) Paroxetine;Placebo;Quetiapine
40 A Study of Sertraline to Prevent PTSD Completed NCT00182078 Phase 4 Placebo;Sertraline
41 Treatment for Psychogenic Nonepileptic Seizures: A Pilot, 12 Week, Prospective, Randomized, Placebo-controlled, Double-blind, Clinical Trial of Sertraline in the Treatment of Comorbid Psychiatric Disorders in NES Completed NCT00159965 Phase 4 sertraline;placebo
42 Combination Treatment for PTSD After the WTC Attack Completed NCT01130103 Phase 4 Paroxetine
43 Secondary Prevention With Paroxetine vs. Placebo in Subthreshold Posttraumatic Stress Disorder (PTSD) Completed NCT00560612 Phase 4 Paroxetine;Placebo
44 Eszopiclone for the Treatment of PTSD Completed NCT01605253 Phase 4 Eszopiclone;Placebo
45 Effects of Paxil CR on Neural Circuits in PTSD Completed NCT00672776 Phase 4 paroxetine;placebo
46 Effects of Hydrocortisone and D-Cycloserine on Fear Extinction in Veterans With Posttraumatic Stress Disorder Completed NCT00674570 Phase 4 Hydrocortisone;D-Cycloserine;Placebo
47 A Pilot Study to Assess the Effects of Doxazosin on Polysomnography in PTSD Completed NCT01959022 Phase 4 Doxazosin XL
48 Randomized Clinical Trial to Study the Topiramate Efficacy for Posttraumatic Disorder Treatment Completed NCT00725920 Phase 4 Topiramate;placebo control group
49 A Psychophysiologic Study of Weakening Traumatic Combat Memories With Post-Reactivation Propranolol Completed NCT00709735 Phase 4 Propranolol;Placebo
50 Dopamine Enhancement of Fear Extinction Learning in PTSD (1R21MH108753) Completed NCT02560389 Phase 4 Placebo;Levodopa

Search NIH Clinical Center for Acute Stress Disorder

Genetic Tests for Acute Stress Disorder

Anatomical Context for Acute Stress Disorder

MalaCards organs/tissues related to Acute Stress Disorder:

Amygdala, Eye, Cortex, Brain, Prefrontal Cortex, Pituitary, Breast

Publications for Acute Stress Disorder

Articles related to Acute Stress Disorder:

(show top 50) (show all 12434)
# Title Authors PMID Year
miR-132 downregulation alleviates behavioral impairment of rats exposed to single prolonged stress, reduces the level of apoptosis in PFC, and upregulates the expression of MeCP2 and BDNF. 61
33718536 2021
Community Violence, PTSD, Hopelessness, Substance Use, and Perpetuation of Violence in an Urban Environment. 61
32737673 2021
Cortical gyrification morphology in PTSD: A neurobiological risk factor for severity? 61
33659579 2021
A novel arousal-based individual screening reveals susceptibility and resilience to PTSD-like phenotypes in mice. 61
33392367 2021
Substance use predictors of attendance among veterans in integrated PTSD and alcohol use disorder treatment. 61
33771279 2021
Ventral Tegmental Area Dysfunction and Disruption of Dopaminergic Homeostasis: Implications for Post-traumatic Stress Disorder. 61
33428093 2021
ICD-11 complex Post Traumatic Stress Disorder (CPTSD) in parents with perinatal bereavement: Implications for treatment and care. 61
33610906 2021
Cerebellar and multi-system metabolic reprogramming associated with trauma exposure and post-traumatic stress disorder (PTSD)-like behavior in mice. 61
33604421 2021
Increased risk of mental health disorders in patients with RA during the COVID-19 pandemic: a possible surge and solutions. 61
33710419 2021
Retrospectively assessed trajectories of PTSD symptoms and their subsequent comorbidities. 61
33578109 2021
Ketamine-50 years in use: from anesthesia to rapid antidepressant effects and neurobiological mechanisms. 61
33609274 2021
To Be or Not to Be Flexible: Selective impairments as a means to differentiate between depression and PTSD symptoms. 61
33639329 2021
Sleep and Interpersonal Violence: A Systematic Review. 61
31131736 2021
Prevalence and Correlates of the Co-Occurrence of Family Violence: A Meta-Analysis on Family Polyvictimization. 61
31068102 2021
Childhood adversity trajectories and PTSD in young adulthood: A nationwide Danish register-based cohort study of more than one million individuals. 61
33621913 2021
Hydroxynorketamines: Pharmacology and Potential Therapeutic Applications. 61
33674359 2021
Long-term mortality and quality of life after trauma: an ancillary study from the prospective multicenter trial FROG-ICU. 61
31214722 2021
Development and treatment of cognitive inflexibility in sub-chronic stress-re-stress (SRS) model of PTSD. 61
33389726 2021
Relations Between Cultural Life Scripts, Individual Life Stories, and Psychological Distress. 61
32208807 2021
Use of Children as Soldiers. 61
33678297 2021
Ginsenoside Rg1 Prevents PTSD-Like Behaviors in Mice Through Promoting Synaptic Proteins, Reducing Kir4.1 and TNF-α in the Hippocampus. 61
33215390 2021
Hydrocortisone administration for reducing post-traumatic stress symptoms: A systematic review and meta-analysis. 61
33626392 2021
The Association Between Patient Health Status and Surrogate Decision Maker PTSD Symptoms in Chronic Critical Illness. 61
33794122 2021
Axonal damage and behavioral deficits in rats with repetitive exposure of the brain to laser-induced shock waves: Effects of inter-exposure time. 61
33592306 2021
[Psychosocial stress, high blood pressure and cardiovascular risk]. 61
33060048 2021
The Psychological Effects of Musculoskeletal Trauma. 61
33475305 2021
Predictors of Depressive Symptoms and Post Traumatic Stress Disorder Among Women Engaged in Commercial Sex Work in Southern Uganda. 61
33636517 2021
A gender comparative analysis of post-traumatic stress disorder among a community-based cohort of people who use drugs in Vancouver, Canada. 61
33421746 2021
Physical Restraints and Post-Traumatic Stress Disorder in Survivors of Critical Illness. A Systematic Review and Meta-analysis. 61
33075240 2021
Successful treatment of post-traumatic stress disorder reverses DNA methylation marks. 61
31645664 2021
Diffusion Tensor Imaging Reveals White Matter Differences in Military Personnel Exposed to Trauma with and without Post-traumatic Stress Disorder. 61
33582526 2021
Post-traumatic stress disorder as a moderator of transdiagnostic, residential eating disorder treatment outcome trajectory. 61
33449390 2021
Post-traumatic stress disorder due to sexual abuse and its relation to pain sensitivity among patients in methadone maintenance treatment. 61
33652250 2021
Post-traumatic Stress Disorder in Middle Age and Beyond. 61
33766192 2021
Development of a pain neuroscience education program for post-traumatic stress disorder and pain. 61
31232667 2021
Improving maternal postpartum mental health screening guidelines requires assessment of post-traumatic stress disorder. 61
32780347 2021
The Comprehensive Communal Trauma Intervention Model (CCTIM), an Innovative Transdisciplinary Population-Level Model for Treating Trauma-Induced Illness and Mental Health in Global Vulnerable Communities: Palestine, a Case Study. 61
33811577 2021
Content Validity of Parental Stressor Scale: Pediatric Intensive Care Unit (PSS:PICU). 61
32795163 2021
The effect of COVID-19 epidemic on the sexual function of healthcare professionals. 61
33438223 2021
Post-traumatic stress disorder symptoms in non-muscle-invasive bladder cancer survivors: A population-based study. 61
33308978 2021
Mental health and psychosocial support in conflict: children's protection concerns and intervention outcomes in Syria. 61
33794955 2021
Combination therapy with neuropeptides for the treatment of anxiety disorder. 61
33607407 2021
The impact on mental health patients of COVID-19 outbreak in Spain. 61
33588226 2021
Prevalence and correlates of post-traumatic stress disorder after ischaemic stroke. 61
31452093 2021
Psychological or educational eHealth interventions on depression, anxiety or stress following preterm birth: a systematic review. 61
32336122 2021
The effect of COVID-19 pandemic on the mental health of Canadian critical care nurses providing patient care during the early phase pandemic: A mixed method study. 61
33342649 2021
The association between witnessing patient death and mental health outcomes in frontline COVID-19 healthcare workers. 61
33544405 2021
College student mental health risks during the COVID-19 pandemic: Implications of campus relocation. 61
33588225 2021
Prospective prediction of PTSD and depressive symptoms during social unrest and COVID-19 using a brief online tool. 61
33545423 2021
A mediating role for mental health in associations between COVID-19-related self-stigma, PTSD, quality of life, and insomnia among patients recovered from COVID-19. 61
33811451 2021

Variations for Acute Stress Disorder

Expression for Acute Stress Disorder

Search GEO for disease gene expression data for Acute Stress Disorder.

Pathways for Acute Stress Disorder

GO Terms for Acute Stress Disorder

Cellular components related to Acute Stress Disorder according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 extracellular space GO:0005615 9.61 SERPINA3 POMC OXT NENF NDNF IL6
2 extracellular region GO:0005576 9.32 SERPINA3 POMC OXT NENF NDNF LYPD1

Biological processes related to Acute Stress Disorder according to GeneCards Suite gene sharing:

(show all 12)
# Name GO ID Score Top Affiliating Genes
1 female pregnancy GO:0007565 9.69 OXT CRHR1 CRH
2 memory GO:0007613 9.67 SLC6A4 OXT BDNF
3 signal transduction GO:0007165 9.65 POMC OXT NR3C1 NENF IL6 HTR1A
4 acute-phase response GO:0006953 9.5 SERPINA3 IL6 CRP
5 negative regulation of lipid storage GO:0010888 9.48 IL6 CRP
6 parturition GO:0007567 9.46 CRHR1 CRH
7 cellular response to corticotropin-releasing hormone stimulus GO:0071376 9.43 CRHR2 CRHR1
8 sperm ejaculation GO:0042713 9.4 SLC6A4 OXT
9 response to ether GO:0045472 9.37 OXT CRH
10 regulation of corticosterone secretion GO:2000852 9.26 POMC CRHR1
11 regulation of serotonin secretion GO:0014062 9.16 HTR1A CRH
12 vasoconstriction GO:0042310 8.8 SLC6A4 HTR1A CRP

Molecular functions related to Acute Stress Disorder according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 protein binding GO:0005515 10.3 SLC6A4 SERPINA3 POMC OXT NR3C1 NENF
2 serotonin binding GO:0051378 9.26 SLC6A4 HTR1A
3 FK506 binding GO:0005528 9.16 FKBP5 FKBP4
4 corticotropin-releasing hormone receptor activity GO:0043404 8.96 CRHR2 CRHR1
5 corticotrophin-releasing factor receptor activity GO:0015056 8.62 CRHR2 CRHR1

Sources for Acute Stress Disorder

9 Cosmic
10 dbSNP
11 DGIdb
17 EFO
18 ExPASy
19 FMA
28 GO
29 GTR
31 HPO
32 ICD10
33 ICD10 via Orphanet
37 LifeMap
41 MedGen
44 MeSH
45 MESH via Orphanet
46 MGI
49 NCI
50 NCIt
54 Novoseek
56 OMIM via Orphanet
57 OMIM® (Updated 05-Apr-2021)
61 PubMed
69 Tocris
71 UMLS via Orphanet
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