MCID: ACT060
MIFTS: 24

Acute Vascular Insufficiency of Intestine

Categories: Cardiovascular diseases, Gastrointestinal diseases

Aliases & Classifications for Acute Vascular Insufficiency of Intestine

MalaCards integrated aliases for Acute Vascular Insufficiency of Intestine:

Name: Acute Vascular Insufficiency of Intestine 12 15 71
Acute Gastrointestinal Tract Vascular Insuffic. 12
Acute Intestinal Vascular Insufficiency 12
Acute Git Vascular Insuffic. 12
Acute Intestinal Ischemia 12

Classifications:



External Ids:

Disease Ontology 12 DOID:8590
ICD9CM 34 557.0
NCIt 49 C34356
SNOMED-CT 67 91489000
UMLS 71 C0001363

Summaries for Acute Vascular Insufficiency of Intestine

MalaCards based summary : Acute Vascular Insufficiency of Intestine, also known as acute gastrointestinal tract vascular insuffic., is related to ischemia and thrombophilia due to thrombin defect. An important gene associated with Acute Vascular Insufficiency of Intestine is FABP2 (Fatty Acid Binding Protein 2), and among its related pathways/superpathways are PPAR signaling pathway and Tyrosine metabolism.

Related Diseases for Acute Vascular Insufficiency of Intestine

Diseases related to Acute Vascular Insufficiency of Intestine via text searches within MalaCards or GeneCards Suite gene sharing:

(show all 25)
# Related Disease Score Top Affiliating Genes
1 ischemia 10.7
2 thrombophilia due to thrombin defect 10.1
3 peritonitis 10.1
4 multinucleated neurons, anhydramnios, renal dysplasia, cerebellar hypoplasia, and hydranencephaly 10.0
5 thrombosis 10.0
6 gastrointestinal system disease 9.9
7 cardiac arrhythmia 9.8
8 ocular motor apraxia 9.8
9 encephalopathy, progressive, early-onset, with episodic rhabdomyolysis 9.8
10 metabolic acidosis 9.8
11 covid-19 9.8
12 endocarditis 9.8
13 short bowel syndrome 9.8
14 mesenteric vascular occlusion 9.8
15 toxic shock syndrome 9.8
16 neuroendocrine tumor 9.8
17 congestive heart failure 9.8
18 appendicitis 9.8
19 intestinal obstruction 9.8
20 spinal cord injury 9.8
21 jejunal neuroendocrine tumor 9.8
22 intracranial embolism 9.8 SERPINC1 OCLN
23 liver benign neoplasm 9.7 HPGDS GOT2
24 perinatal necrotizing enterocolitis 9.6 OCLN GOT2 FABP2
25 celiac disease 1 9.4 OCLN GOT2 FABP2

Comorbidity relations with Acute Vascular Insufficiency of Intestine via Phenotypic Disease Network (PDN): (show all 19)


Active Peptic Ulcer Disease Acute Cystitis
Acute Kidney Failure Acute Pancreatitis
Aortic Aneurysm Chronic Intestinal Vascular Insufficiency
Decubitus Ulcer Deficiency Anemia
Familial Atrial Fibrillation Heart Disease
Hypertension, Essential Intestinal Obstruction
Intestinal Perforation Paralytic Ileus
Peripheral Vascular Disease Peritonitis
Portal Vein Thrombosis Protein-Energy Malnutrition
Respiratory Failure

Graphical network of the top 20 diseases related to Acute Vascular Insufficiency of Intestine:



Diseases related to Acute Vascular Insufficiency of Intestine

Symptoms & Phenotypes for Acute Vascular Insufficiency of Intestine

Drugs & Therapeutics for Acute Vascular Insufficiency of Intestine

Interventional clinical trials:


# Name Status NCT ID Phase Drugs
1 Preoperative Findings on Non-specific CT in Patients With Primary Acute Intestinal Ischaemia; a Case-control Study Completed NCT04361110
2 Searching Biomarkers of Acute Intestinal Ischemic Injuries Recruiting NCT03518099

Search NIH Clinical Center for Acute Vascular Insufficiency of Intestine

Genetic Tests for Acute Vascular Insufficiency of Intestine

Anatomical Context for Acute Vascular Insufficiency of Intestine

Publications for Acute Vascular Insufficiency of Intestine

Articles related to Acute Vascular Insufficiency of Intestine:

# Title Authors PMID Year
1
Acute vascular insufficiency of intestine: incidence highest in summer, outcomes worst in winter. 61
31707559 2019
2
Ischemic colitis related to cocaine abuse. 61
8079939 1994
3
[Acute intestinal vascular insufficiency. Clinical-surgical study]. 61
5311669 1970

Variations for Acute Vascular Insufficiency of Intestine

Expression for Acute Vascular Insufficiency of Intestine

Search GEO for disease gene expression data for Acute Vascular Insufficiency of Intestine.

Pathways for Acute Vascular Insufficiency of Intestine

Pathways related to Acute Vascular Insufficiency of Intestine according to GeneCards Suite gene sharing:

# Super pathways Score Top Affiliating Genes
1 11.14 FABP6 FABP2
2
Show member pathways
11.04 GOT2 AOC1
3
Show member pathways
10.71 GOT2 AOC1
4
Show member pathways
10.29 GOT2 FABP2

GO Terms for Acute Vascular Insufficiency of Intestine

Biological processes related to Acute Vascular Insufficiency of Intestine according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 lactation GO:0007595 8.96 SERPINC1 GOT2
2 triglyceride catabolic process GO:0019433 8.62 FABP6 FABP2

Sources for Acute Vascular Insufficiency of Intestine

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
17 EFO
18 ExPASy
19 FMA
28 GO
29 GTR
30 HMDB
31 HPO
32 ICD10
33 ICD10 via Orphanet
34 ICD9CM
35 IUPHAR
36 KEGG
37 LifeMap
39 LOVD
41 MedGen
43 MeSH
44 MESH via Orphanet
45 MGI
48 NCI
49 NCIt
50 NDF-RT
53 NINDS
54 Novoseek
56 OMIM
57 OMIM via Orphanet
61 PubMed
63 QIAGEN
68 SNOMED-CT via HPO
69 TGDB
70 Tocris
71 UMLS
72 UMLS via Orphanet
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