AZOOR
MCID: ACT120
MIFTS: 25

Acute Zonal Occult Outer Retinopathy (AZOOR)

Categories: Eye diseases, Rare diseases

Aliases & Classifications for Acute Zonal Occult Outer Retinopathy

MalaCards integrated aliases for Acute Zonal Occult Outer Retinopathy:

Name: Acute Zonal Occult Outer Retinopathy 53 59 73
Azoor 53 59

Characteristics:

Orphanet epidemiological data:

59
acute zonal occult outer retinopathy
Inheritance: Not applicable; Age of onset: Adolescent,Adult;

Classifications:

MalaCards categories:
Global: Rare diseases
Anatomical: Eye diseases
Orphanet: 59  
Rare eye diseases


External Ids:

Orphanet 59 ORPHA284454
UMLS via Orphanet 74 C0730298
UMLS 73 C0730298

Summaries for Acute Zonal Occult Outer Retinopathy

NIH Rare Diseases : 53 Acute zonal occult outer retinopathy (AZOOR) is a rare condition that affects the eyes. People with this condition may experience a sudden onset of photopsia (the presence of perceived flashes of light) and an area of partial vision loss (a blindspot). Other symptoms may include "whitening of vision" or blurred vision. Although anyone can be affected, the condition is most commonly diagnosed in young women (average age 36.7 years). The underlying cause of AZOOR is currently unknown; however, some researchers have proposed that infectious agents (such as viruses) or autoimmunity may play a role in the development of the condition. No treatment has been proven to improve the visual outcome of AZOOR; however, systemic corticosteroids are the most commonly used therapy.

MalaCards based summary : Acute Zonal Occult Outer Retinopathy, also known as azoor, is related to choroiditis and multifocal choroiditis. An important gene associated with Acute Zonal Occult Outer Retinopathy is RLBP1 (Retinaldehyde Binding Protein 1), and among its related pathways/superpathways are Metabolism of fat-soluble vitamins and Visual Cycle in Retinal Rods. Affiliated tissues include eye, retina and prostate.

Wikipedia : 76 Acute zonal occult outer retinopathy (AZOOR) is an inflammatory retinopathy in the category of white dot... more...

Related Diseases for Acute Zonal Occult Outer Retinopathy

Graphical network of the top 20 diseases related to Acute Zonal Occult Outer Retinopathy:



Diseases related to Acute Zonal Occult Outer Retinopathy

Symptoms & Phenotypes for Acute Zonal Occult Outer Retinopathy

Drugs & Therapeutics for Acute Zonal Occult Outer Retinopathy

Interventional clinical trials:


# Name Status NCT ID Phase Drugs
1 New Non-invasive Modalities for Assessing Retinal Structure and Function Recruiting NCT03475173 Not Applicable

Search NIH Clinical Center for Acute Zonal Occult Outer Retinopathy

Genetic Tests for Acute Zonal Occult Outer Retinopathy

Anatomical Context for Acute Zonal Occult Outer Retinopathy

MalaCards organs/tissues related to Acute Zonal Occult Outer Retinopathy:

41
Eye, Retina, Prostate, T Cells

Publications for Acute Zonal Occult Outer Retinopathy

Articles related to Acute Zonal Occult Outer Retinopathy:

(show top 50) (show all 92)
# Title Authors Year
1
Treatment of Acute Zonal Occult Outer Retinopathy With Intravitreal Steroids. ( 30021037 )
2018
2
From A… to… Z(OOR): The Clinical Spectrum of Acute Zonal Occult Outer Retinopathy. ( 30042791 )
2018
3
Multimodal imaging signatures in a case of acute zonal occult outer retinopathy. ( 30127169 )
2018
4
Clinical course of acute zonal occult outer retinopathy complicated by choroidal neovascularization. ( 30181904 )
2018
5
Acute zonal occult outer retinopathy: Is optical coherence tomography angiography useful? ( 30355889 )
2018
6
Panoramic optical coherence tomography angiography features in acute zonal occult outer retinopathy. ( 30451199 )
2018
7
Multimodal imaging of acute zonal occult outer retinopathy in a Indian male. ( 30451200 )
2018
8
ACUTE ZONAL OCCULT OUTER RETINOPATHY: Structural and Functional Analysis Across the Transition Zone Between Healthy and Diseased Retina. ( 28590963 )
2017
9
Prevalence of Antiretinal Antibodies in Acute Zonal Occult Outer Retinopathy: A Comprehensive Review of 25 Cases. ( 28522028 )
2017
10
CHOROIDAL THICKNESS CHANGES IN ACUTE ZONAL OCCULT OUTER RETINOPATHY. ( 29160781 )
2017
11
Acute Zonal Occult Outer Retinopathy Associated With Retrobulbar Optic Neuritis. ( 28252457 )
2017
12
Relationship between Choroidal Thickness and Visual Field Impairment in Acute Zonal Occult Outer Retinopathy. ( 28758030 )
2017
13
Fundus Autofluorescence Imaging in the Assessment of Acute Zonal Occult Outer Retinopathy. ( 28245443 )
2017
14
Acute Zonal Occult Outer Retinopathy (AZOOR): a case report of vision improvement after intravitreal injection of Ozurdex. ( 29207977 )
2017
15
The clinical characteristics and prognosis of acute zonal occult outer retinopathy. ( 28573534 )
2017
16
Quantitative Autofluorescence Intensities in Acute Zonal Occult Outer Retinopathy vs Healthy Eyes. ( 29075777 )
2017
17
OCT Angiography Identification of Choroidal Neovascularization Secondary to Acute Zonal Occult Outer Retinopathy. ( 26731213 )
2016
18
Prevalence of anti-retinal antibodies in Acute Zonal Occult Outer Retinopathy (AZOOR): a comprehensive review of 25 cases. ( 27993590 )
2016
19
ACUTE ZONAL OCCULT OUTER RETINOPATHY AFFECTING THE PERIPHERAL RETINA WITH CENTRIPETAL PROGRESSION. ( 27243784 )
2016
20
ULTRA-WIDE-FIELD FUNDUS AUTOFLUORESCENCE FINDINGS IN PATIENTS WITH ACUTE ZONAL OCCULT OUTER RETINOPATHY. ( 27755372 )
2016
21
Pure small cell carcinoma of the prostate preceded by acute zonal occult outer retinopathy: A case report. ( 27693838 )
2016
22
AZOOR - A 10-year follow-up. ( 26581646 )
2016
23
Is Acute Zonal Occult Outer Retinopathy an Autoimmune Condition? A Case Report and Literature Review. ( 26114848 )
2015
24
Acute Zonal Occult Outer Retinopathy; Revisited. ( 26730303 )
2015
25
Acute zonal occult outer retinopathy in Japanese patients: clinical features, visual function, and factors affecting visual function. ( 25919689 )
2015
26
NEAR-INFRARED REFLECTANCE IMAGING IN EYES WITH ACUTE ZONAL OCCULT OUTER RETINOPATHY. ( 25923954 )
2015
27
Improved Photoreceptor Function in Male Acute Zonal Occult Outer Retinopathy. ( 26258275 )
2015
28
Systemic corticosteroids therapy in the management of acute zonal occult outer retinopathy. ( 25653869 )
2015
29
Changes in Outer Retinal Microstructures during Six Month Period in Eyes with Acute Zonal Occult Outer Retinopathy-Complex. ( 25356549 )
2014
30
Acute zonal occult outer retinopathy with atypical findings. ( 25140180 )
2014
31
Autologous antibodies to outer retina in acute zonal occult outer retinopathy. ( 25266678 )
2014
32
Acute zonal occult outer retinopathy: a classification based on multimodal imaging. ( 24945598 )
2014
33
Spontaneous remission of acute zonal occult outer retinopathy: follow-up using adaptive optics scanning laser ophthalmoscopy. ( 25081027 )
2014
34
A case of syphilitic outer retinitis mimicking acute zonal occult outer retinopathy. ( 25435755 )
2014
35
Successful treatment of an overlapping choriocapillaritis between multifocal choroiditis and acute zonal occult outer retinopathy (AZOOR) with adalimumab (Humira™). ( 23765682 )
2014
36
An optical coherence tomography and fundus autofluorescence imaging study of peripapillary acute zonal occult outer retinopathy. ( 23467270 )
2013
37
Two types of acute zonal occult outer retinopathy differentiated by dark- and light-adapted perimetry. ( 24368499 )
2013
38
Correlation between decreased choroidal blood flow velocity and the pathogenesis of acute zonal occult outer retinopathy. ( 23777505 )
2013
39
Photoreceptor outer segment abnormalities and retinal sensitivity in acute zonal occult outer retinopathy. ( 23135525 )
2013
40
Acute zonal occult outer retinopathy: vision loss in an active duty soldier. ( 23606850 )
2013
41
Changes in optical coherence tomography findings in acute zonal occult outer retinopathy. ( 24163675 )
2013
42
Long-term follow-up of acute zonal occult outer retinopathy. ( 23591538 )
2013
43
Imaging in the diagnosis and management of acute zonal occult outer retinopathy. ( 22954948 )
2012
44
Outer retinal structure in patients with acute zonal occult outer retinopathy. ( 22105799 )
2012
45
Improvement of central visual function following steroid pulse therapy in acute zonal occult outer retinopathy. ( 22402912 )
2012
46
Acute zonal occult outer retinopathy. ( 21056448 )
2011
47
Selective abnormality of cone outer segment tip line in acute zonal occult outer retinopathy as observed by spectral-domain optical coherence tomography. ( 21825201 )
2011
48
Focal functional and microstructural changes of photoreceptors in eyes with acute zonal occult outer retinopathy. ( 22125531 )
2011
49
Case of acute zonal occult outer retinopathy with abnormal pattern visual evoked potentials. ( 21966193 )
2011
50
Role of the OCT in the diagnosis of acute zonal occult outer retinopathy. ( 21484651 )
2011

Variations for Acute Zonal Occult Outer Retinopathy

Expression for Acute Zonal Occult Outer Retinopathy

Search GEO for disease gene expression data for Acute Zonal Occult Outer Retinopathy.

Pathways for Acute Zonal Occult Outer Retinopathy

Pathways related to Acute Zonal Occult Outer Retinopathy according to GeneCards Suite gene sharing:

# Super pathways Score Top Affiliating Genes
1
Show member pathways
11.49 RLBP1 SAG
2 10.6 RLBP1 SAG
3 10.32 RLBP1 SAG

GO Terms for Acute Zonal Occult Outer Retinopathy

Sources for Acute Zonal Occult Outer Retinopathy

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62 PubMed
64 QIAGEN
69 SNOMED-CT via HPO
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71 TGDB
72 Tocris
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74 UMLS via Orphanet
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