MCID: ACT120
MIFTS: 25

Acute Zonal Occult Outer Retinopathy

Categories: Rare diseases, Eye diseases

Aliases & Classifications for Acute Zonal Occult Outer Retinopathy

MalaCards integrated aliases for Acute Zonal Occult Outer Retinopathy:

Name: Acute Zonal Occult Outer Retinopathy 53 59 73
Azoor 53 59

Characteristics:

Orphanet epidemiological data:

59
acute zonal occult outer retinopathy
Inheritance: Not applicable; Age of onset: Adolescent,Adult;

Classifications:

MalaCards categories:
Global: Rare diseases
Anatomical: Eye diseases
Orphanet: 59  
Rare eye diseases


External Ids:

Orphanet 59 ORPHA284454
UMLS via Orphanet 74 C0730298
UMLS 73 C0730298

Summaries for Acute Zonal Occult Outer Retinopathy

NIH Rare Diseases : 53 Acute zonal occult outer retinopathy (AZOOR) is a rare condition that affects the eyes. People with this condition may experience a sudden onset of photopsia (the presence of perceived flashes of light) and an area of partial vision loss (a blindspot). Other symptoms may include "whitening of vision" or blurred vision. Although anyone can be affected, the condition is most commonly diagnosed in young women (average age 36.7 years). The underlying cause of AZOOR is currently unknown; however, some researchers have proposed that infectious agents (such as viruses) or autoimmunity may play a role in the development of the condition. No treatment has been proven to improve the visual outcome of AZOOR; however, systemic corticosteroids are the most commonly used therapy.

MalaCards based summary : Acute Zonal Occult Outer Retinopathy, also known as azoor, is related to retinitis and choroiditis. An important gene associated with Acute Zonal Occult Outer Retinopathy is RLBP1 (Retinaldehyde Binding Protein 1), and among its related pathways/superpathways are Metabolism of fat-soluble vitamins and Visual Cycle in Retinal Rods. Affiliated tissues include eye, retina and prostate.

Wikipedia : 76 Acute zonal occult outer retinopathy (AZOOR) is an inflammatory retinopathy in the category of white dot... more...

Related Diseases for Acute Zonal Occult Outer Retinopathy

Diseases related to Acute Zonal Occult Outer Retinopathy via text searches within MalaCards or GeneCards Suite gene sharing:

(show all 23)
# Related Disease Score Top Affiliating Genes
1 retinitis 10.5
2 choroiditis 10.5
3 multifocal choroiditis 10.2
4 punctate inner choroidopathy 10.2
5 autoimmune disease 10.1
6 multiple sclerosis 10.1
7 polycythemia vera 10.1
8 aging 10.1
9 pars planitis 10.1
10 autoimmune disease 1 10.1
11 alpha/beta t-cell lymphopenia with gamma/delta t-cell expansion, severe cytomegalovirus infection, and autoimmunity 10.1
12 graft-versus-host disease 10.1
13 small cell carcinoma 10.1
14 optic neuritis 10.1
15 prostatitis 10.1
16 neuritis 10.1
17 polycythemia 10.1
18 serpiginous choroiditis 10.1
19 acute annular outer retinopathy 10.1
20 fundus albipunctatus 9.4 RLBP1 SAG
21 retinal disease 9.3 RLBP1 SAG
22 retinal degeneration 9.2 RLBP1 SAG
23 retinitis pigmentosa 9.0 RLBP1 SAG

Graphical network of the top 20 diseases related to Acute Zonal Occult Outer Retinopathy:



Diseases related to Acute Zonal Occult Outer Retinopathy

Symptoms & Phenotypes for Acute Zonal Occult Outer Retinopathy

Drugs & Therapeutics for Acute Zonal Occult Outer Retinopathy

Interventional clinical trials:


# Name Status NCT ID Phase Drugs
1 New Non-invasive Modalities for Assessing Retinal Structure and Function Recruiting NCT03475173 Not Applicable

Search NIH Clinical Center for Acute Zonal Occult Outer Retinopathy

Genetic Tests for Acute Zonal Occult Outer Retinopathy

Anatomical Context for Acute Zonal Occult Outer Retinopathy

MalaCards organs/tissues related to Acute Zonal Occult Outer Retinopathy:

41
Eye, Retina, Prostate

Publications for Acute Zonal Occult Outer Retinopathy

Articles related to Acute Zonal Occult Outer Retinopathy:

(show top 50) (show all 80)
# Title Authors Year
1
ACUTE ZONAL OCCULT OUTER RETINOPATHY: Structural and Functional Analysis Across the Transition Zone Between Healthy and Diseased Retina. ( 28590963 )
2017
2
Prevalence of Antiretinal Antibodies in Acute Zonal Occult Outer Retinopathy: A Comprehensive Review of 25 Cases. ( 28522028 )
2017
3
CHOROIDAL THICKNESS CHANGES IN ACUTE ZONAL OCCULT OUTER RETINOPATHY. ( 29160781 )
2017
4
Acute Zonal Occult Outer Retinopathy Associated With Retrobulbar Optic Neuritis. ( 28252457 )
2017
5
Relationship between Choroidal Thickness and Visual Field Impairment in Acute Zonal Occult Outer Retinopathy. ( 28758030 )
2017
6
Fundus Autofluorescence Imaging in the Assessment of Acute Zonal Occult Outer Retinopathy. ( 28245443 )
2017
7
Acute Zonal Occult Outer Retinopathy (AZOOR): a case report of vision improvement after intravitreal injection of Ozurdex. ( 29207977 )
2017
8
The clinical characteristics and prognosis of acute zonal occult outer retinopathy. ( 28573534 )
2017
9
Quantitative Autofluorescence Intensities in Acute Zonal Occult Outer Retinopathy vs Healthy Eyes. ( 29075777 )
2017
10
OCT Angiography Identification of Choroidal Neovascularization Secondary to Acute Zonal Occult Outer Retinopathy. ( 26731213 )
2016
11
Prevalence of anti-retinal antibodies in Acute Zonal Occult Outer Retinopathy (AZOOR): a comprehensive review of 25 cases. ( 27993590 )
2016
12
ACUTE ZONAL OCCULT OUTER RETINOPATHY AFFECTING THE PERIPHERAL RETINA WITH CENTRIPETAL PROGRESSION. ( 27243784 )
2016
13
ULTRA-WIDE-FIELD FUNDUS AUTOFLUORESCENCE FINDINGS IN PATIENTS WITH ACUTE ZONAL OCCULT OUTER RETINOPATHY. ( 27755372 )
2016
14
Pure small cell carcinoma of the prostate preceded by acute zonal occult outer retinopathy: A case report. ( 27693838 )
2016
15
Is Acute Zonal Occult Outer Retinopathy an Autoimmune Condition? A Case Report and Literature Review. ( 26114848 )
2015
16
Acute Zonal Occult Outer Retinopathy; Revisited. ( 26730303 )
2015
17
Acute zonal occult outer retinopathy in Japanese patients: clinical features, visual function, and factors affecting visual function. ( 25919689 )
2015
18
NEAR-INFRARED REFLECTANCE IMAGING IN EYES WITH ACUTE ZONAL OCCULT OUTER RETINOPATHY. ( 25923954 )
2015
19
Improved Photoreceptor Function in Male Acute Zonal Occult Outer Retinopathy. ( 26258275 )
2015
20
Systemic corticosteroids therapy in the management of acute zonal occult outer retinopathy. ( 25653869 )
2015
21
Changes in Outer Retinal Microstructures during Six Month Period in Eyes with Acute Zonal Occult Outer Retinopathy-Complex. ( 25356549 )
2014
22
Acute zonal occult outer retinopathy with atypical findings. ( 25140180 )
2014
23
Autologous antibodies to outer retina in acute zonal occult outer retinopathy. ( 25266678 )
2014
24
Acute zonal occult outer retinopathy: a classification based on multimodal imaging. ( 24945598 )
2014
25
Spontaneous remission of acute zonal occult outer retinopathy: follow-up using adaptive optics scanning laser ophthalmoscopy. ( 25081027 )
2014
26
A case of syphilitic outer retinitis mimicking acute zonal occult outer retinopathy. ( 25435755 )
2014
27
An optical coherence tomography and fundus autofluorescence imaging study of peripapillary acute zonal occult outer retinopathy. ( 23467270 )
2013
28
Two types of acute zonal occult outer retinopathy differentiated by dark- and light-adapted perimetry. ( 24368499 )
2013
29
Correlation between decreased choroidal blood flow velocity and the pathogenesis of acute zonal occult outer retinopathy. ( 23777505 )
2013
30
Photoreceptor outer segment abnormalities and retinal sensitivity in acute zonal occult outer retinopathy. ( 23135525 )
2013
31
Acute zonal occult outer retinopathy: vision loss in an active duty soldier. ( 23606850 )
2013
32
Changes in optical coherence tomography findings in acute zonal occult outer retinopathy. ( 24163675 )
2013
33
Long-term follow-up of acute zonal occult outer retinopathy. ( 23591538 )
2013
34
Successful treatment of an overlapping choriocapillaritis between multifocal choroiditis and acute zonal occult outer retinopathy (AZOOR) with adalimumab (Humiraa8c). ( 23765682 )
2013
35
Imaging in the diagnosis and management of acute zonal occult outer retinopathy. ( 22954948 )
2012
36
Outer retinal structure in patients with acute zonal occult outer retinopathy. ( 22105799 )
2012
37
Improvement of central visual function following steroid pulse therapy in acute zonal occult outer retinopathy. ( 22402912 )
2012
38
Acute zonal occult outer retinopathy. ( 21056448 )
2011
39
Selective abnormality of cone outer segment tip line in acute zonal occult outer retinopathy as observed by spectral-domain optical coherence tomography. ( 21825201 )
2011
40
Focal functional and microstructural changes of photoreceptors in eyes with acute zonal occult outer retinopathy. ( 22125531 )
2011
41
Case of acute zonal occult outer retinopathy with abnormal pattern visual evoked potentials. ( 21966193 )
2011
42
Role of the OCT in the diagnosis of acute zonal occult outer retinopathy. ( 21484651 )
2011
43
Simultaneous presentation of multifocal choroiditis and acute zonal occult outer retinopathy in one eye. ( 19474000 )
2011
44
[Blind spot enlargement syndrome in acute zonal occult outer retinopathy with detection of autoantibodies against the retinal antigens CRALBP and S-Ag]. ( 21904838 )
2011
45
Acute progression of electrophysiologically affected fellow eye in unilaterally symptomatic acute zonal occult outer retinopathy. ( 21887099 )
2011
46
Patients with an acute zonal occult outer retinopathy-like illness rapidly improve with valacyclovir treatment. ( 20691421 )
2010
47
Acute zonal occult outer retinopathy: a case report. ( 20004874 )
2010
48
Polycythemia vera and increased hemophilic factor VIII causing acute zonal occult outer retinopathy: a case report. ( 20662663 )
2010
49
Fundus autofluorescence and optical coherence tomographic findings in acute zonal occult outer retinopathy. ( 20661173 )
2010
50
Acute zonal occult outer retinopathy in patients with multiple evanescent white dot syndrome. ( 19139340 )
2009

Variations for Acute Zonal Occult Outer Retinopathy

Expression for Acute Zonal Occult Outer Retinopathy

Search GEO for disease gene expression data for Acute Zonal Occult Outer Retinopathy.

Pathways for Acute Zonal Occult Outer Retinopathy

Pathways related to Acute Zonal Occult Outer Retinopathy according to GeneCards Suite gene sharing:

# Super pathways Score Top Affiliating Genes
1
Show member pathways
11.29 RLBP1 SAG
2 10.6 RLBP1 SAG

GO Terms for Acute Zonal Occult Outer Retinopathy

Sources for Acute Zonal Occult Outer Retinopathy

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
17 ExPASy
19 FMA
28 GO
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30 HGMD
31 HMDB
32 HPO
33 ICD10
34 ICD10 via Orphanet
35 ICD9CM
36 IUPHAR
37 KEGG
38 LifeMap
40 LOVD
42 MedGen
44 MeSH
45 MESH via Orphanet
46 MGI
49 NCI
50 NCIt
51 NDF-RT
54 NINDS
55 Novoseek
57 OMIM
58 OMIM via Orphanet
62 PubMed
64 QIAGEN
69 SNOMED-CT via HPO
70 SNOMED-CT via Orphanet
71 TGDB
72 Tocris
73 UMLS
74 UMLS via Orphanet
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