MCID: ADM001
MIFTS: 26

Adamantinous Craniopharyngioma

Categories: Cancer diseases, Neuronal diseases

Aliases & Classifications for Adamantinous Craniopharyngioma

MalaCards integrated aliases for Adamantinous Craniopharyngioma:

Name: Adamantinous Craniopharyngioma 12 15 73
Craniopharyngioma, Adamantinomatous 12
Adamantinous Rathke's Pouch Tumor 12

Classifications:



External Ids:

Disease Ontology 12 DOID:3846
MeSH 44 D003397
NCIt 50 C4726
SNOMED-CT 68 128781004 134216001
UMLS 73 C0431129

Summaries for Adamantinous Craniopharyngioma

MalaCards based summary : Adamantinous Craniopharyngioma, also known as craniopharyngioma, adamantinomatous, is related to angiokeratoma circumscriptum and sick building syndrome, and has symptoms including visual disturbance An important gene associated with Adamantinous Craniopharyngioma is MMP9 (Matrix Metallopeptidase 9), and among its related pathways/superpathways are G-Beta Gamma Signaling and Kaposi's sarcoma-associated herpesvirus infection. Affiliated tissues include endothelial.

Related Diseases for Adamantinous Craniopharyngioma

Diseases related to Adamantinous Craniopharyngioma via text searches within MalaCards or GeneCards Suite gene sharing:

(show all 33)
# Related Disease Score Top Affiliating Genes
1 angiokeratoma circumscriptum 10.6 MMP9 VEGFA
2 sick building syndrome 10.6 MMP9 VEGFA
3 microcystic meningioma 10.6 MMP9 VEGFA
4 adenomyosis 10.6 MMP9 VEGFA
5 odontogenic myxoma 10.5 MMP9 VEGFA
6 tuberculous meningitis 10.5 MMP9 VEGFA
7 rosacea 10.5 MMP9 VEGFA
8 arteriovenous malformation 10.5 MMP9 VEGFA
9 pharynx cancer 10.5 MMP9 VEGFA
10 keratitis, hereditary 10.4 MMP9 VEGFA
11 severe pre-eclampsia 10.4 MMP9 VEGFA
12 psammomatous meningioma 10.4 CTNNB1 MMP9
13 microvascular complications of diabetes 1 10.4 MMP9 VEGFA
14 grade iii astrocytoma 10.3 MMP9 VEGFA
15 brain edema 10.2 MMP9 VEGFA
16 varicose veins 10.1 MMP9 VEGFA
17 exudative vitreoretinopathy 1 10.1 CTNNB1 VEGFA
18 craniopharyngioma 10.1
19 endotheliitis 10.1
20 male reproductive organ cancer 10.0 MMP9 VEGFA
21 female reproductive organ cancer 10.0 CTNNB1 MMP9 VEGFA
22 respiratory system cancer 10.0 CTNNB1 MMP9 VEGFA
23 cell type cancer 10.0 CTNNB1 MMP9 VEGFA
24 gastrointestinal system cancer 10.0 CTNNB1 MMP9 VEGFA
25 adamantinoma of long bones 10.0 CTNNB1 MMP9 VEGFA
26 squamous cell carcinoma, head and neck 9.9 CTNNB1 MMP9 VEGFA
27 lung cancer susceptibility 3 9.9 CTNNB1 MMP9 VEGFA
28 gastric adenocarcinoma 9.9 CTNNB1 MMP9 VEGFA
29 cholangiocarcinoma 9.8 CTNNB1 MMP9 VEGFA
30 nasopharyngeal carcinoma 9.8 CTNNB1 MMP9 VEGFA
31 colorectal adenocarcinoma 9.6 CTNNB1 VEGFA
32 papillary craniopharyngioma 9.3 CTNNB1 DNAH12 DNAH2 DNAH7
33 central nervous system organ benign neoplasm 9.2 CTNNB1 DNAH2 DNAH7 HESX1

Graphical network of the top 20 diseases related to Adamantinous Craniopharyngioma:



Diseases related to Adamantinous Craniopharyngioma

Symptoms & Phenotypes for Adamantinous Craniopharyngioma

UMLS symptoms related to Adamantinous Craniopharyngioma:


visual disturbance

Drugs & Therapeutics for Adamantinous Craniopharyngioma

Search Clinical Trials , NIH Clinical Center for Adamantinous Craniopharyngioma

Genetic Tests for Adamantinous Craniopharyngioma

Anatomical Context for Adamantinous Craniopharyngioma

MalaCards organs/tissues related to Adamantinous Craniopharyngioma:

41
Endothelial

Publications for Adamantinous Craniopharyngioma

Articles related to Adamantinous Craniopharyngioma:

# Title Authors Year
1
Expression of matrix metalloproteinase-9, type IV collagen and vascular endothelial growth factor in adamantinous craniopharyngioma. ( 21814723 )
2011

Variations for Adamantinous Craniopharyngioma

Expression for Adamantinous Craniopharyngioma

Search GEO for disease gene expression data for Adamantinous Craniopharyngioma.

Pathways for Adamantinous Craniopharyngioma

GO Terms for Adamantinous Craniopharyngioma

Cellular components related to Adamantinous Craniopharyngioma according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 cytoskeleton GO:0005856 9.65 CTNNB1 DNAH12 DNAH2 DNAH7 TUBA4A
2 cilium GO:0005929 9.5 DNAH12 DNAH2 DNAH7
3 microtubule GO:0005874 9.26 DNAH12 DNAH2 DNAH7 TUBA4A
4 axonemal dynein complex GO:0005858 9.16 DNAH2 DNAH7
5 dynein complex GO:0030286 8.8 DNAH12 DNAH2 DNAH7

Biological processes related to Adamantinous Craniopharyngioma according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 vasculogenesis GO:0001570 9.43 CTNNB1 VEGFA
2 cell maturation GO:0048469 9.4 CTNNB1 VEGFA
3 branching involved in blood vessel morphogenesis GO:0001569 9.37 CTNNB1 VEGFA
4 positive regulation of mesenchymal cell proliferation GO:0002053 9.32 CTNNB1 VEGFA
5 positive regulation of neuroblast proliferation GO:0002052 9.26 CTNNB1 VEGFA
6 macrophage differentiation GO:0030225 9.16 MMP9 VEGFA
7 cilium-dependent cell motility GO:0060285 8.96 DNAH2 DNAH7
8 microtubule-based movement GO:0007018 8.8 DNAH12 DNAH2 DNAH7

Molecular functions related to Adamantinous Craniopharyngioma according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 dynein light intermediate chain binding GO:0051959 9.37 DNAH2 DNAH7
2 dynein intermediate chain binding GO:0045505 9.32 DNAH2 DNAH7
3 dynein light chain binding GO:0045503 9.26 DNAH2 DNAH7
4 ATP-dependent microtubule motor activity, minus-end-directed GO:0008569 9.16 DNAH2 DNAH7
5 microtubule motor activity GO:0003777 9.13 DNAH12 DNAH2 DNAH7
6 motor activity GO:0003774 8.8 DNAH12 DNAH2 DNAH7

Sources for Adamantinous Craniopharyngioma

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
17 ExPASy
19 FMA
28 GO
29 GTR
30 HGMD
31 HMDB
32 HPO
33 ICD10
34 ICD10 via Orphanet
35 ICD9CM
36 IUPHAR
37 KEGG
38 LifeMap
40 LOVD
42 MedGen
44 MeSH
45 MESH via Orphanet
46 MGI
49 NCI
50 NCIt
51 NDF-RT
54 NINDS
55 Novoseek
57 OMIM
58 OMIM via Orphanet
62 PubMed
64 QIAGEN
69 SNOMED-CT via HPO
70 SNOMED-CT via Orphanet
71 TGDB
72 Tocris
73 UMLS
74 UMLS via Orphanet
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