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MCID: ADN018
MIFTS: 58

Adenoma

Categories: Cancer diseases, Endocrine diseases
Genes Tissues Related diseases Publications Pathways Drugs
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Aliases & Classifications for Adenoma

About this section

MalaCards integrated aliases for Adenoma:

Name: Adenoma 12 74 54 15 71
Acinar Cell Adenoma 12 71
Adenomas 12 15
Acinic Cell Adenoma 12

Classifications:

MalaCards categories:
Global: Cancer diseases
Anatomical: Endocrine diseases
See all MalaCards categories (disease lists)


External Ids:

Disease Ontology 12 DOID:657
MeSH 43 D000236
NCIt 49 C2855 C4196
SNOMED-CT 67 32048006 79041005
UMLS 71 C0001430 C0334389
Sources

Summaries for Adenoma

About this section
Disease Ontology : 12 A cell type benign neoplasm that is composed of epithelial tissue in which tumor cells form glands or glandlike structures.

MalaCards based summary : Adenoma, also known as acinar cell adenoma, is related to acth-secreting pituitary adenoma and familial isolated pituitary adenoma. An important gene associated with Adenoma is PLAG1 (PLAG1 Zinc Finger), and among its related pathways/superpathways are Signaling by GPCR and Toll-like Receptor Signaling Pathway. The drugs Linaclotide and Scopolamine have been mentioned in the context of this disorder. Affiliated tissues include pituitary, thyroid and colon, and related phenotypes are Increased shRNA abundance (Z-score > 2) and Increased shRNA abundance (Z-score > 2)

Wikipedia : 74 An adenoma is a benign tumor of epithelial tissue with glandular origin, glandular characteristics, or... more...

Sources

Related Diseases for Adenoma

About this section

Diseases related to Adenoma via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50) (show all 1747)
# Related Disease Score Top Affiliating Genes
1 acth-secreting pituitary adenoma 35.0 MEN1 GNAS AIP
2 familial isolated pituitary adenoma 35.0 MEN1 AIP
3 pituitary adenoma, prolactin-secreting 34.9 MEN1 GNAS AIP
4 colorectal adenoma 34.7 MSH2 MLH1 KRAS CTNNB1 CCND1 APC
5 parathyroid adenoma 34.7 RET MEN1 GNAS CTNNB1 CDC73 CCND1
6 pleomorphic adenoma 34.7 PLAGL2 PLAG1 CTNNB1
7 villous adenoma 34.7 MLH1 KRAS GNAS BRAF APC
8 growth hormone secreting pituitary adenoma 34.6 MEN1 GNAS AIP
9 functioning pituitary adenoma 34.5 MEN1 GNAS AIP
10 apocrine adenoma 34.4 KRAS BRAF
11 follicular adenoma 34.4 TSHR RET MEN1 GNAS BRAF
12 extrahepatic bile duct adenoma 34.3 MSH2 MLH1
13 periampullary adenoma 34.3 KRAS APC
14 silent pituitary adenoma 34.3 MEN1 AIP
15 colon adenoma 34.2 SMAD4 KRAS APC
16 cervical adenoma malignum 34.2 MSH2 MLH1
17 sebaceous adenoma 34.1 MSH2 MLH1
18 null pituitary adenoma 34.1 MEN1 AIP
19 polyposis syndrome, hereditary mixed, 1 34.1 MLH1 APC
20 hyperparathyroidism 2 with jaw tumors 33.9 RET MEN1 CDC73 CCND1
21 hyperparathyroidism 1 33.9 MEN1 CDC73
22 carney complex variant 33.5 RET MEN1 GNAS AIP
23 primary hyperparathyroidism 33.3 RET MEN1 GNAS CDC73 CCND1
24 multiple endocrine neoplasia, type i 33.3 RET MEN1 GNAS CDC73 AIP
25 familial adenomatous polyposis 1 33.3 CTNNB1 APC
26 mismatch repair cancer syndrome 33.3 MSH2 MLH1 CTNNB1 APC
27 parathyroid carcinoma 33.2 RET MEN1 CDC73 CCND1 APC
28 endometrial adenocarcinoma 33.2 MLH1 KRAS CTNNB1 CCND1
29 adrenal carcinoma 33.1 MEN1 CTNNB1 CCND1
30 appendix adenocarcinoma 33.1 KRAS GNAS
31 primary pigmented nodular adrenocortical disease 33.1 MEN1 GNAS CTNNB1
32 myh-associated polyposis 33.1 MSH2 KRAS APC
33 familial adenomatous polyposis 33.0 SMAD4 MSH2 MLH1 KRAS CTNNB1 CCND1
34 multiple endocrine neoplasia, type iia 33.0 RET MEN1 CDC73
35 juvenile polyposis syndrome 33.0 SMAD4 MSH2 MLH1 APC
36 hyperpituitarism 32.9 MEN1 GNAS AIP
37 gastric cancer 32.5 SMAD4 MSH2 MLH1 KRAS CTNNB1 CCND1
38 thyroid carcinoma 32.0 TSHR RET CTNNB1 BRAF
39 goiter 31.9 TSHR RET GNAS
40 adenocarcinoma 31.8 SMAD4 RET MSH2 MLH1 KRAS GNAS
41 papillary carcinoma 31.7 TSHR RET GNAS BRAF
42 neuroblastoma 31.7 RET MSH2 MEN1 CTNNB1 CCND1 AXIN2
43 hormone producing pituitary cancer 31.6 MEN1 GNAS AIP
44 craniopharyngioma 31.5 CTNNB1 BRAF APC
45 thyroiditis 31.4 TSHR RET BRAF
46 rectum cancer 31.4 MSH2 MLH1 KRAS APC
47 adrenocortical carcinoma, hereditary 31.4 GNAS CTNNB1 BRAF
48 peutz-jeghers syndrome 31.4 SMAD4 GNAS CTNNB1 APC
49 nodular goiter 31.4 TSHR RET BRAF
50 ulcerative colitis 31.4 SMAD4 MSH2 MLH1 CTNNB1

Graphical network of the top 20 diseases related to Adenoma:



Diseases related to Adenoma
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Symptoms & Phenotypes for Adenoma

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GenomeRNAi Phenotypes related to Adenoma according to GeneCards Suite gene sharing:

26 (show top 50) (show all 72)
# Description GenomeRNAi Source Accession Score Top Affiliating Genes
1 Increased shRNA abundance (Z-score > 2) GR00366-A-107 10.86 SMAD4
2 Increased shRNA abundance (Z-score > 2) GR00366-A-110 10.86 PLAGL2 BRAF
3 Increased shRNA abundance (Z-score > 2) GR00366-A-113 10.86 CTNNB1
4 Increased shRNA abundance (Z-score > 2) GR00366-A-115 10.86 MEN1
5 Increased shRNA abundance (Z-score > 2) GR00366-A-120 10.86 KRAS
6 Increased shRNA abundance (Z-score > 2) GR00366-A-122 10.86 MEN1
7 Increased shRNA abundance (Z-score > 2) GR00366-A-124 10.86 MLH1 PLAG1
8 Increased shRNA abundance (Z-score > 2) GR00366-A-126 10.86 CCND1
9 Increased shRNA abundance (Z-score > 2) GR00366-A-127 10.86 PLAGL2
10 Increased shRNA abundance (Z-score > 2) GR00366-A-128 10.86 MEN1
11 Increased shRNA abundance (Z-score > 2) GR00366-A-132 10.86 RET
12 Increased shRNA abundance (Z-score > 2) GR00366-A-133 10.86 APC
13 Increased shRNA abundance (Z-score > 2) GR00366-A-138 10.86 MLH1
14 Increased shRNA abundance (Z-score > 2) GR00366-A-146 10.86 PLAGL2
15 Increased shRNA abundance (Z-score > 2) GR00366-A-149 10.86 BRAF
16 Increased shRNA abundance (Z-score > 2) GR00366-A-151 10.86 PLAG1
17 Increased shRNA abundance (Z-score > 2) GR00366-A-152 10.86 CCND1
18 Increased shRNA abundance (Z-score > 2) GR00366-A-16 10.86 CCND1
19 Increased shRNA abundance (Z-score > 2) GR00366-A-163 10.86 CCND1
20 Increased shRNA abundance (Z-score > 2) GR00366-A-164 10.86 RET
21 Increased shRNA abundance (Z-score > 2) GR00366-A-166 10.86 BRAF
22 Increased shRNA abundance (Z-score > 2) GR00366-A-168 10.86 KRAS
23 Increased shRNA abundance (Z-score > 2) GR00366-A-176 10.86 RET
24 Increased shRNA abundance (Z-score > 2) GR00366-A-177 10.86 APC CTNNB1 CCND1 KRAS MEN1 BRAF
25 Increased shRNA abundance (Z-score > 2) GR00366-A-191 10.86 CTNNB1
26 Increased shRNA abundance (Z-score > 2) GR00366-A-192 10.86 APC
27 Increased shRNA abundance (Z-score > 2) GR00366-A-194 10.86 BRAF
28 Increased shRNA abundance (Z-score > 2) GR00366-A-196 10.86 KRAS
29 Increased shRNA abundance (Z-score > 2) GR00366-A-197 10.86 CTNNB1
30 Increased shRNA abundance (Z-score > 2) GR00366-A-199 10.86 CCND1
31 Increased shRNA abundance (Z-score > 2) GR00366-A-200 10.86 MLH1
32 Increased shRNA abundance (Z-score > 2) GR00366-A-202 10.86 APC
33 Increased shRNA abundance (Z-score > 2) GR00366-A-207 10.86 PLAG1
34 Increased shRNA abundance (Z-score > 2) GR00366-A-21 10.86 SMAD4 CCND1
35 Increased shRNA abundance (Z-score > 2) GR00366-A-210 10.86 CCND1
36 Increased shRNA abundance (Z-score > 2) GR00366-A-211 10.86 CCND1
37 Increased shRNA abundance (Z-score > 2) GR00366-A-23 10.86 KRAS
38 Increased shRNA abundance (Z-score > 2) GR00366-A-25 10.86 SMAD4 CCND1 PLAGL2 RET
39 Increased shRNA abundance (Z-score > 2) GR00366-A-29 10.86 APC BRAF
40 Increased shRNA abundance (Z-score > 2) GR00366-A-31 10.86 BRAF
41 Increased shRNA abundance (Z-score > 2) GR00366-A-32 10.86 BRAF
42 Increased shRNA abundance (Z-score > 2) GR00366-A-36 10.86 CCND1
43 Increased shRNA abundance (Z-score > 2) GR00366-A-42 10.86 SMAD4
44 Increased shRNA abundance (Z-score > 2) GR00366-A-43 10.86 SMAD4 MEN1
45 Increased shRNA abundance (Z-score > 2) GR00366-A-46 10.86 SMAD4
46 Increased shRNA abundance (Z-score > 2) GR00366-A-47 10.86 CTNNB1 MEN1 BRAF
47 Increased shRNA abundance (Z-score > 2) GR00366-A-49 10.86 APC CTNNB1 KRAS MEN1 PLAG1
48 Increased shRNA abundance (Z-score > 2) GR00366-A-50 10.86 KRAS
49 Increased shRNA abundance (Z-score > 2) GR00366-A-52 10.86 RET
50 Increased shRNA abundance (Z-score > 2) GR00366-A-54 10.86 SMAD4

MGI Mouse Phenotypes related to Adenoma:

45 (show all 24)
# Description MGI Source Accession Score Top Affiliating Genes
1 cellular MP:0005384 10.54 AIP APC AXIN2 BRAF CCND1 CDC73
2 endocrine/exocrine gland MP:0005379 10.51 AIP APC AXIN2 BRAF CCND1 CDC73
3 growth/size/body region MP:0005378 10.51 AIP APC AXIN2 BRAF CCND1 CDC73
4 homeostasis/metabolism MP:0005376 10.5 AIP APC AXIN2 BRAF CCND1 CDC73
5 digestive/alimentary MP:0005381 10.47 APC AXIN2 BRAF CCND1 CDC73 CTNNB1
6 cardiovascular system MP:0005385 10.43 AIP APC AXIN2 BRAF CCND1 CDC73
7 mortality/aging MP:0010768 10.41 AIP APC AXIN2 BRAF CCND1 CDC73
8 hematopoietic system MP:0005397 10.4 APC BRAF CCND1 CDC73 CTNNB1 GNAS
9 immune system MP:0005387 10.38 APC BRAF CCND1 CDC73 CTNNB1 GNAS
10 embryo MP:0005380 10.33 AIP APC AXIN2 BRAF CDC73 CTNNB1
11 craniofacial MP:0005382 10.3 APC AXIN2 BRAF CCND1 CDC73 CTNNB1
12 integument MP:0010771 10.3 AIP APC AXIN2 BRAF CCND1 CDC73
13 neoplasm MP:0002006 10.28 AIP APC BRAF CCND1 CDC73 CTNNB1
14 nervous system MP:0003631 10.25 APC AXIN2 BRAF CCND1 CDC73 CTNNB1
15 liver/biliary system MP:0005370 10.19 AIP APC BRAF CDC73 CTNNB1 GNAS
16 limbs/digits/tail MP:0005371 10.16 APC AXIN2 BRAF CTNNB1 GNAS KRAS
17 muscle MP:0005369 10.11 APC BRAF CDC73 CTNNB1 GNAS KRAS
18 reproductive system MP:0005389 10.1 APC AXIN2 BRAF CCND1 CDC73 CTNNB1
19 hearing/vestibular/ear MP:0005377 10.04 APC BRAF CTNNB1 GNAS KRAS TSHR
20 normal MP:0002873 10.02 APC AXIN2 BRAF CCND1 CTNNB1 GNAS
21 renal/urinary system MP:0005367 9.97 APC BRAF CDC73 CTNNB1 GNAS KRAS
22 respiratory system MP:0005388 9.81 BRAF CCND1 CDC73 CTNNB1 GNAS KRAS
23 skeleton MP:0005390 9.65 APC AXIN2 BRAF CCND1 CDC73 CTNNB1
24 vision/eye MP:0005391 9.28 APC AXIN2 BRAF CCND1 CTNNB1 KRAS
Sources

Drugs & Therapeutics for Adenoma

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Drugs for Adenoma (from DrugBank, HMDB, Dgidb, PharmGKB, IUPHAR, NovoSeek, BitterDB):

(show top 50) (show all 466)
# Name Status Phase Clinical Trials Cas Number PubChem Id
1
Linaclotide Approved Phase 4 851199-59-2 65351
2
Scopolamine Approved, Investigational Phase 4 51-34-3, 6533-68-2 5184
3
Erythromycin Approved, Investigational, Vet_approved Phase 4 114-07-8 12560 441411
4
Dyclonine Approved Phase 4 586-60-7 3180
5
Pantoprazole Approved Phase 4 102625-70-7 4679
6
Clarithromycin Approved Phase 4 81103-11-9 84029
7
Prednisone Approved, Vet_approved Phase 4 53-03-2 5865
8
Clopidogrel Approved Phase 4 120202-66-6, 113665-84-2 60606
9
Prucalopride Approved Phase 4 179474-81-8
10
Lansoprazole Approved, Investigational Phase 4 103577-45-3 3883
11
Dexlansoprazole Approved, Investigational Phase 4 138530-94-6, 103577-45-3 9578005
12
Metronidazole Approved Phase 4 443-48-1 4173
13
Amoxicillin Approved, Vet_approved Phase 4 26787-78-0 33613
14
Pasireotide Approved Phase 4 396091-73-9 9941444
15
Metformin Approved Phase 4 657-24-9 14219 4091
16
Methylene blue Approved, Investigational Phase 4 61-73-4
17
Rabeprazole Approved, Investigational Phase 4 117976-89-3 5029
18
Magnesium citrate Approved Phase 4 3344-18-1
19
Sodium citrate Approved, Investigational Phase 4 68-04-2
20
Glucagon Approved Phase 4 16941-32-5
21
Alendronate Approved Phase 4 121268-17-5, 66376-36-1 2088
22
Liraglutide Approved Phase 4 204656-20-2 44147092
23
Zinc Approved, Investigational Phase 4 7440-66-6 32051
24
Cefuroxime Approved Phase 4 55268-75-2 5361202 5479529
25
Cefazolin Approved Phase 4 25953-19-9 656510 33255
26
Cefdinir Approved Phase 4 91832-40-5 6915944
27
Sulfamethoxazole Approved Phase 4 723-46-6 5329
28
Clindamycin Approved, Vet_approved Phase 4 18323-44-9 29029
29
Trimethoprim Approved, Vet_approved Phase 4 738-70-5 5578
30
Bromocriptine Approved, Investigational Phase 4 25614-03-3 31101
31
Salmon Calcitonin Approved, Investigational Phase 4 47931-85-1 16129616
32
Quinagolide Approved, Investigational Phase 4 87056-78-8, 97805-50-0 105105
33
Sodium sulfate Approved, Vet_approved Phase 4 7757-82-6
34
Tramadol Approved, Investigational Phase 4 27203-92-5 33741
35
Acetaminophen Approved Phase 4 103-90-2 1983
36
Guaifenesin Approved, Investigational, Vet_approved Phase 4 93-14-1 3516
37
Codeine Approved, Illicit Phase 4 76-57-3 5284371
38
Nitric Oxide Approved Phase 4 10102-43-9 145068
39
Somatostatin Approved, Investigational Phase 4 51110-01-1, 38916-34-6 53481605
40
lanreotide Approved Phase 4 108736-35-2
41
Citric acid Approved, Nutraceutical, Vet_approved Phase 4 77-92-9 311
42
Vitamin C Approved, Nutraceutical Phase 4 50-81-7 5785 54670067
43
Ecabet Investigational Phase 4 33159-27-2, 86408-72-2 65781
44
Calcitonin gene-related peptide Investigational Phase 4 83652-28-2
45
Lactitol Investigational Phase 4 585-86-4, 585-88-6 493591
46 Muscarinic Antagonists Phase 4
47 Cholinergic Agents Phase 4
48 Butylscopolammonium Bromide Phase 4
49 Cholinergic Antagonists Phase 4
50 Bromides Phase 4

Interventional clinical trials:

(show top 50) (show all 1021)
# Name Status NCT ID Phase Drugs
1 Does Hyoscine N-butylbromide Administered During Colonoscopy Increase the Polyp Detection Rate? a Randomized, Single Center, Double Blind, Placebo-controlled Study Unknown status NCT01609855 Phase 4 Hyoscine Butyl Bromide 20mg/2 ml i.v.;Saline 2 ml i.v.
2 Erythromycin Treatment for Readthrough of APC Gene Stop Codon Mutation in Familial Adenomatous Polyposis-protocol is Identical to Study No. 0519-10-TLV- Minors' Adjusted Version Unknown status NCT02354560 Phase 4 Erythromycin
3 Erythromycin as a Novel Therapy Against Familial Adenomatous Polyposis and Sporadic Colorectal Cancer by APC Nonsense Mutation Readthrough. Unknown status NCT02175914 Phase 4 Erythromycin
4 Efficacy and Cost-effectiveness of Colonoscopy vs. Combined Fecal Immunochemical Test-Sigmoidoscopy for the Detection of Advanced Colorectal Neoplasia (eCOLO-FITS): A Randomized Multicenter Trial Unknown status NCT01767870 Phase 4
5 Effects of Ilaprazole 20mg on Ulcer Healing Rate and Prevention of Gastrointestinal Bleeding in the Patients Undergone Endoscopic Submucosal Dissection(ESD) for Gastric Adenoma or Early Gastric Cancer. Unknown status NCT02638584 Phase 4 Ilaprazole;Rabeprazole
6 Premedication Dyclonine Improves Visibility During Bowel Cleansing for Colonoscopy Unknown status NCT03352700 Phase 4 3L PEG;3L PEG+Dyclonine Hydrochloride Mucilage
7 Impact of Reinforced Education by Wechat and Short Message Service on the Quality of Bowel Preparation Unknown status NCT02832869 Phase 4
8 Comparison of the Efficacy and Tolerability Between 3-L and 4-L Polyethylene Glycol in Bowel Preparation Unknown status NCT03356015 Phase 4 4L Polyethylene Glycol;3L Polyethylene Glycol
9 Influence of Synacthen Infusion on the Results of Adrenal Venous Sampling in Patient With Primary Aldosteronism Unknown status NCT02127840 Phase 4 Synacthen infusion during adrenal venous sampling
10 Assessment of the Participation Rate and the Diagnostic Accuracy of a Colorectal Cancer Screening Program: CT Colonography Versus Flexible Sigmoidoscopy. Evaluation of a New Model Based on Telediagnosis Unknown status NCT01739608 Phase 4
11 Effect of Perioperative Glucocorticoid Replacement on Prognosis of Surgical Patients With Sellar Lesions Unknown status NCT02190994 Phase 4 Hydrocortisone;Prednisone
12 Efficacy and Safety of Pasireotide Long Acting Release (LAR) in Combination With Weekly Pegvisomant in Previously Controlled Acromegaly Patients on Combination Treatment of Long-Acting Somatostatin Analogues and Weekly Pegvisomant Unknown status NCT02668172 Phase 4 Pasireotide LAR 60 mg;Pegvisomant
13 Efficacy of an Ecabet Sodium and Proton Pump Inhibitor (PPI) Combination Therapy in the Treatment of Iatrogenic Ulcer After Endoscopic Submucosal Dissection: A Prospective Randomized Controlled Trial Unknown status NCT01308177 Phase 4 Ecabet
14 Does Early Re-administration of Aspirin/Clopidogrel Increase the Risk of Bleeding From Artificial Ulcer After EMR or ESD? Unknown status NCT01621451 Phase 4 aspirin and/or clopidogrel;aspirin and/or clopidogrel
15 Prophylactic Pancreatic Duct Stent Placement After Endoscopic Snare Papillectomy of Duodenal Major Papillary Tumors; Prospective, Randomized, Controlled Study Unknown status NCT01737463 Phase 4
16 Long-term (up to 3 Years) Clinical and Hormonal Outcomes in Acromegalic Patients With Treated Surgery With or Without Long Acting Somatostatin Analogues: Open-labeled, Prospective, Parallel Group Study Unknown status NCT02427295 Phase 4 Sandostatin (Octreotide Acetate)
17 Efficacy of Prucalopride Plus Polyethylene Glycol in Bowel Preparation for Colonoscopy Unknown status NCT02781493 Phase 4 2 mg Prucalopride plus 2 L Polyethylene Glycol regimen;2 mg Placebo plus 2 L Polyethylene Glycol regimen
18 The Therapeutic Effect of Bromocriptin in Patients With Primary Aldosteronism Unknown status NCT00451672 Phase 4 bromocriptine
19 Helicobacter Pylori Eradication Rates of Concomitant Therapy and Tailored Therapy Based on 23S Ribosomal RNA Point Mutations Associated With Clarithromycin Resistance: A Multicenter Prospective Randomized Study Unknown status NCT03130452 Phase 4 Lansoprazole 30mg;Amoxicillin 1.0g Tab;Clarithromycin 500mg;Metronidazole 500 mg
20 Optimal Bowel Preparation Regimen for Patients With With a History of Colorectal Resection Before Colonoscopy Unknown status NCT02761317 Phase 4 standard preparation (2L PEG-ELS);low-volume preparation (10 mg bisacodyl plus 2L PEG-ELS);high-volume preparation (4L PEG-ELS)
21 Clinical Effectiveness of Serum Chromogranin A (CgA) Levels on Diagnostic Relevance, Response After Surgical Resection and Recurrence of Pancreatic Endocrine Tumors (PET) Unknown status NCT02759718 Phase 4
22 Ejaculatory Sparing vs. Non-ejaculatory Sparing GreenLightTM Laser Photoselective Vaporization of the Prostate (PVP): A Randomized Double Blind Sexual and Urodynamic Assessment Unknown status NCT02749604 Phase 4
23 Does Surgical Debulking Of Pituitary Adenomas Improve Responsiveness To Octreotide LAR In The Treatment Of Acromegaly: An Investigator-Initiated Study Completed NCT01371643 Phase 4 Octreotide LAR
24 Comparative Efficacy of Water & Indigo Carmine vs Water or Air Method Completed NCT01607255 Phase 4 Indigo carmine
25 Can Involvement of Endoscopy Nurse Participation Increase Adenoma Detection Rate During Screening Colonoscopy?:A Prospective Multicenter Randomized Trial Completed NCT01124266 Phase 4
26 A SINGLE-ARM OPEN-LABEL INTERNATIONAL MULTI-CENTER STUDY OF THE EFFICACY AND SAFETY OF SUNITINIB MALATE (SU011248, SUTENT (REGISTERED)) IN PATIENTS WITH PROGRESSIVE ADVANCED METASTATIC WELL-DIFFERENTIATED UNRESECTABLE PANCREATIC NEUROENDOCRINE TUMORS Completed NCT01525550 Phase 4 sunitinib
27 The Effect Of Adding High Dose Simethicone To A Standard Polyethylene Glycol Preparation On Adenoma Detection Rate During Screening Colonoscopy: A Randomized Controlled Pilot Trial Completed NCT03119168 Phase 4 Simethicone Solution
28 A Multi-centre, Randomised, Investigator-blinded Study Comparing the Polyp Detection Rate of Two Different Types of Bowel Preparation: a 2-litre Solution (MOVIPREP®) Versus a Hyperosmotic and Stimulant Combined Low Volume Bowel Preparation (Sodium Picosulfate and Magnesium Citrate) Completed NCT01689792 Phase 4 MOVIPREP;CitraFleet
29 Octreotide Efficacy and Safety in First-line Acromegalic Patients Completed NCT00171886 Phase 4 Octreotide
30 Effect of Gum Chewing on Bowel Cleansing Before Colonoscopy: A Prospective Randomized Study Completed NCT02507037 Phase 4 polyethylene glycol
31 A Multicenter, Single Arm, Proof of Concept Study to Investigate the Efficacy of an 8 Month Combination Therapy of Octreotide and Cabergoline in Acromegalic Patients Only Partially Responsive to Somatostatin Analog Monotherapy Completed NCT00376064 Phase 4 Octreotide acetate and cabergoline/Octrotide and Somavert
32 Role of Glucagon in Outpatient Colonoscopy? A Prospective Double-Blind Randomized Controlled Trial Completed NCT02078726 Phase 4 Glucagon;Placebo
33 Green Light Laser (XPS) Photoselective Vaporization of the Prostate (PVP) Versus Bipolar Transurethral Vaporization (B.TUVP) of the Prostate for Treatment of Small to Moderate Sized Benign Prostate Hyperplasia: A Randomized Study Completed NCT02283684 Phase 4
34 Preoperative Octreotide Treatment of Patients With Growth Hormone Producing Pituitary Adenomas Completed NCT00521300 Phase 4 Octreotide
35 Adipokine Profile in Patients With Cushing's Disease on Pasireotide Treatment: Correlation With Disease Activity, Insulin Sensitivity and Secretion Parameters Completed NCT03080181 Phase 4 Pasireotide 0.6 MG/ML
36 A Prospective Randomised Controlled Trial Comparing Cap-Assisted Colonoscopy Versus Standard Colonoscopy Completed NCT00930462 Phase 4
37 Evaluation of the Effects of Monopolar Transurethral Resection Versus Bipolar Transurethral Resection and Holmium Laser Enucleation of the Prostate on Urinary and Sexual Function; a Prospective Comparative Study. Completed NCT01810068 Phase 4
38 Efficacy of a Calcimimetic (Cinacalcet) in the Long Term Control of Patients With Primary Hyperparathyroidism Completed NCT02417389 Phase 4 cinacalcet;Alendronate
39 Tailored Bowel Preparation According to Bristol Stool Form Scale: a Prospective, Randomized, Controlled, Investigator-blinded, Multicenter Study Completed NCT02415569 Phase 4 Standard Bowel Prep (2L PEG-ELP);2L PEG-ELP and 10mg bisacodyl;Standard Bowel Prep (2L PEG-ELP)
40 Randomized Study Comparing Holmium Laser Enucleation of the Prostate (HOLEP) Versus Greenlight (XPS) Laser Photoselective Vapo-Enucleation of Prostate(PVEP) in the Management of Infravesical Obstruction Secondary to BPH Completed NCT01494337 Phase 4
41 Effects of Preoperative Administration of Oral Rabeprazole on the Prevention of Ulcer Bleeding Following Endoscopic Mucosal Resection(EMR): Prospective, Randomized, Placebo-controlled, Comparative Study Completed NCT00844675 Phase 4 rabeprazole;placebo
42 A Multi-center, Randomized, Open-label, Phase IV Study to Investigate the Management of Pasireotide-induced Hyperglycemia With Incretin Based Therapy or Insulin in Adult Patients With Cushing's Disease or Acromegaly Completed NCT02060383 Phase 4 Pasireotide s.c.;Sitagliptin;Liraglutide;Insulin;Pasireotide LAR;Metformin
43 A Randomized, Double-blind, Comparative, Effectiveness and Safety Study of Eleview vs. Hetastarch in Subjects Undergoing Endoscopic Mucosal Resection (EMR) of Colonic Lesions Equal to or Larger Than 11mm Completed NCT03350217 Phase 4 Eleview;Hetastarch
44 EFFICACY EVALUATION OF PRUNUS DOMESTICA EXTRACT ON BENIGN PROSTATE HYPERPLASIA (BPH): An Add on Study Completed NCT02702947 Phase 4
45 Prospective, Multicenter Study for the Evaluation of Safety and Performance of the Interscope EndoRotor Endoscopic Mucosal Resection System for the Removal of Alimentary Tract Mucosa in the Colon Recruiting NCT04203667 Phase 4
46 A Multicenter, Randomized, Placebo-Controlled, Double-Blind Study Evaluating the Impact of Prophylactic Oral Antibiotics on Sinonasal Outcomes Following Endoscopic Transsphenoidal Surgery for Pituitary Lesions Recruiting NCT03014687 Phase 4 Placebo;Oral Antibiotics cefdinir or trimethoprim/sulfamethoxazole
47 Improving the Sensitivity of Sestamibi SPECT-CT Parathyroid Scan With Calcitonin Pre-treatment for Primary Hyperparathyroidism Recruiting NCT03935984 Phase 4 Calcitonin
48 PRolaCT - Three Multicenter Prolactinoma Randomized Clinical Trials Recruiting NCT04107480 Phase 4 Dopamine Agonists
49 A Multicentre Randomized Parallel Group Phase IV Study Comparing the Bowel Cleansing Efficacy, Safety and Tolerability of PLENVU® Versus SELG-ESSE® Using a 2-Day Split Dosing Regimen. Recruiting NCT03742232 Phase 4 PEG3350;Macrogol 4000
50 Minimizing Narcotic Analgesics After Thyroid or Parathyroid Surgery Recruiting NCT03469310 Phase 4 Acetaminophen 500Mg Cap;Tylenol #3 Oral Tablet;Tramadol

Search NIH Clinical Center for Adenoma

Inferred drug relations via UMLS 71 / NDF-RT 50 :


Octreotide
Octreotide Acetate
Sources

Genetic Tests for Adenoma

About this section
Sources

Anatomical Context for Adenoma

About this section

MalaCards organs/tissues related to Adenoma:

40
Pituitary, Thyroid, Colon, Prostate, Salivary Gland, Liver, Testes
Sources

Publications for Adenoma

About this section

Articles related to Adenoma:

(show top 50) (show all 52884)
# Title Authors PMID Year
1
Differentiation of tubular and villous adenomas based on Wnt pathway-related gene expression profiles. 54 61
20514431 2010
2
Biallelic MYH germline mutations as cause of Muir-Torre syndrome. 54 61
19998059 2010
3
Fish fatty acids alter markers of apoptosis in colorectal adenoma and adenocarcinoma cell lines but fish consumption has no impact on apoptosis-induction ex vivo. 54 61
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Immunohistochemical detection of somatostatin receptor subtype 5 (SSTR-5) in cushing adenoma. 54 61
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ACB-PCR quantification of K-RAS codon 12 GAT and GTT mutant fraction in colon tumor and non-tumor tissue. 54 61
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Effects of calcium and vitamin D on MLH1 and MSH2 expression in rectal mucosa of sporadic colorectal adenoma patients. 54 61
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Clear cell adenocarcinoma of the bladder and urethra: cases diffusely mimicking nephrogenic adenoma. 54 61
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Increased expression of HMGA1 correlates with tumour invasiveness and proliferation in human pituitary adenomas. 54 61
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Pituitary adenomas that show a faint GH-immunoreactivity but lack fibrous body: Pit-1 adenoma with endocrinologically low activity. 54 61
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High expression of Toll-like receptor 4/myeloid differentiation factor 88 signals correlates with poor prognosis in colorectal cancer. 54 61
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Frequent promoter hypermethylation of the APC and RASSF1A tumour suppressors in parathyroid tumours. 54 61
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Identification of histologically distinct conventional adenomas that arise predominately in patients with sessile serrated adenomas. 54 61
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Dietary, lifestyle and clinicopathological factors associated with BRAF and K-ras mutations arising in distinct subsets of colorectal cancers in the EPIC Norfolk study. 54 61
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Complete deletion of Apc results in severe polyposis in mice. 54 61
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Reversal of gene expression changes in the colorectal normal-adenoma pathway by NS398 selective COX2 inhibitor. 54 61
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The tobacco-specific carcinogen NNK induces DNA methyltransferase 1 accumulation and tumor suppressor gene hypermethylation in mice and lung cancer patients. 54 61
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Effect of everolimus on cell viability in nonfunctioning pituitary adenomas. 54 61
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Elevation of growth hormone secretagogue receptor type 1a mRNA expression in human growth hormone-secreting pituitary adenoma harboring G protein alpha subunit mutation. 54 61
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Molecular genetics of hepatocellular neoplasia. 54 61
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ACTH-independent Cushing's syndrome with bilateral micronodular adrenal hyperplasia and ectopic adrenocortical adenoma. 54 61
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Immunohistochemistry of COUP-TFI: an adjuvant diagnostic tool for the identification of corticotroph microadenomas. 54 61
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Identifying mutations for MYH-associated polyposis. 54 61
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Gradual loss of functional gap junction within progression of colorectal cancer -- a shift from membranous CX32 and CX43 expression to cytoplasmic pattern during colorectal carcinogenesis. 54 61
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Synaptophysin immunoreactivity in adrenocortical adenomas: a correlation between synaptophysin and CYP17A1 expression. 54 61
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An immunohistochemical study of colon adenomas and carcinomas: E-cadherin, Syndecan-1, Ets-1. 54 61
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A case of Peutz-Jeghers syndrome with breast cancer, bilateral sex cord tumor with annular tubules, and adenoma malignum caused by STK11 gene mutation. 54 61
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Differential effects of reactive nitrogen species on DNA base excision repair initiated by the alkyladenine DNA glycosylase. 54 61
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Clear cell change in colonic polyps. 54 61
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Beta-catenin nuclear labeling is a common feature of sessile serrated adenomas and correlates with early neoplastic progression after BRAF activation. 54 61
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Cyclooxygenase-2 expression is related to the epithelial-to-mesenchymal transition in human colon cancers. 54 61
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Colorectal mucosal expression of MSH2 as a potential biomarker of risk for colorectal neoplasms. 54 61
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Expression of CD44 in canine mammary tumours. 54 61
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A Wnt kinase network alters nuclear localization of TCF-1 in colon cancer. 54 61
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Dissociation of EphB2 signaling pathways mediating progenitor cell proliferation and tumor suppression. 54 61
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