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MCID: ADN009
MIFTS: 54

Adenosquamous Carcinoma

Categories: Cancer diseases, Endocrine diseases
Genes Tissues Related diseases Publications Pathways Drugs
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Aliases & Classifications for Adenosquamous Carcinoma

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MalaCards integrated aliases for Adenosquamous Carcinoma:

Name: Adenosquamous Carcinoma 12 15 17 74
Mixed Adenocarcinoma and Squamous Carcinoma 12
Adenosquamous Cell Carcinoma 12
Carcinoma, Adenosquamous 45
Carcinoma Adenosquamous 56

Classifications:

MalaCards categories:
Global: Cancer diseases
Anatomical: Endocrine diseases
See all MalaCards categories (disease lists)


External Ids:

Disease Ontology 12 DOID:4830
MeSH 45 D018196
NCIt 51 C3727
SNOMED-CT 69 59367005
UMLS 74 C0206623
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Summaries for Adenosquamous Carcinoma

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Disease Ontology : 12 A squamous cell carcinoma that contains squamous cells and gland-like cells.

MalaCards based summary : Adenosquamous Carcinoma, also known as mixed adenocarcinoma and squamous carcinoma, is related to pancreatic adenosquamous carcinoma and adenosquamous lung carcinoma. An important gene associated with Adenosquamous Carcinoma is EGFR (Epidermal Growth Factor Receptor), and among its related pathways/superpathways are Gastric cancer and Downstream signaling events of B Cell Receptor (BCR). The drugs Cisplatin and Epoetin alfa have been mentioned in the context of this disorder. Affiliated tissues include cervix, lung and pancreas, and related phenotypes are Decreased viability and Decreased viability

Wikipedia : 77 Adenosquamous carcinoma is a type of cancer that contains two types of cells: squamous cells (thin, flat... more...

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Related Diseases for Adenosquamous Carcinoma

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Diseases related to Adenosquamous Carcinoma via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50) (show all 283)
# Related Disease Score Top Affiliating Genes
1 pancreatic adenosquamous carcinoma 33.8 KRAS PTHLH
2 adenosquamous lung carcinoma 31.8 EGFR KRAS PIK3CA
3 adenoid squamous cell carcinoma 30.6 KRT7 KRT8
4 syringocystadenoma papilliferum 30.5 KRAS MUC1
5 small cell carcinoma 30.3 EGFR KRT7 TP53
6 in situ carcinoma 30.3 EGFR KRT5 TP53
7 adenocarcinoma 30.3 EGFR KRAS MUC1 MUC4 PIK3CA TP53
8 gastrointestinal stromal tumor 30.2 EGFR KRAS TP53
9 lynch syndrome 30.2 EGFR KRAS TP53
10 villous adenoma 30.1 KRAS KRT8 MUC1
11 cystadenoma 30.0 KRT7 MUC1 MUC4
12 mucoepidermoid carcinoma 30.0 EGFR KRT7 MUC1 MUC4 TP63
13 dermoid cyst 30.0 KRT7 MUC1 TP63
14 mucinous adenocarcinoma 30.0 EGFR KRAS KRT7 MUC1
15 gastric squamous cell carcinoma 29.9 KRT5 KRT7 SERPINA3
16 cervical cancer 29.9 KRT5 PIK3CA TP53 TP63
17 lymphoepithelioma-like carcinoma 29.9 KRT5 KRT7 KRT8 MUC1
18 spindle cell carcinoma 29.8 KRT5 KRT7 MUC1 TP63
19 necrotizing sialometaplasia 29.7 KRT5 KRT7 TP53 TP63
20 hidradenoma 29.7 KRT7 MUC1 PIK3CA
21 small cell cancer of the lung 29.7 EGFR KRT7 PIK3CA TP53
22 cystadenocarcinoma 29.7 KRT7 MUC1 PIK3CA TP53
23 squamous cell carcinoma 29.6 EGFR MUC1 PIK3CA PTHLH TP53 TP63
24 carcinosarcoma 29.4 KRAS KRT7 MUC1 PIK3CA TP53
25 papilloma 29.4 KRT5 KRT7 KRT8 TP53 TP63
26 gallbladder cancer 29.2 EGFR KRAS MUC1 PIK3CA TP53
27 endometrial cancer 28.7 AR EGFR KRAS KRT7 PIK3CA TP53
28 lung cancer 28.5 EGFR KRAS KRT7 MUC4 PIK3CA PTHLH
29 breast cancer 27.6 AR EGFR KRAS KRT5 KRT8 MUC1
30 glassy cell variant cervical adenosquamous carcinoma 12.4
31 endometrial adenosquamous carcinoma 12.4
32 gastric adenosquamous carcinoma 12.4
33 cervical adenosquamous carcinoma 12.4
34 esophageal adenosquamous carcinoma 12.3
35 thymus adenosquamous carcinoma 12.3
36 bartholin's gland adenosquamous carcinoma 12.2
37 ampulla of vater adenosquamous carcinoma 12.2
38 adenosquamous colon carcinoma 11.7
39 adenosquamous prostate carcinoma 11.6
40 adenosquamous gallbladder carcinoma 11.4
41 adenosquamous breast carcinoma 11.1
42 adenosquamous bile duct carcinoma 11.1
43 duodenum adenocarcinoma 10.5 KRAS KRT7
44 hepatoid adenocarcinoma 10.5 EGFR MUC1
45 anal canal adenocarcinoma 10.5 KRAS KRT7
46 appendix disease 10.5 KRAS KRT7
47 nodular hidradenoma 10.5 KRT7 MUC1
48 parachordoma 10.4 KRT7 MUC1
49 mucinous ovarian cystadenoma 10.4 KRT7 MUC1
50 bile duct cystadenocarcinoma 10.4 KRT7 MUC1

Graphical network of the top 20 diseases related to Adenosquamous Carcinoma:



Diseases related to Adenosquamous Carcinoma
Sources

Symptoms & Phenotypes for Adenosquamous Carcinoma

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GenomeRNAi Phenotypes related to Adenosquamous Carcinoma according to GeneCards Suite gene sharing:

27
# Description GenomeRNAi Source Accession Score Top Affiliating Genes
1 Decreased viability GR00055-A-2 9.58 EGFR KRAS MUC1 PIK3CA
2 Decreased viability GR00106-A-0 9.58 KRAS
3 Decreased viability GR00221-A-1 9.58 EGFR KRAS PIK3CA
4 Decreased viability GR00221-A-2 9.58 KRAS PIK3CA
5 Decreased viability GR00221-A-4 9.58 EGFR PIK3CA
6 Decreased viability GR00301-A 9.58 KRAS
7 Decreased viability GR00381-A-1 9.58 KRAS
8 Decreased viability GR00402-S-2 9.58 EGFR KRAS MUC1 PIK3CA
9 Decreased cell migration GR00055-A-1 9.26 EGFR KRAS MUC1 PIK3CA

MGI Mouse Phenotypes related to Adenosquamous Carcinoma:

47 (show all 15)
# Description MGI Source Accession Score Top Affiliating Genes
1 cardiovascular system MP:0005385 10.15 AR EGFR KRAS KRT8 PIK3CA PTHLH
2 digestive/alimentary MP:0005381 10.13 AR EGFR KRAS KRT5 KRT8 PTHLH
3 growth/size/body region MP:0005378 10.13 AR EGFR KRAS KRT5 KRT8 PIK3CA
4 craniofacial MP:0005382 10.08 AR EGFR KRAS KRT5 PTHLH TP53
5 integument MP:0010771 10.06 AR EGFR KRAS KRT5 PIK3CA PTHLH
6 embryo MP:0005380 10.05 AR EGFR KRAS KRT8 PIK3CA TP53
7 endocrine/exocrine gland MP:0005379 10.04 AR EGFR KRAS PIK3CA PTHLH TP53
8 limbs/digits/tail MP:0005371 9.98 AR EGFR KRAS KRT5 PTHLH TP53
9 liver/biliary system MP:0005370 9.88 AR EGFR KRAS KRT8 PTHLH TP53
10 neoplasm MP:0002006 9.87 AR EGFR KRAS PIK3CA PTHLH TP53
11 muscle MP:0005369 9.85 AR EGFR KRAS PIK3CA TP53 TP63
12 no phenotypic analysis MP:0003012 9.73 EGFR KRAS KRT5 PIK3CA TP53 TP63
13 renal/urinary system MP:0005367 9.7 AR EGFR KRAS KRT7 PTHLH TP53
14 reproductive system MP:0005389 9.56 AR EGFR KRAS KRT8 PIK3CA PTHLH
15 skeleton MP:0005390 9.17 AR EGFR KRAS PIK3CA PTHLH TP53
Sources

Drugs & Therapeutics for Adenosquamous Carcinoma

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Drugs for Adenosquamous Carcinoma (from DrugBank, HMDB, Dgidb, PharmGKB, IUPHAR, NovoSeek, BitterDB):

(show top 50) (show all 137)
# Name Status Phase Clinical Trials Cas Number PubChem Id
1
Cisplatin Approved Phase 4,Phase 3,Phase 2,Phase 1 15663-27-1 441203 84093 2767
2 Epoetin alfa Phase 4,Phase 3 113427-24-0
3 Hematinics Phase 4,Phase 3
4
Paclitaxel Approved, Vet_approved Phase 3,Phase 2,Phase 1 33069-62-4 36314
5
Carboplatin Approved Phase 3,Phase 2,Phase 1 41575-94-4 38904 10339178 498142
6
Topotecan Approved, Investigational Phase 3,Phase 2,Phase 1 123948-87-8, 119413-54-6 60700
7
Bevacizumab Approved, Investigational Phase 3,Phase 2,Phase 1 216974-75-3
8
Vinorelbine Approved, Investigational Phase 3 71486-22-1 60780 44424639
9
Gemcitabine Approved Phase 3,Phase 2,Phase 1 95058-81-4 60750
10
Doxorubicin Approved, Investigational Phase 3,Phase 1 23214-92-8 31703
11
Lenograstim Approved, Investigational Phase 3,Phase 2,Phase 1 135968-09-1
12
Vinblastine Approved Phase 3 865-21-4 13342 241903
13
leucovorin Approved Phase 3,Phase 2 58-05-9 6006 143
14
Methotrexate Approved Phase 3 1959-05-2, 59-05-2 126941
15
Ifosfamide Approved Phase 3 3778-73-2 3690
16
Fluorouracil Approved Phase 3,Phase 1,Phase 2 51-21-8 3385
17
Bleomycin Approved, Investigational Phase 3 11056-06-7 5360373
18
Vindesine Approved, Investigational Phase 3 59917-39-4, 53643-48-4 40839
19
Mecasermin Approved, Investigational Phase 3 68562-41-4
20
Folic Acid Approved, Nutraceutical, Vet_approved Phase 3,Phase 2 59-30-3 6037
21
Doxil Approved June 1999 Phase 3,Phase 1 31703
22
Tirapazamine Investigational Phase 3,Phase 2,Phase 1 27314-97-2
23 Albumin-Bound Paclitaxel Phase 3,Phase 2,Phase 1
24 Antimitotic Agents Phase 3,Phase 2,Phase 1
25 Antineoplastic Agents, Phytogenic Phase 3,Phase 2,Phase 1
26 Antineoplastic Agents, Immunological Phase 3,Phase 2,Phase 1
27 Insulin, Globin Zinc Phase 3
28 insulin Phase 3
29 topoisomerase I inhibitors Phase 3,Phase 2,Phase 1
30 Antibodies Phase 3,Phase 2,Phase 1
31 Immunologic Factors Phase 3,Phase 2,Phase 1
32 Topoisomerase Inhibitors Phase 3,Phase 2,Phase 1
33 Endothelial Growth Factors Phase 3,Phase 2,Phase 1
34 Mitogens Phase 3,Phase 2,Phase 1
35 Angiogenesis Modulating Agents Phase 3,Phase 2,Phase 1
36 Angiogenesis Inhibitors Phase 3,Phase 2,Phase 1
37 Immunoglobulins Phase 3,Phase 2,Phase 1
38 Antibodies, Monoclonal Phase 3,Phase 2,Phase 1
39 Immunoglobulin G Phase 3,Phase 2,Phase 1
40 Immunosuppressive Agents Phase 3,Phase 2,Phase 1
41 Antimetabolites Phase 3,Phase 2,Phase 1
42 Anti-Infective Agents Phase 3,Phase 2,Phase 1
43 Antiviral Agents Phase 3,Phase 2,Phase 1
44 Antimetabolites, Antineoplastic Phase 3,Phase 2,Phase 1
45 Antibiotics, Antitubercular Phase 3,Phase 2,Phase 1
46 Anti-Bacterial Agents Phase 3,Phase 2,Phase 1
47 Adjuvants, Immunologic Phase 3,Phase 2,Phase 1
48 Alkylating Agents Phase 3,Phase 2,Phase 1
49 Nucleic Acid Synthesis Inhibitors Phase 3,Phase 2
50 Folate Phase 3,Phase 2

Interventional clinical trials:

(show top 50) (show all 107)
# Name Status NCT ID Phase Drugs
1 Epoetin Beta in Treating Anemia in Patients With Cervical Cancer Completed NCT00046969 Phase 4 cisplatin
2 Paclitaxel and Cisplatin or Topotecan With or Without Bevacizumab in Treating Patients With Stage IVB, Recurrent, or Persistent Cervical Cancer Completed NCT00803062 Phase 3 Cisplatin;Paclitaxel;Topotecan Hydrochloride
3 Comparison of Four Combination Chemotherapy Regimens Using Cisplatin in Treating Patients With Stage IVB, Recurrent, or Persistent Cancer of the Cervix Completed NCT00064077 Phase 3 Cisplatin;Gemcitabine Hydrochloride;Paclitaxel;Topotecan Hydrochloride;Vinorelbine Tartrate
4 Comparison of Two Combination Chemotherapy Regimens Plus Radiation Therapy in Treating Patients With Stage III or Stage IV Endometrial Cancer Completed NCT00006011 Phase 3 Doxorubicin Hydrochloride;Cisplatin;Paclitaxel
5 Radiation Therapy and Cisplatin With or Without Epoetin Alfa in Treating Patients With Cervical Cancer and Anemia Completed NCT00017004 Phase 3 Cisplatin
6 Radiation Therapy With or Without Chemotherapy After Surgery in Treating Patients With Stage IB or Stage IIA Cervical Cancer Completed NCT00003209 Phase 3 cisplatin;fluorouracil;ifosfamide;methotrexate;mitomycin C;vinblastine sulfate;vindesine
7 Comparison of Three Chemotherapy Regimens in Treating Patients With Stage IVB, Recurrent, or Persistent Cervical Cancer Completed NCT00003945 Phase 3 cisplatin;topotecan hydrochloride
8 Radiation Therapy or Observation Only in Treating Patients With Endometrial Cancer Who Have Undergone Surgery Completed NCT00002807 Phase 3
9 Radiation Therapy With or Without Cisplatin or Fluorouracil in Treating Patients With Cancer of the Cervix Completed NCT00003078 Phase 3 cisplatin;fluorouracil
10 Radiation Therapy Compared With Combination Chemotherapy in Treating Patients With Advanced Endometrial Cancer Completed NCT00002493 Phase 3 cisplatin;doxorubicin hydrochloride
11 Comparison of Radiation Therapy With or Without Combination Chemotherapy Following Surgery in Treating Patients With Stage I or Stage II Endometrial Cancer Completed NCT00006027 Phase 3 cisplatin;paclitaxel
12 Radiation Therapy With or Without Chemotherapy in Patients With Stage I-IIA Cervical Cancer Who Previously Underwent Surgery Recruiting NCT01101451 Phase 3 Cisplatin
13 Chemotherapy and Pelvic Radiation Therapy With or Without Additional Chemotherapy in Treating Patients With High-Risk Early-Stage Cervical Cancer After Radical Hysterectomy Recruiting NCT00980954 Phase 3 carboplatin;cisplatin;paclitaxel
14 Extraperitoneal Para-aortic Lymph Node Dissection (EPLND) for Cervix Active, not recruiting NCT01365156 Phase 3
15 Cisplatin and Radiation Therapy With or Without Carboplatin and Paclitaxel in Patients With Locally Advanced Cervical Cancer Active, not recruiting NCT01414608 Phase 3 Carboplatin;Cisplatin;Paclitaxel
16 Chemotherapy Followed By Surgery Vs Radiotherapy Plus Chemotherapy in Patients With Stage IB or II Cervical Cancer Active, not recruiting NCT00039338 Phase 3 cisplatin
17 Carboplatin And Paclitaxel With Or Without CP-751, 871 (An IGF-1R Inhibitor) For Advanced NSCLC Of Squamous, Large Cell And Adenosquamous Carcinoma Histology Terminated NCT00596830 Phase 3 CP-751,871 (Figitumumab);Carboplatin;Paclitaxel;Carboplatin;Paclitaxel
18 Evaluation of Hysterectomy After Chemoradiation Therapy for Stage IB2/II Cervical Cancer Terminated NCT01363466 Phase 3
19 Chemotherapy and Radiation Therapy With or Without Surgery in Treating Patients With Stage I Cancer of the Cervix Terminated NCT00054067 Phase 3 cisplatin
20 Cisplatin and Radiation Therapy With or Without Tirapazamine in Treating Patients With Cervical Cancer Terminated NCT00262821 Phase 3 cisplatin;tirapazamine
21 Cisplatin and Radiation Therapy With or Without Hyperthermia Therapy in Treating Patients With Cervical Cancer Terminated NCT00085631 Phase 3 cisplatin
22 Cisplatin Combined With Radiation Therapy and Hyperthermia in Treating Patients With Stage II, Stage III, or Stage IV Cervical Cancer Unknown status NCT00008112 Phase 2 cisplatin
23 Panitumumab, Cisplatin, and Pelvic Radiation Therapy in Treating Patients With Stage IB, Stage II, or Stage III Cervical Cancer Unknown status NCT01158248 Phase 2 cisplatin
24 Paclitaxel and Carboplatin Followed by Cisplatin and Radiation Therapy in Treating Patients With Stage IB, Stage II, Stage III, or Stage IVA Cervical Cancer Unknown status NCT00462397 Phase 2 carboplatin;cisplatin;paclitaxel
25 Bryostatin-1 Plus Cisplatin in Treating Patients With Recurrent or Advanced Cancer of the Cervix Completed NCT00005965 Phase 2 bryostatin 1;cisplatin
26 Capecitabine in Treating Patients With Persistent or Recurrent Cervical Cancer Completed NCT00039442 Phase 2 Capecitabine
27 Selumetinib in Treating Patients With Recurrent or Persistent Endometrial Cancer Completed NCT01011933 Phase 2 Selumetinib
28 Gemcitabine in Treating Patients With Recurrent or Persistent Endometrial Cancer Completed NCT00820898 Phase 2 Gemcitabine Hydrochloride
29 Ixabepilone to Treat Cervical Cancer Completed NCT00924066 Phase 2 Ixempra (Ixabepilone (BMS-247550) )
30 Brivanib Alaninate in Treating Patients With Persistent or Recurrent Cervical Cancer Completed NCT01267253 Phase 2 Brivanib Alaninate
31 Akt Inhibitor MK2206 in Treating Patients With Recurrent or Advanced Endometrial Cancer Completed NCT01307631 Phase 2 Akt Inhibitor MK2206
32 Cediranib Maleate in Treating Patients With Recurrent or Persistent Endometrial Cancer Completed NCT01132820 Phase 2 Cediranib Maleate
33 ABI-007 in Treating Patients With Persistent or Recurrent Cervical Cancer Completed NCT00309959 Phase 2 Paclitaxel Albumin-Stabilized Nanoparticle Formulation
34 Pelvic Exenteration in Treating Patients With Recurrent Cervical Cancer Completed NCT00217633 Phase 2
35 Sunitinib Malate in Treating Patients With Uterine Cervical Cancer That is Stage IVB, Recurrent, or Cannot Be Removed By Surgery Completed NCT00389974 Phase 2 sunitinib malate
36 Oxaliplatin and Paclitaxel in Treating Patients With Locally Recurrent or Metastatic Cervical Cancer Completed NCT00057863 Phase 2 Paclitaxel;Oxaliplatin
37 S9717 Tirapazamine Plus Cisplatin in Treating Patients With Metastatic, Recurrent, or Refractory Cervical Cancer Completed NCT00003369 Phase 2 cisplatin;tirapazamine
38 Letrozole in Treating Women With Recurrent or Metastatic Endometrial Cancer Completed NCT00004251 Phase 2 letrozole
39 Erlotinib in Treating Patients With Locally Advanced and/or Metastatic Endometrial Cancer Completed NCT00030485 Phase 2 erlotinib hydrochloride
40 Veliparib, Topotecan Hydrochloride, and Filgrastim or Pegfilgrastim in Treating Patients With Persistent or Recurrent Cervical Cancer Completed NCT01266447 Phase 2 Topotecan Hydrochloride;Veliparib
41 Temsirolimus in Treating Patients With Cervical Cancer That Is Recurrent, Locally Advanced, Metastatic, or Cannot Be Removed By Surgery Completed NCT01026792 Phase 2 Temsirolimus
42 Trebananib in Treating Patients With Persistent or Recurrent Endometrial Cancer Completed NCT01210222 Phase 2
43 Intensity-Modulated Radiation Therapy, Cisplatin, and Bevacizumab Followed by Carboplatin and Paclitaxel in Treating Patients Who Have Undergone Surgery for Endometrial Cancer Completed NCT01005329 Phase 2 Carboplatin;Cisplatin;Paclitaxel
44 Bevacizumab, Radiation Therapy, and Cisplatin in Treating Patients With Previously Untreated Locally Advanced Cervical Cancer Completed NCT00369122 Phase 2 Cisplatin
45 Medroxyprogesterone in Treating Patients With Endometrioid Adenocarcinoma of the Uterine Corpus Completed NCT00064025 Phase 2 Medroxyprogesterone
46 Thalidomide in Treating Patients With Recurrent or Persistent Endometrial Cancer Completed NCT00025467 Phase 2 thalidomide
47 S9720 Combination Chemotherapy in Treating Patients With Metastatic, Recurrent, or Refractory Endometrial Cancer Completed NCT00003127 Phase 2 amifostine trihydrate;carboplatin;paclitaxel
48 Irofulven in Treating Patients With Stage IVB or Recurrent Cervical Cancer Completed NCT00005070 Phase 2 irofulven
49 Interleukin-12 in Treating Patients With Advanced or Recurrent Cancer of the Cervix Completed NCT00003017 Phase 2
50 Surgery and Vaccine Therapy in Treating Patients With Early Cervical Cancer Completed NCT00002916 Phase 2

Search NIH Clinical Center for Adenosquamous Carcinoma

Cochrane evidence based reviews: carcinoma, adenosquamous

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Genetic Tests for Adenosquamous Carcinoma

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Anatomical Context for Adenosquamous Carcinoma

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MalaCards organs/tissues related to Adenosquamous Carcinoma:

42
Cervix, Lung, Pancreas, Lymph Node, Breast, Colon, Liver
Sources

Publications for Adenosquamous Carcinoma

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Articles related to Adenosquamous Carcinoma:

(show top 50) (show all 563)
# Title Authors Year
1
Identification of Adenosquamous Carcinoma as a Rare Aggressive HER2-negative Subgroup of Esophageal/Gastroesophageal Junction Adenocarcinoma. ( 30516569 )
2019
2
Concomitant adenosquamous carcinoma and cystadenocarcinoma of the extrahepatic bile duct: A case report. ( 30705898 )
2019
3
MGL Ligand Expression Is Correlated to Lower Survival and Distant Metastasis in Cervical Squamous Cell and Adenosquamous Carcinoma. ( 30761272 )
2019
4
Gastric squamous cell carcinoma and gastric adenosquamous carcinoma, clinical features and outcomes of rare clinical entities: a National Cancer Database (NCDB) analysis. ( 30788163 )
2019
5
Adenosquamous carcinoma of the uterine cervix displaying tumor-associated tissue eosinophilia. ( 30800306 )
2019
6
Transformation of epidermal growth factor receptor T790M mutation-positive adenosquamous carcinoma of the lung to small cell carcinoma and large-cell neuroendocrine carcinoma following osimertinib therapy: an autopsy case report. ( 30828454 )
2019
7
A Rare Case of Adenosquamous Carcinoma Arising in a Background of IgG4-Related Lung Disease: A case report. ( 30853707 )
2019
8
Comparative outcomes of adenosquamous carcinoma of the pancreas: An analysis of the National Cancer Database. ( 29878370 )
2018
9
A retroperitoneal mass confirmed as a pancreatic adenosquamous carcinoma by endoscopic ultrasound-guided fine-needle aspiration. ( 29069702 )
2018
10
Heterogeneity of PD-L1 Expression Among the Different Histological Components and Metastatic Lymph Nodes in Patients With Resected Lung Adenosquamous Carcinoma. ( 29609906 )
2018
11
A Rare Case of Penile Metastases as a Harbinger of Primary Pulmonary Adenosquamous Carcinoma. ( 29785317 )
2018
12
High rate of PIK3CA mutations but no TP53 mutations in low-grade adenosquamous carcinoma of the breast. ( 29537649 )
2018
13
Clinicopathological characteristics and survival outcomes in adenosquamous carcinoma of the lung: a population-based study from the SEER database. ( 29487721 )
2018
14
Clinical characteristics and prognosis of patients with lung adenosquamous carcinoma after surgical resection: results from two institutes. ( 29850145 )
2018
15
Adenosquamous Carcinoma in the Midline Dorsum of the Tongue: A Rare Case Report. ( 29806990 )
2018
16
Pancreatic adenosquamous carcinoma masquerading as a locally invading splenic abscess. ( 29740918 )
2018
17
Long-term survival with extended lateral lymphadenectomy for lateral lymph node recurrence after laparoscopic abdominoperineal resection for rectal adenosquamous carcinoma: a case report. ( 29633041 )
2018
18
Adenosquamous carcinoma of the bile duct: a population-based study. ( 29563834 )
2018
19
Colonic adenosquamous carcinoma and mucinous adenocarcinoma with microsatellite instability. ( 30173239 )
2018
20
Targeted therapy and immunotherapy for platinum-refractory advanced ovarian adenosquamous carcinoma: a case report. ( 29983579 )
2018
21
Adenosquamous Carcinoma of the Esophagus: A Literature Review. ( 29984200 )
2018
22
Adenosquamous Carcinoma of the Ampulla of Vater: A Rare Cause of Obstructive Jaundice. ( 29998166 )
2018
23
Uncommon Types of Lung Carcinoma With Mixed Histology: Sarcomatoid Carcinoma, Adenosquamous Carcinoma, and Mucoepidermoid Carcinoma. ( 30040455 )
2018
24
Expression of phosphatase and tensin homolog and programmed cell death ligand 1 in adenosquamous carcinoma of the lung. ( 30100056 )
2018
25
Adenosquamous carcinoma of the right colon: A case report and review of the literature. ( 30103094 )
2018
26
Surgical significance and efficacy of epidermal growth factor receptor tyrosine kinase inhibitors in patients with primary lung adenosquamous carcinoma. ( 30122989 )
2018
27
"Pancreatic Mucoepidermoid Carcinoma" Is not a Pancreatic Counterpart of CRTC1/3-MAML2 Fusion Gene-related Mucoepidermoid Carcinoma of the Salivary Gland, and May More Appropriately be Termed Pancreatic Adenosquamous Carcinoma With Mucoepidermoid Carcinoma-like Features. ( 30138216 )
2018
28
Adenosquamous carcinoma of the lung. ( 30147334 )
2018
29
Adenosquamous carcinoma arising in a duplication cyst of the gallbladder. ( 30221164 )
2018
30
Cervical adenosquamous carcinoma: detailed analysis of morphology, immunohistochemical profile, and clinical outcomes in 59 cases. ( 30258209 )
2018
31
Survival analysis for lung adenosquamous carcinoma patients with brain metastasis. ( 30405840 )
2018
32
Research progress of the clinicopathologic features of lung adenosquamous carcinoma. ( 30410358 )
2018
33
Adenosquamous carcinoma of the papilla of Vater: A phenotypic heterogeneity characterized by a common molecular landscape. ( 30417956 )
2018
34
Low-grade Adenosquamous Carcinoma of the Breast: A Case Report. ( 30449342 )
2018
35
Adenosquamous Carcinoma of the Anus: An Uncommon Malignancy Presenting a Treatment Challenge. ( 30454337 )
2018
36
PD-L1 expression in pancreatic adenosquamous carcinoma: PD-L1 expression is limited to the squamous component. ( 30477643 )
2018
37
Atypical presentation of adenosquamous carcinoma: A case report. ( 30574311 )
2018
38
Adenosquamous Carcinoma of the Choledochus. ( 30686962 )
2018
39
[The efficacy and influence factors analysis of EGFR TKIs on patients with lung adenosquamous carcinoma]. ( 30392343 )
2018
40
Adenosquamous Carcinoma of the Esophagus: An NCDB-Based Investigation on Comparative Features and Overall Survival in a Rare Tumor. ( 28848104 )
2017
41
Gastric adenosquamous carcinoma producing granulocyte-colony stimulating factor: a case of a rare malignancy. ( 28493097 )
2017
42
Adenosquamous Carcinoma of the Pancreas Demonstrated on 18F-FDG PET/CT Imaging. ( 28098663 )
2017
43
Clinical outcomes of epidermal growth factor receptor tyrosine kinase inhibitors in recurrent adenosquamous carcinoma of the lung after resection. ( 28123305 )
2017
44
Primary Hepatic Adenosquamous Carcinoma Associated with Primary Sclerosing Cholangitis. ( 29258074 )
2017
45
Expression of hormone receptors in low-grade adenosquamous carcinoma of the breast: A case report. ( 29145336 )
2017
46
CD117 expression in adenosquamous carcinoma. ( 28766737 )
2017
47
Genomic signatures of pancreatic adenosquamous carcinoma (PASC). ( 28722109 )
2017
48
Clinical implications of the proliferative ability of the squamous component regarding tumor progression of adenosquamous carcinoma of the pancreas: A preliminary report. ( 28784574 )
2017
49
Pancreatic adenosquamous carcinoma and intraductal papillary mucinous neoplasm in a<i>CDKN2A</i>germline mutation carrier. ( 28979722 )
2017
50
Importance of tumor extent in adenosquamous carcinoma of the head and neck: a retrospective cohort study. ( 28412233 )
2017
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Variations for Adenosquamous Carcinoma

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Expression for Adenosquamous Carcinoma

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Search GEO for disease gene expression data for Adenosquamous Carcinoma.
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Pathways for Adenosquamous Carcinoma

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Pathways related to Adenosquamous Carcinoma according to GeneCards Suite gene sharing:

(show all 37)
# Super pathways Score Top Affiliating Genes
1
Gastric cancer 38
Show member pathways
 12.64 EGFR KRAS PIK3CA TP53
2
Downstream signaling events of B Cell Receptor (BCR) 67
Show member pathways
 12.59 EGFR KRAS PIK3CA TP53
3
Endometrial cancer 38
Show member pathways
 12.58 AR EGFR KRAS PIK3CA TP53
4
Pathways in cancer 38
12.53 AR EGFR KRAS PIK3CA TP53
5
Immune response IL-23 signaling pathway 23
Show member pathways
 12.39 EGFR KRAS PIK3CA TP53
6
ErbB signaling pathway 1 38
Show member pathways
 12.37 EGFR KRAS PIK3CA TP53
7
Cytoskeletal Signaling 4
12.34 KRT5 KRT7 KRT8 MUC1
8
mTOR signaling pathway (KEGG) 66
Show member pathways
 12.29 EGFR KRAS PIK3CA TP53
9
Apoptosis Pathway 73
Show member pathways
 12.2 EGFR KRAS PIK3CA TP53
10
Cellular senescence (KEGG) 38
12.05 KRAS PIK3CA TP53
11
mTOR Pathway 73
Show member pathways
 12.05 KRAS PIK3CA TP53
12
Development EGFR signaling via small GTPases 23
Show member pathways
 12.01 EGFR KRAS PIK3CA
13
Longevity regulating pathway 38
Show member pathways
 12.01 KRAS PIK3CA TP53
14
Transcription Androgen Receptor nuclear signaling 23
Show member pathways
 11.99 AR EGFR PIK3CA
15
MAPK Signaling: Mitogen Stimulation Pathway 66
Show member pathways
 11.98 EGFR KRAS PIK3CA TP53
16
Proteoglycans in cancer 38
11.97 EGFR KRAS PIK3CA TP53
17
FoxO signaling pathway 38
Show member pathways
 11.95 EGFR KRAS PIK3CA
18
UVA-Induced MAPK Signaling 65
Show member pathways
 11.92 EGFR KRAS TP53
19
Direct p53 effectors 1
11.92 EGFR TP53 TP63
20
MAPK Pathway 73
Show member pathways
 11.88 EGFR PIK3CA TP53
21
Sphingolipid signaling pathway 38
11.86 KRAS PIK3CA TP53
22
Thyroid hormone signaling pathway 38
11.84 KRAS PIK3CA TP53
23
DNA Damage Response (only ATM dependent) 1
11.83 KRAS PIK3CA TP53
24
MicroRNAs in cancer 38
11.83 EGFR KRAS PIK3CA TP53 TP63
25
Glioblastoma Multiforme 65
11.81 EGFR KRAS TP53
26
Cytoskeleton remodeling Neurofilaments 23
Show member pathways
 11.79 KRT5 KRT7 KRT8
27
Signaling by ERBB4 67
Show member pathways
 11.78 EGFR KRAS PIK3CA
28
AKT Signaling Pathway 68
11.78 EGFR KRAS PIK3CA TP53
29
Integrated Breast Cancer Pathway 1
11.75 AR EGFR KRAS TP53
30
Jak-Stat Signaling Pathway (sino) 68
11.74 EGFR KRAS PIK3CA
31
Bladder cancer 38 1
11.5 EGFR KRAS TP53
32
Transcription_Transcription factor Tubby signaling pathways 23
11.13 EGFR KRAS TP53
33
TP53 Network 1
Show member pathways
 11 TP53 TP63
34
E-cadherin signaling in keratinocytes 1
10.92 EGFR PIK3CA
35
Nongenotropic Androgen signaling 1
10.88 AR PIK3CA
36
G-protein signaling_K-RAS regulation pathway 23
10.76 EGFR KRAS PIK3CA
37
Central carbon metabolism in cancer 38
10.74 EGFR KRAS PIK3CA TP53
Sources

GO Terms for Adenosquamous Carcinoma

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Cellular components related to Adenosquamous Carcinoma according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 cytoplasm GO:0005737 9.7 AR EGFR KRAS KRT5 KRT7 KRT8
2 keratin filament GO:0045095 9.33 KRT5 KRT7 KRT8
3 nuclear chromatin GO:0000790 8.92 AR MUC1 TP53 TP63

Biological processes related to Adenosquamous Carcinoma according to GeneCards Suite gene sharing:

(show all 11)
# Name GO ID Score Top Affiliating Genes
1 cell proliferation GO:0008283 9.8 AR EGFR TP53 TP63
2 cytokine-mediated signaling pathway GO:0019221 9.67 KRAS MUC1 PIK3CA TP53
3 cornification GO:0070268 9.61 KRT5 KRT7 KRT8
4 liver development GO:0001889 9.5 EGFR KRAS PIK3CA
5 prostate gland development GO:0030850 9.48 AR TP63
6 maintenance of gastrointestinal epithelium GO:0030277 9.46 MUC4 SERPINA3
7 DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator GO:0006978 9.4 MUC1 TP53
8 stimulatory C-type lectin receptor signaling pathway GO:0002223 9.33 KRAS MUC1 MUC4
9 positive regulation of production of miRNAs involved in gene silencing by miRNA GO:1903800 9.26 EGFR TP53
10 morphogenesis of an epithelial fold GO:0060571 8.96 AR EGFR
11 epidermis development GO:0008544 8.92 EGFR KRT5 PTHLH TP63

Molecular functions related to Adenosquamous Carcinoma according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 chromatin binding GO:0003682 9.26 AR EGFR TP53 TP63
2 p53 binding GO:0002039 8.8 MUC1 TP53 TP63
Sources

Sources for Adenosquamous Carcinoma

About this section
3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
17 EFO
18 ExPASy
20 FMA
29 GO
30 GTR
31 HGMD
32 HMDB
33 HPO
34 ICD10
35 ICD10 via Orphanet
36 ICD9CM
37 IUPHAR
38 KEGG
39 LifeMap
41 LOVD
43 MedGen
45 MeSH
46 MESH via Orphanet
47 MGI
50 NCI
51 NCIt
52 NDF-RT
55 NINDS
56 Novoseek
58 OMIM
59 OMIM via Orphanet
63 PubMed
65 QIAGEN
70 SNOMED-CT via HPO
71 SNOMED-CT via Orphanet
72 TGDB
73 Tocris
74 UMLS
75 UMLS via Orphanet
The MalaCards human disease database index: 1-9 A B C D E F G H I J K L M N O P Q R S T U V W X Y Z
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