MCID: ADN005
MIFTS: 23

Adenosquamous Gallbladder Carcinoma

Categories: Cancer diseases, Gastrointestinal diseases

Aliases & Classifications for Adenosquamous Gallbladder Carcinoma

MalaCards integrated aliases for Adenosquamous Gallbladder Carcinoma:

Name: Adenosquamous Gallbladder Carcinoma 12 15
Adenosquamous Carcinoma of the Gallbladder 12
Adenosquamous Carcinoma of Gallbladder 12

Classifications:



External Ids:

Disease Ontology 12 DOID:5627
NCIt 50 C7356
UMLS 73 C1333741

Summaries for Adenosquamous Gallbladder Carcinoma

Disease Ontology : 12 A gallbladder carcinoma that derives from squamous cells and gland-like cells.

MalaCards based summary : Adenosquamous Gallbladder Carcinoma, also known as adenosquamous carcinoma of the gallbladder, is related to pancreatic cystadenocarcinoma and xanthogranulomatous cholecystitis. An important gene associated with Adenosquamous Gallbladder Carcinoma is SERPINA3 (Serpin Family A Member 3), and among its related pathways/superpathways is Autophagy - animal. Related phenotypes are Increased shRNA abundance (Z-score > 2) and Increased shRNA abundance (Z-score > 2)

Related Diseases for Adenosquamous Gallbladder Carcinoma

Diseases related to Adenosquamous Gallbladder Carcinoma via text searches within MalaCards or GeneCards Suite gene sharing:

(show all 12)
# Related Disease Score Top Affiliating Genes
1 pancreatic cystadenocarcinoma 10.0 CEACAM5 SERPINA3
2 xanthogranulomatous cholecystitis 10.0 CEACAM5 SERPINA3
3 breast cyst 9.9 CTSD SERPINA3
4 adenocarcinoma 9.9
5 adenosquamous carcinoma 9.9
6 secretory meningioma 9.9 CEACAM5 SERPINA3
7 alzheimer disease 2 9.8 CTSD SERPINA3
8 testicular yolk sac tumor 9.8 CEACAM5 SERPINA3
9 fibrosarcoma of bone 9.6 PDGFRA SERPINA3
10 rosai-dorfman disease 9.5 CTSD PDGFRA
11 dermatofibrosarcoma protuberans 9.3 PDGFRA SERPINA3
12 gastrointestinal system cancer 9.0 CEACAM5 PDGFRA

Graphical network of the top 20 diseases related to Adenosquamous Gallbladder Carcinoma:



Diseases related to Adenosquamous Gallbladder Carcinoma

Symptoms & Phenotypes for Adenosquamous Gallbladder Carcinoma

GenomeRNAi Phenotypes related to Adenosquamous Gallbladder Carcinoma according to GeneCards Suite gene sharing:

26 (show all 11)
# Description GenomeRNAi Source Accession Score Top Affiliating Genes
1 Increased shRNA abundance (Z-score > 2) GR00366-A-105 9.4 CTSD
2 Increased shRNA abundance (Z-score > 2) GR00366-A-115 9.4 CTSD
3 Increased shRNA abundance (Z-score > 2) GR00366-A-146 9.4 CTSD
4 Increased shRNA abundance (Z-score > 2) GR00366-A-163 9.4 HMGB1
5 Increased shRNA abundance (Z-score > 2) GR00366-A-176 9.4 HMGB1
6 Increased shRNA abundance (Z-score > 2) GR00366-A-6 9.4 CTSD HMGB1
7 Increased shRNA abundance (Z-score > 2) GR00366-A-69 9.4 HMGB1
8 Increased shRNA abundance (Z-score > 2) GR00366-A-73 9.4 CTSD
9 Increased shRNA abundance (Z-score > 2) GR00366-A-81 9.4 HMGB1
10 Increased shRNA abundance (Z-score > 2) GR00366-A-85 9.4 CTSD
11 Increased shRNA abundance (Z-score > 2) GR00366-A-99 9.4 CTSD

Drugs & Therapeutics for Adenosquamous Gallbladder Carcinoma

Search Clinical Trials , NIH Clinical Center for Adenosquamous Gallbladder Carcinoma

Genetic Tests for Adenosquamous Gallbladder Carcinoma

Anatomical Context for Adenosquamous Gallbladder Carcinoma

Publications for Adenosquamous Gallbladder Carcinoma

Articles related to Adenosquamous Gallbladder Carcinoma:

(show all 11)
# Title Authors Year
1
CD109 is a novel marker for squamous cell/adenosquamous carcinomas of the gallbladder. ( 26249215 )
2015
2
Squamous/adenosquamous carcinoma of the gallbladder: Analysis of 34 cases and comparison of clinicopathologic features and surgical outcomes with adenocarcinoma. ( 26458491 )
2015
3
Long-term survival of a patient with advanced adenosquamous carcinoma of the gallbladder after radical resection. ( 15868080 )
2005
4
Adenosquamous carcinoma of the gallbladder. ( 12239911 )
2002
5
Adenosquamous carcinoma of the gallbladder warrants resection only if curative resection is feasible. ( 12115390 )
2002
6
Advanced adenosquamous carcinoma of the gallbladder with bilio-biliary fistula: an uncommon case treated by hepatopancreatoduodenectomy. ( 10430314 )
1999
7
MRI findings in adenosquamous carcinoma of the gallbladder. ( 9543592 )
1998
8
Hepatopancreatoduodenectomy for squamous and adenosquamous carcinoma of the gallbladder. ( 7782034 )
1995
9
Adenosquamous carcinoma of the gallbladder: a clinicopathological, immunohistochemical and flow-cytometric study of twenty cases. ( 7911122 )
1994
10
Stromal osteoclast-like giant cells in an adenosquamous carcinoma of the gallbladder. ( 1592394 )
1992
11
Adenosquamous carcinoma of the gallbladder with spindle cell features. A light microscopic and immunocytochemical study of a case. ( 2437004 )
1987

Variations for Adenosquamous Gallbladder Carcinoma

Expression for Adenosquamous Gallbladder Carcinoma

Search GEO for disease gene expression data for Adenosquamous Gallbladder Carcinoma.

Pathways for Adenosquamous Gallbladder Carcinoma

Pathways related to Adenosquamous Gallbladder Carcinoma according to GeneCards Suite gene sharing:

# Super pathways Score Top Affiliating Genes
1 10.73 CTSD HMGB1

GO Terms for Adenosquamous Gallbladder Carcinoma

Cellular components related to Adenosquamous Gallbladder Carcinoma according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 extracellular region GO:0005576 9.46 CEACAM5 CTSD HMGB1 SERPINA3
2 ficolin-1-rich granule lumen GO:1904813 8.96 CTSD HMGB1
3 secretory granule lumen GO:0034774 8.62 HMGB1 SERPINA3

Biological processes related to Adenosquamous Gallbladder Carcinoma according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 autophagy GO:0006914 9.37 CTSD HMGB1
2 chemotaxis GO:0006935 9.32 HMGB1 PDGFRA
3 positive regulation of MAPK cascade GO:0043410 9.26 HMGB1 PDGFRA
4 positive regulation of cytosolic calcium ion concentration GO:0007204 9.16 HMGB1 PDGFRA
5 lung development GO:0030324 8.96 HMGB1 PDGFRA
6 neutrophil degranulation GO:0043312 8.8 CTSD HMGB1 SERPINA3

Sources for Adenosquamous Gallbladder Carcinoma

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
17 ExPASy
19 FMA
28 GO
29 GTR
30 HGMD
31 HMDB
32 HPO
33 ICD10
34 ICD10 via Orphanet
35 ICD9CM
36 IUPHAR
37 KEGG
38 LifeMap
40 LOVD
42 MedGen
44 MeSH
45 MESH via Orphanet
46 MGI
49 NCI
50 NCIt
51 NDF-RT
54 NINDS
55 Novoseek
57 OMIM
58 OMIM via Orphanet
62 PubMed
64 QIAGEN
69 SNOMED-CT via HPO
70 SNOMED-CT via Orphanet
71 TGDB
72 Tocris
73 UMLS
74 UMLS via Orphanet
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