MCID: ADH001
MIFTS: 40

Adhesions of Uterus

Categories: Reproductive diseases

Aliases & Classifications for Adhesions of Uterus

MalaCards integrated aliases for Adhesions of Uterus:

Name: Adhesions of Uterus 12 15 74
Intrauterine Adhesions 12 74
Intrauterine Synechiae 12
Asherman Syndrome 74
Band of Uterus 12

Classifications:



External Ids:

Disease Ontology 12 DOID:13812
SNOMED-CT 69 31107007
ICD10 34 N85.6

Summaries for Adhesions of Uterus

Disease Ontology : 12 A uterine disease that is characterized by the presence of scar tissue which attaches the uterus to another structure.

MalaCards based summary : Adhesions of Uterus, also known as intrauterine adhesions, is related to myoma and asherman's syndrome. An important gene associated with Adhesions of Uterus is ARHGAP29 (Rho GTPase Activating Protein 29), and among its related pathways/superpathways is Mesodermal Commitment Pathway. The drugs Dimenhydrinate and Hyaluronic acid have been mentioned in the context of this disorder. Affiliated tissues include uterus, bone and bone marrow, and related phenotypes are Decreased viability and Decreased viability

Related Diseases for Adhesions of Uterus

Diseases related to Adhesions of Uterus via text searches within MalaCards or GeneCards Suite gene sharing:

(show all 16)
# Related Disease Score Top Affiliating Genes
1 myoma 29.7 ESR1 HOXA10
2 asherman's syndrome 11.3
3 endometrial cancer 10.0
4 endometriosis 10.0 ESR1 HOXA10
5 endometriosis of ovary 10.0 ESR1 HOXA10
6 adenomyosis 10.0 ESR1 HOXA10
7 germ cell cancer 9.9 ESR1 POU5F1
8 uterine sarcoma 9.9 ESR1 PDGFRB
9 endometritis 9.9
10 amenorrhea 9.9
11 endometrial adenocarcinoma 9.9 ESR1 HOXA10
12 endometrial stromal sarcoma 9.8 ESR1 PDGFRB
13 hyperglycemia 9.7
14 infertility 9.7
15 rapidly involuting congenital hemangioma 9.7
16 chronic myelomonocytic leukemia 9.5 KDM6A PDGFRB

Graphical network of the top 20 diseases related to Adhesions of Uterus:



Diseases related to Adhesions of Uterus

Symptoms & Phenotypes for Adhesions of Uterus

GenomeRNAi Phenotypes related to Adhesions of Uterus according to GeneCards Suite gene sharing:

27
# Description GenomeRNAi Source Accession Score Top Affiliating Genes
1 Decreased viability GR00221-A-1 9.4 ESR1 PDGFRB
2 Decreased viability GR00221-A-2 9.4 ARHGAP29 ESR1
3 Decreased viability GR00221-A-3 9.4 PDGFRB
4 Decreased viability GR00221-A-4 9.4 ARHGAP29 ESR1 PDGFRB
5 Decreased viability GR00342-S-1 9.4 PDGFRB
6 Decreased viability GR00402-S-2 9.4 ARHGAP29 ESR1 PDGFRB

MGI Mouse Phenotypes related to Adhesions of Uterus:

47
# Description MGI Source Accession Score Top Affiliating Genes
1 digestive/alimentary MP:0005381 9.83 ARHGAP29 ESR1 HOXA10 PDGFRB POU5F1
2 embryo MP:0005380 9.8 ARHGAP29 ESR1 KDM6A PDGFRB POU5F1
3 growth/size/body region MP:0005378 9.8 ARHGAP29 ESR1 HOXA10 KDM6A LATS1 PDGFRB
4 endocrine/exocrine gland MP:0005379 9.77 ESR1 HOXA10 LATS1 PDGFRB POU5F1
5 mortality/aging MP:0010768 9.73 ARHGAP29 ESR1 KDM6A LATS1 PDGFRB POU5F1
6 nervous system MP:0003631 9.63 ESR1 HOXA10 KDM6A LATS1 PDGFRB POU5F1
7 normal MP:0002873 9.35 ESR1 KDM6A LATS1 PDGFRB POU5F1
8 reproductive system MP:0005389 9.1 ESR1 HOXA10 KDM6A LATS1 PDGFRB POU5F1

Drugs & Therapeutics for Adhesions of Uterus

Drugs for Adhesions of Uterus (from DrugBank, HMDB, Dgidb, PharmGKB, IUPHAR, NovoSeek, BitterDB):

(show top 50) (show all 61)
# Name Status Phase Clinical Trials Cas Number PubChem Id
1
Dimenhydrinate Approved Phase 4 523-87-5 441281
2
Hyaluronic acid Approved, Vet_approved Phase 4,Phase 3,Not Applicable,Early Phase 1 9004-61-9 53477741
3
Estradiol Approved, Investigational, Vet_approved Phase 4,Phase 1,Phase 2,Not Applicable 50-28-2 5757
4
Polyestradiol phosphate Approved Phase 4,Phase 1,Phase 2,Not Applicable 28014-46-2
5 Viscosupplements Phase 4,Not Applicable,Early Phase 1
6 Carboxymethylcellulose Sodium Phase 4
7 Adjuvants, Immunologic Phase 4,Not Applicable,Early Phase 1
8 Immunologic Factors Phase 4,Not Applicable,Early Phase 1
9 Pharmaceutical Solutions Phase 4,Not Applicable
10 Protective Agents Phase 4,Not Applicable,Early Phase 1
11 Contraceptive Agents Phase 4,Phase 3,Not Applicable
12 Hormones Phase 4,Phase 3,Phase 1,Phase 2,Not Applicable
13 Hormone Antagonists Phase 4,Phase 3,Phase 1,Phase 2,Not Applicable
14 Estradiol 17 beta-cypionate Phase 4,Phase 1,Phase 2,Not Applicable
15 Estradiol 3-benzoate Phase 4,Phase 1,Phase 2,Not Applicable
16 Progestins Phase 4,Phase 1,Phase 2,Not Applicable
17 Hormones, Hormone Substitutes, and Hormone Antagonists Phase 4,Phase 3,Phase 1,Phase 2,Not Applicable
18 Estrogens Phase 4,Phase 1,Phase 2,Not Applicable
19
Misoprostol Approved Phase 3 59122-46-2 5282381
20
Mifepristone Approved, Investigational Phase 3 84371-65-3 55245
21 Antacids Phase 3
22 Gastrointestinal Agents Phase 3
23 Oxytocics Phase 3
24 Luteolytic Agents Phase 3
25 Anti-Ulcer Agents Phase 3
26 Contraceptives, Oral Phase 3
27 Contraceptives, Postcoital Phase 3
28 Anesthetics Phase 2,Not Applicable
29 Anti-Bacterial Agents Phase 2
30 Antibiotics, Antitubercular Phase 2
31
Copper Approved, Investigational Not Applicable 7440-50-8 27099
32
Ethanol Approved Early Phase 1 64-17-5 702
33
Aspirin Approved, Vet_approved Not Applicable 50-78-2 2244
34
Progesterone Approved, Vet_approved Not Applicable 57-83-0 5994
35
Zaleplon Approved, Illicit, Investigational 151319-34-5 5719
36
Tetracaine Approved, Vet_approved Not Applicable 94-24-6 5411
37
Povidone-iodine Approved Not Applicable 25655-41-8
38
Iodine Approved, Investigational Not Applicable 7553-56-2 807
39
Povidone Approved Not Applicable 9003-39-8
40
Menotropins Approved Not Applicable 9002-68-0, 61489-71-2 5360545
41
Lenograstim Approved, Investigational Not Applicable 135968-09-1
42
Medroxyprogesterone acetate Approved, Investigational Not Applicable 71-58-9
43
Sargramostim Approved, Investigational Not Applicable 123774-72-1, 83869-56-1
44
carbamide peroxide Approved Not Applicable 124-43-6
45 Calamus Not Applicable
46 Anti-Inflammatory Agents Not Applicable
47 Fibrinolytic Agents Not Applicable
48 Peripheral Nervous System Agents Not Applicable
49 Anti-Inflammatory Agents, Non-Steroidal Not Applicable
50 Antipyretics Not Applicable

Interventional clinical trials:

(show top 50) (show all 57)
# Name Status NCT ID Phase Drugs
1 Treatment of Infertility by Collagen Scaffold Loaded With Autologous Bone Marrow Stem Cells Unknown status NCT02204358 Phase 4
2 Seprafilm Slurry in the Prevention of Uterine Scarring in Patients Undergoing Hysteroscopic Myomectomy Unknown status NCT01632202 Phase 4
3 Effectiveness of Hyaluronic Acid Gel in the Prevention of Intrauterine Adhesions After Second Trimester Abortion Unknown status NCT02868437 Phase 4
4 Safety of Leaving Cook Balloon Uterine Stent in Uterus for One Month Completed NCT01167296 Phase 4
5 Estrogen in the Prevention of Adhesion Reformation Enrolling by invitation NCT03620929 Phase 4 Estradiol Valerate
6 Cervical Preparation for Surgical Abortion at 12-14 Weeks: a Prospective, Randomized, Evaluator-blinded, Multicenter, Controlled Comparison Between Mifepristone, Misoprostol and Their Combination Unknown status NCT01795599 Phase 3 Mifegyne ®;Gymiso®
7 Hyaluronic Acid and Uterine Synechiae Active, not recruiting NCT02248376 Phase 3 Gel
8 Comparison of Different Doses of Oestrogen Therapy for Preventing Intrauterine Adhesion Completed NCT02726971 Phase 1, Phase 2 Femoston
9 Platelet-rich Plasma (PRP) for Endometrial Regeneration and Repair Completed NCT02825849 Phase 2
10 Treatment of Severe Asherman Syndrome by Collagen Scaffold Loaded With Autologous Bone Marrow Mononuclear Cells Recruiting NCT02680366 Phase 2
11 the Safety/Efficacy of Umbilical Cord Mesenchymal Stem Cell (19#iSCLife®-CSD) Therapy for Patients With Healing Poor After Uterus Injury Not yet recruiting NCT03386708 Phase 2 Normal saline (NS)
12 Myomectomy During Cesarean Section Completed NCT03095014 Phase 1
13 Efficiency of Amnion Graft to Prevent Intrauterine Adhesions After Hysteroscopic Surgery Unknown status NCT02132104 Not Applicable Femoston
14 The Efficacy and Safety of the Dried Biological Amnion Graft in Patients With Intrauterine Adhesions Unknown status NCT02496052 Not Applicable estradiol valerate tablets+dydrogesterone Tablets
15 Efficiency of INTERCOAT (Oxiplex/AP Gel) in Preventing Intrauterine Adhesion Formation in Hysteroscopic Surgery Unknown status NCT01637974 Not Applicable INTERCOAT administration
16 Prevention of Intrauterine Adhesions After Hysteroscopic Metroplasty With Autocross-linked Hyaluronic Acid Gel Unknown status NCT02404454 Not Applicable
17 Comparing the Efficacy of Intrauterine Balloon and Intrauterine Contraceptive Device for the Therapy of Uterine Adhesion Unknown status NCT02867202 Not Applicable
18 Safety Study of Use of Hyaluronic Acid Gel To Prevent Intrauterine Adhesions In Hysteroscopic Surgery Unknown status NCT01464528 Early Phase 1 Hyaluronan
19 The Efficacy of A New Crosslinked Hyaluronan Gel in Prevention of Intrauterine Adhesion Completed NCT03353909 Not Applicable
20 The Value of Using Platelet Rich Plasma After Hysteroscopic Lysis of Severe Intrauterine Adhesions Completed NCT03541746 Not Applicable
21 Role of Chronic Endometritis in Postoperative Recurrence of Severe Intrauterine Adhesions Completed NCT02744807
22 Effects of Aspirin on Uterine Endometrial Repair Severe Intrauterine Adhesion Completed NCT02744716 Not Applicable Aspirin
23 Efficacy and Safety of Crosslinked Hyaluronan Gel for Preventing Intrauterine Adhesion Completed NCT02220621 Not Applicable
24 Hyaluronic Acid Gel in Prevention of Intrauterine Adhesions After Endometrial Ablation Completed NCT01829451 Not Applicable
25 Efficiency of Intercoat (Oxiplex/AP Gel)in Decreasing Intrauterine Adhesions Completed NCT01377779 Not Applicable Oxiplex/AP gel;Normal Saline
26 Treatment of Infertility by Collagen Scaffold Loaded With Umbilical Cord Derived Mesenchyma Stem Cells Completed NCT02313415 Not Applicable
27 Intrauterine Adhesion Rate After Hysteroscopic Myomectomy and Application of HYALOBARRIER Gel Completed NCT01412489 Not Applicable
28 Impact of Mindfulness Based Stress Reduction on Anxiety, Depression and QOL in Women With Intrauterine Adhesion. Completed NCT02746679 Not Applicable
29 Reproductive Outcome Affected by Two Adjunctive Treatments in Patients With Severe Intrauterine Adhesions Completed NCT02708277 Not Applicable
30 Platelet Rich Plasma Following Hysteroscopic Adhesolysis Completed NCT03881215 Not Applicable
31 Evaluation of Uterine Patency Following Sonography-guided Transcervical Ablation of Fibroids Completed NCT02844920
32 Postoperative Analgesic Efficacy of Tetracaine Hydrochloride Gel Completed NCT02863679 Not Applicable Tetracaine hydrochloride gel
33 UACE Followed by Uterine Suction Curettage for the Treatment of Caesarean Scar Pregnancy Completed NCT02357095 Not Applicable
34 Sonohysterography , 3D Ultrasonography and Hysteroscopy in Assessment of Uterine Factor in Cases of Female Infertility Completed NCT02399501 Not Applicable
35 Treatment of Intrauterine Adhesions and Its Distribution of Genital Tract Flora Recruiting NCT03731689 Not Applicable Intrauterine lavage therapy;Intrauterine gel-injection therapy
36 Comparing Intra Uterine Synechiae Occurence Using Bipolar Energy Compared With Monopolar Energy in Myoma Resection on Women Having Menorraghia and/or Infertility Recruiting NCT02661087 Not Applicable
37 Intrauterine Balloon Dilatation Therapy in the Prevention of Adhesion Formation After Hysteroscopic Myomectomy Recruiting NCT03169478 Not Applicable
38 Comparing the Efficacy of Two Methods in the Prevention of Adhesion Reformation After Hysteroscopic Adhesiolysis Recruiting NCT03346317 Not Applicable estradiol valerate tablets+dydrogesterone tablets
39 Comparing the Efficacy of Two Methods for the Therapy of Uterine Adhesion Recruiting NCT03329898 Not Applicable estradiol valerate tablets;dydrogesterone Tablets
40 Intrauterine Balloon Therapy to Prevent the Recurrence of Intrauterine Adhesions Recruiting NCT03131596 Not Applicable
41 HMG Stimulation Versus HRT for Endometrial Preparation Prior to Blastocyst Transfer in Moderate to Severe IUA Patients Recruiting NCT03578172 Not Applicable human menopausal gonadotrophin;hormone replacement therapy
42 The Efficacy of Estrogen Therapy Against Adhesion Reformation After Hysteroscopic Adhesiolysis Recruiting NCT03351205 Not Applicable estradiol valerate tablets+dydrogesterone tablets
43 The Efficacy and Safety of Disposable Balloon Uterine Stent in Patients With Asherman Syndrome Recruiting NCT03330873 Not Applicable
44 The Efficacy of G-CSF Against Adhesion Reformation After Hysteroscopic Adhesiolysis Recruiting NCT02855632 Not Applicable G-CSF;Normal saline;hormone therapy
45 Immediate and Delayed Intrauterine Balloon in the Prevention of Adhesion Reformation After Hysteroscopic Adhesiolysis Recruiting NCT03171454 Not Applicable
46 Clinical Study of Umbilical Cord Mesenchymal Stem Cells Combined With Collagen Scaffold in the Treatment of Thin Endometrium Recruiting NCT03724617 Not Applicable umbilical cord mesenchymal stem cells combined with collagen scaffold
47 Effect of Pelvic Floor Muscle Electrophysiologic Therapy on Enhanced Recovery After Gynecologic Surgery Recruiting NCT03524807 Not Applicable
48 Use of an Intra Uterine Balloon to Prevent Recurrent Adhesions (REpAIR) Recruiting NCT03446755 Not Applicable
49 The Hysteroscopic Morcellator (HM). Recruiting NCT01537822 Not Applicable
50 Pre-clinical Endometrial Tissular Renovation Study Active, not recruiting NCT03665649 Not Applicable

Search NIH Clinical Center for Adhesions of Uterus

Genetic Tests for Adhesions of Uterus

Anatomical Context for Adhesions of Uterus

MalaCards organs/tissues related to Adhesions of Uterus:

42
Uterus, Bone, Bone Marrow, Small Intestine, Placenta

Publications for Adhesions of Uterus

Articles related to Adhesions of Uterus:

(show top 50) (show all 134)
# Title Authors Year
1
Factors that Impact Fertility after Hysteroscopic Adhesiolysis for Intrauterine Adhesions and Amenorrhea: A Retrospective Cohort Study. ( 30880159 )
2019
2
New Crosslinked Hyaluronan Gel for the Prevention of Intrauterine Adhesions after Dilation and Curettage in Patients with Delayed Miscarriage: A Prospective, Multicenter, Randomized, Controlled Trial. ( 29678756 )
2019
3
New Crosslinked Hyaluronan Gel, Intrauterine Device, or Both for the Prevention of Intrauterine Adhesions. ( 30846896 )
2019
4
Morphological appearance of uterine cavity on ultrasound prior to development of intrauterine adhesions. ( 28236322 )
2018
5
The different dosages of estrogen affect endometrial fibrosis and receptivity, but not SDF-1/CXCR4 axis in the treatment of intrauterine adhesions. ( 28531361 )
2018
6
Small Intestine Submucosa Is a Potential Material for Intrauterine Adhesions Treatment in a Rat Model. ( 28723687 )
2018
7
The Effect of Adjuvant Treatment to Prevent and Treat Intrauterine Adhesions: A Network Meta-Analysis of Randomized Controlled Trials. ( 28893657 )
2018
8
Feasibility analysis of treating severe intrauterine adhesions by transplanting menstrual blood-derived stem cells. ( 29393381 )
2018
9
Intrauterine adhesions following an induced termination of pregnancy: a nationwide cohort study. ( 29532588 )
2018
10
Abnormal expression of fibrosis markers, estrogen receptor α and stromal derived factor‑1/chemokine (C‑X‑C motif) receptor‑4 axis in intrauterine adhesions. ( 29568895 )
2018
11
The link between intrauterine adhesions and induced termination of pregnancy remains a challenge. ( 29626375 )
2018
12
Creation of a rabbit model for intrauterine adhesions using electrothermal injury. ( 29732749 )
2018
13
Human mesenchymal stem cell-derived extracellular vesicles/estrogen combined therapy safely ameliorates experimentally induced intrauterine adhesions in a female rat model. ( 29954457 )
2018
14
MicroRNA‑326 inhibits endometrial fibrosis by regulating TGF‑β1/Smad3 pathway in intrauterine adhesions. ( 29956752 )
2018
15
Live birth rate and obstetric complications following the hysteroscopic management of intrauterine adhesions including Asherman syndrome. ( 30239778 )
2018
16
Two Cases of Intrauterine Adhesions with Rare Hysteroscopic Findings. ( 30319136 )
2018
17
Efficacy of a New Crosslinked Hyaluronan Gel in the Prevention of Intrauterine Adhesions. ( 30524185 )
2018
18
Expression of SOX2, NANOG and OCT4 in a mouse model of lipopolysaccharide-induced acute uterine injury and intrauterine adhesions. ( 28253866 )
2017
19
Prevalence and Impact of Chronic Endometritis in Patients With Intrauterine Adhesions: A Prospective Cohort Study. ( 27773811 )
2017
20
Hysteroscopic Myomectomy can lead to intrauterine adhesions and infertility. ( 28585608 )
2017
21
Ultrasound-guided treatment of intrauterine adhesions in the outpatient setting. ( 27420903 )
2017
22
Oxidized, Regenerated Cellulose Adhesion Barrier Plus Intrauterine Device Prevents Recurrence After Adhesiolysis for Moderate to Severe Intrauterine Adhesions. ( 27742483 )
2017
23
Reproductive Outcomes in Patients With Intrauterine Adhesions Following Hysteroscopic Adhesiolysis: Experience From the Largest Women's Hospital in China. ( 27856386 )
2017
24
Efficacy of freeze-dried amnion graft following hysteroscopic adhesiolysis of severe intrauterine adhesions. ( 28170094 )
2017
25
Dominant factors affecting reproductive outcomes of fertility-desiring young women with intrauterine adhesions. ( 28233115 )
2017
26
Human amniotic mesenchymal stromal cell transplantation improves endometrial regeneration in rodent models of intrauterine adhesions. ( 28285950 )
2017
27
Prevalence of intrauterine adhesions after the application of hyaluronic acid gel after dilatation and curettage in women with at least one previous curettage: short-term outcomes of a multicenter, prospective randomized controlled trial. ( 28390688 )
2017
28
AAGL Practice Report: Practice Guidelines on Intrauterine Adhesions Developed in Collaboration With the European Society of Gynaecological Endoscopy (ESGE). ( 28473177 )
2017
29
AAGL practice report: practice guidelines on intrauterine adhesions developed in collaboration with the European Society of Gynaecological Endoscopy (ESGE). ( 28603474 )
2017
30
Safety and Efficacy of Amnion Graft in Preventing Reformation of Intrauterine Adhesions. ( 28807808 )
2017
31
Three-dimensional structure micelles of heparin-poloxamer improve the therapeutic effect of 17β-estradiol on endometrial regeneration for intrauterine adhesions in a rat model. ( 28848344 )
2017
32
Assessment of Risk Factors of Intrauterine Adhesions in Patients With Induced Abortion and the Curative Effect of Hysteroscopic Surgery. ( 28972429 )
2017
33
Commentary on "Assessment of Risk Factors of Intrauterine Adhesions in Patients with Induced Abortion and the Curative Effect of Hysteroscopic Surgery". ( 29252055 )
2017
34
Clinico-hysteroscopic analysis of severe intrauterine adhesions among Nigerian infertile women. ( 29629012 )
2017
35
Hysteroscopic Resection in Fertility-Sparing Surgery for Atypical Hyperplasia and Endometrial Cancer: How Important Are Intrauterine Adhesions? ( 26724716 )
2016
36
Reply to "Hysteroscopic Resection in Fertility-Sparing Surgery for Atypical Hyperplasia and Endometrial Cancer: How Important Are Intrauterine Adhesions?". ( 26724717 )
2016
37
The influence of the location and extent of intrauterine adhesions on recurrence after hysteroscopic adhesiolysis. ( 25753391 )
2016
38
Interceed and Estrogen Reduce Uterine Adhesions and Fibrosis and Improve Endometrial Receptivity in a Rabbit Model of Intrauterine Adhesions. ( 26895816 )
2016
39
Intrauterine Adhesions Following Miscarriage: Look and Learn. ( 27261221 )
2016
40
Prevalence of intrauterine adhesions after termination of pregnancy: a systematic review. ( 27436757 )
2016
41
Application of Bone Marrow-Derived Mesenchymal Stem Cells in the Treatment of Intrauterine Adhesions in Rats. ( 27614987 )
2016
42
Intrauterine Adhesions: Causes and Treatment Outcomes among Thai Women ( 29952186 )
2016
43
The Overexpression of TGF-I^ and CCN2 in Intrauterine Adhesions Involves the NF-I_B Signaling Pathway. ( 26719893 )
2015
44
Hysteroscopic Procedure for Type I Myoma With Intrauterine Adhesions. ( 27678645 )
2015
45
Hysteroscopic Resection in Fertility-Sparing Surgery for Atypical Hyperplasia and Endometrial Cancer: How Important Are Intrauterine Adhesions? ( 26205575 )
2015
46
Reply to "Hysteroscopic Resection in Fertility-Sparing Surgery for Atypical Hyperplasia and Endometrial Cancer: How Important are Intrauterine Adhesions?". ( 26205576 )
2015
47
Preventive effect of oral mucosal epithelial cell sheets on intrauterine adhesions. ( 25475585 )
2015
48
Intrauterine adhesions after hysteroscopic treatment for retained products of conception: what are the risk factors? ( 25527235 )
2015
49
Subendometrial blood flow changes by 3-dimensional power Doppler ultrasound after hysteroscopic lysis of severe intrauterine adhesions: preliminary study. ( 25573184 )
2015
50
Ultrasound and intrauterine adhesions: a novel structured approach to diagnosis and management. ( 26094824 )
2015

Variations for Adhesions of Uterus

Expression for Adhesions of Uterus

Search GEO for disease gene expression data for Adhesions of Uterus.

Pathways for Adhesions of Uterus

Pathways related to Adhesions of Uterus according to GeneCards Suite gene sharing:

# Super pathways Score Top Affiliating Genes
1
Show member pathways
11.28 KDM6A LATS1 POU5F1

GO Terms for Adhesions of Uterus

Biological processes related to Adhesions of Uterus according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 intracellular signal transduction GO:0035556 9.61 ARHGAP29 LATS1 PDGFRB
2 regulation of gene expression GO:0010468 9.5 HOXA10 KDM6A POU5F1
3 response to estradiol GO:0032355 9.48 ESR1 PDGFRB
4 chromatin remodeling GO:0006338 9.46 ESR1 KDM6A
5 response to estrogen GO:0043627 9.4 ESR1 PDGFRB
6 positive regulation of fibroblast proliferation GO:0048146 9.37 ESR1 PDGFRB
7 uterus development GO:0060065 9.26 ESR1 HOXA10
8 regulation of intracellular estrogen receptor signaling pathway GO:0033146 9.16 ESR1 LATS1
9 positive regulation of phospholipase C activity GO:0010863 8.96 ESR1 PDGFRB
10 male gonad development GO:0008584 8.8 ESR1 HOXA10 PDGFRB

Molecular functions related to Adhesions of Uterus according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 RNA polymerase II proximal promoter sequence-specific DNA binding GO:0000978 9.5 ESR1 HOXA10 KDM6A
2 protein kinase binding GO:0019901 9.43 ESR1 LATS1 PDGFRB
3 phosphatidylinositol-4,5-bisphosphate 3-kinase activity GO:0046934 9.16 ESR1 PDGFRB
4 estrogen receptor binding GO:0030331 8.96 ESR1 LATS1
5 sequence-specific DNA binding GO:0043565 8.92 ESR1 HOXA10 KDM6A POU5F1

Sources for Adhesions of Uterus

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20 FMA
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35 ICD10 via Orphanet
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45 MeSH
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70 SNOMED-CT via HPO
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75 UMLS via Orphanet
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