MCID: ADH006
MIFTS: 27

Adhesive Otitis Media

Categories: Ear diseases

Aliases & Classifications for Adhesive Otitis Media

MalaCards integrated aliases for Adhesive Otitis Media:

Name: Adhesive Otitis Media 12 15
Adhesive Middle Ear Disease 72 33
Chronic Adhesive Otitis Media 12

Classifications:



External Ids:

Disease Ontology 12 DOID:11235
ICD9CM 35 385.1 385.10
SNOMED-CT 68 7699004
ICD10 33 H74.1
UMLS 72 C0155478

Summaries for Adhesive Otitis Media

Disease Ontology : 12 An auditory system disease that is characterized by a thin retracted ear drum becomes sucked into the middle-ear space and stuck (i.e., adherent) to the ossicles and other bones of the middle ear.

MalaCards based summary : Adhesive Otitis Media, also known as adhesive middle ear disease, is related to otitis media and cholesteatoma of middle ear. An important gene associated with Adhesive Otitis Media is PLAT (Plasminogen Activator, Tissue Type), and among its related pathways/superpathways are Glioma and Immune response IFN alpha/beta signaling pathway. Affiliated tissues include bone and testes, and related phenotype is reproductive system.

Wikipedia : 75 Tympanic membrane retraction describes a condition in which a part of the eardrum lies deeper within the... more...

Related Diseases for Adhesive Otitis Media

Diseases related to Adhesive Otitis Media via text searches within MalaCards or GeneCards Suite gene sharing:

(show all 13)
# Related Disease Score Top Affiliating Genes
1 otitis media 10.8
2 cholesteatoma of middle ear 10.4
3 ataxia, combined cerebellar and peripheral, with hearing loss and diabetes mellitus 10.3
4 otosclerosis 10.2
5 sensorineural hearing loss 10.1
6 neuritis 10.1
7 cleft palate, isolated 10.0
8 branchiootic syndrome 1 10.0
9 mastoiditis 10.0
10 hyperacusis 10.0
11 brain compression 9.7 PLAT FGF2
12 vascular disease 9.4 PLAT FGF2
13 clivus chordoma 9.4 FGF2 ATM

Graphical network of the top 20 diseases related to Adhesive Otitis Media:



Diseases related to Adhesive Otitis Media

Symptoms & Phenotypes for Adhesive Otitis Media

MGI Mouse Phenotypes related to Adhesive Otitis Media:

46
# Description MGI Source Accession Score Top Affiliating Genes
1 reproductive system MP:0005389 8.8 ATM FGF2 PLAT

Drugs & Therapeutics for Adhesive Otitis Media

Interventional clinical trials:


# Name Status NCT ID Phase Drugs
1 Comparison of Half-thickness Tragal Cartilage Graft to Temporalis Fascia Graft Completed NCT03817242

Search NIH Clinical Center for Adhesive Otitis Media

Genetic Tests for Adhesive Otitis Media

Anatomical Context for Adhesive Otitis Media

MalaCards organs/tissues related to Adhesive Otitis Media:

41
Bone, Testes

Publications for Adhesive Otitis Media

Articles related to Adhesive Otitis Media:

(show top 50) (show all 125)
# Title Authors PMID Year
1
Transcanal Endoscopic Tympanoplasty for Pediatric Patients Under 15 Years of Age With Chronic Otitis Media. 38
31370387 2019
2
Treatment of adhesive otitis media by tympanoplasty combined with fascia grafting catheterization. 38
31273447 2019
3
Cartilage tympanoplasty combined with eustachian tube balloon dilatation in the treatment of adhesive otitis media. 38
30485447 2019
4
[The application of cartilage in middle ear surgery]. 38
30550140 2018
5
Effect of esterified hyaluronic acid as middle ear packing in tympanoplasty for adhesive otitis media. 38
29073815 2018
6
Outcomes of type I tympanoplasty using a cartilage shield graft in patients with poor prognostic factors. 38
27955869 2017
7
Postoperative Mastoid Aeration Following Canal Wall Up Mastoidectomy according to Preoperative Middle Ear Disease: Analysis of Temporal Bone Computed Tomography Scans. 38
28942628 2017
8
Impact of pharyngofixation in cleft palate repair surgery on the development of chronic adhesive otitis media. 38
28325168 2017
9
Autologous human nasal epithelial cell sheet using temperature-responsive culture insert for transplantation after middle ear surgery. 38
25846100 2017
10
The effects of surgery type and different ossiculoplasty materials on the hearing results in cholesteatoma surgery. 38
27837423 2017
11
Presence of osteoclasts in middle ear cholesteatoma: a study of undecalcified bone sections. 38
27575923 2017
12
Middle ear mucosal regeneration by tissue-engineered cell sheet transplantation. 38
29302343 2017
13
Tympanoplasty in adhesive otitis media: A descriptive study. 38
27167089 2016
14
Middle ear mucosal regeneration with three-dimensionally tissue-engineered autologous middle ear cell sheets in rabbit model. 38
23894137 2016
15
[Cholesteatoma of the external and middle ear in the childhood]. 38
25909669 2015
16
[Hearing disorders in young subjects]. 38
24577027 2014
17
Alternative to canal wall-down mastoidectomy for sclerotic mastoid cavities: epitympanoplasty with mastoid obliteration. 38
24574423 2014
18
Is cartilage better than temporalis muscle fascia in type I tympanoplasty? Implications for current surgical practice. 38
23321796 2013
19
Outcomes of cochlear implantation in children with CHARGE syndrome. 38
24125186 2013
20
Improvement of eustachian tube function by tissue-engineered regeneration of mastoid air cells. 38
23086494 2013
21
A technique for concurrent procedure of mastoid obliteration and meatoplasty after canal wall down mastoidectomy. 38
22321811 2012
22
Radiologic analysis of high jugular bulb by computed tomography. 38
22722144 2012
23
Mastoid obliteration with silicone blocks after canal wall down mastoidectomy. 38
22468198 2012
24
[Transmeatal aerodynamical otoendoscopy for otitis media]. 38
23250522 2012
25
[Diagnosis and treatment of adhesive otitis media]. 38
21874685 2011
26
[Functional multispiral computed tomography of sound-transmitting structures in the middle ear]. 38
21720292 2011
27
Long-term middle-ear ventilation with subannular tubes. 38
20403228 2010
28
Cochlear implantation in patients with chronic otitis media. 38
20189327 2010
29
[Tragus cartilage tympanoplasty for treatment of adhesive otitis media]. 38
20584683 2010
30
New morphometric findings in adhesive otitis media: petroclival angle and eustachian tube-tympanic cavity ventilation angle. 38
19427144 2010
31
[Cartilage palisade tympanoplasty for adhesive otitis media]. 38
19610589 2009
32
Mastoid obliteration using calcium phosphate bone paste with an artificial dermis soaked with basic fibroblast growth factor: preliminary clinical report. 38
18485642 2009
33
Cochlear implantation in atelectasis and chronic otitis media: long-term follow-up. 38
18520585 2008
34
Eustachian tube function and the middle ear. 38
17097443 2006
35
Dehiscent high jugular bulb: a pitfall in middle ear surgery. 38
16788425 2006
36
The role of multifrequency tympanometry in otitis media. 38
16532097 2006
37
Practical use of MESNA in atelectatic ears and adhesive otitis media. 38
16479146 2006
38
[Clinical manifestation of attic retraction pocket]. 38
16320713 2005
39
Regeneration of mastoid air cells in clinical applications by in situ tissue engineering. 38
15689745 2005
40
[Computed tomography of the temporal bone in diagnosis of adhesive otitis media]. 38
16025931 2005
41
Management of hemorrhagic high jugular bulb with adhesive otitis media in an only hearing ear: transcatheter endovascular embolization using detachable coils. 38
15633900 2004
42
[Potentialities of temporal bone computed tomography in the identification of causes of hypoacusis of postinflammatory genesis]. 38
15626228 2004
43
Körner's septum (petrosquamosal lamina) and chronic ear disease. 38
14586561 2004
44
[Operative therapy of the adhesive otitis media]. 38
15127568 2004
45
Tympanostomy preceding tympanoplasty: could it be a new approach for the management of adhesive otitis media. 38
14967090 2003
46
[A method for preventing recurrent scarring of the tympatic cavity in surgical treatment of patients with suppurative otitis media]. 38
14605663 2003
47
Gross dehiscence of the bone covering the facial nerve in the light of otological surgery. 38
12437834 2002
48
[A rare case of the high jugular bulb associated with only hearing ear]. 38
12235884 2002
49
Otological and audiological outcomes five years after tympanostomy in early childhood. 38
12150521 2002
50
[Use of NiTi shape memory alloys in the eustachian tube to prevent and treat adhesive middle ear]. 38
12768796 2002

Variations for Adhesive Otitis Media

Expression for Adhesive Otitis Media

Search GEO for disease gene expression data for Adhesive Otitis Media.

Pathways for Adhesive Otitis Media

Pathways related to Adhesive Otitis Media according to GeneCards Suite gene sharing:

# Super pathways Score Top Affiliating Genes
1
Show member pathways
11.92 FGF2 ATM
2
Show member pathways
11.47 FGF2 ATM
3 11.43 PLAT ATM
4 10.77 PLAT FGF2
5 10.31 PLAT FGF2

GO Terms for Adhesive Otitis Media

Biological processes related to Adhesive Otitis Media according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 response to hypoxia GO:0001666 8.96 PLAT ATM
2 phosphatidylinositol-3-phosphate biosynthetic process GO:0036092 8.32 ATM

Molecular functions related to Adhesive Otitis Media according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 1-phosphatidylinositol-3-kinase activity GO:0016303 8.32 ATM

Sources for Adhesive Otitis Media

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
17 EFO
18 ExPASy
19 FMA
28 GO
29 GTR
30 HGMD
31 HMDB
32 HPO
33 ICD10
34 ICD10 via Orphanet
35 ICD9CM
36 IUPHAR
37 KEGG
38 LifeMap
40 LOVD
42 MedGen
44 MeSH
45 MESH via Orphanet
46 MGI
49 NCI
50 NCIt
51 NDF-RT
54 NINDS
55 Novoseek
57 OMIM
58 OMIM via Orphanet
62 PubMed
64 QIAGEN
69 SNOMED-CT via HPO
70 TGDB
71 Tocris
72 UMLS
73 UMLS via Orphanet
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