MCID: ADH006
MIFTS: 26

Adhesive Otitis Media

Categories: Ear diseases

Aliases & Classifications for Adhesive Otitis Media

MalaCards integrated aliases for Adhesive Otitis Media:

Name: Adhesive Otitis Media 12 15
Chronic Adhesive Otitis Media 12
Adhesive Middle Ear Disease 74

Classifications:



External Ids:

Disease Ontology 12 DOID:11235
ICD9CM 36 385.1 385.10
SNOMED-CT 69 7699004
ICD10 34 H74.1
UMLS 74 C0155478

Summaries for Adhesive Otitis Media

Disease Ontology : 12 An auditory system disease that is characterized by a thin retracted ear drum becomes sucked into the middle-ear space and stuck (i.e., adherent) to the ossicles and other bones of the middle ear.

MalaCards based summary : Adhesive Otitis Media, also known as chronic adhesive otitis media, is related to otitis media and cleft palate, isolated. An important gene associated with Adhesive Otitis Media is PLAT (Plasminogen Activator, Tissue Type), and among its related pathways/superpathways are Glioma and Immune response IFN alpha/beta signaling pathway. Affiliated tissues include bone and brain, and related phenotype is reproductive system.

Wikipedia : 77 Tympanic membrane retraction describes a condition in which a part of the eardrum lies deeper within the... more...

Related Diseases for Adhesive Otitis Media

Diseases related to Adhesive Otitis Media via text searches within MalaCards or GeneCards Suite gene sharing:

# Related Disease Score Top Affiliating Genes
1 otitis media 10.7
2 cleft palate, isolated 10.0
3 mastoiditis 10.0
4 cholesteatoma of middle ear 10.0
5 brain compression 9.8 FGF2 PLAT
6 vascular disease 9.6 FGF2 PLAT
7 clivus chordoma 9.6 ATM FGF2

Graphical network of the top 20 diseases related to Adhesive Otitis Media:



Diseases related to Adhesive Otitis Media

Symptoms & Phenotypes for Adhesive Otitis Media

MGI Mouse Phenotypes related to Adhesive Otitis Media:

47
# Description MGI Source Accession Score Top Affiliating Genes
1 reproductive system MP:0005389 8.8 ATM FGF2 PLAT

Drugs & Therapeutics for Adhesive Otitis Media

Search Clinical Trials , NIH Clinical Center for Adhesive Otitis Media

Genetic Tests for Adhesive Otitis Media

Anatomical Context for Adhesive Otitis Media

MalaCards organs/tissues related to Adhesive Otitis Media:

42
Bone, Brain

Publications for Adhesive Otitis Media

Articles related to Adhesive Otitis Media:

(show all 24)
# Title Authors Year
1
Cartilage tympanoplasty combined with eustachian tube balloon dilatation in the treatment of adhesive otitis media. ( 30485447 )
2019
2
Effect of esterified hyaluronic acid as middle ear packing in tympanoplasty for adhesive otitis media. ( 29073815 )
2018
3
Impact of pharyngofixation in cleft palate repair surgery on the development of chronic adhesive otitis media. ( 28325168 )
2017
4
Tympanoplasty in adhesive otitis media: A descriptive study. ( 27167089 )
2016
5
New morphometric findings in adhesive otitis media: petroclival angle and eustachian tube-tympanic cavity ventilation angle. ( 19427144 )
2010
6
Practical use of MESNA in atelectatic ears and adhesive otitis media. ( 16479146 )
2006
7
Management of hemorrhagic high jugular bulb with adhesive otitis media in an only hearing ear: transcatheter endovascular embolization using detachable coils. ( 15633900 )
2004
8
Tympanostomy preceding tympanoplasty: could it be a new approach for the management of adhesive otitis media. ( 14967090 )
2003
9
A guinea pig model of adhesive otitis media and the effect of tympanostomy. ( 10648067 )
2000
10
Comparison of polydioxanone and silicone plastic in the prevention of adhesive otitis media in the Mongolian gerbil. ( 7838554 )
1995
11
Transplantation of nasal mucosa into the middle ear for the treatment of adhesive otitis media. ( 3673803 )
1987
12
Surgery of chronic adhesive otitis media. ( 4040822 )
1985
13
Otosurgery of incipient adhesive otitis media in children. ( 6715966 )
1984
14
Surgical management of attic retraction and chronic adhesive otitis media. ( 6528727 )
1984
15
Adhesive otitis media. ( 6582196 )
1983
16
Tympanoplasty in chronic adhesive otitis media. ( 5061257 )
1972
17
Adhesive otitis media. An approach to its treatment. ( 5481614 )
1970
18
Middle ear cholesteatoma--etiology, relation to chronic adhesive otitis media, and treatment: an otophotographic study. ( 5357344 )
1969
19
Reversibility of chronic adhesive otitis media with polyethylene tube, middle ear air-vent, kodachrome time lapse study. ( 5940817 )
1966
20
ADHESIVE OTITIS MEDIA IN AUDIOLOGY. ( 14143614 )
1964
21
Fibrosing mastoiditis; its relation to adhesive otitis media, granulomas of the facial nerve and the conservation of hearing. ( 13521628 )
1958
22
Bony fixation of the stapes due to chronic adhesive otitis media; a clinico-pathological study. ( 13367635 )
1956
23
Chronic adhesive otitis media. ( 13367633 )
1956
24
Mucous Polypus presenting at the Pharyngeal Orifice of the left Eustachian Tube in a Man suffering from Bilateral Chronic Adhesive Otitis Media. ( 19974636 )
1910

Variations for Adhesive Otitis Media

Expression for Adhesive Otitis Media

Search GEO for disease gene expression data for Adhesive Otitis Media.

Pathways for Adhesive Otitis Media

Pathways related to Adhesive Otitis Media according to GeneCards Suite gene sharing:

# Super pathways Score Top Affiliating Genes
1
Show member pathways
11.92 ATM FGF2
2
Show member pathways
11.47 ATM FGF2
3 11.43 ATM PLAT
4 10.77 FGF2 PLAT
5 10.31 FGF2 PLAT

GO Terms for Adhesive Otitis Media

Biological processes related to Adhesive Otitis Media according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 response to hypoxia GO:0001666 8.96 ATM PLAT
2 phosphatidylinositol-3-phosphate biosynthetic process GO:0036092 8.32 ATM

Molecular functions related to Adhesive Otitis Media according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 1-phosphatidylinositol-3-kinase activity GO:0016303 8.32 ATM

Sources for Adhesive Otitis Media

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
17 EFO
18 ExPASy
20 FMA
29 GO
30 GTR
31 HGMD
32 HMDB
33 HPO
34 ICD10
35 ICD10 via Orphanet
36 ICD9CM
37 IUPHAR
38 KEGG
39 LifeMap
41 LOVD
43 MedGen
45 MeSH
46 MESH via Orphanet
47 MGI
50 NCI
51 NCIt
52 NDF-RT
55 NINDS
56 Novoseek
58 OMIM
59 OMIM via Orphanet
63 PubMed
65 QIAGEN
70 SNOMED-CT via HPO
71 SNOMED-CT via Orphanet
72 TGDB
73 Tocris
74 UMLS
75 UMLS via Orphanet
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