MCID: ADS001
MIFTS: 25

Adiaspiromycosis

Categories: Infectious diseases, Respiratory diseases, Skin diseases

Aliases & Classifications for Adiaspiromycosis

MalaCards integrated aliases for Adiaspiromycosis:

Name: Adiaspiromycosis 12 15 74

Classifications:



External Ids:

Disease Ontology 12 DOID:0050072
UMLS 74 C0259737

Summaries for Adiaspiromycosis

Disease Ontology : 12 A primary systemic mycosis that is a fungal infection located in lungs, or located in skin, which results in disseminated granulomatous pulmonary process and cutaneous infection in rodents, small wild mammals and humans, has material basis in Chrysosporium parvum or Emmonsia crescens.

MalaCards based summary : Adiaspiromycosis is related to respiratory failure and acute conjunctivitis. An important gene associated with Adiaspiromycosis is LLGL1 (LLGL Scribble Cell Polarity Complex Component 1), and among its related pathways/superpathways are Cytoskeletal Signaling and Tight junction. Affiliated tissues include lung, skin and liver, and related phenotypes are Increased shRNA abundance (Z-score > 2) and Increased shRNA abundance (Z-score > 2)

Related Diseases for Adiaspiromycosis

Diseases related to Adiaspiromycosis via text searches within MalaCards or GeneCards Suite gene sharing:

# Related Disease Score Top Affiliating Genes
1 respiratory failure 10.2
2 acute conjunctivitis 10.0
3 uveitis 10.0
4 pulmonary tuberculosis 10.0
5 adenocarcinoma 10.0
6 conjunctivitis 10.0
7 acquired immunodeficiency syndrome 10.0
8 anterior uveitis 10.0

Graphical network of the top 20 diseases related to Adiaspiromycosis:



Diseases related to Adiaspiromycosis

Symptoms & Phenotypes for Adiaspiromycosis

GenomeRNAi Phenotypes related to Adiaspiromycosis according to GeneCards Suite gene sharing:

27 (show all 18)
# Description GenomeRNAi Source Accession Score Top Affiliating Genes
1 Increased shRNA abundance (Z-score > 2) GR00366-A-100 9.6 NT5M
2 Increased shRNA abundance (Z-score > 2) GR00366-A-11 9.6 ACTB
3 Increased shRNA abundance (Z-score > 2) GR00366-A-115 9.6 NT5M
4 Increased shRNA abundance (Z-score > 2) GR00366-A-128 9.6 NT5M
5 Increased shRNA abundance (Z-score > 2) GR00366-A-132 9.6 ACTB
6 Increased shRNA abundance (Z-score > 2) GR00366-A-151 9.6 ACTB
7 Increased shRNA abundance (Z-score > 2) GR00366-A-16 9.6 NT5M
8 Increased shRNA abundance (Z-score > 2) GR00366-A-161 9.6 NT5M
9 Increased shRNA abundance (Z-score > 2) GR00366-A-189 9.6 ACTB
10 Increased shRNA abundance (Z-score > 2) GR00366-A-201 9.6 ACTB
11 Increased shRNA abundance (Z-score > 2) GR00366-A-21 9.6 ACTB
12 Increased shRNA abundance (Z-score > 2) GR00366-A-215 9.6 NT5M
13 Increased shRNA abundance (Z-score > 2) GR00366-A-42 9.6 NT5M
14 Increased shRNA abundance (Z-score > 2) GR00366-A-52 9.6 ACTB
15 Increased shRNA abundance (Z-score > 2) GR00366-A-57 9.6 ACTB NT5M
16 Increased shRNA abundance (Z-score > 2) GR00366-A-65 9.6 NT5M
17 Increased shRNA abundance (Z-score > 2) GR00366-A-70 9.6 NT5M
18 Increased shRNA abundance (Z-score > 2) GR00366-A-85 9.6 NT5M

Drugs & Therapeutics for Adiaspiromycosis

Search Clinical Trials , NIH Clinical Center for Adiaspiromycosis

Genetic Tests for Adiaspiromycosis

Anatomical Context for Adiaspiromycosis

MalaCards organs/tissues related to Adiaspiromycosis:

42
Lung, Skin, Liver

The Foundational Model of Anatomy Ontology organs/tissues related to Adiaspiromycosis:

20
Skin, Lungs

Publications for Adiaspiromycosis

Articles related to Adiaspiromycosis:

(show top 50) (show all 80)
# Title Authors Year
1
Adiaspiromycosis in a wild European rabbit, and a review of the literature. ( 29717642 )
2018
2
Pulmonary adiaspiromycosis in critically endangered northern hairy-nosed wombats (Lasiorhinus krefftii). ( 29076222 )
2017
3
Pulmonary adiaspiromycosis in the Eurasian beaver (Castor fiber) inhabiting Poland. ( 29166284 )
2017
4
First detection of adiaspiromycosis in the lungs of a deer. ( 25787928 )
2015
5
First description of adiaspiromycosis in an Eurasian otter (Lutra lutra) in Italy. ( 25273962 )
2014
6
Disseminated pulmonary adiaspiromycosis in a crested porcupine (Hystrix cristata Linnaeus, 1758). ( 22493137 )
2012
7
Adiaspiromycosis of an Apodemus agrarius captured wild rodent in Korea. ( 22474477 )
2012
8
Adiaspiromycosis causing respiratory failure and a review of human infections due to Emmonsia and Chrysosporium spp. ( 22259200 )
2012
9
Disseminated adiaspiromycosis: case report of a liver transplant patient with human immunodeficiency infection, and literature review. ( 21323828 )
2011
10
Adiaspiromycosis mimicking widespread malignancy in a patient with pulmonary adenocarcinoma. ( 19734484 )
2009
11
Adiaspiromycosis due to Emmonsia crescens is widespread in native British mammals. ( 19533414 )
2009
12
Acute conjunctivitis with episcleritis and anterior uveitis linked to adiaspiromycosis and freshwater sponges, Amazon region, Brazil, 2005. ( 19331759 )
2009
13
Molecular diagnosis of disseminated adiaspiromycosis due to Emmonsia crescens. ( 19244459 )
2009
14
Fine needle aspiration of pulmonary adiaspiromycosis: a case report. ( 17425208 )
2007
15
Pulmonary adiaspiromycosis in a European hedgehog (Erinaceus europaeus) in Portugal. ( 16501161 )
2006
16
Cutaneous adiaspiromycosis: a distinct dermatologic entity associated with Chrysosporium species. ( 15577766 )
2004
17
Disseminated pulmonary adiaspiromycosis caused by Emmonsia crescens in a horse. ( 12462193 )
2002
18
Pulmonary adiaspiromycosis: report of two cases. ( 11064585 )
2000
19
Fatal adiaspiromycosis in a wild Eurasian otter (Lutra lutra). ( 11014486 )
2000
20
Pulmonary adiaspiromycosis in raccoons (Procyon lotor) from Oregon. ( 12968748 )
1999
21
Adiaspiromycosis in a European beaver from Sweden. ( 10231764 )
1999
22
Pulmonary adiaspiromycosis in a patient with acquired immunodeficiency syndrome. ( 10691202 )
1999
23
Molecular genetic variation in Emmonsia crescens and Emmonsia parva, etiologic agents of adiaspiromycosis, and their phylogenetic relationship to Blastomyces dermatitidis (Ajellomyces dermatitidis) and other systemic fungal pathogens. ( 9738044 )
1998
24
Pulmonary adiaspiromycosis in a two year old girl. ( 9059367 )
1997
25
Acute pulmonary adiaspiromycosis. Report of three cases and a review of 16 other cases collected from the literature. ( 15538822 )
1997
26
Adiaspiromycosis in bullfrogs (Rana catesbeiana). ( 8953541 )
1996
27
Disseminated adiaspiromycosis in a patient with AIDS. ( 8483061 )
1993
28
Adiaspiromycosis in suspected cases of pulmonary tuberculosis in the common brushtail possum (Trichosurus vulpecula). ( 16031725 )
1993
29
Adiaspiromycosis: an unusual fungal infection of the lung. Report of 11 cases. ( 8352373 )
1993
30
Fulminant disseminated pulmonary adiaspiromycosis in humans. ( 1539748 )
1992
31
Adiaspiromycosis. An uncommon disease caused by an unusual pathogen. ( 2331897 )
1990
32
Respiratory failure caused by adiaspiromycosis. ( 2331914 )
1990
33
Adiaspiromycosis treated successfully with ketoconazole. ( 2795406 )
1989
34
Adiaspiromycosis in striped skunks in Alberta, Canada. ( 3951052 )
1986
35
Two cases of adiaspiromycosis in the Japanese pika (Ochotona hyperborea yesoensis Kishida). ( 3981833 )
1985
36
Comparative susceptibility of the agents of adiaspiromycosis to imidazole derivatives in vitro. ( 6314565 )
1983
37
Mutants of Chrysosporium parvum var. crescens--a causative agent of adiaspiromycosis. ( 6229148 )
1983
38
Pulmonary adiaspiromycosis of some free living small mammals in the north Moravian region: pathologic findings and experimental-biological observations. ( 6242567 )
1982
39
Disseminated pulmonary adiaspiromycosis identified in bioptic material from the lung. ( 6892182 )
1982
40
Adiaspiromycosis in south Australian hairy-nosed wombats (Lasiorhinus latifrons). ( 7201528 )
1982
41
A serological proof of adiaspiromycosis in wild rodents. ( 7450616 )
1980
42
Adiaspiromycosis in Tasmanian wombats? ( 7393314 )
1980
43
Adiaspiromycosis of human skin caused by Emmonsia crescens. ( 575679 )
1979
44
The prevalence of adiaspiromycosis in three sympatric species of ground squirrels. ( 567700 )
1978
45
Adiaspiromycosis. ( 364386 )
1978
46
Adiaspiromycosis in the lungs of a goat. ( 566741 )
1978
47
Avirulence and decreased virulence in mutants of Emmonsia crescens, a causative agent of adiaspiromycosis. ( 560338 )
1977
48
Importance of free living mustelid carnivores in circulation of adiaspiromycosis. ( 559252 )
1977
49
Adiaspiromycosis in Czechoslovakian mammals. ( 564081 )
1977
50
Adiaspiromycosis in the Franklin's ground squirrel, Spermophilus franklini, and pika, Ochotona princeps, from Alberta, Canada. ( 943581 )
1976

Variations for Adiaspiromycosis

Expression for Adiaspiromycosis

Search GEO for disease gene expression data for Adiaspiromycosis.

Pathways for Adiaspiromycosis

Pathways related to Adiaspiromycosis according to GeneCards Suite gene sharing:

# Super pathways Score Top Affiliating Genes
1 11.64 ACTB LLGL1
2 11.19 ACTB LLGL1
3 10.81 ACTB LLGL1

GO Terms for Adiaspiromycosis

Molecular functions related to Adiaspiromycosis according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 nucleotide binding GO:0000166 8.62 ACTB NT5M

Sources for Adiaspiromycosis

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
17 EFO
18 ExPASy
20 FMA
29 GO
30 GTR
31 HGMD
32 HMDB
33 HPO
34 ICD10
35 ICD10 via Orphanet
36 ICD9CM
37 IUPHAR
38 KEGG
39 LifeMap
41 LOVD
43 MedGen
45 MeSH
46 MESH via Orphanet
47 MGI
50 NCI
51 NCIt
52 NDF-RT
55 NINDS
56 Novoseek
58 OMIM
59 OMIM via Orphanet
63 PubMed
65 QIAGEN
70 SNOMED-CT via HPO
71 SNOMED-CT via Orphanet
72 TGDB
73 Tocris
74 UMLS
75 UMLS via Orphanet
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