MCID: ADS001
MIFTS: 26

Adiaspiromycosis

Categories: Infectious diseases, Respiratory diseases, Skin diseases

Aliases & Classifications for Adiaspiromycosis

MalaCards integrated aliases for Adiaspiromycosis:

Name: Adiaspiromycosis 12 15 71

Classifications:



External Ids:

Disease Ontology 12 DOID:0050072
UMLS 71 C0259737

Summaries for Adiaspiromycosis

Disease Ontology : 12 A primary systemic mycosis that is a fungal infection located in lungs, or located in skin, which results in disseminated granulomatous pulmonary process and cutaneous infection in rodents, small wild mammals and humans, has material basis in Chrysosporium parvum or Emmonsia crescens.

MalaCards based summary : Adiaspiromycosis is related to respiratory failure and miliary tuberculosis. An important gene associated with Adiaspiromycosis is EGFLAM (EGF Like, Fibronectin Type III And Laminin G Domains), and among its related pathways/superpathways are ATP/ITP metabolism and Transcription of tRNA. Affiliated tissues include lungs, skin and lung.

Related Diseases for Adiaspiromycosis

Diseases related to Adiaspiromycosis via text searches within MalaCards or GeneCards Suite gene sharing:

(show all 31)
# Related Disease Score Top Affiliating Genes
1 respiratory failure 10.4
2 miliary tuberculosis 10.3
3 immune deficiency disease 10.2
4 histoplasmosis 10.2
5 lung disease 10.2
6 mesothelioma, malignant 10.0
7 sarcoidosis 1 10.0
8 human immunodeficiency virus type 1 10.0
9 aspergillosis 10.0
10 osteomyelitis 10.0
11 asbestosis 10.0
12 silicosis 10.0
13 anthracosis 10.0
14 siderosis 10.0
15 acute conjunctivitis 10.0
16 blastomycosis 10.0
17 uveitis 10.0
18 fungal infectious disease 10.0
19 constipation 10.0
20 benign mesothelioma 10.0
21 pulmonary tuberculosis 10.0
22 adenocarcinoma 10.0
23 tinea favosa 10.0
24 conjunctivitis 10.0
25 acquired immunodeficiency syndrome 10.0
26 peritonitis 10.0
27 iridocyclitis 10.0
28 yellow fever 10.0
29 tuberculous peritonitis 10.0
30 rare mycosis 10.0
31 asbestos intoxication 10.0

Graphical network of the top 20 diseases related to Adiaspiromycosis:



Diseases related to Adiaspiromycosis

Symptoms & Phenotypes for Adiaspiromycosis

Drugs & Therapeutics for Adiaspiromycosis

Search Clinical Trials , NIH Clinical Center for Adiaspiromycosis

Genetic Tests for Adiaspiromycosis

Anatomical Context for Adiaspiromycosis

The Foundational Model of Anatomy Ontology organs/tissues related to Adiaspiromycosis:

19
Lungs, Skin

MalaCards organs/tissues related to Adiaspiromycosis:

40
Lung, Skin, Lymph Node, Liver

Publications for Adiaspiromycosis

Articles related to Adiaspiromycosis:

(show top 50) (show all 152)
# Title Authors PMID Year
1
Causes of Mortality and Lesions Observed Post mortem in European Moles (Talpa europaea) in Cornwall, South-west England. 61
30898293 2019
2
Adiaspiromycosis in a wild European rabbit, and a review of the literature. 61
29717642 2018
3
Pulmonary adiaspiromycosis in critically endangered northern hairy-nosed wombats (Lasiorhinus krefftii). 61
29076222 2017
4
Pulmonary adiaspiromycosis in the Eurasian beaver (Castor fiber) inhabiting Poland. 61
29166284 2017
5
First detection of adiaspiromycosis in the lungs of a deer. 61
25787928 2015
6
Invasive pulmonary infection caused by Chrysosporium articulatum: the first case report. 61
25366105 2015
7
First description of adiaspiromycosis in an Eurasian otter (Lutra lutra) in Italy. 61
25273962 2014
8
Causes of mortality and pathological lesions observed post-mortem in red squirrels (Sciurus vulgaris) in Great Britain. 61
24238087 2013
9
A dimorphic fungus causing disseminated infection in South Africa. 61
24106934 2013
10
Disseminated pulmonary adiaspiromycosis in a crested porcupine (Hystrix cristata Linnaeus, 1758). 61
22493137 2012
11
Adiaspiromycosis causing respiratory failure and a review of human infections due to Emmonsia and Chrysosporium spp. 61
22259200 2012
12
Adiaspiromycosis of an Apodemus agrarius captured wild rodent in Korea. 61
22474477 2012
13
Disseminated adiaspiromycosis: case report of a liver transplant patient with human immunodeficiency infection, and literature review. 61
21323828 2011
14
[Pulmonary adiaspiromycosis treated without antifungal drugs]. 61
20305978 2010
15
Adiaspiromycosis due to Emmonsia crescens is widespread in native British mammals. 61
19533414 2009
16
Adiaspiromycosis mimicking widespread malignancy in a patient with pulmonary adenocarcinoma. 61
19734484 2009
17
Molecular diagnosis of disseminated adiaspiromycosis due to Emmonsia crescens. 61
19244459 2009
18
Acute conjunctivitis with episcleritis and anterior uveitis linked to adiaspiromycosis and freshwater sponges, Amazon region, Brazil, 2005. 61
19331759 2009
19
Aleutian disease serology, protein electrophoresis, and pathology of the European mink (Mustela lutreola) from Navarra, Spain. 61
18816991 2008
20
Fine needle aspiration of pulmonary adiaspiromycosis: a case report. 61
17425208 2007
21
Pulmonary adiaspiromycosis in a European hedgehog (Erinaceus europaeus) in Portugal. 61
16501161 2006
22
Cutaneous adiaspiromycosis: a distinct dermatologic entity associated with Chrysosporium species. 61
15577766 2004
23
[Human adiaspiromycosis: cicatricial lesions in mediastinal lymph nodes]. 61
15094906 2004
24
Disseminated pulmonary adiaspiromycosis caused by Emmonsia crescens in a horse. 61
12462193 2002
25
[Pulmonary adiaspiromycosis: casual finding in a patient who died of yellow fever]. 61
11340501 2001
26
[Contribution to the morphologic diagnosis of lung adiaspiromycosis]. 61
11064587 2000
27
Pulmonary adiaspiromycosis: report of two cases. 61
11064585 2000
28
Fatal adiaspiromycosis in a wild Eurasian otter (Lutra lutra). 61
11014486 2000
29
[Adiaspiromycosis, 2 cases of incidental finding]. 61
10617808 1999
30
Pulmonary adiaspiromycosis in a patient with acquired immunodeficiency syndrome. 61
10691202 1999
31
Pulmonary adiaspiromycosis in raccoons (Procyon lotor) from Oregon. 61
12968748 1999
32
Adiaspiromycosis in a European beaver from Sweden. 61
10231764 1999
33
Molecular genetic variation in Emmonsia crescens and Emmonsia parva, etiologic agents of adiaspiromycosis, and their phylogenetic relationship to Blastomyces dermatitidis (Ajellomyces dermatitidis) and other systemic fungal pathogens. 61
9738044 1998
34
Acute pulmonary adiaspiromycosis. Report of three cases and a review of 16 other cases collected from the literature. 61
15538822 1997
35
[Human adiaspiromycosis. A report of a case treated with ketoconazole]. 61
9463198 1997
36
[Disseminated pulmonary adiaspiromycosis. A case report]. 61
9380900 1997
37
Pulmonary adiaspiromycosis in a two year old girl. 61
9059367 1997
38
Adiaspiromycosis in bullfrogs (Rana catesbeiana). 61
8953541 1996
39
Ajellomyces crescens sp. nov., taxonomy of Emmonsia spp., and relatedness with Blastomyces dermatitidis (teleomorph Ajellomyces dermatitidis). 61
8912163 1996
40
Adiaspiromycosis in suspected cases of pulmonary tuberculosis in the common brushtail possum (Trichosurus vulpecula). 61
16031725 1993
41
Adiaspiromycosis: an unusual fungal infection of the lung. Report of 11 cases. 61
8352373 1993
42
Disseminated adiaspiromycosis in a patient with AIDS. 61
8483061 1993
43
Fulminant disseminated pulmonary adiaspiromycosis in humans. 61
1539748 1992
44
[Pulmonary adiaspiromycosis]. 61
1766990 1991
45
Review of animal mycoses in Australia. 61
2233984 1990
46
[Human pulmonary adiaspiromycosis. A new case of disseminated form]. 61
2131496 1990
47
Adiaspiromycosis. An uncommon disease caused by an unusual pathogen. 61
2331897 1990
48
Respiratory failure caused by adiaspiromycosis. 61
2331914 1990
49
The in vitro susceptibility of some mycotic agents to a new orally active triazole, itraconazole. 61
2170505 1990
50
[A fatal case of human pulmonary adiaspiromycosis]. 61
2694306 1989

Variations for Adiaspiromycosis

Expression for Adiaspiromycosis

Search GEO for disease gene expression data for Adiaspiromycosis.

Pathways for Adiaspiromycosis

Pathways related to Adiaspiromycosis according to GeneCards Suite gene sharing:

# Super pathways Score Top Affiliating Genes
1 10.89 POLR3G POLR3C
2
Show member pathways
10.23 POLR3G POLR3C

GO Terms for Adiaspiromycosis

Cellular components related to Adiaspiromycosis according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 cell junction GO:0030054 9.13 PARVA KCNB1 EGFLAM
2 RNA polymerase III complex GO:0005666 8.62 POLR3G POLR3C

Biological processes related to Adiaspiromycosis according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 defense response to virus GO:0051607 9.32 POLR3G POLR3C
2 positive regulation of type I interferon production GO:0032481 9.26 POLR3G POLR3C
3 positive regulation of interferon-beta production GO:0032728 9.16 POLR3G POLR3C
4 positive regulation of innate immune response GO:0045089 8.96 POLR3G POLR3C
5 regulation of transcription by RNA polymerase III GO:0006359 8.62 POLR3G POLR3C

Molecular functions related to Adiaspiromycosis according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 DNA-directed 5'-3' RNA polymerase activity GO:0003899 8.62 POLR3G POLR3C

Sources for Adiaspiromycosis

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
17 EFO
18 ExPASy
19 FMA
28 GO
29 GTR
30 HMDB
31 HPO
32 ICD10
33 ICD10 via Orphanet
34 ICD9CM
35 IUPHAR
36 KEGG
37 LifeMap
39 LOVD
41 MedGen
43 MeSH
44 MESH via Orphanet
45 MGI
48 NCI
49 NCIt
50 NDF-RT
53 NINDS
54 Novoseek
56 OMIM
57 OMIM via Orphanet
61 PubMed
63 QIAGEN
68 SNOMED-CT via HPO
69 TGDB
70 Tocris
71 UMLS
72 UMLS via Orphanet
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