Home
User Guide
What's in a MalaCard Search Guide Our Sources
Analysis Tools
GeneCards GeneAnalytics GeneAlaCart PathCards VarElect TGex
News and Views Disease Lists/Categories
About
About MalaCards Our Publications Weizmann Institute LifeMap Discovery® Terms of Use MalaCards Team
MCID: ADR041
MIFTS: 46

Adrenal Cortical Adenoma

Categories: Cancer diseases, Endocrine diseases
Genes Tissues Related diseases Publications Pathways Drugs
Sources

Aliases & Classifications for Adrenal Cortical Adenoma

About this section

MalaCards integrated aliases for Adrenal Cortical Adenoma:

Name: Adrenal Cortical Adenoma 12 15 74
Adrenocortical Adenoma 12 17
Adenoma Adrenocortical 56

Classifications:

MalaCards categories:
Global: Cancer diseases
Anatomical: Endocrine diseases
See all MalaCards categories (disease lists)


External Ids:

Disease Ontology 12 DOID:0050891
UMLS 74 C0206667
Sources

Summaries for Adrenal Cortical Adenoma

About this section
Disease Ontology : 12 An adrenal adenoma that is a benign tumor of the adrenal cortex.

MalaCards based summary : Adrenal Cortical Adenoma, also known as adrenocortical adenoma, is related to adrenal adenoma and conn's syndrome. An important gene associated with Adrenal Cortical Adenoma is SYP (Synaptophysin), and among its related pathways/superpathways are Cytochrome P450 - arranged by substrate type and DAG and IP3 signaling. The drugs Racepinephrine and Epinephrine have been mentioned in the context of this disorder. Affiliated tissues include cortex, adrenal cortex and adrenal gland, and related phenotypes are Increased transferrin (TF) endocytosis and behavior/neurological

Wikipedia : 77 A adrenocortical adenoma is a benign tumor of the adrenal cortex.It can present with Cushing''s... more...

Sources

Related Diseases for Adrenal Cortical Adenoma

About this section

Diseases related to Adrenal Cortical Adenoma via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50) (show all 103)
# Related Disease Score Top Affiliating Genes
1 adrenal adenoma 30.8 CYP11A1 CYP11B1 CYP17A1 GIPR MC2R POMC
2 conn's syndrome 30.7 CYP11A1 CYP11B1 CYP17A1 GIPR MC2R POMC
3 adrenal carcinoma 30.6 CYP11A1 CYP11B1 CYP17A1 NR5A1 POMC SYP
4 gangliocytoma 30.5 POMC SYP
5 primary pigmented nodular adrenocortical disease 30.1 POMC PRKAR1A SYP
6 pituitary adenoma, prolactin-secreting 29.9 POMC PRKAR1A
7 pseudohermaphroditism 29.8 CYP17A1 NR5A1
8 hyperandrogenism 29.5 CYP17A1 POMC
9 lipoid congenital adrenal hyperplasia 28.6 CYP11A1 CYP11B1 CYP17A1 MC2R NR5A1 POMC
10 adrenocortical carcinoma, hereditary 26.8 CYP11A1 CYP11B1 CYP17A1 INHA MC2R NR5A1
11 adenoma 10.9
12 pheochromocytoma 10.4
13 spermatocele 10.3 NR5A1 SYP
14 adrenal gland pheochromocytoma 10.3
15 pancreatic endocrine carcinoma 10.3 POMC SYP
16 sella turcica neoplasm 10.3 POMC SYP
17 tuberculum sellae meningioma 10.2 POMC SYP
18 myxosarcoma 10.2 PRKAR1A SYP
19 olfactory nerve neoplasm 10.2 POMC SYP
20 abducens nerve disease 10.2 POMC SYP
21 cervix small cell carcinoma 10.2 POMC SYP
22 ovarian small cell carcinoma 10.2 INHA SYP
23 hyperaldosteronism, familial, type i 10.2 CYP11B1 POMC
24 cranial nerve malignant neoplasm 10.2 POMC SYP
25 cytochrome p450 oxidoreductase deficiency 10.2 CYP17A1 POMC
26 ectopic cushing syndrome 10.2 POMC SYP
27 granulosa cell tumor of the ovary 10.1 INHA SYP
28 familial adenomatous polyposis 10.1
29 endocrine organ benign neoplasm 10.1 CYP11B1 POMC SYP
30 cystadenoma 10.1 INHA SYP
31 glucocorticoid deficiency 1 10.1 MC2R POMC
32 renal cell carcinoma, nonpapillary 10.1
33 adrenal cortical carcinoma 10.1
34 angiosarcoma 10.1
35 ganglioneuroma 10.1
36 hemangioblastoma 10.1 INHA SYP
37 achalasia-addisonianism-alacrima syndrome 10.0 MC2R POMC
38 familial glucocorticoid deficiency 10.0 MC2R POMC
39 adrenal hyperplasia, congenital, due to 21-hydroxylase deficiency 10.0
40 hemihyperplasia, isolated 10.0
41 oncocytoma 10.0
42 thyroid cancer 10.0
43 thyroiditis 10.0
44 precocious puberty 10.0
45 sertoli cell tumor 10.0 INHA PRKAR1A SYP
46 cell type benign neoplasm 10.0 POMC SYP
47 acute adrenal insufficiency 10.0 CYP11A1 POMC
48 gonadal disease 9.9 NR5A1 POMC SULT2A1
49 beckwith-wiedemann syndrome 9.9
50 multiple endocrine neoplasia, type i 9.9

Graphical network of the top 20 diseases related to Adrenal Cortical Adenoma:



Diseases related to Adrenal Cortical Adenoma
Sources

Symptoms & Phenotypes for Adrenal Cortical Adenoma

About this section

GenomeRNAi Phenotypes related to Adrenal Cortical Adenoma according to GeneCards Suite gene sharing:

27
# Description GenomeRNAi Source Accession Score Top Affiliating Genes
1 Increased transferrin (TF) endocytosis GR00363-A 9.23 CYP11A1 CYP11B1 GIPR INHA MC2R POMC

MGI Mouse Phenotypes related to Adrenal Cortical Adenoma:

47
# Description MGI Source Accession Score Top Affiliating Genes
1 behavior/neurological MP:0005386 9.97 CYP11A1 CYP11B1 CYP17A1 MC2R NR5A1 POMC
2 cardiovascular system MP:0005385 9.87 CYP11A1 CYP11B1 INHA MC2R NR5A1 POMC
3 endocrine/exocrine gland MP:0005379 9.86 CYP11A1 CYP11B1 GIPR INHA MC2R NR5A1
4 growth/size/body region MP:0005378 9.76 CYP11A1 CYP11B1 CYP17A1 INHA MC2R NR5A1
5 homeostasis/metabolism MP:0005376 9.61 CYP11A1 CYP11B1 CYP17A1 GIPR INHA MC2R
6 mortality/aging MP:0010768 9.23 CYP11A1 CYP11B1 CYP17A1 INHA MC2R NR5A1
Sources

Drugs & Therapeutics for Adrenal Cortical Adenoma

About this section

Drugs for Adrenal Cortical Adenoma (from DrugBank, HMDB, Dgidb, PharmGKB, IUPHAR, NovoSeek, BitterDB):

(show top 50) (show all 82)
# Name Status Phase Clinical Trials Cas Number PubChem Id
1
Racepinephrine Approved Phase 4,Phase 3,Phase 2,Not Applicable 329-65-7 838
2
Epinephrine Approved, Vet_approved Phase 4,Phase 3,Phase 2,Not Applicable 51-43-4 5816
3 Vasoconstrictor Agents Phase 4,Phase 3,Not Applicable
4 Anti-Asthmatic Agents Phase 4,Phase 3,Not Applicable
5 Neurotransmitter Agents Phase 4,Phase 3,Not Applicable
6 Adrenergic beta-Agonists Phase 4,Phase 3,Not Applicable
7 Epinephryl borate Phase 4,Phase 3,Phase 2,Not Applicable
8 Peripheral Nervous System Agents Phase 4,Phase 3,Phase 2,Not Applicable
9 Autonomic Agents Phase 4,Phase 3,Phase 2,Not Applicable
10 Adrenergic alpha-Agonists Phase 4,Phase 3,Not Applicable
11 Mydriatics Phase 4,Phase 3,Not Applicable
12 Sympathomimetics Phase 4,Phase 3,Not Applicable
13 Adrenergic Agonists Phase 4,Phase 3,Not Applicable
14 Bronchodilator Agents Phase 4,Phase 3,Not Applicable
15 Adrenergic Agents Phase 4,Phase 3,Not Applicable
16 Respiratory System Agents Phase 4,Phase 3,Not Applicable
17
Hydrocortisone Approved, Vet_approved Phase 3,Phase 2,Not Applicable 50-23-7 5754
18
Mifepristone Approved, Investigational Phase 3 84371-65-3 55245
19
Hydrocortisone acetate Approved, Vet_approved Phase 3,Phase 2,Not Applicable 50-03-3
20
Etomidate Approved Phase 3 33125-97-2 667484 36339
21 Hormone Antagonists Phase 3,Phase 2,Not Applicable
22 Hormones, Hormone Substitutes, and Hormone Antagonists Phase 3,Phase 2,Not Applicable
23 Hormones Phase 3,Phase 2,Not Applicable
24 glucocorticoids Phase 3,Phase 2
25 Contraceptives, Postcoital Phase 3
26 Adrenocorticotropic Hormone Phase 3,Phase 2
27 Luteolytic Agents Phase 3
28 Contraceptive Agents Phase 3
29 Contraceptives, Oral Phase 3
30 Hydrocortisone 17-butyrate 21-propionate Phase 3,Phase 2,Not Applicable
31 beta-endorphin Phase 3
32 Hydrocortisone hemisuccinate Phase 3,Phase 2,Not Applicable
33 Melanocyte-Stimulating Hormones Phase 3
34 Central Nervous System Depressants Phase 3
35 Anesthetics Phase 3
36 Anesthetics, General Phase 3
37 Hypnotics and Sedatives Phase 3
38 Fluorodeoxyglucose F18 Phase 3
39 Anesthetics, Intravenous Phase 3
40
Dexamethasone acetate Approved, Investigational, Vet_approved Phase 2 1177-87-3
41
Dexamethasone Approved, Investigational, Vet_approved Phase 2 50-02-2 5743
42 Antineoplastic Agents, Hormonal Phase 2
43 Antiemetics Phase 2
44 Gastrointestinal Agents Phase 2
45 HIV Protease Inhibitors Phase 2
46 BB 1101 Phase 2
47 Anti-Inflammatory Agents Phase 2,Not Applicable
48
protease inhibitors Phase 2
49
Dopamine Approved 62-31-7, 51-61-6 681
50
Ethanol Approved 64-17-5 702

Interventional clinical trials:

(show all 36)
# Name Status NCT ID Phase Drugs
1 Influence of Synacthen Infusion on the Results of Adrenal Venous Sampling in Patient With Primary Aldosteronism Unknown status NCT02127840 Phase 4 Synacthen infusion during adrenal venous sampling
2 An Extension Study of CORLUX in the Treatment of Endogenous Cushing's Syndrome Completed NCT00936741 Phase 3 mifepristone
3 A Study of the Efficacy and Safety of CORLUX in the Treatment of Endogenous Cushing's Syndrome Completed NCT00569582 Phase 3 mifepristone
4 Combined FDG-PET and 123I-Iodometomidate Imaging for Adrenal Neoplasia Recruiting NCT02010957 Phase 3
5 A Study of the Efficacy and Safety of Relacorilant in Patients With Endogenous Cushing Syndrome Recruiting NCT03697109 Phase 3 Relacorilant
6 Medical Safety Follow-up Study for Patients Who Received More Than 28 Days of Total Exposure to BGG492 Completed NCT02150213 Phase 2 BGG492
7 Study of Efficacy and Safety of Osilodrostat in Cushing's Syndrome Completed NCT02468193 Phase 2 Osilodrostat
8 Study to Evaluate CORT125134 in Patients With Cushing's Syndrome Completed NCT02804750 Phase 2 CORT125134
9 Extension Study to Evaluate the Safety and Clinical Benefit of Long-Term Use of Relacorilant in Patients With Cushing Syndrome Recruiting NCT03604198 Phase 2 relacorilant
10 Study of Adrenalectomy Versus Observation for Subclinical Hypercortisolism Terminated NCT02001051 Phase 2
11 Laparoscopic Adrenalectomy Versus Radiofrequency Ablation Unknown status NCT02030587 Not Applicable
12 Does Serum-DXM Increase Diagnostic Accuracy of the Overnight DXM Suppression Test in the Work-up of Cushing's Syndrome? Unknown status NCT01504555
13 D2 Dopamine Receptor on Human Aldosterone-Producing Adenoma and Its Role in Aldosterone Secretion and Cell Proliferation Unknown status NCT00173446
14 Cardiovascular Risk in Patients With Non-Functional Adrenal Incidentaloma Completed NCT00768365
15 Rare Cystic Benign Adrenal Incidentalomas Completed NCT03739918
16 Laparoscopic Adrenalectomy for Large Adrenal Tumors. Completed NCT03830593
17 Comparison Between Posterior Retroperitoneoscopic Adrenalectomy and Laparoscopic Adrenalectomy Completed NCT01676025 Not Applicable
18 Surgery of Subclinical Cortisol Secreting Adrenal Incidentalomas Recruiting NCT02364089 Not Applicable Standardized medical treatment of hypertension by SAHR
19 Long-term Beneficial Metabolic Effects of Adrenalectomy in Subclinical Cushing's Syndrome of Adrenal Incidentaloma Recruiting NCT01382420 Not Applicable
20 Structured Evaluation of adRENal Tumors Discovered Incidentally - Prospectively Investigating the Testing Yield Recruiting NCT02324647
21 Radiofrequency Endoscopic Ablation With Ultrasound Guidance: a Non-surgical Treatment for Aldosterone-producing Adenomas Recruiting NCT03405025 Not Applicable
22 Effect of Chronic Catecholamine Overproduction on Brown Adipose Tissue Recruiting NCT01949714
23 Adrenalectomy Versus Follow-up in Patients With Subclinical Cushings Syndrome Recruiting NCT01246739 Not Applicable
24 Quality of Life, Fatigue and Cognitive, Affective and Emotional Dysfunction in Patients With Cushing's Syndrome Recruiting NCT03211624
25 Clinical and Molecular Characteristics of Primary Aldosteronism in Blacks Recruiting NCT03374215
26 Glucose Metabolism in Subjects With Aldosterone-Producing Adenomas Recruiting NCT02362308 Not Applicable mineralocorticoid receptor antagonist
27 Renal Sympathetic Denervation From The Adventitia on Hypertension Recruiting NCT02642445 Not Applicable
28 Study of Adrenal Gland Tumors Recruiting NCT00005927
29 Prospective Study Assessing Blood Pressure and Other Outcomes Post-treatment in Patients With Primary Aldosteronism Recruiting NCT03174847 Mineralocorticoid Receptor Antagonists
30 Morbidity and Mortality in Autonomous Cortisol Secretion Active, not recruiting NCT03919734
31 Radiofrequency Ablation for Aldosterone-producting Adenoma in Patients With Primary Aldosteronism Active, not recruiting NCT02756754 Not Applicable
32 Expression of Different Proliferation Biomarkers in Adreno-cortical Tumors Active, not recruiting NCT02747355
33 A Prospective Cohort Study for Patients With Adrenal Diseases Not yet recruiting NCT03474237
34 Rapid Cortisol Assay in Adrenal Vein Sampling Not yet recruiting NCT03449797 Not Applicable
35 Macrolides for KCNJ5 - Mutated Aldosterone-Producing Adenoma (MAPA) Not yet recruiting NCT03414918 Not Applicable Clarithromycin
36 A Study to Confirm Recurrent or Persistent Cushing's Syndrome in Patients With Signs or Symptoms of Hypercortisolemia Terminated NCT00796783 Cushing's syndrome confirmation

Search NIH Clinical Center for Adrenal Cortical Adenoma

Sources

Genetic Tests for Adrenal Cortical Adenoma

About this section
Sources

Anatomical Context for Adrenal Cortical Adenoma

About this section

MalaCards organs/tissues related to Adrenal Cortical Adenoma:

42
Cortex, Adrenal Cortex, Adrenal Gland, Thyroid, Testes, Breast, Endothelial
Sources

Publications for Adrenal Cortical Adenoma

About this section

Articles related to Adrenal Cortical Adenoma:

(show top 50) (show all 276)
# Title Authors Year
1
18-Oxocortisol Synthesis in Aldosterone-Producing Adrenocortical Adenoma and Significance of KCNJ5 Mutation Status. ( 31006333 )
2019
2
Incidental retroperitoneal oncocytoma (Ectopic oncocytic adrenocortical adenoma): Case report and review of the literature. ( 30706878 )
2019
3
Exacerbation of Cushing's syndrome during pregnancy: stimulation of a cortisol-secreting adrenocortical adenoma by ACTH originating from the foeto-placental unit. ( 30738017 )
2019
4
Tubulopapillary adrenocortical adenoma in a patient with familial adenomatous polyposis: a morphologic, ultrastructural, and molecular study. ( 30172912 )
2019
5
An ectopic adrenocortical adenoma in renal hilum presenting with Cushing's syndrome: A case report and literature review. ( 30557981 )
2018
6
An Ectopic Cortisol-Producing Adrenocortical Adenoma Masquerading as a Liposarcoma in the Pararenal Space. ( 30112868 )
2018
7
Florid hyperandrogenism due to a benign adrenocortical adenoma. ( 30061126 )
2018
8
Adrenocortical adenoma manifesting as false-positive iodine accumulation in a patient with history of thyroid carcinoma. ( 30108672 )
2018
9
Tumor microenvironment in functional adrenocortical adenomas: immune cell infiltration in cortisol-producing adrenocortical adenoma. ( 29596893 )
2018
10
Rebound thymic hyperplasia after adrenalectomy in a patient with Cushing syndrome caused by adrenocortical adenoma: A case report. ( 29642186 )
2018
11
MiR-193a-3p functions as a tumour suppressor in human aldosterone-producing adrenocortical adenoma by down-regulating CYP11B2. ( 29665181 )
2018
12
Testosterone- and Cortisol-secreting Oncocytic Adrenocortical Adenoma in the Pediatric Age-group. ( 29426273 )
2018
13
Common module analysis reveals prospective targets and mechanisms of pediatric adrenocortical adenoma and carcinoma. ( 29435068 )
2018
14
Does IGF-1 play a role in the etiopathogenesis of non-functioning adrenocortical adenoma? ( 29542030 )
2018
15
Adrenal Collision Tumor Composed of Adrenocortical Adenoma and Pheochromocytoma. ( 29363662 )
2018
16
Enlarging hypermetabolic nodule: benign non-functional adrenocortical adenoma. ( 29248879 )
2017
17
Primary Hyperaldosteronism Due to Adrenocortical Adenoma: a Case Report. ( 29093236 )
2017
18
Pheochromocytoma with Synchronous Ipsilateral Adrenal Cortical Adenoma. ( 28762170 )
2017
19
A exceptional collision tumor of primary adrenal angiosarcoma and non-functioning adrenocortical adenoma. ( 28551383 )
2017
20
Myxoid Adrenocortical Adenoma: A report of two cases and literature review. ( 28559117 )
2017
21
Central Precocious Puberty Secondary to Adrenocortical Adenoma in a Female Child: Case Report and Review of the Literature. ( 28578183 )
2017
22
Differentiating pheochromocytoma from lipid-poor adrenocortical adenoma by CT texture analysis: feasibility study. ( 28357529 )
2017
23
Spinal adrenal cortical adenoma associated with Beckwith-Wiedemann syndrome: case report and review of the literature. ( 28365908 )
2017
24
Expression of CYP11B2 in Aldosterone-Producing Adrenocortical Adenoma: Regulatory Mechanisms and Clinical Significance. ( 27853054 )
2016
25
Intrarenal Adrenocortical Adenoma Treated by Robotic Partial Nephrectomy with Adrenalectomy. ( 27579413 )
2016
26
Steroidogenic Acute Regulatory Protein Overexpression Correlates with Protein Kinase A Activation in Adrenocortical Adenoma. ( 27606678 )
2016
27
Ectopic adrenocortical adenoma in the renal hilum: a case report and literature review. ( 27094262 )
2016
28
Resolution of the physical features of Cushing's syndrome in a patient with a cortisol secreting adrenocortical adenoma after unilateral adrenalectomy. ( 27126097 )
2016
29
Myxoid adrenal cortical adenoma in an infant: An unusual morphology. ( 26881659 )
2015
30
Aggressive spinal glioblastoma in a child with adrenocortical adenoma--Case report and review of literature. ( 26960510 )
2015
31
Cushing's syndrome during pregnancy caused by adrenal cortical adenoma: a case report and literature review. ( 26271293 )
2015
32
Clinical and pathological analysis of 116 cases of adult adrenal cortical adenoma and literature review. ( 26064059 )
2015
33
A Case Report of Adrenocortical Adenoma Mimicking Congenital Adrenal Hyperplasia in a Young Girl. ( 26107677 )
2015
34
Adrenal renal fusion confusion: a case report of an adrenal cortical adenoma with adrenal-renal fusion. ( 25757409 )
2015
35
An Unusual Adrenal Cortical Nodule: Composite Adrenal Cortical Adenoma and Adenomatoid Tumor. ( 25861051 )
2015
36
Pseudomyocardial infarction caused by adrenocortical adenoma. ( 25708968 )
2015
37
Adrenal cortical adenoma with the maximal diameter greater than 5 cm: can they be differentiated from adrenal cortical carcinoma by CT? ( 25419344 )
2014
38
Ectopic cortisol-producing adrenocortical adenoma in the renal hilum: histopathological features and steroidogenic enzyme profile. ( 25120827 )
2014
39
A mimic of sarcomatoid adrenal cortical carcinoma: epithelioid angiosarcoma occurring in adrenal cortical adenoma. ( 25246132 )
2014
40
Myxoid adrenocortical adenoma: magnetic resonance imaging and pathology correlation. ( 24643431 )
2014
41
Epithelioid angiosarcoma arising in an adrenal cortical adenoma: a case report and review of the literature. ( 24771258 )
2014
42
Occurrence of De Quervain's Thyroiditis after Resolution of Hypercortisolism following Pasireotide Treatment for Cushing's Disease and Surgery for an Adrenocortical Adenoma: Report of Two Cases. ( 24847470 )
2014
43
Myelolipoma associated with adrenocortical adenoma: an unusual cause of Cushing's syndrome. ( 23916698 )
2014
44
Ectopic adrenal cortical adenoma in the gastric wall: case report. ( 23429246 )
2013
45
Adrenal cortical adenoma: the fourth component of the Carney triad and an association with subclinical Cushing syndrome. ( 23681078 )
2013
46
Adrenal cortical adenoma arising from an adrenohepatic union. ( 23686455 )
2013
47
Primary adrenal angiosarcoma and functioning adrenocortical adenoma: an exceptional combined tumor. ( 22048963 )
2012
48
A unique case of synchronous functional adrenocortical adenoma and myelolipoma within the ectopic adrenal cortex in a child with Beckwith-Wiedemann syndrome. ( 22309953 )
2012
49
An unusual presentation of Carney complex with diffuse primary pigmented nodular adrenocortical disease on one adrenal gland and a nonpigmented adrenocortical adenoma and focal primary pigmented nodular adrenocortical disease on the other. ( 22785148 )
2012
50
Retroperitoneal adrenal-sparing surgery for the treatment of Cushing's syndrome caused by adrenocortical adenoma: 8-year experience with 87 patients. ( 22382766 )
2012
Sources

Variations for Adrenal Cortical Adenoma

About this section
Sources

Expression for Adrenal Cortical Adenoma

About this section
Search GEO for disease gene expression data for Adrenal Cortical Adenoma.
Sources

Pathways for Adrenal Cortical Adenoma

About this section

Pathways related to Adrenal Cortical Adenoma according to GeneCards Suite gene sharing:

(show all 13)
# Super pathways Score Top Affiliating Genes
1
Cytochrome P450 - arranged by substrate type 67
Show member pathways
 12.83 CYP11A1 CYP11B1 CYP17A1 POMC SULT2A1
2
DAG and IP3 signaling 67
Show member pathways
 12.74 CYP11A1 NR5A1 POMC PRKAR1A
3
Aldosterone synthesis and secretion 38
Show member pathways
 11.97 CYP11A1 CYP11B1 CYP17A1 MC2R NR5A1 POMC
4
G alpha (s) signalling events 67
11.74 GIPR MC2R POMC
5
Diseases of metabolism 67
Show member pathways
 11.51 CYP11A1 MC2R POMC
6
Corticotropin-releasing hormone signaling pathway 1
11.43 CYP11A1 CYP11B1 POMC SULT2A1
7
Steroid hormone biosynthesis 38
Show member pathways
 11.32 CYP11A1 CYP11B1 CYP17A1
8
Ovarian steroidogenesis 38
11.2 CYP11A1 CYP17A1
9
Metabolism of steroid hormones 67
Show member pathways
 11.2 CYP11A1 CYP11B1 CYP17A1 POMC
10
Androstenedione and testosterone biosynthesis and metabolism p.1 23
Show member pathways
 11.17 CYP11B1 CYP17A1 SULT2A1
11
Melanocyte Development and Pigmentation 65
11.11 POMC PRKAR1A
12
Ovarian Infertility Genes 1
10.98 INHA NR5A1
13
superpathway of steroid hormone biosynthesis 1
Show member pathways
 10.8 CYP11B1 CYP17A1
Sources

GO Terms for Adrenal Cortical Adenoma

About this section

Biological processes related to Adrenal Cortical Adenoma according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 steroid biosynthetic process GO:0006694 9.43 CYP11A1 CYP11B1 CYP17A1
2 generation of precursor metabolites and energy GO:0006091 9.4 GIPR POMC
3 cellular response to peptide hormone stimulus GO:0071375 9.37 CYP11A1 CYP11B1
4 C21-steroid hormone biosynthetic process GO:0006700 9.32 CYP11A1 CYP11B1
5 steroid metabolic process GO:0008202 9.26 CYP11A1 CYP11B1 CYP17A1 SULT2A1
6 sterol metabolic process GO:0016125 9.16 CYP11A1 CYP11B1
7 glucocorticoid biosynthetic process GO:0006704 8.8 CYP11A1 CYP11B1 CYP17A1

Molecular functions related to Adrenal Cortical Adenoma according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 heme binding GO:0020037 9.33 CYP11A1 CYP11B1 CYP17A1
2 iron ion binding GO:0005506 9.13 CYP11A1 CYP11B1 CYP17A1
3 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen GO:0016705 8.8 CYP11A1 CYP11B1 CYP17A1
Sources

Sources for Adrenal Cortical Adenoma

About this section
3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
17 EFO
18 ExPASy
20 FMA
29 GO
30 GTR
31 HGMD
32 HMDB
33 HPO
34 ICD10
35 ICD10 via Orphanet
36 ICD9CM
37 IUPHAR
38 KEGG
39 LifeMap
41 LOVD
43 MedGen
45 MeSH
46 MESH via Orphanet
47 MGI
50 NCI
51 NCIt
52 NDF-RT
55 NINDS
56 Novoseek
58 OMIM
59 OMIM via Orphanet
63 PubMed
65 QIAGEN
70 SNOMED-CT via HPO
71 SNOMED-CT via Orphanet
72 TGDB
73 Tocris
74 UMLS
75 UMLS via Orphanet
The MalaCards human disease database index: 1-9 A B C D E F G H I J K L M N O P Q R S T U V W X Y Z
Content
Loading form....