MCID: ADR003
MIFTS: 27

Adrenal Neuroblastoma

Categories: Cancer diseases, Endocrine diseases, Neuronal diseases

Aliases & Classifications for Adrenal Neuroblastoma

MalaCards integrated aliases for Adrenal Neuroblastoma:

Name: Adrenal Neuroblastoma 12 15 70
Neuroblastoma of Adrenal Gland 12
Adrenal Gland Neuroblastoma 17

Classifications:



External Ids:

Disease Ontology 12 DOID:5718
NCIt 50 C4827
SNOMED-CT 67 281562007
UMLS 70 C0559460

Summaries for Adrenal Neuroblastoma

Disease Ontology : 12 An adrenal gland cancer that derives from immature neuroblastic cells.

MalaCards based summary : Adrenal Neuroblastoma, also known as neuroblastoma of adrenal gland, is related to adrenal carcinoma and neuroblastoma. An important gene associated with Adrenal Neuroblastoma is ENO2 (Enolase 2), and among its related pathways/superpathways is Neuroscience. Affiliated tissues include adrenal gland, lung and pineal, and related phenotype is nervous system.

Related Diseases for Adrenal Neuroblastoma

Diseases related to Adrenal Neuroblastoma via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50) (show all 233)
# Related Disease Score Top Affiliating Genes
1 adrenal carcinoma 31.6 SYP ENO2 CHGA
2 neuroblastoma 30.4 SYP NTRK1 MYCN ENO2 CHGA
3 retroperitoneal neuroblastoma 30.2 MYCN ENO2
4 gangliocytoma 30.1 SYP ENO2
5 hemangioma 29.6 SYP ENO2 CHGA
6 horseshoe kidney 29.6 SYP ENO2 CHGA
7 teratoma 29.5 SYP ENO2 CHGA
8 ganglioneuroblastoma 29.5 SYP NTRK1 MYCN ENO2
9 pheochromocytoma 28.8 SYP NTRK1 ENO2 CHGB CHGA
10 ganglioneuroma 28.8 SYP NTRK1 MYCN ENO2 CHGA
11 malignant melanocytic neoplasm of the peripheral nerve sheath 10.3 SYP ENO2
12 anal neuroendocrine tumor 10.3 SYP ENO2
13 optic nerve astrocytoma 10.3 SYP ENO2
14 cerebral neuroblastoma 10.3 SYP ENO2
15 neuronal intestinal dysplasia, type b 10.3 SYP ENO2
16 lung meningioma 10.3 SYP ENO2
17 sinonasal undifferentiated carcinoma 10.3 SYP ENO2
18 papillary tumor of the pineal region 10.3 SYP ENO2
19 cloacogenic carcinoma 10.3 SYP ENO2
20 pineal region teratoma 10.3 SYP ENO2
21 extraosseous ewings sarcoma-primitive neuroepithelial tumor 10.3 SYP ENO2
22 intracranial primitive neuroectodermal tumor 10.3 SYP ENO2
23 bile duct mucinous adenocarcinoma 10.3 SYP ENO2
24 nodular prostate 10.3 SYP ENO2
25 cerebellar liponeurocytoma 10.3 SYP ENO2
26 desmoplastic infantile ganglioglioma 10.3 SYP MYCN
27 cerebellopontine angle primitive neuroectodermal tumor 10.3 SYP ENO2
28 jejunal neoplasm 10.3 SYP ENO2
29 horner's syndrome 10.3 MYCN ENO2
30 myoblastoma 10.3 SYP ENO2
31 pineal parenchymal tumor of intermediate differentiation 10.3 SYP ENO2
32 kidney rhabdoid cancer 10.3 SYP ENO2
33 spinal cord oligodendroglioma 10.3 SYP ENO2
34 endobronchial leiomyoma 10.3 SYP ENO2
35 orbital cancer 10.3 SYP ENO2
36 extraosseous ewing sarcoma 10.3 SYP ENO2
37 small cell osteogenic sarcoma 10.3 SYP ENO2
38 endobronchial lipoma 10.3 SYP ENO2
39 rhabdoid meningioma 10.3 SYP ENO2
40 bladder lateral wall cancer 10.3 SYP ENO2
41 nasal cavity olfactory neuroblastoma 10.3 SYP ENO2
42 nodular medulloblastoma 10.3 SYP MYCN
43 cerebrovascular benign neoplasm 10.3 SYP ENO2
44 cerebellar medulloblastoma 10.3 SYP ENO2
45 askin's tumor 10.3 SYP ENO2
46 clear cell ependymoma 10.3 SYP ENO2
47 pineal gland cancer 10.3 SYP ENO2
48 cystic basal cell carcinoma 10.3 SYP ENO2
49 extraosseous chondrosarcoma 10.3 SYP ENO2
50 subleukemic leukemia 10.3 SYP ENO2

Graphical network of the top 20 diseases related to Adrenal Neuroblastoma:



Diseases related to Adrenal Neuroblastoma

Symptoms & Phenotypes for Adrenal Neuroblastoma

MGI Mouse Phenotypes related to Adrenal Neuroblastoma:

46
# Description MGI Source Accession Score Top Affiliating Genes
1 nervous system MP:0003631 9.23 CHGA CHGB EMC3 ENO2 MYCN NTRK1

Drugs & Therapeutics for Adrenal Neuroblastoma

Search Clinical Trials , NIH Clinical Center for Adrenal Neuroblastoma

Genetic Tests for Adrenal Neuroblastoma

Anatomical Context for Adrenal Neuroblastoma

MalaCards organs/tissues related to Adrenal Neuroblastoma:

40
Adrenal Gland, Lung, Pineal, Breast, Appendix, Spinal Cord, Ovary

Publications for Adrenal Neuroblastoma

Articles related to Adrenal Neuroblastoma:

(show top 50) (show all 203)
# Title Authors PMID Year
1
Metastatic, Bilateral Adrenal Neuroblastoma Presenting With Blindness Without Proptosis. 61
33512866 2021
2
Imaging of solid congenital abdominal masses: a review of the literature and practical approach to image interpretation. 61
33252758 2020
3
The feasibility of adrenal-sparing surgery in bilateral adrenal neuroblastoma. 61
32703624 2020
4
Single-Cell Characterization of Malignant Phenotypes and Developmental Trajectories of Adrenal Neuroblastoma. 61
32946775 2020
5
Anti-GD2 antibody and Vorinostat immunocombination therapy is highly effective in an aggressive orthotopic neuroblastoma model. 61
33457098 2020
6
Stage IV adrenal neuroblastoma with subcutaneous nodules in an infant: a case report. 61
32368803 2020
7
Pediatric Patients with Adrenal Neuroblastoma: A SEER Analysis, 2004-2013. 61
32167055 2020
8
Surgical Management of Giant L2 Adrenal Neuroblastoma in Adult Male. 61
33354378 2020
9
[Opsoclonus myoclonus syndrome secondary to abdominal neuroblastoma. Presentation of a pediatric clinical case]. 61
31758904 2019
10
Differences in Genomic Profiles and Outcomes Between Thoracic and Adrenal Neuroblastoma. 61
30793172 2019
11
Neuroblastoma presenting as hip pain and skull prominence in a child. 61
31695831 2019
12
Prenatal Diagnosis of Adrenal Neuroblastoma - Differential Diagnosis of Suprarenal Masses in the Third Trimester of Pregnancy. 61
31970317 2019
13
Systemic treatment of malignant gastrointestinal neuroectodermal tumour after childhood neuroblastoma: chemotherapy in malignant gastrointestinal neuroectodermal tumour. 61
31517734 2019
14
Neuroblastoma image-defined risk factors in adrenal neuroblastoma: role of radiologist. 61
31559184 2019
15
Adrenal neuroblastoma in an elderly adult: a case report and review of the literature. 61
31500669 2019
16
Surgical Excision of an Adrenal Neuroblastoma in a Dog. 61
31214604 2019
17
Comparison of long-term prognosis of laparoscopic and open adrenalectomy for local adrenal neuroblastoma in children. 61
29881893 2018
18
Irritable Hip as the Inaugural Symptom for Neuroblastoma. 61
30050714 2018
19
Fatal Congenital Retroperitoneal Neuroblastoma Diagnosed by Fetal Magnetic Resonance Imaging. 61
27997441 2017
20
Management of Neuroblastoma: ICMR Consensus Document. 61
28367616 2017
21
A Rare Case of Perinatal Intrarenal Neuroblastoma. 61
28085745 2017
22
Diagnosis of neonatal neuroblastoma with postmortem magnetic resonance imaging. 61
28228908 2017
23
Comparison of Clinical Features and Outcomes in Patients With Bilateral Versus Unilateral Adrenal Neuroblastoma. 61
27820129 2017
24
[An adrenal neuroblastoma regression diagnosed and followed by ultrasound: a case report]. 61
28255129 2017
25
Bilateral Cystic Adrenal Neuroblastoma with Cystic Liver metastasis. 61
28163998 2017
26
The Beta Subunit of Hemoglobin (HBB2/HBB) Suppresses Neuroblastoma Growth and Metastasis. 61
27793844 2017
27
Immune Thrombocytopenia in a Child with Neuroblastoma. 61
29062578 2017
28
Congenital Adrenal Neuroblastoma With and Without Cystic Change: Differentiating Features With an Emphasis on the of Value of Ultrasound. 61
27556888 2016
29
Survival of high-risk pediatric neuroblastoma patients in a developing country. 61
27235336 2016
30
Fetal neuroblastoma: ultrasonography and magnetic resonance imaging findings in the prenatal and postnatal IV-S stage. 61
27668206 2016
31
Mass spectrometry of gangliosides in extracranial tumors: Application to adrenal neuroblastoma. 61
27311552 2016
32
Bilateral adrenal neuroblastoma in the infant: Is it an image-defined risk factor? 61
27285992 2016
33
Laparoscopic treatment of adrenal masses in children: Report of two cases and review of literature. 61
27251661 2016
34
Rituximab treatment for relapsed opsoclonus-myoclonus syndrome. 61
26375512 2016
35
Focally Increased MIBG Activity in the Muscle: Real Lesion or LOVENOX Injection Artifact? 61
26402133 2016
36
Adrenal Neuroblastoma in an Adult: Effect of Radiotherapy on Local Progression after Surgical Removal. 61
27547479 2016
37
Hemophagocytic Lymphohistiocytosis After Initiation of Chemotherapy for Bilateral Adrenal Neuroblastoma. 61
26583611 2016
38
Prenatal diagnosis of congenital mesoblastic nephroma. 61
26430667 2015
39
Mature and immature teratoma: A report from the second Italian pediatric study. 61
25631333 2015
40
Adrenal neuroblastoma with metastatic mandibular mass: An unusual presentation. 61
26458598 2015
41
An infant with a diagnostically challenging hepatic teratoma, hypofibrinogenemia, and adrenal neuroblastoma: case report. 61
25756389 2015
42
Infection and integration of high-risk human papillomavirus in HPV-associated cancer cells. 61
25750043 2015
43
Unusual Differentiation to Pheochromocytoma-Like Cells in an Adrenal Neuroblastoma After Chemotherapy: A Case Report and Literature Review. 61
26207436 2015
44
Delayed renal dysfunction after total body irradiation in pediatric malignancies. 61
24914103 2014
45
Laparoscopic resection of adrenal neuroblastoma without image-defined risk factors: a prospective study on 21 consecutive pediatric patients. 61
24477777 2014
46
Stage 4S Bilateral Adrenal Neuroblastoma in a Newborn. 61
24834390 2014
47
(18)F-FDG-PET/CT, (123)I-MIBG and (99m)Tc-MDP whole-body scans, in detecting recurrence of an adult adrenal neuroblastoma. 61
24563879 2014
48
Clinical outcomes in children with adrenal neuroblastoma undergoing open versus laparoscopic adrenalectomy. 61
23932613 2013
49
Combination therapy with gefitinib and doxorubicin inhibits tumor growth in transgenic mice with adrenal neuroblastoma. 61
23930205 2013
50
[Laparoscopic adrenalectomy for neuroblastoma. Our serie and review of literature]. 61
24228353 2013

Variations for Adrenal Neuroblastoma

Expression for Adrenal Neuroblastoma

Search GEO for disease gene expression data for Adrenal Neuroblastoma.

Pathways for Adrenal Neuroblastoma

Pathways related to Adrenal Neuroblastoma according to GeneCards Suite gene sharing:

# Super pathways Score Top Affiliating Genes
1 11.46 SYP NTRK1 MYCN ENO2

GO Terms for Adrenal Neuroblastoma

Sources for Adrenal Neuroblastoma

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
17 EFO
18 ExPASy
19 FMA
20 GARD
28 GO
29 GTR
30 HMDB
31 HPO
32 ICD10
33 ICD10 via Orphanet
34 ICD9CM
35 IUPHAR
36 KEGG
37 LifeMap
39 LOVD
41 MedGen
44 MeSH
45 MESH via Orphanet
46 MGI
49 NCI
50 NCIt
51 NDF-RT
53 NINDS
54 Novoseek
56 OMIM via Orphanet
57 OMIM® (Updated 20-May-2021)
61 PubMed
63 QIAGEN
68 SNOMED-CT via HPO
69 Tocris
70 UMLS
71 UMLS via Orphanet
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