MCID: ADL099
MIFTS: 23

Adult Cystic Nephroma

Categories: Cancer diseases, Nephrological diseases

Aliases & Classifications for Adult Cystic Nephroma

MalaCards integrated aliases for Adult Cystic Nephroma:

Name: Adult Cystic Nephroma 12 15
Multilocular Cystic Nephroma, Mixed Epithelial Stromal Tumour and Renal Epithelial Stromal Tumour 12

Classifications:



External Ids:

Disease Ontology 12 DOID:2673
NCIt 49 C7504

Summaries for Adult Cystic Nephroma

Disease Ontology : 12 A nephroma that is characterized as a localized, well-circumscribed multilocular tumor lined by hobnail epithelium.

MalaCards based summary : Adult Cystic Nephroma, also known as multilocular cystic nephroma, mixed epithelial stromal tumour and renal epithelial stromal tumour, is related to nephroma and cervical adenomyoma. An important gene associated with Adult Cystic Nephroma is PGR (Progesterone Receptor), and among its related pathways/superpathways are Mesenchymal Stem Cells and Lineage-specific Markers and Dendritic Cells Developmental Lineage Pathway. Affiliated tissues include kidney, and related phenotypes are cardiovascular system and cellular

Related Diseases for Adult Cystic Nephroma

Diseases in the Adult Cystic Nephroma family:

Malignant Cystic Nephroma

Diseases related to Adult Cystic Nephroma via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50) (show all 153)
# Related Disease Score Top Affiliating Genes
1 nephroma 28.2 PGR MME MEST KIT DES ACTC1
2 cervical adenomyoma 10.2 PGR MME
3 adenomyoma 10.2 PGR MME
4 fallopian tube endometriosis 10.2 PGR MME
5 cervical benign neoplasm 10.2 PGR MME
6 uterine corpus adenosarcoma 10.2 PGR MME
7 cervical serous adenocarcinoma 10.2 PGR MME
8 breast leiomyoma 10.2 PGR MME
9 breast metaplastic carcinoma 10.2 PGR MME
10 vulvar leiomyoma 10.2 PGR MME
11 pancreatic mucinous cystadenoma 10.2 PGR MME
12 ovarian endometrioid stromal sarcoma 10.2 PGR MME
13 eccrine papillary adenocarcinoma 10.2 PGR MME
14 cutaneous adenocystic carcinoma 10.2 PGR MME
15 breast sarcoma 10.2 PGR MME
16 leiomyomatosis 10.2 PGR KIT
17 urethral benign neoplasm 10.2 PGR MME
18 cervical adenoma malignum 10.2 PGR MME
19 breast osteosarcoma 10.2 PGR MME
20 intraductal breast benign neoplasm 10.2 PGR MME
21 breast benign neoplasm 10.2 PGR MME
22 vaginal cancer 10.2 PGR MME
23 sweat gland benign neoplasm 10.2 PGR MME
24 liver leiomyoma 10.2 PGR KIT
25 mulchandani-bhoj-conlin syndrome 10.2 PGR MME
26 urethra leiomyoma 10.1 MME KIT
27 thoracic benign neoplasm 10.1 PGR MME
28 prostate stromal sarcoma 10.1 PGR KIT
29 mucocele of appendix 10.1 MME KIT
30 uterus leiomyosarcoma 10.1 PGR KIT
31 mixed epithelial stromal tumour 10.1 MME MEST
32 cribriform carcinoma 10.1 PGR KIT
33 ovarian mixed germ cell neoplasm 10.1 MME KIT
34 microglandular adenosis 10.1 PGR KIT
35 vulvar disease 10.1 PGR KIT
36 endobronchial leiomyoma 10.1 MME KIT
37 endometrial stromal tumor 10.1 PGR MME
38 tubular adenocarcinoma 10.1 PGR MME
39 uterine benign neoplasm 10.1 PGR MME
40 pleomorphic carcinoma 10.1 PGR KIT
41 reproductive organ benign neoplasm 10.1 PGR MME
42 calcifying aponeurotic fibroma 10.1 PGR ACTC1
43 glycogen-rich clear cell breast carcinoma 10.1 PGR ACTC1
44 kidney cortex disease 10.1 MME MEST
45 bizarre leiomyoma 10.1 PGR ACTC1
46 breast myoepithelial carcinoma 10.1 PGR ACTC1
47 myxoid leiomyosarcoma 10.1 PGR ACTC1
48 tonsil cancer 10.1 PGR KIT
49 adenomyosis 10.1 PGR MME
50 breast fibroadenoma 10.1 PGR MME

Graphical network of the top 20 diseases related to Adult Cystic Nephroma:



Diseases related to Adult Cystic Nephroma

Symptoms & Phenotypes for Adult Cystic Nephroma

MGI Mouse Phenotypes related to Adult Cystic Nephroma:

45
# Description MGI Source Accession Score Top Affiliating Genes
1 cardiovascular system MP:0005385 9.55 ACTC1 DES KIT MEST PGR
2 cellular MP:0005384 9.43 ACTC1 DES KIT MEST MME PGR
3 muscle MP:0005369 9.02 ACTC1 DES KIT MEST PGR

Drugs & Therapeutics for Adult Cystic Nephroma

Interventional clinical trials:


# Name Status NCT ID Phase Drugs
1 Renal Tumors Classification, Biology, and Banking Study Suspended NCT00898365

Search NIH Clinical Center for Adult Cystic Nephroma

Genetic Tests for Adult Cystic Nephroma

Anatomical Context for Adult Cystic Nephroma

MalaCards organs/tissues related to Adult Cystic Nephroma:

40
Kidney

Publications for Adult Cystic Nephroma

Articles related to Adult Cystic Nephroma:

(show all 12)
# Title Authors PMID Year
1
Can contrast enhanced ultrasound differentiate benign cystic nephroma from malignant multicystic renal lesions? A case report. 61
31867215 2020
2
Tubulocystic renal cell carcinoma: a review of literature focused on radiological findings for differential diagnosis. 61
29796844 2018
3
Pediatric Cystic Nephroma Is Morphologically, Immunohistochemically, and Genetically Distinct From Adult Cystic Nephroma. 61
28177962 2017
4
Ultrasound Imaging of Cystic Nephroma. 61
28752022 2017
5
[Laparoscopic nephron-sparing surgery for treatment of complex cystic renal lesions]. 61
23073588 2012
6
Mixed epithelial and stromal tumor of the kidney: radiologic-pathologic correlation. 61
21071374 2010
7
Adult cystic nephroma: a case report and a review of the literature. 61
18555707 2009
8
[Clinicopathologic analysis of mixed epithelial and stromal tumor of kidney and adult cystic nephroma]. 61
19781188 2009
9
Adult cystic nephroma and mixed epithelial and stromal tumor of the kidney are the same disease entity: molecular and histologic evidence. 61
18971776 2009
10
Adult cystic nephroma and mixed epithelial and stromal tumor of the kidney: clinical, radiographic, and pathologic characteristics. 61
18313107 2008
11
Malignant mixed epithelial and stromal tumor of the kidney with rhabdoid features: report of a case including immunohistochemical, molecular genetic studies and comparison to morphologically similar renal tumors. 61
17707262 2007
12
Cystic nephroma (multilocular cyst) and mixed epithelial and stromal tumor of the kidney: a spectrum of the same entity? 61
16546041 2006

Variations for Adult Cystic Nephroma

Expression for Adult Cystic Nephroma

Search GEO for disease gene expression data for Adult Cystic Nephroma.

Pathways for Adult Cystic Nephroma

Pathways related to Adult Cystic Nephroma according to GeneCards Suite gene sharing:

# Super pathways Score Top Affiliating Genes
1 11.23 KIT DES
2 11.02 MME KIT
3 10.81 DES ACTC1
4 10.35 KIT ACTC1

GO Terms for Adult Cystic Nephroma

Biological processes related to Adult Cystic Nephroma according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 muscle filament sliding GO:0030049 8.62 DES ACTC1

Sources for Adult Cystic Nephroma

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
17 EFO
18 ExPASy
19 FMA
28 GO
29 GTR
30 HMDB
31 HPO
32 ICD10
33 ICD10 via Orphanet
34 ICD9CM
35 IUPHAR
36 KEGG
37 LifeMap
39 LOVD
41 MedGen
43 MeSH
44 MESH via Orphanet
45 MGI
48 NCI
49 NCIt
50 NDF-RT
53 NINDS
54 Novoseek
56 OMIM
57 OMIM via Orphanet
61 PubMed
63 QIAGEN
68 SNOMED-CT via HPO
69 TGDB
70 Tocris
71 UMLS
72 UMLS via Orphanet
Content
Loading form....